2XYTA

Crystal structure of aplysia californica achbp in complex with d- tubocurarine
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
205
structure length
205
Chain Sequence
QANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKVDSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGVTCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Structural and Mutagenic Blueprint for Molecular Recognition of Strychnine and D-Tubocurarine by Different Cys-Loop Receptors.
pubmed doi rcsb
molecule tags Receptor
source organism Aplysia californica
molecule keywords SOLUBLE ACETYLCHOLINE RECEPTOR
total genus 51
structure length 205
sequence length 205
chains with identical sequence B, C, D, E, F, G, H, I, J
ec nomenclature
pdb deposition date 2010-11-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 2xytA00
2X00D 5L4EA 5L47A 4BFQA 4HFDA 5J0ZA 2WNJA 4QABA 4QACA 5HEJA 3RQWA 3U8NA 4COFA 2X00A 3IGQA 4ZK1A 4UM1A 4ZRUA 2XNTA 3EAMA 4D01A 5LG3A 3C84A 3SQ9A 5HEGA 3RIAA 2BG9E 4ZZBA 5AFMB 3WTLA 5CFBA 2XQ7A 5BRXA 3SQ6A 4TNVA 3UU6A 3WTNA 3WTOA 2XYTA 2Y54A 2Y58A 3JADA 2PGZA 2YN6A 4TWDA 4QH5A 5AFJA 4TNWA 2XQ9A 3WTIA 4UM3A 5HCJA 4ALXA 3UU8A 2W8FA 2BJ0A 4ILBA 5BW2A 2XZ6A 2BG9B 3SIOA 3RQUA 2YMEA 4A98A 2VL0A 3TLSA 5AFNA 2BYQA 5BP0A 5KZUA 3U8KA 3UQ7A 4AFTA 1UW6A 4HFHA 4LMJA 4AFHA 5SYOA 2PH9A 5HEUA 3UU4A 4HFCA 4XK9A 4ILCA 3U8MA 4ILAA 2BYSA 4BQTA 3TLVA 5HEOA 4QH4A 4HFBA 2Y7YA 2XYSA 2UZ6A 4WV9A 4FRRA 2WNCA 4DBMA 4EZ1A 4ZZCA 2XQ4A 2W8GA 3TLUA 5J5HA 4X5TA 4IL4A 3JAFA 5TVCA 2BYNA 4LMLA 5LXBA 3UU5A 3U8JA 4HFIA 4PIRA 5AFLA 4Z91A 2XNVA 2XQ8A 2BG9C 2XNUA 3ZDHA 4ZR6A 4Z90A 5FJVA 4NPPA 4UY2A 4UM3S 4AFGA 2XQ3A 4HFEA 1UV6A 2ZJUA 3JAEA 3PEOA 3RHWA 3WTKA 3TLWA 5AFKA 5J5FA 3RI5A 4LMKA 2XQ5A 2XZ5A 3RIFA 3UUBA 5IUXA 4F8HA 3P4WA 2BR7A 2BYPA 4IREA 3TLTA 4A97A 4B5DA 2WNLA 2Y57A 5JMEA 4TWFA 2WZYA 4UXUA 3UU3A 1UX2A 3U8LA 3ZDGA 2C9TA 3WIPA 4IL9A 5AFMA 2YOEA 4NZBA 3ZKRA 5J5GA 5HCMA 2YMDA 3GUAA 3PMZA 3WTMA 1I9BA 3UQ4A 3C79A 4ZK4A 3WTHA 3P50A 2QC1B 5CO5A 2BYRA 3EHZA 2Y56A 3EI0A 4XHEA 5L4HA 4QH1A 5AINA 2WN9A 4ZJSA 4QAAA 3T4MA 2BR8A 3WTJA 5AFHA 2XQ6A 5HEHA 5J5IA 2YKSA 4TWHA 3SH1A 2BG9A 5KE4A 4ZJTA 2ZJVA 3LSVA 4HQPA 2XQAA 4UM3P
chains in the Genus database with same CATH superfamily
