2BR8A

Crystal structure of acetylcholine-binding protein (achbp) from aplysia californica in complex with an alpha-conotoxin pnia variant
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
205
structure length
205
Chain Sequence
QANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKVDSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGVTCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Nicotinic Acetylcholine Receptor Homolog Achbp in Complex with an Alpha-Conotoxin Pnia Variant
pubmed doi rcsb
molecule tags Receptor/inhibitor
source organism Aplysia californica
molecule keywords SOLUBLE ACETYLCHOLINE RECEPTOR
total genus 45
structure length 205
sequence length 205
chains with identical sequence B, C, D, E
ec nomenclature
pdb deposition date 2005-05-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 2br8A00
3UUBA 2XYTA 3JADA 2UZ6A 2BYNA 3U8LA 1UV6A 3WIPA 4HFCA 2WNJA 3EHZA 2WZYA 5FJVA 3TLVA 3TLUA 4BQTA 4F8HA 3RQUA 4AFTA 2BG9E 4NZBA 4QH1A 4FRRA 4PIRA 4QACA 5CFBA 3JAEA 5AFMB 5AFHA 4QABA 2XYSA 5AFJA 2BJ0A 3RHWA 4UM1A 3ZKRA 4A98A 4AFHA 4HFHA 4TNWA 2BYQA 5J5HA 5HEOA 3UU8A 1UX2A 3UU4A 3PEOA 3TLWA 2XQ6A 2BG9C 3U8JA 3EAMA 5TVCA 3WTNA 3SQ9A 4NPPA 4Z91A 2XQ5A 4ZR6A 4ZRUA 3WTLA 3WTHA 4ILCA 5AFKA 4HFDA 4HQPA 3UU5A 5HEUA 2PGZA 4HFEA 4HFBA 3U8KA 5HCJA 3UU3A 5HCMA 1UW6A 4AFGA 5BP0A 3T4MA 4XK9A 5AFLA 2PH9A 4IL9A 2BR7A 2BYRA 3RIFA 5J5FA 4D01A 2WN9A 5LXBA 5CO5A 5HEJA 4UM3P 3EI0A 3SH1A 3RQWA 2W8FA 3GUAA 3SQ6A 2BR8A 3RI5A 3WTIA 2XZ6A 2Y57A 5J0ZA 4TWHA 5LG3A 3TLTA 5HEGA 2Y54A 2YMEA 4B5DA 3P4WA 4TNVA 3UU6A 4TWFA 2YMDA 3JAFA 4ALXA 3ZDHA 5JMEA 5L4EA 5J5IA 2ZJUA 4HFIA 3PMZA 2W8GA 4A97A 2BYPA 3U8MA 2XNUA 2XNTA 4QH5A 2XQ3A 4LMKA 2X00A 4IREA 5L47A 4ZZBA 4WV9A 2WNLA 2VL0A 2XZ5A 4UY2A 2Y7YA 4ILBA 4ZJTA 2Y58A 4LMJA 5BRXA 2YN6A 3WTMA 4DBMA 4QAAA 5KZUA 2XQ8A 5HEHA 3RIAA 4EZ1A 4UM3A 3P50A 4X5TA 2XQAA 1I9BA 4ZK4A 3IGQA 3C79A 5IUXA 3ZDGA 2WNCA 2QC1B 4COFA 5SYOA 4XHEA 2XQ7A 4IL4A 2ZJVA 4UM3S 5J5GA 2YOEA 4ZK1A 2YKSA 2BG9B 3SIOA 3TLSA 4UXUA 2X00D 4ZJSA 3LSVA 3UQ7A 4QH4A 5AFNA 4ZZCA 5KE4A 3UQ4A 3WTJA 2XNVA 2XQ9A 4ILAA 4LMLA 2C9TA 5L4HA 4BFQA 5AINA 4Z90A 2XQ4A 3C84A 3WTOA 2BG9A 4TWDA 5BW2A 3WTKA 2BYSA 2Y56A 5AFMA 3U8NA
chains in the Genus database with same CATH superfamily
