5JVH1

The crystal structure large ribosomal subunit (50s) of deinococcus radiodurans in complex with evernimicin
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
53
structure length
53
Chain Sequence
AKDGPRIIVKMESSAGTGFYYTTTKNRRNTQAKLELKKYDPVAKKHVVFREKK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Avilamycin and evernimicin induce structural changes in rProteins uL16 and CTC that enhance the inhibition of A-site tRNA binding.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S ribosomal RNA
total genus 3
structure length 53
sequence length 53
ec nomenclature
pdb deposition date 2016-05-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
1 PF00471 Ribosomal_L33 Ribosomal protein L33
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.120 Mainly Beta Single Sheet Rubrerythrin, domain 2 Rubrerythrin, domain 2 5jvh100
4WFN1 3J7Y1 5DM61 3PIP1 5JVG1 5MLC3 3J7Z1 5GADc 5JVH1 4UY81 5DM71 5GAEc 5GAHc 4V196 5H1Sc 4U671 5GAGc 3PIO1
chains in the Genus database with same CATH superfamily
4JAEA 1RDGA 1BQ9A 2NVYL 3GTQL 5H1Sc 2XJVA 2E2HL 2E2JL 1R0FA 2HR5A 2XJTA 3HOUL 1CADA 1R0IA 4Y7NL 2DSXA 3NFPI 2R92L 1R0GA 1PZXA 3QVDA 2B63L 1R0HA 4TPUA 1DVBA 1FHMA 1B71A 4AI3A 2O5JD 4ME3A 1CAAA 4A3ML 5JVG1 4YWLA 3GTLL 3QQCE 1VZIA 3S16L 3K35A 5IYCL 1LKOA 2CKAA 4A3EL 2PVEA 4A3DL 4AI1A 3S1RL 1SMWA 1T9QA 3KYUA 5C44L 3RZOL 5IYDL 1B13A 1WJVA 1T9PA 5C4JL 1RWDA 4GS7D 3PKIA 3KYWA 3H0GL 1F4LA 2APOB 5FJ8L 1R0JA 3GTOL 4JADA 8RXNA 1VCXA 2PSMC 4C3HL 3S1QL 5DM61 3PIP1 2YU9L 2A6ED 2GMGA 1B2OA 2E2IL 1PFYA 3RZTA 3KYYA 5IP9L 1FHHA 3LNLA 5AN9H 1NXEA 1PFVA 4AHYA 2M6OA 2VUML 3KYXA 1S2ZA 3RYGA 2XJUA 5GAGc 2AQCA 4WFN1 2A68D 4C3JL 4UY81 1QYBA 4A3CL 4A3IL 4A3JL 2C6AA 5RXNA 4TVMA 1RYQA 2PMZP 5MFPA 3PL5A 2JA8L 3P8BA 3PZAA 1TWAL 7RXNA 1ZRPA 1PFWA 4POGA 4BY1L 2JA6L 1SMUA 2KKDA 3GTKL 4AR6A 1OWCA 4BBRL 5M5YL 3GTJL 1TWFL 1QQTA 1VZGA 4U671 5IYBL 1T9OA 2VL6A 4AI2A 3FKIL 3FDJA 2R7ZL 3WWNB 3SS2A 5AI3A 1Y1WL 4A3BL 1B2JA 5MF6A 3JR7A 5GAHc 1C09A 5AI2A 3KYVA 1YUXA 3LWQB 3IU3I 4BXXL 6RXNA 4X6AL 2L0ZA 1P7PA 2ERSA 4AR3A 4BY7L 3ZG6A 2A6HD 3S1ML 3LWPB 1RB9A 4E6YA 1E8JA 2H12A 3PKJA 3J7Y1 