2QC1B

Crystal structure of the extracellular domain of the nicotinic acetylcholine receptor 1 subunit bound to alpha-bungarotoxin at 1.9 a resolution
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
212
structure length
212
Chain Sequence
KSEHETRLEAKLFEDYSSVVRPVEDHREIVQVTVGLQLIQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDVVLYNNADGDFAIVKFTKVLLDYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTRTYDGSAVAINPESDQPDLSNFMESGEWVIKEARGWKHWVFYSCCPTTPYLDITYHFVMQRLP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the extracellular domain of nAChR alpha1 bound to alpha-bungarotoxin at 1.94 A resolution.
pubmed doi rcsb
molecule tags Protein binding
source organism Mus musculus
molecule keywords Alpha-bungarotoxin
total genus 46
structure length 212
sequence length 212
ec nomenclature
pdb deposition date 2007-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 2qc1B00
2BYSA 2WNLA 4FRRA 4ZK1A 4TWHA 4HFIA 3WTHA 5BRXA 3U8NA 4AFHA 4XK9A 3UU4A 2BYRA 5HEJA 5CO5A 3JAEA 4NZBA 5AFJA 3WTKA 3IGQA 4QH1A 3TLVA 2ZJUA 3SQ6A 5KZUA 1UW6A 3P50A 2XZ6A 4TNWA 4LMKA 3TLWA 3U8MA 3RI5A 2XQ8A 2WNCA 2XQAA 5J5IA 3WTMA 2XQ3A 3RQUA 4IL4A 5BP0A 4ILBA 5J5HA 2BG9C 2Y58A 2YN6A 5HCMA 4UM3S 5AFNA 4LMLA 2YKSA 5L4EA 3ZDHA 3TLSA 2XQ4A 3U8KA 2XNTA 3WTOA 3EAMA 3U8LA 2BYNA 2Y57A 2BYQA 4DBMA 2QC1B 2XQ9A 5HEHA 5FJVA 2XYTA 4QABA 4ZRUA 2YMDA 3P4WA 4IREA 5HEGA 5L4HA 3PEOA 4AFGA 3TLUA 4AFTA 5L47A 5J5GA 4QH4A 2YMEA 4ALXA 2W8FA 4UXUA 1UX2A 4ZJSA 5AINA 3ZKRA 5AFKA 3RHWA 3JADA 5J5FA 3EHZA 2PGZA 5HEOA 2BG9A 3U8JA 3UQ7A 3RIFA 3UU6A 2VL0A 5AFHA 3JAFA 4UM3P 4F8HA 2YOEA 4HFDA 2BG9E 2XQ7A 2XZ5A 4TWDA 4B5DA 4ILCA 2PH9A 3PMZA 4ZZBA 3WTJA 2Y54A 2XQ6A 5J0ZA 4ZZCA 4IL9A 4PIRA 2X00A 3SIOA 4QACA 2XQ5A 3LSVA 2BR7A 5LXBA 3T4MA 4QH5A 4ZJTA 5KE4A 4ZR6A 5BW2A 4Z90A 1UV6A 5CFBA 3WTLA 2C9TA 4COFA 4HFHA 4UM3A 3UUBA 3WTIA 4TNVA 5TVCA 3C84A 4HFBA 3WIPA 3ZDGA 2Y56A 3TLTA 4ZK4A 3UU5A 4HFCA 2XYSA 2WN9A 3UQ4A 3C79A 2ZJVA 4EZ1A 4D01A 2WZYA 4X5TA 3SH1A 5IUXA 4HFEA 2BG9B 5AFMA 4QAAA 2XNUA 4NPPA 1I9BA 5HCJA 2UZ6A 5SYOA 3UU3A 2X00D 4A98A 5LG3A 3RIAA 4Z91A 2BR8A 3WTNA 4XHEA 4HQPA 2XNVA 2BJ0A 4UY2A 3UU8A 5AFMB 2Y7YA 4ILAA 4UM1A 3RQWA 4BFQA 2BYPA 4TWFA 3SQ9A 4A97A 5AFLA 5JMEA 4BQTA 2WNJA 5HEUA 4WV9A 3EI0A 3GUAA 4LMJA 2W8GA
