5IYCL

Human core-pic in the initial transcribing state
Total Genus 0
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
0
sequence length
46
structure length
46
Chain Sequence
QPMIYICGECHTENEIKSRDPIRCRECGYRIMYKKRTKRLVVFDAR

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Near-atomic resolution visualization of human transcription promoter opening.
pubmed doi rcsb
molecule tags Transcription, transferase/dna
source organism Homo sapiens
molecule keywords DNA-directed RNA polymerase II subunit RPB1
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2016-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 5iycL00
2NVXL 4A3GL 1TWCL 1I3QL 4C3IL 5M5XL 1TWHL 2NVTL 3PO3L 3HOWL 5IYCL 1K83L 2NVQL 3HOVL 5M5YL 5M3FL 2R7ZL 2JA6L 3I4ML 3RZOL 2PMZP 1R9TL 5C44L 3HOYL 5IP7L 3GTGL 3GTQL 3GTJL 4C3JL 4C2M1 5FJ8L 3GTLL 4A3JL 4A3CL 4A3FL 3RZDL 2B63L 4A3DL 2WB1P 3GTKL 4BBRL 5IYBL 3S1NL 4BY7L 5IYDL 3FKIL 1Y1VL 3S14L 3S1ML 1Y1WL 1TWGL 3HOZL 4Y52L 2E2JL 4A3LL 3HOUL 3CQZL 3HOXL 3GTOL 4BBSL 5C3EL 1I50L 3H0GL 1I6HL 3S1RL 4C3HL 4A3EL 2WAQP 3HKZP 4BXXL 3M3YL 2Y0SP 1SFOL 4A3BL 2R93L 3M4OL 4BY1L 3S1QL 3S15L 3GTML 3S16L 5FLML 5M3ML 1TWAL 2NVYL 2VUML 4X6AL 1WCML 3K7AL 5C4XL 4QIWP 2YU9L 5M5WL 5IP9L 4A93L 4A3ML 4A3KL 2E2IL 3H3VM 3GTPL 3I4NL 3S2HL 1TWFL 2JA8L 4Y7NL 5C4JL 2E2HL 4AYBP 4A3IL 2R92L 3PO2L 2JA7L 2JA5L 3S17L 3S2DL
chains in the Genus database with same CATH superfamily
4A3GL 4YWMA 1YUZA 4AI1A 2AQCA 3WWNB 3PO3L 3JR7A 5M3FL 3RZOL 2PYAA 2K2DA 3P8BA 2AUSB 2MS3A 3GTGL 2PVEA 4AR4A 3PL5A 3KYWA 1NXGA 4JADA 5FJ8L 1IROA 1ODHA 2WB1P 4BBRL 1IU5A 3RZ6A 5IYDL 3S1ML 1YV1A 1TWGL 2APOB 2M4VA 1PFVA 2M6PA 4Y52L 1R0HA 2GMGA 3RZTA 4BBSL 5C3EL 4ME3A 4ZN1B 3J7Y1 2XJPA 3H97A 1NXEA 3PWFA 2O5JD 1VZIA 2Y0SP 3IU3I 4A3BL 3M4OL 3MPSA 3PKJA 3S1QL 4GS7D 3S15L 5M3ML 1LTLA 1YK4A 2NVYL 3K7AL 5GAGc 2JI2A 1QYBA 1BQ8A 1VZGA 4A93L 1IW7D 2E2IL 3I4NL 2KKDA 3KYVA 4A3IL 4JAFA 4AI2A 5K2ME 4G6BA 1FHMA 1T9QA 2V0EA 1LKMA 3K35A 3H9BA 2NVTL 1IU6A 1NNQA 1BFYA 4AHZA 1K83L 5M5YL 1R0GA 3I4ML 5RXNA 4POFA 1B13A 1QCVA 1PFWA 