5IYDL

Human core-pic in the initial transcribing state (no iis)
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
QPMIYICGECHTENEIKSRDPIRCRECGYRIMYKKRTKRLVVFDAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Near-atomic resolution visualization of human transcription promoter opening.
pubmed doi rcsb
molecule tags Transcription, transferase/dna/rna
source organism Homo sapiens
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 1
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2016-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 5iydL00
4X6AL 3M4OL 5C3EL 1TWGL 2NVTL 4A3JL 2JA5L 1TWCL 3S15L 3GTGL 3S1NL 4BY7L 3GTML 4A3IL 5M3FL 5IYBL 2E2IL 1I3QL 4Y7NL 3K7AL 4C3IL 1R9TL 3HOWL 4A3KL 1WCML 5M3ML 2E2JL 5IYCL 3HKZP 5M5YL 3S1ML 3S2HL 5IYDL 3GTPL 5IP7L 5IP9L 4A3DL 3HOZL 4C3HL 1K83L 2JA6L 2B63L 2VUML 1TWFL 4C3JL 2NVQL 3S2DL 4A3GL 4QIWP 3HOUL 3GTKL 3GTQL 3S17L 2PMZP 1TWAL 3RZDL 4Y52L 4A3CL 1TWHL 4BBSL 3FKIL 3H3VM 3HOYL 3PO2L 5C4JL 4A3ML 3CQZL 4A93L 3S1RL 4BXXL 5M5XL 3GTLL 3HOVL 3I4ML 2NVXL 2YU9L 2WAQP 3PO3L 2NVYL 2R7ZL 2Y0SP 4BY1L 1SFOL 3GTOL 3HOXL 2R92L 4BBRL 5M5WL 4A3BL 4C2M1 5FJ8L 3M3YL 3I4NL 3S14L 1I50L 2JA8L 2E2HL 5FLML 4A3LL 1Y1WL 4A3EL 1Y1VL 3GTJL 5C4XL 3S1QL 1I6HL 2WB1P 4AYBP 3RZOL 2JA7L 3H0GL 3S16L 2R93L 5C44L 4A3FL
chains in the Genus database with same CATH superfamily
4A3JL 2HVYC 4G6BA 1Z92B 1F4LA 3J7Y1 1TWCL 4ZN3B 3GTGL 4A3IL 5IYBL 3VPBE 4LHLA 4JAEA 2M4YA 3KYVA 4ME3A 4AR6A 4AI0A 5JVH1 5GADc 3H97A 1OWBA 1PZXA 3PKIA 2E2JL 1H7VA 5IYCL 5M5YL 3S1ML 1VCXA 2AQCA 3GTPL 3PL5A 1FHMA 1FHHA 3FDJA 5DM71 2VUML 4TVMA 4YWLA 3ZG6A 3HJWB 3GTQL 4XGHA 4A3CL 5JVG1 1LTLA 3FKIL 3H3VM 3HOYL 3B08B 2A6ED 1B2OA 1YUZA 3S1RL 2KN9A 5M5XL 3GTLL 3I4ML 2NVXL 2YU9L 2NVYL 2AYJA 3KYYA 2ERSA 4BY1L 2V3BB 4BBRL 4A3BL 4C2M1 2L0ZA 3S14L 1I50L 2E2HL 4A3LL 3GTJL 5C4XL 1QCVA 2XJTA 2APOB 2B5ID 2ERJA 1BFYA 7RXNA 3K35A 3WWLA 4AI3A 2JA5L 2PYAA 4K9FA 2RFKB 4BY7L 2PVXA 1BQ9A 1YK5A 1NNQA 2RDVA 3MPSA 3P8BA 1OWCA 3HOWL 1WCML 2EY4E 2K2DA 2LCQA 1LKMA 4JADA 1BQ8A 4V196 4AR5A 