5C4JL

Crystal structure of a transcribing rna polymerase ii complex reveals a complete transcription bubble
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
43
structure length
43
Chain Sequence
KYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
pubmed doi rcsb
molecule tags Transferase/dna/rna
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 3
structure length 43
sequence length 43
ec nomenclature
pdb deposition date 2015-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 5c4jL00
4AYBP 4C2M1 1Y1WL 3S1NL 5C44L 5M5XL 3HKZP 2PMZP 4Y52L 3HOWL 3S2HL 2WAQP 2JA7L 4A3LL 4X6AL 3H0GL 4A3KL 5M3ML 2E2IL 3GTQL 4A3BL 5C4JL 3S15L 1TWCL 3HOYL 4A3DL 3GTLL 3RZOL 5C3EL 2YU9L 4C3IL 3GTOL 3K7AL 4C3JL 3S1QL 5IYCL 2VUML 4Y7NL 3S2DL 3GTGL 4BXXL 4A93L 2Y0SP 3S1RL 4BBSL 1TWAL 3H3VM 3PO2L 3S1ML 3S14L 3HOXL 3GTJL 3I4ML 5M5WL 5M3FL 5IYDL 4A3CL 3S16L 2WB1P 3GTML 5FLML 5M5YL 5FJ8L 2R92L 2B63L 3GTKL 3PO3L 1SFOL 2JA8L 4A3FL 4A3JL 3HOZL 2NVTL 1TWFL 4A3ML 1Y1VL 3CQZL 3RZDL 1K83L 2R93L 1I50L 3M4OL 2JA6L 4BY7L 3M3YL 1TWGL 1WCML 3HOVL 4BBRL 4BY1L 2E2JL 1R9TL 3FKIL 1TWHL 2E2HL 3S17L 3GTPL 3I4NL 5IP9L 2NVQL 2NVYL 4QIWP 5IP7L 2JA5L 1I6HL 4A3IL 5C4XL 2NVXL 3HOUL 5IYBL 4A3EL 4A3GL 4C3HL 2R7ZL 1I3QL
chains in the Genus database with same CATH superfamily
1B71A 4C2M1 2AUSB 1C09A 1PFWA 1E8JA 3LNLA 1VZIA 3B08B 3PIP1 3S2HL 2WAQP 2JA7L 1FHHA 2PVXA 1BE7A 3KYVA 5C4JL 3RZTA 2XJUA 4K9FA 1R0GA 5EIOC 1NXGA 3KYUA 2BE5D 1YV1A 2M4YA 2V3BB 5IYCL 4Y7NL 3S2DL 2A6ED 4A93L 4UY81 2Y0SP 3S1RL 3LWQB 3PO2L 1LTLA 1T9PA 2J9UB 5M5WL 5IYDL 3GTML 5FLML 2JI2A 5FJ8L 1IROA 3H9CA 2PSMC 3KYWA 1F4LA 3PKJA 2ZIXA 4LHLA 1VZGA 3NFPI 4AHYA 3HOZL 4TPUA 1Y1VL 3PL5A 3RZDL 1WJVA 4AI0A 2C6AA 1I50L 2HVYC 4TVMA 1WCML 4B8CD 1T9QA 3B0AB 1TWHL 3S17L 3H99A 3I4NL 3MQKB 1SMWA 1PFUA 2JA5L 5AI3A 4A3EL 1LKOA 1LKMA 4JADA 4C3HL 2M6PA 2R7ZL 4YWMA 7RXNA 1B2OA 1I3QL 1SMUA 3K35A 1PFVA 3S1NL 3HKZP 2A69D 2V0EA 2A6HD 4A3LL 1YUXA 1IU6A 3H0GL 4A3KL 2M6OA 1TWCL 1R0IA 8RXNA 5JVH1 3GTLL 5C3EL 2YU9L 2APOB 4ZN1B 2XJTA 5MGNA 