5M5WL

Rna polymerase i open complex
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
43
structure length
43
Chain Sequence
KYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular Structures of Transcribing RNA Polymerase I.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-directed RNA polymerase I subunit RPA190
total genus 1
structure length 43
sequence length 43
ec nomenclature
pdb deposition date 2016-10-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 5m5wL00
4A3EL 3GTOL 5M5YL 5C3EL 3FKIL 4C3IL 2VUML 5IYCL 3S14L 3RZOL 1WCML 3HOWL 5M5XL 3HOUL 3HOYL 4BY7L 2YU9L 3I4ML 4A3JL 3K7AL 3S1QL 4A3LL 2Y0SP 1I50L 5M3ML 2PMZP 2JA5L 1TWHL 1TWAL 5M5WL 3S2DL 2E2JL 3S17L 1TWCL 5IP7L 4A3FL 4X6AL 1I6HL 3I4NL 2NVXL 1Y1WL 3GTLL 3GTGL 1I3QL 2B63L 3HOVL 1SFOL 5FLML 4BBSL 3S16L 4A3IL 2JA7L 2R93L 2R7ZL 3H3VM 2E2IL 3S2HL 3GTJL 2WB1P 4C2M1 2NVQL 4C3JL 4A93L 3H0GL 4C3HL 4A3DL 3M4OL 3S1ML 5C4JL 1TWGL 2R92L 3CQZL 1R9TL 2JA8L 5C4XL 3HKZP 2WAQP 3PO3L 4AYBP 4BXXL 5IYDL 4A3BL 3HOZL 4QIWP 3RZDL 4BY1L 3GTKL 3GTPL 5C44L 2NVYL 4Y7NL 3S1NL 1K83L 3S15L 4Y52L 5M3FL 1Y1VL 3M3YL 3PO2L 5FJ8L 4A3ML 2NVTL 3HOXL 1TWFL 4BBRL 5IYBL 2E2HL 3S1RL 5IP9L 2JA6L 3GTML 4A3GL 3GTQL 4A3KL 4A3CL
chains in the Genus database with same CATH superfamily
1LKMA 2Z3QB 3B08B 4WFN1 2M6OA 4AI0A 1RYQA 2V0FA 3RZOL 3HOYL 5MFPA 1NXGA 2Z3RB 1YUXA 2ERSA 4POGA 2Y0SP 2PMZP 3LWRB 3J7Y1 3S2DL 4AR3A 4V196 3A44A 3GTLL 1IROA 1PFUA 3HOVL 5FLML 4JAFA 4A3IL 2MS3A 2R7ZL 3S2HL 2NYDA 5AI3A 2M4YA 2J9UB 3RYGA 1DX8A 1R0JA 2ERJA 3PL5A 1SMWA 3M4OL 4AHXA 1R9TL 3CQZL 2XJQA 2CR8A 3HKZP 3PO3L 2PVXA 4ME3A 1PZXA 4QIWP 3LNLA 3GTKL 3QQCE 1B71A 1PFYA 4XGHA 2L0ZA 3HJYB 3PO2L 5FJ8L 3LWPB 3WWNB 5IYBL 1S30A 2GMGA 1VZGA 1B13A 2H12A 3KYXA 4XXBB 2CKCA 3GTOL 2K2DA 2V3BB 3LWVB 1T9OA 2RDVA 5C3EL 3FKIL 3RZ6A 5IYCL 3HOUL 5JVG1 5MFZA 1R0HA 4A3LL 2CKAA 2A69D 3SS2A 3P2AA 2JA5L 4JADA 1TWAL 3JR7A 1S24A 5MGNA 4JAEA 5JVH1 3RZTA 5IP7L 4A3FL 4X6AL 1Y1WL 5EINC 3MPSA 1SFOL 2JI2A 2AQCA 4YWLA 4AR5A 3ZG6A 2XJVA 2VL6A 1FHMA 4AHWA 3H3VM 