5J28A

Ki67-pp1g (protein phosphatase 1, gamma isoform) holoenzyme complex
Total Genus 106
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
106
sequence length
293
structure length
293
Chain Sequence
LNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Ki-67 and RepoMan mitotic phosphatases assemble via an identical, yet novel mechanism.
pubmed doi rcsb
molecule tags Hydrolase/protein binding
source organism Homo sapiens
molecule keywords Serine/threonine-protein phosphatase PP1-gamma catalytic sub
total genus 106
structure length 293
sequence length 293
chains with identical sequence B
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2016-03-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
A PF16891 STPPase_N Serine-threonine protein phosphatase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 5j28A00
4I5LC 2USHA 5IOHA 2R17A 5F3WA 4I5NC 4UT2A 3PSOA 3K7VC 5JPEA 3LL8A 1OIEA 1G5BA 2BDXA 2GJUA 4H2GA 2HYPA 4KBPA 5GTUA 4UT3A 1T71A 2Z1AA 4YKEA 2WDCA 1S95A 2DFJA 4MOVA 2YVTA 1USHA 3RL4A 3RL5A 1M63A 3PSNA 3DSDA 1U32A 3ZU0A 3EGHA 5DNYA 4H2BA 2QFPA 4F0ZA 1S3LA 2QFRA 1OIDA 1HPUA 3IVEA 4IL1A 4ORCA 1S70A 2XMOA 3T1IA 3H68A 2HYOA 4O43A 4H2FA 3H64A 4Q7FA 2NPPC 1MF8A 3JYFA 1UF3A 4TUIA 3C5WC 2WDDA 1AUIA 1NNWA 4OR9A 1UTEA 3H69A 4MP0A 4MOYA 4V0WA 4UWQA 3IB8A 1XZWA 2NYLC 1W24A 3KBPA 5INBA 1QHWA 5HPEA 4ORBA 1S8EA 1WAO1 3N5UA 3QFOA 3IVDA 3IB7A 4TUGA 3QFKA 1HO5A 3HVQA 4ORAA 1V73A 4B2OA 5B8IA 4DSYA 2NXFA 2KKNA 2O8AA 2Z72A 2Q8UA 4FBQA 1Z2XA 1FJMA 3AUZA 3DW8C 3E7BA 3CK2A 3K7WC 1OI8A 4LTYA 5JPFA 2BCDA 1TCOA 5C1VA 1II7A 2IAEC 2IE3C 4LACC 1QFCA 4O24A 5J28A 5EQVA 3QG5C 2IE4C 1IT6A 4LU9A 4V0XA 2NYMC 2P6BA 2WDFA 3GVEA 1WARA 3THOB 4NZVA 3RL3A 3C9FA 1XM7A 3TGHA 1JK7A 4FBKA 2Z06A 4H1SA 3H60A 4ZVZA 4DT2A 3ICFA 4FBWA 4O5GA 4XPNA 3H67A 1KBPA 2JOGA 4J6OA 3H62B 2CV9A 3ZTVA 4M0VA 4KKZA 3AV0A 4G9JA 3V4YA 3H66A 4DHLA 4IYPC 2BQ8X 3FGAC 3H63A 4V0VA 3H61A 2WDEA 4HD0A 1HP1A 3DSCA 2HY1A 1S3NA 3EGGA 4ZX2A 1SU1A 3RQZA 4JA9A 2AHDA 3QFMA 3QFNA 4UT3B 3THNA 1T70A 5JJTA 3P71C 3E7AA 2QJCA 4O4KA 4WWLA 1Z2WA 2A22A 4FCXA 1S3MA 4JA7A 4H2IA 2ZBMA 4H1YP 2O8GA
chains in the Genus database with same CATH superfamily
