5C3EL

Crystal structure of a transcribing rna polymerase ii complex reveals a complete transcription bubble
Total Genus 2
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
2
sequence length
43
structure length
43
Chain Sequence
KYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
pubmed doi rcsb
molecule tags Transferase/dna/rna
source organism Saccharomyces cerevisiae (strain atcc 204508 / s288c)
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 2
structure length 43
sequence length 43
ec nomenclature
pdb deposition date 2015-06-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 5c3eL00
1Y1VL 3K7AL 2E2IL 1R9TL 3RZOL 3GTLL 4BY7L 2Y0SP 2B63L 4A3CL 4A3LL 4C3JL 1TWHL 1TWGL 4A3KL 4AYBP 3HOXL 2JA8L 3S2HL 4A3BL 1I50L 5M5XL 2NVYL 3HOYL 5M3ML 2WAQP 2JA7L 3HOZL 4C3IL 4Y7NL 3I4ML 3GTOL 4A3IL 3PO2L 1K83L 3M3YL 3GTGL 3GTML 5IP9L 3I4NL 3GTKL 2PMZP 3S1ML 5M5WL 3HOWL 5IYBL 3HKZP 5IYDL 1TWAL 3GTJL 1I6HL 5C44L 4A3GL 2R7ZL 3M4OL 2E2JL 2WB1P 3S16L 4C3HL 4X6AL 1WCML 5FJ8L 4A3FL 1SFOL 3HOVL 2YU9L 2VUML 5C4XL 3S1RL 5FLML 3GTPL 1I3QL 5M3FL 3S15L 1TWCL 4A3EL 3S2DL 4Y52L 2R93L 3S14L 5C3EL 3S1NL 4C2M1 3FKIL 1Y1WL 4QIWP 3PO3L 4BY1L 4BBRL 2E2HL 2JA5L 3H3VM 4A93L 4BXXL 2JA6L 3GTQL 4A3JL 2NVQL 5IP7L 3S1QL 5C4JL 3RZDL 3H0GL 4BBSL 2NVXL 3CQZL 5M5YL 2NVTL 4A3DL 1TWFL 2R92L 4A3ML 5IYCL 3S17L 3HOUL
chains in the Genus database with same CATH superfamily
4ZN3B 1Y1VL 2E2IL 3GTLL 3PKJA 5AI2A 3H97A 1C09A 3P2AA 2MS3A 1OWBA 4A3CL 4A3LL 4AR6A 3HOXL 5MFZA 3S2HL 2XJPA 4V196 1OWCA 3MSUA 4WFN1 2WAQP 2JA7L 2Z3QB 3GTOL 4A3IL 4POGA 5IP9L 3S1ML 1ODHA 3HOWL 2PSMC 1BE7A 6RXNA 4POFA 2M6PA 1I6HL 2O5JD 2R7ZL 2PVXA 1VZHA 5RXNA 1R0JA 3WWLA 1R0FA 4AI2A 3KYVA 1PFWA 3HOVL 3HJWB 4JADA 5C4XL 4AHZA 3HJYB 1FHMA 3S15L 4AR4A 3LWRB 1YK4A 3S1NL 4C2M1 3LWVB 1QYBA 3MPSA 3WWNB 4U671 4BXXL 1NXEA 1IW7D 4A3JL 3QQCE 3LPEB 5IP7L 2EY4E 2JI1A 1SMWA 1ZRPA 1S2ZA 4A3ML 3KYYA 1Z92B 1R0IA 1QQTA 4G6BA 2AYJA 1R9TL 4GS7D 4YWMA 5MFPA 2XJTA 1PFUA 4C3JL 1TWGL 1S24A 4AYBP 5GAEc 5JVH1 2CKCA 2JA8L 4YWLA 3MQKB 1I50L 4A3BL 1IRNA 