chains in the Genus database with same CATH superfamily
2BYSA 2WNLA 4FRRA 4ZK1A 4TWHA 4HFIA 3WTHA 5BRXA 3U8NA 4AFHA 4XK9A 3UU4A 2BYRA 5HEJA 5CO5A 3JAEA 4NZBA 5AFJA 3WTKA 3IGQA 4QH1A 3TLVA 2ZJUA 3SQ6A 5KZUA 1UW6A 3P50A 2XZ6A 4TNWA 4LMKA 3TLWA 3U8MA 3RI5A 2XQ8A 2WNCA 2XQAA 5J5IA 3WTMA 2XQ3A 3RQUA 4IL4A 5BP0A 4ILBA 5J5HA 2BG9C 2Y58A 2YN6A 5HCMA 4UM3S 5AFNA 4LMLA 2YKSA 5L4EA 3ZDHA 3TLSA 2XQ4A 3U8KA 2XNTA 3WTOA 3EAMA 3U8LA 2BYNA 2Y57A 2BYQA 4DBMA 2QC1B 2XQ9A 5HEHA 5FJVA 2XYTA 4QABA 4ZRUA 2YMDA 3P4WA 4IREA 5HEGA 5L4HA 3PEOA 4AFGA 3TLUA 4AFTA 5L47A 5J5GA 4QH4A 2YMEA 4ALXA 2W8FA 4UXUA 1UX2A 4ZJSA 5AINA 3ZKRA 5AFKA 3RHWA 3JADA 5J5FA 3EHZA 2PGZA 5HEOA 2BG9A 3U8JA 3UQ7A 3RIFA 3UU6A 2VL0A 5AFHA 3JAFA 4UM3P 4F8HA 2YOEA 4HFDA 2BG9E 2XQ7A 2XZ5A 4TWDA 4B5DA 4ILCA 2PH9A 3PMZA 4ZZBA 3WTJA 2Y54A 2XQ6A 5J0ZA 4ZZCA 4IL9A 4PIRA 2X00A 3SIOA 4QACA 2XQ5A 3LSVA 2BR7A 5LXBA 3T4MA 4QH5A 4ZJTA 5KE4A 4ZR6A 5BW2A 4Z90A 1UV6A 5CFBA 3WTLA 2C9TA 4COFA 4HFHA 4UM3A 3UUBA 3WTIA 4TNVA 5TVCA 3C84A 4HFBA 3WIPA 3ZDGA 2Y56A 3TLTA 4ZK4A 3UU5A 4HFCA 2XYSA 2WN9A 3UQ4A 3C79A 2ZJVA 4EZ1A 4D01A 2WZYA 4X5TA 3SH1A 5IUXA 4HFEA 2BG9B 5AFMA 4QAAA 2XNUA 4NPPA 1I9BA 5HCJA 2UZ6A 5SYOA 3UU3A 2X00D 4A98A 5LG3A 3RIAA 4Z91A 2BR8A 3WTNA 4XHEA 4HQPA 2XNVA 2BJ0A 4UY2A 3UU8A 5AFMB 2Y7YA 4ILAA 4UM1A 3RQWA 4BFQA 2BYPA 4TWFA 3SQ9A 4A97A 5AFLA 5JMEA 4BQTA 2WNJA 5HEUA 4WV9A 3EI0A 3GUAA 4LMJA 2W8GA
chains in the Genus database with same CATH topology
2BYSA 2WNLA 4FRRA 4ZK1A 4TWHA 4HFIA 3WTHA 5BRXA 3U8NA 4AFHA 4XK9A 3UU4A 2BYRA 5HEJA 5CO5A 3JAEA 4NZBA 5AFJA 3WTKA 3IGQA 4QH1A 3TLVA 2ZJUA 3SQ6A 5KZUA 1UW6A 3P50A 2XZ6A 4TNWA 4LMKA 3TLWA 3U8MA 3RI5A 2XQ8A 2WNCA 2XQAA 5J5IA 3WTMA 2XQ3A 3RQUA 4IL4A 5BP0A 4ILBA 5J5HA 2BG9C 2Y58A 2YN6A 5HCMA 4UM3S 5AFNA 4LMLA 2YKSA 5L4EA 3ZDHA 3TLSA 2XQ4A 3U8KA 2XNTA 3WTOA 3EAMA 3U8LA 2BYNA 2Y57A 2BYQA 4DBMA 2QC1B 2XQ9A 5HEHA 5FJVA 2XYTA 4QABA 4ZRUA 2YMDA 3P4WA 4IREA 5HEGA 5L4HA 3PEOA 4AFGA 3TLUA 4AFTA 5L47A 5J5GA 4QH4A 2YMEA 4ALXA 2W8FA 4UXUA 1UX2A 4ZJSA 5AINA 3ZKRA 5AFKA 3RHWA 3JADA 5J5FA 3EHZA 2PGZA 5HEOA 2BG9A 3U8JA 3UQ7A 3RIFA 3UU6A 2VL0A 5AFHA 3JAFA 4UM3P 4F8HA 2YOEA 4HFDA 2BG9E 2XQ7A 2XZ5A 4TWDA 4B5DA 4ILCA 2PH9A 3PMZA 4ZZBA 3WTJA 2Y54A 2XQ6A 5J0ZA 4ZZCA 4IL9A 4PIRA 2X00A 3SIOA 4QACA 2XQ5A 3LSVA 2BR7A 