5C4JL

Crystal structure of a transcribing rna polymerase ii complex reveals a complete transcription bubble
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
43
structure length
43
Chain Sequence
KYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
pubmed doi rcsb
molecule tags Transferase/dna/rna
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 3
structure length 43
sequence length 43
ec nomenclature
pdb deposition date 2015-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 5c4jL00
3FKIL 2JA7L 2E2JL 4C3HL 4C3IL 4A3DL 4QIWP 5C44L 5C4XL 5IYDL 3GTML 3HKZP 3PO2L 3I4NL 3M3YL 5M3FL 4A3BL 2JA5L 3GTGL 3RZDL 4A3KL 3PO3L 1TWFL 3M4OL 4A3LL 3I4ML 5C4JL 2JA8L 2YU9L 5IP9L 3S15L 3HOWL 4A3IL 5FLML 3GTJL 1R9TL 4A93L 5IP7L 3GTPL 5IYBL 4BY7L 2E2HL 1K83L 3GTLL 4BBRL 2NVTL 3S14L 4C3JL 2WAQP 3RZOL 1WCML 4A3EL 2R92L 4A3GL 3HOYL 4Y52L 4BXXL 2B63L 1TWCL 3S1QL 1I50L 2VUML 3GTKL 3H0GL 3H3VM 1TWGL 3K7AL 3S1NL 1TWHL 3GTOL 3S1ML 2WB1P 2PMZP 3S16L 3S2HL 3S17L 4A3JL 2R7ZL 5M5YL 2R93L 5M3ML 5M5XL 1I6HL 2NVYL 4AYBP 2NVXL 3HOVL 3HOZL 4BY1L 5C3EL 2E2IL 1I3QL 4Y7NL 4A3CL 3HOXL 4X6AL 2JA6L 1SFOL 1TWAL 3S2DL 3GTQL 4BBSL 3HOUL 4A3ML 5M5WL 4C2M1 5FJ8L 3S1RL 1Y1WL 3CQZL 1Y1VL 2Y0SP 4A3FL 5IYCL 2NVQL
chains in the Genus database with same CATH superfamily
2M4VA 2XJSA 2A6HD 3H97A 3PKJA 1S24A 2J9UB 3GTML 3HKZP 4ZN3B 1LTLA 3M3YL 5M3FL 2JA5L 1TWFL 4A3LL 2MS3A 1RYQA 3MSUA 1QQTA 1R0FA 2AQCA 2VL6A 4A3IL 4AHZA 1S30A 1BQ9A 3PL5A 5IYBL 1FHMA 3MPSA 1K83L 1RB9A 2K2DA 1E8JA 1IW7D 2WAQP 2EY4E 2R92L 4A3GL 2JI3A 2B63L 1R0HA 8RXNA 2VUML 3GTKL 5RXNA 2GMGA 1IU6A 1R0JA 3RYGA 1DX8A 5M5YL 5M5XL 1F4LA 1SMUA 2M6OA 4BY1L 4A3CL 3HOXL 5IY0A 4K9FA 1B2JA 3K35A 1PZXA 3KYUA 1RDGA 2LCQA 4AR5A 4POGA 2A68D 1T9OA 1YV1A 5JVH1 3QQCE 5FJ8L 3LWPB 1QYBA 1DVBA 3CQZL 4POFA 2Y0SP 2KKDA 2V0EA 5DM61 3PIP1 3RZTA 4LHLA 2B5ID 5GAEc 3H99A 4UY81 2JA7L 4C3HL 2RFKB 1BE7A 4A3DL 5C44L 5C4XL 2CR8A 2XJVA 5IYDL 2PSMC 5MLC3 6RXNA 1C09A 1BQ8A 3GTGL 5AN9H 1YUXA 2AUSB 3RZDL 4AHXA 4A3KL 3PO3L 3M4OL 3I4ML 2XJQA 2Z3QB 