5C4XL

Crystal structure of a transcribing rna polymerase ii complex reveals a complete transcription bubble
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
44
structure length
44
Chain Sequence
LKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/rna/dna
source organism Saccharomyces cerevisiae (strain atcc 204508 / s288c)
publication title Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
pubmed doi rcsb
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 3
structure length 44
sequence length 44
ec nomenclature
pdb deposition date 2015-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 5c4xL00
1Y1VL 4BY1L 3HOVL 3M4OL 3RZOL 4A3EL 1I50L 2NVYL 2JA5L 2JA8L 3I4ML 1I6HL 3I4NL 1TWFL 5M5YL 4C3IL 3H0GL 4BXXL 4BY7L 3GTQL 4A3BL 4A3ML 1WCML 2NVXL 3FKIL 4A3FL 3S14L 5M3ML 1TWCL 3GTML 3CQZL 5C4JL 4C2M1 2VUML 3RZDL 3PO3L 3PO2L 3GTLL 3K7AL 3GTGL 5C4XL 2R93L 5IYCL 3HOZL 1Y1WL 4BBSL 2R7ZL 2WB1P 5IP9L 4BBRL 5C3EL 2JA7L 4A3LL 4AYBP 4A3GL 2Y0SP 3GTKL 5IYDL 3GTOL 1TWHL 4A3JL 3HOUL 4Y7NL 4C3HL 4X6AL 3GTPL 3S17L 3S2HL 1K83L 3S1RL 2E2IL 5M5WL 3S1ML 3S1NL 4A3CL 3S2DL 5M3FL 5IP7L 3HOWL 5FLML 3GTJL 5C44L 4Y52L 4A3IL 4A93L 2NVQL 1I3QL 2WAQP 5IYBL 3HKZP 3HOXL 2E2HL 1R9TL 2YU9L 1TWGL 2E2JL 4C3JL 2JA6L 3HOYL 4A3DL 3S1QL 5M5XL 2PMZP 3S15L 2B63L 4QIWP 1SFOL 3H3VM 2R92L 2NVTL 3S16L 1TWAL 3M3YL 4A3KL 5FJ8L
chains in the Genus database with same CATH superfamily
2AQCA 2NVYL 5JVH1 5GAHc 2JA8L 1DVBA 4AR5A 2Z3RB 2CKCA 3P2AA 1TWFL 3LPEB 5M5YL 4UY81 4JAFA 4A3ML 2APOB 1PFWA 5GADc 1TWCL 1LKMA 4WFN1 1IRNA 3LWPB 3GTML 3LNLA 1R0FA 2PSMC 5C4JL 4C2M1 1BRFA 2VUML 3B08B 3LWOB 3H97A 2R93L 1YK5A 1PFVA 4AR3A 2HR5A 4E6YA 4JAGA 4JADA 5MFZA 3PKIA 2JI3A 1R0JA 2JA7L 4A3LL 7RXNA 1E8JA 3H99A 2C6BA 5MF6A 2H12A 1VZGA 5DM61 1CAAA 2Z3QB 3GTOL 3QQCE 4Y7NL 1YK4A 4C3HL 2PVEA 2E2IL 2DSXA 1FHMA 3HAXC 2RDVA 5JVG1 5C44L 4Y52L 4AR4A 1BFYA 2NVQL 3WWNB 2J9UB 3IU3I 1I3QL 2WAQP 3HKZP 3HOXL 1B2JA 3QVDA 2E2JL 2JA6L 4AR6A 4ME3A 5AN9H 3KYVA 2KN9A 3PIP1 4B8CD 1CADA 3M3YL 1QYBA 1Y1VL 3ZG6A 1OWCA 3KYUA 1VZHA 2JA5L 2PYAA 