5GTUA

Structural and mechanistic insights into regulation of the retromer coat by tbc1d5
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
186
structure length
186
Chain Sequence
MAGHRLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKESYDYLKTLAGDVHIVRGDFDENLNYPEQKVVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHTHKFEAFEHENKFYINPGSATGAYNALETNIIPSFVLMDIQASTVVTYVYQLIGDDVKVERIEYKKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and mechanistic insights into regulation of the retromer coat by TBC1d5
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Vacuolar protein sorting-associated protein 29
total genus 49
structure length 186
sequence length 186
ec nomenclature
pdb deposition date 2016-08-23
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 5gtuA00
1W24A 3H69A 1S3NA 2QJCA 3H64A 4M0VA 3GVEA 3DW8C 3PSNA 2XMOA 4DHLA 2IE4C 1MF8A 4KKZA 3LL8A 4ZX2A 3DSDA 3QFMA 5GTUA 2IAEC 2NYLC 2NXFA 3DSCA 2AHDA 4H1SA 3H61A 4MOYA 3ZTVA 1S3LA 1IT6A 4LACC 1S70A 3AV0A 5DNYA 2HYPA 3IVEA 3JYFA 1G5BA 4I5LC 4KBPA 4NZVA 2BCDA 3IB7A 4FCXA 4UT3B 4UWQA 2O8AA 3H63A 2BQ8X 3H60A 1OIDA 4ORBA 1S95A 2WDDA 1SU1A 1Z2XA 3THNA 5INBA 3PSOA 3RQZA 1UTEA 1QHWA 1U32A 3H66A 1XM7A 3K7WC 2O8GA 3EGGA 3QFKA 4YKEA 3RL3A 2A22A 1NNWA 1TCOA 2Z1AA 3QFOA 4I5NC 4ORCA 1KBPA 2R17A 2USHA 3ZU0A 4J6OA 4H2FA 3HVQA 3N5UA 1JK7A 3EGHA 3H67A 2NPPC 2ZBMA 5J28A 3QG5C 1S8EA 2IE3C 1HP1A 3E7BA 4O24A 2QFRA 4V0XA 4H2BA 4MOVA 4H1YP 3THOB 3CK2A 1AUIA 1HO5A 2CV9A 2HY1A 4ORAA 1II7A 4JA9A 4MP0A 1UF3A 4H2GA 3QFNA 5JPEA 2HYOA 3FGAC 1T70A 4LU9A 1WARA 4FBWA 1OIEA 2P6BA 2DFJA 2BDXA 4DSYA 3V4YA 2WDEA 4ZVZA 3T1IA 4V0VA 4V0WA 4WWLA 3TGHA 5EQVA 2Q8UA 1WAO1 2Z06A 3RL4A 2NYMC 2Z72A 5F3WA 1XZWA 2WDCA 5JJTA 3P71C 5B8IA 4DT2A 1FJMA 4FBKA 4JA7A 4TUIA 3ICFA 3H62B 2GJUA 1Z2WA 4XPNA 3H68A 3IVDA 3C9FA 1M63A 1OI8A 5C1VA 4H2IA 4LTYA 4UT2A 4UT3A 1S3MA 1QFCA 3C5WC 3AUZA 2QFPA 4G9JA 2WDFA 5JPFA 4O43A 1T71A 2JOGA 3KBPA 4FBQA 4TUGA 3E7AA 2YVTA 4IL1A 4F0ZA 1V73A 4Q7FA 4O5GA 4IYPC 4OR9A 5HPEA 3K7VC 1USHA 5IOHA 4O4KA 3IB8A 3RL5A 4HD0A 4B2OA 1HPUA 2KKNA
chains in the Genus database with same CATH superfamily