4I5LC 2USHA 5IOHA 2R17A 5F3WA 4I5NC 4UT2A 3PSOA 3K7VC 5JPEA 3LL8A 1OIEA 1G5BA 2BDXA 2GJUA 4H2GA 2HYPA 4KBPA 5GTUA 4UT3A 1T71A 2Z1AA 4YKEA 2WDCA 1S95A 2DFJA 4MOVA 2YVTA 1USHA 3RL4A 3RL5A 1M63A 3PSNA 3DSDA 1U32A 3ZU0A 3EGHA 5DNYA 4H2BA 2QFPA 4F0ZA 1S3LA 2QFRA 1OIDA 1HPUA 3IVEA 4IL1A 4ORCA 1S70A 2ZOAA 2XMOA 3T1IA 3H68A 2HYOA 3E0JA 4O43A 4H2FA 3H64A 4Q7FA 2NPPC 1MF8A 3JYFA 1UF3A 4TUIA 3C5WC 2WDDA 1AUIA 1NNWA 4OR9A 1UTEA 3H69A 4MP0A 4MOYA 4V0WA 4UWQA 3IB8A 2NYLC 1XZWA 1W24A 3KBPA 5INBA 1QHWA 3D03A 5HPEA 4ORBA 1S8EA 1WAO1 3N5UA 3QFOA 3IVDA 3IB7A 4TUGA 3QFKA 1HO5A 3HVQA 4ORAA 1V73A 4B2OA 5B8IA 4DSYA 2NXFA 2KKNA 2O8AA 2Z72A 2Q8UA 4FBQA 1Z2XA 1FJMA 3AUZA 3DW8C 3E7BA 3CK2A 3K7WC 1OI8A 4LTYA 5JPFA 2BCDA 1TCOA 2YEQA 2DXLA 5C1VA 1II7A 2IAEC 2IE3C 4LACC 1QFCA 4O24A 5J28A 5EQVA 3QG5C 2IE4C 1IT6A 4LU9A 4V0XA 2NYMC 2P6BA 2WDFA 3GVEA 1WARA 3THOB 2DXNA 4NZVA 3RL3A 3C9FA 1XM7A 3TGHA 1JK7A 4FBKA 2Z06A 4H1SA 3H60A 4ZVZA 3FLOA 4DT2A 3ICFA 4FBWA 4O5GA 4XPNA 3H67A 2ZO9B 1KBPA 2JOGA 4J6OA 3H62B 2CV9A 3ZTVA 4M0VA 4KKZA 3AV0A 4G9JA 3V4YA 3H66A 4DHLA 4IYPC 2BQ8X 3FGAC 3H63A 4V0VA 3H61A 2WDEA 4HD0A 1HP1A 3DSCA 2HY1A 1S3NA 3EGGA 4ZX2A 1SU1A 3RQZA 4JA9A 2AHDA 3QFMA 3QFNA 4UT3B 3THNA 1T70A 5JJTA 3P71C 3E7AA 2QJCA 4O4KA 4WWLA 1Z2WA 2A22A 4FCXA 1S3MA 4JA7A 4H2IA 2ZBMA 4H1YP 2O8GA
chains in the Genus database with same CATH topology
4I5LC 2USHA 5IOHA 2R17A 5F3WA 4I5NC 4UT2A 3PSOA 3K7VC 5JPEA 3LL8A 1OIEA 1G5BA 2BDXA 2GJUA 4H2GA 2HYPA 4KBPA 5GTUA 4UT3A 1T71A 2Z1AA 4YKEA 2WDCA 1S95A 2DFJA 4MOVA 2YVTA 1USHA 3RL4A 3RL5A 1M63A 3PSNA 3DSDA 1U32A 3ZU0A 3EGHA 5DNYA 4H2BA 2QFPA 4F0ZA 1S3LA 2QFRA 1OIDA 1HPUA 3IVEA 4IL1A 4ORCA 1S70A 2ZOAA 2XMOA 3T1IA 3H68A 2HYOA 3E0JA 4O43A 4H2FA 3H64A 4Q7FA 2NPPC 1MF8A 3JYFA 1UF3A 4TUIA 3C5WC 2WDDA 1AUIA 1NNWA 4OR9A 1UTEA 3H69A 4MP0A 4MOYA 4V0WA 4UWQA 3IB8A 2NYLC 1XZWA 1W24A 3KBPA 5INBA 1QHWA 3D03A 5HPEA 4ORBA 1S8EA 1WAO1 3N5UA 3QFOA 3IVDA 3IB7A 4TUGA 3QFKA 1HO5A 3HVQA 4ORAA 1V73A 4B2OA 5B8IA 4DSYA 2NXFA 2KKNA 2O8AA 2Z72A 2Q8UA 4FBQA 1Z2XA 1FJMA 3AUZA 3DW8C 3E7BA 3CK2A 3K7WC 1OI8A 4LTYA 5JPFA 2BCDA 1TCOA 2YEQA 2DXLA 5C1VA 1II7A 2IAEC 2IE3C 4LACC 1QFCA 4O24A 5J28A 5EQVA 3QG5C 2IE4C 1IT6A 4LU9A 4V0XA 