2Y8RA

Crystal structure of apo ama1 mutant (tyr230ala) from toxoplasma gondii
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
412
structure length
399
Chain Sequence
SGNPFQANVEMKTFMERFNLTHHHQSGIYVDLGQDKEVDGTLYREPAGLCPIWGKHIELQQPDRPPYRNNFLEDVPTEKEYKQSGNPLPGGFNLNFVTPSGQRISPFPMELLEKNSNIKASTDLGRCAEFAFKTVKATKYRYPFVYDSKKRLCHILAVSMQLMEGKKYCSVKGEPPDLTWYCFKPRKSVTENHHLIYGSAYVGENPDAFISKCPNQALRGYRFGVWKKGRCLDYTELTDTVIERVESKAQCWVKTFENDGVASDQPLTSQASWNDWWPLHQSDQPHSGGVGRNYGFYYVDTTGEGKCALSDQVPDCLVSDSAAVSYTAAGSLSEETPNFIIPSNTPPTPETALQCTADKFPDSFGACDVQACKRQKTSCVGGQIQSTSVDCTADEQNEC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Host Cell Invasion by Apicomplexan Parasites: Insights from the Co-Structure of Ama1 with a Ron2 Peptide
pubmed doi rcsb
molecule tags Membrane protein
source organism Toxoplasma gondii
molecule keywords APICAL MEMBRANE ANTIGEN, PUTATIVE
total genus 91
structure length 399
sequence length 412
chains with identical sequence B, D, E
ec nomenclature
pdb deposition date 2011-02-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02430 AMA-1 Apical membrane antigen 1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.70 Mainly Beta Ribbon Complement Module; domain 1 Complement Module; domain 1 2y8rA03
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 2y8rA01
3HMSA 2Y8RA 3MKPA 5CS3A 2QJ2A 2X2ZA 1GP9A 4UAOA 4IUAA 2Z8WA 3SP8A 1HKYA 3HMTA 2LL3A 2F83A 5CS5A 5CP9A 2QJ4A 4APLA 1NK1A 1GMOA 1W8KA 2YIPA 5EODA 2HGFA 2K13X 2J8JA 3HN4A 5COEA 1YXEA 4Z09A 4R1AA 4A5TS 4R19A 3SRJA 3ZLEA 2Q8BA 4R1CA 5CT1A 5CSQA 1W81A 1I8NA 5CS1A 4DURA 5CT2A 2J8LA 2Y8SA 1BHTA 4YIZA 1Z40A 2Z8VA 4UV6A 3ZLDA 2YILA 2Q8AA 4Z0DA 5EOKA 4Z0EA 3SRIA 3ZWZA 4Z0FA 4APMA 2LL4M 2Y8TA 5I25A 4R1BA 2YIOA 3HMRA 5CT3A 1GMNA 5CS9A
chains in the Genus database with same CATH superfamily
3K3TA 2BZMA 1HFHA 3MKPA 3CI0J 3FGTA 1Z92B 2UWNA 4UAOA 1ZJKA 4IUAA 3F6KA 2XWBF 2F83A 5CS5A 4LOTA 4APLA 2XRDA 2EC3A 3GXEA 2YRAA 3TVJA 1TPGA 1GPZA 3M7PA 5EODA 3HN4A 3MQLA 2J8JA 5COEA 3INBC 2G7IA 5HYTB 1C1ZA 2JRAA 2W81A 1RLHA 1E8BA 1VVDA 3VWOA 1OK3A 1G4GA 3OEDC 4DURA 4ONTD 2KL5A 2J8LA 2Y8SA 1PPQA 1Q3XA 2Z8VA 4UV6A 1QO6A 5EOKA 2YILA 4AYMA 2ZYCA 4APMA 3IX0A 2LL4M 3WSYA 1OK1A 3FGRA 2Y8TA 3ZD1A 2IZ4A 3O8EB 4MSLA 1ELVA 3RJ3D 4C16A 4A5WB 2RL0A 2QJ2A 1HKYA 2Z8WA 4K12A 1H2QP 3EJHA 5FO8C 2EHFA 3L89M 2MCZA 5CP9A 1HCCA 2RKZA 3CALA 1GMOA 2ERJA 2YIPA 2K13X 4DJZA 2YBYA 1MD8A 4R1AA 1GKGA 4A5TS 1GKNA 4R19A 3SRJA 2RKYA 4KKDA 5DN5A 1I8NA 3GOVA 2KRIA 5CT2A 4LOSA 4YIZA 1E5GA 1UOTP 3IU3I 2A55A 4PO7A 5HZPB 3SRIA 4Z0FA 4JHSA 4B2SA 5I25A 1SS2A 1TPNA 