4APLA

Crystal structure of ama1 from neospora caninum
Total Genus 104
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
104
sequence length
412
structure length
398
Chain Sequence
TPQNPFQTPELKAFLERYNVTLHHQSGVNVDLGQDKEVDGKLYREAAGLCPVWGKYIQLHQPNRPPYKNNFLEDIPTEAEYQKSGNPLPGGFNMNFVTPAGQRISPYPMELLEKSSKIKASTELGKCAEFAYKTTAMDKSNQATQYRYPFVYDSKRRLCYILSVSMQRMEGSKYCSTNDDPVNLTWYCFEPQKSPTANHNLIFGSAYVGKDPDAFLTKCPNQALKGYRFGHWTNGRCHDYTELADSWIEAVDSKAQCWVKTFTNDEVASDQPRTHSWNDWWPVHEKDQPHSGGDGRNYGFFYFDSNGKGKCALSHKAPDCLVSDSKAVSYTALGSLSEETPDIIIPSNDEALQCRSSEFPETFGSCDVQACKRQKTSCVGGQIQSTSVDCTAEEQNDC
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Babesia Divergens and Neospora Caninum Apical Membrane Antigen 1 (Ama1) Structures Reveal Selectivity and Plasticity in Apicomplexan Parasite Host Cell Invasion.
pubmed doi rcsb
molecule tags Membrane protein
source organism Neospora caninum
molecule keywords APICAL MEMBRANE ANTIGEN 1
total genus 104
structure length 398
sequence length 412
chains with identical sequence B, D, E
ec nomenclature
pdb deposition date 2012-04-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02430 AMA-1 Apical membrane antigen 1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.70 Mainly Beta Ribbon Complement Module; domain 1 Complement Module; domain 1 4aplA03
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 4aplA01
5CT1A 1GP9A 1YXEA 2LL4M 1Z40A 2YILA 2LL3A 2K13X 5CSQA 2F83A 1I8NA 2X2ZA 2YIPA 3HMTA 2Z8VA 4R19A 5CP9A 4A5TS 2HGFA 4Z0EA 2Z8WA 3ZWZA 1BHTA 5CS1A 5EOKA 5EODA 5CS5A 4IUAA 3SRIA 2Q8BA 4Z0FA 5CT2A 5I25A 2J8JA 3HN4A 1GMOA 2YIOA 4R1CA 4DURA 2J8LA 3ZLDA 4Z09A 4YIZA 4APLA 4UV6A 2Y8TA 1GMNA 4R1AA 4APMA 1NK1A 4R1BA 5COEA 1HKYA 2Y8RA 3SRJA 3SP8A 4Z0DA 3HMRA 2QJ4A 5CS9A 3HMSA 2QJ2A 2Q8AA 5CT3A 3ZLEA 2Y8SA 3MKPA 1W8KA 1W81A 5CS3A 4UAOA
chains in the Genus database with same CATH superfamily
4BWCA 2LL4M 5CSQA 5CP9A 1MD7A 4Z0EA 4MSLA 5HZPB 1BHTA 2Z8WA 3OEDC 5CS1A 1LY2A 1QUBA 5EODA 1MD8A 2JGXA 5JPMG 2QY0A 2O39C 3SRIA 4Z0FA 5DN5A 1TPMA 4MUCA 1C1ZA 2YIOA 4DURA 2J8LA 3OXUD 1QGBA 3F6KA 4YIZA 4UV6A 4R1AA 2XRDA 2RLPA 4CSYA 1HKYA 2CG6A 1FBRA 1Q3XA 5HYUB 1VVCA 1ELVA 1SS2A 2XWJI 3O8EB 4JHSA 3HMRA 3HMSA 3ZLEA 1RLHA 2V8EA 1GMOA 3INBC 2I2LA 2XQWC 4A5WB 5CT1A 5DN4A 2IZ4A 3WSYA 1ZJKA 2YRAA 2G7IA 3MQLA 4KKDA 1HFIA 2RKZA 4R19A 3NFPI 2RKYA 1GHQB 3NJAA 4FXGG 5CS5A 1GKNA 3KXVA 5HYPA 2MCZA 5I25A 2J8JA 4LOTA 3VWOA 4AYEA 3TVJA 3ZLDA 4Z09A 4YIVA 2RLQA 2W81A 2Y8TA 1GMNA 3GXEA 5COEA 4DJZA 1H2PP 3CALA 2EC3A 2QJ4A 2W80A 4N7EA 2QJ2A 3RJ3D 2RL0A 1GP9A 2YILA 2LL3A 2K13X 2F83A 1I8NA 3ERBA 