5FLML

Structure of transcribing mammalian rna polymerase ii
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
44
structure length
44
Chain Sequence
MIYICGECHTENEIKSRDPIRCRECGYRIMYKKRTKRLVVFDAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of Transcribing Mammalian RNA Polymerase II
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE
total genus 1
structure length 44
sequence length 44
ec nomenclature
pdb deposition date 2015-10-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 5flmL00
3GTLL 3S2DL 1Y1WL 5C4JL 1WCML 2R93L 1Y1VL 3PO2L 3CQZL 3K7AL 5IYDL 5M5YL 3S17L 2JA7L 4AYBP 4A3ML 3HOWL 1SFOL 2NVQL 5IP9L 3GTQL 4A3LL 1I50L 3S1RL 3S1ML 1TWFL 3PO3L 3RZOL 5M5WL 3GTKL 4BBSL 4Y7NL 3S1NL 1TWCL 2JA5L 3I4ML 2WB1P 4A93L 2R7ZL 5IYCL 2NVXL 1TWAL 3M4OL 4A3EL 3GTML 1K83L 2R92L 3HOYL 5IYBL 2B63L 3HOVL 2NVTL 4X6AL 3GTPL 5M3FL 4Y52L 4A3GL 3H0GL 4C2M1 3S1QL 4C3JL 2VUML 2E2IL 1TWGL 3S16L 1R9TL 5FJ8L 3S2HL 2WAQP 4BXXL 3I4NL 3GTJL 2JA8L 4C3IL 4BY7L 4A3DL 5FLML 4A3FL 2Y0SP 4A3JL 3S15L 5C4XL 4A3CL 5M3ML 5C3EL 4C3HL 2PMZP 3HOXL 2E2JL 1TWHL 2E2HL 2YU9L 4A3IL 3S14L 1I6HL 5IP7L 4BBRL 3HKZP 3RZDL 2JA6L 4A3BL 3GTGL 5M5XL 2NVYL 5C44L 3FKIL 3HOZL 3H3VM 3M3YL 1I3QL 3GTOL 3HOUL 4A3KL 4QIWP 4BY1L
chains in the Genus database with same CATH superfamily
5GAGc 3RZ6A 4B8CD 5GAEc 1DX8A 3S2DL 3CQZL 2PSMC 5M5YL 3LWQB 1NXGA 3HOWL 1RYQA 4AI1A 2NVQL 5IP9L 4A3LL 3S1ML 2XJUA 3LWVB 2XJVA 1R0FA 3RZTA 5JVH1 1LTLA 3GTKL 4BBSL 3P8BA 3S1NL 1IROA 1TWCL 3PZAA 2JA5L 4G6BA 4ME3A 2KN9A 4A93L 1RYTA 5IYCL 3KYYA 3KYUA 4A3EL 3GTML 1BQ9A 1K83L 8RXNA 1FHHA 4YWMA 4TPUA 1BE7A 3NFPI 3HOVL 4X6AL 2PVXA 3GTPL 5M3FL 4AR5A 2H12A 2HR5A 3SS2A 5MF6A 3S16L 1QYBA 1PFUA 1SMMA 4BXXL 4AR3A 1R0GA 2RDVA 3MQKB 1ZRPA 4BY7L 4A3FL 4AHXA 3P2AA 2AQCA 4C3HL 2PMZP 2HVYC 2A68D 1H7VA 3IU3I 2YU9L 4A3IL 4E6YA 1OWBA 3HKZP 3GTGL 1IU5A 5K2ME 3FKIL 1I3QL 2M4YA 4AR4A 5JVG1 2A6HD 3H97A 5DM61 5C4JL 3PWFA 1T9OA 1RB9A 3PO2L 3LWPB 2XJRA 3K7AL 5IYDL 1IU6A 2Z3QB 4AHZA 2JA7L 5MFZA 3B0AB 4XGHA 2Z3RB 1R0JA 2XJSA 3MSUA 4JAFA 