2BYQA

Crystal structure of aplysia californica achbp in complex with epibatidine
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
214
structure length
214
Chain Sequence
DDDDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Aplysia Achbp Complexes with Nicotinic Agonists and Antagonists Reveal Distinctive Binding Interfaces and Conformations.
pubmed doi rcsb
molecule keywords SOLUBLE ACETYLCHOLINE RECEPTOR
molecule tags Receptor
source organism Aplysia californica
total genus 51
structure length 214
sequence length 214
chains with identical sequence B, C, D, E
ec nomenclature
pdb deposition date 2005-08-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 2byqA00
2BR7A 4ZJSA 3UU3A 5CFBA 2BG9B 5J5GA 2BG9C 2XQAA 4UY2A 5J5HA 4QABA 5J5IA 4ZR6A 2PGZA 3U8LA 2BYPA 3GUAA 4ZZBA 3PMZA 4BQTA 3P4WA 3UQ7A 5IUXA 4Z91A 2BYRA 4ZK4A 3SIOA 2YN6A 5KZUA 3RIAA 4HFCA 4EZ1A 2XNUA 4ZK1A 4ILAA 4X5TA 2XYTA 5AFJA 4LMLA 3WTKA 4IL4A 2XQ3A 3P50A 4AFGA 2ZJUA 5CO5A 2X00D 5BP0A 3LSVA 3U8MA 5AFNA 5BRXA 5HCJA 2XQ5A 3ZKRA 5HEJA 4ZZCA 2WNCA 3RHWA 2BR8A 2W8FA 3EAMA 4ILCA 3T4MA 2XQ4A 5LG3A 4QAAA 4TWFA 2VL0A 4ALXA 3C79A 2XNVA 4HFBA 3JAFA 2WNJA 4XK9A 5HEUA 4F8HA 2WN9A 2XZ5A 4A97A 4IREA 3TLVA 5AFLA 2XZ6A 4A98A 2WZYA 2YOEA 2Y7YA 4UM1A 3WIPA 2XQ7A 3EHZA 3ZDGA 2X00A 2Y58A 3TLTA 1UW6A 4LMJA 5J0ZA 2BYNA 4HFEA 2YKSA 2C9TA 2XQ8A 3UU5A 3JADA 3WTOA 4FRRA 3U8JA 3SH1A 4AFTA 3WTMA 4XHEA 4UM3S 5JMEA 4UM3P 4Z90A 4QACA 3RIFA 2BG9A 2XNTA 4HQPA 4WV9A 5HCMA 2XYSA 2Y56A 3U8KA 3SQ9A 2BG9E 5AFHA 2WNLA 4TNWA 3TLSA 3UU4A 3WTLA 3RQUA 2UZ6A 5SYOA 4HFHA 3TLUA 3UU6A 2QC1B 3SQ6A 4TWHA 4UM3A 3C84A 5FJVA 5HEHA 4NZBA 3WTJA 2Y54A 3IGQA 3UU8A 3WTNA 5LXBA 4ZJTA 4DBMA 4HFDA 5HEOA 1UV6A 2BJ0A 4COFA 5J5FA 2ZJVA 5AINA 5KE4A 2W8GA 5L47A 4TNVA 4PIRA 3RQWA 5AFMA 3UQ4A 4HFIA 2YMDA 4UXUA 3UUBA 5BW2A 2BYQA 4ILBA 4D01A 4IL9A 3TLWA 4QH5A 2PH9A 5AFKA 2Y57A 4QH4A 4ZRUA 5HEGA 5L4HA 3U8NA 3WTHA 3WTIA 4BFQA 2YMEA 4TWDA 2BYSA 5TVCA 4AFHA 1I9BA 4LMKA 3JAEA 3RI5A 2XQ9A 3PEOA 2XQ6A 5L4EA 1UX2A 4NPPA 5AFMB 4B5DA 4QH1A 3EI0A 3ZDHA
chains in the Genus database with same CATH superfamily