5C4JL 1RYTA 1RDVA 4JADA 5IP9L 3S15L 3HOWL 3HJYB 5FLML 3H9CA 1QCVA 3IU3I 2PVXA 1R0GA 3HJWB 4BBRL 2NVTL 4C3JL 1WCML 4A3EL 4U671 1R0IA 1VZHA 3VPBE 2JI2A 1CADA 2CKCA 4JAFA 4E6YA 2ERJA 1LKOA 7RXNA 3S1NL 3KYWA 5EIOC 3WWNB 3GTOL 4YWLA 2PMZP 2HR5A 3S17L 4GS7D 5GADc 2CKAA 3HOZL 3LPEB 1PFVA 2E2IL 1I3QL 5AI3A 3GTQL 2XJPA 4A3ML 3KYVA 3S1RL 3PZAA 1Y1WL 2PYAA 3KYXA 3J7Y1 3J7Z1 4A3FL 5IYCL 5MF6A 1ZRPA 3LWVB 2NVQL 2RDVA 4G6BA 2AYJA 1B71A 3FKIL 2XJRA 3FDJA 2E2JL 4C3IL 3B08B 3P2AA 4WFN1 1PFWA 2KN9A 1BFYA 4B8CD 4A3BL 1IROA 1ODHA 2V0FA 5AI2A 3LWOB 1YUZA 4AR3A 4RXNA 2JA8L 3WWLA 1SMMA 4AHYA 1VCXA 4ZN1B 4AI3A 1OWCA 3GTJL 1R9TL 5IP7L 3GTPL 4BY7L 5DM71 4V196 4LHNA 3RZ6A 1RWDA 2O5JD 1YK5A 1PFYA 1PFUA 1S2ZA 1TWCL 3PKIA 4YWMA 4AI2A 3H3VM 1T9QA 3LWRB 2BE5D 2XJTA 2WB1P 1P7PA 3S2HL 4XGHA 4A3JL 2R7ZL 3H9BA 1JYBA 1I6HL 2NVYL 2NVXL 3P8BA 1NXEA 4Y7NL 1H7VA 4X6AL 2JA6L 3LNLA 3A44A 1SFOL 1YK4A 3HAXC 4ME3A 5JVG1 3KYYA 4TPUA 1SMWA 2QL0A 5MFZA 1WJVA 3JR7A 5H1Sc 1BRFA 3PWFA 1IRNA 1VZIA 5MFPA 2DSXA 4QIWP 4AR4A 2HVYC 3PO2L 1LKMA 3I4NL 3QVDA 4TVMA 4AHWA 1B2OA 3SS2A 2V3BB 2YU9L 3MQKB 2A6ED 4AR6A 4A93L 3LWQB 1B13A 2E2HL 2PPTA 3GTLL 3RZOL 3S14L 1FHHA 5GAGc 4AI1A 3HOYL 4Y52L 5EINC 4BXXL 2ERSA 3S1QL 2APOB 1I50L 3H0GL 1TWGL 3K7AL 1IU5A 1TWHL 1CAAA 3S1ML 1Z92B 3S16L 5GAHc 2NYDA 2ZIXA 4JAEA 2L0ZA 1VZGA 2R93L 5M3ML 2M6PA 4AYBP 3HOVL 4JAGA 5C3EL 3PIO1 2A69D 4AI0A 5MGNA 1NNQA 1TWAL 3S2DL 3B0AB 1LKPA 2C6AA 4BBSL 3HOUL 1NXGA 3NFPI 4XXBB 5M5WL 2XJUA 4C2M1 2Z3RB 2H12A 2PVEA 2M4YA 1T9PA 5K2ME 1Y1VL 2C6BA 2JI1A 1OWBA 3ZG6A
chains in the Genus database with same CATH topology
3FKIL 2JA7L 2E2JL 4C3HL 4C3IL 4A3DL 4QIWP 5C44L 5C4XL 5IYDL 3GTML 3HKZP 3PO2L 3I4NL 3M3YL 5M3FL 4A3BL 2JA5L 3GTGL 3RZDL 4A3KL 3PO3L 1TWFL 3M4OL 4A3LL 3I4ML 5C4JL 2JA8L 2YU9L 5IP9L 3S15L 3HOWL 4A3IL 5FLML 3GTJL 1R9TL 4A93L 5IP7L 3GTPL 5IYBL 4BY7L 2E2HL 1K83L 3GTLL 4BBRL 2NVTL 3S14L 4C3JL 2WAQP 3RZOL 1WCML 4A3EL 2R92L 4A3GL 3HOYL 4Y52L 4BXXL 2B63L 1TWCL 3S1QL 1I50L 2VUML 3GTKL 3H0GL 3H3VM 1TWGL 3K7AL 3S1NL 1TWHL 3GTOL 3S1ML 