2NYMC 2P6BA 2WDFA 3GVEA 1WARA 3THOB 2DXNA 4NZVA 3RL3A 3C9FA 1XM7A 3TGHA 1JK7A 4FBKA 2Z06A 4H1SA 3H60A 4ZVZA 3FLOA 4DT2A 3ICFA 4FBWA 4O5GA 4XPNA 3H67A 2ZO9B 1KBPA 2JOGA 4J6OA 3H62B 2CV9A 3ZTVA 4M0VA 4KKZA 3AV0A 4G9JA 3V4YA 3H66A 4DHLA 4IYPC 2BQ8X 3FGAC 3H63A 4V0VA 3H61A 2WDEA 4HD0A 1HP1A 3DSCA 2HY1A 1S3NA 3EGGA 4ZX2A 1SU1A 3RQZA 4JA9A 2AHDA 3QFMA 3QFNA 4UT3B 3THNA 1T70A 5JJTA 3P71C 3E7AA 2QJCA 4O4KA 4WWLA 1Z2WA 2A22A 4FCXA 1S3MA 4JA7A 4H2IA 2ZBMA 4H1YP 2O8GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4I5L C;  2USH A;  5IOH A;  2R17 A;  5F3W A;  4I5N C;  4UT2 A;  3PSO A;  3K7V C;  5JPE A;  3LL8 A;  1OIE A;  1G5B A;  2BDX A;  2GJU A;  4H2G A;  2HYP A;  4KBP A;  5GTU A;  4UT3 A;  1T71 A;  2Z1A A;  4YKE A;  2WDC A;  1S95 A;  2DFJ A;  4MOV A;  2YVT A;  1USH A;  3RL4 A;  3RL5 A;  1M63 A;  3PSN A;  3DSD A;  1U32 A;  3ZU0 A;  3EGH A;  5DNY A;  4H2B A;  2QFP A;  4F0Z A;  1S3L A;  2QFR A;  1OID A;  1HPU A;  3IVE A;  4IL1 A;  4ORC A;  1S70 A;  2XMO A;  3T1I A;  3H68 A;  2HYO A;  4O43 A;  4H2F A;  3H64 A;  4Q7F A;  2NPP C;  1MF8 A;  3JYF A;  1UF3 A;  4TUI A;  3C5W C;  2WDD A;  1AUI A;  1NNW A;  4OR9 A;  1UTE A;  3H69 A;  4MP0 A;  4MOY A;  4V0W A;  4UWQ A;  3IB8 A;  1XZW A;  2NYL C;  1W24 A;  3KBP A;  5INB A;  1QHW A;  5HPE A;  4ORB A;  1S8E A;  1WAO 1;  3N5U A;  3QFO A;  3IVD A;  3IB7 A;  4TUG A;  3QFK A;  1HO5 A;  3HVQ A;  4ORA A;  1V73 A;  4B2O A;  5B8I A;  4DSY A;  2NXF A;  2KKN A;  2O8A A;  2Z72 A;  2Q8U A;  4FBQ A;  1Z2X A;  1FJM A;  3AUZ A;  3DW8 C;  3E7B A;  3CK2 A;  3K7W C;  1OI8 A;  4LTY A;  5JPF A;  2BCD A;  1TCO A;  5C1V A;  1II7 A;  2IAE C;  2IE3 C;  4LAC C;  1QFC A;  4O24 A;  5J28 A;  5EQV A;  3QG5 C;  2IE4 C;  1IT6 A;  4LU9 A;  4V0X A;  2NYM C;  2P6B A;  2WDF A;  3GVE A;  1WAR A;  3THO B;  4NZV A;  3RL3 A;  3C9F A;  1XM7 A;  3TGH A;  1JK7 A;  4FBK A;  2Z06 A;  4H1S A;  3H60 A;  4ZVZ A;  4DT2 A;  3ICF A;  4FBW A;  4O5G A;  4XPN A;  3H67 A;  1KBP A;  2JOG A;  4J6O A;  3H62 B;  2CV9 A;  3ZTV A;  4M0V A;  4KKZ A;  3AV0 A;  4G9J A;  3V4Y A;  3H66 A;  4DHL A;  4IYP C;  2BQ8 X;  3FGA C;  3H63 A;  4V0V A;  3H61 A;  2WDE A;  4HD0 A;  1HP1 A;  3DSC A;  2HY1 A;  1S3N A;  3EGG A;  4ZX2 A;  1SU1 A;  3RQZ A;  4JA9 A;  2AHD A;  3QFM A;  3QFN A;  4UT3 B;  3THN A;  1T70 A;  5JJT A;  3P71 C;  3E7A A;  2QJC A;  4O4K A;  4WWL A;  1Z2W A;  2A22 A;  4FCX A;  1S3M A;  4JA7 A;  4H2I A;  2ZBM A;  4H1Y P;  2O8G A; 