2XJRA 1I6HL 1QQTA 4AHZA 4C3IL 4BXXL 3LWQB 1B13A 2NVXL 5MFPA 2A69D 1OWBA 5M3ML 5MGNA 2ERJA 1YUZA 3CQZL 4POFA 3RZDL 3B0AB 1R0GA 3GTLL 5IY0A 2AUSB 3GTGL 1S2ZA 1PFUA 5AI2A 2CR8A 2R7ZL 1LTLA 3PWFA 4BBRL 1R0IA 2JI2A 1WJVA 6RXNA 2QL0A 2Y0SP 1F4LA 3FDJA 1H7VA 1T9OA 2XJQA 1R0HA 1LKPA 5H1Sc 3S1RL 5M5WL 2A6HD 4A3CL 3RZ6A 5IP7L 3VPBE 1YUXA 3HOWL 3PIO1 2CKAA 4A3IL 1C09A 1FHHA 2V3BB 1IU5A 5AI3A 1R9TL 1SMWA 4C3JL 2RFKB 2C6AA 1B71A 1SFOL 2R92L 2NVTL 3RZTA 1TWAL 1DX8A 1LKOA 2M4VA 4BY1L 1IROA 2VL6A 1RWDA 3RZOL 4A3EL 2KKDA 3H9BA 1I50L 2K2DA 2XJVA 2LCQA 4ZN3B 4AHXA 3I4NL 4XGHA 3H0GL 4BY7L 1VCXA 4GS7D 4JAEA 1WCML 3FKIL 5EIOC 2HVYC 2EY4E 2GMGA 3LWRB 4AHWA 3PO2L 1SMMA 4YWLA 2ZIXA 4TPUA 1VZIA 5IYCL 1BQ8A 3H9CA 2V0FA 1PZXA 4BBSL 2XJUA 2BE5D 2O5JD 5IP9L 2PPTA 1ODHA 4AYBP 5RXNA 1NXEA 3KYWA 4A3GL 1IW7D 4YWMA 3GTKL 2V0EA 5IYDL 4A3JL 3HOUL 4X6AL 3GTPL 1K83L 3KYYA 4ZN1B 2M6PA 1RYTA 3S2DL 5FLML 5GAGc 3GTJL 1RB9A 3JR7A 1RDVA 2XJSA 5IYBL 2E2HL 2XJPA 1TWGL 2M6OA 3HJWB 3HOYL 4XXBB 2PMZP 4RXNA 4QIWP 1S30A 8RXNA 4LHLA 3WWLA 3S16L 1T9PA 2L0ZA 4U671 5FJ8L 2M4YA 1T9QA 3HOVL 3A44A 3M4OL 3MPSA 1QCVA 1SMUA 5K2ME 1S24A 3I4ML 2PVXA 3J7Z1 2A6ED 5MLC3 3GTQL 3PL5A 4A3BL 4V196 4K9FA 3SS2A 2B5ID 1JYBA 4A3FL 4AHYA 5DM71 3S14L 2A68D 3MSUA 2XJTA 4POGA 3PO3L 1Z92B 4AI3A 3K7AL 1PFYA 5C4XL 1BQ9A 4G6BA 3PKJA 1YV1A 1ZRPA 3HOZL 3HJYB 1Y1WL 4TVMA 1RYQA 5GAEc 2WB1P 5C3EL 4AI1A 3NFPI 1RDGA 1NXGA 3LWVB 5EINC 1TWHL 3K35A 3S2HL 3S17L 2AYJA 1B2OA 3MQKB 3S1ML 1BE7A 1IU6A 3S1NL 5M3FL 1P7PA 2ERSA 4LHNA 3P8BA 4A93L 3RYGA 2YU9L 3PZAA 2MS3A 4A3DL 3S1QL 5M5XL 3S15L 2B63L 2NYDA 3KYXA 3H3VM 3J7Y1 1NNQA 4AI0A 2JI1A 4A3KL 4AI2A
chains in the Genus database with same CATH topology
1Y1VL 4BY1L 3HOVL 3M4OL 3RZOL 4A3EL 1I50L 2NVYL 2JA5L 2JA8L 3I4ML 1I6HL 3I4NL 1TWFL 5M5YL 4C3IL 3H0GL 4BXXL 4BY7L 3GTQL 4A3BL 4A3ML 1WCML 2NVXL 3FKIL 4A3FL 3S14L 5M3ML 1TWCL 3GTML 3CQZL 5C4JL 4C2M1 2VUML 3RZDL 3PO3L 3PO2L 3GTLL 3K7AL 3GTGL 5C4XL 2R93L 5IYCL 3HOZL 1Y1WL 4BBSL 2R7ZL 2WB1P 5IP9L 4BBRL 5C3EL 2JA7L 4A3LL 4AYBP 4A3GL 2Y0SP 3GTKL 5IYDL 3GTOL 1TWHL 