2WNCA

Crystal structure of aplysia achbp in complex with tropisetron
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
215
structure length
215
Chain Sequence
DDDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERRAG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal alpha7 nicotinic acetylcholine receptor.
pubmed doi rcsb
molecule keywords Soluble acetylcholine receptor
molecule tags Receptor
source organism Aplysia californica
total genus 53
structure length 215
sequence length 215
chains with identical sequence B, C, D, E
ec nomenclature
pdb deposition date 2009-07-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 2wncA00
3SH1A 2BG9C 3EHZA 2Y7YA 4ILAA 2Y58A 3P4WA 5BRXA 5HEOA 2XNUA 3ZKRA 4LMJA 2WZYA 4COFA 4TWDA 3WTHA 5LG3A 3RIAA 5BP0A 4HFEA 2X00D 4XK9A 5HEJA 3RI5A 3WTNA 5AFMB 1I9BA 4IREA 4UXUA 2X00A 5CFBA 2VL0A 2PGZA 3TLTA 3WTMA 5J5FA 2XYSA 2BG9B 4HQPA 3TLUA 3C84A 4HFIA 2BJ0A 5J5IA 3ZDGA 5AFMA 2BG9E 3WTLA 3SQ9A 3UU3A 4ZZCA 5L4EA 3TLVA 2XQ6A 3UUBA 5LXBA 5HCJA 3UQ7A 3RIFA 4A98A 4TNWA 2W8FA 4BFQA 3UU8A 4ILBA 2BG9A 2BYSA 2BYRA 4QH1A 4DBMA 4AFTA 4IL4A 4LMKA 4UM3P 2WNLA 4ZK4A 4ZJTA 2XQ7A 2YN6A 2XQ8A 3U8KA 3SQ6A 5L4HA 4LMLA 3WIPA 4ALXA 5TVCA 5HEGA 5J5HA 4QABA 1UW6A 4ZK1A 5AFNA 3LSVA 5KE4A 2YMEA 2YOEA 2XQAA 2Y54A 2Y56A 2BR8A 4UM1A 3JAFA 5AINA 2YKSA 2XZ6A 3UU4A 5J5GA 4XHEA 2BYNA 4HFDA 2UZ6A 2XYTA 4ZRUA 4ZJSA 3JADA 2XNTA 4HFBA 3GUAA 4X5TA 5AFHA 3WTKA 2PH9A 4ZR6A 4D01A 4F8HA 3IGQA 1UX2A 2XNVA 2XQ4A 5IUXA 3ZDHA 3EI0A 3P50A 3WTOA 4Z91A 2XZ5A 3TLSA 3T4MA 4QAAA 3TLWA 3U8NA 2YMDA 4IL9A 4QACA 4TWHA 2ZJUA 4EZ1A 4UM3A 5SYOA 5KZUA 3UQ4A 3PMZA 3SIOA 2XQ3A 4QH5A 4ZZBA 4UY2A 4UM3S 2XQ9A 5CO5A 3U8JA 3U8MA 2WN9A 4QH4A 5HEHA 5AFJA 2ZJVA 2XQ5A 3EAMA 4NZBA 4AFGA 5HCMA 4TWFA 5J0ZA 4FRRA 3U8LA 3WTIA 4Z90A 3WTJA 2WNJA 3RHWA 4A97A 5L47A 4NPPA 4PIRA 3JAEA 3C79A 4HFCA 2BYPA 2C9TA 4TNVA 2Y57A 2W8GA 5AFKA 3UU5A 5BW2A 3RQWA 2BYQA 4WV9A 1UV6A 4ILCA 4BQTA 5JMEA 2WNCA 4HFHA 3UU6A 4B5DA 3RQUA 3PEOA 5HEUA 5AFLA 2BR7A 4AFHA 5FJVA 2QC1B
chains in the Genus database with same CATH superfamily