#chains in the Genus database with same CATH topology
 4I5L C;  2USH A;  5IOH A;  2R17 A;  5F3W A;  4I5N C;  4UT2 A;  3PSO A;  3K7V C;  5JPE A;  3LL8 A;  1OIE A;  1G5B A;  2BDX A;  2GJU A;  4H2G A;  2HYP A;  4KBP A;  5GTU A;  4UT3 A;  1T71 A;  2Z1A A;  4YKE A;  2WDC A;  1S95 A;  2DFJ A;  4MOV A;  2YVT A;  1USH A;  3RL4 A;  3RL5 A;  1M63 A;  3PSN A;  3DSD A;  1U32 A;  3ZU0 A;  3EGH A;  5DNY A;  4H2B A;  2QFP A;  4F0Z A;  1S3L A;  2QFR A;  1OID A;  1HPU A;  3IVE A;  4IL1 A;  4ORC A;  1S70 A;  2ZOA A;  2XMO A;  3T1I A;  3H68 A;  2HYO A;  3E0J A;  4O43 A;  4H2F A;  3H64 A;  4Q7F A;  2NPP C;  1MF8 A;  3JYF A;  1UF3 A;  4TUI A;  3C5W C;  2WDD A;  1AUI A;  1NNW A;  4OR9 A;  1UTE A;  3H69 A;  4MP0 A;  4MOY A;  4V0W A;  4UWQ A;  3IB8 A;  2NYL C;  1XZW A;  1W24 A;  3KBP A;  5INB A;  1QHW A;  3D03 A;  5HPE A;  4ORB A;  1S8E A;  1WAO 1;  3N5U A;  3QFO A;  3IVD A;  3IB7 A;  4TUG A;  3QFK A;  1HO5 A;  3HVQ A;  4ORA A;  1V73 A;  4B2O A;  5B8I A;  4DSY A;  2NXF A;  2KKN A;  2O8A A;  2Z72 A;  2Q8U A;  4FBQ A;  1Z2X A;  1FJM A;  3AUZ A;  3DW8 C;  3E7B A;  3CK2 A;  3K7W C;  1OI8 A;  4LTY A;  5JPF A;  2BCD A;  1TCO A;  2YEQ A;  2DXL A;  5C1V A;  1II7 A;  2IAE C;  2IE3 C;  4LAC C;  1QFC A;  4O24 A;  5J28 A;  5EQV A;  3QG5 C;  2IE4 C;  1IT6 A;  4LU9 A;  4V0X A;  2NYM C;  2P6B A;  2WDF A;  3GVE A;  1WAR A;  3THO B;  2DXN A;  4NZV A;  3RL3 A;  3C9F A;  1XM7 A;  3TGH A;  1JK7 A;  4FBK A;  2Z06 A;  4H1S A;  3H60 A;  4ZVZ A;  3FLO A;  4DT2 A;  3ICF A;  4FBW A;  4O5G A;  4XPN A;  3H67 A;  2ZO9 B;  1KBP A;  2JOG A;  4J6O A;  3H62 B;  2CV9 A;  3ZTV A;  4M0V A;  4KKZ A;  3AV0 A;  4G9J A;  3V4Y A;  3H66 A;  4DHL A;  4IYP C;  2BQ8 X;  3FGA C;  3H63 A;  4V0V A;  3H61 A;  2WDE A;  4HD0 A;  1HP1 A;  3DSC A;  2HY1 A;  1S3N A;  3EGG A;  4ZX2 A;  1SU1 A;  3RQZ A;  4JA9 A;  2AHD A;  3QFM A;  3QFN A;  4UT3 B;  3THN A;  1T70 A;  5JJT A;  3P71 C;  3E7A A;  2QJC A;  4O4K A;  4WWL A;  1Z2W A;  2A22 A;  4FCX A;  1S3M A;  4JA7 A;  4H2I A;  2ZBM A;  4H1Y P;  2O8G A; 
