5C4XL

Crystal structure of a transcribing rna polymerase ii complex reveals a complete transcription bubble
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
44
structure length
44
Chain Sequence
LKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
pubmed doi rcsb
molecule tags Transferase/rna/dna
source organism Saccharomyces cerevisiae (strain atcc 204508 / s288c)
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 3
structure length 44
sequence length 44
ec nomenclature
pdb deposition date 2015-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 5c4xL00
3GTJL 5IYBL 3GTKL 2WB1P 2R7ZL 4QIWP 2NVTL 3FKIL 4BBSL 3S2HL 4A3KL 3HOYL 4A3GL 5M3ML 2R92L 4BXXL 3S2DL 5M5WL 5FJ8L 4Y7NL 3K7AL 5IP9L 3GTML 3S1QL 4C3JL 2PMZP 3CQZL 1TWCL 4A3IL 5C4XL 1WCML 1TWAL 3S15L 4BBRL 2E2HL 3M4OL 5C3EL 1Y1WL 3HOVL 2NVXL 5IYDL 4A3EL 3RZDL 5M3FL 3S14L 3HOZL 1R9TL 1SFOL 4C3HL 4A3ML 3S1ML 2JA6L 1TWHL 3GTOL 5IP7L 2NVQL 4X6AL 2NVYL 2E2IL 5C4JL 3HOXL 2B63L 4BY7L 3M3YL 2R93L 4C2M1 1TWFL 3HOWL 2VUML 3I4NL 2JA7L 4A3FL 5M5XL 2Y0SP 1Y1VL 3S1RL 2JA8L 5C44L 4AYBP 3GTQL 4A3JL 3GTPL 5M5YL 4A3LL 3HOUL 4Y52L 2E2JL 3RZOL 1K83L 4C3IL 1TWGL 1I3QL 1I50L 4A3CL 3HKZP 2JA5L 4A3DL 3S1NL 3H3VM 3S17L 4BY1L 2WAQP 3GTLL 3I4ML 5IYCL 4A3BL 1I6HL 3GTGL 4A93L 3H0GL 5FLML 3S16L 3PO3L 3PO2L 2YU9L
chains in the Genus database with same CATH superfamily
2Z3QB 2Z3RB 5IYBL 2WB1P 3A44A 3ZG6A 2NVTL 3FKIL 1VZHA 4A3KL 3LPEB 5M3ML 3LNLA 3MQKB 1YUXA 1QQTA 2V3BB 5FJ8L 3LWOB 5IP9L 4E6YA 1IW7D 3LWPB 4A3IL 5C4XL 5AI2A 3S15L 1B13A 1E8JA 5JVG1 2CKCA 3M4OL 1LKPA 5C3EL 3QQCE 4YWMA 5IYDL 3JR7A 4U671 5M3FL 3RZDL 5MLC3 5DM61 3WWNB 4JAFA 1PFWA 1TWHL 2PSMC 3H9BA 2XJQA 1R0GA 1YV1A 3H9CA 2GMGA 3M3YL 4AR6A 1R0HA 4C2M1 2L0ZA 5RXNA 4XXBB 5EINC 5JVH1 4AHZA 1S2ZA 8RXNA 5GADc 3GTQL 3GTPL 1LTLA 3LWQB 2E2JL 2XJPA 4AR3A 3PZAA 1I50L 1DX8A 3HKZP 4A3DL 3H3VM 4BY1L 2WAQP 1BQ8A 1QCVA 2MS3A 5FLML 4AR5A 3S16L 2YU9L 2PVEA 2XJUA 3B08B 1BQ9A 3P2AA 3GTJL 2JI3A 2HVYC 3GTKL 2BE5D 2R7ZL 4QIWP 1OWCA 1BFYA 3S2HL 4A3GL 1RYQA 2QL0A 2R92L 4LHLA 2C6AA 