4A3JL 3HOUL 4Y7NL 4C3HL 4X6AL 3GTPL 3S17L 3S2HL 1K83L 3S1RL 2E2IL 5M5WL 3S1ML 3S1NL 4A3CL 3S2DL 5M3FL 5IP7L 3HOWL 5FLML 3GTJL 5C44L 4Y52L 4A3IL 4A93L 2NVQL 1I3QL 2WAQP 5IYBL 3HKZP 3HOXL 2E2HL 1R9TL 2YU9L 1TWGL 2E2JL 4C3JL 2JA6L 3HOYL 4A3DL 3S1QL 5M5XL 2PMZP 3S15L 2B63L 4QIWP 1SFOL 3H3VM 2R92L 2NVTL 3S16L 1TWAL 3M3YL 4A3KL 5FJ8L
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Y1V L;  4BY1 L;  3HOV L;  3M4O L;  3RZO L;  4A3E L;  1I50 L;  2NVY L;  2JA5 L;  2JA8 L;  3I4M L;  1I6H L;  3I4N L;  1TWF L;  5M5Y L;  4C3I L;  3H0G L;  4BXX L;  4BY7 L;  3GTQ L;  4A3B L;  4A3M L;  1WCM L;  2NVX L;  3FKI L;  4A3F L;  3S14 L;  5M3M L;  1TWC L;  3GTM L;  3CQZ L;  5C4J L;  4C2M 1;  2VUM L;  3RZD L;  3PO3 L;  3PO2 L;  3GTL L;  3K7A L;  3GTG L;  5C4X L;  2R93 L;  5IYC L;  3HOZ L;  1Y1W L;  4BBS L;  2R7Z L;  2WB1 P;  5IP9 L;  4BBR L;  5C3E L;  2JA7 L;  4A3L L;  4AYB P;  4A3G L;  2Y0S P;  3GTK L;  5IYD L;  3GTO L;  1TWH L;  4A3J L;  3HOU L;  4Y7N L;  4C3H L;  4X6A L;  3GTP L;  3S17 L;  3S2H L;  1K83 L;  3S1R L;  2E2I L;  5M5W L;  3S1M L;  3S1N L;  4A3C L;  3S2D L;  5M3F L;  5IP7 L;  3HOW L;  5FLM L;  3GTJ L;  5C44 L;  4Y52 L;  4A3I L;  4A93 L;  2NVQ L;  1I3Q L;  2WAQ P;  5IYB L;  3HKZ P;  3HOX L;  2E2H L;  1R9T L;  2YU9 L;  1TWG L;  2E2J L;  4C3J L;  2JA6 L;  3HOY L;  4A3D L;  3S1Q L;  5M5X L;  2PMZ P;  3S15 L;  2B63 L;  4QIW P;  1SFO L;  3H3V M;  2R92 L;  2NVT L;  3S16 L;  1TWA L;  3M3Y L;  4A3K L;  5FJ8 L; 
#chains in the Genus database with same CATH topology
 2AQC A;  2NVY L;  5JVH 1;  5GAH c;  2JA8 L;  1DVB A;  4AR5 A;  2Z3R B;  2CKC A;  3P2A A;  1TWF L;  3LPE B;  5M5Y L;  4UY8 1;  4JAF A;  4A3M L;  2APO B;  1PFW A;  5GAD c;  1TWC L;  1LKM A;  4WFN 1;  1IRN A;  3LWP B;  3GTM L;  3LNL A;  1R0F A;  2PSM C;  5C4J L;  4C2M 1;  1BRF A;  2VUM L;  3B08 B;  3LWO B;  3H97 A;  2R93 L;  1YK5 A;  1PFV A;  4AR3 A;  2HR5 A;  4E6Y A;  4JAG A;  4JAD A;  5MFZ A;  3PKI A;  2JI3 A;  1R0J A;  2JA7 L;  4A3L L;  7RXN A;  1E8J A;  3H99 A;  2C6B A;  5MF6 A;  2H12 A;  1VZG A;  5DM6 1;  1CAA