5JVG1

The large ribosomal subunit from deinococcus radiodurans in complex with avilamycin
Total Genus 2
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
2
sequence length
53
structure length
53
Chain Sequence
AKDGPRIIVKMESSAGTGFYYTTTKNRRNTQAKLELKKYDPVAKKHVVFREKK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Avilamycin and evernimicin induce structural changes in rProteins uL16 and CTC that enhance the inhibition of A-site tRNA binding.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S ribosomal RNA
total genus 2
structure length 53
sequence length 53
ec nomenclature
pdb deposition date 2016-05-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
1 PF00471 Ribosomal_L33 Ribosomal protein L33
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.120 Mainly Beta Single Sheet Rubrerythrin, domain 2 Rubrerythrin, domain 2 5jvg100
4V196 5DM71 3J7Y1 5MLC3 5GADc 4U671 5H1Sc 5DM61 5GAGc 5GAHc 3J7Z1 5GAEc 5JVG1 4WFN1 3PIO1 3PIP1 4UY81 5JVH1
chains in the Genus database with same CATH superfamily
1LTLA 1C09A 4AR4A 3PO2L 2NVTL 3PIP1 2WB1P 3RZ6A 3LWOB 1I3QL 3LPEB 1IU6A 4Y52L 4XGHA 4POGA 5MFZA 3H9BA 3HKZP 4JAFA 4TPUA 5JVH1 4ME3A 4A3EL 2V0EA 3HOWL 2YU9L 3H97A 4YWLA 1ZRPA 3GTGL 3J7Y1 2WAQP 5DM61 5GAEc 4UY81 3NFPI 3KYUA 1SMUA 2NYDA 1TWAL 5MGNA 4A3KL 1VCXA 8RXNA 5RXNA 2MS3A 2A6HD 4XXBB 3S2DL 1JYBA 3LWPB 2L0ZA 2PVXA 4AR5A 2JA6L 4A3IL 1IU5A 4TVMA 4JAGA 3HOYL 4X6AL 1F4LA 4AR3A 1VZGA 4A3FL 2E2IL 3PO3L 2HVYC 1IROA 2PVEA 1SFOL 2B5ID 1VZHA 1T9PA 2PSMC 1R0JA 3RZTA 3GTQL 2KKDA 3H9CA 2XJPA 3LNLA 3P2AA 3VPBE 4A3DL 3GTLL 4AYBP 1IW7D 4AI0A 1B13A 4JAEA 4K9FA 4Y7NL 3LWVB 1T9OA 1WCML 3MSUA 2VUML 1BE7A 5IYCL 3J7Z1 5M3FL 1B71A 7RXNA 3B08B 4ZN1B 1BFYA 4A3LL 1SMWA 1Y1VL 1PFUA 2XJSA 4BBSL 3RZOL 4BY1L 1R0HA 1PFWA 1RDGA 1B2OA 3ZG6A 3HAXC 4A3GL 1RYTA 2KN9A 2NVXL 3JR7A 3KYWA 4AHYA 3S15L 1WJVA 3KYYA 3HOXL 5C4JL 2Y0SP 3PZAA 2E2JL 1RB9A 3H99A 3K35A 2PPTA 2EY4E 3S1NL 4AR6A 1YV1A 3KYVA 3B0AB 2JA7L 5GADc 2CKCA 1BQ9A 3IU3I 3MPSA 3M4OL 3S1ML 1FHMA 1TWGL 2LCQA 1CAAA 2JI3A 1NXGA 3RYGA 2R92L 4E6YA 2M4YA 4G6BA 4AHXA 3HOZL 1TWFL 5EIOC 3WWLA 3PIO1 2J9UB 1R0GA 3LWRB 1YUZA 