4XPNA

Crystal structure of protein phosphate 1 complexed with pp1 binding domain of gadd34
Total Genus 105
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
296
structure length
296
Chain Sequence
MGSLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural and Functional Analysis of the GADD34:PP1 eIF2 alpha Phosphatase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Serine/threonine-protein phosphatase PP1-alpha catalytic sub
total genus 105
structure length 296
sequence length 296
chains with identical sequence C
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2015-01-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
A PF16891 STPPase_N Serine-threonine protein phosphatase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 4xpnA00
4H2FA 3H64A 5JPFA 2USHA 3EGGA 3LL8A 4G9JA 1V73A 1USHA 3H66A 3C9FA 1SU1A 1G5BA 2Z72A 4V0XA 4JA9A 2QFPA 5HPEA 1AUIA 4Q7FA 4HD0A 1S8EA 2QFRA 4TUGA 1JK7A 3ZU0A 3EGHA 4O24A 5C1VA 3THNA 2NXFA 4H1SA 4FBWA 3P71C 4M0VA 4FCXA 2Q8UA 3RQZA 2WDEA 4ORAA 3V4YA 5DNYA 1XM7A 4ORBA 4H2IA 3RL3A 1WARA 2ZBMA 1UF3A 4LACC 4FBKA 4UT3B 3DSCA 3ICFA 4B2OA 3AV0A 1HPUA 2Z06A 4V0WA 1S95A 2R17A 4LTYA 2HY1A 2IE4C 2Z1AA 3E7AA 2BQ8X 3C5WC 1UTEA 4OR9A 3QFNA 3TGHA 1WAO1 2O8GA 4TUIA 2YVTA 4H2BA 3DSDA 4UWQA 3IVEA 3H60A 3QFOA 3JYFA 2GJUA 3E7BA 1OI8A 3H63A 3H69A 4WWLA 4XPNA 1QFCA 1S3LA 4DT2A 3HVQA 1IT6A 1M63A 5B8IA 4ORCA 5EQVA 2IAEC 3RL5A 2HYOA 5J28A 1OIEA 1II7A 4IYPC 4DHLA 3PSNA 3QFMA 4O5GA 3AUZA 3H61A 1FJMA 5INBA 1QHWA 4FBQA 3KBPA 1U32A 4YKEA 1S3NA 4I5NC 4JA7A 4KBPA 4LU9A 2NYMC 2WDFA 3THOB 4MOYA 4H1YP 1HP1A 4ZVZA 1TCOA 1XZWA 2NPPC 4ZX2A 4UT3A 4O43A 4DSYA 3IB8A 2NYLC 2AHDA 2JOGA 4MOVA 4V0VA 3RL4A 2P6BA 1MF8A 4NZVA 1OIDA 3H67A 5JJTA 2A22A 4UT2A 1NNWA 3GVEA 3N5UA 3QFKA 2BDXA 4J6OA 2XMOA 1S70A 3K7VC 2WDDA 1T70A 3ZTVA 1Z2WA 2IE3C 5JPEA 1Z2XA 3K7WC 2BCDA 2WDCA 3PSOA 2QJCA 4I5LC 4O4KA 3T1IA 3H68A 2HYPA 3CK2A 3DW8C 4IL1A 5F3WA 4H2GA 1HO5A 3FGAC 5GTUA 3QG5C 1S3MA 3IVDA 1T71A 1W24A 2O8AA 3IB7A 4KKZA 5IOHA 2CV9A 3H62B 2DFJA 4MP0A 4F0ZA 1KBPA 2KKNA
chains in the Genus database with same CATH superfamily
