5JVH1

The crystal structure large ribosomal subunit (50s) of deinococcus radiodurans in complex with evernimicin
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
53
structure length
53
Chain Sequence
AKDGPRIIVKMESSAGTGFYYTTTKNRRNTQAKLELKKYDPVAKKHVVFREKK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Avilamycin and evernimicin induce structural changes in rProteins uL16 and CTC that enhance the inhibition of A-site tRNA binding.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S ribosomal RNA
total genus 3
structure length 53
sequence length 53
ec nomenclature
pdb deposition date 2016-05-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
1 PF00471 Ribosomal_L33 Ribosomal protein L33
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.120 Mainly Beta Single Sheet Rubrerythrin, domain 2 Rubrerythrin, domain 2 5jvh100
4WFN1 5GADc 5GAEc 3PIP1 4V196 5DM71 5MLC3 5H1Sc 4U671 5JVG1 4UY81 5GAHc 3J7Z1 3PIO1 5JVH1 5DM61 3J7Y1 5GAGc
chains in the Genus database with same CATH superfamily
1QYBA 1IW7D 5M5XL 5GAEc 3S1ML 1B13A 3S16L 4AHWA 5MF6A 2NVQL 1PFWA 3H9BA 1B71A 5AN9H 2M6PA 5EIOC 1LKPA 1T9PA 3PZAA 2VUML 4A93L 1CAAA 2XJTA 1RDGA 2V0FA 1PFVA 2GMGA 1VCXA 1BRFA 1TWGL 2PMZP 2C6BA 2ZIXA 2PVXA 3QVDA 4LHNA 2B5ID 1YK4A 5M5WL 2Z3QB 2WB1P 1RDVA 2NVYL 1Z92B 4A3ML 3I4ML 1RB9A 2CR8A 4TPUA 3H9CA 4JAEA 4A3KL 1YV1A 2JI2A 1T9QA 1R0IA 3LWQB 4XXBB 4AI2A 2NVTL 1SMWA 3RZTA 4A3CL 2RFKB 5AI2A 3KYXA 3FDJA 3LWVB 3I4NL 3MSUA 5RXNA 1CADA 2XJPA 3K7AL 4A3LL 5DM71 5MLC3 2AQCA 3HAXC 3J7Y1 1R9TL 4ZN1B 4BY7L 3GTKL 1P7PA 5M5YL 1I50L 1B2JA 2J9UB 2QL0A 3LPEB 1YUXA 4AI0A 2XJQA 5EINC 3HJYB 5K2ME 1QQTA 1S24A 1RWDA 3RZDL 1R0FA 4A3IL 4AYBP 4YWMA 4K9FA 1LTLA 2XJVA 1I6HL 2H12A 5C4JL 1R0GA 1VZIA 3S2DL 4C3IL 2PPTA 2Y0SP 1BQ9A 5DM61 2KN9A 2R93L 3P8BA 3GTOL 4QIWP 4B8CD 3KYYA 3HKZP 2EY4E 1OWCA 2WAQP 3LWOB 2A6ED 3LNLA 1Y1WL 1C09A 3KYVA 4BXXL 4Y52L 3PKIA 2E2JL 3RZOL 5GADc 1TWHL 4U671 3WWNB 1RYTA 1PFYA 3QQCE 1IU6A 1NNQA 4AHXA 5FLML 1OWBA 2AYJA 4BY1L 5FJ8L 2XJRA 2Z3RB 3B0AB 1R0HA 3LWPB 3S2HL 3PIP1 3PL5A 4POFA 2C6AA 5JVH1 2V0EA 2O5JD 1B2OA 6RXNA 3HJWB 2JI1A 1IU5A 3SS2A 3PO2L 