1LKOA 2VL6A 1CADA 2C6BA 2BE5D 4U671 3S16L 3S14L 1T9QA 1BRFA 2NVYL 1Y1WL 1IRNA 5IP9L 1LKPA 5C3EL 3MQKB 1YUXA 1LKMA 5IP7L 2V0FA 4A3BL 1B2JA 3P8BA 4QIWP 2XJRA 5AI3A 4AHWA 3S1QL 1TWCL 2A68D 1YK5A 1SMMA 3QQCE 2NVQL 1QCVA 1Z92B 1OWCA 2JA8L 4AI3A 4WFN1 4BBRL 3HJWB 2AYJA 4B8CD 1R9TL 1DVBA 3KYXA 2M6OA 3CQZL 3GTJL 4V196 5AI2A 5AN9H 4AHZA 2XJVA 4LHLA 3FKIL 5C4XL 1QYBA 2DSXA 1QQTA 4GS7D 4C3IL 5DM71 2M6PA 2CKAA 2ERJA 5IY0A 5C44L 2JI2A 2AUSB 1PFVA 1RWDA 3GTPL 1RDVA 3PWFA 1DX8A 2ERSA 3SS2A 2JA5L 5M5YL 5JVG1 3RZDL 5IYDL 2R7ZL 4LHNA 5IYBL 2A6ED 4A3JL 1K83L 6RXNA 4ZN3B 1I50L 1R0FA 4A93L 2APOB 5FJ8L 5GAGc 3A44A 2H12A 2V3BB 1RYQA 3M3YL 2K2DA 2PMZP 1TWHL 2PYAA 1OWBA 4JADA 1I6HL 3LWQB 2GMGA 3GTML 3GTKL 1BQ8A 4A3CL 1VZIA 2XJUA 1PFYA 2AQCA 2E2HL 2RDVA 1NNQA 2QL0A 2M4VA 2C6AA 4AI1A 5GAHc 3S17L 1NXEA 2ZIXA 4AI2A 4BY7L 2RFKB 3K7AL 2B63L 2CR8A 3GTOL 3H0GL 4C3HL 2Z3QB 5M3ML 1S30A 3PL5A 4A3ML 1R0IA 5M5XL 3PKJA 4C3JL 3QVDA 3H3VM 4C2M1 3HJYB 4RXNA 1FHHA 1PZXA 2Z3RB 1S24A 1H7VA 3HOUL 5MLC3 5FLML 1P7PA 3FDJA 2XJQA 5K2ME 1YK4A 2HR5A 5EINC 3I4ML 3WWNB 3I4NL 2A69D 3PKIA 3HOVL 4POFA 1E8JA 2R93L 2XJTA 5MF6A 5M5WL 5MFPA 4BXXL 5H1Sc 3S2HL 1S2ZA 3S1RL 2O5JD 2JI1A 4YWMA 1ODHA
chains in the Genus database with same CATH topology
1YUXA 1LTLA 1C09A 1LKMA 1RYQA 4AR4A 2V0FA 3J7Z1 3PIP1 1B71A 7RXNA 1B2JA 2K2DA 3P8BA 3B08B 2XJRA 4ZN1B 5AI3A 2PYAA 1BFYA 1OWBA 4JADA 3RZ6A 1SMWA 4AHWA 2A68D 2XJSA 2GMGA 3LPEB 1YK5A 1IU6A 1SMMA 4XGHA 1BQ8A 4POGA 5MFZA 4JAFA 1VZIA 1R0HA 2XJUA 3QQCE 1RDGA 4TPUA 1B2OA 1QCVA 1Z92B 3ZG6A 5JVH1 2RDVA 1OWCA 1NNQA 1RYTA 2M4VA 2QL0A 2C6AA 2KN9A 4AI1A 5GAHc 4ME3A 4AI3A 4WFN1 1NXEA 2V0EA 2ZIXA 4AI2A 2AYJA 3KYWA 4AHYA 4B8CD 1DVBA 3KYXA 1WJVA 2M6OA 3KYYA 4YWLA 2CR8A 1ZRPA 3PZAA 1RB9A 4V196 2Z3QB 3K35A 5AI2A 1S30A 2PPTA 3J7Y1 5DM61 5AN9H 4AR6A 4AHZA 5GAEc 2XJVA 3NFPI 1YV1A 3KYVA 3B0AB 3KYUA 4LHLA 1R0IA 1SMUA 4UY81 1QYBA 2NYDA 2DSXA 3PKJA 2CKCA 1BQ9A 5GADc 5MGNA 1VCXA 3IU3I 3MPSA 4GS7D 8RXNA 5RXNA 2MS3A 2A6HD 1FHMA 4XXBB 2LCQA 1CAAA 5DM71 2M6PA 2CKAA 1JYBA 2JI3A 1NXGA 3QVDA 3RYGA 2ERJA 2L0ZA 2PVXA 4AR5A 5IY0A 4E6YA 2M4YA 4G6BA 4AHXA 4RXNA 3WWLA 1FHHA 2Z3RB 2J9UB 