#chains in the Genus database with same CATH homology
 4I5L C;  2USH A;  5IOH A;  2R17 A;  5F3W A;  4I5N C;  4UT2 A;  3PSO A;  3K7V C;  5JPE A;  3LL8 A;  1OIE A;  1G5B A;  2BDX A;  2GJU A;  4H2G A;  2HYP A;  4KBP A;  5GTU A;  4UT3 A;  1T71 A;  2Z1A A;  4YKE A;  2WDC A;  1S95 A;  2DFJ A;  4MOV A;  2YVT A;  1USH A;  3RL4 A;  3RL5 A;  1M63 A;  3PSN A;  3DSD A;  1U32 A;  3ZU0 A;  3EGH A;  5DNY A;  4H2B A;  2QFP A;  4F0Z A;  1S3L A;  2QFR A;  1OID A;  1HPU A;  3IVE A;  4IL1 A;  4ORC A;  1S70 A;  2ZOA A;  2XMO A;  3T1I A;  3H68 A;  2HYO A;  3E0J A;  4O43 A;  4H2F A;  3H64 A;  4Q7F A;  2NPP C;  1MF8 A;  3JYF A;  1UF3 A;  4TUI A;  3C5W C;  2WDD A;  1AUI A;  1NNW A;  4OR9 A;  1UTE A;  3H69 A;  4MP0 A;  4MOY A;  4V0W A;  4UWQ A;  3IB8 A;  2NYL C;  1XZW A;  1W24 A;  3KBP A;  5INB A;  1QHW A;  3D03 A;  5HPE A;  4ORB A;  1S8E A;  1WAO 1;  3N5U A;  3QFO A;  3IVD A;  3IB7 A;  4TUG A;  3QFK A;  1HO5 A;  3HVQ A;  4ORA A;  1V73 A;  4B2O A;  5B8I A;  4DSY A;  2NXF A;  2KKN A;  2O8A A;  2Z72 A;  2Q8U A;  4FBQ A;  1Z2X A;  1FJM A;  3AUZ A;  3DW8 C;  3E7B A;  3CK2 A;  3K7W C;  1OI8 A;  4LTY A;  5JPF A;  2BCD A;  1TCO A;  2YEQ A;  2DXL A;  5C1V A;  1II7 A;  2IAE C;  2IE3 C;  4LAC C;  1QFC A;  4O24 A;  5J28 A;  5EQV A;  3QG5 C;  2IE4 C;  1IT6 A;  4LU9 A;  4V0X A;  2NYM C;  2P6B A;  2WDF A;  3GVE A;  1WAR A;  3THO B;  2DXN A;  4NZV A;  3RL3 A;  3C9F A;  1XM7 A;  3TGH A;  1JK7 A;  4FBK A;  2Z06 A;  4H1S A;  3H60 A;  4ZVZ A;  3FLO A;  4DT2 A;  3ICF A;  4FBW A;  4O5G A;  4XPN A;  3H67 A;  2ZO9 B;  1KBP A;  2JOG A;  4J6O A;  3H62 B;  2CV9 A;  3ZTV A;  4M0V A;  4KKZ A;  3AV0 A;  4G9J A;  3V4Y A;  3H66 A;  4DHL A;  4IYP C;  2BQ8 X;  3FGA C;  3H63 A;  4V0V A;  3H61 A;  2WDE A;  4HD0 A;  1HP1 A;  3DSC A;  2HY1 A;  1S3N A;  3EGG A;  4ZX2 A;  1SU1 A;  3RQZ A;  4JA9 A;  2AHD A;  3QFM A;  3QFN A;  4UT3 B;  3THN A;  1T70 A;  5JJT A;  3P71 C;  3E7A A;  2QJC A;  4O4K A;  4WWL A;  1Z2W A;  2A22 A;  4FCX A;  1S3M A;  4JA7 A;  4H2I A;  2ZBM A;  4H1Y P;  2O8G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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