1W24A 3H69A 1S3NA 2QJCA 3H64A 4M0VA 3GVEA 3DW8C 3PSNA 2XMOA 4DHLA 2IE4C 1MF8A 4KKZA 3LL8A 4ZX2A 3DSDA 3QFMA 5GTUA 2IAEC 2NYLC 2NXFA 3DSCA 2AHDA 4H1SA 3H61A 4MOYA 3ZTVA 1S3LA 1IT6A 4LACC 1S70A 3D03A 3AV0A 5DNYA 2HYPA 3IVEA 3JYFA 1G5BA 4I5LC 4KBPA 4NZVA 2BCDA 3IB7A 2YEQA 4FCXA 4UT3B 4UWQA 2O8AA 3H63A 2BQ8X 3H60A 1OIDA 4ORBA 1S95A 2WDDA 1SU1A 1Z2XA 3THNA 5INBA 3PSOA 3RQZA 1UTEA 1QHWA 1U32A 3H66A 1XM7A 3K7WC 2O8GA 3EGGA 3QFKA 4YKEA 3RL3A 2A22A 1NNWA 1TCOA 2Z1AA 3QFOA 4I5NC 4ORCA 1KBPA 2R17A 2USHA 3ZU0A 4J6OA 4H2FA 3HVQA 3FLOA 3N5UA 1JK7A 3EGHA 3H67A 2NPPC 2ZBMA 5J28A 3QG5C 1S8EA 2IE3C 1HP1A 3E7BA 4O24A 2QFRA 2DXLA 4H2BA 4V0XA 4MOVA 4H1YP 3THOB 3CK2A 1AUIA 1HO5A 2CV9A 2HY1A 4ORAA 1II7A 4JA9A 2ZO9B 4MP0A 1UF3A 4H2GA 3QFNA 5JPEA 2HYOA 3FGAC 1T70A 4LU9A 1WARA 2DXNA 4FBWA 1OIEA 2P6BA 2DFJA 2BDXA 4DSYA 3V4YA 2WDEA 4ZVZA 3T1IA 4V0VA 2ZOAA 4V0WA 4WWLA 3TGHA 5EQVA 2Q8UA 1WAO1 2Z06A 3RL4A 2NYMC 2Z72A 5F3WA 1XZWA 2WDCA 5JJTA 3P71C 5B8IA 4DT2A 1FJMA 4FBKA 4JA7A 4TUIA 3ICFA 3H62B 2GJUA 1Z2WA 4XPNA 3H68A 3IVDA 3C9FA 1M63A 1OI8A 5C1VA 4H2IA 4LTYA 4UT2A 4UT3A 1S3MA 1QFCA 3C5WC 3AUZA 3E0JA 2QFPA 4G9JA 2WDFA 5JPFA 4O43A 1T71A 2JOGA 3KBPA 4FBQA 4TUGA 3E7AA 2YVTA 4IL1A 4F0ZA 1V73A 4Q7FA 4O5GA 4IYPC 4OR9A 5HPEA 3K7VC 1USHA 5IOHA 4O4KA 3IB8A 3RL5A 4HD0A 4B2OA 1HPUA 2KKNA
chains in the Genus database with same CATH topology
1W24A 3H69A 1S3NA 2QJCA 3H64A 4M0VA 3GVEA 3DW8C 3PSNA 2XMOA 4DHLA 2IE4C 1MF8A 4KKZA 3LL8A 4ZX2A 3DSDA 3QFMA 5GTUA 2IAEC 2NYLC 2NXFA 3DSCA 2AHDA 4H1SA 3H61A 4MOYA 3ZTVA 1S3LA 1IT6A 4LACC 1S70A 3D03A 3AV0A 5DNYA 2HYPA 3IVEA 3JYFA 1G5BA 4I5LC 4KBPA 4NZVA 2BCDA 3IB7A 2YEQA 4FCXA 4UT3B 4UWQA 2O8AA 3H63A 2BQ8X 3H60A 1OIDA 4ORBA 1S95A 2WDDA 1SU1A 1Z2XA 3THNA 5INBA 3PSOA 3RQZA 1UTEA 1QHWA 1U32A 3H66A 1XM7A 3K7WC 2O8GA 3EGGA 3QFKA 4YKEA 3RL3A 2A22A 1NNWA 1TCOA 2Z1AA 3QFOA 4I5NC 4ORCA 1KBPA 2R17A 2USHA 3ZU0A 4J6OA 4H2FA 3HVQA 3FLOA 3N5UA 1JK7A 3EGHA 3H67A 2NPPC 2ZBMA 5J28A 3QG5C 1S8EA 2IE3C 1HP1A 3E7BA 4O24A 2QFRA 2DXLA 4H2BA 4V0XA 4MOVA 4H1YP 3THOB 3CK2A 1AUIA 1HO5A 2CV9A 2HY1A 4ORAA 1II7A 4JA9A 2ZO9B 4MP0A 1UF3A 4H2GA 3QFNA 5JPEA 2HYOA 3FGAC 1T70A 4LU9A 1WARA 2DXNA 4FBWA 1OIEA 2P6BA 2DFJA 2BDXA 4DSYA 3V4YA 2WDEA 4ZVZA 3T1IA 4V0VA 