4YIZA

Crystal structure of engineered tgama1 lacking the dii loop in complex with an eimeria tenella ron2d3 peptide
Total Genus 102

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
102
sequence length
399
structure length
392
Chain Sequence
SGNPFQANVEMKTFMERFNLTHHHQSGIYVDLGQDKEVDGTLYREPAGLCPIWGKHIELQQPDRPPYRNNFLEDVPTEKEYKQSGNPLPGGFNLNFVTPSGQRISPFPMELLEKNSNIKASTDLGRCAEFAFKTVAMDKNNKATKYRYPFVYDSKKRLCHILYVSMQLMEGKKYCSVKGEPPDLTWYCFKPRKSVTENHHLIYGSAYVGENPDAFISKCPNQALRGYRFGVWKKGRCLDYTELTDTVIERVESKAQCWVKTFENDGVASDQPDQPHSGGVGRNYGFYYVDTTGEGKCALSDQVPDCLVSDSAAVSYTAAGSLSEETPNFIIPSNPSVTPPTPETALQCTADKFPDSFGACDVQACKRQKTSCVGGQIQSTSVDCTADEQNEC

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title An Extended Surface Loop on Toxoplasma gondii Apical Membrane Antigen 1 (AMA1) Governs Ligand Binding Selectivity.
pubmed doi rcsb
molecule tags Immune system
source organism Toxoplasma gondii me49
molecule keywords Apical membrane antigen AMA1
total genus 102
structure length 392
sequence length 399
chains with identical sequence C, E
ec nomenclature
pdb deposition date 2015-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02430 AMA-1 Apical membrane antigen 1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.70 Mainly Beta Ribbon Complement Module; domain 1 Complement Module; domain 1 4yizA03
3.50.4.30 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 4yizA01
2X2ZA 3ZLDA 4APLA 4YIVA 2Y8SA 2Y8RA 4YIZA 2Y8TA 3ZLEA
chains in the Genus database with same CATH superfamily
4R1AA 3INBC 3SRJA 2W81A 2EHFA 2RKYA 4KKDA 4R1BA 5JPMG 2CG7A 2RLQA 2Z8VA 4PZ5A 4MSLA 2Y8TA 1O9AA 3NJAA 4WJG2 1MD7A 3SRIA 2F83A 1LY2A 1HFHA 1QGBA 2ERJA 1H04P 2RLPA 2ZYCA 1OK9A 3OEDC 1I8NA 2K13X 5CS5A 5EOKA 4A5TS 3OP8A 2XWJI 5CS9A 4ONTD 4AYDA 2RKZA 1OJVA 1PPQA 1UOTP 2EC3A 3OXUD 1NWVA 1G4FA 4LOSA 3HMSA 4FXGG 4AYMA 2XRBA 4Z0FA 4Z0EA 3HMRA 2MCZA 3HN4A 5EODA 4YIVA 3ZLEA 3KZJA 3ERBA 5FO8C 1OJWA 4F4OC 1GMNA 5CS1A 2KRIA 3FGTA 1ELVA 4J38B 2LL3A 3HMTA 4UV6A 3EJHA 1HKYA 3KXVA 1Z92B 3VWOA 2YIPA 5HYUB 2A55A 1HFIA 3GOVA 4LOTA 1H2PP 1OK3A 5DN4A 3RJ3D 4R1CA 1VVDA 2Y8RA 5I0QB 1E88A 5CS3A 1H2QP 2CKUA 4Z09A 2V8EA 2B5ID 1FBRA 1VVCA 3O8EB 1GPZA 1GKNA 2QJ4A 2Q8AA 2KL5A 1E8BA 4CSYA 2J8JA 3MKPA 5COEA 1H03P 2LL4M 2Y8SA 4IUAA 5CT3A 1ZJKA 2QJ2A 1G4GA 2UWNA 3NFPI 1NK1A 1C1ZA 1GMOA 