5J28A

Ki67-pp1g (protein phosphatase 1, gamma isoform) holoenzyme complex
Total Genus 106
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
106
sequence length
293
structure length
293
Chain Sequence
LNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Ki-67 and RepoMan mitotic phosphatases assemble via an identical, yet novel mechanism.
pubmed doi rcsb
molecule tags Hydrolase/protein binding
source organism Homo sapiens
molecule keywords Serine/threonine-protein phosphatase PP1-gamma catalytic sub
total genus 106
structure length 293
sequence length 293
chains with identical sequence B
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2016-03-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
A PF16891 STPPase_N Serine-threonine protein phosphatase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 5j28A00
2BDXA 2WDDA 4UT2A 1HO5A 5EQVA 5INBA 4V0XA 1S70A 3E7AA 1HPUA 5JJTA 1II7A 4O4KA 2WDEA 2Z1AA 1UF3A 3IVDA 4F0ZA 1UTEA 4KBPA 4XPNA 2XMOA 3H69A 2CV9A 3DW8C 1XM7A 4G9JA 4IL1A 4Q7FA 4UWQA 3V4YA 3ZU0A 3QFMA 2IE3C 2NXFA 2QJCA 3QFKA 3AV0A 3DSDA 1M63A 1S3LA 3C9FA 1AUIA 3IB8A 4LACC 1Z2WA 5C1VA 1QHWA 3N5UA 3H66A 5JPFA 1WAO1 4YKEA 5HPEA 4DT2A 3AUZA 2Q8UA 1S95A 1IT6A 5DNYA 1USHA 3QG5C 4JA7A 4H1SA 5JPEA 2IAEC 3T1IA 3H61A 3QFNA 4FBKA 4B2OA 4V0VA 1S8EA 3E7BA 2WDFA 2WDCA 3DSCA 2Z06A 4H1YP 1G5BA 1SU1A 2QFPA 3FGAC 3H67A 4I5NC 4M0VA 3RL5A 3K7WC 3TGHA 3H60A 4DSYA 3P71C 4IYPC 5GTUA 2R17A 4JA9A 2NYLC 4ORBA 3H62B 1S3MA 4ORAA 4DHLA 2NYMC 2A22A 3GVEA 3ICFA 1KBPA 5IOHA 1S3NA 2O8GA 3H63A 1T70A 4MOVA 4O5GA 4LU9A 4TUIA 5F3WA 4O43A 2HYOA 1WARA 3HVQA 4FCXA 2GJUA 4J6OA 2DFJA 5B8IA 2JOGA 3C5WC 4ZVZA 3PSNA 4I5LC 2BQ8X 3K7VC 3IVEA 3THNA 2Z72A 2P6BA 4MOYA 1T71A 2ZBMA 1XZWA 3H68A 4H2FA 4FBWA 4H2GA 2NPPC 2IE4C 3ZTVA 2USHA 1U32A 4HD0A 4TUGA 4MP0A 4UT3B 4LTYA 2QFRA 2KKNA 1OIDA 3THOB 1W24A 4OR9A 4ZX2A 3IB7A 3QFOA 2HY1A 2YVTA 3KBPA 2HYPA 4H2IA 1OI8A 3RL3A 3CK2A 3RQZA 4FBQA 4V0WA 1HP1A 1QFCA 1TCOA 3JYFA 1V73A 3RL4A 4KKZA 2O8AA 4H2BA 3LL8A 1NNWA 2AHDA 4NZVA 5J28A 4UT3A 1Z2XA 2BCDA 1MF8A 4WWLA 3PSOA 1FJMA 4ORCA 1JK7A 3H64A 1OIEA 3EGHA 3EGGA 4O24A
chains in the Genus database with same CATH superfamily
