4YIZA

Crystal structure of engineered tgama1 lacking the dii loop in complex with an eimeria tenella ron2d3 peptide
Total Genus 102
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
102
sequence length
399
structure length
392
Chain Sequence
SGNPFQANVEMKTFMERFNLTHHHQSGIYVDLGQDKEVDGTLYREPAGLCPIWGKHIELQQPDRPPYRNNFLEDVPTEKEYKQSGNPLPGGFNLNFVTPSGQRISPFPMELLEKNSNIKASTDLGRCAEFAFKTVAMDKNNKATKYRYPFVYDSKKRLCHILYVSMQLMEGKKYCSVKGEPPDLTWYCFKPRKSVTENHHLIYGSAYVGENPDAFISKCPNQALRGYRFGVWKKGRCLDYTELTDTVIERVESKAQCWVKTFENDGVASDQPDQPHSGGVGRNYGFYYVDTTGEGKCALSDQVPDCLVSDSAAVSYTAAGSLSEETPNFIIPSNPSVTPPTPETALQCTADKFPDSFGACDVQACKRQKTSCVGGQIQSTSVDCTADEQNEC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title An Extended Surface Loop on Toxoplasma gondii Apical Membrane Antigen 1 (AMA1) Governs Ligand Binding Selectivity.
pubmed doi rcsb
molecule tags Immune system
source organism Toxoplasma gondii me49
molecule keywords Apical membrane antigen AMA1
total genus 102
structure length 392
sequence length 399
chains with identical sequence C, E
ec nomenclature
pdb deposition date 2015-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02430 AMA-1 Apical membrane antigen 1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.70 Mainly Beta Ribbon Complement Module; domain 1 Complement Module; domain 1 4yizA03
3.50.4.30 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 4yizA01
3ZLDA 4YIVA 3ZLEA 2X2ZA 2Y8TA 2Y8SA 2Y8RA 4APLA 4YIZA
chains in the Genus database with same CATH superfamily
2ERJA 4A5WB 4AYEA 5CP9A 1OJWA 2G7IA 5I0QB 1SS2A 4B2SA 4R1AA 4CSYA 3SP8A 3FGTA 2K13X 2J8LA 5I25A 4K12A 3MQLA 4R19A 1GMNA 3VWOA 2IZ3A 1H03P 2Q8AA 1RLHA 3SRIA 1NWVA 4C16A 2F83A 1MD7A 3IX0A 2WIIC 2I2LA 1VVCA 3GOVA 3ZD1A 2KMSA 3ZLDA 4LOTA 1W81A 2UWNA 4UAOA 5CS1A 1OK2A 1I8NA 1HCCA 4AYDA 5JPMG 1SRZA 2A55A 1VVDA 1PPQA 2CKUA 3ERBA 5DN4A 1QO6A 2RKZA 3GXEA 3ZLEA 5EOKA 2Y8SA 4UV6A 1ZJKA 2JGXA 2MCZA 1TPNA 3F6KA 1UOTP 2RKYA 4ZH1D 1YXEA 1H2PP 2EC3A 3O8EB 2XWJI 2O39C 3L89M 1W8KA 2KL5A 4KKDA 1H2QP 2YILA 2MCYA 4YIVA 5COEA 3WSXA 2X2ZA 1QUBA 3OEDC 4J38B 2LL4M 3CALA 5CS5A 3RJ3D 1G4FA 3M7PA 2YIOA 1H04P 3TVJA 5CT3A 5HYUB 3KXVA 2JGWA 1U5MA 3SW0X 4APLA 4Z09A 4Z0DA 2LL3A 3EJHA 1E8BA 2B5ID 5CT2A 1CKLA 5DN5A 1TPGA 1C1ZA 3FGRA 2EHFA 3MKPA 2XRDA 3NFPI 2W80A 