4APLA

Crystal structure of ama1 from neospora caninum
Total Genus 104
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
104
sequence length
412
structure length
398
Chain Sequence
TPQNPFQTPELKAFLERYNVTLHHQSGVNVDLGQDKEVDGKLYREAAGLCPVWGKYIQLHQPNRPPYKNNFLEDIPTEAEYQKSGNPLPGGFNMNFVTPAGQRISPYPMELLEKSSKIKASTELGKCAEFAYKTTAMDKSNQATQYRYPFVYDSKRRLCYILSVSMQRMEGSKYCSTNDDPVNLTWYCFEPQKSPTANHNLIFGSAYVGKDPDAFLTKCPNQALKGYRFGHWTNGRCHDYTELADSWIEAVDSKAQCWVKTFTNDEVASDQPRTHSWNDWWPVHEKDQPHSGGDGRNYGFFYFDSNGKGKCALSHKAPDCLVSDSKAVSYTALGSLSEETPDIIIPSNDEALQCRSSEFPETFGSCDVQACKRQKTSCVGGQIQSTSVDCTAEEQNDC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Babesia Divergens and Neospora Caninum Apical Membrane Antigen 1 (Ama1) Structures Reveal Selectivity and Plasticity in Apicomplexan Parasite Host Cell Invasion.
pubmed doi rcsb
molecule tags Membrane protein
source organism Neospora caninum
molecule keywords APICAL MEMBRANE ANTIGEN 1
total genus 104
structure length 398
sequence length 412
chains with identical sequence B, D, E
ec nomenclature
pdb deposition date 2012-04-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02430 AMA-1 Apical membrane antigen 1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.70 Mainly Beta Ribbon Complement Module; domain 1 Complement Module; domain 1 4aplA03
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 4aplA01
4R1CA 1GP9A 3MKPA 5CT2A 3ZLEA 2J8LA 5CT3A 2YIPA 5EODA 1GMNA 2HGFA 4R19A 1NK1A 1GMOA 5CSQA 5CS9A 3SP8A 1BHTA 2Y8SA 2Q8AA 5CS1A 3HMRA 2J8JA 1W8KA 5CT1A 4Z0FA 2X2ZA 2Y8TA 3ZLDA 2Z8VA 3HMTA 4IUAA 5COEA 3HMSA 1YXEA 3HN4A 5I25A 2F83A 4A5TS 4R1AA 2QJ2A 2QJ4A 4UAOA 4Z09A 2K13X 2Z8WA 4Z0DA 1I8NA 3SRJA 2Q8BA 4YIZA 1Z40A 2YILA 2LL4M 4DURA 5CS5A 1HKYA 1W81A 4UV6A 4Z0EA 4APMA 2LL3A 5CS3A 3SRIA 3ZWZA 5EOKA 2Y8RA 4APLA 5CP9A 4R1BA 2YIOA
chains in the Genus database with same CATH superfamily
3ERBA 1OJVA 1O9AA 4AYMA 3WSXA 2EC3A 2UWNA 1VVDA 2MCYA 1GMNA 1NK1A 1TPMA 1SS2A 4WJG2 3SP8A 4PO7A 1OJYA 1OK9A 2CG6A 3FGRA 3ZRZA 1H04P 1BHTA 2Y8SA 2IZ3A 4DJZA 1QGBA 4YNXA 2J8JA 2XRDA 1W8KA 1TPGA 5DN4A 4BWCA 5HYTB 4AYEA 5CT1A 5HYPA 1HFIA 3VWOA 3HN4A 2F83A 1G4GA 4Z09A 4UAOA 2RLQA 2G7IA 3EJHA 2Z8WA 3SRJA 2I2LA 2JGXA 1E88A 4LOSA 3CALA 4DURA 1CKLA 1Z92B 1RLHA 1ZJKA 2LL4M 4UV6A 2JGWA 4Z0EA 4APMA 3SRIA 1FBRA 5HYUB 2RL0A 2Y8RA 4APLA 5EOKA 1E8BA 2YRAA 2XRBA 4KKDA 5FO8C 5CT2A 5DN5A 3FGTA 1HCCA 1MD8A 3RJ3D 4R19A 2XQWC 1UOTP 4J38B 2O39C 1MD7A 1QUBA 4IGDA 3HMRA 3F6KA 2XWBF 1VVCA 2RKZA 3MQLA 2Y8TA 2Z8VA 3HMSA 1YXEA 2QY0A 4R1AA 1OK2A 1I8NA 3O8EB 1HFHA 1GKGA 1Z40A 2KRIA 3ZWZA 1GHQB 1SRZA 5CP9A 4FXGG 4C16A 