2BR7A 4ZJSA 3UU3A 5CFBA 2BG9B 5J5GA 2BG9C 2XQAA 4UY2A 5J5HA 4QABA 5J5IA 4ZR6A 2PGZA 3U8LA 2BYPA 3GUAA 4ZZBA 3PMZA 4BQTA 3P4WA 3UQ7A 5IUXA 4Z91A 2BYRA 4ZK4A 3SIOA 2YN6A 5KZUA 3RIAA 4HFCA 4EZ1A 2XNUA 4ZK1A 4ILAA 4X5TA 2XYTA 5AFJA 4LMLA 3WTKA 4IL4A 2XQ3A 3P50A 4AFGA 2ZJUA 5CO5A 2X00D 5BP0A 3LSVA 3U8MA 5AFNA 5BRXA 5HCJA 2XQ5A 3ZKRA 5HEJA 4ZZCA 2WNCA 3RHWA 2BR8A 2W8FA 3EAMA 4ILCA 3T4MA 2XQ4A 5LG3A 4QAAA 4TWFA 2VL0A 4ALXA 3C79A 2XNVA 4HFBA 3JAFA 2WNJA 4XK9A 5HEUA 4F8HA 2WN9A 2XZ5A 4A97A 4IREA 3TLVA 5AFLA 2XZ6A 4A98A 2WZYA 2YOEA 2Y7YA 4UM1A 3WIPA 2XQ7A 3EHZA 3ZDGA 2X00A 2Y58A 3TLTA 1UW6A 4LMJA 5J0ZA 2BYNA 4HFEA 2YKSA 2C9TA 2XQ8A 3UU5A 3JADA 3WTOA 4FRRA 3U8JA 3SH1A 4AFTA 3WTMA 4XHEA 4UM3S 5JMEA 4UM3P 4Z90A 4QACA 3RIFA 2BG9A 2XNTA 4HQPA 4WV9A 5HCMA 2XYSA 2Y56A 3U8KA 3SQ9A 2BG9E 5AFHA 2WNLA 4TNWA 3TLSA 3UU4A 3WTLA 3RQUA 2UZ6A 5SYOA 4HFHA 3TLUA 3UU6A 2QC1B 3SQ6A 4TWHA 4UM3A 3C84A 5FJVA 5HEHA 4NZBA 3WTJA 2Y54A 3IGQA 3UU8A 3WTNA 5LXBA 4ZJTA 4DBMA 4HFDA 5HEOA 1UV6A 2BJ0A 4COFA 5J5FA 2ZJVA 5AINA 5KE4A 2W8GA 5L47A 4TNVA 4PIRA 3RQWA 5AFMA 3UQ4A 4HFIA 2YMDA 4UXUA 3UUBA 5BW2A 2BYQA 4ILBA 4D01A 4IL9A 3TLWA 4QH5A 2PH9A 5AFKA 2Y57A 4QH4A 4ZRUA 5HEGA 5L4HA 3U8NA 3WTHA 3WTIA 4BFQA 2YMEA 4TWDA 2BYSA 5TVCA 4AFHA 1I9BA 4LMKA 3JAEA 3RI5A 2XQ9A 3PEOA 2XQ6A 5L4EA 1UX2A 4NPPA 5AFMB 4B5DA 4QH1A 3EI0A 3ZDHA
chains in the Genus database with same CATH topology
2BR7A 4ZJSA 3UU3A 5CFBA 2BG9B 5J5GA 2BG9C 2XQAA 4UY2A 5J5HA 4QABA 5J5IA 4ZR6A 2PGZA 3U8LA 2BYPA 3GUAA 4ZZBA 3PMZA 4BQTA 3P4WA 3UQ7A 5IUXA 4Z91A 2BYRA 4ZK4A 3SIOA 2YN6A 5KZUA 3RIAA 4HFCA 4EZ1A 2XNUA 4ZK1A 4ILAA 4X5TA 2XYTA 5AFJA 4LMLA 3WTKA 4IL4A 2XQ3A 3P50A 4AFGA 2ZJUA 5CO5A 2X00D 5BP0A 3LSVA 3U8MA 5AFNA 5BRXA 5HCJA 2XQ5A 3ZKRA 5HEJA 4ZZCA 2WNCA 3RHWA 2BR8A 2W8FA 3EAMA 4ILCA 3T4MA 2XQ4A 5LG3A 4QAAA 4TWFA 2VL0A 4ALXA 3C79A 2XNVA 4HFBA 3JAFA 2WNJA 4XK9A 5HEUA 4F8HA 2WN9A 2XZ5A 4A97A 4IREA 3TLVA 5AFLA 2XZ6A 4A98A 2WZYA 2YOEA 2Y7YA 4UM1A 3WIPA 2XQ7A 3EHZA 3ZDGA 2X00A 2Y58A 3TLTA 1UW6A 4LMJA 5J0ZA 2BYNA 4HFEA 2YKSA 2C9TA 2XQ8A 3UU5A 3JADA 3WTOA 4FRRA 3U8JA 3SH1A 4AFTA 3WTMA 4XHEA 4UM3S 5JMEA 4UM3P 4Z90A 4QACA 3RIFA 2BG9A 2XNTA 4HQPA 4WV9A 5HCMA 2XYSA 2Y56A 3U8KA 3SQ9A 2BG9E 5AFHA 2WNLA 4TNWA 3TLSA 3UU4A 3WTLA 3RQUA 2UZ6A 5SYOA 4HFHA 3TLUA 3UU6A 2QC1B 3SQ6A 4TWHA 4UM3A 3C84A 5FJVA 5HEHA 4NZBA 3WTJA 2Y54A 3IGQA 3UU8A 