2DSXA 5EINC 3KYXA 5IYDL 3PKJA 3HOZL 5MLC3 4C3JL 3S2DL 2NVQL 4A3GL 2HR5A 4WFN1 4QIWP 3HOUL 1R0IA 1IU6A 1S2ZA 2XJSA 2JI1A 4YWMA 1B13A 2PSMC 3SS2A 5EIOC 1IROA 2PMZP 1TWAL 2V0EA 4Y52L 1YUXA 3MSUA 5RXNA 4BBSL 2JI2A 3J7Z1 4AI1A 5C4JL 3HAXC 1DX8A 5AN9H 4A3ML 5GAHc 1RWDA 4A93L 5IY0A 4UY81 4AHWA 3HOVL 2Z3QB 3LWQB 3PO3L 2Y0SP 5AI3A 3PIP1 3HOXL 5M5WL 2XJQA 5FJ8L 3LWOB 1RDGA 5FLML 1SMUA 3LPEB 4A3EL 1Y1VL 3S1QL 1IW7D 1CAAA 4AYBP 4AHYA 2JA7L 1S30A 2R93L 3RZTA 4A3FL 4POGA 5DM61 1C09A 2JI3A 4X6AL 3M4OL 2XJVA 5H1Sc 2NVTL 1QYBA 2O5JD 1NXEA 4XXBB 3S15L 1S24A 2M6OA 3H99A 4AI2A 1SMWA 2KKDA 3PZAA 4LHNA 3K7AL 4Y7NL 1R9TL 4A3KL 3PWFA 1RYTA 1E8JA 5GAEc 1R0HA 2C6BA 3HJYB 1B2JA 2C6AA 2NYDA 5IP7L 5IP9L 3B0AB 4A3DL 5MFPA 3JR7A 4C3HL 1K83L 1ZRPA 1BRFA 1TWFL 1JYBA 2BE5D 3GTKL 2QL0A 2J9UB 3RYGA 3S17L 1VZHA 3RZDL 2MS3A 2H12A 2M4VA 2V0FA 4JAFA 5K2ME 6RXNA 5MF6A 1QQTA 1R0JA 3PO2L 4JAGA 1T9PA 3WWNB 3MQKB 2M6PA 4BXXL 1PFWA 4E6YA 3LWPB 2WAQP 2R7ZL 1RDVA 1SFOL 3GTOL 4TPUA 2Z3RB 2R92L 2CR8A 2XJPA 3I4NL 1DVBA 3LNLA 8RXNA 2JA8L 1T9OA 3IU3I 5MGNA 1IRNA 1VZGA 4ZN1B 3QVDA 1IU5A 2PVEA 3A44A 5C3EL 1BE7A 1TWGL 2CKCA 2XJRA 1R0FA 2PPTA 3S1NL 1NXGA 3GTML 5M3FL 3NFPI 4RXNA 3H9BA 2E2IL 1LKOA 1I3QL 2A69D 1YK4A 4C3IL 1YV1A 1PFYA 1CADA 1R0GA 1VZIA 3PIO1 5M3ML 1RYQA 2CKAA 1ODHA 3HKZP 1WJVA 3S2HL 2A6HD 1PFVA 3LWRB 4AHXA 2JA6L 1LKPA 2B63L 2A68D 3QQCE 2AUSB 4U671 4AHZA 5MFZA 2GMGA 1P7PA 1TWHL 4AR3A 1RB9A 4POFA 1B71A 3CQZL 3KYUA 1SMMA 1PFUA 5AI2A 5GAGc 4B8CD 2ZIXA 3LWVB 4GS7D 2VL6A 3M3YL 1T9QA 3RZ6A 3H9CA 1Y1WL 3P2AA 2XJUA 3KYWA 1I6HL 2WB1P 3RZOL 3H0GL 4AR4A 3S16L 5C44L
chains in the Genus database with same CATH topology
4X6AL 3M4OL 5C3EL 1TWGL 2NVTL 4A3JL 2JA5L 1TWCL 3S15L 3GTGL 3S1NL 4BY7L 3GTML 4A3IL 5M3FL 5IYBL 2E2IL 1I3QL 4Y7NL 3K7AL 4C3IL 1R9TL 3HOWL 4A3KL 1WCML 5M3ML 2E2JL 5IYCL 3HKZP 5M5YL 3S1ML 3S2HL 5IYDL 3GTPL 5IP7L 5IP9L 4A3DL 3HOZL 4C3HL 1K83L 2JA6L 2B63L 2VUML 1TWFL 4C3JL 2NVQL 3S2DL 4A3GL 4QIWP 3HOUL 3GTKL 3GTQL 3S17L 2PMZP 1TWAL 3RZDL 4Y52L 4A3CL 1TWHL 4BBSL 3FKIL 3H3VM 3HOYL 3PO2L 5C4JL 