1CAAA 3K7AL 1YUZA 4C3JL 4AI2A 4BXXL 3KYYA 4BBSL 4POFA 2C6BA 2PYAA 1TWAL 3H3VM 3S1ML 3HJYB 3I4ML 3HJWB 3S16L 4ZN3B 5M5YL 1YK5A 3MSUA 1DX8A 4E6YA 1H7VA 3QVDA 3WWNB 1IW7D 2NVTL 4A3ML 3M4OL 5GAHc 1B13A 2XJRA 5MFZA 1TWGL 1OWBA 2GMGA 3RYGA 5RXNA 4AI1A 2E2JL 4JAGA 1R9TL 2PPTA 2LCQA 1JYBA 1NXEA 2NVQL 2H12A 2QL0A 5IP7L 3LPEB 4A3IL 1FHMA 2NVXL 1Z92B 3HOUL 2XJQA 4AR6A 3LWRB 5JVG1 4A3GL 3PWFA 3LWPB 2AQCA 4AYBP 3PIO1 2B5ID 1Y1WL 5C44L 5H1Sc 4Y52L 1RWDA 1BQ9A 1T9OA 2RFKB 2CKCA 1CADA 4U671 5GAEc 4AHWA 5M3ML 3ZG6A 2RDVA 1ODHA 3GTQL 3MPSA 1S30A 3HOYL 1PZXA 2M4VA 2KKDA 1YK4A 6RXNA 2K2DA 2XJSA 3LWOB 4WFN1 3S1QL 3PZAA 2VUML 3LWVB 5IY0A 1DVBA 5MLC3 1BQ8A 3J7Y1 2XJVA 1QYBA 4JAFA 5M3FL 1R0FA 1PFYA 4A3CL 4RXNA 2WB1P 4ME3A 2R92L 2XJPA 3FDJA 4V196 1S24A 1RYTA 2PVEA 1RB9A 4AHXA 3GTKL 3RZ6A 1SFOL 3VPBE 2JA8L 2Z3RB 3HAXC 1TWFL 1K83L 2CR8A 1IRNA 4GS7D 1R0JA 2DSXA 3M3YL 2NYDA 3HOVL 4BBRL 3FKIL 2E2HL 5IP9L 2NVYL 1QQTA 1ZRPA 4XXBB 3P8BA 1I6HL 3H97A 2O5JD 3SS2A 5IYBL 2CKAA 2L0ZA 5M5XL 2HR5A 2A68D 2PMZP 3HOWL 5DM61 2AYJA 2EY4E 5DM71 4X6AL 5EINC 1VZHA 2E2IL 5MFPA 4A3BL 3S15L 2ERSA 4A3DL 1B2JA 3RZOL 4POGA 1P7PA 4AR5A 4C3IL 1RDGA 3GTOL 2JI1A 1BRFA 1QCVA 1RYQA 4YWLA 4AHZA 1BFYA 3GTGL 4XGHA 3P2AA 3IU3I 3WWLA 3S14L 3HOXL 3GTJL 1LKPA 2ERJA 5GAGc 2KN9A 1RDVA 1OWCA 1R0HA 3A44A 5GADc 2B63L 4LHNA 1IU5A 2VL6A 3PO3L 2MS3A 4A3FL 4A3JL 4G6BA 4JAEA 3QQCE 3CQZL 2R93L 2Z3QB 2JA6L 1SMMA 4BY7L 3H9BA 4AI3A 3PKIA 2V0FA 2JI3A 5K2ME 3JR7A 4BY1L 4AR3A 1S2ZA 3GTPL 1NNQA 1VCXA 5MF6A 4QIWP 3KYXA 5C4XL 5AN9H 5AI2A 4AR4A 3J7Z1
chains in the Genus database with same CATH topology
4AYBP 4C2M1 1Y1WL 3S1NL 5C44L 5M5XL 3HKZP 2PMZP 4Y52L 3HOWL 3S2HL 2WAQP 2JA7L 4A3LL 4X6AL 3H0GL 4A3KL 5M3ML 2E2IL 3GTQL 4A3BL 5C4JL 3S15L 1TWCL 3HOYL 4A3DL 3GTLL 3RZOL 5C3EL 2YU9L 4C3IL 3GTOL 3K7AL 4C3JL 3S1QL 5IYCL 2VUML 4Y7NL 3S2DL 3GTGL 4BXXL 4A93L 2Y0SP 3S1RL 4BBSL 1TWAL 3H3VM 3PO2L 3S1ML 3S14L 3HOXL 3GTJL 3I4ML 5M5WL 5M3FL 5IYDL 4A3CL 3S16L 2WB1P 3GTML 5FLML 5M5YL 5FJ8L 2R92L 2B63L 3GTKL 3PO3L 1SFOL 2JA8L 4A3FL 4A3JL 