3SH1A 2BG9C 3EHZA 2Y7YA 4ILAA 2Y58A 3P4WA 5BRXA 5HEOA 2XNUA 3ZKRA 4LMJA 2WZYA 4COFA 4TWDA 3WTHA 5LG3A 3RIAA 5BP0A 4HFEA 2X00D 4XK9A 5HEJA 3RI5A 3WTNA 5AFMB 1I9BA 4IREA 4UXUA 2X00A 5CFBA 2VL0A 2PGZA 3TLTA 3WTMA 5J5FA 2XYSA 2BG9B 4HQPA 3TLUA 3C84A 4HFIA 2BJ0A 5J5IA 3ZDGA 5AFMA 2BG9E 3WTLA 3SQ9A 3UU3A 4ZZCA 5L4EA 3TLVA 2XQ6A 3UUBA 5LXBA 5HCJA 3UQ7A 3RIFA 4A98A 4TNWA 2W8FA 4BFQA 3UU8A 4ILBA 2BG9A 2BYSA 2BYRA 4QH1A 4DBMA 4AFTA 4IL4A 4LMKA 4UM3P 2WNLA 4ZK4A 4ZJTA 2XQ7A 2YN6A 2XQ8A 3U8KA 3SQ6A 5L4HA 4LMLA 3WIPA 4ALXA 5TVCA 5HEGA 5J5HA 4QABA 1UW6A 4ZK1A 5AFNA 3LSVA 5KE4A 2YMEA 2YOEA 2XQAA 2Y54A 2Y56A 2BR8A 4UM1A 3JAFA 5AINA 2YKSA 2XZ6A 3UU4A 5J5GA 4XHEA 2BYNA 4HFDA 2UZ6A 2XYTA 4ZRUA 4ZJSA 3JADA 2XNTA 4HFBA 3GUAA 4X5TA 5AFHA 3WTKA 2PH9A 4ZR6A 4D01A 4F8HA 3IGQA 1UX2A 2XNVA 2XQ4A 5IUXA 3ZDHA 3EI0A 3P50A 3WTOA 4Z91A 2XZ5A 3TLSA 3T4MA 4QAAA 3TLWA 3U8NA 2YMDA 4IL9A 4QACA 4TWHA 2ZJUA 4EZ1A 4UM3A 5SYOA 5KZUA 3UQ4A 3PMZA 3SIOA 2XQ3A 4QH5A 4ZZBA 4UY2A 4UM3S 2XQ9A 5CO5A 3U8JA 3U8MA 2WN9A 4QH4A 5HEHA 5AFJA 2ZJVA 2XQ5A 3EAMA 4NZBA 4AFGA 5HCMA 4TWFA 5J0ZA 4FRRA 3U8LA 3WTIA 4Z90A 3WTJA 2WNJA 3RHWA 4A97A 5L47A 4NPPA 4PIRA 3JAEA 3C79A 4HFCA 2BYPA 2C9TA 4TNVA 2Y57A 2W8GA 5AFKA 3UU5A 5BW2A 3RQWA 2BYQA 4WV9A 1UV6A 4ILCA 4BQTA 5JMEA 2WNCA 4HFHA 3UU6A 4B5DA 3RQUA 3PEOA 5HEUA 5AFLA 2BR7A 4AFHA 5FJVA 2QC1B
chains in the Genus database with same CATH topology
3SH1A 2BG9C 3EHZA 2Y7YA 4ILAA 2Y58A 3P4WA 5BRXA 5HEOA 2XNUA 3ZKRA 4LMJA 2WZYA 4COFA 4TWDA 3WTHA 5LG3A 3RIAA 5BP0A 4HFEA 2X00D 4XK9A 5HEJA 3RI5A 3WTNA 5AFMB 1I9BA 4IREA 4UXUA 2X00A 5CFBA 2VL0A 2PGZA 3TLTA 3WTMA 5J5FA 2XYSA 2BG9B 4HQPA 3TLUA 3C84A 4HFIA 2BJ0A 5J5IA 3ZDGA 5AFMA 2BG9E 3WTLA 3SQ9A 3UU3A 4ZZCA 5L4EA 3TLVA 2XQ6A 3UUBA 5LXBA 5HCJA 3UQ7A 3RIFA 4A98A 4TNWA 2W8FA 4BFQA 3UU8A 4ILBA 2BG9A 2BYSA 2BYRA 4QH1A 4DBMA 4AFTA 4IL4A 4LMKA 4UM3P 2WNLA 4ZK4A 4ZJTA 2XQ7A 2YN6A 2XQ8A 3U8KA 3SQ6A 5L4HA 4LMLA 3WIPA 4ALXA 5TVCA 5HEGA 5J5HA 4QABA 1UW6A 4ZK1A 5AFNA 3LSVA 5KE4A 2YMEA 2YOEA 2XQAA 2Y54A 2Y56A 2BR8A 4UM1A 3JAFA 5AINA 2YKSA 2XZ6A 3UU4A 5J5GA 4XHEA 2BYNA 4HFDA 2UZ6A 2XYTA 4ZRUA 4ZJSA 3JADA 2XNTA 4HFBA 3GUAA 4X5TA 5AFHA 3WTKA 2PH9A 4ZR6A 4D01A 4F8HA 3IGQA 1UX2A 2XNVA 2XQ4A 5IUXA 3ZDHA 3EI0A 3P50A 3WTOA 4Z91A 2XZ5A 3TLSA 3T4MA 4QAAA 3TLWA 3U8NA 2YMDA 4IL9A 4QACA 4TWHA 2ZJUA 4EZ1A 4UM3A 5SYOA 5KZUA 3UQ4A 3PMZA 3SIOA 2XQ3A 4QH5A 4ZZBA 4UY2A 