5M5XL 4Y7NL 3J7Z1 1K83L 3M3YL 3GTML 4TPUA 3JR7A 4K9FA 3PL5A 2XJRA 5IYDL 2JI2A 1PFVA 1B13A 2K2DA 5AN9H 3KYWA 5IY0A 4RXNA 1PZXA 1VZIA 1RB9A 1F4LA 3FDJA 1YK5A 3LNLA 1WCML 5FJ8L 4A3FL 3ZG6A 1LKPA 7RXNA 1YV1A 3S1RL 2KKDA 3GTPL 2M4VA 2J9UB 3S2DL 2R93L 5GAGc 5C3EL 1E8JA 1RYTA 1Y1WL 4QIWP 2PPTA 4BBRL 4BY1L 2ERJA 3H3VM 2ZIXA 4JAFA 3H9CA 1SMMA 1SMUA 2JA6L 1CAAA 4ZN1B 1YUXA 1T9QA 4UY81 2NVTL 2R92L 2C6BA 2V3BB 5MF6A 1BFYA 3HOUL 2PVEA 2ERSA 4LHLA 3K7AL 3RZOL 5GAHc 2B63L 1BQ9A 4XGHA 5JVG1 3QVDA 2XJQA 2A68D 1IU6A 2JI3A 2L0ZA 1BRFA 3PIO1 2RFKB 2NVYL 1WJVA 3H99A 3B0AB 2A6ED 3I4ML 3GTGL 4LHNA 8RXNA 2CKAA 3I4NL 3GTKL 2PMZP 4AR3A 5M5WL 3LWQB 2C6AA 1TWAL 2PYAA 1RYQA 2GMGA 5C44L 2E2JL 5GADc 2RDVA 3RYGA 2QL0A 2V0FA 3S16L 4X6AL 2VL6A 1B2OA 1B2JA 5AI3A 2YU9L 2VUML 4ME3A 2DSXA 3KYXA 4A3EL 2NYDA 5MLC3 1VCXA 3FKIL 3PO3L 1PFYA 2E2HL 2JA5L 1RDGA 4A93L 4XXBB 2V0EA 4AHXA 1VZGA 4AHWA 5EIOC 3PWFA 3LWOB 3S1QL 3H9BA 3RZDL 3H0GL 2M4YA 1IU5A 2NVXL 1BQ8A 4AHYA 5M5YL 1JYBA 1TWFL 3VPBE 2AUSB 2XJUA 4BY7L 2APOB 1IROA 2Y0SP 1TWHL 1T9OA 4A3KL 2AQCA 2A69D 2M6OA 3PKIA 1B71A 4JAGA 3P8BA 5DM71 3HOYL 5M3ML 3HOZL 4C3IL 3A44A 5DM61 4AI3A 3PO2L 1R0HA 3PZAA 3RZTA 2Z3RB 4AI1A 4E6YA 5H1Sc 2A6HD 1YUZA 1LKMA 3NFPI 1RWDA 5IYBL 4AR5A 3HKZP 3PIP1 2CR8A 1DX8A 3GTJL 1R0GA 4A3GL 1P7PA 3M4OL 1LKOA 5K2ME 2WB1P 1LTLA 2HR5A 2BE5D 4C3HL 1S30A 1SFOL 4AI0A 2B5ID 1NNQA 3K35A 5FLML 1I3QL 5M3FL 1TWCL 4Y52L 1QCVA 3S14L 1NXGA 2KN9A 3KYUA 4TVMA 3LWPB 3J7Y1 1CADA 3IU3I 4B8CD 2XJSA 3GTQL 2NVQL 2XJVA 3RZ6A 2H12A 5C4JL 4BBSL 5MGNA 4JAEA 5EINC 1RDVA 3CQZL 3SS2A 2LCQA 1DVBA 4A3DL 1FHHA 2HVYC 5IYCL 1H7VA 3S17L 1T9PA 3HAXC 3B08B
chains in the Genus database with same CATH topology
1Y1VL 3K7AL 2E2IL 1R9TL 3RZOL 3GTLL 4BY7L 2Y0SP 2B63L 4A3CL 4A3LL 4C3JL 1TWHL 1TWGL 4A3KL 4AYBP 3HOXL 2JA8L 3S2HL 4A3BL 1I50L 5M5XL 2NVYL 3HOYL 5M3ML 2WAQP 2JA7L 3HOZL 4C3IL 4Y7NL 3I4ML 3GTOL 4A3IL 3PO2L 1K83L 3M3YL 3GTGL 3GTML 5IP9L 3I4NL 3GTKL 2PMZP 3S1ML 5M5WL 3HOWL 5IYBL 3HKZP 5IYDL 1TWAL 3GTJL 1I6HL 5C44L 4A3GL 2R7ZL 3M4OL 2E2JL 2WB1P 3S16L 4C3HL 4X6AL 1WCML 