5IOHA

Repoman-pp1a (protein phosphatase 1, alpha isoform) holoenzyme complex
Total Genus 104
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
104
sequence length
293
structure length
293
Chain Sequence
LNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/protein binding
source organism Homo sapiens
publication title The Ki-67 and RepoMan mitotic phosphatases assemble via an identical, yet novel mechanism.
pubmed doi rcsb
molecule keywords Serine/threonine-protein phosphatase PP1-alpha catalytic sub
total genus 104
structure length 293
sequence length 293
chains with identical sequence C
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2016-03-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
A PF16891 STPPase_N Serine-threonine protein phosphatase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 5iohA00
2YVTA 4HD0A 3C9FA 4I5NC 3QG5C 5DNYA 2WDDA 3PSNA 2GJUA 3THNA 5F3WA 3AV0A 1AUIA 2JOGA 4FBKA 1SU1A 4DHLA 4ORCA 4FCXA 1Z2WA 1W24A 4KKZA 1S8EA 3C5WC 2HYOA 1OI8A 3IB7A 3H64A 2AHDA 1S95A 1TCOA 2WDFA 3QFOA 5JJTA 3IVDA 3AUZA 1KBPA 3RL4A 1HP1A 3HVQA 2QFRA 4UT3A 2CV9A 1S3MA 2O8AA 1M63A 3RQZA 4TUIA 4MP0A 4JA9A 1HO5A 5IOHA 3ZU0A 3KBPA 2QJCA 1S70A 1NNWA 3GVEA 3PSOA 4DSYA 4KBPA 1QHWA 4LU9A 3H66A 1OIDA 3QFMA 4MOYA 5JPFA 3K7WC 4H2GA 4H1SA 4TUGA 3H63A 2HYPA 5B8IA 3JYFA 4F0ZA 2WDEA 4WWLA 2HY1A 2DFJA 1FJMA 4JA7A 5EQVA 3RL5A 1G5BA 1T71A 1Z2XA 3QFNA 4UT3B 3K7VC 1WAO1 4G9JA 4ZVZA 2USHA 1IT6A 2XMOA 5HPEA 4UT2A 3V4YA 4B2OA 4M0VA 4XPNA 1QFCA 3DSCA 3LL8A 1WARA 1UF3A 1II7A 4Q7FA 3E7AA 4O24A 1HPUA 2R17A 2KKNA 3H68A 4O4KA 1UTEA 2BDXA 1S3NA 4H2FA 4IL1A 2P6BA 3P71C 3H60A 4V0WA 5JPEA 3IB8A 4ORAA 4UWQA 2Z72A 3ICFA 1OIEA 4OR9A 1S3LA 1T70A 4MOVA 2NYLC 3RL3A 4H2BA 2NYMC 1JK7A 4LACC 4LTYA 4V0VA 5GTUA 1USHA 3T1IA 2NPPC 2Q8UA 1V73A 3H69A 3N5UA 2ZBMA 4V0XA 5INBA 1XZWA 3H62B 3H67A 4H2IA 3QFKA 4NZVA 3ZTVA 3E7BA 4ORBA 2IE3C 4FBWA 2A22A 3H61A 3DW8C 4FBQA 4I5LC 5C1VA 2WDCA 3EGHA 4H1YP 4O43A 3CK2A 1MF8A 2IE4C 2QFPA 4O5GA 4DT2A 3TGHA 1U32A 2BQ8X 2Z06A 2Z1AA 3EGGA 3FGAC 4J6OA 3THOB 4ZX2A 2IAEC 3DSDA 4YKEA 4IYPC 2NXFA 2BCDA 1XM7A 3IVEA 2O8GA 5J28A
chains in the Genus database with same CATH superfamily