3WTNA 5LXBA 4ZJTA 4DBMA 4HFDA 5HEOA 1UV6A 2BJ0A 4COFA 5J5FA 2ZJVA 5AINA 5KE4A 2W8GA 5L47A 4TNVA 4PIRA 3RQWA 5AFMA 3UQ4A 4HFIA 2YMDA 4UXUA 3UUBA 5BW2A 2BYQA 4ILBA 4D01A 4IL9A 3TLWA 4QH5A 2PH9A 5AFKA 2Y57A 4QH4A 4ZRUA 5HEGA 5L4HA 3U8NA 3WTHA 3WTIA 4BFQA 2YMEA 4TWDA 2BYSA 5TVCA 4AFHA 1I9BA 4LMKA 3JAEA 3RI5A 2XQ9A 3PEOA 2XQ6A 5L4EA 1UX2A 4NPPA 5AFMB 4B5DA 4QH1A 3EI0A 3ZDHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BR7 A;  4ZJS A;  3UU3 A;  5CFB A;  2BG9 B;  5J5G A;  2BG9 C;  2XQA A;  4UY2 A;  5J5H A;  4QAB A;  5J5I A;  4ZR6 A;  2PGZ A;  3U8L A;  2BYP A;  3GUA A;  4ZZB A;  3PMZ A;  4BQT A;  3P4W A;  3UQ7 A;  5IUX A;  4Z91 A;  2BYR A;  4ZK4 A;  3SIO A;  2YN6 A;  5KZU A;  3RIA A;  4HFC A;  4EZ1 A;  2XNU A;  4ZK1 A;  4ILA A;  4X5T A;  2XYT A;  5AFJ A;  4LML A;  3WTK A;  4IL4 A;  2XQ3 A;  3P50 A;  4AFG A;  2ZJU A;  5CO5 A;  2X00 D;  5BP0 A;  3LSV A;  3U8M A;  5AFN A;  5BRX A;  5HCJ A;  2XQ5 A;  3ZKR A;  5HEJ A;  4ZZC A;  2WNC A;  3RHW A;  2BR8 A;  2W8F A;  3EAM A;  4ILC A;  3T4M A;  2XQ4 A;  5LG3 A;  4QAA A;  4TWF A;  2VL0 A;  4ALX A;  3C79 A;  2XNV A;  4HFB A;  3JAF A;  2WNJ A;  4XK9 A;  5HEU A;  4F8H A;  2WN9 A;  2XZ5 A;  4A97 A;  4IRE A;  3TLV A;  5AFL A;  2XZ6 A;  4A98 A;  2WZY A;  2YOE A;  2Y7Y A;  4UM1 A;  3WIP A;  2XQ7 A;  3EHZ A;  3ZDG A;  2X00 A;  2Y58 A;  3TLT A;  1UW6 A;  4LMJ A;  5J0Z A;  2BYN A;  4HFE A;  2YKS A;  2C9T A;  2XQ8 A;  3UU5 A;  3JAD A;  3WTO A;  4FRR A;  3U8J A;  3SH1 A;  4AFT A;  3WTM A;  4XHE A;  4UM3 S;  5JME A;  4UM3 P;  4Z90 A;  4QAC A;  3RIF A;  2BG9 A;  2XNT A;  4HQP A;  4WV9 A;  5HCM A;  2XYS A;  2Y56 A;  3U8K A;  3SQ9 A;  2BG9 E;  5AFH A;  2WNL A;  4TNW A;  3TLS A;  3UU4 A;  3WTL A;  3RQU A;  2UZ6 A;  5SYO A;  4HFH A;  3TLU A;  3UU6 A;  2QC1 B;  3SQ6 A;  4TWH A;  4UM3 A;  3C84 A;  5FJV A;  5HEH A;  4NZB A;  3WTJ A;  2Y54 A;  3IGQ A;  3UU8 A;  3WTN A;  5LXB A;  4ZJT A;  4DBM A;  4HFD A;  5HEO A;  1UV6 A;  2BJ0 A;  4COF A;  5J5F A;  2ZJV A;  5AIN A;  5KE4 A;  2W8G A;  5L47 A;  4TNV A;  4PIR A;  3RQW A;  5AFM A;  3UQ4 A;  4HFI A;  2YMD A;  4UXU A;  3UUB A;  5BW2 A;  2BYQ A;  4ILB A;  4D01 A;  4IL9 A;  3TLW A;  4QH5 A;  2PH9 A;  5AFK A;  2Y57 A;  4QH4 A;  4ZRU A;  5HEG A;  5L4H A;  3U8N A;  3WTH A;  3WTI A;  4BFQ A;  2YME A;  4TWD A;  2BYS A;  5TVC A;  4AFH A;  1I9B A;  4LMK A;  3JAE A;  3RI5 A;  2XQ9 A;  3PEO A;  2XQ6 A;  5L4E A;  1UX2 A;  4NPP A;  5AFM B;  4B5D A;  4QH1 A;  3EI0 A;  3ZDH A; 