2X00D 5L4EA 5L47A 4BFQA 4HFDA 5J0ZA 2WNJA 4QABA 4QACA 5HEJA 3RQWA 3U8NA 4COFA 2X00A 3IGQA 4ZK1A 4UM1A 4ZRUA 2XNTA 3EAMA 4D01A 5LG3A 3C84A 3SQ9A 5HEGA 3RIAA 2BG9E 4ZZBA 5AFMB 3WTLA 5CFBA 2XQ7A 5BRXA 3SQ6A 4TNVA 3UU6A 3WTNA 3WTOA 2XYTA 2Y54A 2Y58A 3JADA 2PGZA 2YN6A 4TWDA 4QH5A 5AFJA 4TNWA 2XQ9A 3WTIA 4UM3A 5HCJA 4ALXA 3UU8A 2W8FA 2BJ0A 4ILBA 5BW2A 2XZ6A 2BG9B 3SIOA 3RQUA 2YMEA 4A98A 2VL0A 3TLSA 5AFNA 2BYQA 5BP0A 5KZUA 3U8KA 3UQ7A 4AFTA 1UW6A 4HFHA 4LMJA 4AFHA 5SYOA 2PH9A 5HEUA 3UU4A 4HFCA 4XK9A 4ILCA 3U8MA 4ILAA 2BYSA 4BQTA 3TLVA 5HEOA 4QH4A 4HFBA 2Y7YA 2XYSA 2UZ6A 4WV9A 4FRRA 2WNCA 4DBMA 4EZ1A 4ZZCA 2XQ4A 2W8GA 3TLUA 5J5HA 4X5TA 4IL4A 3JAFA 5TVCA 2BYNA 4LMLA 5LXBA 3UU5A 3U8JA 4HFIA 4PIRA 5AFLA 4Z91A 2XNVA 2XQ8A 2BG9C 2XNUA 3ZDHA 4ZR6A 4Z90A 5FJVA 4NPPA 4UY2A 4UM3S 4AFGA 2XQ3A 4HFEA 1UV6A 2ZJUA 3JAEA 3PEOA 3RHWA 3WTKA 3TLWA 5AFKA 5J5FA 3RI5A 4LMKA 2XQ5A 2XZ5A 3RIFA 3UUBA 5IUXA 4F8HA 3P4WA 2BR7A 2BYPA 4IREA 3TLTA 4A97A 4B5DA 2WNLA 2Y57A 5JMEA 4TWFA 2WZYA 4UXUA 3UU3A 1UX2A 3U8LA 3ZDGA 2C9TA 3WIPA 4IL9A 5AFMA 2YOEA 4NZBA 3ZKRA 5J5GA 5HCMA 2YMDA 3GUAA 3PMZA 3WTMA 1I9BA 3UQ4A 3C79A 4ZK4A 3WTHA 3P50A 2QC1B 5CO5A 2BYRA 3EHZA 2Y56A 3EI0A 4XHEA 5L4HA 4QH1A 5AINA 2WN9A 4ZJSA 4QAAA 3T4MA 2BR8A 3WTJA 5AFHA 2XQ6A 5HEHA 5J5IA 2YKSA 4TWHA 3SH1A 2BG9A 5KE4A 4ZJTA 2ZJVA 3LSVA 4HQPA 2XQAA 4UM3P
chains in the Genus database with same CATH topology
2X00D 5L4EA 5L47A 4BFQA 4HFDA 5J0ZA 2WNJA 4QABA 4QACA 5HEJA 3RQWA 3U8NA 4COFA 2X00A 3IGQA 4ZK1A 4UM1A 4ZRUA 2XNTA 3EAMA 4D01A 5LG3A 3C84A 3SQ9A 5HEGA 3RIAA 2BG9E 4ZZBA 5AFMB 3WTLA 5CFBA 2XQ7A 5BRXA 3SQ6A 4TNVA 3UU6A 3WTNA 3WTOA 2XYTA 2Y54A 2Y58A 3JADA 2PGZA 2YN6A 4TWDA 4QH5A 5AFJA 4TNWA 2XQ9A 3WTIA 4UM3A 5HCJA 4ALXA 3UU8A 2W8FA 2BJ0A 4ILBA 5BW2A 2XZ6A 2BG9B 3SIOA 3RQUA 2YMEA 4A98A 2VL0A 3TLSA 5AFNA 2BYQA 5BP0A 5KZUA 3U8KA 3UQ7A 4AFTA 1UW6A 4HFHA 4LMJA 4AFHA 5SYOA 2PH9A 5HEUA 3UU4A 4HFCA 4XK9A 4ILCA 3U8MA 4ILAA 2BYSA 4BQTA 3TLVA 5HEOA 4QH4A 4HFBA 2Y7YA 2XYSA 2UZ6A 4WV9A 4FRRA 2WNCA 4DBMA 4EZ1A 4ZZCA 2XQ4A 2W8GA 3TLUA 5J5HA 4X5TA 4IL4A 3JAFA 5TVCA 2BYNA 4LMLA 5LXBA 3UU5A 3U8JA 4HFIA 4PIRA 5AFLA 4Z91A 2XNVA 2XQ8A 2BG9C 2XNUA 3ZDHA 4ZR6A 4Z90A 5FJVA 4NPPA 4UY2A 4UM3S 4AFGA 2XQ3A 4HFEA 1UV6A 2ZJUA 3JAEA 3PEOA 3RHWA 3WTKA 3TLWA 5AFKA 5J5FA 