2YVTA 4HD0A 3C9FA 4I5NC 3QG5C 5DNYA 2WDDA 3PSNA 2GJUA 3THNA 5F3WA 3AV0A 1AUIA 2JOGA 4FBKA 1SU1A 4DHLA 4ORCA 4FCXA 1Z2WA 1W24A 4KKZA 1S8EA 3C5WC 2HYOA 1OI8A 3IB7A 3H64A 2AHDA 1S95A 2ZOAA 1TCOA 2WDFA 3QFOA 5JJTA 3IVDA 3AUZA 1KBPA 3RL4A 1HP1A 3HVQA 2QFRA 4UT3A 2CV9A 1S3MA 2O8AA 1M63A 3RQZA 4TUIA 4MP0A 4JA9A 1HO5A 5IOHA 3ZU0A 3KBPA 2QJCA 1S70A 1NNWA 3GVEA 3PSOA 4DSYA 4KBPA 1QHWA 3FLOA 4LU9A 3H66A 1OIDA 3QFMA 4MOYA 5JPFA 3K7WC 4H2GA 4H1SA 4TUGA 3H63A 2DXNA 2HYPA 5B8IA 3JYFA 2DXLA 4F0ZA 2WDEA 2ZO9B 4WWLA 2HY1A 2DFJA 1FJMA 4JA7A 5EQVA 3RL5A 1G5BA 1T71A 1Z2XA 3QFNA 4UT3B 3K7VC 3D03A 1WAO1 4G9JA 4ZVZA 2USHA 1IT6A 2XMOA 5HPEA 4UT2A 3V4YA 4B2OA 4M0VA 4XPNA 1QFCA 3DSCA 3LL8A 1WARA 1UF3A 1II7A 4Q7FA 3E7AA 4O24A 1HPUA 2R17A 2KKNA 3H68A 4O4KA 1UTEA 2BDXA 1S3NA 4H2FA 4IL1A 2P6BA 2YEQA 3P71C 3H60A 4V0WA 5JPEA 3IB8A 4ORAA 4UWQA 2Z72A 3E0JA 3ICFA 1OIEA 4OR9A 1S3LA 1T70A 4MOVA 2NYLC 3RL3A 4H2BA 2NYMC 1JK7A 4LACC 4LTYA 4V0VA 5GTUA 1USHA 3T1IA 2NPPC 2Q8UA 1V73A 3H69A 3N5UA 2ZBMA 4V0XA 5INBA 1XZWA 3H62B 3H67A 4H2IA 3QFKA 4NZVA 3ZTVA 3E7BA 4ORBA 2IE3C 4FBWA 2A22A 3H61A 3DW8C 4FBQA 4I5LC 5C1VA 2WDCA 3EGHA 4H1YP 4O43A 3CK2A 1MF8A 2IE4C 2QFPA 4O5GA 4DT2A 3TGHA 1U32A 2BQ8X 2Z06A 2Z1AA 3EGGA 3FGAC 4J6OA 3THOB 4ZX2A 2IAEC 3DSDA 4YKEA 4IYPC 2NXFA 2BCDA 1XM7A 3IVEA 2O8GA 5J28A
chains in the Genus database with same CATH topology
2YVTA 4HD0A 3C9FA 4I5NC 3QG5C 5DNYA 2WDDA 3PSNA 2GJUA 3THNA 5F3WA 3AV0A 1AUIA 2JOGA 4FBKA 1SU1A 4DHLA 4ORCA 4FCXA 1Z2WA 1W24A 4KKZA 1S8EA 3C5WC 2HYOA 1OI8A 3IB7A 3H64A 2AHDA 1S95A 2ZOAA 1TCOA 2WDFA 3QFOA 5JJTA 3IVDA 3AUZA 1KBPA 3RL4A 1HP1A 3HVQA 2QFRA 4UT3A 2CV9A 1S3MA 2O8AA 1M63A 3RQZA 4TUIA 4MP0A 4JA9A 1HO5A 5IOHA 3ZU0A 3KBPA 2QJCA 1S70A 1NNWA 3GVEA 3PSOA 4DSYA 4KBPA 1QHWA 3FLOA 4LU9A 3H66A 1OIDA 3QFMA 4MOYA 5JPFA 3K7WC 4H2GA 4H1SA 4TUGA 3H63A 2DXNA 2HYPA 5B8IA 3JYFA 2DXLA 4F0ZA 2WDEA 2ZO9B 4WWLA 2HY1A 2DFJA 1FJMA 4JA7A 5EQVA 3RL5A 1G5BA 1T71A 1Z2XA 3QFNA 4UT3B 3K7VC 3D03A 1WAO1 4G9JA 4ZVZA 2USHA 1IT6A 2XMOA 5HPEA 4UT2A 3V4YA 4B2OA 4M0VA 4XPNA 1QFCA 3DSCA 3LL8A 1WARA 1UF3A 1II7A 4Q7FA 3E7AA 4O24A 1HPUA 2R17A 2KKNA 3H68A 4O4KA 1UTEA 2BDXA 1S3NA 4H2FA 4IL1A 2P6BA 2YEQA 3P71C 3H60A 4V0WA 5JPEA 