2WB1P 2PMZP 3S16L 3S2HL 3S17L 4A3JL 2R7ZL 5M5YL 2R93L 5M3ML 5M5XL 1I6HL 2NVYL 4AYBP 2NVXL 3HOVL 3HOZL 4BY1L 5C3EL 2E2IL 1I3QL 4Y7NL 4A3CL 3HOXL 4X6AL 2JA6L 1SFOL 1TWAL 3S2DL 3GTQL 4BBSL 3HOUL 4A3ML 5M5WL 4C2M1 5FJ8L 3S1RL 1Y1WL 3CQZL 1Y1VL 2Y0SP 4A3FL 5IYCL 2NVQL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FKI L;  2JA7 L;  2E2J L;  4C3H L;  4C3I L;  4A3D L;  4QIW P;  5C44 L;  5C4X L;  5IYD L;  3GTM L;  3HKZ P;  3PO2 L;  3I4N L;  3M3Y L;  5M3F L;  4A3B L;  2JA5 L;  3GTG L;  3RZD L;  4A3K L;  3PO3 L;  1TWF L;  3M4O L;  4A3L L;  3I4M L;  5C4J L;  2JA8 L;  2YU9 L;  5IP9 L;  3S15 L;  3HOW L;  4A3I L;  5FLM L;  3GTJ L;  1R9T L;  4A93 L;  5IP7 L;  3GTP L;  5IYB L;  4BY7 L;  2E2H L;  1K83 L;  3GTL L;  4BBR L;  2NVT L;  3S14 L;  4C3J L;  2WAQ P;  3RZO L;  1WCM L;  4A3E L;  2R92 L;  4A3G L;  3HOY L;  4Y52 L;  4BXX L;  2B63 L;  1TWC L;  3S1Q L;  1I50 L;  2VUM L;  3GTK L;  3H0G L;  3H3V M;  1TWG L;  3K7A L;  3S1N L;  1TWH L;  3GTO L;  3S1M L;  2WB1 P;  2PMZ P;  3S16 L;  3S2H L;  3S17 L;  4A3J L;  2R7Z L;  5M5Y L;  2R93 L;  5M3M L;  5M5X L;  1I6H L;  2NVY L;  4AYB P;  2NVX L;  3HOV L;  3HOZ L;  4BY1 L;  5C3E L;  2E2I L;  1I3Q L;  4Y7N L;  4A3C L;  3HOX L;  4X6A L;  2JA6 L;  1SFO L;  1TWA L;  3S2D L;  3GTQ L;  4BBS L;  3HOU L;  4A3M L;  5M5W L;  4C2M 1;  5FJ8 L;  3S1R L;  1Y1W L;  3CQZ L;  1Y1V L;  2Y0S P;  4A3F L;  5IYC L;  2NVQ L; 
#chains in the Genus database with same CATH topology
 2M4V A;  2XJS A;  2A6H D;  3H97 A;  3PKJ A;  1S24 A;  2J9U B;  3GTM L;  3HKZ P;  4ZN3 B;  1LTL A;  3M3Y L;  5M3F L;  2JA5 L;  1TWF L;  4A3L L;  2MS3 A;  1RYQ A;  3MSU A;  1QQT A;  1R0F A;  2AQC A;  2VL6 A;  4A3I L;  4AHZ A;  1S30 A;  1BQ9 A;  3PL5 A;  5IYB L;  1FHM A;  3MPS A;  1K83 L;  1RB9 A;  2K2D A;  1E8J A;  1IW7 D;  2WAQ P;  2EY4 E;  2R92 L;  4A3G L;  2JI3 A;  2B63 L;  1R0H A;  8RXN A;  2VUM L;  3GTK L;  5RXN A;  2GMG A;  1IU6 A;  1R0J A;  3RYG A;  1DX8 A;  5M5Y L;  5M5X L;  1F4L A;  1SMU A;  2M6O A;  4BY1 L;  4A3C L;  3HOX L;  5IY0 A;  4K9F A;  1B2J