3PKJA 2E2IL 4POFA 2WB1P 2JI1A 4TVMA 2XJTA 1YV1A 4C3JL 3KYUA 5AN9H 3PZAA 5GAEc 3QVDA 5GADc 2XJUA 4AR4A 2LCQA 5H1Sc 2WAQP 2ZIXA 5IYDL 3KYWA 4U671 5EIOC 1VZIA 2AYJA 1SMMA 5C44L 2NVYL 2V0EA 3S1NL 3LWOB 2AUSB 1K83L 5M3FL 3B0AB 1P7PA 4A3ML 6RXNA 1TWFL 1BQ8A 3HAXC 2O5JD 2JA6L 2BE5D 4A3GL 4A3DL 4A3CL 1IW7D 4A3EL 1PFWA 5M5YL 3H9BA 3MSUA 2VUML 3KYYA 3S14L 8RXNA 3HOWL 4BY7L 2YU9L 1ZRPA 3K7AL 2XJPA 2PVEA 3P8BA 3H9CA 2HVYC 4GS7D 1LKOA 4LHLA 1TWHL 1BE7A 5M5WL 5MLC3 3S17L 7RXNA 1QCVA 1BFYA 3PKIA 1T9PA 3I4NL 2NVXL 1IRNA 1RWDA 2M4VA 4JAGA 1I3QL 4AI1A 5GAGc 3GTGL 4AHZA 2PYAA 3PWFA 2B5ID 5RXNA 3GTJL 2A6HD 4C2M1 2NVQL 5DM61 1RYTA 4ZN3B 1R0GA 3H0GL 1LKPA 3PIP1 5GAHc 4RXNA 2QL0A 3K35A 1TWGL 1YK4A 5C4JL 1WJVA 4G6BA 1YK5A 1VZHA 2PPTA 1NNQA 5C4XL 4B8CD 1SMUA 2PSMC 4AYBP 1QQTA 3HOZL 4ZN1B 4BY1L 1S2ZA 3KYVA 3GTPL 4Y7NL 1R0IA 2KKDA 3M3YL 3IU3I 2EY4E 3HOXL 4BBRL 3HJWB 2E2HL 2C6AA 3S1RL 2XJSA 5IP9L 1T9QA 2KN9A 1RB9A 2C6BA 4K9FA 2M6PA 4YWMA 3LWQB 1CAAA 1BQ9A 4C3IL 1IU6A 1JYBA 5IY0A 1WCML 5M5XL 3I4ML 4A3JL 2JI3A 3S1QL 2APOB 1FHHA 1PFVA 1BRFA 1I50L 5M3ML 3H97A 1DVBA 1B2OA 1OWBA 2E2JL 4A3KL 1F4LA 1TWCL 3J7Z1 1I6HL 3LPEB 3WWLA 2B63L 2RFKB 4BBSL 3S16L 2JA7L 2R93L 5AI2A 1C09A 5MF6A 1VCXA 4AI3A 4AI2A 1Z92B 3NFPI 3PIO1 3VPBE 4A93L 4AR6A 1IU5A 1CADA 1LTLA 4C3HL 1H7VA 1YUZA 3S1ML 3H99A 4AHYA 1ODHA 2R92L 4UY81 1E8JA 2JA8L 1RDGA 1R0FA 4TPUA 4BXXL 4A3BL 1RDVA 2XJRA 1B2JA 3RZDL 2HR5A 1NXEA 3MQKB 2A6ED 3S15L 1QYBA 1OWCA 4LHNA 4Y52L 1Y1VL 3FDJA 2NVTL 5DM71 5K2ME 2A68D 3GTML 3GTQL 4E6YA 2DSXA
chains in the Genus database with same CATH topology
4A3EL 3GTOL 5M5YL 5C3EL 3FKIL 4C3IL 2VUML 5IYCL 3S14L 3RZOL 1WCML 3HOWL 5M5XL 3HOUL 3HOYL 4BY7L 2YU9L 3I4ML 4A3JL 3K7AL 3S1QL 4A3LL 2Y0SP 1I50L 5M3ML 2PMZP 2JA5L 1TWHL 1TWAL 5M5WL 3S2DL 2E2JL 3S17L 1TWCL 5IP7L 4A3FL 4X6AL 1I6HL 3I4NL 2NVXL 1Y1WL 3GTLL 3GTGL 1I3QL 2B63L 3HOVL 1SFOL 5FLML 4BBSL 3S16L 4A3IL 2JA7L 2R93L 2R7ZL 3H3VM 2E2IL 3S2HL 3GTJL 2WB1P 4C2M1 2NVQL 4C3JL 4A93L 3H0GL 4C3HL 4A3DL 3M4OL 3S1ML 5C4JL 1TWGL 2R92L 3CQZL 1R9TL 