4A3ML 3CQZL 4A93L 3S1RL 4BXXL 5M5XL 3GTLL 3HOVL 3I4ML 2NVXL 2YU9L 2WAQP 3PO3L 2NVYL 2R7ZL 2Y0SP 4BY1L 1SFOL 3GTOL 3HOXL 2R92L 4BBRL 5M5WL 4A3BL 4C2M1 5FJ8L 3M3YL 3I4NL 3S14L 1I50L 2JA8L 2E2HL 5FLML 4A3LL 1Y1WL 4A3EL 1Y1VL 3GTJL 5C4XL 3S1QL 1I6HL 2WB1P 4AYBP 3RZOL 2JA7L 3H0GL 3S16L 2R93L 5C44L 4A3FL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4X6A L;  3M4O L;  5C3E L;  1TWG L;  2NVT L;  4A3J L;  2JA5 L;  1TWC L;  3S15 L;  3GTG L;  3S1N L;  4BY7 L;  3GTM L;  4A3I L;  5M3F L;  5IYB L;  2E2I L;  1I3Q L;  4Y7N L;  3K7A L;  4C3I L;  1R9T L;  3HOW L;  4A3K L;  1WCM L;  5M3M L;  2E2J L;  5IYC L;  3HKZ P;  5M5Y L;  3S1M L;  3S2H L;  5IYD L;  3GTP L;  5IP7 L;  5IP9 L;  4A3D L;  3HOZ L;  4C3H L;  1K83 L;  2JA6 L;  2B63 L;  2VUM L;  1TWF L;  4C3J L;  2NVQ L;  3S2D L;  4A3G L;  4QIW P;  3HOU L;  3GTK L;  3GTQ L;  3S17 L;  2PMZ P;  1TWA L;  3RZD L;  4Y52 L;  4A3C L;  1TWH L;  4BBS L;  3FKI L;  3H3V M;  3HOY L;  3PO2 L;  5C4J L;  4A3M L;  3CQZ L;  4A93 L;  3S1R L;  4BXX L;  5M5X L;  3GTL L;  3HOV L;  3I4M L;  2NVX L;  2YU9 L;  2WAQ P;  3PO3 L;  2NVY L;  2R7Z L;  2Y0S P;  4BY1 L;  1SFO L;  3GTO L;  3HOX L;  2R92 L;  4BBR L;  5M5W L;  4A3B L;  4C2M 1;  5FJ8 L;  3M3Y L;  3I4N L;  3S14 L;  1I50 L;  2JA8 L;  2E2H L;  5FLM L;  4A3L L;  1Y1W L;  4A3E L;  1Y1V L;  3GTJ L;  5C4X L;  3S1Q L;  1I6H L;  2WB1 P;  4AYB P;  3RZO L;  2JA7 L;  3H0G L;  3S16 L;  2R93 L;  5C44 L;  4A3F L; 
#chains in the Genus database with same CATH topology
 4A3J L;  2HVY C;  4G6B A;  1Z92 B;  1F4L A;  3J7Y 1;  1TWC L;  4ZN3 B;  3GTG L;  4A3I L;  5IYB L;  3VPB E;  4LHL A;  4JAE A;  2M4Y A;  3KYV A;  4ME3 A;  4AR6 A;  4AI0 A;  5JVH 1;  5GAD c;  3H97 A;  1OWB A;  1PZX A;  3PKI A;  2E2J L;  1H7V A;  5IYC L;  5M5Y L;  3S1M L;  1VCX A;  2AQC A;  3GTP L;  3PL5 A;  1FHM A;  1FHH A;  3FDJ A;  5DM7 1;  2VUM L;  4TVM A;  4YWL A;  3ZG6 A;  3HJW B;  3GTQ L;  4XGH A;  4A3C L;  5JVG 1;  1LTL A;  3FKI L;  3H3V M;  3HOY L;  3B08 B;  2A6E D;  1B2O A;  1YUZ A;  3S1R L;  2KN9 A;  5M5X L;  3GTL L;  3I4M L;  