2LOJA 2XWBF 2X2ZA 3ZWZA 1OJYA 1OK2A 4APLA 3M7PA 1W8KA 5I25A 4JHSA 2G7IA 1TPMA 4DJZA 1E5GA 3K3TA 4YIZA 3F6KA 4UAOA 2XQWC 2RL0A 5CT2A 2YILA 4DURA 1GHQB 2MCYA 3L89M 4BWCA 3CI0J 2WIIC 1W81A 3R62A 3ZD1A 1GP9A 2Q8BA 2JRAA 1Q3XA 1TPNA 1MD8A 2XRDA 5DN5A 2IZ3A 3T5OA 1U5MA 5CT1A 4B2SA 3FGRA 2I2LA 3MQLA 5CP9A 3ZD2A 3IX0A 3TVJA 4R19A 3CALA 4AYEA 2HGFA 2YBYA 1QUBA 1SRZA 2YRAA 3ZLDA 2QY0A 1SS2A 4A5WB 2YIOA 2JGXA 3SW0X 4IGDA 5HYPA 4MUCA 5HYTB 4K12A 1CKLA 2W80A 1RLHA 3ZRZA 5HZPB 2J8LA 3WSXA 3IU3I 4AYIA 1HCCA 4APMA 1OK1A 2KMSA 4PO7A 4C16A 5CSQA 2IZ4A 1QO6A 2CG6A 1GKGA 2JGWA 4B2RA 1TPGA 4YNXA 1YXEA 1BHTA 3WSYA 4ZH1D 2Z8WA 4N7EA 2BZMA 3GXEA 3SP8A 4Z0DA 2O39C 1Z40A
chains in the Genus database with same CATH topology
4R1AA 3SRJA 4R1BA 2Z8VA 4MSLA 2Y8TA 3NJAA 3SRIA 2F83A 5EOKA 1I8NA 2K13X 4A5TS 5CS5A 5CS9A 3HMSA 4Z0FA 4Z0EA 3HMRA 3HN4A 5EODA 4YIVA 3ZLEA 1GMNA 5CS1A 3FGTA 3HMTA 2LL3A 4UV6A 1HKYA 2YIPA 4R1CA 4Z09A 5CS3A 2Y8RA 2QJ4A 2Q8AA 2KL5A 2J8JA 3MKPA 5COEA 2LL4M 2Y8SA 4IUAA 5CT3A 2QJ2A 1NK1A 1GMOA 2X2ZA 3ZWZA 4APLA 1W8KA 5I25A 4YIZA 3F6KA 4UAOA 5CT2A 2YILA 4DURA 1W81A 4BWCA 1GP9A 2Q8BA 5CT1A 3FGRA 2I2LA 5CP9A 4R19A 2HGFA 3ZLDA 2YIOA 2J8LA 3WSXA 4APMA 4PO7A 5CSQA 1YXEA 1BHTA 3WSYA 2Z8WA 4N7EA 3SP8A 4Z0DA 1Z40A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2X2Z A;  3ZLD A;  4APL A;  4YIV A;  2Y8S A;  2Y8R A;  4YIZ A;  2Y8T A;  3ZLE A; 
#chains in the Genus database with same CATH topology
 4R1A A;  3INB C;  3SRJ A;  2W81 A;  2EHF A;  2RKY A;  4KKD A;  4R1B A;  5JPM G;  2CG7 A;  2RLQ A;  2Z8V A;  4PZ5 A;  4MSL A;  2Y8T A;  1O9A A;  3NJA A;  4WJG 2;  1MD7 A;  3SRI A;  2F83 A;  1LY2 A;  1HFH A;  1QGB A;  2ERJ A;  1H04 P;  2RLP A;  2ZYC A;  1OK9 A;  3OED C;  1I8N A;  2K13 X;  5CS5 A;  5EOK A;  4A5T S;  3OP8 A;  2XWJ I;  5CS9 A;  4ONT D;  4AYD A;  2RKZ A;  1OJV A;  1PPQ A;  1UOT P;  2EC3 A;  3OXU D;  1NWV A;  1G4F A;  4LOS A;  3HMS A;  4FXG G;  4AYM A;  2XRB A;  4Z0F A;  4Z0E A;  3HMR A;  2MCZ A;  3HN4 A;  5EOD A;  4YIV A;  3ZLE A;  3KZJ A;  3ERB A;  5FO8 C;  1OJW A;  4F4O C;  1GMN A;  5CS1 A;  2KRI A;  3FGT A;  1ELV A;  4J38 B;  2LL3 A;  3HMT A;  4UV6 A;  3EJH A;  1HKY A;  3KXV A;  1Z92 B;  3VWO A;  2YIP A;  5HYU B;  2A55 A;  1HFI A;  3GOV A;  4LOT A;  1H2P P;  1OK3 A;  5DN4 A;  3RJ3 D;  4R1C A;  1VVD A;  2Y8R A;  5I0Q B;  1E88 