5LXBA 3T4MA 4QH5A 4ZJTA 5KE4A 4ZR6A 5BW2A 4Z90A 1UV6A 5CFBA 3WTLA 2C9TA 4COFA 4HFHA 4UM3A 3UUBA 3WTIA 4TNVA 5TVCA 3C84A 4HFBA 3WIPA 3ZDGA 2Y56A 3TLTA 4ZK4A 3UU5A 4HFCA 2XYSA 2WN9A 3UQ4A 3C79A 2ZJVA 4EZ1A 4D01A 2WZYA 4X5TA 3SH1A 5IUXA 4HFEA 2BG9B 5AFMA 4QAAA 2XNUA 4NPPA 1I9BA 5HCJA 2UZ6A 5SYOA 3UU3A 2X00D 4A98A 5LG3A 3RIAA 4Z91A 2BR8A 3WTNA 4XHEA 4HQPA 2XNVA 2BJ0A 4UY2A 3UU8A 5AFMB 2Y7YA 4ILAA 4UM1A 3RQWA 4BFQA 2BYPA 4TWFA 3SQ9A 4A97A 5AFLA 5JMEA 4BQTA 2WNJA 5HEUA 4WV9A 3EI0A 3GUAA 4LMJA 2W8GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BYS A;  2WNL A;  4FRR A;  4ZK1 A;  4TWH A;  4HFI A;  3WTH A;  5BRX A;  3U8N A;  4AFH A;  4XK9 A;  3UU4 A;  2BYR A;  5HEJ A;  5CO5 A;  3JAE A;  4NZB A;  5AFJ A;  3WTK A;  3IGQ A;  4QH1 A;  3TLV A;  2ZJU A;  3SQ6 A;  5KZU A;  1UW6 A;  3P50 A;  2XZ6 A;  4TNW A;  4LMK A;  3TLW A;  3U8M A;  3RI5 A;  2XQ8 A;  2WNC A;  2XQA A;  5J5I A;  3WTM A;  2XQ3 A;  3RQU A;  4IL4 A;  5BP0 A;  4ILB A;  5J5H A;  2BG9 C;  2Y58 A;  2YN6 A;  5HCM A;  4UM3 S;  5AFN A;  4LML A;  2YKS A;  5L4E A;  3ZDH A;  3TLS A;  2XQ4 A;  3U8K A;  2XNT A;  3WTO A;  3EAM A;  3U8L A;  2BYN A;  2Y57 A;  2BYQ A;  4DBM A;  2QC1 B;  2XQ9 A;  5HEH A;  5FJV A;  2XYT A;  4QAB A;  4ZRU A;  2YMD A;  3P4W A;  4IRE A;  5HEG A;  5L4H A;  3PEO A;  4AFG A;  3TLU A;  4AFT A;  5L47 A;  5J5G A;  4QH4 A;  2YME A;  4ALX A;  2W8F A;  4UXU A;  1UX2 A;  4ZJS A;  5AIN A;  3ZKR A;  5AFK A;  3RHW A;  3JAD A;  5J5F A;  3EHZ A;  2PGZ A;  5HEO A;  2BG9 A;  3U8J A;  3UQ7 A;  3RIF A;  3UU6 A;  2VL0 A;  5AFH A;  3JAF A;  4UM3 P;  4F8H A;  2YOE A;  4HFD A;  2BG9 E;  2XQ7 A;  2XZ5 A;  4TWD A;  4B5D A;  4ILC A;  2PH9 A;  3PMZ A;  4ZZB A;  3WTJ A;  2Y54 A;  2XQ6 A;  5J0Z A;  4ZZC A;  4IL9 A;  4PIR A;  2X00 A;  3SIO A;  4QAC A;  2XQ5 A;  3LSV A;  2BR7 A;  5LXB A;  3T4M A;  4QH5 A;  4ZJT A;  5KE4 A;  4ZR6 A;  5BW2 A;  4Z90 A;  1UV6 A;  5CFB A;  3WTL A;  2C9T A;  4COF A;  4HFH A;  4UM3 A;  3UUB A;  3WTI A;  4TNV A;  5TVC A;  3C84 A;  4HFB A;  3WIP A;  3ZDG A;  2Y56 A;  3TLT A;  4ZK4 A;  3UU5 A;  4HFC A;  2XYS A;  2WN9 A;  3UQ4 A;  3C79 A;  2ZJV A;  4EZ1 A;  4D01 A;  2WZY A;  4X5T A;  3SH1 A;  5IUX A;  4HFE A;  2BG9 B;  5AFM A;  4QAA A;  2XNU A;  4NPP A;  1I9B A;  5HCJ A;  2UZ6 A;  5SYO A;  3UU3 A;  2X00 D;  4A98 A;  5LG3 A;  3RIA A;  4Z91 A;  2BR8 A;  3WTN A;  4XHE A;  4HQP A;  2XNV A;  2BJ0 A;  4UY2 A;  3UU8 A;  5AFM B;  2Y7Y A;  4ILA A;  4UM1 A;  3RQW A;  4BFQ A;  2BYP A;  4TWF A;  3SQ9 A;  4A97 A;  5AFL A;  5JME A;  4BQT A;  2WNJ A;  5HEU A;  4WV9 A;  3EI0 A;  3GUA A;  4LMJ A;  2W8G A; 