4AHWA 3RZOL 4Y7NL 1SMUA 5AI2A 1VCXA 2R7ZL 1P7PA 1IW7D 5MFPA 5MGNA 2V0EA 1R0IA 1LKPA 1RDGA 3LPEB 2M4VA 3H0GL 1YUXA 2LCQA 4C2M1 3HJWB 4C3JL 2E2IL 1R9TL 2C6AA 3PKIA 2A6ED 1BQ8A 3GTJL 2GMGA 5FLML 2Y0SP 7RXNA 4A3CL 3WWNB 5RXNA 3LNLA 1YK4A 2L0ZA 5EINC 1NNQA 1LKMA 3PKJA 5MLC3 1I6HL 1BRFA 3KYWA 3RZDL 2NVYL 2QL0A 5IY0A 2ERJA 3H3VM 5AI3A 1VZHA 3GTOL 4A3KL 4QIWP 5GADc 4YWLA 1PFWA 1PZXA 3B08B 4XXBB 1E8JA 2M6OA 3GTLL 1IRNA 2JI2A 1Y1WL 1WCML 1Y1VL 5EIOC 3S17L 2CR8A 1B2JA 4A3ML 1SFOL 4U671 1FHMA 1DVBA 3A44A 1B2OA 4K9FA 3GTQL 1I50L 1BFYA 4TVMA 1VZIA 3PO3L 4V196 2XJPA 2O5JD 2RFKB 3I4ML 4AI3A 3J7Z1 4RXNA 1RWDA 3PIP1 5DM71 2NVXL 1PFVA 1TWAL 4POFA 1B71A 3PIO1 1CAAA 4WFN1 3HOYL 1QCVA 3KYXA 2EY4E 4A3GL 1NXEA 2B5ID 2KKDA 2XJTA 3KYVA 1T9QA 4LHLA 1ODHA 3S1QL 2VL6A 2NYDA 5FJ8L 3S2HL 2BE5D 2WAQP 1R0HA 5AN9H 2A69D 2ERSA 4JADA 3VPBE 5GAHc 4A3DL 3HAXC 3H99A 2CKAA 4JAGA 5M3ML 3HOXL 2E2JL 2ZIXA 1LKOA 2MS3A 2AUSB 2PYAA 4AI2A 1S2ZA 1OWCA 3QVDA 3WWLA 3MPSA 4BBRL 1RDVA 2CKCA 6RXNA 2DSXA 1WJVA 3HOUL 2XJQA 3QQCE 4AHYA 2R93L 1PFYA 2AYJA 1CADA 4AYBP 3RYGA 3JR7A 3S1RL 1TWFL 2JI3A 5M5WL 1YUZA 2WB1P 4GS7D 3M4OL 2PPTA 1SMWA 2R92L 3H9BA 5IYBL 2B63L 3FDJA 2NVTL 3ZG6A 2J9UB 4Y52L 1S30A 3LWRB 1QQTA 4AR6A 1F4LA 2APOB 2VUML 1YV1A 1JYBA 1TWGL 1VZGA 4ZN1B 2PVEA 2K2DA 2C6BA 3I4NL 3H9CA 3K35A 2JA8L 4C3IL 1YK5A 4A3JL 3S15L 5C4XL 3J7Y1 4AI0A 4JAEA 5C3EL 1C09A 2JI1A 3HJYB 1B13A 1TWHL 2E2HL 1S24A 2M6PA 3S14L 1T9PA 5IP7L 4LHNA 2JA6L 4A3BL 2V0FA 3PL5A 5M5XL 4ZN3B 3LWOB 4POGA 1Z92B 5C44L 3HOZL 5H1Sc 2V3BB 4UY81 3M3YL 4BY1L
chains in the Genus database with same CATH topology
3GTLL 3S2DL 1Y1WL 5C4JL 1WCML 2R93L 1Y1VL 3PO2L 3CQZL 3K7AL 5IYDL 5M5YL 3S17L 2JA7L 4AYBP 4A3ML 3HOWL 1SFOL 2NVQL 5IP9L 3GTQL 4A3LL 1I50L 3S1RL 3S1ML 1TWFL 3PO3L 3RZOL 5M5WL 3GTKL 4BBSL 4Y7NL 3S1NL 1TWCL 2JA5L 3I4ML 2WB1P 4A93L 2R7ZL 5IYCL 2NVXL 1TWAL 3M4OL 4A3EL 3GTML 1K83L 2R92L 3HOYL 5IYBL 2B63L 3HOVL 2NVTL 4X6AL 3GTPL 5M3FL 4Y52L 4A3GL 3H0GL 4C2M1 3S1QL 4C3JL 2VUML 2E2IL 1TWGL 3S16L 1R9TL 5FJ8L 3S2HL 2WAQP 4BXXL 3I4NL 3GTJL 2JA8L 4C3IL 4BY7L 4A3DL 5FLML 4A3FL 2Y0SP 4A3JL 3S15L 5C4XL 4A3CL 5M3ML 5C3EL 4C3HL 2PMZP 3HOXL 2E2JL 1TWHL 2E2HL 2YU9L 4A3IL 3S14L 1I6HL 5IP7L 4BBRL 3HKZP 3RZDL 2JA6L 4A3BL 3GTGL 5M5XL 2NVYL 5C44L 3FKIL 3HOZL 3H3VM 3M3YL 1I3QL 3GTOL 3HOUL 4A3KL 4QIWP 4BY1L