3LPEB 4BBSL 3S17L 1OWBA 2M4YA 2NVQL 2LCQA 1S30A 2M4VA 5MLC3 2ZIXA 4A3FL 1YK4A 1SMMA 3I4ML 3H97A 1IU6A 1LKMA 5M3ML 2NYDA 2MS3A 1R9TL 3PWFA 4LHLA 3I4NL 3MSUA 4C3IL 2RFKB 2Z3QB 3HOZL 1BRFA 2AUSB 1IROA 1WCML 5C3EL 2WB1P 2CKCA 3CQZL 4AR5A 5C4XL 1NXGA 1Y1VL 3M4OL 2BE5D 3H3VM 2K2DA 2PYAA 2M6PA 4Y52L 2RDVA 1NNQA 1VZHA 2ERJA 2JI1A 3PO2L 4K9FA 2KN9A 2Z3RB 3H9BA 4A3KL 3HKZP 2Y0SP 4AHZA 1H7VA 5JVH1 5K2ME 1PFUA 4V196 5M5XL 3K7AL 4AR4A 1TWCL 3HJWB 1RYTA 4A3GL 4AHXA 3B08B 4B8CD 5GAEc 3M3YL 1BQ8A 5M5WL 2JA5L 2V0FA 3S2DL 4C2M1 1BE7A 3MPSA 1IU5A 2PVXA 3S15L 3LWOB 2NVTL 3P2AA 3J7Z1 3HAXC 1I3QL 2JA7L 4QIWP 2EY4E 3A44A 1ODHA 2V3BB 4A3LL 5EIOC 3H99A 5DM71 2R93L 2PPTA 3RZ6A 1JYBA 1TWGL 1YV1A 4AI0A 3LWRB 1LTLA 3HOVL 4G6BA 3H9CA 1RDVA 3WWLA 1SFOL 5MFZA 2CR8A 3MQKB 3S14L 1LKPA 5IY0A 1I6HL 4AYBP 4JAGA 3HOXL 2HVYC 3RZDL 1TWHL 4ZN1B 2NVXL 5EINC 2J9UB 2QL0A 4RXNA 2B5ID 2C6BA 4A93L 1S24A 1BFYA 5MGNA 4POFA 2XJPA 3B0AB 1I50L 5M3FL 3LWVB 4XXBB 1K83L 1YUZA 4JAFA 2A69D 2WAQP 4XGHA 5IP7L 2JI2A 4AHWA 3HOYL 2JI3A 2XJRA 4LHNA 3GTPL 3GTML 1IRNA 3HJYB 3VPBE 2AYJA 1IW7D 1Z92B 4YWMA 3PIO1 2V0EA 5GADc 3GTGL 1YK5A 3S1NL 1QCVA 2XJSA 3PO3L 5FLML 1DX8A 3S2HL 3HOWL 2XJQA 4ZN3B
chains in the Genus database with same CATH topology
4JAEA 3IU3I 6RXNA 1RDGA 1BQ9A 1RYTA 1B2OA 2L0ZA 3B08B 4AHXA 4B8CD 5GAEc 1BQ8A 2XJQA 5H1Sc 2XJVA 2V0FA 2ERSA 1R0FA 4AR3A 2HR5A 2XJTA 3RZTA 3KYYA 1FHHA 1BE7A 3LNLA 3MPSA 1CADA 1R0IA 3ZG6A 5AN9H 2A6HD 1IU5A 1NXEA 2PVXA 2DSXA 1RB9A 3NFPI 2M6OA 4AHYA 4E6YA 1E8JA 3KYXA 3P2AA 3J7Z1 2H12A 1S2ZA 3RYGA 2XJUA 5GAGc 3A44A 3PKJA 1R0GA 4WFN1 3J7Y1 3LPEB 1ODHA 2A68D 2V3BB 5EIOC 5DM71 3QVDA 4UY81 2PPTA 1OWBA 1QYBA 2M4YA 3RZ6A 2LCQA 1JYBA 1S30A 2M4VA 5MLC3 2ZIXA 1YV1A 4AI0A 1YK4A 2C6AA 1LTLA 1SMMA 1IU6A 1LKMA 4G6BA 1RDVA 1R0HA 3WWLA 5MFZA 2CR8A 5RXNA 1LKPA 5IY0A 4TVMA 4TPUA 1RYQA 2NYDA 1DVBA 5MFPA 2MS3A 4JAGA 1FHMA 3PWFA 1B71A 4LHLA 4AI3A 3MSUA 4ZN1B 5EINC 3P8BA 2Z3QB 3PZAA 2J9UB 7RXNA 1ZRPA 2QL0A 4RXNA 1BRFA 4ME3A 2O5JD 2B5ID 2C6BA 1CAAA 1S24A 1IROA 4POGA 5JVG1 1BFYA 4YWLA 1SMUA 5MGNA 4POFA 2KKDA 4AR6A 3QQCE 1OWCA 1VZIA 2XJPA 3B0AB 2CKCA 3K35A 4AR5A 1LKOA 2CKAA 4XXBB 