5FLML

Structure of transcribing mammalian rna polymerase ii
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
44
structure length
44
Chain Sequence
MIYICGECHTENEIKSRDPIRCRECGYRIMYKKRTKRLVVFDAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of Transcribing Mammalian RNA Polymerase II
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE
total genus 1
structure length 44
sequence length 44
ec nomenclature
pdb deposition date 2015-10-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 5flmL00
4C3JL 1I6HL 5C4XL 5IYDL 3S1QL 2NVTL 1TWFL 5FJ8L 1SFOL 1TWCL 2WB1P 3FKIL 5C3EL 1I3QL 5M3FL 4AYBP 5M5WL 3RZDL 3GTLL 3I4NL 3S1RL 4C2M1 2JA6L 4BY1L 3S14L 3RZOL 4A3KL 1Y1VL 4BBSL 5FLML 1TWHL 5M5XL 2NVXL 2NVQL 4Y7NL 5M3ML 3S2HL 1R9TL 2PMZP 1K83L 4A3FL 3HOYL 3S1ML 4BXXL 3GTOL 5IP9L 3HOZL 5C4JL 3M4OL 3K7AL 4Y52L 2R93L 4A3CL 3I4ML 3HOXL 2E2HL 4A3ML 1TWGL 3S2DL 3GTML 2JA5L 5M5YL 1Y1WL 2WAQP 2YU9L 3H3VM 4X6AL 2JA7L 4A93L 1I50L 3PO3L 3HOWL 4A3EL 4A3JL 3CQZL 3GTQL 2VUML 2B63L 4A3GL 2R92L 4A3BL 3PO2L 3GTPL 3GTKL 4A3DL 2E2IL 1TWAL 2R7ZL 2E2JL 2NVYL 4A3LL 2Y0SP 5IYBL 3S15L 4BBRL 4A3IL 3H0GL 3S17L 4BY7L 4C3IL 1WCML 3HOVL 3S16L 5IP7L 3S1NL 3GTGL 2JA8L 3HOUL 4QIWP 3HKZP 5IYCL 3M3YL 5C44L 4C3HL 3GTJL
chains in the Genus database with same CATH superfamily
3PWFA 2B5ID 2XJRA 2APOB 2PVXA 2KN9A 4ME3A 2V0EA 2K2DA 3S1QL 1PFVA 4AHZA 2JI2A 1SFOL 5JVG1 4JAGA 5DM61 5M3FL 1NXEA 3LWOB 6RXNA 2A6ED 3MSUA 4BBSL 2A68D 3KYUA 2NVXL 1NXGA 1R9TL 5IY0A 4U671 2RDVA 1VCXA 2M6OA 1T9OA 5IP9L 4XXBB 3LPEB 3PKJA 5GAGc 1DVBA 3MPSA 3K7AL 2HR5A 4TPUA 4A3CL 1NNQA 3H97A 4AHYA 2E2HL 2AQCA 3GTML 2WAQP 4A93L 1I50L 1YUXA 2JI1A 2PPTA 4A3GL 1LTLA 4A3DL 1BQ9A 3WWLA 1TWAL 2A69D 5RXNA 4K9FA 2E2JL 2GMGA 2Z3RB 1RWDA 4RXNA 1BRFA 2XJUA 5DM71 2V0FA 4AI3A 3HJWB 4C3IL 3S16L 3HOUL 2ERJA 4AR3A 4WFN1 4AR4A 3M3YL 1RDGA 1R0FA 4JADA 1B2OA 4POFA 1Z92B 4AR5A 1C09A 1RB9A 1IRNA 1I6HL 5C4XL 5IYDL 1ODHA 2H12A 1SMMA 3LNLA 3ZG6A 1FHHA 2CR8A 2AUSB 3GTLL 4ZN3B 3WWNB 4BY1L 1Y1VL 1YUZA 2L0ZA 5M5XL 1CADA 1RYQA 3S2HL 1H7VA 