3ZDHA

Crystal structure of ls-achbp complexed with carbamoylcholine analogue n,n-dimethyl-4-(1-methyl-1h-imidazol-2-yloxy)butan-2-amine
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
204
structure length
200
Chain Sequence
LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Synthesis, Pharmacology, and Biostructural Characterization of Novel Alpha(4)Beta(2) Nicotinic Acetylcholine Receptor Agonists.
pubmed doi rcsb
molecule tags Acetylcholine-binding protein
source organism Lymnaea stagnalis
molecule keywords ACETYLCHOLINE BINDING PROTEIN
total genus 49
structure length 200
sequence length 204
chains with identical sequence B, C, D, E, F, G, H, I, J
ec nomenclature
pdb deposition date 2012-11-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 3zdhA00
5BP0A 3WIPA 3U8LA 3WTOA 2BG9C 4ZJSA 3TLWA 4ZK1A 1UW6A 2Y56A 4QH4A 2XQ6A 4NPPA 5J5IA 4ILBA 4COFA 2XNUA 2WN9A 2XQ3A 3UU4A 3WTHA 5J5HA 4QH5A 3TLVA 5LG3A 4TWDA 4XHEA 4ZR6A 4QH1A 5AFMB 2W8FA 4UY2A 4TWHA 4EZ1A 3PEOA 5LXBA 2XQ5A 4AFGA 2YN6A 4DBMA 4TNVA 4QACA 3SH1A 4LMJA 3RQWA 3UU3A 3WTLA 2XQ8A 2BG9B 3RIAA 4UM3P 3RHWA 3T4MA 2X00D 5FJVA 4LMKA 3UU8A 2Y57A 2Y58A 3EHZA 4HFCA 5KZUA 5AFKA 5J5FA 2ZJUA 4QABA 3TLSA 4HFDA 2XYTA 4TNWA 2XZ5A 3SQ9A 3UU6A 4D01A 5TVCA 2WNJA 4IREA 2WZYA 4Z91A 4HFBA 2XYSA 2ZJVA 2YKSA 4ILAA 4ILCA 5JMEA 3RI5A 3U8KA 3JAFA 2XQ7A 4A97A 3C84A 4HFIA 3ZDHA 2BJ0A 4ALXA 2Y7YA 4ZZCA 2BYRA 2W8GA 4BQTA 2WNLA 5AINA 5KE4A 3WTIA 5IUXA 3U8MA 4F8HA 2YMEA 5CO5A 3U8JA 4ZJTA 4Z90A 1I9BA 3WTNA 4AFHA 4HFEA 3P50A 5AFJA 5L47A 2XNTA 3RQUA 2XQAA 4IL9A 2BYSA 2C9TA 4UM1A 3PMZA 4UXUA 4BFQA 4ZK4A 3WTJA 2BYQA 3WTKA 3UQ7A 3U8NA 5J0ZA 2X00A 2BR7A 4NZBA 4B5DA 2XNVA 5J5GA 3TLUA 4A98A 5AFMA 4ZZBA 3ZKRA 5HEUA 3JADA 2PGZA 5AFLA 4FRRA 4TWFA 4WV9A 4UM3S 3SQ6A 2YOEA 2WNCA 2Y54A 4XK9A 2BG9A 5AFNA 5L4EA 3WTMA 3IGQA 2PH9A 5HEJA 4AFTA 4LMLA 5HEGA 2BR8A 3C79A 3EAMA 5CFBA 5BW2A 3LSVA 5HCJA 2BG9E 3EI0A 4IL4A 2UZ6A 3UU5A 5HEHA 4QAAA 5AFHA 1UV6A 4ZRUA 3JAEA 5BRXA 5HEOA 2QC1B 5SYOA 3UUBA 3TLTA 3GUAA 4HQPA 4HFHA 5HCMA 4PIRA 2XQ4A 2VL0A 2XZ6A 4X5TA 4UM3A 3UQ4A 5L4HA 2BYNA 3SIOA 2XQ9A 2BYPA 2YMDA 1UX2A 3ZDGA 3RIFA 3P4WA
chains in the Genus database with same CATH superfamily