3HOWL 3GTPL 3GTJL 1SFOL 3S1RL 1IROA 3LWRB 4AHYA 4JADA 2RDVA 1LKMA 5C4XL 1TWAL 4A3BL 2KKDA 2CKCA 5IYBL 3S1NL 1NXGA 5IYDL 3HOZL 5IY0A 4AR4A 1TWFL 4C3HL 3H3VM 4YWLA 1LKOA 4X6AL 1VZHA 2XJSA 3JR7A 1BFYA 4UY81 2ERJA 4AI3A 2JA8L 4A3GL 3MPSA 4AR3A 4A3DL 4E6YA 3KYWA 3M3YL 3H99A 2JA6L 4ME3A 4AI1A 4JAFA 1DVBA 4JAGA 3IU3I 3P2AA 2JA7L 2HR5A 4G6BA 4RXNA 2R7ZL 3S15L 3HOYL 1K83L 3K35A 3VPBE 3H97A 1SMUA 5M3FL 5H1Sc 5JVG1 3PIO1 1Y1VL 1NXEA 4Y7NL 2E2HL 2DSXA 4A3FL 3ZG6A 5C44L 1WCML 3HOVL 2E2IL 3H0GL 2V3BB 1E8JA 3J7Z1 1FHMA 4A3EL 4XGHA 1QCVA 2B63L 3M4OL 3PO3L 3GTQL 3RZ6A 2JA5L 1H7VA 2YU9L 3WWLA 2R92L 1IRNA 2PSMC 5GAGc 4WFN1 4C3JL 2PVEA 2A69D 8RXNA 3GTGL 3PWFA 5GAHc 3GTML 5MFZA 2A68D 2NVXL 4AR6A 3A44A 1JYBA 3RYGA 2JI3A 1WJVA 5IYCL 1ZRPA 1F4LA 5IP7L 1BQ8A 1ODHA 7RXNA 2M4YA 4LHLA 1I3QL 1S30A 1BE7A 2BE5D 2L0ZA 2PYAA 3B08B 2APOB 3HOXL 5C3EL 1SMMA 3FKIL 2CKAA 1DX8A 3KYUA 2XJUA 3PKJA 1VZGA 1YK5A 1PZXA 4V196 4BBSL 2M6OA 2MS3A 3S14L 1TWCL 1R0JA 2HVYC 4ZN3B 2K2DA 4TVMA 5M3ML 4C2M1 5MGNA 4AR5A 2VL6A 1YUZA 5AI3A 3HOUL 2M4VA 2AUSB 3S1QL 2NYDA 4AHZA 4POGA 4BBRL 4A3JL 2A6HD 1T9OA 1RYQA 3CQZL 3S17L 5IP9L 4GS7D 1FHHA 2LCQA 3MQKB 1PFUA 3NFPI 1S2ZA 5MFPA 2ERSA 3GTLL
chains in the Genus database with same CATH topology
1QYBA 1IW7D 5GAEc 1H7VA 2JI1A 1IU5A 3WWLA 3SS2A 1IRNA 2PSMC 5GAGc 1B2JA 2J9UB 2QL0A 3LPEB 4WFN1 2PVEA 1B13A 1YUXA 4AI0A 2XJQA 2A69D 1IROA 8RXNA 4AHYA 4JADA 5EINC 2RDVA 4AHWA 5MF6A 3PWFA 1LKMA 5K2ME 5GAHc 1S24A 5MFZA 1RWDA 2A68D 4AR6A 3A44A 1JYBA 2KKDA 2CKCA 3RYGA 1R0FA 1B71A 2JI3A 4YWMA 4K9FA 1WJVA 1ZRPA 1LTLA 5AN9H 1NXGA 2M6PA 5EIOC 2XJVA 2H12A 1LKPA 1T9PA 3PZAA 5IY0A 1BQ8A 1ODHA 4AR4A 1R0GA 1VZIA 4YWLA 7RXNA 2M4YA 4LHLA 1LKOA 1S30A 1BE7A 1CAAA 2BE5D 2L0ZA 2PYAA 1VZHA 2XJSA 2XJTA 1BFYA 4UY81 2PPTA 1RDGA 2ERJA 2V0FA 3B08B 4AI3A 3MPSA 1BQ9A 2GMGA 1SMMA 2KN9A 5DM61 3P8BA 1VCXA 4AR3A 2CKAA 1BRFA 4E6YA 1DX8A 3KYUA 3KYWA 4B8CD 3KYYA 2C6BA 2XJUA 3PKJA 1VZGA 2ZIXA 1YK5A 2PVXA 1OWCA 4ME3A 4AI1A 3QVDA 4JAFA 1DVBA 4JAGA 4LHNA 3IU3I 3P2AA 2B5ID 4V196 1YK4A 2A6ED 2Z3QB 2M6OA 1RDVA 3LNLA 1Z92B 2HR5A 4G6BA 4RXNA 1C09A 2MS3A 1RB9A 1R0JA 3KYVA 2CR8A 4ZN3B 4TPUA 2K2DA 