3RI5A 4LMKA 2XQ5A 2XZ5A 3RIFA 3UUBA 5IUXA 4F8HA 3P4WA 2BR7A 2BYPA 4IREA 3TLTA 4A97A 4B5DA 2WNLA 2Y57A 5JMEA 4TWFA 2WZYA 4UXUA 3UU3A 1UX2A 3U8LA 3ZDGA 2C9TA 3WIPA 4IL9A 5AFMA 2YOEA 4NZBA 3ZKRA 5J5GA 5HCMA 2YMDA 3GUAA 3PMZA 3WTMA 1I9BA 3UQ4A 3C79A 4ZK4A 3WTHA 3P50A 2QC1B 5CO5A 2BYRA 3EHZA 2Y56A 3EI0A 4XHEA 5L4HA 4QH1A 5AINA 2WN9A 4ZJSA 4QAAA 3T4MA 2BR8A 3WTJA 5AFHA 2XQ6A 5HEHA 5J5IA 2YKSA 4TWHA 3SH1A 2BG9A 5KE4A 4ZJTA 2ZJVA 3LSVA 4HQPA 2XQAA 4UM3P
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2X00 D;  5L4E A;  5L47 A;  4BFQ A;  4HFD A;  5J0Z A;  2WNJ A;  4QAB A;  4QAC A;  5HEJ A;  3RQW A;  3U8N A;  4COF A;  2X00 A;  3IGQ A;  4ZK1 A;  4UM1 A;  4ZRU A;  2XNT A;  3EAM A;  4D01 A;  5LG3 A;  3C84 A;  3SQ9 A;  5HEG A;  3RIA A;  2BG9 E;  4ZZB A;  5AFM B;  3WTL A;  5CFB A;  2XQ7 A;  5BRX A;  3SQ6 A;  4TNV A;  3UU6 A;  3WTN A;  3WTO A;  2XYT A;  2Y54 A;  2Y58 A;  3JAD A;  2PGZ A;  2YN6 A;  4TWD A;  4QH5 A;  5AFJ A;  4TNW A;  2XQ9 A;  3WTI A;  4UM3 A;  5HCJ A;  4ALX A;  3UU8 A;  2W8F A;  2BJ0 A;  4ILB A;  5BW2 A;  2XZ6 A;  2BG9 B;  3SIO A;  3RQU A;  2YME A;  4A98 A;  2VL0 A;  3TLS A;  5AFN A;  2BYQ A;  5BP0 A;  5KZU A;  3U8K A;  3UQ7 A;  4AFT A;  1UW6 A;  4HFH A;  4LMJ A;  4AFH A;  5SYO A;  2PH9 A;  5HEU A;  3UU4 A;  4HFC A;  4XK9 A;  4ILC A;  3U8M A;  4ILA A;  2BYS A;  4BQT A;  3TLV A;  5HEO A;  4QH4 A;  4HFB A;  2Y7Y A;  2XYS A;  2UZ6 A;  4WV9 A;  4FRR A;  2WNC A;  4DBM A;  4EZ1 A;  4ZZC A;  2XQ4 A;  2W8G A;  3TLU A;  5J5H A;  4X5T A;  4IL4 A;  3JAF A;  5TVC A;  2BYN A;  4LML A;  5LXB A;  3UU5 A;  3U8J A;  4HFI A;  4PIR A;  5AFL A;  4Z91 A;  2XNV A;  2XQ8 A;  2BG9 C;  2XNU A;  3ZDH A;  4ZR6 A;  4Z90 A;  5FJV A;  4NPP A;  4UY2 A;  4UM3 S;  4AFG A;  2XQ3 A;  4HFE A;  1UV6 A;  2ZJU A;  3JAE A;  3PEO A;  3RHW A;  3WTK A;  3TLW A;  5AFK A;  5J5F A;  3RI5 A;  4LMK A;  2XQ5 A;  2XZ5 A;  3RIF A;  3UUB A;  5IUX A;  4F8H A;  3P4W A;  2BR7 A;  2BYP A;  4IRE A;  3TLT A;  4A97 A;  4B5D A;  2WNL A;  2Y57 A;  5JME A;  4TWF A;  2WZY A;  4UXU A;  3UU3 A;  1UX2 A;  3U8L A;  3ZDG A;  2C9T A;  3WIP A;  4IL9 A;  5AFM A;  2YOE A;  4NZB A;  3ZKR A;  5J5G A;  5HCM A;  2YMD A;  3GUA A;  3PMZ A;  3WTM A;  1I9B A;  3UQ4 A;  3C79 A;  4ZK4 A;  3WTH A;  3P50 A;  2QC1 B;  5CO5 A;  2BYR A;  3EHZ A;  2Y56 A;  3EI0 A;  4XHE A;  5L4H A;  4QH1 A;  5AIN A;  2WN9 A;  4ZJS A;  4QAA A;  3T4M A;  2BR8 A;  3WTJ A;  5AFH A;  2XQ6 A;  5HEH A;  5J5I A;  2YKS A;  4TWH A;  3SH1 A;  2BG9 A;  5KE4 A;  4ZJT A;  2ZJV A;  3LSV A;  4HQP A;  2XQA A;  4UM3 P; 