2BDXA 2WDDA 4UT2A 1HO5A 5EQVA 5INBA 3FLOA 1S70A 3E7AA 4V0XA 1HPUA 5JJTA 1II7A 4O4KA 2YEQA 2WDEA 2Z1AA 1UF3A 3IVDA 4F0ZA 1UTEA 4KBPA 4XPNA 2XMOA 3H69A 2CV9A 3DW8C 1XM7A 4G9JA 4IL1A 4Q7FA 4UWQA 3V4YA 3ZU0A 3QFMA 2DXNA 2IE3C 2NXFA 2QJCA 3QFKA 3AV0A 3DSDA 1M63A 1S3LA 3C9FA 1AUIA 3IB8A 4LACC 1Z2WA 5C1VA 1QHWA 3N5UA 3H66A 5JPFA 1WAO1 4YKEA 5HPEA 4DT2A 3AUZA 2Q8UA 1S95A 1IT6A 5DNYA 1USHA 3QG5C 4JA7A 4H1SA 5JPEA 2IAEC 3T1IA 3H61A 3QFNA 4FBKA 4B2OA 4V0VA 1S8EA 2ZO9B 3E7BA 2WDFA 2WDCA 3DSCA 2Z06A 4H1YP 1G5BA 1SU1A 2QFPA 3FGAC 3H67A 4I5NC 4M0VA 3RL5A 3K7WC 3TGHA 3H60A 4DSYA 3P71C 4IYPC 5GTUA 2R17A 4JA9A 2NYLC 4ORBA 3H62B 1S3MA 4ORAA 4DHLA 2NYMC 2A22A 3GVEA 3ICFA 1KBPA 5IOHA 1S3NA 2O8GA 3D03A 3H63A 1T70A 4MOVA 4O5GA 4LU9A 4TUIA 5F3WA 4O43A 2HYOA 3E0JA 1WARA 3HVQA 4FCXA 2GJUA 4J6OA 2DFJA 5B8IA 2JOGA 3C5WC 4ZVZA 3PSNA 4I5LC 2BQ8X 3K7VC 3IVEA 3THNA 2Z72A 2P6BA 4MOYA 1T71A 2ZBMA 1XZWA 3H68A 4H2FA 4FBWA 4H2GA 2NPPC 2IE4C 3ZTVA 2USHA 1U32A 4HD0A 4TUGA 4MP0A 4UT3B 4LTYA 2ZOAA 2QFRA 2KKNA 1OIDA 3THOB 1W24A 4OR9A 4ZX2A 3IB7A 3QFOA 2HY1A 2YVTA 3KBPA 2HYPA 4H2IA 1OI8A 3RL3A 3CK2A 3RQZA 4FBQA 4V0WA 1HP1A 2DXLA 1QFCA 1TCOA 3JYFA 1V73A 3RL4A 4KKZA 2O8AA 4H2BA 3LL8A 1NNWA 2AHDA 4NZVA 5J28A 4UT3A 1Z2XA 2BCDA 1MF8A 4WWLA 3PSOA 1FJMA 4ORCA 1JK7A 3H64A 1OIEA 3EGHA 3EGGA 4O24A
chains in the Genus database with same CATH topology
2BDXA 2WDDA 4UT2A 1HO5A 5EQVA 5INBA 3FLOA 1S70A 3E7AA 4V0XA 1HPUA 5JJTA 1II7A 4O4KA 2YEQA 2WDEA 2Z1AA 1UF3A 3IVDA 4F0ZA 1UTEA 4KBPA 4XPNA 2XMOA 3H69A 2CV9A 3DW8C 1XM7A 4G9JA 4IL1A 4Q7FA 4UWQA 3V4YA 3ZU0A 3QFMA 2DXNA 2IE3C 2NXFA 2QJCA 3QFKA 3AV0A 3DSDA 1M63A 1S3LA 3C9FA 1AUIA 3IB8A 4LACC 1Z2WA 5C1VA 1QHWA 3N5UA 3H66A 5JPFA 1WAO1 4YKEA 5HPEA 4DT2A 3AUZA 2Q8UA 1S95A 1IT6A 5DNYA 1USHA 3QG5C 4JA7A 4H1SA 5JPEA 2IAEC 3T1IA 3H61A 3QFNA 4FBKA 4B2OA 4V0VA 1S8EA 2ZO9B 3E7BA 2WDFA 2WDCA 3DSCA 2Z06A 4H1YP 1G5BA 1SU1A 2QFPA 3FGAC 3H67A 4I5NC 4M0VA 3RL5A 3K7WC 3TGHA 3H60A 4DSYA 3P71C 4IYPC 5GTUA 2R17A 4JA9A 2NYLC 4ORBA 3H62B 1S3MA 4ORAA 4DHLA 2NYMC 2A22A 3GVEA 3ICFA 1KBPA 5IOHA 1S3NA 2O8GA 3D03A 3H63A 1T70A 4MOVA 4O5GA 4LU9A 4TUIA 5F3WA 4O43A 2HYOA 3E0JA 1WARA 3HVQA 4FCXA 2GJUA 4J6OA 2DFJA 5B8IA 2JOGA 3C5WC 