A;  3K35 A;  1PZX A;  3KYU A;  1RDG A;  2LCQ A;  4AR5 A;  4POG A;  2A68 D;  1T9O A;  1YV1 A;  5JVH 1;  3QQC E;  5FJ8 L;  3LWP B;  1QYB A;  1DVB A;  3CQZ L;  4POF A;  2Y0S P;  2KKD A;  2V0E A;  5DM6 1;  3PIP 1;  3RZT A;  4LHL A;  2B5I D;  5GAE c;  3H99 A;  4UY8 1;  2JA7 L;  4C3H L;  2RFK B;  1BE7 A;  4A3D L;  5C44 L;  5C4X L;  2CR8 A;  2XJV A;  5IYD L;  2PSM C;  5MLC 3;  6RXN A;  1C09 A;  1BQ8 A;  3GTG L;  5AN9 H;  1YUX A;  2AUS B;  3RZD L;  4AHX A;  4A3K L;  3PO3 L;  3M4O L;  3I4M L;  2XJQ A;  2Z3Q B;  5C4J L;  1RYT A;  1RDV A;  4JAD A;  5IP9 L;  3S15 L;  3HOW L;  3HJY B;  5FLM L;  3H9C A;  1QCV A;  3IU3 I;  2PVX A;  1R0G A;  3HJW B;  4BBR L;  2NVT L;  4C3J L;  1WCM L;  4A3E L;  4U67 1;  1R0I A;  1VZH A;  3VPB E;  2JI2 A;  1CAD A;  2CKC A;  4JAF A;  4E6Y A;  2ERJ A;  1LKO A;  7RXN A;  3S1N L;  3KYW A;  5EIO C;  3WWN B;  3GTO L;  4YWL A;  2PMZ P;  2HR5 A;  3S17 L;  4GS7 D;  5GAD c;  2CKA A;  3HOZ L;  3LPE B;  1PFV A;  2E2I L;  1I3Q L;  5AI3 A;  3GTQ L;  2XJP A;  4A3M L;  3KYV A;  3S1R L;  3PZA A;  1Y1W L;  2PYA A;  3KYX A;  3J7Y 1;  3J7Z 1;  4A3F L;  5IYC L;  5MF6 A;  1ZRP A;  3LWV B;  2NVQ L;  2RDV A;  4G6B A;  2AYJ A;  1B71 A;  3FKI L;  2XJR A;  3FDJ A;  2E2J L;  4C3I L;  3B08 B;  3P2A A;  4WFN 1;  1PFW A;  2KN9 A;  1BFY A;  4B8C D;  4A3B L;  1IRO A;  1ODH A;  2V0F A;  5AI2 A;  3LWO B;  1YUZ A;  4AR3 A;  4RXN A;  2JA8 L;  3WWL A;  1SMM A;  4AHY A;  1VCX A;  4ZN1 B;  4AI3 A;  1OWC A;  3GTJ L;  1R9T L;  5IP7 L;  3GTP L;  4BY7 L;  5DM7 1;  4V19 6;  4LHN A;  3RZ6 A;  1RWD A;  2O5J D;  1YK5 A;  1PFY A;  1PFU A;  1S2Z A;  1TWC L;  3PKI A;  4YWM A;  4AI2 A;  3H3V M;  1T9Q A;  3LWR B;  2BE5 D;  2XJT A;  2WB1 P;  1P7P A;  3S2H L;  4XGH A;  4A3J L;  2R7Z L;  3H9B A;  1JYB A;  1I6H L;  2NVY L;  2NVX L;  3P8B A;  1NXE A;  4Y7N L;  1H7V A;  4X6A L;  2JA6 L;  3LNL A;  3A44 A;  1SFO L;  1YK4 A;  3HAX C;  4ME3 A;  5JVG 1;  3KYY A;  4TPU A;  1SMW A;  2QL0 A;  5MFZ A;  1WJV A;  3JR7 A;  5H1S c;  1BRF A;  3PWF A;  1IRN A;  1VZI A;  5MFP A;  2DSX A;  