1IU5A 2A6HD 5M5WL 4Y7NL 1DVBA 3GTML 4C3JL 1WJVA 2M4VA 4AI0A 3PKIA 2AQCA 4YWLA 5MF6A 2NVXL 3P8BA 3IU3I 2ERJA 3HOZL 1R9TL 1SFOL 3QVDA 3RZ6A 1H7VA 3B0AB 1IU6A 5GAGc 2NVQL 4TPUA 3LWRB 2EY4E 2A68D 4JAEA 3H99A 4BY7L 2VUML 4AI3A 2Y0SP 1BRFA 5DM71 3S1RL 2JA8L 2VL6A 2JI2A 4AYBP 5M5YL 4Y52L 1T9OA 3PIO1 5AI3A 3RZOL 4C3IL 7RXNA 1TWGL 1LKOA 1C09A 3FDJA 3S17L 1VZGA 5EIOC 2KN9A 2RFKB 3I4ML 4A3BL 1ZRPA 1I6HL 3LWVB 2CKAA 2M4YA 3H0GL 3PO3L 3PO2L 1F4LA 3KYUA 4UY81 1YK4A 2XJRA 3KYYA 2XJSA 1VZIA 1SMWA 3VPBE 4ME3A 2M6PA 2DSXA 3HJWB 4BXXL 2KKDA 2APOB 3S1QL 1IRNA 1TWCL 3NFPI 3KYXA 1WCML 1TWAL 4BBRL 4POFA 4K9FA 4POGA 2M6OA 1B2OA 4ZN3B 1Y1WL 2B5ID 3HOVL 3J7Y1 4AR4A 4TVMA 1YK5A 1CAAA 1SMMA 1YUZA 4C3HL 2ZIXA 2AUSB 2K2DA 1RYTA 2JA6L 5GAHc 5IP7L 3RYGA 2C6BA 1PFVA 1NXGA 5H1Sc 2NVYL 5C4JL 2A69D 1FHHA 5K2ME 1R0IA 4RXNA 1TWFL 3HOWL 1CADA 1T9PA 2JA7L 4A3FL 5GAEc 3KYWA 1S30A 5C44L 1S24A 4A3LL 1LKMA 2JI1A 2NYDA 1OWBA 4JAGA 1K83L 3HAXC 2V0EA 3WWLA 2V0FA 3J7Z1 2J9UB 3GTLL 5IYCL 3SS2A 4G6BA 2PVXA 3GTGL 4A93L 1BE7A 1R0FA 1PZXA 4AHWA 4AI1A 2XJTA 3KYVA 1JYBA 2PPTA 3PL5A 4LHNA 2XJVA 3HJYB 1B71A 4BBSL 3HOYL 1Z92B 3MSUA 1IROA 4GS7D 4ZN1B 1QYBA 3S2DL 1RWDA 3K7AL 4JADA 5AN9H 2PMZP 3CQZL 1R0JA 2AYJA 3H97A 5MFPA 1B2JA 1RDGA 5MGNA 2E2HL 1NXEA 1P7PA 4A3EL 2RDVA 3S14L 3PIP1 4A3ML 3S1ML 1SMUA 1FHMA 4AI2A 3GTOL 3RZTA 4X6AL 2E2IL 3HOXL 2B63L 1RDVA 2ERSA 2O5JD 1PFUA 2R93L 3I4NL 4AHYA 5M5XL 5MFZA 1Y1VL 4AHXA 3PWFA 1NNQA 4V196 1PFYA 5IY0A 4A3JL 3PKJA 4B8CD 3HOUL 6RXNA 2H12A 4WFN1 1ODHA 4XGHA 2LCQA 2CR8A 1I3QL 1T9QA 1VCXA 2PYAA 4A3CL 2JA5L 3S1NL 1RB9A 2A6ED 2HR5A 3MPSA 3K35A
chains in the Genus database with same CATH topology
3GTJL 5IYBL 3GTKL 2WB1P 2R7ZL 4QIWP 2NVTL 3FKIL 4BBSL 3S2HL 4A3KL 3HOYL 4A3GL 5M3ML 2R92L 4BXXL 3S2DL 5M5WL 5FJ8L 4Y7NL 3K7AL 5IP9L 3GTML 3S1QL 4C3JL 2PMZP 3CQZL 1TWCL 4A3IL 5C4XL 1WCML 1TWAL 3S15L 4BBRL 2E2HL 3M4OL 5C3EL 1Y1WL 3HOVL 2NVXL 5IYDL 4A3EL 3RZDL 5M3FL 3S14L 3HOZL 1R9TL 1SFOL 4C3HL 4A3ML 3S1ML 2JA6L 1TWHL 3GTOL 5IP7L 2NVQL 4X6AL 2NVYL 2E2IL 5C4JL 3HOXL 2B63L 4BY7L 3M3YL 