4F4OC 4R1CA 2ERJA 1GP9A 3R62A 3IU3I 4MUCA 2W80A 2CG7A 2J8LA 5CT3A 2YIPA 5EODA 3KZJA 2RKYA 1GMOA 5CS9A 4A5WB 4JHSA 1PPQA 2V8EA 4AYIA 2B5ID 2YBYA 4LOTA 5CS1A 3K3TA 2KMSA 2KL5A 2JRAA 4Z0FA 5COEA 3HMTA 4IUAA 4YIVA 2CKUA 2QJ2A 1G4FA 2ZYCA 3GOVA 2QJ4A 1U5MA 3NFPI 4Z0DA 3ZD1A 3WSYA 2YILA 2IZ4A 4B2RA 1HKYA 1OJWA 3CI0J 5CS5A 3INBC 5CS3A 3ZD2A 3L89M 2A55A 2Q8BA 4R1BA 3GXEA 2YIOA 4AYDA 3IX0A 4PZ5A 3MKPA 4B2SA 2RLPA 3ZLEA 1GPZA 3M7PA 3OEDC 2XWJI 4CSYA 2HGFA 4N7EA 5CSQA 1H2QP 5I0QB 1GKNA 2BZMA 2LOJA 4K12A 3KXVA 5JPMG 1E5GA 2Q8AA 1NWVA 3OXUD 3SW0X 4ZH1D 2X2ZA 4ONTD 3ZLDA 2WIIC 3TVJA 1LY2A 5I25A 4MSLA 4A5TS 1OK3A 5HZPB 1H2PP 2K13X 2EHFA 1Q3XA 1C1ZA 4YIZA 1ELVA 1QO6A 3OP8A 1W81A 2W81A 1OK1A 2MCZA 1TPNA 2LL3A 3NJAA 3T5OA 1H03P
chains in the Genus database with same CATH topology
1GMNA 3WSXA 1NK1A 3SP8A 4PO7A 3FGRA 1BHTA 2Y8SA 2J8JA 1W8KA 5CT1A 4BWCA 3HN4A 2F83A 4Z09A 4UAOA 2Z8WA 3SRJA 2I2LA 4DURA 2LL4M 4UV6A 4Z0EA 4APMA 3SRIA 5EOKA 2Y8RA 4APLA 5CT2A 3FGTA 4R19A 3HMRA 3F6KA 2Y8TA 2Z8VA 3HMSA 1YXEA 4R1AA 1I8NA 1Z40A 3ZWZA 5CP9A 4R1CA 1GP9A 2J8LA 5CT3A 2YIPA 5EODA 1GMOA 5CS9A 5CS1A 2KL5A 4Z0FA 5COEA 3HMTA 4IUAA 4YIVA 2QJ2A 2QJ4A 4Z0DA 3WSYA 2YILA 1HKYA 5CS5A 5CS3A 2Q8BA 4R1BA 2YIOA 3MKPA 3ZLEA 2HGFA 4N7EA 5CSQA 2Q8AA 2X2ZA 3ZLDA 5I25A 4MSLA 4A5TS 2K13X 4YIZA 1W81A 2LL3A 3NJAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4R1C A;  1GP9 A;  3MKP A;  5CT2 A;  3ZLE A;  2J8L A;  5CT3 A;  2YIP A;  5EOD A;  1GMN A;  2HGF A;  4R19 A;  1NK1 A;  1GMO A;  5CSQ A;  5CS9 A;  3SP8 A;  1BHT A;  2Y8S A;  2Q8A A;  5CS1 A;  3HMR A;  2J8J A;  1W8K A;  5CT1 A;  4Z0F A;  2X2Z A;  2Y8T A;  3ZLD A;  2Z8V A;  3HMT A;  4IUA A;  5COE A;  3HMS A;  1YXE A;  3HN4 A;  5I25 A;  2F83 A;  4A5T S;  4R1A A;  2QJ2 A;  2QJ4 A;  4UAO A;  4Z09 A;  2K13 X;  2Z8W A;  4Z0D A;  1I8N A;  3SRJ A;  2Q8B A;  4YIZ A;  1Z40 A;  2YIL A;  2LL4 M;  4DUR A;  5CS5 A;  1HKY A;  1W81 A;  4UV6 A;  4Z0E A;  4APM A;  2LL3 A;  5CS3 A;  3SRI A;  3ZWZ A;  5EOK A;  2Y8R A;  4APL A;  5CP9 A;  4R1B A;  2YIO A; 
#chains in the Genus database with same CATH topology
 3ERB A;  1OJV A;  1O9A A;  4AYM A;  3WSX A;  2EC3 A;  2UWN A;  1VVD A;  2MCY A;  1GMN A;  1NK1 A;  1TPM A;  1SS2 A;  4WJG 2;  3SP8 A;  4PO7 A;  1OJY A;  1OK9 A;  2CG6 A;  3FGR A;  3ZRZ A;  1H04 P;  1BHT A;  2Y8S A;  2IZ3 A;  4DJZ A;  1QGB A;  4YNX A;  2J8J A;  2XRD A;  1W8K A;  1TPG A;  5DN4 A;  4BWC A;  5HYT B;  4AYE A;  5CT1 A;  5HYP A;  1HFI A;  3VWO A;  3HN4 A;  2F83 A;  1G4G A;  4Z09 A;  4UAO A;  2RLQ A;  2G7I A;  3EJH A;  2Z8W A;  3SRJ A;  2I2L A;  2JGX A;  1E88 A;  4LOS A;  3CAL A;  4DUR A;  