3UUBA 2XYTA 3JADA 2UZ6A 2BYNA 3U8LA 1UV6A 3WIPA 4HFCA 2WNJA 3EHZA 2WZYA 5FJVA 3TLVA 3TLUA 4BQTA 4F8HA 3RQUA 4AFTA 2BG9E 4NZBA 4QH1A 4FRRA 4PIRA 4QACA 5CFBA 3JAEA 5AFMB 5AFHA 4QABA 2XYSA 5AFJA 2BJ0A 3RHWA 4UM1A 3ZKRA 4A98A 4AFHA 4HFHA 4TNWA 2BYQA 5J5HA 5HEOA 3UU8A 1UX2A 3UU4A 3PEOA 3TLWA 2XQ6A 2BG9C 3U8JA 3EAMA 5TVCA 3WTNA 3SQ9A 4NPPA 4Z91A 2XQ5A 4ZR6A 4ZRUA 3WTLA 3WTHA 4ILCA 5AFKA 4HFDA 4HQPA 3UU5A 5HEUA 2PGZA 4HFEA 4HFBA 3U8KA 5HCJA 3UU3A 5HCMA 1UW6A 4AFGA 5BP0A 3T4MA 4XK9A 5AFLA 2PH9A 4IL9A 2BR7A 2BYRA 3RIFA 5J5FA 4D01A 2WN9A 5LXBA 5CO5A 5HEJA 4UM3P 3EI0A 3SH1A 3RQWA 2W8FA 3GUAA 3SQ6A 2BR8A 3RI5A 3WTIA 2XZ6A 2Y57A 5J0ZA 4TWHA 5LG3A 3TLTA 5HEGA 2Y54A 2YMEA 4B5DA 3P4WA 4TNVA 3UU6A 4TWFA 2YMDA 3JAFA 4ALXA 3ZDHA 5JMEA 5L4EA 5J5IA 2ZJUA 4HFIA 3PMZA 2W8GA 4A97A 2BYPA 3U8MA 2XNUA 2XNTA 4QH5A 2XQ3A 4LMKA 2X00A 4IREA 5L47A 4ZZBA 4WV9A 2WNLA 2VL0A 2XZ5A 4UY2A 2Y7YA 4ILBA 4ZJTA 2Y58A 4LMJA 5BRXA 2YN6A 3WTMA 4DBMA 4QAAA 5KZUA 2XQ8A 5HEHA 3RIAA 4EZ1A 4UM3A 3P50A 4X5TA 2XQAA 1I9BA 4ZK4A 3IGQA 3C79A 5IUXA 3ZDGA 2WNCA 2QC1B 4COFA 5SYOA 4XHEA 2XQ7A 4IL4A 2ZJVA 4UM3S 5J5GA 2YOEA 4ZK1A 2YKSA 2BG9B 3SIOA 3TLSA 4UXUA 2X00D 4ZJSA 3LSVA 3UQ7A 4QH4A 5AFNA 4ZZCA 5KE4A 3UQ4A 3WTJA 2XNVA 2XQ9A 4ILAA 4LMLA 2C9TA 5L4HA 4BFQA 5AINA 4Z90A 2XQ4A 3C84A 3WTOA 2BG9A 4TWDA 5BW2A 3WTKA 2BYSA 2Y56A 5AFMA 3U8NA
chains in the Genus database with same CATH topology
3UUBA 2XYTA 3JADA 2UZ6A 2BYNA 3U8LA 1UV6A 3WIPA 4HFCA 2WNJA 3EHZA 2WZYA 5FJVA 3TLVA 3TLUA 4BQTA 4F8HA 3RQUA 4AFTA 2BG9E 4NZBA 4QH1A 4FRRA 4PIRA 4QACA 5CFBA 3JAEA 5AFMB 5AFHA 4QABA 2XYSA 5AFJA 2BJ0A 3RHWA 4UM1A 3ZKRA 4A98A 4AFHA 4HFHA 4TNWA 2BYQA 5J5HA 5HEOA 3UU8A 1UX2A 3UU4A 3PEOA 3TLWA 2XQ6A 2BG9C 3U8JA 3EAMA 5TVCA 3WTNA 3SQ9A 4NPPA 4Z91A 2XQ5A 4ZR6A 4ZRUA 3WTLA 3WTHA 4ILCA 5AFKA 4HFDA 4HQPA 3UU5A 5HEUA 2PGZA 4HFEA 4HFBA 3U8KA 5HCJA 3UU3A 5HCMA 1UW6A 4AFGA 5BP0A 3T4MA 4XK9A 5AFLA 2PH9A 4IL9A 2BR7A 2BYRA 3RIFA 5J5FA 4D01A 2WN9A 5LXBA 5CO5A 5HEJA 4UM3P 3EI0A 3SH1A 3RQWA 2W8FA 3GUAA 3SQ6A 2BR8A 3RI5A 3WTIA 2XZ6A 2Y57A 5J0ZA 4TWHA 5LG3A 3TLTA 5HEGA 2Y54A 2YMEA 4B5DA 3P4WA 4TNVA 3UU6A 4TWFA 2YMDA 3JAFA 4ALXA 3ZDHA 5JMEA 5L4EA 5J5IA 2ZJUA 4HFIA 3PMZA 2W8GA 4A97A 2BYPA 3U8MA 2XNUA 2XNTA 4QH5A 2XQ3A 4LMKA 2X00A 4IREA 5L47A 4ZZBA 