3IB8A 4ORAA 4UWQA 2Z72A 3E0JA 3ICFA 1OIEA 4OR9A 1S3LA 1T70A 4MOVA 2NYLC 3RL3A 4H2BA 2NYMC 1JK7A 4LACC 4LTYA 4V0VA 5GTUA 1USHA 3T1IA 2NPPC 2Q8UA 1V73A 3H69A 3N5UA 2ZBMA 4V0XA 5INBA 1XZWA 3H62B 3H67A 4H2IA 3QFKA 4NZVA 3ZTVA 3E7BA 4ORBA 2IE3C 4FBWA 2A22A 3H61A 3DW8C 4FBQA 4I5LC 5C1VA 2WDCA 3EGHA 4H1YP 4O43A 3CK2A 1MF8A 2IE4C 2QFPA 4O5GA 4DT2A 3TGHA 1U32A 2BQ8X 2Z06A 2Z1AA 3EGGA 3FGAC 4J6OA 3THOB 4ZX2A 2IAEC 3DSDA 4YKEA 4IYPC 2NXFA 2BCDA 1XM7A 3IVEA 2O8GA 5J28A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YVT A;  4HD0 A;  3C9F A;  4I5N C;  3QG5 C;  5DNY A;  2WDD A;  3PSN A;  2GJU A;  3THN A;  5F3W A;  3AV0 A;  1AUI A;  2JOG A;  4FBK A;  1SU1 A;  4DHL A;  4ORC A;  4FCX A;  1Z2W A;  1W24 A;  4KKZ A;  1S8E A;  3C5W C;  2HYO A;  1OI8 A;  3IB7 A;  3H64 A;  2AHD A;  1S95 A;  1TCO A;  2WDF A;  3QFO A;  5JJT A;  3IVD A;  3AUZ A;  1KBP A;  3RL4 A;  1HP1 A;  3HVQ A;  2QFR A;  4UT3 A;  2CV9 A;  1S3M A;  2O8A A;  1M63 A;  3RQZ A;  4TUI A;  4MP0 A;  4JA9 A;  1HO5 A;  5IOH A;  3ZU0 A;  3KBP A;  2QJC A;  1S70 A;  1NNW A;  3GVE A;  3PSO A;  4DSY A;  4KBP A;  1QHW A;  4LU9 A;  3H66 A;  1OID A;  3QFM A;  4MOY A;  5JPF A;  3K7W C;  4H2G A;  4H1S A;  4TUG A;  3H63 A;  2HYP A;  5B8I A;  3JYF A;  4F0Z A;  2WDE A;  4WWL A;  2HY1 A;  2DFJ A;  1FJM A;  4JA7 A;  5EQV A;  3RL5 A;  1G5B A;  1T71 A;  1Z2X A;  3QFN A;  4UT3 B;  3K7V C;  1WAO 1;  4G9J A;  4ZVZ A;  2USH A;  1IT6 A;  2XMO A;  5HPE A;  4UT2 A;  3V4Y A;  4B2O A;  4M0V A;  4XPN A;  1QFC A;  3DSC A;  3LL8 A;  1WAR A;  1UF3 A;  1II7 A;  4Q7F A;  3E7A A;  4O24 A;  1HPU A;  2R17 A;  2KKN A;  3H68 A;  4O4K A;  1UTE A;  2BDX A;  1S3N A;  4H2F A;  4IL1 A;  2P6B A;  3P71 C;  3H60 A;  4V0W A;  5JPE A;  3IB8 A;  4ORA A;  4UWQ A;  2Z72 A;  3ICF A;  1OIE A;  4OR9 A;  1S3L A;  1T70 A;  4MOV A;  2NYL C;  3RL3 A;  4H2B A;  2NYM C;  1JK7 A;  4LAC C;  4LTY A;  4V0V A;  5GTU A;  1USH A;  3T1I A;  2NPP C;  2Q8U A;  1V73 A;  3H69 A;  3N5U A;  2ZBM A;  4V0X A;  5INB A;  1XZW A;  3H62 B;  3H67 A;  4H2I A;  3QFK A;  4NZV A;  3ZTV A;  3E7B A;  4ORB A;  2IE3 C;  4FBW A;  2A22 A;  3H61 A;  3DW8 C;  4FBQ A;  4I5L C;  5C1V A;  2WDC A;  3EGH A;  4H1Y P;  4O43 A;  3CK2 A;  1MF8 A;  2IE4 C;  2QFP A;  4O5G A;  4DT2 A;  3TGH A;  1U32 A;  2BQ8 X;  2Z06 A;  2Z1A A;  3EGG A;  3FGA C;  4J6O A;  3THO B;  4ZX2 A;  2IAE C;  3DSD A;  4YKE A;  4IYP C;  2NXF A;  2BCD A;  1XM7 A;  3IVE A;  2O8G A;  5J28 A; 