1QGBA 2JRAA 5CT1A 1GP9A 4MSLA 2YBYA 2KRIA 2XWBF 1MD8A 2QY0A 2ZYCA 1HKYA 1HFIA 4LOSA 5CSQA 4DURA 1ELVA 3IU3I 4YNXA 2Z8VA 2Y8RA 2J8JA 3ZWZA 2Z8WA 4IGDA 1Z92B 2CG7A 2LOJA 3K3TA 1Q3XA 4DJZA 5HYTB 5HZPB 1FBRA 1GKNA 2XQWC 2RLQA 2QJ4A 3HMRA 3HMSA 3R62A 2V8EA 4R1BA 1TPMA 4A5TS 1GPZA 3CI0J 4PO7A 2Y8TA 1NK1A 3INBC 2IZ4A 3HMTA 5CS9A 3ZD2A 1O9AA 2XRBA 3OXUD 1E88A 1GKGA 1GMOA 4WJG2 3T5OA 1OK3A 1OK9A 5HYPA 4N7EA 2HGFA 2RL0A 2RLPA 3WSYA 4FXGG 3SRJA 4MUCA 4JHSA 1OK1A 5FO8C 3ZRZA 5CS3A 2YRAA 3NJAA 4APMA 1LY2A 5EODA 1Z40A 3OP8A 4F4OC 4IUAA 4BWCA 1HFHA 4ONTD 4AYMA 4B2RA 4PZ5A 2QJ2A 4Z0EA 1G4GA 4YIZA 3HN4A 2BZMA 1BHTA 2CG6A 2W81A 1GHQB 1E5GA 4AYIA 2Q8BA 1OJVA 4R1CA 2YIPA 3KZJA 4Z0FA 1OJYA
chains in the Genus database with same CATH topology
5CP9A 4R1AA 3SP8A 3FGTA 2K13X 2J8LA 5I25A 4R19A 1GMNA 2Q8AA 3SRIA 2F83A 2I2LA 3ZLDA 1W81A 4UAOA 5CS1A 1I8NA 3ZLEA 5EOKA 2Y8SA 4UV6A 3F6KA 1YXEA 2KL5A 1W8KA 2YILA 4YIVA 5COEA 3WSXA 2X2ZA 2LL4M 5CS5A 2YIOA 5CT3A 4Z09A 4APLA 4Z0DA 2LL3A 5CT2A 3FGRA 3MKPA 5CT1A 1GP9A 4MSLA 1HKYA 4DURA 5CSQA 2Z8VA 2Y8RA 2J8JA 3ZWZA 2Z8WA 2HGFA 3HMRA 5CS3A 2QJ4A 3HMSA 4A5TS 4R1BA 1NK1A 4PO7A 2Y8TA 3HMTA 5CS9A 1GMOA 4N7EA 3WSYA 3SRJA 3NJAA 4APMA 5EODA 1Z40A 4IUAA 4BWCA 2QJ2A 4Z0EA 4YIZA 3HN4A 1BHTA 2Q8BA 4R1CA 2YIPA 4Z0FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ZLD A;  4YIV A;  3ZLE A;  2X2Z A;  2Y8T A;  2Y8S A;  2Y8R A;  4APL A;  4YIZ A; 
#chains in the Genus database with same CATH topology
 2ERJ A;  4A5W B;  4AYE A;  5CP9 A;  1OJW A;  2G7I A;  5I0Q B;  1SS2 A;  4B2S A;  4R1A A;  4CSY A;  3SP8 A;  3FGT A;  2K13 X;  2J8L A;  5I25 A;  4K12 A;  3MQL A;  4R19 A;  1GMN A;  3VWO A;  2IZ3 A;  1H03 P;  2Q8A A;  1RLH A;  3SRI A;  1NWV A;  4C16 A;  2F83 A;  1MD7 A;  3IX0 A;  2WII C;  2I2L A;  1VVC A;  3GOV A;  3ZD1 A;  2KMS A;  3ZLD A;  4LOT A;  1W81 A;  2UWN A;  4UAO A;  5CS1 A;  1OK2 A;  1I8N A;  1HCC A;  4AYD A;  5JPM G;  1SRZ A;  2A55 A;  1VVD A;  1PPQ A;  2CKU A;  3ERB A;  5DN4 A;  1QO6 A;  2RKZ A;  3GXE A;  3ZLE A;  5EOK A;  2Y8S A;  4UV6 A;  1ZJK A;  2JGX A;  2MCZ A;  1TPN A;  3F6K A;  1UOT P;  2RKY A;  4ZH1 D;  1YXE A;  1H2P P;  2EC3 A;  3O8E B;  2XWJ I;  2O39 C;  3L89 M;  1W8K A;  2KL5 A;  4KKD A;  1H2Q P;  2YIL A;  2MCY A;  4YIV A;  5COE A;  3WSX A;  2X2Z A;  1QUB A;  3OED C;  4J38 B;  