4UY81 7RXNA 3HOYL 3S1ML 1E8JA 4BXXL 3GTOL 2Z3QB 3H99A 3MQKB 1T9PA 4Y52L 3HOXL 4A3ML 1Y1WL 2YU9L 4YWLA 3RZTA 4AI1A 3KYYA 3PO3L 2HVYC 4A3EL 3CQZL 3GTQL 2VUML 2B63L 2ERSA 2XJVA 2R92L 3KYXA 3PO2L 3GTKL 1R0IA 1B71A 3SS2A 4YWMA 2E2IL 4E6YA 3QVDA 2R7ZL 2BE5D 2V3BB 1R0JA 2JI3A 3P2AA 4BBRL 3H0GL 5K2ME 4ZN1B 3S17L 4BY7L 1YK4A 3PZAA 1WCML 5GAEc 3HOVL 1SMWA 3S1NL 3H9CA 1BE7A 5IYCL 1BFYA 1WJVA 3KYVA 5C44L 3GTJL 2DSXA 1LKOA 1QYBA 4LHNA 2C6AA 3LWVB 2AYJA 3LWPB 1PFYA 3RYGA 2NVTL 5MFPA 5MF6A 1IW7D 4XGHA 1DX8A 3FKIL 1I3QL 3RZDL 4AYBP 5M5WL 1FHMA 5GADc 3I4NL 2PVEA 3S1RL 2JA6L 5H1Sc 3S14L 4A3KL 2PSMC 2NVQL 4Y7NL 5EIOC 1SMUA 3PIP1 1K83L 1PFUA 5C4JL 4JAEA 1VZIA 3P8BA 2R93L 1RYTA 2J9UB 3I4ML 3S2DL 4AHWA 2XJTA 4X6AL 2JA7L 1IU5A 5AI2A 1YV1A 3J7Z1 3HOWL 3B0AB 2ZIXA 2PYAA 3QQCE 3J7Y1 1VZGA 1S30A 2Y0SP 3S15L 4A3IL 3RZ6A 2EY4E 4AI0A 1LKPA 4AI2A 1R0HA 2MS3A 5IP7L 3GTGL 4QIWP 2A6HD 1OWBA 3PL5A 4C3HL 5AN9H 3KYWA 4B8CD 4C3JL 3K35A 1F4LA 3JR7A 1TWFL 5FJ8L 4G6BA 4AHXA 1TWCL 2WB1P 3IU3I 5C3EL 2XJPA 8RXNA 4C2M1 1R0GA 3PKIA 4TVMA 2M4YA 3RZOL 5JVH1 5GAHc 5FLML 1TWHL 1LKMA 5M3ML 4POGA 1T9QA 4JAFA 2XJSA 2PMZP 1PFWA 4A3FL 1JYBA 3HOZL 1PZXA 2NYDA 3M4OL 1VZHA 3A44A 3HAXC 1TWGL 1YK5A 5M5YL 1S24A 2JA5L 2QL0A 3H9BA 1BQ8A 3LWQB 3FDJA 3H3VM 3PIO1 1RDVA 5MFZA 2O5JD 4A3JL 2KKDA 2CKAA 3B08B 2C6BA 1ZRPA 1CAAA 4A3BL 3HJYB 5AI3A 3GTPL 1QQTA 1IU6A 1OWCA 4AR6A 3VPBE 1P7PA 2CKCA 2NVYL 4A3LL 5IYBL 2LCQA 5EINC 4LHLA 5MGNA 2XJQA 2M4VA 4GS7D 2M6PA 1B13A 1B2JA 1IROA 2RFKB 2JA8L 3HKZP 2VL6A 4V196 1S2ZA 3LWRB 3NFPI 1QCVA 5MLC3
chains in the Genus database with same CATH topology
4C3JL 1I6HL 5C4XL 5IYDL 3S1QL 2NVTL 1TWFL 5FJ8L 1SFOL 1TWCL 2WB1P 3FKIL 5C3EL 1I3QL 5M3FL 4AYBP 5M5WL 3RZDL 3GTLL 3I4NL 3S1RL 4C2M1 2JA6L 4BY1L 3S14L 3RZOL 4A3KL 1Y1VL 4BBSL 5FLML 1TWHL 5M5XL 2NVXL 2NVQL 4Y7NL 5M3ML 3S2HL 1R9TL 2PMZP 1K83L 4A3FL 3HOYL 3S1ML 4BXXL 3GTOL 5IP9L 3HOZL 5C4JL 3M4OL 3K7AL 4Y52L 2R93L 4A3CL 3I4ML 3HOXL 2E2HL 4A3ML 1TWGL 3S2DL 3GTML 2JA5L 5M5YL 1Y1WL 2WAQP 2YU9L 3H3VM 4X6AL 2JA7L 4A93L 1I50L 3PO3L 