2Y8RA

Crystal structure of apo ama1 mutant (tyr230ala) from toxoplasma gondii
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
412
structure length
399
Chain Sequence
SGNPFQANVEMKTFMERFNLTHHHQSGIYVDLGQDKEVDGTLYREPAGLCPIWGKHIELQQPDRPPYRNNFLEDVPTEKEYKQSGNPLPGGFNLNFVTPSGQRISPFPMELLEKNSNIKASTDLGRCAEFAFKTVKATKYRYPFVYDSKKRLCHILAVSMQLMEGKKYCSVKGEPPDLTWYCFKPRKSVTENHHLIYGSAYVGENPDAFISKCPNQALRGYRFGVWKKGRCLDYTELTDTVIERVESKAQCWVKTFENDGVASDQPLTSQASWNDWWPLHQSDQPHSGGVGRNYGFYYVDTTGEGKCALSDQVPDCLVSDSAAVSYTAAGSLSEETPNFIIPSNTPPTPETALQCTADKFPDSFGACDVQACKRQKTSCVGGQIQSTSVDCTADEQNEC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Host Cell Invasion by Apicomplexan Parasites: Insights from the Co-Structure of Ama1 with a Ron2 Peptide
pubmed doi rcsb
molecule tags Membrane protein
source organism Toxoplasma gondii
molecule keywords APICAL MEMBRANE ANTIGEN, PUTATIVE
total genus 91
structure length 399
sequence length 412
chains with identical sequence B, D, E
ec nomenclature
pdb deposition date 2011-02-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02430 AMA-1 Apical membrane antigen 1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.70 Mainly Beta Ribbon Complement Module; domain 1 Complement Module; domain 1 2y8rA03
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 2y8rA01
5CS5A 1HKYA 2Q8BA 4APLA 2QJ2A 2Q8AA 4R1BA 4UAOA 5CP9A 2Y8TA 2K13X 3ZWZA 5EODA 2F83A 2HGFA 4Z0FA 1BHTA 3SRIA 3MKPA 4Z09A 4A5TS 5COEA 1GMOA 4APMA 1W8KA 3SP8A 5CT2A 2J8JA 2YIOA 5EOKA 2LL4M 5CS3A 2Y8SA 3HMTA 5CS1A 4R19A 2X2ZA 1NK1A 3HMSA 1GP9A 2YILA 5CT1A 4R1AA 5I25A 5CS9A 2LL3A 4IUAA 2Y8RA 1I8NA 2YIPA 1W81A 4R1CA 4DURA 2J8LA 4Z0EA 2Z8WA 2Z8VA 3HN4A 4Z0DA 5CSQA 3SRJA 4YIZA 3ZLDA 1Z40A 3HMRA 2QJ4A 4UV6A 5CT3A 1GMNA 3ZLEA 1YXEA
chains in the Genus database with same CATH superfamily
3OP8A 5HYUB 4N7EA 2Q8AA 2W81A 2K13X 2F83A 3GXEA 2A55A 1CKLA 1SRZA 4Z09A 1E8BA 5COEA 1HCCA 4ZH1D 3SP8A 1OJWA 1ZJKA 2YIOA 2RLQA 5FO8C 4BWCA 3K3TA 3WSXA 4A5WB 1GPZA 1G4FA 3CALA 2XRBA 4J38B 4AYDA 1HFHA 4LOSA 2W80A 1QO6A 1W81A 3TVJA 3FGTA 3OEDC 2Z8WA 2I2LA 3MQLA 4B2RA 2O39C 2RL0A 3SRJA 1Q3XA 2UWNA 1OJYA 1U5MA 3IX0A 1TPMA 5CS5A 3NFPI 2CG6A 1Z92B 4APLA 2QJ2A 4R1BA 1MD8A 4Z0FA 1H04P 1VVDA 4F4OC 1GMOA 1NWVA 2XWBF 3VWOA 3T5OA 5EOKA 4K12A 1RLHA 2XQWC 3ZD2A 1TPNA 2JGWA 1UOTP 2X2ZA 4R19A 2YILA 3KZJA 5CT1A 2LL3A 1ELVA 2JGXA 1QGBA 1MD7A 3F6KA 1I8NA 1GHQB 3O8EB 4MSLA 4PZ5A 3HN4A 2YRAA 1O9AA 3RJ3D 3ZD1A 3ZLDA 2MCYA 2ZYCA 3ERBA 2QJ4A 1GMNA 2Q8BA 2KMSA 1OJVA 1H2PP 5CP9A 2RKZA 3ZWZA 2KRIA 5EODA 1GKGA 3KXVA 4WJG2 1FBRA 1BHTA 3SRIA 4A5TS 3IU3I 