3PKIA 4TVMA 3K35A 3VPBE 4JAEA 5GADc 5MGNA 1YV1A 1SMUA 4AR5A 2VL6A 5H1Sc 1YUZA 5AI3A 2JI2A 1T9QA 1R0IA 2M4VA 4U671 4XXBB 4AI2A 5JVG1 3WWNB 1RYTA 3PIO1 1SMWA 3RZTA 3QQCE 1NXEA 1IU6A 2NYDA 1NNQA 4AHZA 4AHXA 2DSXA 1OWBA 5AI2A 2AYJA 3KYXA 3ZG6A 2XJRA 2Z3RB 3B0AB 1R0HA 4POGA 2A6HD 1T9OA 3MSUA 1RYQA 5RXNA 1CADA 2XJPA 3PIP1 5DM71 5MLC3 2V3BB 4GS7D 1FHHA 2LCQA 4POFA 3J7Z1 2C6AA 1FHMA 5JVH1 1E8JA 3J7Y1 2V0EA 2O5JD 1B2OA 3NFPI 1QCVA 4XGHA 4ZN1B 1S2ZA 6RXNA 5MFPA 2ERSA 3RZ6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WFN 1;  5GAD c;  5GAE c;  3PIP 1;  4V19 6;  5DM7 1;  5MLC 3;  5H1S c;  4U67 1;  5JVG 1;  4UY8 1;  5GAH c;  3J7Z 1;  3PIO 1;  5JVH 1;  5DM6 1;  3J7Y 1;  5GAG c; 
#chains in the Genus database with same CATH topology
 1QYB A;  1IW7 D;  5M5X L;  5GAE c;  3S1M L;  1B13 A;  3S16 L;  4AHW A;  5MF6 A;  2NVQ L;  1PFW A;  3H9B A;  1B71 A;  5AN9 H;  2M6P A;  5EIO C;  1LKP A;  1T9P A;  3PZA A;  2VUM L;  4A93 L;  1CAA A;  2XJT A;  1RDG A;  2V0F A;  1PFV A;  2GMG A;  1VCX A;  1BRF A;  1TWG L;  2PMZ P;  2C6B A;  2ZIX A;  2PVX A;  3QVD A;  4LHN A;  2B5I D;  1YK4 A;  5M5W L;  2Z3Q B;  2WB1 P;  1RDV A;  2NVY L;  1Z92 B;  4A3M L;  3I4M L;  1RB9 A;  2CR8 A;  4TPU A;  3H9C A;  4JAE A;  4A3K L;  1YV1 A;  2JI2 A;  1T9Q A;  1R0I A;  3LWQ B;  4XXB B;  4AI2 A;  2NVT L;  1SMW A;  3RZT A;  4A3C L;  2RFK B;  5AI2 A;  3KYX A;  3FDJ A;  3LWV B;  3I4N L;  3MSU A;  5RXN A;  1CAD A;  2XJP A;  3K7A L;  4A3L L;  5DM7 1;  5MLC 3;  2AQC A;  3HAX C;  3J7Y 1;  1R9T L;  4ZN1 B;  4BY7 L;  3GTK L;  1P7P A;  5M5Y L;  1I50 L;  1B2J A;  2J9U B;  2QL0 A;  3LPE B;  1YUX A;  4AI0 A;  2XJQ A;  5EIN C;  3HJY B;  5K2M E;  1QQT A;  1S24 A;  1RWD A;  3RZD L;  1R0F A;  4A3I L;  4AYB P;  4YWM A;  4K9F A;  1LTL A;  2XJV A;  1I6H L;  2H12 A;  5C4J L;  1R0G A;  1VZI A;  3S2D L;  4C3I L;  2PPT A;  2Y0S P;  1BQ9 A;  5DM6 1;  2KN9 A;  2R93 L;  3P8B A;  3GTO L;  4QIW P;  4B8C D;  3KYY A;  3HKZ P;  2EY4 E;  1OWC A;  2WAQ P;  3LWO B;  2A6E D;  3LNL A;  1Y1W L;  1C09 A;  3KYV A;  4BXX L;  4Y52 L;  3PKI A;  2E2J L;  3RZO L;  5GAD c;  1TWH L;  4U67 1;  3WWN B;  1RYT A;  1PFY A;  3QQC