2PMZP 1R9TL 4AR3A 3HOYL 4YWLA 5IP7L 5H1Sc 4C2M1 1BRFA 2A69D 4POGA 3GTLL 3RYGA 4A3JL 4A3DL 3J7Z1 5IYBL 1T9OA 1YUXA 4LHLA 4B8CD 4AI0A 3PKIA 5MFZA 3HOZL 1H7VA 5GAEc 2E2JL 1CADA 2ERSA 4JAEA 1DVBA 2DSXA 1T9PA 4E6YA 1PFUA 1S30A 1YK5A 3HOUL 3LWQB 3P2AA 3S1RL 1LKOA 3H9CA 4A3EL 2JI3A 2CKCA 1RDGA 4JAGA 1SFOL 5MLC3 4BY1L 1BE7A 3GTML 3S16L 1TWAL 4TVMA 4X6AL 7RXNA 3WWLA 3MQKB 1RWDA 1SMUA 4ZN3B 5IP9L 4A3ML 3LWVB 1B2JA 1SMWA 3S2HL 2JA8L 3QVDA 5C4JL 2XJVA 2ZIXA 1VCXA 3PO2L 4AR5A 2JA7L 1R0IA 2XJRA 1PZXA 1TWCL 2H12A 1C09A 5MGNA 1I3QL 5M5XL 2C6BA 5AN9H 3HOWL 5IYCL 3HOVL 3LWPB 1R0JA 4XGHA 1OWBA 2J9UB 2L0ZA 5C44L 2HVYC 2XJSA 1CAAA 6RXNA 2Z3QB 2ERJA 4V196 3GTQL 4C3JL 1PFYA 3B0AB 4U671 1RDVA 3NFPI 4A3CL 5GAHc 5GADc 3RZDL 1JYBA 3GTKL 2NYDA 4XXBB 3B08B 2A68D 3FKIL 1Y1WL 2XJQA 1WJVA 1B71A 1DX8A 4A3LL 3HJWB 1Z92B 3CQZL 3GTOL 1LKPA 1S24A 1I6HL 4AI3A 5AI3A 4C3HL 2AYJA 2V0FA 2WAQP 3PZAA 4BXXL 1RB9A 2JI1A 3M3YL 2R93L 1SMMA 3LWRB 3H99A 2V3BB 5EINC 5MFPA 3FDJA 2LCQA 2EY4E 5C4XL 2YU9L 8RXNA 2A6HD 5IY0A 1OWCA 1ZRPA 4AHXA 1RYQA 3H3VM 3KYUA 4LHNA 1TWFL 3KYXA 3HJYB 2XJUA 3VPBE 2NVXL 4AR6A 2M6OA 3ZG6A 2BE5D 1BQ9A 4C3IL 1TWHL 1FHHA 1F4LA 2HR5A 2XJTA 3SS2A 5EIOC 3LWOB 2NVQL 2R7ZL 2JA6L 1QQTA 4WFN1 1IRNA 5DM61 3LNLA 2CR8A 3LPEB 3MSUA 3GTJL 2RDVA 4AHYA 4UY81 5DM71 2PSMC 3QQCE 3A44A 4A3FL 2B63L 5AI2A 3KYYA 3S1NL 2CKAA 2C6AA 3HAXC 4K9FA 4BY7L 1Y1VL 3S14L 1E8JA 2A6ED 1R0FA 3HOXL 1I50L 3H0GL 1RYTA 1S2ZA 5JVG1 2RFKB 2Z3RB 2VL6A 3HKZP 1P7PA 1B2OA 2QL0A 5JVH1 2B5ID 1VZHA 5FLML 2VUML 1WCML 4QIWP 3PIO1 5M5WL 5MF6A 3PIP1 4TPUA 2PPTA 4A3KL 3GTPL 4AHWA 4Y7NL 2E2HL 4AYBP 2PVXA 2R92L 2M4YA 4RXNA 2JA5L 3S17L 3S2DL 2KN9A
chains in the Genus database with same CATH topology
2NVXL 4A3GL 1TWCL 1I3QL 4C3IL 5M5XL 1TWHL 2NVTL 3PO3L 3HOWL 5IYCL 1K83L 2NVQL 3HOVL 5M5YL 5M3FL 2R7ZL 2JA6L 3I4ML 3RZOL 2PMZP 1R9TL 5C44L 3HOYL 5IP7L 3GTGL 3GTQL 3GTJL 4C3JL 4C2M1 5FJ8L 3GTLL 4A3JL 4A3CL 4A3FL 3RZDL 2B63L 4A3DL 2WB1P 3GTKL 4BBRL 5IYBL 3S1NL 4BY7L 5IYDL 3FKIL 1Y1VL 3S14L 3S1ML 1Y1WL 1TWGL 3HOZL 4Y52L 2E2JL 4A3LL 3HOUL 3CQZL 3HOXL 3GTOL 