2KL5A 2J8JA 5DN4A 3ZRZA 3GOVA 3FGRA 1LY2A 3R62A 5CS3A 4CSYA 2Y8SA 2BZMA 3HMTA 3NJAA 4DJZA 1OK2A 1NK1A 2IZ3A 2JRAA 5I25A 4R1AA 2V8EA 1OK1A 2RKYA 2EHFA 2QY0A 4IUAA 2Y8RA 4YNXA 4ONTD 4B2SA 2YIPA 2YBYA 1OK9A 3M7PA 5HZPB 4DURA 4Z0EA 1E88A 2EC3A 2MCZA 2Z8VA 1VVCA 4YIZA 5CT3A 3HMRA 3ZLEA 5CS9A 2WIIC 1HKYA 4LOTA 4UAOA 4YIVA 1C1ZA 2ERJA 2Y8TA 4JHSA 4KKDA 1E5GA 2HGFA 2CKUA 1GKNA 4IGDA 1SS2A 2B5ID 3MKPA 4AYMA 3L89M 3WSYA 4MUCA 3SW0X 1W8KA 4APMA 5CT2A 1H03P 1OK3A 2LL4M 2XRDA 1H2QP 3CI0J 5CS1A 1G4GA 3HMSA 1GP9A 5DN5A 1HFIA 2IZ4A 5JPMG 4FXGG 4AYEA 3OXUD 5I0QB 1TPGA 2G7IA 1QUBA 5HYPA 2RLPA 4AYIA 1PPQA 4R1CA 2J8LA 4PO7A 2XWJI 2LOJA 3INBC 3EJHA 5CSQA 1Z40A 4UV6A 4C16A 5HYTB 4Z0DA 2CG7A 1YXEA
chains in the Genus database with same CATH topology
4N7EA 2Q8AA 2K13X 2F83A 4Z09A 5COEA 3SP8A 2YIOA 4BWCA 3WSXA 1W81A 3FGTA 2Z8WA 2I2LA 3SRJA 5CS5A 4APLA 2QJ2A 4R1BA 4Z0FA 1GMOA 5EOKA 4R19A 2X2ZA 2YILA 5CT1A 2LL3A 3F6KA 1I8NA 4MSLA 3HN4A 3ZLDA 2QJ4A 1GMNA 2Q8BA 5CP9A 3ZWZA 5EODA 1BHTA 3SRIA 4A5TS 2KL5A 2J8JA 3FGRA 5CS3A 2Y8SA 3HMTA 3NJAA 1NK1A 5I25A 4R1AA 4IUAA 2Y8RA 2YIPA 4DURA 4Z0EA 2Z8VA 4YIZA 5CT3A 3HMRA 5CS9A 3ZLEA 1HKYA 4UAOA 4YIVA 2Y8TA 2HGFA 3MKPA 3WSYA 4APMA 1W8KA 5CT2A 2LL4M 5CS1A 3HMSA 1GP9A 4R1CA 2J8LA 4PO7A 4Z0DA 5CSQA 1Z40A 4UV6A 1YXEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5CS5 A;  1HKY A;  2Q8B A;  4APL A;  2QJ2 A;  2Q8A A;  4R1B A;  4UAO A;  5CP9 A;  2Y8T A;  2K13 X;  3ZWZ A;  5EOD A;  2F83 A;  2HGF A;  4Z0F A;  1BHT A;  3SRI A;  3MKP A;  4Z09 A;  4A5T S;  5COE A;  1GMO A;  4APM A;  1W8K A;  3SP8 A;  5CT2 A;  2J8J A;  2YIO A;  5EOK A;  2LL4 M;  5CS3 A;  2Y8S A;  3HMT A;  5CS1 A;  4R19 A;  2X2Z A;  1NK1 A;  3HMS A;  1GP9 A;  2YIL A;  5CT1 A;  4R1A A;  5I25 A;  5CS9 A;  2LL3 A;  4IUA A;  2Y8R A;  1I8N A;  2YIP A;  1W81 A;  4R1C A;  4DUR A;  2J8L A;  4Z0E A;  2Z8W A;  2Z8V A;  3HN4 A;  4Z0D A;  5CSQ A;  3SRJ A;  4YIZ A;  3ZLD A;  1Z40 A;  3HMR A;  2QJ4 A;  4UV6 A;  5CT3 A;  1GMN A;  3ZLE A;  1YXE A; 
#chains in the Genus database with same CATH topology
 3OP8 A;  5HYU B;  4N7E A;  2Q8A A;  2W81 A;  2K13 X;  2F83 A;  3GXE A;  2A55 A;  1CKL A;  1SRZ A;  4Z09 A;  1E8B A;  5COE A;  1HCC A;  4ZH1 D;  3SP8 A;  1OJW A;  1ZJK A;  2YIO A;  2RLQ A;  5FO8 C;  4BWC A;  3K3T A;  3WSX A;  4A5W B;  1GPZ A;  1G4F A;  3CAL A;  2XRB A;  4J38 B;  4AYD A;  1HFH A;  4LOS A;  2W80 A;  1QO6 A;  1W81 A;  3TVJ A;  3FGT A;  3OED C;  2Z8W A;  2I2L A;  3MQL A;  4B2R A;  2O39 C;  2RL0 A;  3SRJ A;  1Q3X A;  2UWN A;  1OJY A;  1U5M A;  3IX0 A;  1TPM A;  5CS5 A;  3NFP I;  2CG6 A;  1Z92 B;  4APL A;  2QJ2 