2JA8L 5C4XL 3HKZP 2WAQP 3PO3L 4AYBP 4BXXL 5IYDL 4A3BL 3HOZL 4QIWP 3RZDL 4BY1L 3GTKL 3GTPL 5C44L 2NVYL 4Y7NL 3S1NL 1K83L 3S15L 4Y52L 5M3FL 1Y1VL 3M3YL 3PO2L 5FJ8L 4A3ML 2NVTL 3HOXL 1TWFL 4BBRL 5IYBL 2E2HL 3S1RL 5IP9L 2JA6L 3GTML 4A3GL 3GTQL 4A3KL 4A3CL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3E L;  3GTO L;  5M5Y L;  5C3E L;  3FKI L;  4C3I L;  2VUM L;  5IYC L;  3S14 L;  3RZO L;  1WCM L;  3HOW L;  5M5X L;  3HOU L;  3HOY L;  4BY7 L;  2YU9 L;  3I4M L;  4A3J L;  3K7A L;  3S1Q L;  4A3L L;  2Y0S P;  1I50 L;  5M3M L;  2PMZ P;  2JA5 L;  1TWH L;  1TWA L;  5M5W L;  3S2D L;  2E2J L;  3S17 L;  1TWC L;  5IP7 L;  4A3F L;  4X6A L;  1I6H L;  3I4N L;  2NVX L;  1Y1W L;  3GTL L;  3GTG L;  1I3Q L;  2B63 L;  3HOV L;  1SFO L;  5FLM L;  4BBS L;  3S16 L;  4A3I L;  2JA7 L;  2R93 L;  2R7Z L;  3H3V M;  2E2I L;  3S2H L;  3GTJ L;  2WB1 P;  4C2M 1;  2NVQ L;  4C3J L;  4A93 L;  3H0G L;  4C3H L;  4A3D L;  3M4O L;  3S1M L;  5C4J L;  1TWG L;  2R92 L;  3CQZ L;  1R9T L;  2JA8 L;  5C4X L;  3HKZ P;  2WAQ P;  3PO3 L;  4AYB P;  4BXX L;  5IYD L;  4A3B L;  3HOZ L;  4QIW P;  3RZD L;  4BY1 L;  3GTK L;  3GTP L;  5C44 L;  2NVY L;  4Y7N L;  3S1N L;  1K83 L;  3S15 L;  4Y52 L;  5M3F L;  1Y1V L;  3M3Y L;  3PO2 L;  5FJ8 L;  4A3M L;  2NVT L;  3HOX L;  1TWF L;  4BBR L;  5IYB L;  2E2H L;  3S1R L;  5IP9 L;  2JA6 L;  3GTM L;  4A3G L;  3GTQ L;  4A3K L;  4A3C L; 
#chains in the Genus database with same CATH topology
 1LKM A;  2Z3Q B;  3B08 B;  4WFN 1;  2M6O A;  4AI0 A;  1RYQ A;  2V0F A;  3RZO L;  3HOY L;  5MFP A;  1NXG A;  2Z3R B;  1YUX A;  2ERS A;  4POG A;  2Y0S P;  2PMZ P;  3LWR B;  3J7Y 1;  3S2D L;  4AR3 A;  4V19 6;  3A44 A;  3GTL L;  1IRO A;  1PFU A;  3HOV L;  5FLM L;  4JAF A;  4A3I L;  2MS3 A;  2R7Z L;  3S2H L;  2NYD A;  5AI3 A;  2M4Y A;  2J9U B;  3RYG A;  1DX8 A;  1R0J A;  2ERJ A;  3PL5 A;  1SMW A;  3M4O L;  4AHX A;  1R9T L;  3CQZ L;  2XJQ A;  2CR8 A;  3HKZ P;  3PO3 L;  2PVX A;  4ME3 A;  1PZX A;  4QIW P;  3LNL A;  3GTK L;  3QQC E;  1B71 A;  1PFY A;  4XGH A;  2L0Z A;  3HJY