3HOZL 2NVTL 1TWFL 4A3ML 1Y1VL 3CQZL 3RZDL 1K83L 2R93L 1I50L 3M4OL 2JA6L 4BY7L 3M3YL 1TWGL 1WCML 3HOVL 4BBRL 4BY1L 2E2JL 1R9TL 3FKIL 1TWHL 2E2HL 3S17L 3GTPL 3I4NL 5IP9L 2NVQL 2NVYL 4QIWP 5IP7L 2JA5L 1I6HL 4A3IL 5C4XL 2NVXL 3HOUL 5IYBL 4A3EL 4A3GL 4C3HL 2R7ZL 1I3QL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AYB P;  4C2M 1;  1Y1W L;  3S1N L;  5C44 L;  5M5X L;  3HKZ P;  2PMZ P;  4Y52 L;  3HOW L;  3S2H L;  2WAQ P;  2JA7 L;  4A3L L;  4X6A L;  3H0G L;  4A3K L;  5M3M L;  2E2I L;  3GTQ L;  4A3B L;  5C4J L;  3S15 L;  1TWC L;  3HOY L;  4A3D L;  3GTL L;  3RZO L;  5C3E L;  2YU9 L;  4C3I L;  3GTO L;  3K7A L;  4C3J L;  3S1Q L;  5IYC L;  2VUM L;  4Y7N L;  3S2D L;  3GTG L;  4BXX L;  4A93 L;  2Y0S P;  3S1R L;  4BBS L;  1TWA L;  3H3V M;  3PO2 L;  3S1M L;  3S14 L;  3HOX L;  3GTJ L;  3I4M L;  5M5W L;  5M3F L;  5IYD L;  4A3C L;  3S16 L;  2WB1 P;  3GTM L;  5FLM L;  5M5Y L;  5FJ8 L;  2R92 L;  2B63 L;  3GTK L;  3PO3 L;  1SFO L;  2JA8 L;  4A3F L;  4A3J L;  3HOZ L;  2NVT L;  1TWF L;  4A3M L;  1Y1V L;  3CQZ L;  3RZD L;  1K83 L;  2R93 L;  1I50 L;  3M4O L;  2JA6 L;  4BY7 L;  3M3Y L;  1TWG L;  1WCM L;  3HOV L;  4BBR L;  4BY1 L;  2E2J L;  1R9T L;  3FKI L;  1TWH L;  2E2H L;  3S17 L;  3GTP L;  3I4N L;  5IP9 L;  2NVQ L;  2NVY L;  4QIW P;  5IP7 L;  2JA5 L;  1I6H L;  4A3I L;  5C4X L;  2NVX L;  3HOU L;  5IYB L;  4A3E L;  4A3G L;  4C3H L;  2R7Z L;  1I3Q L; 
#chains in the Genus database with same CATH topology
 1B71 A;  4C2M 1;  2AUS B;  1C09 A;  1PFW A;  1E8J A;  3LNL A;  1VZI A;  3B08 B;  3PIP 1;  3S2H L;  2WAQ P;  2JA7 L;  1FHH A;  2PVX A;  1BE7 A;  3KYV A;  5C4J L;  3RZT A;  2XJU A;  4K9F A;  1R0G A;  5EIO C;  1NXG A;  3KYU A;  2BE5 D;  1YV1 A;  2M4Y A;  2V3B B;  5IYC L;  4Y7N L;  3S2D L;  2A6E D;  4A93 L;  4UY8 1;  2Y0S P;  3S1R L;  3LWQ B;  3PO2 L;  1LTL A;  1T9P A;  2J9U B;  5M5W L;  5IYD L;  3GTM L;  5FLM L;  2JI2 A;  5FJ8 L;  1IRO A;  3H9C A;  2PSM C;  3KYW A;  1F4L A;  3PKJ A;  2ZIX A;  4LHL A;  1VZG A;  3NFP I;  4AHY A;  3HOZ L;  4TPU A;  1Y1V L;  3PL5 