4UM3S 2XQ9A 5CO5A 3U8JA 3U8MA 2WN9A 4QH4A 5HEHA 5AFJA 2ZJVA 2XQ5A 3EAMA 4NZBA 4AFGA 5HCMA 4TWFA 5J0ZA 4FRRA 3U8LA 3WTIA 4Z90A 3WTJA 2WNJA 3RHWA 4A97A 5L47A 4NPPA 4PIRA 3JAEA 3C79A 4HFCA 2BYPA 2C9TA 4TNVA 2Y57A 2W8GA 5AFKA 3UU5A 5BW2A 3RQWA 2BYQA 4WV9A 1UV6A 4ILCA 4BQTA 5JMEA 2WNCA 4HFHA 3UU6A 4B5DA 3RQUA 3PEOA 5HEUA 5AFLA 2BR7A 4AFHA 5FJVA 2QC1B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SH1 A;  2BG9 C;  3EHZ A;  2Y7Y A;  4ILA A;  2Y58 A;  3P4W A;  5BRX A;  5HEO A;  2XNU A;  3ZKR A;  4LMJ A;  2WZY A;  4COF A;  4TWD A;  3WTH A;  5LG3 A;  3RIA A;  5BP0 A;  4HFE A;  2X00 D;  4XK9 A;  5HEJ A;  3RI5 A;  3WTN A;  5AFM B;  1I9B A;  4IRE A;  4UXU A;  2X00 A;  5CFB A;  2VL0 A;  2PGZ A;  3TLT A;  3WTM A;  5J5F A;  2XYS A;  2BG9 B;  4HQP A;  3TLU A;  3C84 A;  4HFI A;  2BJ0 A;  5J5I A;  3ZDG A;  5AFM A;  2BG9 E;  3WTL A;  3SQ9 A;  3UU3 A;  4ZZC A;  5L4E A;  3TLV A;  2XQ6 A;  3UUB A;  5LXB A;  5HCJ A;  3UQ7 A;  3RIF A;  4A98 A;  4TNW A;  2W8F A;  4BFQ A;  3UU8 A;  4ILB A;  2BG9 A;  2BYS A;  2BYR A;  4QH1 A;  4DBM A;  4AFT A;  4IL4 A;  4LMK A;  4UM3 P;  2WNL A;  4ZK4 A;  4ZJT A;  2XQ7 A;  2YN6 A;  2XQ8 A;  3U8K A;  3SQ6 A;  5L4H A;  4LML A;  3WIP A;  4ALX A;  5TVC A;  5HEG A;  5J5H A;  4QAB A;  1UW6 A;  4ZK1 A;  5AFN A;  3LSV A;  5KE4 A;  2YME A;  2YOE A;  2XQA A;  2Y54 A;  2Y56 A;  2BR8 A;  4UM1 A;  3JAF A;  5AIN A;  2YKS A;  2XZ6 A;  3UU4 A;  5J5G A;  4XHE A;  2BYN A;  4HFD A;  2UZ6 A;  2XYT A;  4ZRU A;  4ZJS A;  3JAD A;  2XNT A;  4HFB A;  3GUA A;  4X5T A;  5AFH A;  3WTK A;  2PH9 A;  4ZR6 A;  4D01 A;  4F8H A;  3IGQ A;  1UX2 A;  2XNV A;  2XQ4 A;  5IUX A;  3ZDH A;  3EI0 A;  3P50 A;  3WTO A;  4Z91 A;  2XZ5 A;  3TLS A;  3T4M A;  4QAA A;  3TLW A;  3U8N A;  2YMD A;  4IL9 A;  4QAC A;  4TWH A;  2ZJU A;  4EZ1 A;  4UM3 A;  5SYO A;  5KZU A;  3UQ4 A;  3PMZ A;  3SIO A;  2XQ3 A;  4QH5 A;  4ZZB A;  4UY2 A;  4UM3 S;  2XQ9 A;  5CO5 A;  3U8J A;  3U8M A;  2WN9 A;  4QH4 A;  5HEH A;  5AFJ A;  2ZJV A;  2XQ5 A;  3EAM A;  4NZB A;  4AFG A;  5HCM A;  4TWF A;  5J0Z A;  4FRR A;  3U8L A;  3WTI A;  4Z90 A;  3WTJ A;  2WNJ A;  3RHW A;  4A97 A;  5L47 A;  4NPP A;  4PIR A;  3JAE A;  3C79 A;  4HFC A;  2BYP A;  2C9T A;  4TNV A;  2Y57 A;  2W8G A;  5AFK A;  3UU5 A;  5BW2 A;  3RQW A;  2BYQ A;  4WV9 A;  1UV6 A;  4ILC A;  4BQT A;  5JME A;  2WNC A;  4HFH A;  3UU6 A;  4B5D A;  3RQU A;  3PEO A;  5HEU A;  5AFL A;  2BR7 A;  4AFH A;  5FJV A;  2QC1 B; 