4WV9A 2WNLA 2VL0A 2XZ5A 4UY2A 2Y7YA 4ILBA 4ZJTA 2Y58A 4LMJA 5BRXA 2YN6A 3WTMA 4DBMA 4QAAA 5KZUA 2XQ8A 5HEHA 3RIAA 4EZ1A 4UM3A 3P50A 4X5TA 2XQAA 1I9BA 4ZK4A 3IGQA 3C79A 5IUXA 3ZDGA 2WNCA 2QC1B 4COFA 5SYOA 4XHEA 2XQ7A 4IL4A 2ZJVA 4UM3S 5J5GA 2YOEA 4ZK1A 2YKSA 2BG9B 3SIOA 3TLSA 4UXUA 2X00D 4ZJSA 3LSVA 3UQ7A 4QH4A 5AFNA 4ZZCA 5KE4A 3UQ4A 3WTJA 2XNVA 2XQ9A 4ILAA 4LMLA 2C9TA 5L4HA 4BFQA 5AINA 4Z90A 2XQ4A 3C84A 3WTOA 2BG9A 4TWDA 5BW2A 3WTKA 2BYSA 2Y56A 5AFMA 3U8NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3UUB A;  2XYT A;  3JAD A;  2UZ6 A;  2BYN A;  3U8L A;  1UV6 A;  3WIP A;  4HFC A;  2WNJ A;  3EHZ A;  2WZY A;  5FJV A;  3TLV A;  3TLU A;  4BQT A;  4F8H A;  3RQU A;  4AFT A;  2BG9 E;  4NZB A;  4QH1 A;  4FRR A;  4PIR A;  4QAC A;  5CFB A;  3JAE A;  5AFM B;  5AFH A;  4QAB A;  2XYS A;  5AFJ A;  2BJ0 A;  3RHW A;  4UM1 A;  3ZKR A;  4A98 A;  4AFH A;  4HFH A;  4TNW A;  2BYQ A;  5J5H A;  5HEO A;  3UU8 A;  1UX2 A;  3UU4 A;  3PEO A;  3TLW A;  2XQ6 A;  2BG9 C;  3U8J A;  3EAM A;  5TVC A;  3WTN A;  3SQ9 A;  4NPP A;  4Z91 A;  2XQ5 A;  4ZR6 A;  4ZRU A;  3WTL A;  3WTH A;  4ILC A;  5AFK A;  4HFD A;  4HQP A;  3UU5 A;  5HEU A;  2PGZ A;  4HFE A;  4HFB A;  3U8K A;  5HCJ A;  3UU3 A;  5HCM A;  1UW6 A;  4AFG A;  5BP0 A;  3T4M A;  4XK9 A;  5AFL A;  2PH9 A;  4IL9 A;  2BR7 A;  2BYR A;  3RIF A;  5J5F A;  4D01 A;  2WN9 A;  5LXB A;  5CO5 A;  5HEJ A;  4UM3 P;  3EI0 A;  3SH1 A;  3RQW A;  2W8F A;  3GUA A;  3SQ6 A;  2BR8 A;  3RI5 A;  3WTI A;  2XZ6 A;  2Y57 A;  5J0Z A;  4TWH A;  5LG3 A;  3TLT A;  5HEG A;  2Y54 A;  2YME A;  4B5D A;  3P4W A;  4TNV A;  3UU6 A;  4TWF A;  2YMD A;  3JAF A;  4ALX A;  3ZDH A;  5JME A;  5L4E A;  5J5I A;  2ZJU A;  4HFI A;  3PMZ A;  2W8G A;  4A97 A;  2BYP A;  3U8M A;  2XNU A;  2XNT A;  4QH5 A;  2XQ3 A;  4LMK A;  2X00 A;  4IRE A;  5L47 A;  4ZZB A;  4WV9 A;  2WNL A;  2VL0 A;  2XZ5 A;  4UY2 A;  2Y7Y A;  4ILB A;  4ZJT A;  2Y58 A;  4LMJ A;  5BRX A;  2YN6 A;  3WTM A;  4DBM A;  4QAA A;  5KZU A;  2XQ8 A;  5HEH A;  3RIA A;  4EZ1 A;  4UM3 A;  3P50 A;  4X5T A;  2XQA A;  1I9B A;  4ZK4 A;  3IGQ A;  3C79 A;  5IUX A;  3ZDG A;  2WNC A;  2QC1 B;  4COF A;  5SYO A;  4XHE A;  2XQ7 A;  4IL4 A;  2ZJV A;  4UM3 S;  5J5G A;  2YOE A;  4ZK1 A;  2YKS A;  2BG9 B;  3SIO A;  3TLS A;  4UXU A;  2X00 D;  4ZJS A;  3LSV A;  3UQ7 A;  4QH4 A;  5AFN A;  4ZZC A;  5KE4 A;  3UQ4 A;  3WTJ A;  2XNV A;  2XQ9 A;  4ILA A;  4LML A;  2C9T A;  5L4H A;  4BFQ A;  5AIN A;  4Z90 A;  2XQ4 A;  3C84 A;  3WTO A;  2BG9 A;  4TWD A;  5BW2 A;  3WTK A;  2BYS A;  2Y56 A;  5AFM A;  3U8N A; 
