5C44L

Crystal structure of a transcribing rna polymerase ii complex reveals a complete transcription bubble
Total Genus 2
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
2
sequence length
44
structure length
44
Chain Sequence
LKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
pubmed doi rcsb
molecule tags Transferase/dna/rna
source organism Saccharomyces cerevisiae (strain atcc 204508 / s288c)
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 2
structure length 44
sequence length 44
ec nomenclature
pdb deposition date 2015-06-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 5c44L00
3PO2L 3RZOL 1I6HL 2JA7L 2VUML 4C3HL 5FLML 3GTQL 5C4JL 4A3BL 1Y1WL 2NVXL 4A3JL 3HKZP 2E2JL 3I4NL 1TWAL 3S2DL 4A3KL 1SFOL 3I4ML 2WAQP 2WB1P 2Y0SP 5C3EL 4A3FL 5M3FL 1TWFL 2E2IL 3GTPL 4BBSL 3CQZL 5FJ8L 3HOUL 2NVTL 2R7ZL 3H0GL 3GTLL 1I3QL 3H3VM 2E2HL 4C3JL 3S1RL 2JA5L 4C2M1 3HOWL 4BY1L 5IP7L 3S14L 2NVQL 4A3GL 4BBRL 3GTGL 4A93L 4A3EL 3S17L 4A3CL 3FKIL 5M5YL 4C3IL 2JA8L 3S1QL 3K7AL 3GTJL 3HOXL 4BY7L 4BXXL 5IYDL 4A3LL 4Y7NL 4AYBP 2B63L 2PMZP 1Y1VL 2JA6L 5M3ML 3HOYL 3M3YL 3GTOL 4A3ML 3GTKL 1I50L 3HOZL 4A3IL 1TWHL 2NVYL 3S16L 3S1NL 1WCML 1TWGL 3M4OL 5IYBL 4QIWP 3PO3L 4X6AL 5C44L 3RZDL 4Y52L 5IP9L 2YU9L 1TWCL 5M5XL 5IYCL 3GTML 3S1ML 4A3DL 1K83L 5C4XL 3HOVL 3S15L 5M5WL 1R9TL 3S2HL 2R93L 2R92L
chains in the Genus database with same CATH superfamily
3KYYA 1FHMA 3HJWB 3RZTA 3MSUA 3RYGA 2CKAA 2EY4E 4UY81 2GMGA 3LWVB 1B2OA 1YUZA 4GS7D 4AHZA 2NVXL 3K35A 5K2ME 5EIOC 4YWLA 5GAGc 5MFPA 2DSXA 2WB1P 2V0EA 4AR5A 1SMMA 4LHNA 2E2IL 3J7Z1 1S30A 3HOUL 2R7ZL 4AHYA 1S24A 2PVEA 3B08B 3H3VM 1R0FA 2PVXA 4C3JL 2PYAA 3HOWL 5IP7L 3S14L 2NVQL 4WFN1 5AN9H 3S17L 3RZ6A 2KKDA 1S2ZA 5M5YL 2JA8L 3K7AL 4BXXL 4Y7NL 1LKOA 3PWFA 1R0HA 3KYVA 2AQCA 3HJYB 2A69D 1Z92B 3HAXC 1NNQA 2JA6L 1BRFA 5AI2A 1YUXA 3WWNB 1RDGA 4A3ML 1RDVA 5GADc 3LNLA 1QYBA 2HVYC 1VZIA 3HOZL 2LCQA 1TWHL 1RYQA 5MLC3 1C09A 3LWOB 7RXNA 5IYBL 3PO3L 4X6AL 2PSMC 1LKPA 4Y52L 5M5XL 1K83L 5C4XL 3IU3I 1YK4A 2Z3QB 1NXEA 5JVH1 1T9PA 5MF6A 