4Y52L

Crystal structure of 5-carboxycytosine recognition by rna polymerase ii during transcription elongation.
Total Genus 0
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
0
sequence length
45
structure length
45
Chain Sequence
TLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex.
pubmed doi rcsb
molecule tags Transcription/dna/rna
molecule keywords DNA-directed RNA polymerase II subunit RPB1
structure length 45
sequence length 45
ec nomenclature
pdb deposition date 2015-02-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 4y52L00
5M3FL 4Y52L 2R7ZL 2B63L 1Y1WL 3GTLL 4A93L 2WB1P 1TWGL 5C4JL 2JA8L 5IP7L 3S14L 2NVQL 3GTOL 3S1RL 4BY1L 1I3QL 4A3DL 2JA7L 3HOXL 5M3ML 1TWAL 4C3JL 4A3IL 4A3JL 4A3FL 2E2JL 3H3VM 2NVTL 3HOWL 5M5XL 2NVYL 3K7AL 2R93L 2R92L 2VUML 3GTKL 3S16L 3I4ML 1WCML 1Y1VL 4BXXL 5IYCL 3S1QL 1TWHL 4A3CL 3M3YL 5IYBL 3S17L 3M4OL 4A3KL 2WAQP 4BY7L 5FLML 3FKIL 2PMZP 4A3GL 4C2M1 3S1NL 4A3EL 1K83L 2JA5L 1TWFL 3HOYL 4A3LL 4A3BL 4C3HL 3HOUL 4BBRL 3GTML 3HKZP 1TWCL 5C44L 2YU9L 3HOVL 1SFOL 5C3EL 1I6HL 4QIWP 3GTPL 5C4XL 1I50L 5M5YL 3RZOL 3CQZL 3PO2L 5M5WL 4BBSL 2JA6L 2NVXL 3H0GL 3HOZL 3S2HL 3RZDL 3S15L 4X6AL 2Y0SP 5IP9L 3I4NL 3GTQL 4C3IL 5FJ8L 2E2HL 3S2DL 5IYDL 3GTJL 4A3ML 1R9TL 3PO3L 3GTGL 4AYBP 3S1ML 2E2IL 4Y7NL
chains in the Genus database with same CATH superfamily
1NXEA 2CR8A 1B13A 4TVMA 1Y1WL 3GTLL 4AHYA 2WB1P 1TWGL 3LNLA 4JAEA 5IY0A 5IP7L 1SMMA 1T9PA 4U671 3GTOL 1I3QL 3KYWA 5GAGc 2JA7L 2VL6A 4ZN3B 3HOXL 4XXBB 5M3ML 4A3JL 3H3VM 1E8JA 3K7AL 1BRFA 1P7PA 5GAHc 1QQTA 2VUML 1B2OA 3S16L 3I4ML 1R0IA 4B8CD 4BXXL 4AI2A 4AR6A 5IYBL 2ERJA 3PKIA 2K2DA 2PPTA 2PMZP 3PIO1 3S1NL 4A3EL 1K83L 2JA5L 1DVBA 2JI2A 4JADA 1NNQA 3B0AB 2JI3A 1FHMA 3HOUL 1S24A 4AI3A 5JVG1 4LHNA 3A44A 3HKZP 6RXNA 3WWNB 2BE5D 2EY4E 3PZAA 1PZXA 2AYJA 2O5JD 4POFA 4QIWP 1C09A 2A69D 5MF6A 1RDVA 1I50L 1RB9A 1VZIA 3CQZL 3QVDA 3PO2L 5MGNA 2NYDA 3H9CA 1SMWA 1VCXA 3S2HL 2KKDA 2Y0SP 4ZN1B 5JVH1 5FJ8L 5IYDL 2PYAA 3LWRB 3PO3L 3HJWB 2V0FA 3S2DL 4Y7NL 5M3FL 2V0EA 4Y52L 2V3BB 1RDGA 2XJQA 