#chains in the Genus database with same CATH topology
 2BYS A;  2WNL A;  4FRR A;  4ZK1 A;  4TWH A;  4HFI A;  3WTH A;  5BRX A;  3U8N A;  4AFH A;  4XK9 A;  3UU4 A;  2BYR A;  5HEJ A;  5CO5 A;  3JAE A;  4NZB A;  5AFJ A;  3WTK A;  3IGQ A;  4QH1 A;  3TLV A;  2ZJU A;  3SQ6 A;  5KZU A;  1UW6 A;  3P50 A;  2XZ6 A;  4TNW A;  4LMK A;  3TLW A;  3U8M A;  3RI5 A;  2XQ8 A;  2WNC A;  2XQA A;  5J5I A;  3WTM A;  2XQ3 A;  3RQU A;  4IL4 A;  5BP0 A;  4ILB A;  5J5H A;  2BG9 C;  2Y58 A;  2YN6 A;  5HCM A;  4UM3 S;  5AFN A;  4LML A;  2YKS A;  5L4E A;  3ZDH A;  3TLS A;  2XQ4 A;  3U8K A;  2XNT A;  3WTO A;  3EAM A;  3U8L A;  2BYN A;  2Y57 A;  2BYQ A;  4DBM A;  2QC1 B;  2XQ9 A;  5HEH A;  5FJV A;  2XYT A;  4QAB A;  4ZRU A;  2YMD A;  3P4W A;  4IRE A;  5HEG A;  5L4H A;  3PEO A;  4AFG A;  3TLU A;  4AFT A;  5L47 A;  5J5G A;  4QH4 A;  2YME A;  4ALX A;  2W8F A;  4UXU A;  1UX2 A;  4ZJS A;  5AIN A;  3ZKR A;  5AFK A;  3RHW A;  3JAD A;  5J5F A;  3EHZ A;  2PGZ A;  5HEO A;  2BG9 A;  3U8J A;  3UQ7 A;  3RIF A;  3UU6 A;  2VL0 A;  5AFH A;  3JAF A;  4UM3 P;  4F8H A;  2YOE A;  4HFD A;  2BG9 E;  2XQ7 A;  2XZ5 A;  4TWD A;  4B5D A;  4ILC A;  2PH9 A;  3PMZ A;  4ZZB A;  3WTJ A;  2Y54 A;  2XQ6 A;  5J0Z A;  4ZZC A;  4IL9 A;  4PIR A;  2X00 A;  3SIO A;  4QAC A;  2XQ5 A;  3LSV A;  2BR7 A;  5LXB A;  3T4M A;  4QH5 A;  4ZJT A;  5KE4 A;  4ZR6 A;  5BW2 A;  4Z90 A;  1UV6 A;  5CFB A;  3WTL A;  2C9T A;  4COF A;  4HFH A;  4UM3 A;  3UUB A;  3WTI A;  4TNV A;  5TVC A;  3C84 A;  4HFB A;  3WIP A;  3ZDG A;  2Y56 A;  3TLT A;  4ZK4 A;  3UU5 A;  4HFC A;  2XYS A;  2WN9 A;  3UQ4 A;  3C79 A;  2ZJV A;  4EZ1 A;  4D01 A;  2WZY A;  4X5T A;  3SH1 A;  5IUX A;  4HFE A;  2BG9 B;  5AFM A;  4QAA A;  2XNU A;  4NPP A;  1I9B A;  5HCJ A;  2UZ6 A;  5SYO A;  3UU3 A;  2X00 D;  4A98 A;  5LG3 A;  3RIA A;  4Z91 A;  2BR8 A;  3WTN A;  4XHE A;  4HQP A;  2XNV A;  2BJ0 A;  4UY2 A;  3UU8 A;  5AFM B;  2Y7Y A;  4ILA A;  4UM1 A;  3RQW A;  4BFQ A;  2BYP A;  4TWF A;  3SQ9 A;  4A97 A;  5AFL A;  5JME A;  4BQT A;  2WNJ A;  5HEU A;  4WV9 A;  3EI0 A;  3GUA A;  4LMJ A;  2W8G A; 