5BP0A 3WIPA 3U8LA 3WTOA 2BG9C 4ZJSA 3TLWA 4ZK1A 1UW6A 2Y56A 4QH4A 2XQ6A 4NPPA 5J5IA 4ILBA 4COFA 2XNUA 2WN9A 2XQ3A 3UU4A 3WTHA 5J5HA 4QH5A 3TLVA 5LG3A 4TWDA 4XHEA 4ZR6A 4QH1A 5AFMB 2W8FA 4UY2A 4TWHA 4EZ1A 3PEOA 5LXBA 2XQ5A 4AFGA 2YN6A 4DBMA 4TNVA 4QACA 3SH1A 4LMJA 3RQWA 3UU3A 3WTLA 2XQ8A 2BG9B 3RIAA 4UM3P 3RHWA 3T4MA 2X00D 5FJVA 4LMKA 3UU8A 2Y57A 2Y58A 3EHZA 4HFCA 5KZUA 5AFKA 5J5FA 2ZJUA 4QABA 3TLSA 4HFDA 2XYTA 4TNWA 2XZ5A 3SQ9A 3UU6A 4D01A 5TVCA 2WNJA 4IREA 2WZYA 4Z91A 4HFBA 2XYSA 2ZJVA 2YKSA 4ILAA 4ILCA 5JMEA 3RI5A 3U8KA 3JAFA 2XQ7A 4A97A 3C84A 4HFIA 3ZDHA 2BJ0A 4ALXA 2Y7YA 4ZZCA 2BYRA 2W8GA 4BQTA 2WNLA 5AINA 5KE4A 3WTIA 5IUXA 3U8MA 4F8HA 2YMEA 5CO5A 3U8JA 4ZJTA 4Z90A 1I9BA 3WTNA 4AFHA 4HFEA 3P50A 5AFJA 5L47A 2XNTA 3RQUA 2XQAA 4IL9A 2BYSA 2C9TA 4UM1A 3PMZA 4UXUA 4BFQA 4ZK4A 3WTJA 2BYQA 3WTKA 3UQ7A 3U8NA 5J0ZA 2X00A 2BR7A 4NZBA 4B5DA 2XNVA 5J5GA 3TLUA 4A98A 5AFMA 4ZZBA 3ZKRA 5HEUA 3JADA 2PGZA 5AFLA 4FRRA 4TWFA 4WV9A 4UM3S 3SQ6A 2YOEA 2WNCA 2Y54A 4XK9A 2BG9A 5AFNA 5L4EA 3WTMA 3IGQA 2PH9A 5HEJA 4AFTA 4LMLA 5HEGA 2BR8A 3C79A 3EAMA 5CFBA 5BW2A 3LSVA 5HCJA 2BG9E 3EI0A 4IL4A 2UZ6A 3UU5A 5HEHA 4QAAA 5AFHA 1UV6A 4ZRUA 3JAEA 5BRXA 5HEOA 2QC1B 5SYOA 3UUBA 3TLTA 3GUAA 4HQPA 4HFHA 5HCMA 4PIRA 2XQ4A 2VL0A 2XZ6A 4X5TA 4UM3A 3UQ4A 5L4HA 2BYNA 3SIOA 2XQ9A 2BYPA 2YMDA 1UX2A 3ZDGA 3RIFA 3P4WA
chains in the Genus database with same CATH topology
5BP0A 3WIPA 3U8LA 3WTOA 2BG9C 4ZJSA 3TLWA 4ZK1A 1UW6A 2Y56A 4QH4A 2XQ6A 4NPPA 5J5IA 4ILBA 4COFA 2XNUA 2WN9A 2XQ3A 3UU4A 3WTHA 5J5HA 4QH5A 3TLVA 5LG3A 4TWDA 4XHEA 4ZR6A 4QH1A 5AFMB 2W8FA 4UY2A 4TWHA 4EZ1A 3PEOA 5LXBA 2XQ5A 4AFGA 2YN6A 4DBMA 4TNVA 4QACA 3SH1A 4LMJA 3RQWA 3UU3A 3WTLA 2XQ8A 2BG9B 3RIAA 4UM3P 3RHWA 3T4MA 2X00D 5FJVA 4LMKA 3UU8A 2Y57A 2Y58A 3EHZA 4HFCA 5KZUA 5AFKA 5J5FA 2ZJUA 4QABA 3TLSA 4HFDA 2XYTA 4TNWA 2XZ5A 3SQ9A 3UU6A 4D01A 5TVCA 2WNJA 4IREA 2WZYA 4Z91A 4HFBA 2XYSA 2ZJVA 2YKSA 4ILAA 4ILCA 5JMEA 3RI5A 3U8KA 3JAFA 2XQ7A 4A97A 3C84A 4HFIA 3ZDHA 2BJ0A 4ALXA 2Y7YA 4ZZCA 2BYRA 2W8GA 4BQTA 2WNLA 5AINA 5KE4A 3WTIA 5IUXA 3U8MA 4F8HA 2YMEA 5CO5A 3U8JA 4ZJTA 4Z90A 1I9BA 3WTNA 4AFHA 4HFEA 3P50A 5AFJA 5L47A 2XNTA 3RQUA 2XQAA 4IL9A 2BYSA 2C9TA 4UM1A 3PMZA 4UXUA 4BFQA 4ZK4A 3WTJA 2BYQA 3WTKA 3UQ7A 3U8NA 5J0ZA 2X00A 