#chains in the Genus database with same CATH topology
 2BR7 A;  4ZJS A;  3UU3 A;  5CFB A;  2BG9 B;  5J5G A;  2BG9 C;  2XQA A;  4UY2 A;  5J5H A;  4QAB A;  5J5I A;  4ZR6 A;  2PGZ A;  3U8L A;  2BYP A;  3GUA A;  4ZZB A;  3PMZ A;  4BQT A;  3P4W A;  3UQ7 A;  5IUX A;  4Z91 A;  2BYR A;  4ZK4 A;  3SIO A;  2YN6 A;  5KZU A;  3RIA A;  4HFC A;  4EZ1 A;  2XNU A;  4ZK1 A;  4ILA A;  4X5T A;  2XYT A;  5AFJ A;  4LML A;  3WTK A;  4IL4 A;  2XQ3 A;  3P50 A;  4AFG A;  2ZJU A;  5CO5 A;  2X00 D;  5BP0 A;  3LSV A;  3U8M A;  5AFN A;  5BRX A;  5HCJ A;  2XQ5 A;  3ZKR A;  5HEJ A;  4ZZC A;  2WNC A;  3RHW A;  2BR8 A;  2W8F A;  3EAM A;  4ILC A;  3T4M A;  2XQ4 A;  5LG3 A;  4QAA A;  4TWF A;  2VL0 A;  4ALX A;  3C79 A;  2XNV A;  4HFB A;  3JAF A;  2WNJ A;  4XK9 A;  5HEU A;  4F8H A;  2WN9 A;  2XZ5 A;  4A97 A;  4IRE A;  3TLV A;  5AFL A;  2XZ6 A;  4A98 A;  2WZY A;  2YOE A;  2Y7Y A;  4UM1 A;  3WIP A;  2XQ7 A;  3EHZ A;  3ZDG A;  2X00 A;  2Y58 A;  3TLT A;  1UW6 A;  4LMJ A;  5J0Z A;  2BYN A;  4HFE A;  2YKS A;  2C9T A;  2XQ8 A;  3UU5 A;  3JAD A;  3WTO A;  4FRR A;  3U8J A;  3SH1 A;  4AFT A;  3WTM A;  4XHE A;  4UM3 S;  5JME A;  4UM3 P;  4Z90 A;  4QAC A;  3RIF A;  2BG9 A;  2XNT A;  4HQP A;  4WV9 A;  5HCM A;  2XYS A;  2Y56 A;  3U8K A;  3SQ9 A;  2BG9 E;  5AFH A;  2WNL A;  4TNW A;  3TLS A;  3UU4 A;  3WTL A;  3RQU A;  2UZ6 A;  5SYO A;  4HFH A;  3TLU A;  3UU6 A;  2QC1 B;  3SQ6 A;  4TWH A;  4UM3 A;  3C84 A;  5FJV A;  5HEH A;  4NZB A;  3WTJ A;  2Y54 A;  3IGQ A;  3UU8 A;  3WTN A;  5LXB A;  4ZJT A;  4DBM A;  4HFD A;  5HEO A;  1UV6 A;  2BJ0 A;  4COF A;  5J5F A;  2ZJV A;  5AIN A;  5KE4 A;  2W8G A;  5L47 A;  4TNV A;  4PIR A;  3RQW A;  5AFM A;  3UQ4 A;  4HFI A;  2YMD A;  4UXU A;  3UUB A;  5BW2 A;  2BYQ A;  4ILB A;  4D01 A;  4IL9 A;  3TLW A;  4QH5 A;  2PH9 A;  5AFK A;  2Y57 A;  4QH4 A;  4ZRU A;  5HEG A;  5L4H A;  3U8N A;  3WTH A;  3WTI A;  4BFQ A;  2YME A;  4TWD A;  2BYS A;  5TVC A;  4AFH A;  1I9B A;  4LMK A;  3JAE A;  3RI5 A;  2XQ9 A;  3PEO A;  2XQ6 A;  5L4E A;  1UX2 A;  4NPP A;  5AFM B;  4B5D A;  4QH1 A;  3EI0 A;  3ZDH A; 