2XWBF 4A5TS 4ONTD 4WJG2 4K12A 4C16A 2YBYA 4IUAA 4IGDA 2IZ3A 1U5MA 4B2RA 2Q8BA 1OK9A 5CT2A 1G4GA 4PO7A 2B5ID 1O9AA 2JRAA 1TPGA 2LOJA 3T5OA 4APLA 1Z92B 2A55A 2KMSA 3R62A 3M7PA 1H04P 1HCCA 3K3TA 3WSXA 4F4OC 4AYDA 3L89M 1E5GA 5FO8C 1NK1A 4R1BA 2Y8RA 4Z0DA 1OK2A 2ZYCA 3ZD2A 1OJVA 5CS9A 2KL5A 1SRZA 2Q8AA 1CKLA 2KRIA 3MKPA 3FGTA 3CI0J 4AYMA 1W8KA 1W81A 4UAOA 5CT3A 1PPQA 2EHFA 1YXEA 3IX0A 1Z40A 4LOSA 2YIPA 2X2ZA 3OP8A 2JGWA 2Z8VA 3HMTA 2HGFA 1H03P 1OK1A 4ZH1D 2ERJA 3ZWZA 5HYTB 5I0QB 5EOKA 1OJYA 1HFHA 2BZMA 2CG7A 4YNXA 1QO6A 1G4FA 2XRBA 4PZ5A 2UWNA 4J38B 3IU3I 2WIIC 4APMA 3HN4A 1OJWA 1E8BA 4R1CA 3ZRZA 1GPZA 1E88A 2CKUA 1TPNA 1H2QP 3SRJA 3SP8A 3EJHA 1UOTP 1NWVA 3KZJA 4B2SA 1OK3A 3SW0X 2Y8SA 2MCYA 3GOVA 4AYIA 3FGRA 1VVDA 5CS3A 3ZD1A 1GKGA
chains in the Genus database with same CATH topology
4BWCA 2LL4M 5CSQA 5CP9A 4Z0EA 4MSLA 2Z8WA 1BHTA 5CS1A 5EODA 3SRIA 4Z0FA 2YIOA 4DURA 2J8LA 3F6KA 4YIZA 4UV6A 4R1AA 1HKYA 3HMRA 3HMSA 3ZLEA 1GMOA 2I2LA 5CT1A 3WSYA 4R19A 3NJAA 5CS5A 5I25A 2J8JA 3ZLDA 4Z09A 4YIVA 2Y8TA 5COEA 2QJ4A 4N7EA 2QJ2A 1GP9A 2YILA 2LL3A 2K13X 2F83A 1I8NA 4A5TS 4IUAA 2Q8BA 5CT2A 4PO7A 4APLA 3WSXA 1GMNA 4APMA 1NK1A 4R1BA 2Y8RA 4Z0DA 5CS9A 2KL5A 2Q8AA 3MKPA 3FGTA 1W8KA 1W81A 5CT3A 4UAOA 1YXEA 1Z40A 2YIPA 2X2ZA 3HMTA 2Z8VA 2HGFA 3ZWZA 5EOKA 3HN4A 4R1CA 3SRJA 3SP8A 2Y8SA 3FGRA 5CS3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5CT1 A;  1GP9 A;  1YXE A;  2LL4 M;  1Z40 A;  2YIL A;  2LL3 A;  2K13 X;  5CSQ A;  2F83 A;  1I8N A;  2X2Z A;  2YIP A;  3HMT A;  2Z8V A;  4R19 A;  5CP9 A;  4A5T S;  2HGF A;  4Z0E A;  2Z8W A;  3ZWZ A;  1BHT A;  5CS1 A;  5EOK A;  5EOD A;  5CS5 A;  4IUA A;  3SRI A;  2Q8B A;  4Z0F A;  5CT2 A;  5I25 A;  2J8J A;  3HN4 A;  1GMO A;  2YIO A;  4R1C A;  4DUR A;  2J8L A;  3ZLD A;  4Z09 A;  4YIZ A;  4APL A;  4UV6 A;  2Y8T A;  1GMN A;  4R1A A;  4APM A;  1NK1 A;  4R1B A;  5COE A;  1HKY A;  2Y8R A;  3SRJ A;  3SP8 A;  4Z0D A;  3HMR A;  2QJ4 A;  5CS9 A;  3HMS A;  2QJ2 A;  2Q8A A;  5CT3 A;  3ZLE A;  2Y8S A;  3MKP A;  1W8K A;  1W81 A;  5CS3 A;  4UAO A; 
#chains in the Genus database with same CATH topology
 4BWC A;  2LL4 M;  5CSQ A;  5CP9 A;  1MD7 A;  4Z0E A;  4MSL A;  5HZP B;  1BHT A;  2Z8W A;  3OED C;  5CS1 A;  1LY2 A;  1QUB A;  5EOD A;  1MD8 A;  2JGX A;  5JPM G;  2QY0 A;  2O39 C;  3SRI A;  4Z0F A;  5DN5 A;  1TPM A;  4MUC A;  1C1Z A;  2YIO A;  4DUR A;  2J8L A;  3OXU D;  1QGB A;  3F6K A;  4YIZ A;  4UV6 A;  4R1A A;  2XRD A;  2RLP A;  4CSY A;  1HKY A;  2CG6 A;  1FBR A;  1Q3X A;  5HYU B;  1VVC A;  1ELV A;  1SS2 A;  2XWJ I;  3O8E B;  4JHS A;  3HMR A;  3HMS A;  3ZLE A;  1RLH