2NVQL 3S1RL 4BY1L 4UY81 1BE7A 2C6AA 2C6BA 4A3DL 1ZRPA 2M4YA 2RDVA 1DX8A 4AR3A 1TWAL 4A3FL 3MPSA 4YWLA 5M5XL 4LHLA 1T9OA 2A6HD 4AHZA 1SMUA 3S1QL 1IRNA 4A3CL 3LWQB 3M3YL 3S17L 4JAGA 3FDJA 3FKIL 1S2ZA 1F4LA 2B5ID 2PSMC 4A3GL 1R0FA 5AI3A 5K2ME 1IROA 4E6YA 3WWLA 1PFYA 5AI2A 1TWCL 8RXNA 5C44L 1S30A 3GTPL 1PFUA 5MLC3 4YWMA 1H7VA 5M5WL 4BBSL 2JA6L 1BQ8A 3S15L 4X6AL 3SS2A 2MS3A 5IP9L 3I4NL 3GTQL 2E2HL 3J7Y1 3ZG6A 2A68D 3KYUA 3H97A 1LKPA 2APOB 3GTJL 1YK5A 4K9FA 1R9TL 1LKOA 3GTGL 3PWFA 3MQKB 3LPEB 2AUSB 2CKCA 3PKJA 3S1ML 1T9QA 2HVYC 1R0HA 5C4JL 3HJYB 3S14L 1BFYA 4GS7D 2Z3QB 1RYTA 3VPBE 1BQ9A 2QL0A 1RWDA 4AHXA 4A3IL 2M4VA 2NVTL 7RXNA 3HOWL 1OWBA 5RXNA 2NVYL 1IU5A 1YV1A 2XJPA 4V196 2XJTA 4JAFA 1QCVA 4BY7L 1B71A 5MFPA 2H12A 2GMGA 4ME3A 4C2M1 1B2JA 3KYYA 4WFN1 1TWFL 3HOYL 4A3LL 3RZTA 2ERSA 4C3HL 5AN9H 3GTML 3HOVL 1JYBA 1RYQA 2XJSA 3MSUA 3PIP1 5GAEc 3PL5A 1R0JA 2M6PA 3QQCE 4POGA 3RZ6A 3HAXC 2NVXL 2DSXA 3HOZL 4AHWA 2PVEA 1LKMA 3LWVB 1PFVA 4C3IL 5GADc 2PVXA 4A3ML 1WJVA 4AI0A 1QYBA 4XGHA 3RYGA 2E2IL 2R7ZL 2B63L 4A93L 5MFZA 2JA8L 1IU6A 5DM61 1YUXA 4AR4A 2CKAA 1CADA 2L0ZA 1FHHA 4TPUA 3JR7A 1PFWA 3LWOB 1YK4A 1R0GA 4C3JL 2E2JL 1LTLA 1VZGA 1Z92B 1YUZA 4RXNA 2Z3RB 2R93L 3P8BA 3H9BA 2LCQA 2R92L 3GTKL 2RFKB 1NXGA 1WCML 1Y1VL 1IW7D 5IYCL 1TWHL 2J9UB 2XJRA 3M4OL 4A3KL 3H99A 2WAQP 5FLML 3B08B 2A6ED 2M6OA 2XJVA 3K35A 3KYVA 4A3BL 2AQCA 5H1Sc 5EIOC 4BBRL 3NFPI 1OWCA 2YU9L 4G6BA 3KYXA 2HR5A 1CAAA 5C3EL 1SFOL 1I6HL 5C4XL 4AR5A 2XJUA 3P2AA 5M5YL 5EINC 3RZOL 5DM71 2KN9A 1ODHA 3H0GL 2JI1A 3RZDL 3J7Z1 1VZHA 3IU3I 2ZIXA 4AYBP 3LWPB 4AI1A
chains in the Genus database with same CATH topology
5M3FL 4Y52L 2R7ZL 2B63L 1Y1WL 3GTLL 4A93L 2WB1P 1TWGL 5C4JL 2JA8L 5IP7L 3S14L 2NVQL 3GTOL 3S1RL 4BY1L 1I3QL 4A3DL 2JA7L 3HOXL 5M3ML 1TWAL 4C3JL 4A3IL 4A3JL 4A3FL 2E2JL 3H3VM 2NVTL 3HOWL 5M5XL 2NVYL 3K7AL 2R93L 2R92L 2VUML 3GTKL 3S16L 3I4ML 1WCML 1Y1VL 4BXXL 5IYCL 3S1QL 1TWHL 4A3CL 3M3YL 5IYBL 3S17L 3M4OL 4A3KL 2WAQP 4BY7L 5FLML 3FKIL 2PMZP 4A3GL 4C2M1 3S1NL 4A3EL 1K83L 2JA5L 1TWFL 3HOYL 4A3LL 