4H2FA 3H64A 5JPFA 2USHA 3EGGA 3LL8A 2YEQA 4G9JA 1V73A 1USHA 3H66A 3C9FA 1SU1A 1G5BA 2Z72A 4V0XA 4JA9A 2QFPA 5HPEA 2DXLA 1AUIA 4Q7FA 4HD0A 1S8EA 2QFRA 4TUGA 1JK7A 3ZU0A 2DXNA 3EGHA 4O24A 5C1VA 3THNA 2NXFA 4H1SA 4FBWA 3P71C 4M0VA 4FCXA 2Q8UA 3RQZA 2WDEA 4ORAA 3V4YA 5DNYA 1XM7A 4ORBA 4H2IA 3RL3A 1WARA 2ZBMA 1UF3A 4LACC 4FBKA 4UT3B 3DSCA 3ICFA 4B2OA 3AV0A 1HPUA 2Z06A 4V0WA 1S95A 2R17A 4LTYA 2HY1A 2IE4C 2Z1AA 3E7AA 2BQ8X 3C5WC 1UTEA 4OR9A 3QFNA 3TGHA 1WAO1 2O8GA 4TUIA 2YVTA 4H2BA 3E0JA 3DSDA 4UWQA 3IVEA 3H60A 3QFOA 3JYFA 2GJUA 3E7BA 1OI8A 2ZOAA 3H63A 3H69A 4WWLA 2ZO9B 4XPNA 1QFCA 1S3LA 4DT2A 3HVQA 1IT6A 1M63A 5B8IA 4ORCA 5EQVA 2IAEC 3RL5A 2HYOA 5J28A 1OIEA 1II7A 4IYPC 4DHLA 3PSNA 3QFMA 4O5GA 3AUZA 3H61A 1FJMA 5INBA 1QHWA 4FBQA 3KBPA 1U32A 4YKEA 1S3NA 4I5NC 4JA7A 4KBPA 4LU9A 2NYMC 2WDFA 3THOB 4MOYA 4H1YP 1HP1A 3FLOA 4ZVZA 1TCOA 1XZWA 2NPPC 4ZX2A 4UT3A 4O43A 4DSYA 3IB8A 2NYLC 2AHDA 2JOGA 4MOVA 4V0VA 3RL4A 2P6BA 1MF8A 4NZVA 1OIDA 3H67A 5JJTA 2A22A 4UT2A 1NNWA 3GVEA 3N5UA 3QFKA 2BDXA 4J6OA 2XMOA 1S70A 3K7VC 2WDDA 1T70A 3ZTVA 1Z2WA 2IE3C 5JPEA 1Z2XA 3D03A 2BCDA 2WDCA 3K7WC 2QJCA 3PSOA 4I5LC 4O4KA 3T1IA 3H68A 2HYPA 3CK2A 3DW8C 4IL1A 5F3WA 4H2GA 1HO5A 3FGAC 5GTUA 3QG5C 1S3MA 3IVDA 1T71A 1W24A 2O8AA 3IB7A 4KKZA 5IOHA 2CV9A 3H62B 2DFJA 4MP0A 4F0ZA 1KBPA 2KKNA
chains in the Genus database with same CATH topology
4H2FA 3H64A 5JPFA 2USHA 3EGGA 3LL8A 2YEQA 4G9JA 1V73A 1USHA 3H66A 3C9FA 1SU1A 1G5BA 2Z72A 4V0XA 4JA9A 2QFPA 5HPEA 2DXLA 1AUIA 4Q7FA 4HD0A 1S8EA 2QFRA 4TUGA 1JK7A 3ZU0A 2DXNA 3EGHA 4O24A 5C1VA 3THNA 2NXFA 4H1SA 4FBWA 3P71C 4M0VA 4FCXA 2Q8UA 3RQZA 2WDEA 4ORAA 3V4YA 5DNYA 1XM7A 4ORBA 4H2IA 3RL3A 1WARA 2ZBMA 1UF3A 4LACC 4FBKA 4UT3B 3DSCA 3ICFA 4B2OA 3AV0A 1HPUA 2Z06A 4V0WA 1S95A 2R17A 4LTYA 2HY1A 2IE4C 2Z1AA 3E7AA 2BQ8X 3C5WC 1UTEA 4OR9A 3QFNA 3TGHA 1WAO1 2O8GA 4TUIA 2YVTA 4H2BA 3E0JA 3DSDA 4UWQA 3IVEA 3H60A 3QFOA 3JYFA 2GJUA 3E7BA 1OI8A 2ZOAA 3H63A 3H69A 4WWLA 2ZO9B 4XPNA 1QFCA 1S3LA 4DT2A 3HVQA 1IT6A 1M63A 5B8IA 4ORCA 5EQVA 2IAEC 3RL5A 2HYOA 5J28A 1OIEA 1II7A 4IYPC 4DHLA 3PSNA 3QFMA 4O5GA 3AUZA 3H61A 1FJMA 5INBA 1QHWA 4FBQA 3KBPA 1U32A 4YKEA 1S3NA 4I5NC 4JA7A 4KBPA 4LU9A 2NYMC 2WDFA 3THOB 4MOYA 4H1YP 1HP1A 3FLOA 4ZVZA 