1S24A 5EIOC 3PIO1 2JI2A 1H7VA 5MLC3 1IU5A 4TVMA 1R0GA 1YUZA 4JAGA 1RWDA 2XJQA 5K2ME 1LKOA 1YK4A 4AR3A 2HR5A 2VL6A 1RDVA 3PWFA 5EINC 1DX8A 1VZGA 1CADA 2ERSA 2C6BA 3SS2A 3WWNB 1IROA 2PVEA 2B5ID 1VZHA 2A69D 3PKIA 1T9PA 5JVG1 4LHNA 2PSMC 1R0JA 4POFA 3RZTA 1E8JA 2BE5D 2XJTA 5MF6A 2KKDA 3LNLA 2A6ED 2XJPA 4U671 5MFPA 3P2AA 6RXNA 3VPBE 4ZN3B 1T9QA 1BRFA 1IW7D 1IRNA 1R0FA 5H1Sc 4AI0A 1B13A 1S2ZA 4JAEA 1LKPA 4K9FA 2O5JD 2JI1A 5GAGc 3A44A 1T9OA 3MSUA 2H12A 4YWMA 2V3BB 1ODHA 1BE7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4V19 6;  5DM7 1;  3J7Y 1;  5MLC 3;  5GAD c;  4U67 1;  5H1S c;  5DM6 1;  5GAG c;  5GAH c;  3J7Z 1;  5GAE c;  5JVG 1;  4WFN 1;  3PIO 1;  3PIP 1;  4UY8 1;  5JVH 1; 
#chains in the Genus database with same CATH topology
 1LTL A;  1C09 A;  4AR4 A;  3PO2 L;  2NVT L;  3PIP 1;  2WB1 P;  3RZ6 A;  3LWO B;  1I3Q L;  3LPE B;  1IU6 A;  4Y52 L;  4XGH A;  4POG A;  5MFZ A;  3H9B A;  3HKZ P;  4JAF A;  4TPU A;  5JVH 1;  4ME3 A;  4A3E L;  2V0E A;  3HOW L;  2YU9 L;  3H97 A;  4YWL A;  1ZRP A;  3GTG L;  3J7Y 1;  2WAQ P;  5DM6 1;  5GAE c;  4UY8 1;  3NFP I;  3KYU A;  1SMU A;  2NYD A;  1TWA L;  5MGN A;  4A3K L;  1VCX A;  8RXN A;  5RXN A;  2MS3 A;  2A6H D;  4XXB B;  3S2D L;  1JYB A;  3LWP B;  2L0Z A;  2PVX A;  4AR5 A;  2JA6 L;  4A3I L;  1IU5 A;  4TVM A;  4JAG A;  3HOY L;  4X6A L;  1F4L A;  4AR3 A;  1VZG A;  4A3F L;  2E2I L;  3PO3 L;  2HVY C;  1IRO A;  2PVE A;  1SFO L;  2B5I D;  1VZH A;  1T9P A;  2PSM C;  1R0J A;  3RZT A;  3GTQ L;  2KKD A;  3H9C A;  2XJP A;  3LNL A;  3P2A A;  3VPB E;  4A3D L;  3GTL L;  4AYB P;  1IW7 D;  4AI0 A;  1B13 A;  4JAE A;  4K9F A;  4Y7N L;  3LWV B;  1T9O A;  1WCM L;  3MSU A;  2VUM L;  1BE7 A;  5IYC L;  3J7Z 1;  5M3F L;  1B71 A;  7RXN A;  3B08 B;  4ZN1 B;  1BFY A;  4A3L L;  1SMW A;  1Y1V L;  1PFU A;  2XJS A;  4BBS L;  3RZO L;  4BY1 L;  1R0H A;  1PFW A;  1RDG A;  1B2O A;  3ZG6 A;  3HAX C;  4A3G L;  1RYT A;  2KN9 A;  2NVX L;  3JR7 A;  3KYW A;  4AHY A;  3S15 L;  1WJV A;  3KYY A;  3HOX L;  5C4J L;  2Y0S P;  3PZA A;  2E2J L;  1RB9 A;  3H99 A;  3K35 A;  2PPT A;  2EY4 E;  3S1N L;  4AR6 A;  1YV1 A;  3KYV A;  3B0A B;  2JA7 L;  