B;  3PO2 L;  5FJ8 L;  3LWP B;  3WWN B;  5IYB L;  1S30 A;  2GMG A;  1VZG A;  1B13 A;  2H12 A;  3KYX A;  4XXB B;  2CKC A;  3GTO L;  2K2D A;  2V3B B;  3LWV B;  1T9O A;  2RDV A;  5C3E L;  3FKI L;  3RZ6 A;  5IYC L;  3HOU L;  5JVG 1;  5MFZ A;  1R0H A;  4A3L L;  2CKA A;  2A69 D;  3SS2 A;  3P2A A;  2JA5 L;  4JAD A;  1TWA L;  3JR7 A;  1S24 A;  5MGN A;  4JAE A;  5JVH 1;  3RZT A;  5IP7 L;  4A3F L;  4X6A L;  1Y1W L;  5EIN C;  3MPS A;  1SFO L;  2JI2 A;  2AQC A;  4YWL A;  4AR5 A;  3ZG6 A;  2XJV A;  2VL6 A;  1FHM A;  4AHW A;  3H3V M;  3PKJ A;  2E2I L;  4POF A;  2WB1 P;  2JI1 A;  4TVM A;  2XJT A;  1YV1 A;  4C3J L;  3KYU A;  5AN9 H;  3PZA A;  5GAE c;  3QVD A;  5GAD c;  2XJU A;  4AR4 A;  2LCQ A;  5H1S c;  2WAQ P;  2ZIX A;  5IYD L;  3KYW A;  4U67 1;  5EIO C;  1VZI A;  2AYJ A;  1SMM A;  5C44 L;  2NVY L;  2V0E A;  3S1N L;  3LWO B;  2AUS B;  1K83 L;  5M3F L;  3B0A B;  1P7P A;  4A3M L;  6RXN A;  1TWF L;  1BQ8 A;  3HAX C;  2O5J D;  2JA6 L;  2BE5 D;  4A3G L;  4A3D L;  4A3C L;  1IW7 D;  4A3E L;  1PFW A;  5M5Y L;  3H9B A;  3MSU A;  2VUM L;  3KYY A;  3S14 L;  8RXN A;  3HOW L;  4BY7 L;  2YU9 L;  1ZRP A;  3K7A L;  2XJP A;  2PVE A;  3P8B A;  3H9C A;  2HVY C;  4GS7 D;  1LKO A;  4LHL A;  1TWH L;  1BE7 A;  5M5W L;  5MLC 3;  3S17 L;  7RXN A;  1QCV A;  1BFY A;  3PKI A;  1T9P A;  3I4N L;  2NVX L;  1IRN A;  1RWD A;  2M4V A;  4JAG A;  1I3Q L;  4AI1 A;  5GAG c;  3GTG L;  4AHZ A;  2PYA A;  3PWF A;  2B5I D;  5RXN A;  3GTJ L;  2A6H D;  4C2M 1;  2NVQ L;  5DM6 1;  1RYT A;  4ZN3 B;  1R0G A;  3H0G L;  1LKP A;  3PIP 1;  5GAH c;  4RXN A;  2QL0 A;  3K35 A;  1TWG L;  1YK4 A;  5C4J L;  1WJV A;  4G6B A;  1YK5 A;  1VZH A;  2PPT A;  1NNQ A;  5C4X L;  4B8C D;  1SMU A;  2PSM C;  4AYB P;  1QQT A;  3HOZ L;  4ZN1 B;  4BY1 L;  1S2Z A;  3KYV A;  3GTP L;  4Y7N L;  1R0I A;  2KKD A;  3M3Y L;  3IU3 I;  2EY4 E;  3HOX L;  4BBR L;  3HJW B;  2E2H L;  2C6A A;  3S1R L;  2XJS A;  5IP9 L;  1T9Q A;  2KN9 A;  1RB9 A;  2C6B A;  4K9F A;  2M6P A;  4YWM A;  3LWQ B;  1CAA A;  1BQ9 A;  4C3I L;  1IU6 A;  1JYB