#chains in the Genus database with same CATH topology
 2YVT A;  4HD0 A;  3C9F A;  4I5N C;  3QG5 C;  5DNY A;  2WDD A;  3PSN A;  2GJU A;  3THN A;  5F3W A;  3AV0 A;  1AUI A;  2JOG A;  4FBK A;  1SU1 A;  4DHL A;  4ORC A;  4FCX A;  1Z2W A;  1W24 A;  4KKZ A;  1S8E A;  3C5W C;  2HYO A;  1OI8 A;  3IB7 A;  3H64 A;  2AHD A;  1S95 A;  2ZOA A;  1TCO A;  2WDF A;  3QFO A;  5JJT A;  3IVD A;  3AUZ A;  1KBP A;  3RL4 A;  1HP1 A;  3HVQ A;  2QFR A;  4UT3 A;  2CV9 A;  1S3M A;  2O8A A;  1M63 A;  3RQZ A;  4TUI A;  4MP0 A;  4JA9 A;  1HO5 A;  5IOH A;  3ZU0 A;  3KBP A;  2QJC A;  1S70 A;  1NNW A;  3GVE A;  3PSO A;  4DSY A;  4KBP A;  1QHW A;  3FLO A;  4LU9 A;  3H66 A;  1OID A;  3QFM A;  4MOY A;  5JPF A;  3K7W C;  4H2G A;  4H1S A;  4TUG A;  3H63 A;  2DXN A;  2HYP A;  5B8I A;  3JYF A;  2DXL A;  4F0Z A;  2WDE A;  2ZO9 B;  4WWL A;  2HY1 A;  2DFJ A;  1FJM A;  4JA7 A;  5EQV A;  3RL5 A;  1G5B A;  1T71 A;  1Z2X A;  3QFN A;  4UT3 B;  3K7V C;  3D03 A;  1WAO 1;  4G9J A;  4ZVZ A;  2USH A;  1IT6 A;  2XMO A;  5HPE A;  4UT2 A;  3V4Y A;  4B2O A;  4M0V A;  4XPN A;  1QFC A;  3DSC A;  3LL8 A;  1WAR A;  1UF3 A;  1II7 A;  4Q7F A;  3E7A A;  4O24 A;  1HPU A;  2R17 A;  2KKN A;  3H68 A;  4O4K A;  1UTE A;  2BDX A;  1S3N A;  4H2F A;  4IL1 A;  2P6B A;  2YEQ A;  3P71 C;  3H60 A;  4V0W A;  5JPE A;  3IB8 A;  4ORA A;  4UWQ A;  2Z72 A;  3E0J A;  3ICF A;  1OIE A;  4OR9 A;  1S3L A;  1T70 A;  4MOV A;  2NYL C;  3RL3 A;  4H2B A;  2NYM C;  1JK7 A;  4LAC C;  4LTY A;  4V0V A;  5GTU A;  1USH A;  3T1I A;  2NPP C;  2Q8U A;  1V73 A;  3H69 A;  3N5U A;  2ZBM A;  4V0X A;  5INB A;  1XZW A;  3H62 B;  3H67 A;  4H2I A;  3QFK A;  4NZV A;  3ZTV A;  3E7B A;  4ORB A;  2IE3 C;  4FBW A;  2A22 A;  3H61 A;  3DW8 C;  4FBQ A;  4I5L C;  5C1V A;  2WDC A;  3EGH A;  4H1Y P;  4O43 A;  3CK2 A;  1MF8 A;  2IE4 C;  2QFP A;  4O5G A;  4DT2 A;  3TGH A;  1U32 A;  2BQ8 X;  2Z06 A;  2Z1A A;  3EGG A;  3FGA C;  4J6O A;  3THO B;  4ZX2 A;  2IAE C;  3DSD A;  4YKE A;  4IYP C;  2NXF A;  2BCD A;  1XM7 A;  3IVE A;  2O8G A;  5J28 A; 