2LL4 M;  3CAL A;  5CS5 A;  3RJ3 D;  1G4F A;  3M7P A;  2YIO A;  1H04 P;  3TVJ A;  5CT3 A;  5HYU B;  3KXV A;  2JGW A;  1U5M A;  3SW0 X;  4APL A;  4Z09 A;  4Z0D A;  2LL3 A;  3EJH A;  1E8B A;  2B5I D;  5CT2 A;  1CKL A;  5DN5 A;  1TPG A;  1C1Z A;  3FGR A;  2EHF A;  3MKP A;  2XRD A;  3NFP I;  2W80 A;  1QGB A;  2JRA A;  5CT1 A;  1GP9 A;  4MSL A;  2YBY A;  2KRI A;  2XWB F;  1MD8 A;  2QY0 A;  2ZYC A;  1HKY A;  1HFI A;  4LOS A;  5CSQ A;  4DUR A;  1ELV A;  3IU3 I;  4YNX A;  2Z8V A;  2Y8R A;  2J8J A;  3ZWZ A;  2Z8W A;  4IGD A;  1Z92 B;  2CG7 A;  2LOJ A;  3K3T A;  1Q3X A;  4DJZ A;  5HYT B;  5HZP B;  1FBR A;  1GKN A;  2XQW C;  2RLQ A;  2QJ4 A;  3HMR A;  3HMS A;  3R62 A;  2V8E A;  4R1B A;  1TPM A;  4A5T S;  1GPZ A;  3CI0 J;  4PO7 A;  2Y8T A;  1NK1 A;  3INB C;  2IZ4 A;  3HMT A;  5CS9 A;  3ZD2 A;  1O9A A;  2XRB A;  3OXU D;  1E88 A;  1GKG A;  1GMO A;  4WJG 2;  3T5O A;  1OK3 A;  1OK9 A;  5HYP A;  4N7E A;  2HGF A;  2RL0 A;  2RLP A;  3WSY A;  4FXG G;  3SRJ A;  4MUC A;  4JHS A;  1OK1 A;  5FO8 C;  3ZRZ A;  5CS3 A;  2YRA A;  3NJA A;  4APM A;  1LY2 A;  5EOD A;  1Z40 A;  3OP8 A;  4F4O C;  4IUA A;  4BWC A;  1HFH A;  4ONT D;  4AYM A;  4B2R A;  4PZ5 A;  2QJ2 A;  4Z0E A;  1G4G A;  4YIZ A;  3HN4 A;  2BZM A;  1BHT A;  2CG6 A;  2W81 A;  1GHQ B;  1E5G A;  4AYI A;  2Q8B A;  1OJV A;  4R1C A;  2YIP A;  3KZJ A;  4Z0F A;  1OJY A; 
#chains in the Genus database with same CATH homology
 5CP9 A;  4R1A A;  3SP8 A;  3FGT A;  2K13 X;  2J8L A;  5I25 A;  4R19 A;  1GMN A;  2Q8A A;  3SRI A;  2F83 A;  2I2L A;  3ZLD A;  1W81 A;  4UAO A;  5CS1 A;  1I8N A;  3ZLE A;  5EOK A;  2Y8S A;  4UV6 A;  3F6K A;  1YXE A;  2KL5 A;  1W8K A;  2YIL A;  4YIV A;  5COE A;  3WSX A;  2X2Z A;  2LL4 M;  5CS5 A;  2YIO A;  5CT3 A;  4Z09 A;  4APL A;  4Z0D A;  2LL3 A;  5CT2 A;  3FGR A;  3MKP A;  5CT1 A;  1GP9 A;  4MSL A;  1HKY A;  4DUR A;  5CSQ A;  2Z8V A;  2Y8R A;  2J8J A;  3ZWZ A;  2Z8W A;  2HGF A;  3HMR A;  5CS3 A;  2QJ4 A;  3HMS A;  4A5T S;  4R1B A;  1NK1 A;  4PO7 A;  2Y8T A;  3HMT A;  5CS9 A;  1GMO A;  4N7E A;  3WSY A;  3SRJ A;  3NJA A;  4APM A;  5EOD A;  1Z40 A;  4IUA A;  4BWC A;  2QJ2 A;  4Z0E A;  4YIZ A;  3HN4 A;  1BHT A;  2Q8B A;  4R1C A;  2YIP A;  4Z0F A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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