E;  1IU6 A;  1NNQ A;  4AHX A;  5FLM L;  1OWB A;  2AYJ A;  4BY1 L;  5FJ8 L;  2XJR A;  2Z3R B;  3B0A B;  1R0H A;  3LWP B;  3S2H L;  3PIP 1;  3PL5 A;  4POF A;  2C6A A;  5JVH 1;  2V0E A;  2O5J D;  1B2O A;  6RXN A;  3HJW B;  2JI1 A;  1IU5 A;  3SS2 A;  3PO2 L;  3HOW L;  3GTP L;  3GTJ L;  1SFO L;  3S1R L;  1IRO A;  3LWR B;  4AHY A;  4JAD A;  2RDV A;  1LKM A;  5C4X L;  1TWA L;  4A3B L;  2KKD A;  2CKC A;  5IYB L;  3S1N L;  1NXG A;  5IYD L;  3HOZ L;  5IY0 A;  4AR4 A;  1TWF L;  4C3H L;  3H3V M;  4YWL A;  1LKO A;  4X6A L;  1VZH A;  2XJS A;  3JR7 A;  1BFY A;  4UY8 1;  2ERJ A;  4AI3 A;  2JA8 L;  4A3G L;  3MPS A;  4AR3 A;  4A3D L;  4E6Y A;  3KYW A;  3M3Y L;  3H99 A;  2JA6 L;  4ME3 A;  4AI1 A;  4JAF A;  1DVB A;  4JAG A;  3IU3 I;  3P2A A;  2JA7 L;  2HR5 A;  4G6B A;  4RXN A;  2R7Z L;  3S15 L;  3HOY L;  1K83 L;  3K35 A;  3VPB E;  3H97 A;  1SMU A;  5M3F L;  5H1S c;  5JVG 1;  3PIO 1;  1Y1V L;  1NXE A;  4Y7N L;  2E2H L;  2DSX A;  4A3F L;  3ZG6 A;  5C44 L;  1WCM L;  3HOV L;  2E2I L;  3H0G L;  2V3B B;  1E8J A;  3J7Z 1;  1FHM A;  4A3E L;  4XGH A;  1QCV A;  2B63 L;  3M4O L;  3PO3 L;  3GTQ L;  3RZ6 A;  2JA5 L;  1H7V A;  2YU9 L;  3WWL A;  2R92 L;  1IRN A;  2PSM C;  5GAG c;  4WFN 1;  4C3J L;  2PVE A;  2A69 D;  8RXN A;  3GTG L;  3PWF A;  5GAH c;  3GTM L;  5MFZ A;  2A68 D;  2NVX L;  4AR6 A;  3A44 A;  1JYB A;  3RYG A;  2JI3 A;  1WJV A;  5IYC L;  1ZRP A;  1F4L A;  5IP7 L;  1BQ8 A;  1ODH A;  7RXN A;  2M4Y A;  4LHL A;  1I3Q L;  1S30 A;  1BE7 A;  2BE5 D;  2L0Z A;  2PYA A;  3B08 B;  2APO B;  3HOX L;  5C3E L;  1SMM A;  3FKI L;  2CKA A;  1DX8 A;  3KYU A;  2XJU A;  3PKJ A;  1VZG A;  1YK5 A;  1PZX A;  4V19 6;  4BBS L;  2M6O A;  2MS3 A;  3S14 L;  1TWC L;  1R0J A;  2HVY C;  4ZN3 B;  2K2D A;  4TVM A;  5M3M L;  4C2M 1;  5MGN A;  4AR5 A;  2VL6 A;  1YUZ A;  5AI3 A;  3HOU L;  2M4V A;  2AUS B;  3S1Q L;  2NYD A;  4AHZ A;  4POG A;  4BBR L;  4A3J L;  2A6H D;  1T9O A;  1RYQ A;  3CQZ L;  3S17 L;  5IP9 L;  4GS7 D;  1FHH A;  2LCQ A;  3MQK B;  1PFU A;  3NFP I;  1S2Z A;  5MFP A;  2ERS A;  3GTL L; 
#chains in the Genus database with same CATH homology