A;  5IY0 A;  1WCM L;  5M5X L;  3I4M L;  4A3J L;  2JI3 A;  3S1Q L;  2APO B;  1FHH A;  1PFV A;  1BRF A;  1I50 L;  5M3M L;  3H97 A;  1DVB A;  1B2O A;  1OWB A;  2E2J L;  4A3K L;  1F4L A;  1TWC L;  3J7Z 1;  1I6H L;  3LPE B;  3WWL A;  2B63 L;  2RFK B;  4BBS L;  3S16 L;  2JA7 L;  2R93 L;  5AI2 A;  1C09 A;  5MF6 A;  1VCX A;  4AI3 A;  4AI2 A;  1Z92 B;  3NFP I;  3PIO 1;  3VPB E;  4A93 L;  4AR6 A;  1IU5 A;  1CAD A;  1LTL A;  4C3H L;  1H7V A;  1YUZ A;  3S1M L;  3H99 A;  4AHY A;  1ODH A;  2R92 L;  4UY8 1;  1E8J A;  2JA8 L;  1RDG A;  1R0F A;  4TPU A;  4BXX L;  4A3B L;  1RDV A;  2XJR A;  1B2J A;  3RZD L;  2HR5 A;  1NXE A;  3MQK B;  2A6E D;  3S15 L;  1QYB A;  1OWC A;  4LHN A;  4Y52 L;  1Y1V L;  3FDJ A;  2NVT L;  5DM7 1;  5K2M E;  2A68 D;  3GTM L;  3GTQ L;  4E6Y A;  2DSX A; 
#chains in the Genus database with same CATH homology
 4A3E L;  3GTO L;  5M5Y L;  5C3E L;  3FKI L;  4C3I L;  2VUM L;  5IYC L;  3S14 L;  3RZO L;  1WCM L;  3HOW L;  5M5X L;  3HOU L;  3HOY L;  4BY7 L;  2YU9 L;  3I4M L;  4A3J L;  3K7A L;  3S1Q L;  4A3L L;  2Y0S P;  1I50 L;  5M3M L;  2PMZ P;  2JA5 L;  1TWH L;  1TWA L;  5M5W L;  3S2D L;  2E2J L;  3S17 L;  1TWC L;  5IP7 L;  4A3F L;  4X6A L;  1I6H L;  3I4N L;  2NVX L;  1Y1W L;  3GTL L;  3GTG L;  1I3Q L;  2B63 L;  3HOV L;  1SFO L;  5FLM L;  4BBS L;  3S16 L;  4A3I L;  2JA7 L;  2R93 L;  2R7Z L;  3H3V M;  2E2I L;  3S2H L;  3GTJ L;  2WB1 P;  4C2M 1;  2NVQ L;  4C3J L;  4A93 L;  3H0G L;  4C3H L;  4A3D L;  3M4O L;  3S1M L;  5C4J L;  1TWG L;  2R92 L;  3CQZ L;  1R9T L;  2JA8 L;  5C4X L;  3HKZ P;  2WAQ P;  3PO3 L;  4AYB P;  4BXX L;  5IYD L;  4A3B L;  3HOZ L;  4QIW P;  3RZD L;  4BY1 L;  3GTK L;  3GTP L;  5C44 L;  2NVY L;  4Y7N L;  3S1N L;  1K83 L;  3S15 L;  4Y52 L;  5M3F L;  1Y1V L;  3M3Y L;  3PO2 L;  5FJ8 L;  4A3M L;  2NVT L;  3HOX L;  1TWF L;  4BBR L;  5IYB L;  2E2H L;  3S1R L;  5IP9 L;  2JA6 L;  3GTM L;  4A3G L;  3GTQ L;  4A3K L;  4A3C L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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