2RLQA 2WIIC 4R1BA 2RLPA 2CG6A 2B5ID 1H03P 4WJG2 3ZRZA 2Y8RA 1TPMA 4AYIA 2KMSA 3ZD2A 1OK9A 1QUBA 1GP9A 1OJWA 3HMTA 2XRBA 3NFPI 1W8KA 3T5OA 1OK2A 4J38B 1YXEA 4Z09A 1QGBA 2W80A 3ZLEA 4AYEA 5HYPA 2Q8BA 5CT1A 5CSQA 1W81A 1H2PP 5CS1A 2JGXA 4N7EA 1FBRA 1BHTA 4MUCA 3NJAA 2JGWA 3ZLDA 4IGDA 4B2RA 2Q8AA 4CSYA 3ERBA 3ZWZA 2IZ3A 2V8EA 2CKUA 1H04P 2YIOA 5I0QB 1GMNA 2LOJA 2I2LA 3SW0X 2HGFA 2O39C 3HMSA 5CS9A 4PZ5A 5CS3A 3OP8A 3R62A 5JPMG 2X2ZA 3SP8A 1VVCA 1HFIA 5HYUB 4FXGG 1E88A 1SRZA 2LL3A 2QJ4A 2CG7A 1NK1A 5DN4A 4F4OC 2MCYA 3KXVA 4ZH1D 1CKLA 1G4FA 3KZJA 4R1CA 2XWJI 2XQWC 1GHQB 4YIVA 4BWCA 1Z40A 4Z0DA 4Z0EA 3OXUD 1MD7A 1O9AA 3WSXA 4AYDA 1LY2A 1U5MA 4YNXA 2QY0A 1OJYA 1OJVA 3HMRA 5CT3A 1NWVA
chains in the Genus database with same CATH topology
3MKPA 3FGTA 4UAOA 4IUAA 3F6KA 2F83A 5CS5A 4APLA 5EODA 3HN4A 2J8JA 5COEA 4DURA 2KL5A 2J8LA 2Y8SA 5EOKA 2Z8VA 4UV6A 2YILA 4APMA 2LL4M 3WSYA 3FGRA 2Y8TA 4MSLA 2QJ2A 1HKYA 2Z8WA 5CP9A 1GMOA 2YIPA 2K13X 4R1AA 4A5TS 4R19A 3SRJA 1I8NA 5CT2A 4YIZA 4PO7A 4Z0FA 3SRIA 5I25A 4R1BA 2Y8RA 1GP9A 3HMTA 1W8KA 1YXEA 4Z09A 3ZLEA 2Q8BA 5CT1A 5CSQA 1W81A 5CS1A 4N7EA 1BHTA 3NJAA 3ZLDA 2Q8AA 3ZWZA 2YIOA 1GMNA 2HGFA 2I2LA 5CS9A 3HMSA 5CS3A 2X2ZA 3SP8A 2LL3A 2QJ4A 1NK1A 4R1CA 4YIVA 4BWCA 1Z40A 4Z0DA 4Z0EA 3WSXA 3HMRA 5CT3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HMS A;  2Y8R A;  3MKP A;  5CS3 A;  2QJ2 A;  2X2Z A;  1GP9 A;  4UAO A;  4IUA A;  2Z8W A;  3SP8 A;  1HKY A;  3HMT A;  2LL3 A;  2F83 A;  5CS5 A;  5CP9 A;  2QJ4 A;  4APL A;  1NK1 A;  1GMO A;  1W8K A;  2YIP A;  5EOD A;  2HGF A;  2K13 X;  2J8J A;  3HN4 A;  5COE A;  1YXE A;  4Z09 A;  4R1A A;  4A5T S;  4R19 A;  3SRJ A;  3ZLE A;  2Q8B A;  4R1C A;  5CT1 A;  5CSQ A;  1W81 A;  1I8N A;  5CS1 A;  4DUR A;  5CT2 A;  2J8L A;  2Y8S A;  1BHT A;  4YIZ A;  1Z40 A;  2Z8V A;  4UV6 A;  3ZLD A;  2YIL A;  2Q8A A;  4Z0D A;  5EOK A;  4Z0E A;  3SRI A;  3ZWZ A;  4Z0F A;  4APM A;  2LL4 M;  2Y8T A;  5I25 A;  4R1B A;  2YIO A;  3HMR A;  5CT3 A;  1GMN A;  5CS9 A; 
#chains in the Genus database with same CATH topology
 3K3T A;  2BZM A;  1HFH A;  3MKP A;  3CI0 J;  3FGT A;  1Z92 B;  2UWN A;  4UAO A;  1ZJK A;  4IUA A;  3F6K A;  2XWB F;  2F83 A;  5CS5 A;  4LOT A;  4APL A;  2XRD A;  2EC3 A;  3GXE A;  2YRA A;  3TVJ A;  1TPG A;  1GPZ A;  3M7P A;  5EOD A;  3HN4 A;  3MQL A;  2J8J A;  5COE A;  3INB C;  2G7I A;  5HYT B;  1C1Z A;  2JRA A;  2W81 A;  1RLH A;  1E8B A;  1VVD A;  3VWO A;  1OK3 A;  1G4G A;  3OED C;  4DUR A;  4ONT D;  2KL5 A;  2J8L A;  2Y8S A;  1PPQ A;  1Q3X A;  2Z8V A;  4UV6 A;  1QO6 A;  5EOK A;  2YIL A;  4AYM A;  2ZYC A;  4APM A;  3IX0 