#chains in the Genus database with same CATH topology
 3SH1 A;  2BG9 C;  3EHZ A;  2Y7Y A;  4ILA A;  2Y58 A;  3P4W A;  5BRX A;  5HEO A;  2XNU A;  3ZKR A;  4LMJ A;  2WZY A;  4COF A;  4TWD A;  3WTH A;  5LG3 A;  3RIA A;  5BP0 A;  4HFE A;  2X00 D;  4XK9 A;  5HEJ A;  3RI5 A;  3WTN A;  5AFM B;  1I9B A;  4IRE A;  4UXU A;  2X00 A;  5CFB A;  2VL0 A;  2PGZ A;  3TLT A;  3WTM A;  5J5F A;  2XYS A;  2BG9 B;  4HQP A;  3TLU A;  3C84 A;  4HFI A;  2BJ0 A;  5J5I A;  3ZDG A;  5AFM A;  2BG9 E;  3WTL A;  3SQ9 A;  3UU3 A;  4ZZC A;  5L4E A;  3TLV A;  2XQ6 A;  3UUB A;  5LXB A;  5HCJ A;  3UQ7 A;  3RIF A;  4A98 A;  4TNW A;  2W8F A;  4BFQ A;  3UU8 A;  4ILB A;  2BG9 A;  2BYS A;  2BYR A;  4QH1 A;  4DBM A;  4AFT A;  4IL4 A;  4LMK A;  4UM3 P;  2WNL A;  4ZK4 A;  4ZJT A;  2XQ7 A;  2YN6 A;  2XQ8 A;  3U8K A;  3SQ6 A;  5L4H A;  4LML A;  3WIP A;  4ALX A;  5TVC A;  5HEG A;  5J5H A;  4QAB A;  1UW6 A;  4ZK1 A;  5AFN A;  3LSV A;  5KE4 A;  2YME A;  2YOE A;  2XQA A;  2Y54 A;  2Y56 A;  2BR8 A;  4UM1 A;  3JAF A;  5AIN A;  2YKS A;  2XZ6 A;  3UU4 A;  5J5G A;  4XHE A;  2BYN A;  4HFD A;  2UZ6 A;  2XYT A;  4ZRU A;  4ZJS A;  3JAD A;  2XNT A;  4HFB A;  3GUA A;  4X5T A;  5AFH A;  3WTK A;  2PH9 A;  4ZR6 A;  4D01 A;  4F8H A;  3IGQ A;  1UX2 A;  2XNV A;  2XQ4 A;  5IUX A;  3ZDH A;  3EI0 A;  3P50 A;  3WTO A;  4Z91 A;  2XZ5 A;  3TLS A;  3T4M A;  4QAA A;  3TLW A;  3U8N A;  2YMD A;  4IL9 A;  4QAC A;  4TWH A;  2ZJU A;  4EZ1 A;  4UM3 A;  5SYO A;  5KZU A;  3UQ4 A;  3PMZ A;  3SIO A;  2XQ3 A;  4QH5 A;  4ZZB A;  4UY2 A;  4UM3 S;  2XQ9 A;  5CO5 A;  3U8J A;  3U8M A;  2WN9 A;  4QH4 A;  5HEH A;  5AFJ A;  2ZJV A;  2XQ5 A;  3EAM A;  4NZB A;  4AFG A;  5HCM A;  4TWF A;  5J0Z A;  4FRR A;  3U8L A;  3WTI A;  4Z90 A;  3WTJ A;  2WNJ A;  3RHW A;  4A97 A;  5L47 A;  4NPP A;  4PIR A;  3JAE A;  3C79 A;  4HFC A;  2BYP A;  2C9T A;  4TNV A;  2Y57 A;  2W8G A;  5AFK A;  3UU5 A;  5BW2 A;  3RQW A;  2BYQ A;  4WV9 A;  1UV6 A;  4ILC A;  4BQT A;  5JME A;  2WNC A;  4HFH A;  3UU6 A;  4B5D A;  3RQU A;  3PEO A;  5HEU A;  5AFL A;  2BR7 A;  4AFH A;  5FJV A;  2QC1 B; 