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GTL L;  3S2D L;  1Y1W L;  5C4J L;  1WCM L;  2R93 L;  1Y1V L;  3PO2 L;  3CQZ L;  3K7A L;  5IYD L;  5M5Y L;  3S17 L;  2JA7 L;  4AYB P;  4A3M L;  3HOW L;  1SFO L;  2NVQ L;  5IP9 L;  3GTQ L;  4A3L L;  1I50 L;  3S1R L;  3S1M L;  1TWF L;  3PO3 L;  3RZO L;  5M5W L;  3GTK L;  4BBS L;  4Y7N L;  3S1N L;  1TWC L;  2JA5 L;  3I4M L;  2WB1 P;  4A93 L;  2R7Z L;  5IYC L;  2NVX L;  1TWA L;  3M4O L;  4A3E L;  3GTM L;  1K83 L;  2R92 L;  3HOY L;  5IYB L;  2B63 L;  3HOV L;  2NVT L;  4X6A L;  3GTP L;  5M3F L;  4Y52 L;  4A3G L;  3H0G L;  4C2M 1;  3S1Q L;  4C3J L;  2VUM L;  2E2I L;  1TWG L;  3S16 L;  1R9T L;  5FJ8 L;  3S2H L;  2WAQ P;  4BXX L;  3I4N L;  3GTJ L;  2JA8 L;  4C3I L;  4BY7 L;  4A3D L;  5FLM L;  4A3F L;  2Y0S P;  4A3J L;  3S15 L;  5C4X L;  4A3C L;  5M3M L;  5C3E L;  4C3H L;  2PMZ P;  3HOX L;  2E2J L;  1TWH L;  2E2H L;  2YU9 L;  4A3I L;  3S14 L;  1I6H L;  5IP7 L;  4BBR L;  3HKZ P;  3RZD L;  2JA6 L;  4A3B L;  3GTG L;  5M5X L;  2NVY L;  5C44 L;  3FKI L;  3HOZ L;  3H3V M;  3M3Y L;  1I3Q L;  3GTO L;  3HOU L;  4A3K L;  4QIW P;  4BY1 L; 
#chains in the Genus database with same CATH topology
 5GAG c;  3RZ6 A;  4B8C D;  5GAE c;  1DX8 A;  3S2D L;  3CQZ L;  2PSM C;  5M5Y L;  3LWQ B;  1NXG A;  3HOW L;  1RYQ A;  4AI1 A;  2NVQ L;  5IP9 L;  4A3L L;  3S1M L;  2XJU A;  3LWV B;  2XJV A;  1R0F A;  3RZT A;  5JVH 1;  1LTL A;  3GTK L;  4BBS L;  3P8B A;  3S1N L;  1IRO A;  1TWC L;  3PZA A;  2JA5 L;  4G6B A;  4ME3 A;  2KN9 A;  4A93 L;  1RYT A;  5IYC L;  3KYY A;  3KYU A;  4A3E L;  3GTM L;  1BQ9 A;  1K83 L;  8RXN A;  1FHH A;  4YWM A;  4TPU A;  1BE7 A;  3NFP I;  3HOV L;  4X6A L;  2PVX A;  3GTP L;  5M3F L;  4AR5 A;  2H12 A;  2HR5 A;  3SS2 A;  5MF6 A;  3S16 L;  1QYB