2NVX L;  2YU9 L;  2NVY L;  2AYJ A;  3KYY A;  2ERS A;  4BY1 L;  2V3B B;  4BBR L;  4A3B L;  4C2M 1;  2L0Z A;  3S14 L;  1I50 L;  2E2H L;  4A3L L;  3GTJ L;  5C4X L;  1QCV A;  2XJT A;  2APO B;  2B5I D;  2ERJ A;  1BFY A;  7RXN A;  3K35 A;  3WWL A;  4AI3 A;  2JA5 L;  2PYA A;  4K9F A;  2RFK B;  4BY7 L;  2PVX A;  1BQ9 A;  1YK5 A;  1NNQ A;  2RDV A;  3MPS A;  3P8B A;  1OWC A;  3HOW L;  1WCM L;  2EY4 E;  2K2D A;  2LCQ A;  1LKM A;  4JAD A;  1BQ8 A;  4V19 6;  4AR5 A;  2DSX A;  5EIN C;  3KYX A;  5IYD L;  3PKJ A;  3HOZ L;  5MLC 3;  4C3J L;  3S2D L;  2NVQ L;  4A3G L;  2HR5 A;  4WFN 1;  4QIW P;  3HOU L;  1R0I A;  1IU6 A;  1S2Z A;  2XJS A;  2JI1 A;  4YWM A;  1B13 A;  2PSM C;  3SS2 A;  5EIO C;  1IRO A;  2PMZ P;  1TWA L;  2V0E A;  4Y52 L;  1YUX A;  3MSU A;  5RXN A;  4BBS L;  2JI2 A;  3J7Z 1;  4AI1 A;  5C4J L;  3HAX C;  1DX8 A;  5AN9 H;  4A3M L;  5GAH c;  1RWD A;  4A93 L;  5IY0 A;  4UY8 1;  4AHW A;  3HOV L;  2Z3Q B;  3LWQ B;  3PO3 L;  2Y0S P;  5AI3 A;  3PIP 1;  3HOX L;  5M5W L;  2XJQ A;  5FJ8 L;  3LWO B;  1RDG A;  5FLM L;  1SMU A;  3LPE B;  4A3E L;  1Y1V L;  3S1Q L;  1IW7 D;  1CAA A;  4AYB P;  4AHY A;  2JA7 L;  1S30 A;  2R93 L;  3RZT A;  4A3F L;  4POG A;  5DM6 1;  1C09 A;  2JI3 A;  4X6A L;  3M4O L;  2XJV A;  5H1S c;  2NVT L;  1QYB A;  2O5J D;  1NXE A;  4XXB B;  3S15 L;  1S24 A;  2M6O A;  3H99 A;  4AI2 A;  1SMW A;  2KKD A;  3PZA A;  4LHN A;  3K7A L;  4Y7N L;  1R9T L;  4A3K L;  3PWF A;  1RYT A;  1E8J A;  5GAE c;  1R0H A;  2C6B A;  3HJY B;  1B2J A;  2C6A A;  2NYD A;  5IP7 L;  5IP9 L;  3B0A B;  4A3D L;  5MFP A;  3JR7 A;  4C3H L;  1K83 L;  1ZRP A;  1BRF A;  1TWF L;  1JYB A;  2BE5 D;  3GTK L;  2QL0 A;  2J9U B;  3RYG A;  3S17 L;  1VZH A;  3RZD L;  2MS3 A;  2H12 A;  2M4V A;  2V0F A;  4JAF A;  5K2M E;  6RXN A;  5MF6 A;  1QQT A;  1R0J A;  3PO2 L;  4JAG A;  1T9P A;  3WWN B;  3MQK B;  2M6P A;  4BXX L;  1PFW A;  4E6Y A;  3LWP B;  2WAQ P;  2R7Z L;  1RDV A;  1SFO L;  3GTO L;  4TPU A;  2Z3R B;  2R92 L;  2CR8 A;  2XJP A;  3I4N L;  1DVB A;  3LNL A;  8RXN A;  2JA8 L;  1T9O A;  3IU3 