4ZVZA 3PSNA 4I5LC 2BQ8X 3K7VC 3IVEA 3THNA 2Z72A 2P6BA 4MOYA 1T71A 2ZBMA 1XZWA 3H68A 4H2FA 4FBWA 4H2GA 2NPPC 2IE4C 3ZTVA 2USHA 1U32A 4HD0A 4TUGA 4MP0A 4UT3B 4LTYA 2ZOAA 2QFRA 2KKNA 1OIDA 3THOB 1W24A 4OR9A 4ZX2A 3IB7A 3QFOA 2HY1A 2YVTA 3KBPA 2HYPA 4H2IA 1OI8A 3RL3A 3CK2A 3RQZA 4FBQA 4V0WA 1HP1A 2DXLA 1QFCA 1TCOA 3JYFA 1V73A 3RL4A 4KKZA 2O8AA 4H2BA 3LL8A 1NNWA 2AHDA 4NZVA 5J28A 4UT3A 1Z2XA 2BCDA 1MF8A 4WWLA 3PSOA 1FJMA 4ORCA 1JK7A 3H64A 1OIEA 3EGHA 3EGGA 4O24A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BDX A;  2WDD A;  4UT2 A;  1HO5 A;  5EQV A;  5INB A;  4V0X A;  1S70 A;  3E7A A;  1HPU A;  5JJT A;  1II7 A;  4O4K A;  2WDE A;  2Z1A A;  1UF3 A;  3IVD A;  4F0Z A;  1UTE A;  4KBP A;  4XPN A;  2XMO A;  3H69 A;  2CV9 A;  3DW8 C;  1XM7 A;  4G9J A;  4IL1 A;  4Q7F A;  4UWQ A;  3V4Y A;  3ZU0 A;  3QFM A;  2IE3 C;  2NXF A;  2QJC A;  3QFK A;  3AV0 A;  3DSD A;  1M63 A;  1S3L A;  3C9F A;  1AUI A;  3IB8 A;  4LAC C;  1Z2W A;  5C1V A;  1QHW A;  3N5U A;  3H66 A;  5JPF A;  1WAO 1;  4YKE A;  5HPE A;  4DT2 A;  3AUZ A;  2Q8U A;  1S95 A;  1IT6 A;  5DNY A;  1USH A;  3QG5 C;  4JA7 A;  4H1S A;  5JPE A;  2IAE C;  3T1I A;  3H61 A;  3QFN A;  4FBK A;  4B2O A;  4V0V A;  1S8E A;  3E7B A;  2WDF A;  2WDC A;  3DSC A;  2Z06 A;  4H1Y P;  1G5B A;  1SU1 A;  2QFP A;  3FGA C;  3H67 A;  4I5N C;  4M0V A;  3RL5 A;  3K7W C;  3TGH A;  3H60 A;  4DSY A;  3P71 C;  4IYP C;  5GTU A;  2R17 A;  4JA9 A;  2NYL C;  4ORB A;  3H62 B;  1S3M A;  4ORA A;  4DHL A;  2NYM C;  2A22 A;  3GVE A;  3ICF A;  1KBP A;  5IOH A;  1S3N A;  2O8G A;  3H63 A;  1T70 A;  4MOV A;  4O5G A;  4LU9 A;  4TUI A;  5F3W A;  4O43 A;  2HYO A;  1WAR A;  3HVQ A;  4FCX A;  2GJU A;  4J6O A;  2DFJ A;  5B8I A;  2JOG A;  3C5W C;  4ZVZ A;  3PSN A;  4I5L C;  2BQ8 X;  3K7V C;  3IVE A;  3THN A;  2Z72 A;  2P6B A;  4MOY A;  1T71 A;  2ZBM A;  1XZW A;  3H68 A;  4H2F A;  4FBW A;  4H2G A;  2NPP C;  2IE4 C;  3ZTV A;  2USH A;  1U32 A;  4HD0 A;  4TUG A;  4MP0 A;  4UT3 B;  4LTY A;  2QFR A;  2KKN A;  1OID A;  3THO B;  1W24 A;  4OR9 A;  4ZX2 A;  3IB7 A;  3QFO A;  2HY1 A;  2YVT A;  3KBP A;  2HYP A;  4H2I A;  1OI8 A;  3RL3 A;  3CK2 A;  3RQZ A;  4FBQ A;  4V0W A;  1HP1 A;  1QFC A;  1TCO A;  3JYF A;  1V73 A;  3RL4 A;  4KKZ A;  2O8A A;  4H2B A;  3LL8 A;  1NNW A;  2AHD A;  4NZV A;  5J28 A;  4UT3 A;  1Z2X A;  2BCD A;  1MF8 A;  4WWL A;  3PSO A;  1FJM A;  4ORC A;  1JK7 A;  3H64 A;  1OIE A;  3EGH A;  3EGG A;  4O24 A; 