A;  2LL4 M;  3WSY A;  1OK1 A;  3FGR A;  2Y8T A;  3ZD1 A;  2IZ4 A;  3O8E B;  4MSL A;  1ELV A;  3RJ3 D;  4C16 A;  4A5W B;  2RL0 A;  2QJ2 A;  1HKY A;  2Z8W A;  4K12 A;  1H2Q P;  3EJH A;  5FO8 C;  2EHF A;  3L89 M;  2MCZ A;  5CP9 A;  1HCC A;  2RKZ A;  3CAL A;  1GMO A;  2ERJ A;  2YIP A;  2K13 X;  4DJZ A;  2YBY A;  1MD8 A;  4R1A A;  1GKG A;  4A5T S;  1GKN A;  4R19 A;  3SRJ A;  2RKY A;  4KKD A;  5DN5 A;  1I8N A;  3GOV A;  2KRI A;  5CT2 A;  4LOS A;  4YIZ A;  1E5G A;  1UOT P;  3IU3 I;  2A55 A;  4PO7 A;  5HZP B;  3SRI A;  4Z0F A;  4JHS A;  4B2S A;  5I25 A;  1SS2 A;  1TPN A;  2RLQ A;  2WII C;  4R1B A;  2RLP A;  2CG6 A;  2B5I D;  1H03 P;  4WJG 2;  3ZRZ A;  2Y8R A;  1TPM A;  4AYI A;  2KMS A;  3ZD2 A;  1OK9 A;  1QUB A;  1GP9 A;  1OJW A;  3HMT A;  2XRB A;  3NFP I;  1W8K A;  3T5O A;  1OK2 A;  4J38 B;  1YXE A;  4Z09 A;  1QGB A;  2W80 A;  3ZLE A;  4AYE A;  5HYP A;  2Q8B A;  5CT1 A;  5CSQ A;  1W81 A;  1H2P P;  5CS1 A;  2JGX A;  4N7E A;  1FBR A;  1BHT A;  4MUC A;  3NJA A;  2JGW A;  3ZLD A;  4IGD A;  4B2R A;  2Q8A A;  4CSY A;  3ERB A;  3ZWZ A;  2IZ3 A;  2V8E A;  2CKU A;  1H04 P;  2YIO A;  5I0Q B;  1GMN A;  2LOJ A;  2I2L A;  3SW0 X;  2HGF A;  2O39 C;  3HMS A;  5CS9 A;  4PZ5 A;  5CS3 A;  3OP8 A;  3R62 A;  5JPM G;  2X2Z A;  3SP8 A;  1VVC A;  1HFI A;  5HYU B;  4FXG G;  1E88 A;  1SRZ A;  2LL3 A;  2QJ4 A;  2CG7 A;  1NK1 A;  5DN4 A;  4F4O C;  2MCY A;  3KXV A;  4ZH1 D;  1CKL A;  1G4F A;  3KZJ A;  4R1C A;  2XWJ I;  2XQW C;  1GHQ B;  4YIV A;  4BWC A;  1Z40 A;  4Z0D A;  4Z0E A;  3OXU D;  1MD7 A;  1O9A A;  3WSX A;  4AYD A;  1LY2 A;  1U5M A;  4YNX A;  2QY0 A;  1OJY A;  1OJV A;  3HMR A;  5CT3 A;  1NWV A; 
#chains in the Genus database with same CATH homology
 3MKP A;  3FGT A;  4UAO A;  4IUA A;  3F6K A;  2F83 A;  5CS5 A;  4APL A;  5EOD A;  3HN4 A;  2J8J A;  5COE A;  4DUR A;  2KL5 A;  2J8L A;  2Y8S A;  5EOK A;  2Z8V A;  4UV6 A;  2YIL A;  4APM A;  2LL4 M;  3WSY A;  3FGR A;  2Y8T A;  4MSL A;  2QJ2 A;  1HKY A;  2Z8W A;  5CP9 A;  1GMO A;  2YIP A;  2K13 X;  4R1A A;  4A5T S;  4R19 A;  3SRJ A;  1I8N A;  5CT2 A;  4YIZ A;  4PO7 A;  4Z0F A;  3SRI A;  5I25 A;  4R1B A;  2Y8R A;  1GP9 A;  3HMT A;  1W8K A;  1YXE A;  4Z09 A;  3ZLE A;  2Q8B A;  5CT1 A;  5CSQ A;  1W81 A;  5CS1 A;  4N7E A;  1BHT A;  3NJA A;  3ZLD A;  2Q8A A;  3ZWZ A;  2YIO A;  1GMN A;  2HGF A;  2I2L A;  5CS9 A;  3HMS A;  5CS3 A;  2X2Z A;  3SP8 A;  2LL3 A;  2QJ4 A;  1NK1 A;  4R1C A;  4YIV A;  4BWC A;  1Z40 A;  4Z0D A;  4Z0E A;  3WSX A;  3HMR A;  5CT3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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