1I6HL 2XJSA 3PZAA 5FLML 3GTQL 5C4JL 4A3BL 1Y1WL 3I4NL 1TWAL 3S2DL 3I4ML 2WAQP 5M3FL 1TWFL 2J9UB 3CQZL 5FJ8L 2RDVA 4XGHA 4RXNA 3GTLL 4AHXA 4YWMA 2E2HL 1F4LA 2VL6A 2JI1A 2A6HD 2JA5L 2KN9A 2A68D 4BBRL 4ZN1B 1ZRPA 2ZIXA 4A3EL 3FKIL 2H12A 4TVMA 4C3IL 3HOXL 3KYUA 1BFYA 1Y1VL 5M3ML 4AI2A 2A6ED 1IW7D 3M3YL 3GTOL 1E8JA 3PKJA 1I50L 3J7Y1 1LKMA 1RYTA 3LWPB 3LWRB 1B71A 3SS2A 4AR4A 4POFA 1R0JA 2XJQA 1TWGL 4TPUA 1RB9A 3M4OL 3QQCE 2PPTA 3MPSA 3H9BA 3RZDL 4JADA 1T9OA 1JYBA 4K9FA 5DM61 4AI3A 2XJPA 5IP9L 2YU9L 1TWCL 5RXNA 5IYCL 3S1ML 4A3DL 2L0ZA 1RWDA 5IY0A 3MQKB 2JI2A 2M6PA 3PL5A 2JA7L 2VUML 3LPEB 4C3HL 2CKCA 3H97A 1T9QA 4AI0A 2XJTA 3PIO1 3ZG6A 3HKZP 2B5ID 2MS3A 1DX8A 2RFKB 2Y0SP 8RXNA 4BBSL 3P8BA 1SMUA 3A44A 1YK5A 2NVTL 3JR7A 6RXNA 3PIP1 1PFYA 3H0GL 1QQTA 3PKIA 1I3QL 2M4VA 4JAEA 3NFPI 5MFZA 3S1RL 2M4YA 1FHHA 4A3GL 2NYDA 4A93L 2V0FA 4A3CL 2Z3RB 3S1QL 1VZHA 4E6YA 4AYBP 2B63L 1OWCA 2BE5D 2AUSB 3H9CA 4U671 2C6AA 1IROA 3GTKL 1CAAA 3LWQB 1ODHA 1R0IA 3WWLA 3S1NL 1WCML 4G6BA 1R0GA 5JVG1 4QIWP 1OWBA 4LHLA 1VZGA 4AI1A 2C6BA 3GTML 1DVBA 2M6OA 2O5JD 1PFVA 2R92L 3PO2L 3RZOL 3B0AB 1IU5A 3KYWA 4V196 1SMWA 4A3JL 2E2JL 1BQ8A 3FDJA 4AHWA 4A3KL 1SFOL 5C3EL 1PFUA 3VPBE 2V3BB 4A3FL 3GTPL 1CADA 5H1Sc 5MGNA 1BQ9A 2XJRA 2ERSA 3QVDA 2XJUA 2K2DA 4JAFA 4B8CD 4C2M1 4BY1L 2HR5A 1B13A 1IU6A 1P7PA 3GTGL 1B2JA 3P2AA 2JI3A 5AI3A 5DM71 1PZXA 3GTJL 4BY7L 5IYDL 4A3LL 1NXGA 2CR8A 2PMZP 3H99A 4JAGA 1WJVA 4XXBB 4ZN3B 4AR6A 3HOYL 2QL0A 1H7VA 1LTLA 1PFWA 1VCXA 2XJVA 2AYJA 5GAHc 4A3IL 2APOB 4ME3A 2NVYL 3S16L 3KYXA 4POGA 5C44L 4AR3A 1YV1A 1BE7A 1IRNA 5GAEc 5EINC 3HOVL 2ERJA 1QCVA 3S15L 5M5WL 1R9TL 3S2HL 2R93L
chains in the Genus database with same CATH topology
3PO2L 3RZOL 1I6HL 2JA7L 2VUML 4C3HL 5FLML 3GTQL 5C4JL 4A3BL 1Y1WL 2NVXL 4A3JL 3HKZP 2E2JL 3I4NL 1TWAL 3S2DL 4A3KL 1SFOL 3I4ML 2WAQP 2WB1P 2Y0SP 5C3EL 4A3FL 5M3FL 1TWFL 2E2IL 3GTPL 4BBSL 3CQZL 5FJ8L 3HOUL 2NVTL 2R7ZL 3H0GL 3GTLL 1I3QL 3H3VM 2E2HL 4C3JL 3S1RL 2JA5L 4C2M1 3HOWL 4BY1L 5IP7L 3S14L 2NVQL 4A3GL 4BBRL 3GTGL 4A93L 4A3EL 3S17L 4A3CL 