A;  2V8E A;  1GMO A;  3INB C;  2I2L A;  2XQW C;  4A5W B;  5CT1 A;  5DN4 A;  2IZ4 A;  3WSY A;  1ZJK A;  2YRA A;  2G7I A;  3MQL A;  4KKD A;  1HFI A;  2RKZ A;  4R19 A;  3NFP I;  2RKY A;  1GHQ B;  3NJA A;  4FXG G;  5CS5 A;  1GKN A;  3KXV A;  5HYP A;  2MCZ A;  5I25 A;  2J8J A;  4LOT A;  3VWO A;  4AYE A;  3TVJ A;  3ZLD A;  4Z09 A;  4YIV A;  2RLQ A;  2W81 A;  2Y8T A;  1GMN A;  3GXE A;  5COE A;  4DJZ A;  1H2P P;  3CAL A;  2EC3 A;  2QJ4 A;  2W80 A;  4N7E A;  2QJ2 A;  3RJ3 D;  2RL0 A;  1GP9 A;  2YIL A;  2LL3 A;  2K13 X;  2F83 A;  1I8N A;  3ERB A;  2XWB F;  4A5T S;  4ONT D;  4WJG 2;  4K12 A;  4C16 A;  2YBY A;  4IUA A;  4IGD A;  2IZ3 A;  1U5M A;  4B2R A;  2Q8B A;  1OK9 A;  5CT2 A;  1G4G A;  4PO7 A;  2B5I D;  1O9A A;  2JRA A;  1TPG A;  2LOJ A;  3T5O A;  4APL A;  1Z92 B;  2A55 A;  2KMS A;  3R62 A;  3M7P A;  1H04 P;  1HCC A;  3K3T A;  3WSX A;  4F4O C;  4AYD A;  3L89 M;  1E5G A;  5FO8 C;  1NK1 A;  4R1B A;  2Y8R A;  4Z0D A;  1OK2 A;  2ZYC A;  3ZD2 A;  1OJV A;  5CS9 A;  2KL5 A;  1SRZ A;  2Q8A A;  1CKL A;  2KRI A;  3MKP A;  3FGT A;  3CI0 J;  4AYM A;  1W8K A;  1W81 A;  4UAO A;  5CT3 A;  1PPQ A;  2EHF A;  1YXE A;  3IX0 A;  1Z40 A;  4LOS A;  2YIP A;  2X2Z A;  3OP8 A;  2JGW A;  2Z8V A;  3HMT A;  2HGF A;  1H03 P;  1OK1 A;  4ZH1 D;  2ERJ A;  3ZWZ A;  5HYT B;  5I0Q B;  5EOK A;  1OJY A;  1HFH A;  2BZM A;  2CG7 A;  4YNX A;  1QO6 A;  1G4F A;  2XRB A;  4PZ5 A;  2UWN A;  4J38 B;  3IU3 I;  2WII C;  4APM A;  3HN4 A;  1OJW A;  1E8B A;  4R1C A;  3ZRZ A;  1GPZ A;  1E88 A;  2CKU A;  1TPN A;  1H2Q P;  3SRJ A;  3SP8 A;  3EJH A;  1UOT P;  1NWV A;  3KZJ A;  4B2S A;  1OK3 A;  3SW0 X;  2Y8S A;  2MCY A;  3GOV A;  4AYI A;  3FGR A;  1VVD A;  5CS3 A;  3ZD1 A;  1GKG A; 
#chains in the Genus database with same CATH homology
 4BWC A;  2LL4 M;  5CSQ A;  5CP9 A;  4Z0E A;  4MSL A;  2Z8W A;  1BHT A;  5CS1 A;  5EOD A;  3SRI A;  4Z0F A;  2YIO A;  4DUR A;  2J8L A;  3F6K A;  4YIZ A;  4UV6 A;  4R1A A;  1HKY A;  3HMR A;  3HMS A;  3ZLE A;  1GMO A;  2I2L A;  5CT1 A;  3WSY A;  4R19 A;  3NJA A;  5CS5 A;  5I25 A;  2J8J A;  3ZLD A;  4Z09 A;  4YIV A;  2Y8T A;  5COE A;  2QJ4 A;  4N7E A;  2QJ2 A;  1GP9 A;  2YIL A;  2LL3 A;  2K13 X;  2F83 A;  1I8N A;  4A5T S;  4IUA A;  2Q8B A;  5CT2 A;  4PO7 A;  4APL A;  3WSX A;  1GMN A;  4APM A;  1NK1 A;  4R1B A;  2Y8R A;  4Z0D A;  5CS9 A;  2KL5 A;  2Q8A A;  3MKP A;  3FGT A;  1W8K A;  1W81 A;  5CT3 A;  4UAO A;  1YXE A;  1Z40 A;  2YIP A;  2X2Z A;  3HMT A;  2Z8V A;  2HGF A;  3ZWZ A;  5EOK A;  3HN4 A;  4R1C A;  3SRJ A;  3SP8 A;  2Y8S A;  3FGR A;  5CS3 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...