5GAD c;  2CKC A;  1BQ9 A;  3IU3 I;  3MPS A;  3M4O L;  3S1M L;  1FHM A;  1TWG L;  2LCQ A;  1CAA A;  2JI3 A;  1NXG A;  3RYG A;  2R92 L;  4E6Y A;  2M4Y A;  4G6B A;  4AHX A;  3HOZ L;  1TWF L;  5EIO C;  3WWL A;  3PIO 1;  2J9U B;  1R0G A;  3LWR B;  1YUZ A;  1LKO A;  2VL6 A;  1CAD A;  2C6B A;  2BE5 D;  4U67 1;  3S16 L;  3S14 L;  1T9Q A;  1BRF A;  2NVY L;  1Y1W L;  1IRN A;  5IP9 L;  1LKP A;  5C3E L;  3MQK B;  1YUX A;  1LKM A;  5IP7 L;  2V0F A;  4A3B L;  1B2J A;  3P8B A;  4QIW P;  2XJR A;  5AI3 A;  4AHW A;  3S1Q L;  1TWC L;  2A68 D;  1YK5 A;  1SMM A;  3QQC E;  2NVQ L;  1QCV A;  1Z92 B;  1OWC A;  2JA8 L;  4AI3 A;  4WFN 1;  4BBR L;  3HJW B;  2AYJ A;  4B8C D;  1R9T L;  1DVB A;  3KYX A;  2M6O A;  3CQZ L;  3GTJ L;  4V19 6;  5AI2 A;  5AN9 H;  4AHZ A;  2XJV A;  4LHL A;  3FKI L;  5C4X L;  1QYB A;  2DSX A;  1QQT A;  4GS7 D;  4C3I L;  5DM7 1;  2M6P A;  2CKA A;  2ERJ A;  5IY0 A;  5C44 L;  2JI2 A;  2AUS B;  1PFV A;  1RWD A;  3GTP L;  1RDV A;  3PWF A;  1DX8 A;  2ERS A;  3SS2 A;  2JA5 L;  5M5Y L;  5JVG 1;  3RZD L;  5IYD L;  2R7Z L;  4LHN A;  5IYB L;  2A6E D;  4A3J L;  1K83 L;  6RXN A;  4ZN3 B;  1I50 L;  1R0F A;  4A93 L;  2APO B;  5FJ8 L;  5GAG c;  3A44 A;  2H12 A;  2V3B B;  1RYQ A;  3M3Y L;  2K2D A;  2PMZ P;  1TWH L;  2PYA A;  1OWB A;  4JAD A;  1I6H L;  3LWQ B;  2GMG A;  3GTM L;  3GTK L;  1BQ8 A;  4A3C L;  1VZI A;  2XJU A;  1PFY A;  2AQC A;  2E2H L;  2RDV A;  1NNQ A;  2QL0 A;  2M4V A;  2C6A A;  4AI1 A;  5GAH c;  3S17 L;  1NXE A;  2ZIX A;  4AI2 A;  4BY7 L;  2RFK B;  3K7A L;  2B63 L;  2CR8 A;  3GTO L;  3H0G L;  4C3H L;  2Z3Q B;  5M3M L;  1S30 A;  3PL5 A;  4A3M L;  1R0I A;  5M5X L;  3PKJ A;  4C3J L;  3QVD A;  3H3V M;  4C2M 1;  3HJY B;  4RXN A;  1FHH A;  1PZX A;  2Z3R B;  1S24 A;  1H7V A;  3HOU L;  5MLC 3;  5FLM L;  1P7P A;  3FDJ A;  2XJQ A;  5K2M E;  1YK4 A;  2HR5 A;  5EIN C;  3I4M L;  3WWN B;  3I4N L;  2A69 D;  3PKI A;  3HOV L;  4POF A;  1E8J A;  2R93 L;  2XJT A;  5MF6 A;  5M5W L;  5MFP A;  4BXX L;  5H1S c;  3S2H L;  1S2Z A;  3S1R L;  2O5J D;  2JI1 A;  4YWM A;  1ODH A; 
#chains in the Genus database with same CATH homology