3FKIL 5M5YL 4C3IL 2JA8L 3S1QL 3K7AL 3GTJL 3HOXL 4BY7L 4BXXL 5IYDL 4A3LL 4Y7NL 4AYBP 2B63L 2PMZP 1Y1VL 2JA6L 5M3ML 3HOYL 3M3YL 3GTOL 4A3ML 3GTKL 1I50L 3HOZL 4A3IL 1TWHL 2NVYL 3S16L 3S1NL 1WCML 1TWGL 3M4OL 5IYBL 4QIWP 3PO3L 4X6AL 5C44L 3RZDL 4Y52L 5IP9L 2YU9L 1TWCL 5M5XL 5IYCL 3GTML 3S1ML 4A3DL 1K83L 5C4XL 3HOVL 3S15L 5M5WL 1R9TL 3S2HL 2R93L 2R92L
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PO2 L;  3RZO L;  1I6H L;  2JA7 L;  2VUM L;  4C3H L;  5FLM L;  3GTQ L;  5C4J L;  4A3B L;  1Y1W L;  2NVX L;  4A3J L;  3HKZ P;  2E2J L;  3I4N L;  1TWA L;  3S2D L;  4A3K L;  1SFO L;  3I4M L;  2WAQ P;  2WB1 P;  2Y0S P;  5C3E L;  4A3F L;  5M3F L;  1TWF L;  2E2I L;  3GTP L;  4BBS L;  3CQZ L;  5FJ8 L;  3HOU L;  2NVT L;  2R7Z L;  3H0G L;  3GTL L;  1I3Q L;  3H3V M;  2E2H L;  4C3J L;  3S1R L;  2JA5 L;  4C2M 1;  3HOW L;  4BY1 L;  5IP7 L;  3S14 L;  2NVQ L;  4A3G L;  4BBR L;  3GTG L;  4A93 L;  4A3E L;  3S17 L;  4A3C L;  3FKI L;  5M5Y L;  4C3I L;  2JA8 L;  3S1Q L;  3K7A L;  3GTJ L;  3HOX L;  4BY7 L;  4BXX L;  5IYD L;  4A3L L;  4Y7N L;  4AYB P;  2B63 L;  2PMZ P;  1Y1V L;  2JA6 L;  5M3M L;  3HOY L;  3M3Y L;  3GTO L;  4A3M L;  3GTK L;  1I50 L;  3HOZ L;  4A3I L;  1TWH L;  2NVY L;  3S16 L;  3S1N L;  1WCM L;  1TWG L;  3M4O L;  5IYB L;  4QIW P;  3PO3 L;  4X6A L;  5C44 L;  3RZD L;  4Y52 L;  5IP9 L;  2YU9 L;  1TWC L;  5M5X L;  5IYC L;  3GTM L;  3S1M L;  4A3D L;  1K83 L;  5C4X L;  3HOV L;  3S15 L;  5M5W L;  1R9T L;  3S2H L;  2R93 L;  2R92 L; 
#chains in the Genus database with same CATH topology
 3KYY A;  1FHM A;  3HJW B;  3RZT A;  3MSU A;  3RYG A;  2CKA A;  2EY4 E;  4UY8 1;  2GMG A;  3LWV B;  1B2O A;  1YUZ A;  4GS7 D;  4AHZ A;  2NVX L;  3K35 A;  5K2M E;  5EIO C;  4YWL A;  5GAG c;  5MFP A;  2DSX A;  2WB1 P;  2V0E A;  4AR5 A;  1SMM A;  4LHN A;  2E2I L;  3J7Z 1;  1S30 A;  3HOU L;  2R7Z L;  4AHY A;  1S24 A;  2PVE A;  3B08 B;  3H3V M;  1R0F A;  2PVX A;  4C3J L;  2PYA A;  3HOW L;  5IP7 L;  3S14 L;  2NVQ L;  4WFN 1;  5AN9 H;  3S17 L;  3RZ6 A;  2KKD A;  1S2Z A;  5M5Y L;  2JA8 L;  3K7A