3HOWL 4A3EL 4A3JL 3CQZL 3GTQL 2VUML 2B63L 4A3GL 2R92L 4A3BL 3PO2L 3GTPL 3GTKL 4A3DL 2E2IL 1TWAL 2R7ZL 2E2JL 2NVYL 4A3LL 2Y0SP 5IYBL 3S15L 4BBRL 4A3IL 3H0GL 3S17L 4BY7L 4C3IL 1WCML 3HOVL 3S16L 5IP7L 3S1NL 3GTGL 2JA8L 3HOUL 4QIWP 3HKZP 5IYCL 3M3YL 5C44L 4C3HL 3GTJL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4C3J L;  1I6H L;  5C4X L;  5IYD L;  3S1Q L;  2NVT L;  1TWF L;  5FJ8 L;  1SFO L;  1TWC L;  2WB1 P;  3FKI L;  5C3E L;  1I3Q L;  5M3F L;  4AYB P;  5M5W L;  3RZD L;  3GTL L;  3I4N L;  3S1R L;  4C2M 1;  2JA6 L;  4BY1 L;  3S14 L;  3RZO L;  4A3K L;  1Y1V L;  4BBS L;  5FLM L;  1TWH L;  5M5X L;  2NVX L;  2NVQ L;  4Y7N L;  5M3M L;  3S2H L;  1R9T L;  2PMZ P;  1K83 L;  4A3F L;  3HOY L;  3S1M L;  4BXX L;  3GTO L;  5IP9 L;  3HOZ L;  5C4J L;  3M4O L;  3K7A L;  4Y52 L;  2R93 L;  4A3C L;  3I4M L;  3HOX L;  2E2H L;  4A3M L;  1TWG L;  3S2D L;  3GTM L;  2JA5 L;  5M5Y L;  1Y1W L;  2WAQ P;  2YU9 L;  3H3V M;  4X6A L;  2JA7 L;  4A93 L;  1I50 L;  3PO3 L;  3HOW L;  4A3E L;  4A3J L;  3CQZ L;  3GTQ L;  2VUM L;  2B63 L;  4A3G L;  2R92 L;  4A3B L;  3PO2 L;  3GTP L;  3GTK L;  4A3D L;  2E2I L;  1TWA L;  2R7Z L;  2E2J L;  2NVY L;  4A3L L;  2Y0S P;  5IYB L;  3S15 L;  4BBR L;  4A3I L;  3H0G L;  3S17 L;  4BY7 L;  4C3I L;  1WCM L;  3HOV L;  3S16 L;  5IP7 L;  3S1N L;  3GTG L;  2JA8 L;  3HOU L;  4QIW P;  3HKZ P;  5IYC L;  3M3Y L;  5C44 L;  4C3H L;  3GTJ L; 
#chains in the Genus database with same CATH topology
 3PWF A;  2B5I D;  2XJR A;  2APO B;  2PVX A;  2KN9 A;  4ME3 A;  2V0E A;  2K2D A;  3S1Q L;  1PFV A;  4AHZ A;  2JI2 A;  1SFO L;  5JVG 1;  4JAG A;  5DM6 1;  5M3F L;  1NXE A;  3LWO B;  6RXN A;  2A6E D;  3MSU A;  4BBS L;  2A68 D;  3KYU A;  2NVX L;  1NXG A;  1R9T L;  5IY0 A;  4U67 1;  2RDV A;  1VCX A;  2M6O A;  1T9O A;  5IP9 L;  4XXB B;  3LPE B;  3PKJ A;  5GAG c;  1DVB A;  3MPS A;  3K7A L;  2HR5 A;  4TPU A;  4A3C L;  1NNQ A;  3H97 A;  4AHY A;  2E2H L;  2AQC A;  3GTM L;  2WAQ P;  4A93 L;  1I50 L;  1YUX A;  2JI1 A;  2PPT A;  4A3G L;  1LTL A;  4A3D L;  1BQ9 A;  3WWL