2ZOAA 4V0WA 4WWLA 3TGHA 5EQVA 2Q8UA 1WAO1 2Z06A 3RL4A 2NYMC 2Z72A 5F3WA 1XZWA 2WDCA 5JJTA 3P71C 5B8IA 4DT2A 1FJMA 4FBKA 4JA7A 4TUIA 3ICFA 3H62B 2GJUA 1Z2WA 4XPNA 3H68A 3IVDA 3C9FA 1M63A 1OI8A 5C1VA 4H2IA 4LTYA 4UT2A 4UT3A 1S3MA 1QFCA 3C5WC 3AUZA 3E0JA 2QFPA 4G9JA 2WDFA 5JPFA 4O43A 1T71A 2JOGA 3KBPA 4FBQA 4TUGA 3E7AA 2YVTA 4IL1A 4F0ZA 1V73A 4Q7FA 4O5GA 4IYPC 4OR9A 5HPEA 3K7VC 1USHA 5IOHA 4O4KA 3IB8A 3RL5A 4HD0A 4B2OA 1HPUA 2KKNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1W24 A;  3H69 A;  1S3N A;  2QJC A;  3H64 A;  4M0V A;  3GVE A;  3DW8 C;  3PSN A;  2XMO A;  4DHL A;  2IE4 C;  1MF8 A;  4KKZ A;  3LL8 A;  4ZX2 A;  3DSD A;  3QFM A;  5GTU A;  2IAE C;  2NYL C;  2NXF A;  3DSC A;  2AHD A;  4H1S A;  3H61 A;  4MOY A;  3ZTV A;  1S3L A;  1IT6 A;  4LAC C;  1S70 A;  3AV0 A;  5DNY A;  2HYP A;  3IVE A;  3JYF A;  1G5B A;  4I5L C;  4KBP A;  4NZV A;  2BCD A;  3IB7 A;  4FCX A;  4UT3 B;  4UWQ A;  2O8A A;  3H63 A;  2BQ8 X;  3H60 A;  1OID A;  4ORB A;  1S95 A;  2WDD A;  1SU1 A;  1Z2X A;  3THN A;  5INB A;  3PSO A;  3RQZ A;  1UTE A;  1QHW A;  1U32 A;  3H66 A;  1XM7 A;  3K7W C;  2O8G A;  3EGG A;  3QFK A;  4YKE A;  3RL3 A;  2A22 A;  1NNW A;  1TCO A;  2Z1A A;  3QFO A;  4I5N C;  4ORC A;  1KBP A;  2R17 A;  2USH A;  3ZU0 A;  4J6O A;  4H2F A;  3HVQ A;  3N5U A;  1JK7 A;  3EGH A;  3H67 A;  2NPP C;  2ZBM A;  5J28 A;  3QG5 C;  1S8E A;  2IE3 C;  1HP1 A;  3E7B A;  4O24 A;  2QFR A;  4V0X A;  4H2B A;  4MOV A;  4H1Y P;  3THO B;  3CK2 A;  1AUI A;  1HO5 A;  2CV9 A;  2HY1 A;  4ORA A;  1II7 A;  4JA9 A;  4MP0 A;  1UF3 A;  4H2G A;  3QFN A;  5JPE A;  2HYO A;  3FGA C;  1T70 A;  4LU9 A;  1WAR A;  4FBW A;  1OIE A;  2P6B A;  2DFJ A;  2BDX A;  4DSY A;  3V4Y A;  2WDE A;  4ZVZ A;  3T1I A;  4V0V A;  4V0W A;  4WWL A;  3TGH A;  5EQV A;  2Q8U A;  1WAO 1;  2Z06 A;  3RL4 A;  2NYM C;  2Z72 A;  5F3W A;  1XZW A;  2WDC A;  5JJT A;  3P71 C;  5B8I A;  4DT2 A;  1FJM A;  4FBK A;  4JA7 A;  4TUI A;  3ICF A;  3H62 B;  2GJU A;  1Z2W A;  4XPN A;  3H68 A;  3IVD A;  3C9F A;  1M63 A;  1OI8 A;  5C1V A;  4H2I A;  4LTY A;  4UT2 A;  4UT3 A;  1S3M A;  1QFC A;  3C5W C;  3AUZ A;  2QFP A;  4G9J A;  2WDF A;  5JPF A;  4O43 A;  1T71 A;  2JOG A;  3KBP A;  4FBQ A;  4TUG A;  3E7A A;  2YVT A;  4IL1 A;  4F0Z A;  1V73 A;  4Q7F A;  4O5G A;  4IYP C;  4OR9 A;  5HPE A;  3K7V C;  1USH A;  5IOH A;  4O4K A;  3IB8 A;  3RL5 A;  4HD0 A;  4B2O A;  1HPU A;  2KKN A; 