#chains in the Genus database with same CATH topology
 3UUB A;  2XYT A;  3JAD A;  2UZ6 A;  2BYN A;  3U8L A;  1UV6 A;  3WIP A;  4HFC A;  2WNJ A;  3EHZ A;  2WZY A;  5FJV A;  3TLV A;  3TLU A;  4BQT A;  4F8H A;  3RQU A;  4AFT A;  2BG9 E;  4NZB A;  4QH1 A;  4FRR A;  4PIR A;  4QAC A;  5CFB A;  3JAE A;  5AFM B;  5AFH A;  4QAB A;  2XYS A;  5AFJ A;  2BJ0 A;  3RHW A;  4UM1 A;  3ZKR A;  4A98 A;  4AFH A;  4HFH A;  4TNW A;  2BYQ A;  5J5H A;  5HEO A;  3UU8 A;  1UX2 A;  3UU4 A;  3PEO A;  3TLW A;  2XQ6 A;  2BG9 C;  3U8J A;  3EAM A;  5TVC A;  3WTN A;  3SQ9 A;  4NPP A;  4Z91 A;  2XQ5 A;  4ZR6 A;  4ZRU A;  3WTL A;  3WTH A;  4ILC A;  5AFK A;  4HFD A;  4HQP A;  3UU5 A;  5HEU A;  2PGZ A;  4HFE A;  4HFB A;  3U8K A;  5HCJ A;  3UU3 A;  5HCM A;  1UW6 A;  4AFG A;  5BP0 A;  3T4M A;  4XK9 A;  5AFL A;  2PH9 A;  4IL9 A;  2BR7 A;  2BYR A;  3RIF A;  5J5F A;  4D01 A;  2WN9 A;  5LXB A;  5CO5 A;  5HEJ A;  4UM3 P;  3EI0 A;  3SH1 A;  3RQW A;  2W8F A;  3GUA A;  3SQ6 A;  2BR8 A;  3RI5 A;  3WTI A;  2XZ6 A;  2Y57 A;  5J0Z A;  4TWH A;  5LG3 A;  3TLT A;  5HEG A;  2Y54 A;  2YME A;  4B5D A;  3P4W A;  4TNV A;  3UU6 A;  4TWF A;  2YMD A;  3JAF A;  4ALX A;  3ZDH A;  5JME A;  5L4E A;  5J5I A;  2ZJU A;  4HFI A;  3PMZ A;  2W8G A;  4A97 A;  2BYP A;  3U8M A;  2XNU A;  2XNT A;  4QH5 A;  2XQ3 A;  4LMK A;  2X00 A;  4IRE A;  5L47 A;  4ZZB A;  4WV9 A;  2WNL A;  2VL0 A;  2XZ5 A;  4UY2 A;  2Y7Y A;  4ILB A;  4ZJT A;  2Y58 A;  4LMJ A;  5BRX A;  2YN6 A;  3WTM A;  4DBM A;  4QAA A;  5KZU A;  2XQ8 A;  5HEH A;  3RIA A;  4EZ1 A;  4UM3 A;  3P50 A;  4X5T A;  2XQA A;  1I9B A;  4ZK4 A;  3IGQ A;  3C79 A;  5IUX A;  3ZDG A;  2WNC A;  2QC1 B;  4COF A;  5SYO A;  4XHE A;  2XQ7 A;  4IL4 A;  2ZJV A;  4UM3 S;  5J5G A;  2YOE A;  4ZK1 A;  2YKS A;  2BG9 B;  3SIO A;  3TLS A;  4UXU A;  2X00 D;  4ZJS A;  3LSV A;  3UQ7 A;  4QH4 A;  5AFN A;  4ZZC A;  5KE4 A;  3UQ4 A;  3WTJ A;  2XNV A;  2XQ9 A;  4ILA A;  4LML A;  2C9T A;  5L4H A;  4BFQ A;  5AIN A;  4Z90 A;  2XQ4 A;  3C84 A;  3WTO A;  2BG9 A;  4TWD A;  5BW2 A;  3WTK A;  2BYS A;  2Y56 A;  5AFM A;  3U8N A; 