4BBSL 5C3EL 1I50L 3H0GL 1I6HL 3S1RL 4C3HL 4A3EL 2WAQP 3HKZP 4BXXL 3M3YL 2Y0SP 1SFOL 4A3BL 2R93L 3M4OL 4BY1L 3S1QL 3S15L 3GTML 3S16L 5FLML 5M3ML 1TWAL 2NVYL 2VUML 4X6AL 1WCML 3K7AL 5C4XL 4QIWP 2YU9L 5M5WL 5IP9L 4A93L 4A3ML 4A3KL 2E2IL 3H3VM 3GTPL 3I4NL 3S2HL 1TWFL 2JA8L 4Y7NL 5C4JL 2E2HL 4AYBP 4A3IL 2R92L 3PO2L 2JA7L 2JA5L 3S17L 3S2DL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NVX L;  4A3G L;  1TWC L;  1I3Q L;  4C3I L;  5M5X L;  1TWH L;  2NVT L;  3PO3 L;  3HOW L;  5IYC L;  1K83 L;  2NVQ L;  3HOV L;  5M5Y L;  5M3F L;  2R7Z L;  2JA6 L;  3I4M L;  3RZO L;  2PMZ P;  1R9T L;  5C44 L;  3HOY L;  5IP7 L;  3GTG L;  3GTQ L;  3GTJ L;  4C3J L;  4C2M 1;  5FJ8 L;  3GTL L;  4A3J L;  4A3C L;  4A3F L;  3RZD L;  2B63 L;  4A3D L;  2WB1 P;  3GTK L;  4BBR L;  5IYB L;  3S1N L;  4BY7 L;  5IYD L;  3FKI L;  1Y1V L;  3S14 L;  3S1M L;  1Y1W L;  1TWG L;  3HOZ L;  4Y52 L;  2E2J L;  4A3L L;  3HOU L;  3CQZ L;  3HOX L;  3GTO L;  4BBS L;  5C3E L;  1I50 L;  3H0G L;  1I6H L;  3S1R L;  4C3H L;  4A3E L;  2WAQ P;  3HKZ P;  4BXX L;  3M3Y L;  2Y0S P;  1SFO L;  4A3B L;  2R93 L;  3M4O L;  4BY1 L;  3S1Q L;  3S15 L;  3GTM L;  3S16 L;  5FLM L;  5M3M L;  1TWA L;  2NVY L;  2VUM L;  4X6A L;  1WCM L;  3K7A L;  5C4X L;  4QIW P;  2YU9 L;  5M5W L;  5IP9 L;  4A93 L;  4A3M L;  4A3K L;  2E2I L;  3H3V M;  3GTP L;  3I4N L;  3S2H L;  1TWF L;  2JA8 L;  4Y7N L;  5C4J L;  2E2H L;  4AYB P;  4A3I L;  2R92 L;  3PO2 L;  2JA7 L;  2JA5 L;  3S17 L;  3S2D L; 
#chains in the Genus database with same CATH topology
 4A3G L;  4YWM A;  1YUZ A;  4AI1 A;  2AQC A;  3WWN B;  3PO3 L;  3JR7 A;  5M3F L;  3RZO L;  2PYA A;  2K2D A;  3P8B A;  2AUS B;  2MS3 A;  3GTG L;  2PVE A;  4AR4 A;  3PL5 A;  3KYW A;  1NXG A;  4JAD A;  5FJ8 L;  1IRO A;  1ODH A;  2WB1 P;  4BBR L;  1IU5 A;  3RZ6 A;  5IYD L;  3S1M L;  1YV1 A;  1TWG L;  2APO B;  2M4V A;  1PFV A;  2M6P A;  4Y52 L;  1R0H A;  2GMG A;  3RZT A;  4BBS L;  5C3E L;  4ME3 A;  4ZN1 B;  3J7Y 1;  2XJP A;  3H97 A;  1NXE A;  3PWF A;  2O5J D;  1VZI A;  2Y0S P;  3IU3 I;  4A3B L;  3M4O L;  3MPS A;  