#chains in the Genus database with same CATH homology
 2BYS A;  2WNL A;  4FRR A;  4ZK1 A;  4TWH A;  4HFI A;  3WTH A;  5BRX A;  3U8N A;  4AFH A;  4XK9 A;  3UU4 A;  2BYR A;  5HEJ A;  5CO5 A;  3JAE A;  4NZB A;  5AFJ A;  3WTK A;  3IGQ A;  4QH1 A;  3TLV A;  2ZJU A;  3SQ6 A;  5KZU A;  1UW6 A;  3P50 A;  2XZ6 A;  4TNW A;  4LMK A;  3TLW A;  3U8M A;  3RI5 A;  2XQ8 A;  2WNC A;  2XQA A;  5J5I A;  3WTM A;  2XQ3 A;  3RQU A;  4IL4 A;  5BP0 A;  4ILB A;  5J5H A;  2BG9 C;  2Y58 A;  2YN6 A;  5HCM A;  4UM3 S;  5AFN A;  4LML A;  2YKS A;  5L4E A;  3ZDH A;  3TLS A;  2XQ4 A;  3U8K A;  2XNT A;  3WTO A;  3EAM A;  3U8L A;  2BYN A;  2Y57 A;  2BYQ A;  4DBM A;  2QC1 B;  2XQ9 A;  5HEH A;  5FJV A;  2XYT A;  4QAB A;  4ZRU A;  2YMD A;  3P4W A;  4IRE A;  5HEG A;  5L4H A;  3PEO A;  4AFG A;  3TLU A;  4AFT A;  5L47 A;  5J5G A;  4QH4 A;  2YME A;  4ALX A;  2W8F A;  4UXU A;  1UX2 A;  4ZJS A;  5AIN A;  3ZKR A;  5AFK A;  3RHW A;  3JAD A;  5J5F A;  3EHZ A;  2PGZ A;  5HEO A;  2BG9 A;  3U8J A;  3UQ7 A;  3RIF A;  3UU6 A;  2VL0 A;  5AFH A;  3JAF A;  4UM3 P;  4F8H A;  2YOE A;  4HFD A;  2BG9 E;  2XQ7 A;  2XZ5 A;  4TWD A;  4B5D A;  4ILC A;  2PH9 A;  3PMZ A;  4ZZB A;  3WTJ A;  2Y54 A;  2XQ6 A;  5J0Z A;  4ZZC A;  4IL9 A;  4PIR A;  2X00 A;  3SIO A;  4QAC A;  2XQ5 A;  3LSV A;  2BR7 A;  5LXB A;  3T4M A;  4QH5 A;  4ZJT A;  5KE4 A;  4ZR6 A;  5BW2 A;  4Z90 A;  1UV6 A;  5CFB A;  3WTL A;  2C9T A;  4COF A;  4HFH A;  4UM3 A;  3UUB A;  3WTI A;  4TNV A;  5TVC A;  3C84 A;  4HFB A;  3WIP A;  3ZDG A;  2Y56 A;  3TLT A;  4ZK4 A;  3UU5 A;  4HFC A;  2XYS A;  2WN9 A;  3UQ4 A;  3C79 A;  2ZJV A;  4EZ1 A;  4D01 A;  2WZY A;  4X5T A;  3SH1 A;  5IUX A;  4HFE A;  2BG9 B;  5AFM A;  4QAA A;  2XNU A;  4NPP A;  1I9B A;  5HCJ A;  2UZ6 A;  5SYO A;  3UU3 A;  2X00 D;  4A98 A;  5LG3 A;  3RIA A;  4Z91 A;  2BR8 A;  3WTN A;  4XHE A;  4HQP A;  2XNV A;  2BJ0 A;  4UY2 A;  3UU8 A;  5AFM B;  2Y7Y A;  4ILA A;  4UM1 A;  3RQW A;  4BFQ A;  2BYP A;  4TWF A;  3SQ9 A;  4A97 A;  5AFL A;  5JME A;  4BQT A;  2WNJ A;  5HEU A;  4WV9 A;  3EI0 A;  3GUA A;  4LMJ A;  2W8G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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