#chains in the Genus database with same CATH homology
 2BR7 A;  4ZJS A;  3UU3 A;  5CFB A;  2BG9 B;  5J5G A;  2BG9 C;  2XQA A;  4UY2 A;  5J5H A;  4QAB A;  5J5I A;  4ZR6 A;  2PGZ A;  3U8L A;  2BYP A;  3GUA A;  4ZZB A;  3PMZ A;  4BQT A;  3P4W A;  3UQ7 A;  5IUX A;  4Z91 A;  2BYR A;  4ZK4 A;  3SIO A;  2YN6 A;  5KZU A;  3RIA A;  4HFC A;  4EZ1 A;  2XNU A;  4ZK1 A;  4ILA A;  4X5T A;  2XYT A;  5AFJ A;  4LML A;  3WTK A;  4IL4 A;  2XQ3 A;  3P50 A;  4AFG A;  2ZJU A;  5CO5 A;  2X00 D;  5BP0 A;  3LSV A;  3U8M A;  5AFN A;  5BRX A;  5HCJ A;  2XQ5 A;  3ZKR A;  5HEJ A;  4ZZC A;  2WNC A;  3RHW A;  2BR8 A;  2W8F A;  3EAM A;  4ILC A;  3T4M A;  2XQ4 A;  5LG3 A;  4QAA A;  4TWF A;  2VL0 A;  4ALX A;  3C79 A;  2XNV A;  4HFB A;  3JAF A;  2WNJ A;  4XK9 A;  5HEU A;  4F8H A;  2WN9 A;  2XZ5 A;  4A97 A;  4IRE A;  3TLV A;  5AFL A;  2XZ6 A;  4A98 A;  2WZY A;  2YOE A;  2Y7Y A;  4UM1 A;  3WIP A;  2XQ7 A;  3EHZ A;  3ZDG A;  2X00 A;  2Y58 A;  3TLT A;  1UW6 A;  4LMJ A;  5J0Z A;  2BYN A;  4HFE A;  2YKS A;  2C9T A;  2XQ8 A;  3UU5 A;  3JAD A;  3WTO A;  4FRR A;  3U8J A;  3SH1 A;  4AFT A;  3WTM A;  4XHE A;  4UM3 S;  5JME A;  4UM3 P;  4Z90 A;  4QAC A;  3RIF A;  2BG9 A;  2XNT A;  4HQP A;  4WV9 A;  5HCM A;  2XYS A;  2Y56 A;  3U8K A;  3SQ9 A;  2BG9 E;  5AFH A;  2WNL A;  4TNW A;  3TLS A;  3UU4 A;  3WTL A;  3RQU A;  2UZ6 A;  5SYO A;  4HFH A;  3TLU A;  3UU6 A;  2QC1 B;  3SQ6 A;  4TWH A;  4UM3 A;  3C84 A;  5FJV A;  5HEH A;  4NZB A;  3WTJ A;  2Y54 A;  3IGQ A;  3UU8 A;  3WTN A;  5LXB A;  4ZJT A;  4DBM A;  4HFD A;  5HEO A;  1UV6 A;  2BJ0 A;  4COF A;  5J5F A;  2ZJV A;  5AIN A;  5KE4 A;  2W8G A;  5L47 A;  4TNV A;  4PIR A;  3RQW A;  5AFM A;  3UQ4 A;  4HFI A;  2YMD A;  4UXU A;  3UUB A;  5BW2 A;  2BYQ A;  4ILB A;  4D01 A;  4IL9 A;  3TLW A;  4QH5 A;  2PH9 A;  5AFK A;  2Y57 A;  4QH4 A;  4ZRU A;  5HEG A;  5L4H A;  3U8N A;  3WTH A;  3WTI A;  4BFQ A;  2YME A;  4TWD A;  2BYS A;  5TVC A;  4AFH A;  1I9B A;  4LMK A;  3JAE A;  3RI5 A;  2XQ9 A;  3PEO A;  2XQ6 A;  5L4E A;  1UX2 A;  4NPP A;  5AFM B;  4B5D A;  4QH1 A;  3EI0 A;  3ZDH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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