3PKJ A;  3S1Q L;  4GS7 D;  3S15 L;  5M3M L;  1LTL A;  1YK4 A;  2NVY L;  3K7A L;  5GAG c;  2JI2 A;  1QYB A;  1BQ8 A;  1VZG A;  4A93 L;  1IW7 D;  2E2I L;  3I4N L;  2KKD A;  3KYV A;  4A3I L;  4JAF A;  4AI2 A;  5K2M E;  4G6B A;  1FHM A;  1T9Q A;  2V0E A;  1LKM A;  3K35 A;  3H9B A;  2NVT L;  1IU6 A;  1NNQ A;  1BFY A;  4AHZ A;  1K83 L;  5M5Y L;  1R0G A;  3I4M L;  5RXN A;  4POF A;  1B13 A;  1QCV A;  1PFW A;  2PMZ P;  1R9T L;  4AR3 A;  3HOY L;  4YWL A;  5IP7 L;  5H1S c;  4C2M 1;  1BRF A;  2A69 D;  4POG A;  3GTL L;  3RYG A;  4A3J L;  4A3D L;  3J7Z 1;  5IYB L;  1T9O A;  1YUX A;  4LHL A;  4B8C D;  4AI0 A;  3PKI A;  5MFZ A;  3HOZ L;  1H7V A;  5GAE c;  2E2J L;  1CAD A;  2ERS A;  4JAE A;  1DVB A;  2DSX A;  1T9P A;  4E6Y A;  1PFU A;  1S30 A;  1YK5 A;  3HOU L;  3LWQ B;  3P2A A;  3S1R L;  1LKO A;  3H9C A;  4A3E L;  2JI3 A;  2CKC A;  1RDG A;  4JAG A;  1SFO L;  5MLC 3;  4BY1 L;  1BE7 A;  3GTM L;  3S16 L;  1TWA L;  4TVM A;  4X6A L;  7RXN A;  3WWL A;  3MQK B;  1RWD A;  1SMU A;  4ZN3 B;  5IP9 L;  4A3M L;  3LWV B;  1B2J A;  1SMW A;  3S2H L;  2JA8 L;  3QVD A;  5C4J L;  2XJV A;  2ZIX A;  1VCX A;  3PO2 L;  4AR5 A;  2JA7 L;  1R0I A;  2XJR A;  1PZX A;  1TWC L;  2H12 A;  1C09 A;  5MGN A;  1I3Q L;  5M5X L;  2C6B A;  5AN9 H;  3HOW L;  5IYC L;  3HOV L;  3LWP B;  1R0J A;  4XGH A;  1OWB A;  2J9U B;  2L0Z A;  5C44 L;  2HVY C;  2XJS A;  1CAA A;  6RXN A;  2Z3Q B;  2ERJ A;  4V19 6;  3GTQ L;  4C3J L;  1PFY A;  3B0A B;  4U67 1;  1RDV A;  3NFP I;  4A3C L;  5GAH c;  5GAD c;  3RZD L;  1JYB A;  3GTK L;  2NYD A;  4XXB B;  3B08 B;  2A68 D;  3FKI L;  1Y1W L;  2XJQ A;  1WJV A;  1B71 A;  1DX8 A;  4A3L L;  3HJW B;  1Z92 B;  3CQZ L;  3GTO L;  1LKP A;  1S24 A;  1I6H L;  4AI3 A;  5AI3 A;  4C3H L;  2AYJ A;  2V0F A;  2WAQ P;  3PZA A;  4BXX L;  1RB9 A;  2JI1 A;  3M3Y L;  2R93 L;  1SMM A;  3LWR B;  3H99 A;  2V3B B;  5EIN C;  5MFP A;  3FDJ A;  2LCQ A;  2EY4 E;  5C4X L;  2YU9 L;  8RXN A;  2A6H D;  5IY0 A;  1OWC A;  1ZRP A;  4AHX A;  1RYQ A;  3H3V M;  3KYU A;  4LHN A;  1TWF L;  3KYX A;  3HJY B;  2XJU A;  3VPB E;  