#chains in the Genus database with same CATH homology
 3UUB A;  2XYT A;  3JAD A;  2UZ6 A;  2BYN A;  3U8L A;  1UV6 A;  3WIP A;  4HFC A;  2WNJ A;  3EHZ A;  2WZY A;  5FJV A;  3TLV A;  3TLU A;  4BQT A;  4F8H A;  3RQU A;  4AFT A;  2BG9 E;  4NZB A;  4QH1 A;  4FRR A;  4PIR A;  4QAC A;  5CFB A;  3JAE A;  5AFM B;  5AFH A;  4QAB A;  2XYS A;  5AFJ A;  2BJ0 A;  3RHW A;  4UM1 A;  3ZKR A;  4A98 A;  4AFH A;  4HFH A;  4TNW A;  2BYQ A;  5J5H A;  5HEO A;  3UU8 A;  1UX2 A;  3UU4 A;  3PEO A;  3TLW A;  2XQ6 A;  2BG9 C;  3U8J A;  3EAM A;  5TVC A;  3WTN A;  3SQ9 A;  4NPP A;  4Z91 A;  2XQ5 A;  4ZR6 A;  4ZRU A;  3WTL A;  3WTH A;  4ILC A;  5AFK A;  4HFD A;  4HQP A;  3UU5 A;  5HEU A;  2PGZ A;  4HFE A;  4HFB A;  3U8K A;  5HCJ A;  3UU3 A;  5HCM A;  1UW6 A;  4AFG A;  5BP0 A;  3T4M A;  4XK9 A;  5AFL A;  2PH9 A;  4IL9 A;  2BR7 A;  2BYR A;  3RIF A;  5J5F A;  4D01 A;  2WN9 A;  5LXB A;  5CO5 A;  5HEJ A;  4UM3 P;  3EI0 A;  3SH1 A;  3RQW A;  2W8F A;  3GUA A;  3SQ6 A;  2BR8 A;  3RI5 A;  3WTI A;  2XZ6 A;  2Y57 A;  5J0Z A;  4TWH A;  5LG3 A;  3TLT A;  5HEG A;  2Y54 A;  2YME A;  4B5D A;  3P4W A;  4TNV A;  3UU6 A;  4TWF A;  2YMD A;  3JAF A;  4ALX A;  3ZDH A;  5JME A;  5L4E A;  5J5I A;  2ZJU A;  4HFI A;  3PMZ A;  2W8G A;  4A97 A;  2BYP A;  3U8M A;  2XNU A;  2XNT A;  4QH5 A;  2XQ3 A;  4LMK A;  2X00 A;  4IRE A;  5L47 A;  4ZZB A;  4WV9 A;  2WNL A;  2VL0 A;  2XZ5 A;  4UY2 A;  2Y7Y A;  4ILB A;  4ZJT A;  2Y58 A;  4LMJ A;  5BRX A;  2YN6 A;  3WTM A;  4DBM A;  4QAA A;  5KZU A;  2XQ8 A;  5HEH A;  3RIA A;  4EZ1 A;  4UM3 A;  3P50 A;  4X5T A;  2XQA A;  1I9B A;  4ZK4 A;  3IGQ A;  3C79 A;  5IUX A;  3ZDG A;  2WNC A;  2QC1 B;  4COF A;  5SYO A;  4XHE A;  2XQ7 A;  4IL4 A;  2ZJV A;  4UM3 S;  5J5G A;  2YOE A;  4ZK1 A;  2YKS A;  2BG9 B;  3SIO A;  3TLS A;  4UXU A;  2X00 D;  4ZJS A;  3LSV A;  3UQ7 A;  4QH4 A;  5AFN A;  4ZZC A;  5KE4 A;  3UQ4 A;  3WTJ A;  2XNV A;  2XQ9 A;  4ILA A;  4LML A;  2C9T A;  5L4H A;  4BFQ A;  5AIN A;  4Z90 A;  2XQ4 A;  3C84 A;  3WTO A;  2BG9 A;  4TWD A;  5BW2 A;  3WTK A;  2BYS A;  2Y56 A;  5AFM A;  3U8N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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