#chains in the Genus database with same CATH topology
 2X00 D;  5L4E A;  5L47 A;  4BFQ A;  4HFD A;  5J0Z A;  2WNJ A;  4QAB A;  4QAC A;  5HEJ A;  3RQW A;  3U8N A;  4COF A;  2X00 A;  3IGQ A;  4ZK1 A;  4UM1 A;  4ZRU A;  2XNT A;  3EAM A;  4D01 A;  5LG3 A;  3C84 A;  3SQ9 A;  5HEG A;  3RIA A;  2BG9 E;  4ZZB A;  5AFM B;  3WTL A;  5CFB A;  2XQ7 A;  5BRX A;  3SQ6 A;  4TNV A;  3UU6 A;  3WTN A;  3WTO A;  2XYT A;  2Y54 A;  2Y58 A;  3JAD A;  2PGZ A;  2YN6 A;  4TWD A;  4QH5 A;  5AFJ A;  4TNW A;  2XQ9 A;  3WTI A;  4UM3 A;  5HCJ A;  4ALX A;  3UU8 A;  2W8F A;  2BJ0 A;  4ILB A;  5BW2 A;  2XZ6 A;  2BG9 B;  3SIO A;  3RQU A;  2YME A;  4A98 A;  2VL0 A;  3TLS A;  5AFN A;  2BYQ A;  5BP0 A;  5KZU A;  3U8K A;  3UQ7 A;  4AFT A;  1UW6 A;  4HFH A;  4LMJ A;  4AFH A;  5SYO A;  2PH9 A;  5HEU A;  3UU4 A;  4HFC A;  4XK9 A;  4ILC A;  3U8M A;  4ILA A;  2BYS A;  4BQT A;  3TLV A;  5HEO A;  4QH4 A;  4HFB A;  2Y7Y A;  2XYS A;  2UZ6 A;  4WV9 A;  4FRR A;  2WNC A;  4DBM A;  4EZ1 A;  4ZZC A;  2XQ4 A;  2W8G A;  3TLU A;  5J5H A;  4X5T A;  4IL4 A;  3JAF A;  5TVC A;  2BYN A;  4LML A;  5LXB A;  3UU5 A;  3U8J A;  4HFI A;  4PIR A;  5AFL A;  4Z91 A;  2XNV A;  2XQ8 A;  2BG9 C;  2XNU A;  3ZDH A;  4ZR6 A;  4Z90 A;  5FJV A;  4NPP A;  4UY2 A;  4UM3 S;  4AFG A;  2XQ3 A;  4HFE A;  1UV6 A;  2ZJU A;  3JAE A;  3PEO A;  3RHW A;  3WTK A;  3TLW A;  5AFK A;  5J5F A;  3RI5 A;  4LMK A;  2XQ5 A;  2XZ5 A;  3RIF A;  3UUB A;  5IUX A;  4F8H A;  3P4W A;  2BR7 A;  2BYP A;  4IRE A;  3TLT A;  4A97 A;  4B5D A;  2WNL A;  2Y57 A;  5JME A;  4TWF A;  2WZY A;  4UXU A;  3UU3 A;  1UX2 A;  3U8L A;  3ZDG A;  2C9T A;  3WIP A;  4IL9 A;  5AFM A;  2YOE A;  4NZB A;  3ZKR A;  5J5G A;  5HCM A;  2YMD A;  3GUA A;  3PMZ A;  3WTM A;  1I9B A;  3UQ4 A;  3C79 A;  4ZK4 A;  3WTH A;  3P50 A;  2QC1 B;  5CO5 A;  2BYR A;  3EHZ A;  2Y56 A;  3EI0 A;  4XHE A;  5L4H A;  4QH1 A;  5AIN A;  2WN9 A;  4ZJS A;  4QAA A;  3T4M A;  2BR8 A;  3WTJ A;  5AFH A;  2XQ6 A;  5HEH A;  5J5I A;  2YKS A;  4TWH A;  3SH1 A;  2BG9 A;  5KE4 A;  4ZJT A;  2ZJV A;  3LSV A;  4HQP A;  2XQA A;  4UM3 P; 