1NXGA 2PVEA 1YUZA 4JAFA 2BE5D 2A69D 4AI1A 4XGHA 2K2DA 2PYAA 2JI2A 1SMWA 2M6PA 4AHWA 1T9QA 2JI3A 2RDVA 3KYUA 1VZGA 2XJRA 4LHNA 1NNQA 1VZHA 2ERJA 1B13A 1IRNA 4U671 1WJVA 1T9PA 1T9OA 2VL6A 2JI1A 4AI2A 4K9FA 1RWDA 2KN9A 2Z3RB 4GS7D 3PKIA 3KYWA 3VPBE 2AYJA 1IW7D 1Z92B 4AHZA 3WWNB 4YWMA 1H7VA 3SS2A 5JVH1 5AI3A 3PIO1 1R0JA 5K2ME 2V0EA 1B2JA 5MF6A 5GADc 1YK5A 1QCVA 2XJSA 4JADA 5GAHc 1C09A 5AI2A 8RXNA 4V196 1VCXA 2PSMC 5DM61 3PIP1 1DX8A 3KYVA 4AR4A 2A6ED 2GMGA 1YUXA 4ZN3B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WFN 1;  3J7Y 1;  5DM6 1;  3PIP 1;  5JVG 1;  5MLC 3;  3J7Z 1;  5GAD c;  5JVH 1;  4UY8 1;  5DM7 1;  5GAE c;  5GAH c;  4V19 6;  5H1S c;  4U67 1;  5GAG c;  3PIO 1; 
#chains in the Genus database with same CATH topology
 4JAE A;  1RDG A;  1BQ9 A;  2NVY L;  3GTQ L;  5H1S c;  2XJV A;  2E2H L;  2E2J L;  1R0F A;  2HR5 A;  2XJT A;  3HOU L;  1CAD A;  1R0I A;  4Y7N L;  2DSX A;  3NFP I;  2R92 L;  1R0G A;  1PZX A;  3QVD A;  2B63 L;  1R0H A;  4TPU A;  1DVB A;  1FHM A;  1B71 A;  4AI3 A;  2O5J D;  4ME3 A;  1CAA A;  4A3M L;  5JVG 1;  4YWL A;  3GTL L;  3QQC E;  1VZI A;  3S16 L;  3K35 A;  5IYC L;  1LKO A;  2CKA A;  4A3E L;  2PVE A;  4A3D L;  4AI1 A;  3S1R L;  1SMW A;  1T9Q A;  3KYU A;  5C44 L;  3RZO L;  5IYD L;  1B13 A;  1WJV A;  1T9P A;  5C4J L;  1RWD A;  4GS7 D;  3PKI A;  3KYW A;  3H0G L;  1F4L A;  2APO B;  5FJ8 L;  1R0J A;  3GTO L;  4JAD A;  8RXN A;  1VCX A;  2PSM C;  4C3H L;  3S1Q L;  5DM6 1;  3PIP 1;  2YU9 L;  2A6E D;  2GMG A;  1B2O A;  2E2I L;  1PFY A;  3RZT A;  3KYY A;  5IP9 L;  1FHH A;  3LNL A;  5AN9 H;  1NXE A;  1PFV A;  4AHY A;  2M6O A;  2VUM L;  3KYX A;  1S2Z A;  3RYG A;  2XJU A;  5GAG c;  2AQC A;  4WFN 1;  2A68 D;  4C3J L;  4UY8 1;  1QYB A;  4A3C L;  4A3I L;  4A3J L;  2C6A A;  5RXN A;  4TVM A;  1RYQ A;  2PMZ P;  5MFP A;  3PL5 A;  2JA8 L;  3P8B A;  3PZA A;  1TWA L;  7RXN A;  1ZRP A;  1PFW A;  4POG A;  4BY1 L;  2JA6 L;  1SMU A;  2KKD A;  3GTK L;  4AR6 A;  1OWC A;  4BBR L;  5M5Y L;  3GTJ L;  1TWF L;  1QQT A;  1VZG A;  4U67 1;  5IYB L;  1T9O A;  2VL6 A;  4AI2 A;  3FKI L;  3FDJ A;  2R7Z L;  3WWN B;  3SS2 A;  5AI3 A;  1Y1W L;  4A3B