A;  3RZD L;  1WJV A;  4AI0 A;  2C6A A;  1I50 L;  2HVY C;  4TVM A;  1WCM L;  4B8C D;  1T9Q A;  3B0A B;  1TWH L;  3S17 L;  3H99 A;  3I4N L;  3MQK B;  1SMW A;  1PFU A;  2JA5 L;  5AI3 A;  4A3E L;  1LKO A;  1LKM A;  4JAD A;  4C3H L;  2M6P A;  2R7Z L;  4YWM A;  7RXN A;  1B2O A;  1I3Q L;  1SMU A;  3K35 A;  1PFV A;  3S1N L;  3HKZ P;  2A69 D;  2V0E A;  2A6H D;  4A3L L;  1YUX A;  1IU6 A;  3H0G L;  4A3K L;  2M6O A;  1TWC L;  1R0I A;  8RXN A;  5JVH 1;  3GTL L;  5C3E L;  2YU9 L;  2APO B;  4ZN1 B;  2XJT A;  5MGN A;  1CAA A;  3K7A L;  1YUZ A;  4C3J L;  4AI2 A;  4BXX L;  3KYY A;  4BBS L;  4POF A;  2C6B A;  2PYA A;  1TWA L;  3H3V M;  3S1M L;  3HJY B;  3I4M L;  3HJW B;  3S16 L;  4ZN3 B;  5M5Y L;  1YK5 A;  3MSU A;  1DX8 A;  4E6Y A;  1H7V A;  3QVD A;  3WWN B;  1IW7 D;  2NVT L;  4A3M L;  3M4O L;  5GAH c;  1B13 A;  2XJR A;  5MFZ A;  1TWG L;  1OWB A;  2GMG A;  3RYG A;  5RXN A;  4AI1 A;  2E2J L;  4JAG A;  1R9T L;  2PPT A;  2LCQ A;  1JYB A;  1NXE A;  2NVQ L;  2H12 A;  2QL0 A;  5IP7 L;  3LPE B;  4A3I L;  1FHM A;  2NVX L;  1Z92 B;  3HOU L;  2XJQ A;  4AR6 A;  3LWR B;  5JVG 1;  4A3G L;  3PWF A;  3LWP B;  2AQC A;  4AYB P;  3PIO 1;  2B5I D;  1Y1W L;  5C44 L;  5H1S c;  4Y52 L;  1RWD A;  1BQ9 A;  1T9O A;  2RFK B;  2CKC A;  1CAD A;  4U67 1;  5GAE c;  4AHW A;  5M3M L;  3ZG6 A;  2RDV A;  1ODH A;  3GTQ L;  3MPS A;  1S30 A;  3HOY L;  1PZX A;  2M4V A;  2KKD A;  1YK4 A;  6RXN A;  2K2D A;  2XJS A;  3LWO B;  4WFN 1;  3S1Q L;  3PZA A;  2VUM L;  3LWV B;  5IY0 A;  1DVB A;  5MLC 3;  1BQ8 A;  3J7Y 1;  2XJV A;  1QYB A;  4JAF A;  5M3F L;  1R0F A;  1PFY A;  4A3C L;  4RXN A;  2WB1 P;  4ME3 A;  2R92 L;  2XJP A;  3FDJ A;  4V19 6;  1S24 A;  1RYT A;  2PVE A;  1RB9 A;  4AHX A;  3GTK L;  3RZ6 A;  1SFO L;  3VPB E;  2JA8 L;  2Z3R B;  3HAX C;  1TWF L;  1K83 L;  2CR8 A;  1IRN A;  4GS7 D;  1R0J A;  2DSX A;  3M3Y L;  2NYD A;  3HOV L;  4BBR L;  3FKI L;  2E2H L;  5IP9 L;  2NVY L;  1QQT A;  1ZRP A;  4XXB B;  3P8B A;  1I6H L;  3H97 A;  2O5J D;  3SS2 A;  5IYB L;  2CKA A;  2L0Z A;  5M5X L;  2HR5 A;  