5FJ8L 4A3FL 1SFOL 3HOVL 2YU9L 2VUML 5C4XL 3S1RL 5FLML 3GTPL 1I3QL 5M3FL 3S15L 1TWCL 4A3EL 3S2DL 4Y52L 2R93L 3S14L 5C3EL 3S1NL 4C2M1 3FKIL 1Y1WL 4QIWP 3PO3L 4BY1L 4BBRL 2E2HL 2JA5L 3H3VM 4A93L 4BXXL 2JA6L 3GTQL 4A3JL 2NVQL 5IP7L 3S1QL 5C4JL 3RZDL 3H0GL 4BBSL 2NVXL 3CQZL 5M5YL 2NVTL 4A3DL 1TWFL 2R92L 4A3ML 5IYCL 3S17L 3HOUL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Y1V L;  3K7A L;  2E2I L;  1R9T L;  3RZO L;  3GTL L;  4BY7 L;  2Y0S P;  2B63 L;  4A3C L;  4A3L L;  4C3J L;  1TWH L;  1TWG L;  4A3K L;  4AYB P;  3HOX L;  2JA8 L;  3S2H L;  4A3B L;  1I50 L;  5M5X L;  2NVY L;  3HOY L;  5M3M L;  2WAQ P;  2JA7 L;  3HOZ L;  4C3I L;  4Y7N L;  3I4M L;  3GTO L;  4A3I L;  3PO2 L;  1K83 L;  3M3Y L;  3GTG L;  3GTM L;  5IP9 L;  3I4N L;  3GTK L;  2PMZ P;  3S1M L;  5M5W L;  3HOW L;  5IYB L;  3HKZ P;  5IYD L;  1TWA L;  3GTJ L;  1I6H L;  5C44 L;  4A3G L;  2R7Z L;  3M4O L;  2E2J L;  2WB1 P;  3S16 L;  4C3H L;  4X6A L;  1WCM L;  5FJ8 L;  4A3F L;  1SFO L;  3HOV L;  2YU9 L;  2VUM L;  5C4X L;  3S1R L;  5FLM L;  3GTP L;  1I3Q L;  5M3F L;  3S15 L;  1TWC L;  4A3E L;  3S2D L;  4Y52 L;  2R93 L;  3S14 L;  5C3E L;  3S1N L;  4C2M 1;  3FKI L;  1Y1W L;  4QIW P;  3PO3 L;  4BY1 L;  4BBR L;  2E2H L;  2JA5 L;  3H3V M;  4A93 L;  4BXX L;  2JA6 L;  3GTQ L;  4A3J L;  2NVQ L;  5IP7 L;  3S1Q L;  5C4J L;  3RZD L;  3H0G L;  4BBS L;  2NVX L;  3CQZ L;  5M5Y L;  2NVT L;  4A3D L;  1TWF L;  2R92 L;  4A3M L;  5IYC L;  3S17 L;  3HOU L; 
#chains in the Genus database with same CATH topology
 4ZN3 B;  1Y1V L;  2E2I L;  3GTL L;  3PKJ A;  5AI2 A;  3H97 A;  1C09 A;  3P2A A;  2MS3 A;  1OWB A;  4A3C L;  4A3L L;  4AR6 A;  3HOX L;  5MFZ A;  3S2H L;  2XJP A;  4V19 6;  1OWC A;  3MSU A;  4WFN 1;  2WAQ P;  2JA7 L;  2Z3Q B;  3GTO L;  4A3I L;  4POG A;  5IP9 L;  3S1M L;  1ODH A;  3HOW L;  2PSM C;  1BE7 A;  6RXN A;  4POF A;  2M6P A;  1I6H L;  2O5J D;  2R7Z L;  2PVX A;  1VZH A;  5RXN A;  1R0J A;  3WWL A;  1R0F A;  4AI2 A;  3KYV A;  1PFW A;  3HOV L;  3HJW B;  4JAD A;  5C4X L;  4AHZ A;  3HJY B;  1FHM A;  3S15 L;  4AR4 A;  