A;  1TWA L;  2A69 D;  5RXN A;  4K9F A;  2E2J L;  2GMG A;  2Z3R B;  1RWD A;  4RXN A;  1BRF A;  2XJU A;  5DM7 1;  2V0F A;  4AI3 A;  3HJW B;  4C3I L;  3S16 L;  3HOU L;  2ERJ A;  4AR3 A;  4WFN 1;  4AR4 A;  3M3Y L;  1RDG A;  1R0F A;  4JAD A;  1B2O A;  4POF A;  1Z92 B;  4AR5 A;  1C09 A;  1RB9 A;  1IRN A;  1I6H L;  5C4X L;  5IYD L;  1ODH A;  2H12 A;  1SMM A;  3LNL A;  3ZG6 A;  1FHH A;  2CR8 A;  2AUS B;  3GTL L;  4ZN3 B;  3WWN B;  4BY1 L;  1Y1V L;  1YUZ A;  2L0Z A;  5M5X L;  1CAD A;  1RYQ A;  3S2H L;  1H7V A;  4UY8 1;  7RXN A;  3HOY L;  3S1M L;  1E8J A;  4BXX L;  3GTO L;  2Z3Q B;  3H99 A;  3MQK B;  1T9P A;  4Y52 L;  3HOX L;  4A3M L;  1Y1W L;  2YU9 L;  4YWL A;  3RZT A;  4AI1 A;  3KYY A;  3PO3 L;  2HVY C;  4A3E L;  3CQZ L;  3GTQ L;  2VUM L;  2B63 L;  2ERS A;  2XJV A;  2R92 L;  3KYX A;  3PO2 L;  3GTK L;  1R0I A;  1B71 A;  3SS2 A;  4YWM A;  2E2I L;  4E6Y A;  3QVD A;  2R7Z L;  2BE5 D;  2V3B B;  1R0J A;  2JI3 A;  3P2A A;  4BBR L;  3H0G L;  5K2M E;  4ZN1 B;  3S17 L;  4BY7 L;  1YK4 A;  3PZA A;  1WCM L;  5GAE c;  3HOV L;  1SMW A;  3S1N L;  3H9C A;  1BE7 A;  5IYC L;  1BFY A;  1WJV A;  3KYV A;  5C44 L;  3GTJ L;  2DSX A;  1LKO A;  1QYB A;  4LHN A;  2C6A A;  3LWV B;  2AYJ A;  3LWP B;  1PFY A;  3RYG A;  2NVT L;  5MFP A;  5MF6 A;  1IW7 D;  4XGH A;  1DX8 A;  3FKI L;  1I3Q L;  3RZD L;  4AYB P;  5M5W L;  1FHM A;  5GAD c;  3I4N L;  2PVE A;  3S1R L;  2JA6 L;  5H1S c;  3S14 L;  4A3K L;  2PSM C;  2NVQ L;  4Y7N L;  5EIO C;  1SMU A;  3PIP 1;  1K83 L;  1PFU A;  5C4J L;  4JAE A;  1VZI A;  3P8B A;  2R93 L;  1RYT A;  2J9U B;  3I4M L;  3S2D L;  4AHW A;  2XJT A;  4X6A L;  2JA7 L;  1IU5 A;  5AI2 A;  1YV1 A;  3J7Z 1;  3HOW L;  3B0A B;  2ZIX A;  2PYA A;  3QQC E;  3J7Y 1;  1VZG A;  1S30 A;  2Y0S P;  3S15 L;  4A3I L;  3RZ6 A;  2EY4 E;  4AI0 A;  1LKP A;  4AI2 A;  1R0H A;  2MS3 A;  5IP7 L;  3GTG L;  4QIW P;  2A6H D;  1OWB A;  3PL5 A;  4C3H L;  5AN9 H;  3KYW A;  4B8C D;  4C3J L;  3K35 A;  1F4L A;  3JR7 A;  1TWF L;  5FJ8 L;  4G6B A;  4AHX A;  1TWC L;  2WB1 P;  3IU3 I;  5C3E L;  