L;  4BXX L;  4Y7N L;  1LKO A;  3PWF A;  1R0H A;  3KYV A;  2AQC A;  3HJY B;  2A69 D;  1Z92 B;  3HAX C;  1NNQ A;  2JA6 L;  1BRF A;  5AI2 A;  1YUX A;  3WWN B;  1RDG A;  4A3M L;  1RDV A;  5GAD c;  3LNL A;  1QYB A;  2HVY C;  1VZI A;  3HOZ L;  2LCQ A;  1TWH L;  1RYQ A;  5MLC 3;  1C09 A;  3LWO B;  7RXN A;  5IYB L;  3PO3 L;  4X6A L;  2PSM C;  1LKP A;  4Y52 L;  5M5X L;  1K83 L;  5C4X L;  3IU3 I;  1YK4 A;  2Z3Q B;  1NXE A;  5JVH 1;  1T9P A;  5MF6 A;  1I6H L;  2XJS A;  3PZA A;  5FLM L;  3GTQ L;  5C4J L;  4A3B L;  1Y1W L;  3I4N L;  1TWA L;  3S2D L;  3I4M L;  2WAQ P;  5M3F L;  1TWF L;  2J9U B;  3CQZ L;  5FJ8 L;  2RDV A;  4XGH A;  4RXN A;  3GTL L;  4AHX A;  4YWM A;  2E2H L;  1F4L A;  2VL6 A;  2JI1 A;  2A6H D;  2JA5 L;  2KN9 A;  2A68 D;  4BBR L;  4ZN1 B;  1ZRP A;  2ZIX A;  4A3E L;  3FKI L;  2H12 A;  4TVM A;  4C3I L;  3HOX L;  3KYU A;  1BFY A;  1Y1V L;  5M3M L;  4AI2 A;  2A6E D;  1IW7 D;  3M3Y L;  3GTO L;  1E8J A;  3PKJ A;  1I50 L;  3J7Y 1;  1LKM A;  1RYT A;  3LWP B;  3LWR B;  1B71 A;  3SS2 A;  4AR4 A;  4POF A;  1R0J A;  2XJQ A;  1TWG L;  4TPU A;  1RB9 A;  3M4O L;  3QQC E;  2PPT A;  3MPS A;  3H9B A;  3RZD L;  4JAD A;  1T9O A;  1JYB A;  4K9F A;  5DM6 1;  4AI3 A;  2XJP A;  5IP9 L;  2YU9 L;  1TWC L;  5RXN A;  5IYC L;  3S1M L;  4A3D L;  2L0Z A;  1RWD A;  5IY0 A;  3MQK B;  2JI2 A;  2M6P A;  3PL5 A;  2JA7 L;  2VUM L;  3LPE B;  4C3H L;  2CKC A;  3H97 A;  1T9Q A;  4AI0 A;  2XJT A;  3PIO 1;  3ZG6 A;  3HKZ P;  2B5I D;  2MS3 A;  1DX8 A;  2RFK B;  2Y0S P;  8RXN A;  4BBS L;  3P8B A;  1SMU A;  3A44 A;  1YK5 A;  2NVT L;  3JR7 A;  6RXN A;  3PIP 1;  1PFY A;  3H0G L;  1QQT A;  3PKI A;  1I3Q L;  2M4V A;  4JAE A;  3NFP I;  5MFZ A;  3S1R L;  2M4Y A;  1FHH A;  4A3G L;  2NYD A;  4A93 L;  2V0F A;  4A3C L;  2Z3R B;  3S1Q L;  1VZH A;  4E6Y A;  4AYB P;  2B63 L;  1OWC A;  2BE5 D;  2AUS B;  3H9C A;  4U67 1;  2C6A A;  1IRO A;  3GTK L;  1CAA A;  3LWQ B;  1ODH A;  1R0I A;  3WWL A;  3S1N L;  1WCM L;  4G6B A;  1R0G A;  5JVG 1;  4QIW P;  1OWB A;  4LHL A;  1VZG A;  4AI1 A;  2C6B A;  3GTM L;  1DVB