2R93L 4C2M1 1TWFL 3HOWL 2VUML 3I4NL 2JA7L 4A3FL 5M5XL 2Y0SP 1Y1VL 3S1RL 2JA8L 5C44L 4AYBP 3GTQL 4A3JL 3GTPL 5M5YL 4A3LL 3HOUL 4Y52L 2E2JL 3RZOL 1K83L 4C3IL 1TWGL 1I3QL 1I50L 4A3CL 3HKZP 2JA5L 4A3DL 3S1NL 3H3VM 3S17L 4BY1L 2WAQP 3GTLL 3I4ML 5IYCL 4A3BL 1I6HL 3GTGL 4A93L 3H0GL 5FLML 3S16L 3PO3L 3PO2L 2YU9L
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GTJ L;  5IYB L;  3GTK L;  2WB1 P;  2R7Z L;  4QIW P;  2NVT L;  3FKI L;  4BBS L;  3S2H L;  4A3K L;  3HOY L;  4A3G L;  5M3M L;  2R92 L;  4BXX L;  3S2D L;  5M5W L;  5FJ8 L;  4Y7N L;  3K7A L;  5IP9 L;  3GTM L;  3S1Q L;  4C3J L;  2PMZ P;  3CQZ L;  1TWC L;  4A3I L;  5C4X L;  1WCM L;  1TWA L;  3S15 L;  4BBR L;  2E2H L;  3M4O L;  5C3E L;  1Y1W L;  3HOV L;  2NVX L;  5IYD L;  4A3E L;  3RZD L;  5M3F L;  3S14 L;  3HOZ L;  1R9T L;  1SFO L;  4C3H L;  4A3M L;  3S1M L;  2JA6 L;  1TWH L;  3GTO L;  5IP7 L;  2NVQ L;  4X6A L;  2NVY L;  2E2I L;  5C4J L;  3HOX L;  2B63 L;  4BY7 L;  3M3Y L;  2R93 L;  4C2M 1;  1TWF L;  3HOW L;  2VUM L;  3I4N L;  2JA7 L;  4A3F L;  5M5X L;  2Y0S P;  1Y1V L;  3S1R L;  2JA8 L;  5C44 L;  4AYB P;  3GTQ L;  4A3J L;  3GTP L;  5M5Y L;  4A3L L;  3HOU L;  4Y52 L;  2E2J L;  3RZO L;  1K83 L;  4C3I L;  1TWG L;  1I3Q L;  1I50 L;  4A3C L;  3HKZ P;  2JA5 L;  4A3D L;  3S1N L;  3H3V M;  3S17 L;  4BY1 L;  2WAQ P;  3GTL L;  3I4M L;  5IYC L;  4A3B L;  1I6H L;  3GTG L;  4A93 L;  3H0G L;  5FLM L;  3S16 L;  3PO3 L;  3PO2 L;  2YU9 L; 
#chains in the Genus database with same CATH topology
 2Z3Q B;  2Z3R B;  5IYB L;  2WB1 P;  3A44 A;  3ZG6 A;  2NVT L;  3FKI L;  1VZH A;  4A3K L;  3LPE B;  5M3M L;  3LNL A;  3MQK B;  1YUX A;  1QQT A;  2V3B B;  5FJ8 L;  3LWO B;  5IP9 L;  4E6Y A;  1IW7 D;  3LWP B;  4A3I L;  5C4X L;  5AI2 A;  3S15 L;  1B13 A;  1E8J A;  5JVG 1;  2CKC A;  3M4O L;  1LKP A;  5C3E L;  3QQC E;  4YWM A;  5IYD L;  3JR7 A;  4U67 1;  5M3F L;  3RZD L;  5MLC 3;  5DM6 1;  3WWN B;  4JAF A;  1PFW A;  1TWH L;  2PSM C;  3H9B A;  2XJQ A;  1R0G A;  1YV1 A;  3H9C A;  2GMG A;  3M3Y L;  4AR6 A;  1R0H A;  4C2M 1;  2L0Z A;  5RXN