3LWR B;  1YK4 A;  3S1N L;  4C2M 1;  3LWV B;  1QYB A;  3MPS A;  3WWN B;  4U67 1;  4BXX L;  1NXE A;  1IW7 D;  4A3J L;  3QQC E;  3LPE B;  5IP7 L;  2EY4 E;  2JI1 A;  1SMW A;  1ZRP A;  1S2Z A;  4A3M L;  3KYY A;  1Z92 B;  1R0I A;  1QQT A;  4G6B A;  2AYJ A;  1R9T L;  4GS7 D;  4YWM A;  5MFP A;  2XJT A;  1PFU A;  4C3J L;  1TWG L;  1S24 A;  4AYB P;  5GAE c;  5JVH 1;  2CKC A;  2JA8 L;  4YWL A;  3MQK B;  1I50 L;  4A3B L;  1IRN A;  5M5X L;  4Y7N L;  3J7Z 1;  1K83 L;  3M3Y L;  3GTM L;  4TPU A;  3JR7 A;  4K9F A;  3PL5 A;  2XJR A;  5IYD L;  2JI2 A;  1PFV A;  1B13 A;  2K2D A;  5AN9 H;  3KYW A;  5IY0 A;  4RXN A;  1PZX A;  1VZI A;  1RB9 A;  1F4L A;  3FDJ A;  1YK5 A;  3LNL A;  1WCM L;  5FJ8 L;  4A3F L;  3ZG6 A;  1LKP A;  7RXN A;  1YV1 A;  3S1R L;  2KKD A;  3GTP L;  2M4V A;  2J9U B;  3S2D L;  2R93 L;  5GAG c;  5C3E L;  1E8J A;  1RYT A;  1Y1W L;  4QIW P;  2PPT A;  4BBR L;  4BY1 L;  2ERJ A;  3H3V M;  2ZIX A;  4JAF A;  3H9C A;  1SMM A;  1SMU A;  2JA6 L;  1CAA A;  4ZN1 B;  1YUX A;  1T9Q A;  4UY8 1;  2NVT L;  2R92 L;  2C6B A;  2V3B B;  5MF6 A;  1BFY A;  3HOU L;  2PVE A;  2ERS A;  4LHL A;  3K7A L;  3RZO L;  5GAH c;  2B63 L;  1BQ9 A;  4XGH A;  5JVG 1;  3QVD A;  2XJQ A;  2A68 D;  1IU6 A;  2JI3 A;  2L0Z A;  1BRF A;  3PIO 1;  2RFK B;  2NVY L;  1WJV A;  3H99 A;  3B0A B;  2A6E D;  3I4M L;  3GTG L;  4LHN A;  8RXN A;  2CKA A;  3I4N L;  3GTK L;  2PMZ P;  4AR3 A;  5M5W L;  3LWQ B;  2C6A A;  1TWA L;  2PYA A;  1RYQ A;  2GMG A;  5C44 L;  2E2J L;  5GAD c;  2RDV A;  3RYG A;  2QL0 A;  2V0F A;  3S16 L;  4X6A L;  2VL6 A;  1B2O A;  1B2J A;  5AI3 A;  2YU9 L;  2VUM L;  4ME3 A;  2DSX A;  3KYX A;  4A3E L;  2NYD A;  5MLC 3;  1VCX A;  3FKI L;  3PO3 L;  1PFY A;  2E2H L;  2JA5 L;  1RDG A;  4A93 L;  4XXB B;  2V0E A;  4AHX A;  1VZG A;  4AHW A;  5EIO C;  3PWF A;  3LWO B;  3S1Q L;  3H9B A;  3RZD L;  3H0G L;  2M4Y A;  1IU5 A;  2NVX L;  1BQ8 A;  4AHY A;  5M5Y L;  1JYB A;  1TWF L;  3VPB E;  2AUS B;  2XJU A;  4BY7 L;  2APO B;  1IRO A;  2Y0S P;  1TWH L;  1T9O A;  4A3K L;  2AQC A;  2A69 D;  2M6O A;  3PKI A;  1B71 