A;  2M6O A;  2O5J D;  1PFV A;  2R92 L;  3PO2 L;  3RZO L;  3B0A B;  1IU5 A;  3KYW A;  4V19 6;  1SMW A;  4A3J L;  2E2J L;  1BQ8 A;  3FDJ A;  4AHW A;  4A3K L;  1SFO L;  5C3E L;  1PFU A;  3VPB E;  2V3B B;  4A3F L;  3GTP L;  1CAD A;  5H1S c;  5MGN A;  1BQ9 A;  2XJR A;  2ERS A;  3QVD A;  2XJU A;  2K2D A;  4JAF A;  4B8C D;  4C2M 1;  4BY1 L;  2HR5 A;  1B13 A;  1IU6 A;  1P7P A;  3GTG L;  1B2J A;  3P2A A;  2JI3 A;  5AI3 A;  5DM7 1;  1PZX A;  3GTJ L;  4BY7 L;  5IYD L;  4A3L L;  1NXG A;  2CR8 A;  2PMZ P;  3H99 A;  4JAG A;  1WJV A;  4XXB B;  4ZN3 B;  4AR6 A;  3HOY L;  2QL0 A;  1H7V A;  1LTL A;  1PFW A;  1VCX A;  2XJV A;  2AYJ A;  5GAH c;  4A3I L;  2APO B;  4ME3 A;  2NVY L;  3S16 L;  3KYX A;  4POG A;  5C44 L;  4AR3 A;  1YV1 A;  1BE7 A;  1IRN A;  5GAE c;  5EIN C;  3HOV L;  2ERJ A;  1QCV A;  3S15 L;  5M5W L;  1R9T L;  3S2H L;  2R93 L; 
#chains in the Genus database with same CATH homology
 3PO2 L;  3RZO L;  1I6H L;  2JA7 L;  2VUM L;  4C3H L;  5FLM L;  3GTQ L;  5C4J L;  4A3B L;  1Y1W L;  2NVX L;  4A3J L;  3HKZ P;  2E2J L;  3I4N L;  1TWA L;  3S2D L;  4A3K L;  1SFO L;  3I4M L;  2WAQ P;  2WB1 P;  2Y0S P;  5C3E L;  4A3F L;  5M3F L;  1TWF L;  2E2I L;  3GTP L;  4BBS L;  3CQZ L;  5FJ8 L;  3HOU L;  2NVT L;  2R7Z L;  3H0G L;  3GTL L;  1I3Q L;  3H3V M;  2E2H L;  4C3J L;  3S1R L;  2JA5 L;  4C2M 1;  3HOW L;  4BY1 L;  5IP7 L;  3S14 L;  2NVQ L;  4A3G L;  4BBR L;  3GTG L;  4A93 L;  4A3E L;  3S17 L;  4A3C L;  3FKI L;  5M5Y L;  4C3I L;  2JA8 L;  3S1Q L;  3K7A L;  3GTJ L;  3HOX L;  4BY7 L;  4BXX L;  5IYD L;  4A3L L;  4Y7N L;  4AYB P;  2B63 L;  2PMZ P;  1Y1V L;  2JA6 L;  5M3M L;  3HOY L;  3M3Y L;  3GTO L;  4A3M L;  3GTK L;  1I50 L;  3HOZ L;  4A3I L;  1TWH L;  2NVY L;  3S16 L;  3S1N L;  1WCM L;  1TWG L;  3M4O L;  5IYB L;  4QIW P;  3PO3 L;  4X6A L;  5C44 L;  3RZD L;  4Y52 L;  5IP9 L;  2YU9 L;  1TWC L;  5M5X L;  5IYC L;  3GTM L;  3S1M L;  4A3D L;  1K83 L;  5C4X L;  3HOV L;  3S15 L;  5M5W L;  1R9T L;  3S2H L;  2R93 L;  2R92 L; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...