#chains in the Genus database with same CATH topology
 1W24 A;  3H69 A;  1S3N A;  2QJC A;  3H64 A;  4M0V A;  3GVE A;  3DW8 C;  3PSN A;  2XMO A;  4DHL A;  2IE4 C;  1MF8 A;  4KKZ A;  3LL8 A;  4ZX2 A;  3DSD A;  3QFM A;  5GTU A;  2IAE C;  2NYL C;  2NXF A;  3DSC A;  2AHD A;  4H1S A;  3H61 A;  4MOY A;  3ZTV A;  1S3L A;  1IT6 A;  4LAC C;  1S70 A;  3D03 A;  3AV0 A;  5DNY A;  2HYP A;  3IVE A;  3JYF A;  1G5B A;  4I5L C;  4KBP A;  4NZV A;  2BCD A;  3IB7 A;  2YEQ A;  4FCX A;  4UT3 B;  4UWQ A;  2O8A A;  3H63 A;  2BQ8 X;  3H60 A;  1OID A;  4ORB A;  1S95 A;  2WDD A;  1SU1 A;  1Z2X A;  3THN A;  5INB A;  3PSO A;  3RQZ A;  1UTE A;  1QHW A;  1U32 A;  3H66 A;  1XM7 A;  3K7W C;  2O8G A;  3EGG A;  3QFK A;  4YKE A;  3RL3 A;  2A22 A;  1NNW A;  1TCO A;  2Z1A A;  3QFO A;  4I5N C;  4ORC A;  1KBP A;  2R17 A;  2USH A;  3ZU0 A;  4J6O A;  4H2F A;  3HVQ A;  3FLO A;  3N5U A;  1JK7 A;  3EGH A;  3H67 A;  2NPP C;  2ZBM A;  5J28 A;  3QG5 C;  1S8E A;  2IE3 C;  1HP1 A;  3E7B A;  4O24 A;  2QFR A;  2DXL A;  4H2B A;  4V0X A;  4MOV A;  4H1Y P;  3THO B;  3CK2 A;  1AUI A;  1HO5 A;  2CV9 A;  2HY1 A;  4ORA A;  1II7 A;  4JA9 A;  2ZO9 B;  4MP0 A;  1UF3 A;  4H2G A;  3QFN A;  5JPE A;  2HYO A;  3FGA C;  1T70 A;  4LU9 A;  1WAR A;  2DXN A;  4FBW A;  1OIE A;  2P6B A;  2DFJ A;  2BDX A;  4DSY A;  3V4Y A;  2WDE A;  4ZVZ A;  3T1I A;  4V0V A;  2ZOA A;  4V0W A;  4WWL A;  3TGH A;  5EQV A;  2Q8U A;  1WAO 1;  2Z06 A;  3RL4 A;  2NYM C;  2Z72 A;  5F3W A;  1XZW A;  2WDC A;  5JJT A;  3P71 C;  5B8I A;  4DT2 A;  1FJM A;  4FBK A;  4JA7 A;  4TUI A;  3ICF A;  3H62 B;  2GJU A;  1Z2W A;  4XPN A;  3H68 A;  3IVD A;  3C9F A;  1M63 A;  1OI8 A;  5C1V A;  4H2I A;  4LTY A;  4UT2 A;  4UT3 A;  1S3M A;  1QFC A;  3C5W C;  3AUZ A;  3E0J A;  2QFP A;  4G9J A;  2WDF A;  5JPF A;  4O43 A;  1T71 A;  2JOG A;  3KBP A;  4FBQ A;  4TUG A;  3E7A A;  2YVT A;  4IL1 A;  4F0Z A;  1V73 A;  4Q7F A;  4O5G A;  4IYP C;  4OR9 A;  5HPE A;  3K7V C;  1USH A;  5IOH A;  4O4K A;  3IB8 A;  3RL5 A;  4HD0 A;  4B2O A;  1HPU A;  2KKN A; 