 1QYB A;  1IW7 D;  5GAE c;  1H7V A;  2JI1 A;  1IU5 A;  3WWL A;  3SS2 A;  1IRN A;  2PSM C;  5GAG c;  1B2J A;  2J9U B;  2QL0 A;  3LPE B;  4WFN 1;  2PVE A;  1B13 A;  1YUX A;  4AI0 A;  2XJQ A;  2A69 D;  1IRO A;  8RXN A;  4AHY A;  4JAD A;  5EIN C;  2RDV A;  4AHW A;  5MF6 A;  3PWF A;  1LKM A;  5K2M E;  5GAH c;  1S24 A;  5MFZ A;  1RWD A;  2A68 D;  4AR6 A;  3A44 A;  1JYB A;  2KKD A;  2CKC A;  3RYG A;  1R0F A;  1B71 A;  2JI3 A;  4YWM A;  4K9F A;  1WJV A;  1ZRP A;  1LTL A;  5AN9 H;  1NXG A;  2M6P A;  5EIO C;  2XJV A;  2H12 A;  1LKP A;  1T9P A;  3PZA A;  5IY0 A;  1BQ8 A;  1ODH A;  4AR4 A;  1R0G A;  1VZI A;  4YWL A;  7RXN A;  2M4Y A;  4LHL A;  1LKO A;  1S30 A;  1BE7 A;  1CAA A;  2BE5 D;  2L0Z A;  2PYA A;  1VZH A;  2XJS A;  2XJT A;  1BFY A;  4UY8 1;  2PPT A;  1RDG A;  2ERJ A;  2V0F A;  3B08 B;  4AI3 A;  3MPS A;  1BQ9 A;  2GMG A;  1SMM A;  2KN9 A;  5DM6 1;  3P8B A;  1VCX A;  4AR3 A;  2CKA A;  1BRF A;  4E6Y A;  1DX8 A;  3KYU A;  3KYW A;  4B8C D;  3KYY A;  2C6B A;  2XJU A;  3PKJ A;  1VZG A;  2ZIX A;  1YK5 A;  2PVX A;  1OWC A;  4ME3 A;  4AI1 A;  3QVD A;  4JAF A;  1DVB A;  4JAG A;  4LHN A;  3IU3 I;  3P2A A;  2B5I D;  4V19 6;  1YK4 A;  2A6E D;  2Z3Q B;  2M6O A;  1RDV A;  3LNL A;  1Z92 B;  2HR5 A;  4G6B A;  4RXN A;  1C09 A;  2MS3 A;  1RB9 A;  1R0J A;  3KYV A;  2CR8 A;  4ZN3 B;  4TPU A;  2K2D A;  3PKI A;  4TVM A;  3K35 A;  3VPB E;  4JAE A;  5GAD c;  5MGN A;  1YV1 A;  1SMU A;  4AR5 A;  2VL6 A;  5H1S c;  1YUZ A;  5AI3 A;  2JI2 A;  1T9Q A;  1R0I A;  2M4V A;  4U67 1;  4XXB B;  4AI2 A;  5JVG 1;  3WWN B;  1RYT A;  3PIO 1;  1SMW A;  3RZT A;  3QQC E;  1NXE A;  1IU6 A;  2NYD A;  1NNQ A;  4AHZ A;  4AHX A;  2DSX A;  1OWB A;  5AI2 A;  2AYJ A;  3KYX A;  3ZG6 A;  2XJR A;  2Z3R B;  3B0A B;  1R0H A;  4POG A;  2A6H D;  1T9O A;  3MSU A;  1RYQ A;  5RXN A;  1CAD A;  2XJP A;  3PIP 1;  5DM7 1;  5MLC 3;  2V3B B;  4GS7 D;  1FHH A;  2LCQ A;  4POF A;  3J7Z 1;  2C6A A;  1FHM A;  5JVH 1;  1E8J A;  3J7Y 1;  2V0E A;  2O5J D;  1B2O A;  3NFP I;  1QCV A;  4XGH A;  4ZN1 B;  1S2Z A;  6RXN A;  5MFP A;  2ERS A;  3RZ6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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