A;  2Z3Q B;  3GTO L;  3QQC E;  4Y7N L;  1YK4 A;  4C3H L;  2PVE A;  2E2I L;  2DSX A;  1FHM A;  3HAX C;  2RDV A;  5JVG 1;  5C44 L;  4Y52 L;  4AR4 A;  1BFY A;  2NVQ L;  3WWN B;  2J9U B;  3IU3 I;  1I3Q L;  2WAQ P;  3HKZ P;  3HOX L;  1B2J A;  3QVD A;  2E2J L;  2JA6 L;  4AR6 A;  4ME3 A;  5AN9 H;  3KYV A;  2KN9 A;  3PIP 1;  4B8C D;  1CAD A;  3M3Y L;  1QYB A;  1Y1V L;  3ZG6 A;  1OWC A;  3KYU A;  1VZH A;  2JA5 L;  2PYA A;  2XJR A;  1I6H L;  1QQT A;  4AHZ A;  4C3I L;  4BXX L;  3LWQ B;  1B13 A;  2NVX L;  5MFP A;  2A69 D;  1OWB A;  5M3M L;  5MGN A;  2ERJ A;  1YUZ A;  3CQZ L;  4POF A;  3RZD L;  3B0A B;  1R0G A;  3GTL L;  5IY0 A;  2AUS B;  3GTG L;  1S2Z A;  1PFU A;  5AI2 A;  2CR8 A;  2R7Z L;  1LTL A;  3PWF A;  4BBR L;  1R0I A;  2JI2 A;  1WJV A;  6RXN A;  2QL0 A;  2Y0S P;  1F4L A;  3FDJ A;  1H7V A;  1T9O A;  2XJQ A;  1R0H A;  1LKP A;  5H1S c;  3S1R L;  5M5W L;  2A6H D;  4A3C L;  3RZ6 A;  5IP7 L;  3VPB E;  1YUX A;  3HOW L;  3PIO 1;  2CKA A;  4A3I L;  1C09 A;  1FHH A;  2V3B B;  1IU5 A;  5AI3 A;  1R9T L;  1SMW A;  4C3J L;  2RFK B;  2C6A A;  1B71 A;  1SFO L;  2R92 L;  2NVT L;  3RZT A;  1TWA L;  1DX8 A;  1LKO A;  2M4V A;  4BY1 L;  1IRO A;  2VL6 A;  1RWD A;  3RZO L;  4A3E L;  2KKD A;  3H9B A;  1I50 L;  2K2D A;  2XJV A;  2LCQ A;  4ZN3 B;  4AHX A;  3I4N L;  4XGH A;  3H0G L;  4BY7 L;  1VCX A;  4GS7 D;  4JAE A;  1WCM L;  3FKI L;  5EIO C;  2HVY C;  2EY4 E;  2GMG A;  3LWR B;  4AHW A;  3PO2 L;  1SMM A;  4YWL A;  2ZIX A;  4TPU A;  1VZI A;  5IYC L;  1BQ8 A;  3H9C A;  2V0F A;  1PZX A;  4BBS L;  2XJU A;  2BE5 D;  2O5J D;  5IP9 L;  2PPT A;  1ODH A;  4AYB P;  5RXN A;  1NXE A;  3KYW A;  4A3G L;  1IW7 D;  4YWM A;  3GTK L;  2V0E A;  5IYD L;  4A3J L;  3HOU L;  4X6A L;  3GTP L;  1K83 L;  3KYY A;  4ZN1 B;  2M6P A;  1RYT A;  3S2D L;  5FLM L;  5GAG c;  3GTJ L;  1RB9 A;  3JR7 A;  1RDV A;  2XJS A;  5IYB L;  2E2H L;  2XJP A;  1TWG L;  2M6O A;  3HJW B;  3HOY L;  4XXB B;  2PMZ P;  4RXN A;  4QIW P;  1S30 A;  8RXN A;  4LHL A;  3WWL A;  3S16 L;  1T9P A;  2L0Z A;  4U67 1;  5FJ8 L;  2M4Y A;  1T9Q A;  3HOV