#chains in the Genus database with same CATH homology
 2X00 D;  5L4E A;  5L47 A;  4BFQ A;  4HFD A;  5J0Z A;  2WNJ A;  4QAB A;  4QAC A;  5HEJ A;  3RQW A;  3U8N A;  4COF A;  2X00 A;  3IGQ A;  4ZK1 A;  4UM1 A;  4ZRU A;  2XNT A;  3EAM A;  4D01 A;  5LG3 A;  3C84 A;  3SQ9 A;  5HEG A;  3RIA A;  2BG9 E;  4ZZB A;  5AFM B;  3WTL A;  5CFB A;  2XQ7 A;  5BRX A;  3SQ6 A;  4TNV A;  3UU6 A;  3WTN A;  3WTO A;  2XYT A;  2Y54 A;  2Y58 A;  3JAD A;  2PGZ A;  2YN6 A;  4TWD A;  4QH5 A;  5AFJ A;  4TNW A;  2XQ9 A;  3WTI A;  4UM3 A;  5HCJ A;  4ALX A;  3UU8 A;  2W8F A;  2BJ0 A;  4ILB A;  5BW2 A;  2XZ6 A;  2BG9 B;  3SIO A;  3RQU A;  2YME A;  4A98 A;  2VL0 A;  3TLS A;  5AFN A;  2BYQ A;  5BP0 A;  5KZU A;  3U8K A;  3UQ7 A;  4AFT A;  1UW6 A;  4HFH A;  4LMJ A;  4AFH A;  5SYO A;  2PH9 A;  5HEU A;  3UU4 A;  4HFC A;  4XK9 A;  4ILC A;  3U8M A;  4ILA A;  2BYS A;  4BQT A;  3TLV A;  5HEO A;  4QH4 A;  4HFB A;  2Y7Y A;  2XYS A;  2UZ6 A;  4WV9 A;  4FRR A;  2WNC A;  4DBM A;  4EZ1 A;  4ZZC A;  2XQ4 A;  2W8G A;  3TLU A;  5J5H A;  4X5T A;  4IL4 A;  3JAF A;  5TVC A;  2BYN A;  4LML A;  5LXB A;  3UU5 A;  3U8J A;  4HFI A;  4PIR A;  5AFL A;  4Z91 A;  2XNV A;  2XQ8 A;  2BG9 C;  2XNU A;  3ZDH A;  4ZR6 A;  4Z90 A;  5FJV A;  4NPP A;  4UY2 A;  4UM3 S;  4AFG A;  2XQ3 A;  4HFE A;  1UV6 A;  2ZJU A;  3JAE A;  3PEO A;  3RHW A;  3WTK A;  3TLW A;  5AFK A;  5J5F A;  3RI5 A;  4LMK A;  2XQ5 A;  2XZ5 A;  3RIF A;  3UUB A;  5IUX A;  4F8H A;  3P4W A;  2BR7 A;  2BYP A;  4IRE A;  3TLT A;  4A97 A;  4B5D A;  2WNL A;  2Y57 A;  5JME A;  4TWF A;  2WZY A;  4UXU A;  3UU3 A;  1UX2 A;  3U8L A;  3ZDG A;  2C9T A;  3WIP A;  4IL9 A;  5AFM A;  2YOE A;  4NZB A;  3ZKR A;  5J5G A;  5HCM A;  2YMD A;  3GUA A;  3PMZ A;  3WTM A;  1I9B A;  3UQ4 A;  3C79 A;  4ZK4 A;  3WTH A;  3P50 A;  2QC1 B;  5CO5 A;  2BYR A;  3EHZ A;  2Y56 A;  3EI0 A;  4XHE A;  5L4H A;  4QH1 A;  5AIN A;  2WN9 A;  4ZJS A;  4QAA A;  3T4M A;  2BR8 A;  3WTJ A;  5AFH A;  2XQ6 A;  5HEH A;  5J5I A;  2YKS A;  4TWH A;  3SH1 A;  2BG9 A;  5KE4 A;  4ZJT A;  2ZJV A;  3LSV A;  4HQP A;  2XQA A;  4UM3 P; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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