A;  5CS3 A;  1H2Q P;  2CKU A;  4Z09 A;  2V8E A;  2B5I D;  1FBR A;  1VVC A;  3O8E B;  1GPZ A;  1GKN A;  2QJ4 A;  2Q8A A;  2KL5 A;  1E8B A;  4CSY A;  2J8J A;  3MKP A;  5COE A;  1H03 P;  2LL4 M;  2Y8S A;  4IUA A;  5CT3 A;  1ZJK A;  2QJ2 A;  1G4G A;  2UWN A;  3NFP I;  1NK1 A;  1C1Z A;  1GMO A;  2LOJ A;  2XWB F;  2X2Z A;  3ZWZ A;  1OJY A;  1OK2 A;  4APL A;  3M7P A;  1W8K A;  5I25 A;  4JHS A;  2G7I A;  1TPM A;  4DJZ A;  1E5G A;  3K3T A;  4YIZ A;  3F6K A;  4UAO A;  2XQW C;  2RL0 A;  5CT2 A;  2YIL A;  4DUR A;  1GHQ B;  2MCY A;  3L89 M;  4BWC A;  3CI0 J;  2WII C;  1W81 A;  3R62 A;  3ZD1 A;  1GP9 A;  2Q8B A;  2JRA A;  1Q3X A;  1TPN A;  1MD8 A;  2XRD A;  5DN5 A;  2IZ3 A;  3T5O A;  1U5M A;  5CT1 A;  4B2S A;  3FGR A;  2I2L A;  3MQL A;  5CP9 A;  3ZD2 A;  3IX0 A;  3TVJ A;  4R19 A;  3CAL A;  4AYE A;  2HGF A;  2YBY A;  1QUB A;  1SRZ A;  2YRA A;  3ZLD A;  2QY0 A;  1SS2 A;  4A5W B;  2YIO A;  2JGX A;  3SW0 X;  4IGD A;  5HYP A;  4MUC A;  5HYT B;  4K12 A;  1CKL A;  2W80 A;  1RLH A;  3ZRZ A;  5HZP B;  2J8L A;  3WSX A;  3IU3 I;  4AYI A;  1HCC A;  4APM A;  1OK1 A;  2KMS A;  4PO7 A;  4C16 A;  5CSQ A;  2IZ4 A;  1QO6 A;  2CG6 A;  1GKG A;  2JGW A;  4B2R A;  1TPG A;  4YNX A;  1YXE A;  1BHT A;  3WSY A;  4ZH1 D;  2Z8W A;  4N7E A;  2BZM A;  3GXE A;  3SP8 A;  4Z0D A;  2O39 C;  1Z40 A; 
#chains in the Genus database with same CATH homology
 4R1A A;  3SRJ A;  4R1B A;  2Z8V A;  4MSL A;  2Y8T A;  3NJA A;  3SRI A;  2F83 A;  5EOK A;  1I8N A;  2K13 X;  4A5T S;  5CS5 A;  5CS9 A;  3HMS A;  4Z0F A;  4Z0E A;  3HMR A;  3HN4 A;  5EOD A;  4YIV A;  3ZLE A;  1GMN A;  5CS1 A;  3FGT A;  3HMT A;  2LL3 A;  4UV6 A;  1HKY A;  2YIP A;  4R1C A;  4Z09 A;  5CS3 A;  2Y8R A;  2QJ4 A;  2Q8A A;  2KL5 A;  2J8J A;  3MKP A;  5COE A;  2LL4 M;  2Y8S A;  4IUA A;  5CT3 A;  2QJ2 A;  1NK1 A;  1GMO A;  2X2Z A;  3ZWZ A;  4APL A;  1W8K A;  5I25 A;  4YIZ A;  3F6K A;  4UAO A;  5CT2 A;  2YIL A;  4DUR A;  1W81 A;  4BWC A;  1GP9 A;  2Q8B A;  5CT1 A;  3FGR A;  2I2L A;  5CP9 A;  4R19 A;  2HGF A;  3ZLD A;  2YIO A;  2J8L A;  3WSX A;  4APM A;  4PO7 A;  5CSQ A;  1YXE A;  1BHT A;  3WSY A;  2Z8W A;  4N7E A;  3SP8 A;  4Z0D A;  1Z40 A; 
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similar chains in the pdb database (?% sequence similarity)

 
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