2NVX L;  4AR6 A;  2M6O A;  3ZG6 A;  2BE5 D;  1BQ9 A;  4C3I L;  1TWH L;  1FHH A;  1F4L A;  2HR5 A;  2XJT A;  3SS2 A;  5EIO C;  3LWO B;  2NVQ L;  2R7Z L;  2JA6 L;  1QQT A;  4WFN 1;  1IRN A;  5DM6 1;  3LNL A;  2CR8 A;  3LPE B;  3MSU A;  3GTJ L;  2RDV A;  4AHY A;  4UY8 1;  5DM7 1;  2PSM C;  3QQC E;  3A44 A;  4A3F L;  2B63 L;  5AI2 A;  3KYY A;  3S1N L;  2CKA A;  2C6A A;  3HAX C;  4K9F A;  4BY7 L;  1Y1V L;  3S14 L;  1E8J A;  2A6E D;  1R0F A;  3HOX L;  1I50 L;  3H0G L;  1RYT A;  1S2Z A;  5JVG 1;  2RFK B;  2Z3R B;  2VL6 A;  3HKZ P;  1P7P A;  1B2O A;  2QL0 A;  5JVH 1;  2B5I D;  1VZH A;  5FLM L;  2VUM L;  1WCM L;  4QIW P;  3PIO 1;  5M5W L;  5MF6 A;  3PIP 1;  4TPU A;  2PPT A;  4A3K L;  3GTP L;  4AHW A;  4Y7N L;  2E2H L;  4AYB P;  2PVX A;  2R92 L;  2M4Y A;  4RXN A;  2JA5 L;  3S17 L;  3S2D L;  2KN9 A; 
#chains in the Genus database with same CATH homology
 2NVX L;  4A3G L;  1TWC L;  1I3Q L;  4C3I L;  5M5X L;  1TWH L;  2NVT L;  3PO3 L;  3HOW L;  5IYC L;  1K83 L;  2NVQ L;  3HOV L;  5M5Y L;  5M3F L;  2R7Z L;  2JA6 L;  3I4M L;  3RZO L;  2PMZ P;  1R9T L;  5C44 L;  3HOY L;  5IP7 L;  3GTG L;  3GTQ L;  3GTJ L;  4C3J L;  4C2M 1;  5FJ8 L;  3GTL L;  4A3J L;  4A3C L;  4A3F L;  3RZD L;  2B63 L;  4A3D L;  2WB1 P;  3GTK L;  4BBR L;  5IYB L;  3S1N L;  4BY7 L;  5IYD L;  3FKI L;  1Y1V L;  3S14 L;  3S1M L;  1Y1W L;  1TWG L;  3HOZ L;  4Y52 L;  2E2J L;  4A3L L;  3HOU L;  3CQZ L;  3HOX L;  3GTO L;  4BBS L;  5C3E L;  1I50 L;  3H0G L;  1I6H L;  3S1R L;  4C3H L;  4A3E L;  2WAQ P;  3HKZ P;  4BXX L;  3M3Y L;  2Y0S P;  1SFO L;  4A3B L;  2R93 L;  3M4O L;  4BY1 L;  3S1Q L;  3S15 L;  3GTM L;  3S16 L;  5FLM L;  5M3M L;  1TWA L;  2NVY L;  2VUM L;  4X6A L;  1WCM L;  3K7A L;  5C4X L;  4QIW P;  2YU9 L;  5M5W L;  5IP9 L;  4A93 L;  4A3M L;  4A3K L;  2E2I L;  3H3V M;  3GTP L;  3I4N L;  3S2H L;  1TWF L;  2JA8 L;  4Y7N L;  5C4J L;  2E2H L;  4AYB P;  4A3I L;  2R92 L;  3PO2 L;  2JA7 L;  2JA5 L;  3S17 L;  3S2D L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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