A;  1PFU A;  1SMM A;  4BXX L;  4AR3 A;  1R0G A;  2RDV A;  3MQK B;  1ZRP A;  4BY7 L;  4A3F L;  4AHX A;  3P2A A;  2AQC A;  4C3H L;  2PMZ P;  2HVY C;  2A68 D;  1H7V A;  3IU3 I;  2YU9 L;  4A3I L;  4E6Y A;  1OWB A;  3HKZ P;  3GTG L;  1IU5 A;  5K2M E;  3FKI L;  1I3Q L;  2M4Y A;  4AR4 A;  5JVG 1;  2A6H D;  3H97 A;  5DM6 1;  5C4J L;  3PWF A;  1T9O A;  1RB9 A;  3PO2 L;  3LWP B;  2XJR A;  3K7A L;  5IYD L;  1IU6 A;  2Z3Q B;  4AHZ A;  2JA7 L;  5MFZ A;  3B0A B;  4XGH A;  2Z3R B;  1R0J A;  2XJS A;  3MSU A;  4JAF A;  4AHW A;  3RZO L;  4Y7N L;  1SMU A;  5AI2 A;  1VCX A;  2R7Z L;  1P7P A;  1IW7 D;  5MFP A;  5MGN A;  2V0E A;  1R0I A;  1LKP A;  1RDG A;  3LPE B;  2M4V A;  3H0G L;  1YUX A;  2LCQ A;  4C2M 1;  3HJW B;  4C3J L;  2E2I L;  1R9T L;  2C6A A;  3PKI A;  2A6E D;  1BQ8 A;  3GTJ L;  2GMG A;  5FLM L;  2Y0S P;  7RXN A;  4A3C L;  3WWN B;  5RXN A;  3LNL A;  1YK4 A;  2L0Z A;  5EIN C;  1NNQ A;  1LKM A;  3PKJ A;  5MLC 3;  1I6H L;  1BRF A;  3KYW A;  3RZD L;  2NVY L;  2QL0 A;  5IY0 A;  2ERJ A;  3H3V M;  5AI3 A;  1VZH A;  3GTO L;  4A3K L;  4QIW P;  5GAD c;  4YWL A;  1PFW A;  1PZX A;  3B08 B;  4XXB B;  1E8J A;  2M6O A;  3GTL L;  1IRN A;  2JI2 A;  1Y1W L;  1WCM L;  1Y1V L;  5EIO C;  3S17 L;  2CR8 A;  1B2J A;  4A3M L;  1SFO L;  4U67 1;  1FHM A;  1DVB A;  3A44 A;  1B2O A;  4K9F A;  3GTQ L;  1I50 L;  1BFY A;  4TVM A;  1VZI A;  3PO3 L;  4V19 6;  2XJP A;  2O5J D;  2RFK B;  3I4M L;  4AI3 A;  3J7Z 1;  4RXN A;  1RWD A;  3PIP 1;  5DM7 1;  2NVX L;  1PFV A;  1TWA L;  4POF A;  1B71 A;  3PIO 1;  1CAA A;  4WFN 1;  3HOY L;  1QCV A;  3KYX A;  2EY4 E;  4A3G L;  1NXE A;  2B5I D;  2KKD A;  2XJT A;  3KYV A;  1T9Q A;  4LHL A;  1ODH A;  3S1Q L;  2VL6 A;  2NYD A;  5FJ8 L;  3S2H L;  2BE5 D;  2WAQ P;  1R0H A;  5AN9 H;  2A69 D;  2ERS A;  4JAD A;  3VPB E;  5GAH c;  4A3D L;  3HAX C;  3H99 A;  2CKA A;  4JAG A;  5M3M L;  3HOX L;  2E2J L;  2ZIX A;  1LKO A;  2MS3 A;  2AUS B;  2PYA A;  4AI2 A;  1S2Z A;  1OWC A;  3QVD A;  3WWL A;  3MPS A;  4BBR L;  1RDV A;  2CKC A;  6RXN A;  2DSX A;  1WJV A;  