A;  4JAG A;  3P8B A;  5DM7 1;  3HOY L;  5M3M L;  3HOZ L;  4C3I L;  3A44 A;  5DM6 1;  4AI3 A;  3PO2 L;  1R0H A;  3PZA A;  3RZT A;  2Z3R B;  4AI1 A;  4E6Y A;  5H1S c;  2A6H D;  1YUZ A;  1LKM A;  3NFP I;  1RWD A;  5IYB L;  4AR5 A;  3HKZ P;  3PIP 1;  2CR8 A;  1DX8 A;  3GTJ L;  1R0G A;  4A3G L;  1P7P A;  3M4O L;  1LKO A;  5K2M E;  2WB1 P;  1LTL A;  2HR5 A;  2BE5 D;  4C3H L;  1S30 A;  1SFO L;  4AI0 A;  2B5I D;  1NNQ A;  3K35 A;  5FLM L;  1I3Q L;  5M3F L;  1TWC L;  4Y52 L;  1QCV A;  3S14 L;  1NXG A;  2KN9 A;  3KYU A;  4TVM A;  3LWP B;  3J7Y 1;  1CAD A;  3IU3 I;  4B8C D;  2XJS A;  3GTQ L;  2NVQ L;  2XJV A;  3RZ6 A;  2H12 A;  5C4J L;  4BBS L;  5MGN A;  4JAE A;  5EIN C;  1RDV A;  3CQZ L;  3SS2 A;  2LCQ A;  1DVB A;  4A3D L;  1FHH A;  2HVY C;  5IYC L;  1H7V A;  3S17 L;  1T9P A;  3HAX C;  3B08 B; 
#chains in the Genus database with same CATH homology
 1Y1V L;  3K7A L;  2E2I L;  1R9T L;  3RZO L;  3GTL L;  4BY7 L;  2Y0S P;  2B63 L;  4A3C L;  4A3L L;  4C3J L;  1TWH L;  1TWG L;  4A3K L;  4AYB P;  3HOX L;  2JA8 L;  3S2H L;  4A3B L;  1I50 L;  5M5X L;  2NVY L;  3HOY L;  5M3M L;  2WAQ P;  2JA7 L;  3HOZ L;  4C3I L;  4Y7N L;  3I4M L;  3GTO L;  4A3I L;  3PO2 L;  1K83 L;  3M3Y L;  3GTG L;  3GTM L;  5IP9 L;  3I4N L;  3GTK L;  2PMZ P;  3S1M L;  5M5W L;  3HOW L;  5IYB L;  3HKZ P;  5IYD L;  1TWA L;  3GTJ L;  1I6H L;  5C44 L;  4A3G L;  2R7Z L;  3M4O L;  2E2J L;  2WB1 P;  3S16 L;  4C3H L;  4X6A L;  1WCM L;  5FJ8 L;  4A3F L;  1SFO L;  3HOV L;  2YU9 L;  2VUM L;  5C4X L;  3S1R L;  5FLM L;  3GTP L;  1I3Q L;  5M3F L;  3S15 L;  1TWC L;  4A3E L;  3S2D L;  4Y52 L;  2R93 L;  3S14 L;  5C3E L;  3S1N L;  4C2M 1;  3FKI L;  1Y1W L;  4QIW P;  3PO3 L;  4BY1 L;  4BBR L;  2E2H L;  2JA5 L;  3H3V M;  4A93 L;  4BXX L;  2JA6 L;  3GTQ L;  4A3J L;  2NVQ L;  5IP7 L;  3S1Q L;  5C4J L;  3RZD L;  3H0G L;  4BBS L;  2NVX L;  3CQZ L;  5M5Y L;  2NVT L;  4A3D L;  1TWF L;  2R92 L;  4A3M L;  5IYC L;  3S17 L;  3HOU L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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