A;  4R1B A;  1MD8 A;  4Z0F A;  1H04 P;  1VVD A;  4F4O C;  1GMO A;  1NWV A;  2XWB F;  3VWO A;  3T5O A;  5EOK A;  4K12 A;  1RLH A;  2XQW C;  3ZD2 A;  1TPN A;  2JGW A;  1UOT P;  2X2Z A;  4R19 A;  2YIL A;  3KZJ A;  5CT1 A;  2LL3 A;  1ELV A;  2JGX A;  1QGB A;  1MD7 A;  3F6K A;  1I8N A;  1GHQ B;  3O8E B;  4MSL A;  4PZ5 A;  3HN4 A;  2YRA A;  1O9A A;  3RJ3 D;  3ZD1 A;  3ZLD A;  2MCY A;  2ZYC A;  3ERB A;  2QJ4 A;  1GMN A;  2Q8B A;  2KMS A;  1OJV A;  1H2P P;  5CP9 A;  2RKZ A;  3ZWZ A;  2KRI A;  5EOD A;  1GKG A;  3KXV A;  4WJG 2;  1FBR A;  1BHT A;  3SRI A;  4A5T S;  3IU3 I;  2KL5 A;  2J8J A;  5DN4 A;  3ZRZ A;  3GOV A;  3FGR A;  1LY2 A;  3R62 A;  5CS3 A;  4CSY A;  2Y8S A;  2BZM A;  3HMT A;  3NJA A;  4DJZ A;  1OK2 A;  1NK1 A;  2IZ3 A;  2JRA A;  5I25 A;  4R1A A;  2V8E A;  1OK1 A;  2RKY A;  2EHF A;  2QY0 A;  4IUA A;  2Y8R A;  4YNX A;  4ONT D;  4B2S A;  2YIP A;  2YBY A;  1OK9 A;  3M7P A;  5HZP B;  4DUR A;  4Z0E A;  1E88 A;  2EC3 A;  2MCZ A;  2Z8V A;  1VVC A;  4YIZ A;  5CT3 A;  3HMR A;  3ZLE A;  5CS9 A;  2WII C;  1HKY A;  4LOT A;  4UAO A;  4YIV A;  1C1Z A;  2ERJ A;  2Y8T A;  4JHS A;  4KKD A;  1E5G A;  2HGF A;  2CKU A;  1GKN A;  4IGD A;  1SS2 A;  2B5I D;  3MKP A;  4AYM A;  3L89 M;  3WSY A;  4MUC A;  3SW0 X;  1W8K A;  4APM A;  5CT2 A;  1H03 P;  1OK3 A;  2LL4 M;  2XRD A;  1H2Q P;  3CI0 J;  5CS1 A;  1G4G A;  3HMS A;  1GP9 A;  5DN5 A;  1HFI A;  2IZ4 A;  5JPM G;  4FXG G;  4AYE A;  3OXU D;  5I0Q B;  1TPG A;  2G7I A;  1QUB A;  5HYP A;  2RLP A;  4AYI A;  1PPQ A;  4R1C A;  2J8L A;  4PO7 A;  2XWJ I;  2LOJ A;  3INB C;  3EJH A;  5CSQ A;  1Z40 A;  4UV6 A;  4C16 A;  5HYT B;  4Z0D A;  2CG7 A;  1YXE A; 
#chains in the Genus database with same CATH homology
 4N7E A;  2Q8A A;  2K13 X;  2F83 A;  4Z09 A;  5COE A;  3SP8 A;  2YIO A;  4BWC A;  3WSX A;  1W81 A;  3FGT A;  2Z8W A;  2I2L A;  3SRJ A;  5CS5 A;  4APL A;  2QJ2 A;  4R1B A;  4Z0F A;  1GMO A;  5EOK A;  4R19 A;  2X2Z A;  2YIL A;  5CT1 A;  2LL3 A;  3F6K A;  1I8N A;  4MSL A;  3HN4 A;  3ZLD A;  2QJ4 A;  1GMN A;  2Q8B A;  5CP9 A;  3ZWZ A;  5EOD A;  1BHT A;  3SRI A;  4A5T S;  2KL5 A;  2J8J A;  3FGR A;  5CS3 A;  2Y8S A;  3HMT A;  3NJA A;  1NK1 A;  5I25 A;  4R1A A;  4IUA A;  2Y8R A;  2YIP A;  4DUR A;  4Z0E A;  2Z8V A;  4YIZ A;  5CT3 A;  3HMR A;  5CS9 A;  3ZLE A;  1HKY A;  4UAO A;  4YIV A;  2Y8T A;  2HGF A;  3MKP A;  3WSY A;  4APM A;  1W8K A;  5CT2 A;  2LL4 M;  5CS1 A;  3HMS A;  1GP9 A;  4R1C A;  2J8L A;  4PO7 A;  4Z0D A;  5CSQ A;  1Z40 A;  4UV6 A;  1YXE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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