#chains in the Genus database with same CATH homology
 2YVT A;  4HD0 A;  3C9F A;  4I5N C;  3QG5 C;  5DNY A;  2WDD A;  3PSN A;  2GJU A;  3THN A;  5F3W A;  3AV0 A;  1AUI A;  2JOG A;  4FBK A;  1SU1 A;  4DHL A;  4ORC A;  4FCX A;  1Z2W A;  1W24 A;  4KKZ A;  1S8E A;  3C5W C;  2HYO A;  1OI8 A;  3IB7 A;  3H64 A;  2AHD A;  1S95 A;  2ZOA A;  1TCO A;  2WDF A;  3QFO A;  5JJT A;  3IVD A;  3AUZ A;  1KBP A;  3RL4 A;  1HP1 A;  3HVQ A;  2QFR A;  4UT3 A;  2CV9 A;  1S3M A;  2O8A A;  1M63 A;  3RQZ A;  4TUI A;  4MP0 A;  4JA9 A;  1HO5 A;  5IOH A;  3ZU0 A;  3KBP A;  2QJC A;  1S70 A;  1NNW A;  3GVE A;  3PSO A;  4DSY A;  4KBP A;  1QHW A;  3FLO A;  4LU9 A;  3H66 A;  1OID A;  3QFM A;  4MOY A;  5JPF A;  3K7W C;  4H2G A;  4H1S A;  4TUG A;  3H63 A;  2DXN A;  2HYP A;  5B8I A;  3JYF A;  2DXL A;  4F0Z A;  2WDE A;  2ZO9 B;  4WWL A;  2HY1 A;  2DFJ A;  1FJM A;  4JA7 A;  5EQV A;  3RL5 A;  1G5B A;  1T71 A;  1Z2X A;  3QFN A;  4UT3 B;  3K7V C;  3D03 A;  1WAO 1;  4G9J A;  4ZVZ A;  2USH A;  1IT6 A;  2XMO A;  5HPE A;  4UT2 A;  3V4Y A;  4B2O A;  4M0V A;  4XPN A;  1QFC A;  3DSC A;  3LL8 A;  1WAR A;  1UF3 A;  1II7 A;  4Q7F A;  3E7A A;  4O24 A;  1HPU A;  2R17 A;  2KKN A;  3H68 A;  4O4K A;  1UTE A;  2BDX A;  1S3N A;  4H2F A;  4IL1 A;  2P6B A;  2YEQ A;  3P71 C;  3H60 A;  4V0W A;  5JPE A;  3IB8 A;  4ORA A;  4UWQ A;  2Z72 A;  3E0J A;  3ICF A;  1OIE A;  4OR9 A;  1S3L A;  1T70 A;  4MOV A;  2NYL C;  3RL3 A;  4H2B A;  2NYM C;  1JK7 A;  4LAC C;  4LTY A;  4V0V A;  5GTU A;  1USH A;  3T1I A;  2NPP C;  2Q8U A;  1V73 A;  3H69 A;  3N5U A;  2ZBM A;  4V0X A;  5INB A;  1XZW A;  3H62 B;  3H67 A;  4H2I A;  3QFK A;  4NZV A;  3ZTV A;  3E7B A;  4ORB A;  2IE3 C;  4FBW A;  2A22 A;  3H61 A;  3DW8 C;  4FBQ A;  4I5L C;  5C1V A;  2WDC A;  3EGH A;  4H1Y P;  4O43 A;  3CK2 A;  1MF8 A;  2IE4 C;  2QFP A;  4O5G A;  4DT2 A;  3TGH A;  1U32 A;  2BQ8 X;  2Z06 A;  2Z1A A;  3EGG A;  3FGA C;  4J6O A;  3THO B;  4ZX2 A;  2IAE C;  3DSD A;  4YKE A;  4IYP C;  2NXF A;  2BCD A;  1XM7 A;  3IVE A;  2O8G A;  5J28 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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