1TCOA 1XZWA 2NPPC 4ZX2A 4UT3A 4O43A 4DSYA 3IB8A 2NYLC 2AHDA 2JOGA 4MOVA 4V0VA 3RL4A 2P6BA 1MF8A 4NZVA 1OIDA 3H67A 5JJTA 2A22A 4UT2A 1NNWA 3GVEA 3N5UA 3QFKA 2BDXA 4J6OA 2XMOA 1S70A 3K7VC 2WDDA 1T70A 3ZTVA 1Z2WA 2IE3C 5JPEA 1Z2XA 3D03A 2BCDA 2WDCA 3K7WC 2QJCA 3PSOA 4I5LC 4O4KA 3T1IA 3H68A 2HYPA 3CK2A 3DW8C 4IL1A 5F3WA 4H2GA 1HO5A 3FGAC 5GTUA 3QG5C 1S3MA 3IVDA 1T71A 1W24A 2O8AA 3IB7A 4KKZA 5IOHA 2CV9A 3H62B 2DFJA 4MP0A 4F0ZA 1KBPA 2KKNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4H2F A;  3H64 A;  5JPF A;  2USH A;  3EGG A;  3LL8 A;  4G9J A;  1V73 A;  1USH A;  3H66 A;  3C9F A;  1SU1 A;  1G5B A;  2Z72 A;  4V0X A;  4JA9 A;  2QFP A;  5HPE A;  1AUI A;  4Q7F A;  4HD0 A;  1S8E A;  2QFR A;  4TUG A;  1JK7 A;  3ZU0 A;  3EGH A;  4O24 A;  5C1V A;  3THN A;  2NXF A;  4H1S A;  4FBW A;  3P71 C;  4M0V A;  4FCX A;  2Q8U A;  3RQZ A;  2WDE A;  4ORA A;  3V4Y A;  5DNY A;  1XM7 A;  4ORB A;  4H2I A;  3RL3 A;  1WAR A;  2ZBM A;  1UF3 A;  4LAC C;  4FBK A;  4UT3 B;  3DSC A;  3ICF A;  4B2O A;  3AV0 A;  1HPU A;  2Z06 A;  4V0W A;  1S95 A;  2R17 A;  4LTY A;  2HY1 A;  2IE4 C;  2Z1A A;  3E7A A;  2BQ8 X;  3C5W C;  1UTE A;  4OR9 A;  3QFN A;  3TGH A;  1WAO 1;  2O8G A;  4TUI A;  2YVT A;  4H2B A;  3DSD A;  4UWQ A;  3IVE A;  3H60 A;  3QFO A;  3JYF A;  2GJU A;  3E7B A;  1OI8 A;  3H63 A;  3H69 A;  4WWL A;  4XPN A;  1QFC A;  1S3L A;  4DT2 A;  3HVQ A;  1IT6 A;  1M63 A;  5B8I A;  4ORC A;  5EQV A;  2IAE C;  3RL5 A;  2HYO A;  5J28 A;  1OIE A;  1II7 A;  4IYP C;  4DHL A;  3PSN A;  3QFM A;  4O5G A;  3AUZ A;  3H61 A;  1FJM A;  5INB A;  1QHW A;  4FBQ A;  3KBP A;  1U32 A;  4YKE A;  1S3N A;  4I5N C;  4JA7 A;  4KBP A;  4LU9 A;  2NYM C;  2WDF A;  3THO B;  4MOY A;  4H1Y P;  1HP1 A;  4ZVZ A;  1TCO A;  1XZW A;  2NPP C;  4ZX2 A;  4UT3 A;  4O43 A;  4DSY A;  3IB8 A;  2NYL C;  2AHD A;  2JOG A;  4MOV A;  4V0V A;  3RL4 A;  2P6B A;  1MF8 A;  4NZV A;  1OID A;  3H67 A;  5JJT A;  2A22 A;  4UT2 A;  1NNW A;  3GVE A;  3N5U A;  3QFK A;  2BDX A;  4J6O A;  2XMO A;  1S70 A;  3K7V C;  2WDD A;  1T70 A;  3ZTV A;  1Z2W A;  2IE3 C;  5JPE A;  1Z2X A;  3K7W C;  2BCD A;  2WDC A;  3PSO A;  2QJC A;  4I5L C;  4O4K A;  3T1I A;  3H68 A;  2HYP A;  3CK2 A;  3DW8 C;  4IL1 A;  5F3W A;  4H2G A;  1HO5 A;  3FGA C;  5GTU A;  3QG5 C;  1S3M A;  3IVD A;  1T71 A;  1W24 A;  2O8A A;  3IB7 A;  4KKZ A;  5IOH A;  2CV9 A;  3H62 B;  2DFJ A;  4MP0 A;  4F0Z A;  1KBP A;  2KKN A; 