#chains in the Genus database with same CATH homology
 1W24 A;  3H69 A;  1S3N A;  2QJC A;  3H64 A;  4M0V A;  3GVE A;  3DW8 C;  3PSN A;  2XMO A;  4DHL A;  2IE4 C;  1MF8 A;  4KKZ A;  3LL8 A;  4ZX2 A;  3DSD A;  3QFM A;  5GTU A;  2IAE C;  2NYL C;  2NXF A;  3DSC A;  2AHD A;  4H1S A;  3H61 A;  4MOY A;  3ZTV A;  1S3L A;  1IT6 A;  4LAC C;  1S70 A;  3D03 A;  3AV0 A;  5DNY A;  2HYP A;  3IVE A;  3JYF A;  1G5B A;  4I5L C;  4KBP A;  4NZV A;  2BCD A;  3IB7 A;  2YEQ A;  4FCX A;  4UT3 B;  4UWQ A;  2O8A A;  3H63 A;  2BQ8 X;  3H60 A;  1OID A;  4ORB A;  1S95 A;  2WDD A;  1SU1 A;  1Z2X A;  3THN A;  5INB A;  3PSO A;  3RQZ A;  1UTE A;  1QHW A;  1U32 A;  3H66 A;  1XM7 A;  3K7W C;  2O8G A;  3EGG A;  3QFK A;  4YKE A;  3RL3 A;  2A22 A;  1NNW A;  1TCO A;  2Z1A A;  3QFO A;  4I5N C;  4ORC A;  1KBP A;  2R17 A;  2USH A;  3ZU0 A;  4J6O A;  4H2F A;  3HVQ A;  3FLO A;  3N5U A;  1JK7 A;  3EGH A;  3H67 A;  2NPP C;  2ZBM A;  5J28 A;  3QG5 C;  1S8E A;  2IE3 C;  1HP1 A;  3E7B A;  4O24 A;  2QFR A;  2DXL A;  4H2B A;  4V0X A;  4MOV A;  4H1Y P;  3THO B;  3CK2 A;  1AUI A;  1HO5 A;  2CV9 A;  2HY1 A;  4ORA A;  1II7 A;  4JA9 A;  2ZO9 B;  4MP0 A;  1UF3 A;  4H2G A;  3QFN A;  5JPE A;  2HYO A;  3FGA C;  1T70 A;  4LU9 A;  1WAR A;  2DXN A;  4FBW A;  1OIE A;  2P6B A;  2DFJ A;  2BDX A;  4DSY A;  3V4Y A;  2WDE A;  4ZVZ A;  3T1I A;  4V0V A;  2ZOA A;  4V0W A;  4WWL A;  3TGH A;  5EQV A;  2Q8U A;  1WAO 1;  2Z06 A;  3RL4 A;  2NYM C;  2Z72 A;  5F3W A;  1XZW A;  2WDC A;  5JJT A;  3P71 C;  5B8I A;  4DT2 A;  1FJM A;  4FBK A;  4JA7 A;  4TUI A;  3ICF A;  3H62 B;  2GJU A;  1Z2W A;  4XPN A;  3H68 A;  3IVD A;  3C9F A;  1M63 A;  1OI8 A;  5C1V A;  4H2I A;  4LTY A;  4UT2 A;  4UT3 A;  1S3M A;  1QFC A;  3C5W C;  3AUZ A;  3E0J A;  2QFP A;  4G9J A;  2WDF A;  5JPF A;  4O43 A;  1T71 A;  2JOG A;  3KBP A;  4FBQ A;  4TUG A;  3E7A A;  2YVT A;  4IL1 A;  4F0Z A;  1V73 A;  4Q7F A;  4O5G A;  4IYP C;  4OR9 A;  5HPE A;  3K7V C;  1USH A;  5IOH A;  4O4K A;  3IB8 A;  3RL5 A;  4HD0 A;  4B2O A;  1HPU A;  2KKN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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