4A3BL 4C3HL 3HOUL 4BBRL 3GTML 3HKZP 1TWCL 5C44L 2YU9L 3HOVL 1SFOL 5C3EL 1I6HL 4QIWP 3GTPL 5C4XL 1I50L 5M5YL 3RZOL 3CQZL 3PO2L 5M5WL 4BBSL 2JA6L 2NVXL 3H0GL 3HOZL 3S2HL 3RZDL 3S15L 4X6AL 2Y0SP 5IP9L 3I4NL 3GTQL 4C3IL 5FJ8L 2E2HL 3S2DL 5IYDL 3GTJL 4A3ML 1R9TL 3PO3L 3GTGL 4AYBP 3S1ML 2E2IL 4Y7NL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5M3F L;  4Y52 L;  2R7Z L;  2B63 L;  1Y1W L;  3GTL L;  4A93 L;  2WB1 P;  1TWG L;  5C4J L;  2JA8 L;  5IP7 L;  3S14 L;  2NVQ L;  3GTO L;  3S1R L;  4BY1 L;  1I3Q L;  4A3D L;  2JA7 L;  3HOX L;  5M3M L;  1TWA L;  4C3J L;  4A3I L;  4A3J L;  4A3F L;  2E2J L;  3H3V M;  2NVT L;  3HOW L;  5M5X L;  2NVY L;  3K7A L;  2R93 L;  2R92 L;  2VUM L;  3GTK L;  3S16 L;  3I4M L;  1WCM L;  1Y1V L;  4BXX L;  5IYC L;  3S1Q L;  1TWH L;  4A3C L;  3M3Y L;  5IYB L;  3S17 L;  3M4O L;  4A3K L;  2WAQ P;  4BY7 L;  5FLM L;  3FKI L;  2PMZ P;  4A3G L;  4C2M 1;  3S1N L;  4A3E L;  1K83 L;  2JA5 L;  1TWF L;  3HOY L;  4A3L L;  4A3B L;  4C3H L;  3HOU L;  4BBR L;  3GTM L;  3HKZ P;  1TWC L;  5C44 L;  2YU9 L;  3HOV L;  1SFO L;  5C3E L;  1I6H L;  4QIW P;  3GTP L;  5C4X L;  1I50 L;  5M5Y L;  3RZO L;  3CQZ L;  3PO2 L;  5M5W L;  4BBS L;  2JA6 L;  2NVX L;  3H0G L;  3HOZ L;  3S2H L;  3RZD L;  3S15 L;  4X6A L;  2Y0S P;  5IP9 L;  3I4N L;  3GTQ L;  4C3I L;  5FJ8 L;  2E2H L;  3S2D L;  5IYD L;  3GTJ L;  4A3M L;  1R9T L;  3PO3 L;  3GTG L;  4AYB P;  3S1M L;  2E2I L;  4Y7N L; 
#chains in the Genus database with same CATH topology
 1NXE A;  2CR8 A;  1B13 A;  4TVM A;  1Y1W L;  3GTL L;  4AHY A;  2WB1 P;  1TWG L;  3LNL A;  4JAE A;  5IY0 A;  5IP7 L;  1SMM A;  1T9P A;  4U67 1;  3GTO L;  1I3Q L;  3KYW A;  5GAG c;  2JA7 L;  2VL6 A;  4ZN3 B;  3HOX L;  4XXB B;  5M3M L;  4A3J L;  3H3V M;  1E8J A;  3K7A L;  1BRF A;  1P7P A;  5GAH c;  1QQT A;  2VUM L;  1B2O A;  3S16 L;  3I4M L;  1R0I A;  4B8C D;  4BXX L;  4AI2 A;  4AR6 A;  5IYB L;  2ERJ A;  3PKI A;  2K2D A;  2PPT A;  2PMZ P;  3PIO 1;  3S1N L;  4A3E L;  1K83 L;  2JA5 L;  1DVB A;  2JI2 A;  4JAD A;  1NNQ A;  3B0A B;  2JI3 A;  1FHM