2A68 D;  2PMZ P;  3HOW L;  5DM6 1;  2AYJ A;  2EY4 E;  5DM7 1;  4X6A L;  5EIN C;  1VZH A;  2E2I L;  5MFP A;  4A3B L;  3S15 L;  2ERS A;  4A3D L;  1B2J A;  3RZO L;  4POG A;  1P7P A;  4AR5 A;  4C3I L;  1RDG A;  3GTO L;  2JI1 A;  1BRF A;  1QCV A;  1RYQ A;  4YWL A;  4AHZ A;  1BFY A;  3GTG L;  4XGH A;  3P2A A;  3IU3 I;  3WWL A;  3S14 L;  3HOX L;  3GTJ L;  1LKP A;  2ERJ A;  5GAG c;  2KN9 A;  1RDV A;  1OWC A;  1R0H A;  3A44 A;  5GAD c;  2B63 L;  4LHN A;  1IU5 A;  2VL6 A;  3PO3 L;  2MS3 A;  4A3F L;  4A3J L;  4G6B A;  4JAE A;  3QQC E;  3CQZ L;  2R93 L;  2Z3Q B;  2JA6 L;  1SMM A;  4BY7 L;  3H9B A;  4AI3 A;  3PKI A;  2V0F A;  2JI3 A;  5K2M E;  3JR7 A;  4BY1 L;  4AR3 A;  1S2Z A;  3GTP L;  1NNQ A;  1VCX A;  5MF6 A;  4QIW P;  3KYX A;  5C4X L;  5AN9 H;  5AI2 A;  4AR4 A;  3J7Z 1; 
#chains in the Genus database with same CATH homology
 4AYB P;  4C2M 1;  1Y1W L;  3S1N L;  5C44 L;  5M5X L;  3HKZ P;  2PMZ P;  4Y52 L;  3HOW L;  3S2H L;  2WAQ P;  2JA7 L;  4A3L L;  4X6A L;  3H0G L;  4A3K L;  5M3M L;  2E2I L;  3GTQ L;  4A3B L;  5C4J L;  3S15 L;  1TWC L;  3HOY L;  4A3D L;  3GTL L;  3RZO L;  5C3E L;  2YU9 L;  4C3I L;  3GTO L;  3K7A L;  4C3J L;  3S1Q L;  5IYC L;  2VUM L;  4Y7N L;  3S2D L;  3GTG L;  4BXX L;  4A93 L;  2Y0S P;  3S1R L;  4BBS L;  1TWA L;  3H3V M;  3PO2 L;  3S1M L;  3S14 L;  3HOX L;  3GTJ L;  3I4M L;  5M5W L;  5M3F L;  5IYD L;  4A3C L;  3S16 L;  2WB1 P;  3GTM L;  5FLM L;  5M5Y L;  5FJ8 L;  2R92 L;  2B63 L;  3GTK L;  3PO3 L;  1SFO L;  2JA8 L;  4A3F L;  4A3J L;  3HOZ L;  2NVT L;  1TWF L;  4A3M L;  1Y1V L;  3CQZ L;  3RZD L;  1K83 L;  2R93 L;  1I50 L;  3M4O L;  2JA6 L;  4BY7 L;  3M3Y L;  1TWG L;  1WCM L;  3HOV L;  4BBR L;  4BY1 L;  2E2J L;  1R9T L;  3FKI L;  1TWH L;  2E2H L;  3S17 L;  3GTP L;  3I4N L;  5IP9 L;  2NVQ L;  2NVY L;  4QIW P;  5IP7 L;  2JA5 L;  1I6H L;  4A3I L;  5C4X L;  2NVX L;  3HOU L;  5IYB L;  4A3E L;  4A3G L;  4C3H L;  2R7Z L;  1I3Q L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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