1CKL A;  1Z92 B;  1RLH A;  1ZJK A;  2LL4 M;  4UV6 A;  2JGW A;  4Z0E A;  4APM A;  3SRI A;  1FBR A;  5HYU B;  2RL0 A;  2Y8R A;  4APL A;  5EOK A;  1E8B A;  2YRA A;  2XRB A;  4KKD A;  5FO8 C;  5CT2 A;  5DN5 A;  3FGT A;  1HCC A;  1MD8 A;  3RJ3 D;  4R19 A;  2XQW C;  1UOT P;  4J38 B;  2O39 C;  1MD7 A;  1QUB A;  4IGD A;  3HMR A;  3F6K A;  2XWB F;  1VVC A;  2RKZ A;  3MQL A;  2Y8T A;  2Z8V A;  3HMS A;  1YXE A;  2QY0 A;  4R1A A;  1OK2 A;  1I8N A;  3O8E B;  1HFH A;  1GKG A;  1Z40 A;  2KRI A;  3ZWZ A;  1GHQ B;  1SRZ A;  5CP9 A;  4FXG G;  4C16 A;  4F4O C;  4R1C A;  2ERJ A;  1GP9 A;  3R62 A;  3IU3 I;  4MUC A;  2W80 A;  2CG7 A;  2J8L A;  5CT3 A;  2YIP A;  5EOD A;  3KZJ A;  2RKY A;  1GMO A;  5CS9 A;  4A5W B;  4JHS A;  1PPQ A;  2V8E A;  4AYI A;  2B5I D;  2YBY A;  4LOT A;  5CS1 A;  3K3T A;  2KMS A;  2KL5 A;  2JRA A;  4Z0F A;  5COE A;  3HMT A;  4IUA A;  4YIV A;  2CKU A;  2QJ2 A;  1G4F A;  2ZYC A;  3GOV A;  2QJ4 A;  1U5M A;  3NFP I;  4Z0D A;  3ZD1 A;  3WSY A;  2YIL A;  2IZ4 A;  4B2R A;  1HKY A;  1OJW A;  3CI0 J;  5CS5 A;  3INB C;  5CS3 A;  3ZD2 A;  3L89 M;  2A55 A;  2Q8B A;  4R1B A;  3GXE A;  2YIO A;  4AYD A;  3IX0 A;  4PZ5 A;  3MKP A;  4B2S A;  2RLP A;  3ZLE A;  1GPZ A;  3M7P A;  3OED C;  2XWJ I;  4CSY A;  2HGF A;  4N7E A;  5CSQ A;  1H2Q P;  5I0Q B;  1GKN A;  2BZM A;  2LOJ A;  4K12 A;  3KXV A;  5JPM G;  1E5G A;  2Q8A A;  1NWV A;  3OXU D;  3SW0 X;  4ZH1 D;  2X2Z A;  4ONT D;  3ZLD A;  2WII C;  3TVJ A;  1LY2 A;  5I25 A;  4MSL A;  4A5T S;  1OK3 A;  5HZP B;  1H2P P;  2K13 X;  2EHF A;  1Q3X A;  1C1Z A;  4YIZ A;  1ELV A;  1QO6 A;  3OP8 A;  1W81 A;  2W81 A;  1OK1 A;  2MCZ A;  1TPN A;  2LL3 A;  3NJA A;  3T5O A;  1H03 P; 
#chains in the Genus database with same CATH homology
 1GMN A;  3WSX A;  1NK1 A;  3SP8 A;  4PO7 A;  3FGR A;  1BHT A;  2Y8S A;  2J8J A;  1W8K A;  5CT1 A;  4BWC A;  3HN4 A;  2F83 A;  4Z09 A;  4UAO A;  2Z8W A;  3SRJ A;  2I2L A;  4DUR A;  2LL4 M;  4UV6 A;  4Z0E A;  4APM A;  3SRI A;  5EOK A;  2Y8R A;  4APL A;  5CT2 A;  3FGT A;  4R19 A;  3HMR A;  3F6K A;  2Y8T A;  2Z8V A;  3HMS A;  1YXE A;  4R1A A;  1I8N A;  1Z40 A;  3ZWZ A;  5CP9 A;  4R1C A;  1GP9 A;  2J8L A;  5CT3 A;  2YIP A;  5EOD A;  1GMO A;  5CS9 A;  5CS1 A;  2KL5 A;  4Z0F A;  5COE A;  3HMT A;  4IUA A;  4YIV A;  2QJ2 A;  2QJ4 A;  4Z0D A;  3WSY A;  2YIL A;  1HKY A;  5CS5 A;  5CS3 A;  2Q8B A;  4R1B A;  2YIO A;  3MKP A;  3ZLE A;  2HGF A;  4N7E A;  5CSQ A;  2Q8A A;  2X2Z A;  3ZLD A;  5I25 A;  4MSL A;  4A5T S;  2K13 X;  4YIZ A;  1W81 A;  2LL3 A;  3NJA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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