3HOU L;  2XJQ A;  3QQC E;  4AHY A;  2R93 L;  1PFY A;  2AYJ A;  1CAD A;  4AYB P;  3RYG A;  3JR7 A;  3S1R L;  1TWF L;  2JI3 A;  5M5W L;  1YUZ A;  2WB1 P;  4GS7 D;  3M4O L;  2PPT A;  1SMW A;  2R92 L;  3H9B A;  5IYB L;  2B63 L;  3FDJ A;  2NVT L;  3ZG6 A;  2J9U B;  4Y52 L;  1S30 A;  3LWR B;  1QQT A;  4AR6 A;  1F4L A;  2APO B;  2VUM L;  1YV1 A;  1JYB A;  1TWG L;  1VZG A;  4ZN1 B;  2PVE A;  2K2D A;  2C6B A;  3I4N L;  3H9C A;  3K35 A;  2JA8 L;  4C3I L;  1YK5 A;  4A3J L;  3S15 L;  5C4X L;  3J7Y 1;  4AI0 A;  4JAE A;  5C3E L;  1C09 A;  2JI1 A;  3HJY B;  1B13 A;  1TWH L;  2E2H L;  1S24 A;  2M6P A;  3S14 L;  1T9P A;  5IP7 L;  4LHN A;  2JA6 L;  4A3B L;  2V0F A;  3PL5 A;  5M5X L;  4ZN3 B;  3LWO B;  4POG A;  1Z92 B;  5C44 L;  3HOZ L;  5H1S c;  2V3B B;  4UY8 1;  3M3Y L;  4BY1 L; 
#chains in the Genus database with same CATH homology
 3GTL L;  3S2D L;  1Y1W L;  5C4J L;  1WCM L;  2R93 L;  1Y1V L;  3PO2 L;  3CQZ L;  3K7A L;  5IYD L;  5M5Y L;  3S17 L;  2JA7 L;  4AYB P;  4A3M L;  3HOW L;  1SFO L;  2NVQ L;  5IP9 L;  3GTQ L;  4A3L L;  1I50 L;  3S1R L;  3S1M L;  1TWF L;  3PO3 L;  3RZO L;  5M5W L;  3GTK L;  4BBS L;  4Y7N L;  3S1N L;  1TWC L;  2JA5 L;  3I4M L;  2WB1 P;  4A93 L;  2R7Z L;  5IYC L;  2NVX L;  1TWA L;  3M4O L;  4A3E L;  3GTM L;  1K83 L;  2R92 L;  3HOY L;  5IYB L;  2B63 L;  3HOV L;  2NVT L;  4X6A L;  3GTP L;  5M3F L;  4Y52 L;  4A3G L;  3H0G L;  4C2M 1;  3S1Q L;  4C3J L;  2VUM L;  2E2I L;  1TWG L;  3S16 L;  1R9T L;  5FJ8 L;  3S2H L;  2WAQ P;  4BXX L;  3I4N L;  3GTJ L;  2JA8 L;  4C3I L;  4BY7 L;  4A3D L;  5FLM L;  4A3F L;  2Y0S P;  4A3J L;  3S15 L;  5C4X L;  4A3C L;  5M3M L;  5C3E L;  4C3H L;  2PMZ P;  3HOX L;  2E2J L;  1TWH L;  2E2H L;  2YU9 L;  4A3I L;  3S14 L;  1I6H L;  5IP7 L;  4BBR L;  3HKZ P;  3RZD L;  2JA6 L;  4A3B L;  3GTG L;  5M5X L;  2NVY L;  5C44 L;  3FKI L;  3HOZ L;  3H3V M;  3M3Y L;  1I3Q L;  3GTO L;  3HOU L;  4A3K L;  4QIW P;  4BY1 L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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