#chains in the Genus database with same CATH topology
 2BDX A;  2WDD A;  4UT2 A;  1HO5 A;  5EQV A;  5INB A;  3FLO A;  1S70 A;  3E7A A;  4V0X A;  1HPU A;  5JJT A;  1II7 A;  4O4K A;  2YEQ A;  2WDE A;  2Z1A A;  1UF3 A;  3IVD A;  4F0Z A;  1UTE A;  4KBP A;  4XPN A;  2XMO A;  3H69 A;  2CV9 A;  3DW8 C;  1XM7 A;  4G9J A;  4IL1 A;  4Q7F A;  4UWQ A;  3V4Y A;  3ZU0 A;  3QFM A;  2DXN A;  2IE3 C;  2NXF A;  2QJC A;  3QFK A;  3AV0 A;  3DSD A;  1M63 A;  1S3L A;  3C9F A;  1AUI A;  3IB8 A;  4LAC C;  1Z2W A;  5C1V A;  1QHW A;  3N5U A;  3H66 A;  5JPF A;  1WAO 1;  4YKE A;  5HPE A;  4DT2 A;  3AUZ A;  2Q8U A;  1S95 A;  1IT6 A;  5DNY A;  1USH A;  3QG5 C;  4JA7 A;  4H1S A;  5JPE A;  2IAE C;  3T1I A;  3H61 A;  3QFN A;  4FBK A;  4B2O A;  4V0V A;  1S8E A;  2ZO9 B;  3E7B A;  2WDF A;  2WDC A;  3DSC A;  2Z06 A;  4H1Y P;  1G5B A;  1SU1 A;  2QFP A;  3FGA C;  3H67 A;  4I5N C;  4M0V A;  3RL5 A;  3K7W C;  3TGH A;  3H60 A;  4DSY A;  3P71 C;  4IYP C;  5GTU A;  2R17 A;  4JA9 A;  2NYL C;  4ORB A;  3H62 B;  1S3M A;  4ORA A;  4DHL A;  2NYM C;  2A22 A;  3GVE A;  3ICF A;  1KBP A;  5IOH A;  1S3N A;  2O8G A;  3D03 A;  3H63 A;  1T70 A;  4MOV A;  4O5G A;  4LU9 A;  4TUI A;  5F3W A;  4O43 A;  2HYO A;  3E0J A;  1WAR A;  3HVQ A;  4FCX A;  2GJU A;  4J6O A;  2DFJ A;  5B8I A;  2JOG A;  3C5W C;  4ZVZ A;  3PSN A;  4I5L C;  2BQ8 X;  3K7V C;  3IVE A;  3THN A;  2Z72 A;  2P6B A;  4MOY A;  1T71 A;  2ZBM A;  1XZW A;  3H68 A;  4H2F A;  4FBW A;  4H2G A;  2NPP C;  2IE4 C;  3ZTV A;  2USH A;  1U32 A;  4HD0 A;  4TUG A;  4MP0 A;  4UT3 B;  4LTY A;  2ZOA A;  2QFR A;  2KKN A;  1OID A;  3THO B;  1W24 A;  4OR9 A;  4ZX2 A;  3IB7 A;  3QFO A;  2HY1 A;  2YVT A;  3KBP A;  2HYP A;  4H2I A;  1OI8 A;  3RL3 A;  3CK2 A;  3RQZ A;  4FBQ A;  4V0W A;  1HP1 A;  2DXL A;  1QFC A;  1TCO A;  3JYF A;  1V73 A;  3RL4 A;  4KKZ A;  2O8A A;  4H2B A;  3LL8 A;  1NNW A;  2AHD A;  4NZV A;  5J28 A;  4UT3 A;  1Z2X A;  2BCD A;  1MF8 A;  4WWL A;  3PSO A;  1FJM A;  4ORC A;  1JK7 A;  3H64 A;  1OIE A;  3EGH A;  3EGG A;  4O24 A; 