L;  3A44 A;  3M4O L;  3MPS A;  1QCV A;  1SMU A;  5K2M E;  1S24 A;  3I4M L;  2PVX A;  3J7Z 1;  2A6E D;  5MLC 3;  3GTQ L;  3PL5 A;  4A3B L;  4V19 6;  4K9F A;  3SS2 A;  2B5I D;  1JYB A;  4A3F L;  4AHY A;  5DM7 1;  3S14 L;  2A68 D;  3MSU A;  2XJT A;  4POG A;  3PO3 L;  1Z92 B;  4AI3 A;  3K7A L;  1PFY A;  5C4X L;  1BQ9 A;  4G6B A;  3PKJ A;  1YV1 A;  1ZRP A;  3HOZ L;  3HJY B;  1Y1W L;  4TVM A;  1RYQ A;  5GAE c;  2WB1 P;  5C3E L;  4AI1 A;  3NFP I;  1RDG A;  1NXG A;  3LWV B;  5EIN C;  1TWH L;  3K35 A;  3S2H L;  3S17 L;  2AYJ A;  1B2O A;  3MQK B;  3S1M L;  1BE7 A;  1IU6 A;  3S1N L;  5M3F L;  1P7P A;  2ERS A;  4LHN A;  3P8B A;  4A93 L;  3RYG A;  2YU9 L;  3PZA A;  2MS3 A;  4A3D L;  3S1Q L;  5M5X L;  3S15 L;  2B63 L;  2NYD A;  3KYX A;  3H3V M;  3J7Y 1;  1NNQ A;  4AI0 A;  2JI1 A;  4A3K L;  4AI2 A; 
#chains in the Genus database with same CATH homology
 1Y1V L;  4BY1 L;  3HOV L;  3M4O L;  3RZO L;  4A3E L;  1I50 L;  2NVY L;  2JA5 L;  2JA8 L;  3I4M L;  1I6H L;  3I4N L;  1TWF L;  5M5Y L;  4C3I L;  3H0G L;  4BXX L;  4BY7 L;  3GTQ L;  4A3B L;  4A3M L;  1WCM L;  2NVX L;  3FKI L;  4A3F L;  3S14 L;  5M3M L;  1TWC L;  3GTM L;  3CQZ L;  5C4J L;  4C2M 1;  2VUM L;  3RZD L;  3PO3 L;  3PO2 L;  3GTL L;  3K7A L;  3GTG L;  5C4X L;  2R93 L;  5IYC L;  3HOZ L;  1Y1W L;  4BBS L;  2R7Z L;  2WB1 P;  5IP9 L;  4BBR L;  5C3E L;  2JA7 L;  4A3L L;  4AYB P;  4A3G L;  2Y0S P;  3GTK L;  5IYD L;  3GTO L;  1TWH L;  4A3J L;  3HOU L;  4Y7N L;  4C3H L;  4X6A L;  3GTP L;  3S17 L;  3S2H L;  1K83 L;  3S1R L;  2E2I L;  5M5W L;  3S1M L;  3S1N L;  4A3C L;  3S2D L;  5M3F L;  5IP7 L;  3HOW L;  5FLM L;  3GTJ L;  5C44 L;  4Y52 L;  4A3I L;  4A93 L;  2NVQ L;  1I3Q L;  2WAQ P;  5IYB L;  3HKZ P;  3HOX L;  2E2H L;  1R9T L;  2YU9 L;  1TWG L;  2E2J L;  4C3J L;  2JA6 L;  3HOY L;  4A3D L;  3S1Q L;  5M5X L;  2PMZ P;  3S15 L;  2B63 L;  4QIW P;  1SFO L;  3H3V M;  2R92 L;  2NVT L;  3S16 L;  1TWA L;  3M3Y L;  4A3K L;  5FJ8 L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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