I;  5MGN A;  1IRN A;  1VZG A;  4ZN1 B;  3QVD A;  1IU5 A;  2PVE A;  3A44 A;  5C3E L;  1BE7 A;  1TWG L;  2CKC A;  2XJR A;  1R0F A;  2PPT A;  3S1N L;  1NXG A;  3GTM L;  5M3F L;  3NFP I;  4RXN A;  3H9B A;  2E2I L;  1LKO A;  1I3Q L;  2A69 D;  1YK4 A;  4C3I L;  1YV1 A;  1PFY A;  1CAD A;  1R0G A;  1VZI A;  3PIO 1;  5M3M L;  1RYQ A;  2CKA A;  1ODH A;  3HKZ P;  1WJV A;  3S2H L;  2A6H D;  1PFV A;  3LWR B;  4AHX A;  2JA6 L;  1LKP A;  2B63 L;  2A68 D;  3QQC E;  2AUS B;  4U67 1;  4AHZ A;  5MFZ A;  2GMG A;  1P7P A;  1TWH L;  4AR3 A;  1RB9 A;  4POF A;  1B71 A;  3CQZ L;  3KYU A;  1SMM A;  1PFU A;  5AI2 A;  5GAG c;  4B8C D;  2ZIX A;  3LWV B;  4GS7 D;  2VL6 A;  3M3Y L;  1T9Q A;  3RZ6 A;  3H9C A;  1Y1W L;  3P2A A;  2XJU A;  3KYW A;  1I6H L;  2WB1 P;  3RZO L;  3H0G L;  4AR4 A;  3S16 L;  5C44 L; 
#chains in the Genus database with same CATH homology
 4X6A L;  3M4O L;  5C3E L;  1TWG L;  2NVT L;  4A3J L;  2JA5 L;  1TWC L;  3S15 L;  3GTG L;  3S1N L;  4BY7 L;  3GTM L;  4A3I L;  5M3F L;  5IYB L;  2E2I L;  1I3Q L;  4Y7N L;  3K7A L;  4C3I L;  1R9T L;  3HOW L;  4A3K L;  1WCM L;  5M3M L;  2E2J L;  5IYC L;  3HKZ P;  5M5Y L;  3S1M L;  3S2H L;  5IYD L;  3GTP L;  5IP7 L;  5IP9 L;  4A3D L;  3HOZ L;  4C3H L;  1K83 L;  2JA6 L;  2B63 L;  2VUM L;  1TWF L;  4C3J L;  2NVQ L;  3S2D L;  4A3G L;  4QIW P;  3HOU L;  3GTK L;  3GTQ L;  3S17 L;  2PMZ P;  1TWA L;  3RZD L;  4Y52 L;  4A3C L;  1TWH L;  4BBS L;  3FKI L;  3H3V M;  3HOY L;  3PO2 L;  5C4J L;  4A3M L;  3CQZ L;  4A93 L;  3S1R L;  4BXX L;  5M5X L;  3GTL L;  3HOV L;  3I4M L;  2NVX L;  2YU9 L;  2WAQ P;  3PO3 L;  2NVY L;  2R7Z L;  2Y0S P;  4BY1 L;  1SFO L;  3GTO L;  3HOX L;  2R92 L;  4BBR L;  5M5W L;  4A3B L;  4C2M 1;  5FJ8 L;  3M3Y L;  3I4N L;  3S14 L;  1I50 L;  2JA8 L;  2E2H L;  5FLM L;  4A3L L;  1Y1W L;  4A3E L;  1Y1V L;  3GTJ L;  5C4X L;  3S1Q L;  1I6H L;  2WB1 P;  4AYB P;  3RZO L;  2JA7 L;  3H0G L;  3S16 L;  2R93 L;  5C44 L;  4A3F L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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