#chains in the Genus database with same CATH homology
 2BDX A;  2WDD A;  4UT2 A;  1HO5 A;  5EQV A;  5INB A;  3FLO A;  1S70 A;  3E7A A;  4V0X A;  1HPU A;  5JJT A;  1II7 A;  4O4K A;  2YEQ A;  2WDE A;  2Z1A A;  1UF3 A;  3IVD A;  4F0Z A;  1UTE A;  4KBP A;  4XPN A;  2XMO A;  3H69 A;  2CV9 A;  3DW8 C;  1XM7 A;  4G9J A;  4IL1 A;  4Q7F A;  4UWQ A;  3V4Y A;  3ZU0 A;  3QFM A;  2DXN A;  2IE3 C;  2NXF A;  2QJC A;  3QFK A;  3AV0 A;  3DSD A;  1M63 A;  1S3L A;  3C9F A;  1AUI A;  3IB8 A;  4LAC C;  1Z2W A;  5C1V A;  1QHW A;  3N5U A;  3H66 A;  5JPF A;  1WAO 1;  4YKE A;  5HPE A;  4DT2 A;  3AUZ A;  2Q8U A;  1S95 A;  1IT6 A;  5DNY A;  1USH A;  3QG5 C;  4JA7 A;  4H1S A;  5JPE A;  2IAE C;  3T1I A;  3H61 A;  3QFN A;  4FBK A;  4B2O A;  4V0V A;  1S8E A;  2ZO9 B;  3E7B A;  2WDF A;  2WDC A;  3DSC A;  2Z06 A;  4H1Y P;  1G5B A;  1SU1 A;  2QFP A;  3FGA C;  3H67 A;  4I5N C;  4M0V A;  3RL5 A;  3K7W C;  3TGH A;  3H60 A;  4DSY A;  3P71 C;  4IYP C;  5GTU A;  2R17 A;  4JA9 A;  2NYL C;  4ORB A;  3H62 B;  1S3M A;  4ORA A;  4DHL A;  2NYM C;  2A22 A;  3GVE A;  3ICF A;  1KBP A;  5IOH A;  1S3N A;  2O8G A;  3D03 A;  3H63 A;  1T70 A;  4MOV A;  4O5G A;  4LU9 A;  4TUI A;  5F3W A;  4O43 A;  2HYO A;  3E0J A;  1WAR A;  3HVQ A;  4FCX A;  2GJU A;  4J6O A;  2DFJ A;  5B8I A;  2JOG A;  3C5W C;  4ZVZ A;  3PSN A;  4I5L C;  2BQ8 X;  3K7V C;  3IVE A;  3THN A;  2Z72 A;  2P6B A;  4MOY A;  1T71 A;  2ZBM A;  1XZW A;  3H68 A;  4H2F A;  4FBW A;  4H2G A;  2NPP C;  2IE4 C;  3ZTV A;  2USH A;  1U32 A;  4HD0 A;  4TUG A;  4MP0 A;  4UT3 B;  4LTY A;  2ZOA A;  2QFR A;  2KKN A;  1OID A;  3THO B;  1W24 A;  4OR9 A;  4ZX2 A;  3IB7 A;  3QFO A;  2HY1 A;  2YVT A;  3KBP A;  2HYP A;  4H2I A;  1OI8 A;  3RL3 A;  3CK2 A;  3RQZ A;  4FBQ A;  4V0W A;  1HP1 A;  2DXL A;  1QFC A;  1TCO A;  3JYF A;  1V73 A;  3RL4 A;  4KKZ A;  2O8A A;  4H2B A;  3LL8 A;  1NNW A;  2AHD A;  4NZV A;  5J28 A;  4UT3 A;  1Z2X A;  2BCD A;  1MF8 A;  4WWL A;  3PSO A;  1FJM A;  4ORC A;  1JK7 A;  3H64 A;  1OIE A;  3EGH A;  3EGG A;  4O24 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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