L;  1B2J A;  5MF6 A;  3JR7 A;  5GAH c;  1C09 A;  5AI2 A;  3KYV A;  1YUX A;  3LWQ B;  3IU3 I;  4BXX L;  6RXN A;  4X6A L;  2L0Z A;  1P7P A;  2ERS A;  4AR3 A;  4BY7 L;  3ZG6 A;  2A6H D;  3S1M L;  3LWP B;  1RB9 A;  4E6Y A;  1E8J A;  2H12 A;  3PKJ A;  3J7Y 1;  3LPE B;  4BBS L;  3S17 L;  1OWB A;  2M4Y A;  2NVQ L;  2LCQ A;  1S30 A;  2M4V A;  5MLC 3;  2ZIX A;  4A3F L;  1YK4 A;  1SMM A;  3I4M L;  3H97 A;  1IU6 A;  1LKM A;  5M3M L;  2NYD A;  2MS3 A;  1R9T L;  3PWF A;  4LHL A;  3I4N L;  3MSU A;  4C3I L;  2RFK B;  2Z3Q B;  3HOZ L;  1BRF A;  2AUS B;  1IRO A;  1WCM L;  5C3E L;  2WB1 P;  2CKC A;  3CQZ L;  4AR5 A;  5C4X L;  1NXG A;  1Y1V L;  3M4O L;  2BE5 D;  3H3V M;  2K2D A;  2PYA A;  2M6P A;  4Y52 L;  2RDV A;  1NNQ A;  1VZH A;  2ERJ A;  2JI1 A;  3PO2 L;  4K9F A;  2KN9 A;  2Z3R B;  3H9B A;  4A3K L;  3HKZ P;  2Y0S P;  4AHZ A;  1H7V A;  5JVH 1;  5K2M E;  1PFU A;  4V19 6;  5M5X L;  3K7A L;  4AR4 A;  1TWC L;  3HJW B;  1RYT A;  4A3G L;  4AHX A;  3B08 B;  4B8C D;  5GAE c;  3M3Y L;  1BQ8 A;  5M5W L;  2JA5 L;  2V0F A;  3S2D L;  4C2M 1;  1BE7 A;  3MPS A;  1IU5 A;  2PVX A;  3S15 L;  3LWO B;  2NVT L;  3P2A A;  3J7Z 1;  3HAX C;  1I3Q L;  2JA7 L;  4QIW P;  2EY4 E;  3A44 A;  1ODH A;  2V3B B;  4A3L L;  5EIO C;  3H99 A;  5DM7 1;  2R93 L;  2PPT A;  3RZ6 A;  1JYB A;  1TWG L;  1YV1 A;  4AI0 A;  3LWR B;  1LTL A;  3HOV L;  4G6B A;  3H9C A;  1RDV A;  3WWL A;  1SFO L;  5MFZ A;  2CR8 A;  3MQK B;  3S14 L;  1LKP A;  5IY0 A;  1I6H L;  4AYB P;  4JAG A;  3HOX L;  2HVY C;  3RZD L;  1TWH L;  4ZN1 B;  2NVX L;  5EIN C;  2J9U B;  2QL0 A;  4RXN A;  2B5I D;  2C6B A;  4A93 L;  1S24 A;  1BFY A;  5MGN A;  4POF A;  2XJP A;  3B0A B;  1I50 L;  5M3F L;  3LWV B;  4XXB B;  1K83 L;  1YUZ A;  4JAF A;  2A69 D;  2WAQ P;  4XGH A;  5IP7 L;  2JI2 A;  4AHW A;  3HOY L;  2JI3 A;  2XJR A;  4LHN A;  3GTP L;  3GTM L;  1IRN A;  3HJY B;  3VPB E;  2AYJ A;  1IW7 D;  1Z92 B;  4YWM A;  3PIO 1;  2V0E A;  5GAD c;  3GTG L;  1YK5 A;  3S1N L;  1QCV A;  2XJS A;  3PO3 L;  5FLM L;  1DX8 A;  3S2H L;  3HOW L;  2XJQ A;  4ZN3 B; 
#chains in the Genus database with same CATH homology