A;  4XXB B;  5EIN C;  5JVH 1;  4AHZ A;  1S2Z A;  8RXN A;  5GAD c;  3GTQ L;  3GTP L;  1LTL A;  3LWQ B;  2E2J L;  2XJP A;  4AR3 A;  3PZA A;  1I50 L;  1DX8 A;  3HKZ P;  4A3D L;  3H3V M;  4BY1 L;  2WAQ P;  1BQ8 A;  1QCV A;  2MS3 A;  5FLM L;  4AR5 A;  3S16 L;  2YU9 L;  2PVE A;  2XJU A;  3B08 B;  1BQ9 A;  3P2A A;  3GTJ L;  2JI3 A;  2HVY C;  3GTK L;  2BE5 D;  2R7Z L;  4QIW P;  1OWC A;  1BFY A;  3S2H L;  4A3G L;  1RYQ A;  2QL0 A;  2R92 L;  4LHL A;  2C6A A;  1IU5 A;  2A6H D;  5M5W L;  4Y7N L;  1DVB A;  3GTM L;  4C3J L;  1WJV A;  2M4V A;  4AI0 A;  3PKI A;  2AQC A;  4YWL A;  5MF6 A;  2NVX L;  3P8B A;  3IU3 I;  2ERJ A;  3HOZ L;  1R9T L;  1SFO L;  3QVD A;  3RZ6 A;  1H7V A;  3B0A B;  1IU6 A;  5GAG c;  2NVQ L;  4TPU A;  3LWR B;  2EY4 E;  2A68 D;  4JAE A;  3H99 A;  4BY7 L;  2VUM L;  4AI3 A;  2Y0S P;  1BRF A;  5DM7 1;  3S1R L;  2JA8 L;  2VL6 A;  2JI2 A;  4AYB P;  5M5Y L;  4Y52 L;  1T9O A;  3PIO 1;  5AI3 A;  3RZO L;  4C3I L;  7RXN A;  1TWG L;  1LKO A;  1C09 A;  3FDJ A;  3S17 L;  1VZG A;  5EIO C;  2KN9 A;  2RFK B;  3I4M L;  4A3B L;  1ZRP A;  1I6H L;  3LWV B;  2CKA A;  2M4Y A;  3H0G L;  3PO3 L;  3PO2 L;  1F4L A;  3KYU A;  4UY8 1;  1YK4 A;  2XJR A;  3KYY A;  2XJS A;  1VZI A;  1SMW A;  3VPB E;  4ME3 A;  2M6P A;  2DSX A;  3HJW B;  4BXX L;  2KKD A;  2APO B;  3S1Q L;  1IRN A;  1TWC L;  3NFP I;  3KYX A;  1WCM L;  1TWA L;  4BBR L;  4POF A;  4K9F A;  4POG A;  2M6O A;  1B2O A;  4ZN3 B;  1Y1W L;  2B5I D;  3HOV L;  3J7Y 1;  4AR4 A;  4TVM A;  1YK5 A;  1CAA A;  1SMM A;  1YUZ A;  4C3H L;  2ZIX A;  2AUS B;  2K2D A;  1RYT A;  2JA6 L;  5GAH c;  5IP7 L;  3RYG A;  2C6B A;  1PFV A;  1NXG A;  5H1S c;  2NVY L;  5C4J L;  2A69 D;  1FHH A;  5K2M E;  1R0I A;  4RXN A;  1TWF L;  3HOW L;  1CAD A;  1T9P A;  2JA7 L;  4A3F L;  5GAE c;  3KYW A;  1S30 A;  5C44 L;  1S24 A;  4A3L L;  1LKM A;  2JI1 A;  2NYD A;  1OWB A;  4JAG A;  1K83 L;  3HAX C;  2V0E A;  3WWL A;  2V0F A;  3J7Z 1;  2J9U B;  3GTL L;  5IYC L;  3SS2 A;  4G6B A;  2PVX A;  3GTG L;  4A93 L;  1BE7 A;  1R0F A;  1PZX A;  4AHW A;  4AI1 A;  2XJT