A;  3HOU L;  1S24 A;  4AI3 A;  5JVG 1;  4LHN A;  3A44 A;  3HKZ P;  6RXN A;  3WWN B;  2BE5 D;  2EY4 E;  3PZA A;  1PZX A;  2AYJ A;  2O5J D;  4POF A;  4QIW P;  1C09 A;  2A69 D;  5MF6 A;  1RDV A;  1I50 L;  1RB9 A;  1VZI A;  3CQZ L;  3QVD A;  3PO2 L;  5MGN A;  2NYD A;  3H9C A;  1SMW A;  1VCX A;  3S2H L;  2KKD A;  2Y0S P;  4ZN1 B;  5JVH 1;  5FJ8 L;  5IYD L;  2PYA A;  3LWR B;  3PO3 L;  3HJW B;  2V0F A;  3S2D L;  4Y7N L;  5M3F L;  2V0E A;  4Y52 L;  2V3B B;  1RDG A;  2XJQ A;  2NVQ L;  3S1R L;  4BY1 L;  4UY8 1;  1BE7 A;  2C6A A;  2C6B A;  4A3D L;  1ZRP A;  2M4Y A;  2RDV A;  1DX8 A;  4AR3 A;  1TWA L;  4A3F L;  3MPS A;  4YWL A;  5M5X L;  4LHL A;  1T9O A;  2A6H D;  4AHZ A;  1SMU A;  3S1Q L;  1IRN A;  4A3C L;  3LWQ B;  3M3Y L;  3S17 L;  4JAG A;  3FDJ A;  3FKI L;  1S2Z A;  1F4L A;  2B5I D;  2PSM C;  4A3G L;  1R0F A;  5AI3 A;  5K2M E;  1IRO A;  4E6Y A;  3WWL A;  1PFY A;  5AI2 A;  1TWC L;  8RXN A;  5C44 L;  1S30 A;  3GTP L;  1PFU A;  5MLC 3;  4YWM A;  1H7V A;  5M5W L;  4BBS L;  2JA6 L;  1BQ8 A;  3S15 L;  4X6A L;  3SS2 A;  2MS3 A;  5IP9 L;  3I4N L;  3GTQ L;  2E2H L;  3J7Y 1;  3ZG6 A;  2A68 D;  3KYU A;  3H97 A;  1LKP A;  2APO B;  3GTJ L;  1YK5 A;  4K9F A;  1R9T L;  1LKO A;  3GTG L;  3PWF A;  3MQK B;  3LPE B;  2AUS B;  2CKC A;  3PKJ A;  3S1M L;  1T9Q A;  2HVY C;  1R0H A;  5C4J L;  3HJY B;  3S14 L;  1BFY A;  4GS7 D;  2Z3Q B;  1RYT A;  3VPB E;  1BQ9 A;  2QL0 A;  1RWD A;  4AHX A;  4A3I L;  2M4V A;  2NVT L;  7RXN A;  3HOW L;  1OWB A;  5RXN A;  2NVY L;  1IU5 A;  1YV1 A;  2XJP A;  4V19 6;  2XJT A;  4JAF A;  1QCV A;  4BY7 L;  1B71 A;  5MFP A;  2H12 A;  2GMG A;  4ME3 A;  4C2M 1;  1B2J A;  3KYY A;  4WFN 1;  1TWF L;  3HOY L;  4A3L L;  3RZT A;  2ERS A;  4C3H L;  5AN9 H;  3GTM L;  3HOV L;  1JYB A;  1RYQ A;  2XJS A;  3MSU A;  3PIP 1;  5GAE c;  3PL5 A;  1R0J A;  2M6P A;  3QQC E;  4POG A;  3RZ6 A;  3HAX C;  2NVX L;  2DSX A;  3HOZ L;  4AHW A;  2PVE A;  1LKM A;  3LWV B;  1PFV A;  4C3I L;  5GAD c;  2PVX A;  4A3M L;  1WJV A;  4AI0 A;  1QYB A;  4XGH A;  3RYG A;  2E2I L;  2R7Z L;  