 4JAE A;  3IU3 I;  6RXN A;  1RDG A;  1BQ9 A;  1RYT A;  1B2O A;  2L0Z A;  3B08 B;  4AHX A;  4B8C D;  5GAE c;  1BQ8 A;  2XJQ A;  5H1S c;  2XJV A;  2V0F A;  2ERS A;  1R0F A;  4AR3 A;  2HR5 A;  2XJT A;  3RZT A;  3KYY A;  1FHH A;  1BE7 A;  3LNL A;  3MPS A;  1CAD A;  1R0I A;  3ZG6 A;  5AN9 H;  2A6H D;  1IU5 A;  1NXE A;  2PVX A;  2DSX A;  1RB9 A;  3NFP I;  2M6O A;  4AHY A;  4E6Y A;  1E8J A;  3KYX A;  3P2A A;  3J7Z 1;  2H12 A;  1S2Z A;  3RYG A;  2XJU A;  5GAG c;  3A44 A;  3PKJ A;  1R0G A;  4WFN 1;  3J7Y 1;  3LPE B;  1ODH A;  2A68 D;  2V3B B;  5EIO C;  5DM7 1;  3QVD A;  4UY8 1;  2PPT A;  1OWB A;  1QYB A;  2M4Y A;  3RZ6 A;  2LCQ A;  1JYB A;  1S30 A;  2M4V A;  5MLC 3;  2ZIX A;  1YV1 A;  4AI0 A;  1YK4 A;  2C6A A;  1LTL A;  1SMM A;  1IU6 A;  1LKM A;  4G6B A;  1RDV A;  1R0H A;  3WWL A;  5MFZ A;  2CR8 A;  5RXN A;  1LKP A;  5IY0 A;  4TVM A;  4TPU A;  1RYQ A;  2NYD A;  1DVB A;  5MFP A;  2MS3 A;  4JAG A;  1FHM A;  3PWF A;  1B71 A;  4LHL A;  4AI3 A;  3MSU A;  4ZN1 B;  5EIN C;  3P8B A;  2Z3Q B;  3PZA A;  2J9U B;  7RXN A;  1ZRP A;  2QL0 A;  4RXN A;  1BRF A;  4ME3 A;  2O5J D;  2B5I D;  2C6B A;  1CAA A;  1S24 A;  1IRO A;  4POG A;  5JVG 1;  1BFY A;  4YWL A;  1SMU A;  5MGN A;  4POF A;  2KKD A;  4AR6 A;  3QQC E;  1OWC A;  1VZI A;  2XJP A;  3B0A B;  2CKC A;  3K35 A;  4AR5 A;  1LKO A;  2CKA A;  4XXB B;  1NXG A;  2PVE A;  1YUZ A;  4JAF A;  2BE5 D;  2A69 D;  4AI1 A;  4XGH A;  2K2D A;  2PYA A;  2JI2 A;  1SMW A;  2M6P A;  4AHW A;  1T9Q A;  2JI3 A;  2RDV A;  3KYU A;  1VZG A;  2XJR A;  4LHN A;  1NNQ A;  1VZH A;  2ERJ A;  1B13 A;  1IRN A;  4U67 1;  1WJV A;  1T9P A;  1T9O A;  2VL6 A;  2JI1 A;  4AI2 A;  4K9F A;  1RWD A;  2KN9 A;  2Z3R B;  4GS7 D;  3PKI A;  3KYW A;  3VPB E;  2AYJ A;  1IW7 D;  1Z92 B;  4AHZ A;  3WWN B;  4YWM A;  1H7V A;  3SS2 A;  5JVH 1;  5AI3 A;  3PIO 1;  1R0J A;  5K2M E;  2V0E A;  1B2J A;  5MF6 A;  5GAD c;  1YK5 A;  1QCV A;  2XJS A;  4JAD A;  5GAH c;  1C09 A;  5AI2 A;  8RXN A;  4V19 6;  1VCX A;  2PSM C;  5DM6 1;  3PIP 1;  1DX8 A;  3KYV A;  4AR4 A;  2A6E D;  2GMG A;  1YUX A;  4ZN3 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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