A;  3KYV A;  1JYB A;  2PPT A;  3PL5 A;  4LHN A;  2XJV A;  3HJY B;  1B71 A;  4BBS L;  3HOY L;  1Z92 B;  3MSU A;  1IRO A;  4GS7 D;  4ZN1 B;  1QYB A;  3S2D L;  1RWD A;  3K7A L;  4JAD A;  5AN9 H;  2PMZ P;  3CQZ L;  1R0J A;  2AYJ A;  3H97 A;  5MFP A;  1B2J A;  1RDG A;  5MGN A;  2E2H L;  1NXE A;  1P7P A;  4A3E L;  2RDV A;  3S14 L;  3PIP 1;  4A3M L;  3S1M L;  1SMU A;  1FHM A;  4AI2 A;  3GTO L;  3RZT A;  4X6A L;  2E2I L;  3HOX L;  2B63 L;  1RDV A;  2ERS A;  2O5J D;  1PFU A;  2R93 L;  3I4N L;  4AHY A;  5M5X L;  5MFZ A;  1Y1V L;  4AHX A;  3PWF A;  1NNQ A;  4V19 6;  1PFY A;  5IY0 A;  4A3J L;  3PKJ A;  4B8C D;  3HOU L;  6RXN A;  2H12 A;  4WFN 1;  1ODH A;  4XGH A;  2LCQ A;  2CR8 A;  1I3Q L;  1T9Q A;  1VCX A;  2PYA A;  4A3C L;  2JA5 L;  3S1N L;  1RB9 A;  2A6E D;  2HR5 A;  3MPS A;  3K35 A; 
#chains in the Genus database with same CATH homology
 3GTJ L;  5IYB L;  3GTK L;  2WB1 P;  2R7Z L;  4QIW P;  2NVT L;  3FKI L;  4BBS L;  3S2H L;  4A3K L;  3HOY L;  4A3G L;  5M3M L;  2R92 L;  4BXX L;  3S2D L;  5M5W L;  5FJ8 L;  4Y7N L;  3K7A L;  5IP9 L;  3GTM L;  3S1Q L;  4C3J L;  2PMZ P;  3CQZ L;  1TWC L;  4A3I L;  5C4X L;  1WCM L;  1TWA L;  3S15 L;  4BBR L;  2E2H L;  3M4O L;  5C3E L;  1Y1W L;  3HOV L;  2NVX L;  5IYD L;  4A3E L;  3RZD L;  5M3F L;  3S14 L;  3HOZ L;  1R9T L;  1SFO L;  4C3H L;  4A3M L;  3S1M L;  2JA6 L;  1TWH L;  3GTO L;  5IP7 L;  2NVQ L;  4X6A L;  2NVY L;  2E2I L;  5C4J L;  3HOX L;  2B63 L;  4BY7 L;  3M3Y L;  2R93 L;  4C2M 1;  1TWF L;  3HOW L;  2VUM L;  3I4N L;  2JA7 L;  4A3F L;  5M5X L;  2Y0S P;  1Y1V L;  3S1R L;  2JA8 L;  5C44 L;  4AYB P;  3GTQ L;  4A3J L;  3GTP L;  5M5Y L;  4A3L L;  3HOU L;  4Y52 L;  2E2J L;  3RZO L;  1K83 L;  4C3I L;  1TWG L;  1I3Q L;  1I50 L;  4A3C L;  3HKZ P;  2JA5 L;  4A3D L;  3S1N L;  3H3V M;  3S17 L;  4BY1 L;  2WAQ P;  3GTL L;  3I4M L;  5IYC L;  4A3B L;  1I6H L;  3GTG L;  4A93 L;  3H0G L;  5FLM L;  3S16 L;  3PO3 L;  3PO2 L;  2YU9 L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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