#chains in the Genus database with same CATH homology
 3SH1 A;  2BG9 C;  3EHZ A;  2Y7Y A;  4ILA A;  2Y58 A;  3P4W A;  5BRX A;  5HEO A;  2XNU A;  3ZKR A;  4LMJ A;  2WZY A;  4COF A;  4TWD A;  3WTH A;  5LG3 A;  3RIA A;  5BP0 A;  4HFE A;  2X00 D;  4XK9 A;  5HEJ A;  3RI5 A;  3WTN A;  5AFM B;  1I9B A;  4IRE A;  4UXU A;  2X00 A;  5CFB A;  2VL0 A;  2PGZ A;  3TLT A;  3WTM A;  5J5F A;  2XYS A;  2BG9 B;  4HQP A;  3TLU A;  3C84 A;  4HFI A;  2BJ0 A;  5J5I A;  3ZDG A;  5AFM A;  2BG9 E;  3WTL A;  3SQ9 A;  3UU3 A;  4ZZC A;  5L4E A;  3TLV A;  2XQ6 A;  3UUB A;  5LXB A;  5HCJ A;  3UQ7 A;  3RIF A;  4A98 A;  4TNW A;  2W8F A;  4BFQ A;  3UU8 A;  4ILB A;  2BG9 A;  2BYS A;  2BYR A;  4QH1 A;  4DBM A;  4AFT A;  4IL4 A;  4LMK A;  4UM3 P;  2WNL A;  4ZK4 A;  4ZJT A;  2XQ7 A;  2YN6 A;  2XQ8 A;  3U8K A;  3SQ6 A;  5L4H A;  4LML A;  3WIP A;  4ALX A;  5TVC A;  5HEG A;  5J5H A;  4QAB A;  1UW6 A;  4ZK1 A;  5AFN A;  3LSV A;  5KE4 A;  2YME A;  2YOE A;  2XQA A;  2Y54 A;  2Y56 A;  2BR8 A;  4UM1 A;  3JAF A;  5AIN A;  2YKS A;  2XZ6 A;  3UU4 A;  5J5G A;  4XHE A;  2BYN A;  4HFD A;  2UZ6 A;  2XYT A;  4ZRU A;  4ZJS A;  3JAD A;  2XNT A;  4HFB A;  3GUA A;  4X5T A;  5AFH A;  3WTK A;  2PH9 A;  4ZR6 A;  4D01 A;  4F8H A;  3IGQ A;  1UX2 A;  2XNV A;  2XQ4 A;  5IUX A;  3ZDH A;  3EI0 A;  3P50 A;  3WTO A;  4Z91 A;  2XZ5 A;  3TLS A;  3T4M A;  4QAA A;  3TLW A;  3U8N A;  2YMD A;  4IL9 A;  4QAC A;  4TWH A;  2ZJU A;  4EZ1 A;  4UM3 A;  5SYO A;  5KZU A;  3UQ4 A;  3PMZ A;  3SIO A;  2XQ3 A;  4QH5 A;  4ZZB A;  4UY2 A;  4UM3 S;  2XQ9 A;  5CO5 A;  3U8J A;  3U8M A;  2WN9 A;  4QH4 A;  5HEH A;  5AFJ A;  2ZJV A;  2XQ5 A;  3EAM A;  4NZB A;  4AFG A;  5HCM A;  4TWF A;  5J0Z A;  4FRR A;  3U8L A;  3WTI A;  4Z90 A;  3WTJ A;  2WNJ A;  3RHW A;  4A97 A;  5L47 A;  4NPP A;  4PIR A;  3JAE A;  3C79 A;  4HFC A;  2BYP A;  2C9T A;  4TNV A;  2Y57 A;  2W8G A;  5AFK A;  3UU5 A;  5BW2 A;  3RQW A;  2BYQ A;  4WV9 A;  1UV6 A;  4ILC A;  4BQT A;  5JME A;  2WNC A;  4HFH A;  3UU6 A;  4B5D A;  3RQU A;  3PEO A;  5HEU A;  5AFL A;  2BR7 A;  4AFH A;  5FJV A;  2QC1 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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