2XJP A;  8RXN A;  4C2M 1;  1R0G A;  3PKI A;  4TVM A;  2M4Y A;  3RZO L;  5JVH 1;  5GAH c;  5FLM L;  1TWH L;  1LKM A;  5M3M L;  4POG A;  1T9Q A;  4JAF A;  2XJS A;  2PMZ P;  1PFW A;  4A3F L;  1JYB A;  3HOZ L;  1PZX A;  2NYD A;  3M4O L;  1VZH A;  3A44 A;  3HAX C;  1TWG L;  1YK5 A;  5M5Y L;  1S24 A;  2JA5 L;  2QL0 A;  3H9B A;  1BQ8 A;  3LWQ B;  3FDJ A;  3H3V M;  3PIO 1;  1RDV A;  5MFZ A;  2O5J D;  4A3J L;  2KKD A;  2CKA A;  3B08 B;  2C6B A;  1ZRP A;  1CAA A;  4A3B L;  3HJY B;  5AI3 A;  3GTP L;  1QQT A;  1IU6 A;  1OWC A;  4AR6 A;  3VPB E;  1P7P A;  2CKC A;  2NVY L;  4A3L L;  5IYB L;  2LCQ A;  5EIN C;  4LHL A;  5MGN A;  2XJQ A;  2M4V A;  4GS7 D;  2M6P A;  1B13 A;  1B2J A;  1IRO A;  2RFK B;  2JA8 L;  3HKZ P;  2VL6 A;  4V19 6;  1S2Z A;  3LWR B;  3NFP I;  1QCV A;  5MLC 3; 
#chains in the Genus database with same CATH homology
 4C3J L;  1I6H L;  5C4X L;  5IYD L;  3S1Q L;  2NVT L;  1TWF L;  5FJ8 L;  1SFO L;  1TWC L;  2WB1 P;  3FKI L;  5C3E L;  1I3Q L;  5M3F L;  4AYB P;  5M5W L;  3RZD L;  3GTL L;  3I4N L;  3S1R L;  4C2M 1;  2JA6 L;  4BY1 L;  3S14 L;  3RZO L;  4A3K L;  1Y1V L;  4BBS L;  5FLM L;  1TWH L;  5M5X L;  2NVX L;  2NVQ L;  4Y7N L;  5M3M L;  3S2H L;  1R9T L;  2PMZ P;  1K83 L;  4A3F L;  3HOY L;  3S1M L;  4BXX L;  3GTO L;  5IP9 L;  3HOZ L;  5C4J L;  3M4O L;  3K7A L;  4Y52 L;  2R93 L;  4A3C L;  3I4M L;  3HOX L;  2E2H L;  4A3M L;  1TWG L;  3S2D L;  3GTM L;  2JA5 L;  5M5Y L;  1Y1W L;  2WAQ P;  2YU9 L;  3H3V M;  4X6A L;  2JA7 L;  4A93 L;  1I50 L;  3PO3 L;  3HOW L;  4A3E L;  4A3J L;  3CQZ L;  3GTQ L;  2VUM L;  2B63 L;  4A3G L;  2R92 L;  4A3B L;  3PO2 L;  3GTP L;  3GTK L;  4A3D L;  2E2I L;  1TWA L;  2R7Z L;  2E2J L;  2NVY L;  4A3L L;  2Y0S P;  5IYB L;  3S15 L;  4BBR L;  4A3I L;  3H0G L;  3S17 L;  4BY7 L;  4C3I L;  1WCM L;  3HOV L;  3S16 L;  5IP7 L;  3S1N L;  3GTG L;  2JA8 L;  3HOU L;  4QIW P;  3HKZ P;  5IYC L;  3M3Y L;  5C44 L;  4C3H L;  3GTJ L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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