 1YUX A;  1LTL A;  1C09 A;  1LKM A;  1RYQ A;  4AR4 A;  2V0F A;  3J7Z 1;  3PIP 1;  1B71 A;  7RXN A;  1B2J A;  2K2D A;  3P8B A;  3B08 B;  2XJR A;  4ZN1 B;  5AI3 A;  2PYA A;  1BFY A;  1OWB A;  4JAD A;  3RZ6 A;  1SMW A;  4AHW A;  2A68 D;  2XJS A;  2GMG A;  3LPE B;  1YK5 A;  1IU6 A;  1SMM A;  4XGH A;  1BQ8 A;  4POG A;  5MFZ A;  4JAF A;  1VZI A;  1R0H A;  2XJU A;  3QQC E;  1RDG A;  4TPU A;  1B2O A;  1QCV A;  1Z92 B;  3ZG6 A;  5JVH 1;  2RDV A;  1OWC A;  1NNQ A;  1RYT A;  2M4V A;  2QL0 A;  2C6A A;  2KN9 A;  4AI1 A;  5GAH c;  4ME3 A;  4AI3 A;  4WFN 1;  1NXE A;  2V0E A;  2ZIX A;  4AI2 A;  2AYJ A;  3KYW A;  4AHY A;  4B8C D;  1DVB A;  3KYX A;  1WJV A;  2M6O A;  3KYY A;  4YWL A;  2CR8 A;  1ZRP A;  3PZA A;  1RB9 A;  4V19 6;  2Z3Q B;  3K35 A;  5AI2 A;  1S30 A;  2PPT A;  3J7Y 1;  5DM6 1;  5AN9 H;  4AR6 A;  4AHZ A;  5GAE c;  2XJV A;  3NFP I;  1YV1 A;  3KYV A;  3B0A B;  3KYU A;  4LHL A;  1R0I A;  1SMU A;  4UY8 1;  1QYB A;  2NYD A;  2DSX A;  3PKJ A;  2CKC A;  1BQ9 A;  5GAD c;  5MGN A;  1VCX A;  3IU3 I;  3MPS A;  4GS7 D;  8RXN A;  5RXN A;  2MS3 A;  2A6H D;  1FHM A;  4XXB B;  2LCQ A;  1CAA A;  5DM7 1;  2M6P A;  2CKA A;  1JYB A;  2JI3 A;  1NXG A;  3QVD A;  3RYG A;  2ERJ A;  2L0Z A;  2PVX A;  4AR5 A;  5IY0 A;  4E6Y A;  2M4Y A;  4G6B A;  4AHX A;  4RXN A;  3WWL A;  1FHH A;  2Z3R B;  2J9U B;  1S24 A;  5EIO C;  3PIO 1;  2JI2 A;  1H7V A;  5MLC 3;  1IU5 A;  4TVM A;  1R0G A;  1YUZ A;  4JAG A;  1RWD A;  2XJQ A;  5K2M E;  1LKO A;  1YK4 A;  4AR3 A;  2HR5 A;  2VL6 A;  1RDV A;  3PWF A;  5EIN C;  1DX8 A;  1VZG A;  1CAD A;  2ERS A;  2C6B A;  3SS2 A;  3WWN B;  1IRO A;  2PVE A;  2B5I D;  1VZH A;  2A69 D;  3PKI A;  1T9P A;  5JVG 1;  4LHN A;  2PSM C;  1R0J A;  4POF A;  3RZT A;  1E8J A;  2BE5 D;  2XJT A;  5MF6 A;  2KKD A;  3LNL A;  2A6E D;  2XJP A;  4U67 1;  5MFP A;  3P2A A;  6RXN A;  3VPB E;  4ZN3 B;  1T9Q A;  1BRF A;  1IW7 D;  1IRN A;  1R0F A;  5H1S c;  4AI0 A;  1B13 A;  1S2Z A;  4JAE A;  1LKP A;  4K9F A;  2O5J D;  2JI1 A;  5GAG c;  3A44 A;  1T9O A;  3MSU A;  2H12 A;  4YWM A;  2V3B B;  1ODH A;  1BE7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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