4QIW P;  4AR4 A;  2HVY C;  3PO2 L;  1LKM A;  3I4N L;  3QVD A;  4TVM A;  4AHW A;  1B2O A;  3SS2 A;  2V3B B;  2YU9 L;  3MQK B;  2A6E D;  4AR6 A;  4A93 L;  3LWQ B;  1B13 A;  2E2H L;  2PPT A;  3GTL L;  3RZO L;  3S14 L;  1FHH A;  5GAG c;  4AI1 A;  3HOY L;  4Y52 L;  5EIN C;  4BXX L;  2ERS A;  3S1Q L;  2APO B;  1I50 L;  3H0G L;  1TWG L;  3K7A L;  1IU5 A;  1TWH L;  1CAA A;  3S1M L;  1Z92 B;  3S16 L;  5GAH c;  2NYD A;  2ZIX A;  4JAE A;  2L0Z A;  1VZG A;  2R93 L;  5M3M L;  2M6P A;  4AYB P;  3HOV L;  4JAG A;  5C3E L;  3PIO 1;  2A69 D;  4AI0 A;  5MGN A;  1NNQ A;  1TWA L;  3S2D L;  3B0A B;  1LKP A;  2C6A A;  4BBS L;  3HOU L;  1NXG A;  3NFP I;  4XXB B;  5M5W L;  2XJU A;  4C2M 1;  2Z3R B;  2H12 A;  2PVE A;  2M4Y A;  1T9P A;  5K2M E;  1Y1V L;  2C6B A;  2JI1 A;  1OWB A;  3ZG6 A; 
#chains in the Genus database with same CATH homology
 3FKI L;  2JA7 L;  2E2J L;  4C3H L;  4C3I L;  4A3D L;  4QIW P;  5C44 L;  5C4X L;  5IYD L;  3GTM L;  3HKZ P;  3PO2 L;  3I4N L;  3M3Y L;  5M3F L;  4A3B L;  2JA5 L;  3GTG L;  3RZD L;  4A3K L;  3PO3 L;  1TWF L;  3M4O L;  4A3L L;  3I4M L;  5C4J L;  2JA8 L;  2YU9 L;  5IP9 L;  3S15 L;  3HOW L;  4A3I L;  5FLM L;  3GTJ L;  1R9T L;  4A93 L;  5IP7 L;  3GTP L;  5IYB L;  4BY7 L;  2E2H L;  1K83 L;  3GTL L;  4BBR L;  2NVT L;  3S14 L;  4C3J L;  2WAQ P;  3RZO L;  1WCM L;  4A3E L;  2R92 L;  4A3G L;  3HOY L;  4Y52 L;  4BXX L;  2B63 L;  1TWC L;  3S1Q L;  1I50 L;  2VUM L;  3GTK L;  3H0G L;  3H3V M;  1TWG L;  3K7A L;  3S1N L;  1TWH L;  3GTO L;  3S1M L;  2WB1 P;  2PMZ P;  3S16 L;  3S2H L;  3S17 L;  4A3J L;  2R7Z L;  5M5Y L;  2R93 L;  5M3M L;  5M5X L;  1I6H L;  2NVY L;  4AYB P;  2NVX L;  3HOV L;  3HOZ L;  4BY1 L;  5C3E L;  2E2I L;  1I3Q L;  4Y7N L;  4A3C L;  3HOX L;  4X6A L;  2JA6 L;  1SFO L;  1TWA L;  3S2D L;  3GTQ L;  4BBS L;  3HOU L;  4A3M L;  5M5W L;  4C2M 1;  5FJ8 L;  3S1R L;  1Y1W L;  3CQZ L;  1Y1V L;  2Y0S P;  4A3F L;  5IYC L;  2NVQ L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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