#chains in the Genus database with same CATH topology
 4H2F A;  3H64 A;  5JPF A;  2USH A;  3EGG A;  3LL8 A;  2YEQ A;  4G9J A;  1V73 A;  1USH A;  3H66 A;  3C9F A;  1SU1 A;  1G5B A;  2Z72 A;  4V0X A;  4JA9 A;  2QFP A;  5HPE A;  2DXL A;  1AUI A;  4Q7F A;  4HD0 A;  1S8E A;  2QFR A;  4TUG A;  1JK7 A;  3ZU0 A;  2DXN A;  3EGH A;  4O24 A;  5C1V A;  3THN A;  2NXF A;  4H1S A;  4FBW A;  3P71 C;  4M0V A;  4FCX A;  2Q8U A;  3RQZ A;  2WDE A;  4ORA A;  3V4Y A;  5DNY A;  1XM7 A;  4ORB A;  4H2I A;  3RL3 A;  1WAR A;  2ZBM A;  1UF3 A;  4LAC C;  4FBK A;  4UT3 B;  3DSC A;  3ICF A;  4B2O A;  3AV0 A;  1HPU A;  2Z06 A;  4V0W A;  1S95 A;  2R17 A;  4LTY A;  2HY1 A;  2IE4 C;  2Z1A A;  3E7A A;  2BQ8 X;  3C5W C;  1UTE A;  4OR9 A;  3QFN A;  3TGH A;  1WAO 1;  2O8G A;  4TUI A;  2YVT A;  4H2B A;  3E0J A;  3DSD A;  4UWQ A;  3IVE A;  3H60 A;  3QFO A;  3JYF A;  2GJU A;  3E7B A;  1OI8 A;  2ZOA A;  3H63 A;  3H69 A;  4WWL A;  2ZO9 B;  4XPN A;  1QFC A;  1S3L A;  4DT2 A;  3HVQ A;  1IT6 A;  1M63 A;  5B8I A;  4ORC A;  5EQV A;  2IAE C;  3RL5 A;  2HYO A;  5J28 A;  1OIE A;  1II7 A;  4IYP C;  4DHL A;  3PSN A;  3QFM A;  4O5G A;  3AUZ A;  3H61 A;  1FJM A;  5INB A;  1QHW A;  4FBQ A;  3KBP A;  1U32 A;  4YKE A;  1S3N A;  4I5N C;  4JA7 A;  4KBP A;  4LU9 A;  2NYM C;  2WDF A;  3THO B;  4MOY A;  4H1Y P;  1HP1 A;  3FLO A;  4ZVZ A;  1TCO A;  1XZW A;  2NPP C;  4ZX2 A;  4UT3 A;  4O43 A;  4DSY A;  3IB8 A;  2NYL C;  2AHD A;  2JOG A;  4MOV A;  4V0V A;  3RL4 A;  2P6B A;  1MF8 A;  4NZV A;  1OID A;  3H67 A;  5JJT A;  2A22 A;  4UT2 A;  1NNW A;  3GVE A;  3N5U A;  3QFK A;  2BDX A;  4J6O A;  2XMO A;  1S70 A;  3K7V C;  2WDD A;  1T70 A;  3ZTV A;  1Z2W A;  2IE3 C;  5JPE A;  1Z2X A;  3D03 A;  2BCD A;  2WDC A;  3K7W C;  2QJC A;  3PSO A;  4I5L C;  4O4K A;  3T1I A;  3H68 A;  2HYP A;  3CK2 A;  3DW8 C;  4IL1 A;  5F3W A;  4H2G A;  1HO5 A;  3FGA C;  5GTU A;  3QG5 C;  1S3M A;  3IVD A;  1T71 A;  1W24 A;  2O8A A;  3IB7 A;  4KKZ A;  5IOH A;  2CV9 A;  3H62 B;  2DFJ A;  4MP0 A;  4F0Z A;  1KBP A;  2KKN A; 