2B63 L;  4A93 L;  5MFZ A;  2JA8 L;  1IU6 A;  5DM6 1;  1YUX A;  4AR4 A;  2CKA A;  1CAD A;  2L0Z A;  1FHH A;  4TPU A;  3JR7 A;  1PFW A;  3LWO B;  1YK4 A;  1R0G A;  4C3J L;  2E2J L;  1LTL A;  1VZG A;  1Z92 B;  1YUZ A;  4RXN A;  2Z3R B;  2R93 L;  3P8B A;  3H9B A;  2LCQ A;  2R92 L;  3GTK L;  2RFK B;  1NXG A;  1WCM L;  1Y1V L;  1IW7 D;  5IYC L;  1TWH L;  2J9U B;  2XJR A;  3M4O L;  4A3K L;  3H99 A;  2WAQ P;  5FLM L;  3B08 B;  2A6E D;  2M6O A;  2XJV A;  3K35 A;  3KYV A;  4A3B L;  2AQC A;  5H1S c;  5EIO C;  4BBR L;  3NFP I;  1OWC A;  2YU9 L;  4G6B A;  3KYX A;  2HR5 A;  1CAA A;  5C3E L;  1SFO L;  1I6H L;  5C4X L;  4AR5 A;  2XJU A;  3P2A A;  5M5Y L;  5EIN C;  3RZO L;  5DM7 1;  2KN9 A;  1ODH A;  3H0G L;  2JI1 A;  3RZD L;  3J7Z 1;  1VZH A;  3IU3 I;  2ZIX A;  4AYB P;  3LWP B;  4AI1 A; 
#chains in the Genus database with same CATH homology
 5M3F L;  4Y52 L;  2R7Z L;  2B63 L;  1Y1W L;  3GTL L;  4A93 L;  2WB1 P;  1TWG L;  5C4J L;  2JA8 L;  5IP7 L;  3S14 L;  2NVQ L;  3GTO L;  3S1R L;  4BY1 L;  1I3Q L;  4A3D L;  2JA7 L;  3HOX L;  5M3M L;  1TWA L;  4C3J L;  4A3I L;  4A3J L;  4A3F L;  2E2J L;  3H3V M;  2NVT L;  3HOW L;  5M5X L;  2NVY L;  3K7A L;  2R93 L;  2R92 L;  2VUM L;  3GTK L;  3S16 L;  3I4M L;  1WCM L;  1Y1V L;  4BXX L;  5IYC L;  3S1Q L;  1TWH L;  4A3C L;  3M3Y L;  5IYB L;  3S17 L;  3M4O L;  4A3K L;  2WAQ P;  4BY7 L;  5FLM L;  3FKI L;  2PMZ P;  4A3G L;  4C2M 1;  3S1N L;  4A3E L;  1K83 L;  2JA5 L;  1TWF L;  3HOY L;  4A3L L;  4A3B L;  4C3H L;  3HOU L;  4BBR L;  3GTM L;  3HKZ P;  1TWC L;  5C44 L;  2YU9 L;  3HOV L;  1SFO L;  5C3E L;  1I6H L;  4QIW P;  3GTP L;  5C4X L;  1I50 L;  5M5Y L;  3RZO L;  3CQZ L;  3PO2 L;  5M5W L;  4BBS L;  2JA6 L;  2NVX L;  3H0G L;  3HOZ L;  3S2H L;  3RZD L;  3S15 L;  4X6A L;  2Y0S P;  5IP9 L;  3I4N L;  3GTQ L;  4C3I L;  5FJ8 L;  2E2H L;  3S2D L;  5IYD L;  3GTJ L;  4A3M L;  1R9T L;  3PO3 L;  3GTG L;  4AYB P;  3S1M L;  2E2I L;  4Y7N L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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