#chains in the Genus database with same CATH homology
 4H2F A;  3H64 A;  5JPF A;  2USH A;  3EGG A;  3LL8 A;  2YEQ A;  4G9J A;  1V73 A;  1USH A;  3H66 A;  3C9F A;  1SU1 A;  1G5B A;  2Z72 A;  4V0X A;  4JA9 A;  2QFP A;  5HPE A;  2DXL A;  1AUI A;  4Q7F A;  4HD0 A;  1S8E A;  2QFR A;  4TUG A;  1JK7 A;  3ZU0 A;  2DXN A;  3EGH A;  4O24 A;  5C1V A;  3THN A;  2NXF A;  4H1S A;  4FBW A;  3P71 C;  4M0V A;  4FCX A;  2Q8U A;  3RQZ A;  2WDE A;  4ORA A;  3V4Y A;  5DNY A;  1XM7 A;  4ORB A;  4H2I A;  3RL3 A;  1WAR A;  2ZBM A;  1UF3 A;  4LAC C;  4FBK A;  4UT3 B;  3DSC A;  3ICF A;  4B2O A;  3AV0 A;  1HPU A;  2Z06 A;  4V0W A;  1S95 A;  2R17 A;  4LTY A;  2HY1 A;  2IE4 C;  2Z1A A;  3E7A A;  2BQ8 X;  3C5W C;  1UTE A;  4OR9 A;  3QFN A;  3TGH A;  1WAO 1;  2O8G A;  4TUI A;  2YVT A;  4H2B A;  3E0J A;  3DSD A;  4UWQ A;  3IVE A;  3H60 A;  3QFO A;  3JYF A;  2GJU A;  3E7B A;  1OI8 A;  2ZOA A;  3H63 A;  3H69 A;  4WWL A;  2ZO9 B;  4XPN A;  1QFC A;  1S3L A;  4DT2 A;  3HVQ A;  1IT6 A;  1M63 A;  5B8I A;  4ORC A;  5EQV A;  2IAE C;  3RL5 A;  2HYO A;  5J28 A;  1OIE A;  1II7 A;  4IYP C;  4DHL A;  3PSN A;  3QFM A;  4O5G A;  3AUZ A;  3H61 A;  1FJM A;  5INB A;  1QHW A;  4FBQ A;  3KBP A;  1U32 A;  4YKE A;  1S3N A;  4I5N C;  4JA7 A;  4KBP A;  4LU9 A;  2NYM C;  2WDF A;  3THO B;  4MOY A;  4H1Y P;  1HP1 A;  3FLO A;  4ZVZ A;  1TCO A;  1XZW A;  2NPP C;  4ZX2 A;  4UT3 A;  4O43 A;  4DSY A;  3IB8 A;  2NYL C;  2AHD A;  2JOG A;  4MOV A;  4V0V A;  3RL4 A;  2P6B A;  1MF8 A;  4NZV A;  1OID A;  3H67 A;  5JJT A;  2A22 A;  4UT2 A;  1NNW A;  3GVE A;  3N5U A;  3QFK A;  2BDX A;  4J6O A;  2XMO A;  1S70 A;  3K7V C;  2WDD A;  1T70 A;  3ZTV A;  1Z2W A;  2IE3 C;  5JPE A;  1Z2X A;  3D03 A;  2BCD A;  2WDC A;  3K7W C;  2QJC A;  3PSO A;  4I5L C;  4O4K A;  3T1I A;  3H68 A;  2HYP A;  3CK2 A;  3DW8 C;  4IL1 A;  5F3W A;  4H2G A;  1HO5 A;  3FGA C;  5GTU A;  3QG5 C;  1S3M A;  3IVD A;  1T71 A;  1W24 A;  2O8A A;  3IB7 A;  4KKZ A;  5IOH A;  2CV9 A;  3H62 B;  2DFJ A;  4MP0 A;  4F0Z A;  1KBP A;  2KKN A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...