2BR7A 4NZBA 4B5DA 2XNVA 5J5GA 3TLUA 4A98A 5AFMA 4ZZBA 3ZKRA 5HEUA 3JADA 2PGZA 5AFLA 4FRRA 4TWFA 4WV9A 4UM3S 3SQ6A 2YOEA 2WNCA 2Y54A 4XK9A 2BG9A 5AFNA 5L4EA 3WTMA 3IGQA 2PH9A 5HEJA 4AFTA 4LMLA 5HEGA 2BR8A 3C79A 3EAMA 5CFBA 5BW2A 3LSVA 5HCJA 2BG9E 3EI0A 4IL4A 2UZ6A 3UU5A 5HEHA 4QAAA 5AFHA 1UV6A 4ZRUA 3JAEA 5BRXA 5HEOA 2QC1B 5SYOA 3UUBA 3TLTA 3GUAA 4HQPA 4HFHA 5HCMA 4PIRA 2XQ4A 2VL0A 2XZ6A 4X5TA 4UM3A 3UQ4A 5L4HA 2BYNA 3SIOA 2XQ9A 2BYPA 2YMDA 1UX2A 3ZDGA 3RIFA 3P4WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5BP0 A;  3WIP A;  3U8L A;  3WTO A;  2BG9 C;  4ZJS A;  3TLW A;  4ZK1 A;  1UW6 A;  2Y56 A;  4QH4 A;  2XQ6 A;  4NPP A;  5J5I A;  4ILB A;  4COF A;  2XNU A;  2WN9 A;  2XQ3 A;  3UU4 A;  3WTH A;  5J5H A;  4QH5 A;  3TLV A;  5LG3 A;  4TWD A;  4XHE A;  4ZR6 A;  4QH1 A;  5AFM B;  2W8F A;  4UY2 A;  4TWH A;  4EZ1 A;  3PEO A;  5LXB A;  2XQ5 A;  4AFG A;  2YN6 A;  4DBM A;  4TNV A;  4QAC A;  3SH1 A;  4LMJ A;  3RQW A;  3UU3 A;  3WTL A;  2XQ8 A;  2BG9 B;  3RIA A;  4UM3 P;  3RHW A;  3T4M A;  2X00 D;  5FJV A;  4LMK A;  3UU8 A;  2Y57 A;  2Y58 A;  3EHZ A;  4HFC A;  5KZU A;  5AFK A;  5J5F A;  2ZJU A;  4QAB A;  3TLS A;  4HFD A;  2XYT A;  4TNW A;  2XZ5 A;  3SQ9 A;  3UU6 A;  4D01 A;  5TVC A;  2WNJ A;  4IRE A;  2WZY A;  4Z91 A;  4HFB A;  2XYS A;  2ZJV A;  2YKS A;  4ILA A;  4ILC A;  5JME A;  3RI5 A;  3U8K A;  3JAF A;  2XQ7 A;  4A97 A;  3C84 A;  4HFI A;  3ZDH A;  2BJ0 A;  4ALX A;  2Y7Y A;  4ZZC A;  2BYR A;  2W8G A;  4BQT A;  2WNL A;  5AIN A;  5KE4 A;  3WTI A;  5IUX A;  3U8M A;  4F8H A;  2YME A;  5CO5 A;  3U8J A;  4ZJT A;  4Z90 A;  1I9B A;  3WTN A;  4AFH A;  4HFE A;  3P50 A;  5AFJ A;  5L47 A;  2XNT A;  3RQU A;  2XQA A;  4IL9 A;  2BYS A;  2C9T A;  4UM1 A;  3PMZ A;  4UXU A;  4BFQ A;  4ZK4 A;  3WTJ A;  2BYQ A;  3WTK A;  3UQ7 A;  3U8N A;  5J0Z A;  2X00 A;  2BR7 A;  4NZB A;  4B5D A;  2XNV A;  5J5G A;  3TLU A;  4A98 A;  5AFM A;  4ZZB A;  3ZKR A;  5HEU A;  3JAD A;  2PGZ A;  5AFL A;  4FRR A;  4TWF A;  4WV9 A;  4UM3 S;  3SQ6 A;  2YOE A;  2WNC A;  2Y54 A;  4XK9 A;  2BG9 A;  5AFN A;  5L4E A;  3WTM A;  3IGQ A;  2PH9 A;  5HEJ A;  4AFT A;  4LML A;  5HEG A;  2BR8 A;  3C79 A;  3EAM A;  5CFB A;  5BW2 A;  3LSV A;  5HCJ A;  2BG9 E;  3EI0 A;  4IL4 A;  2UZ6 A;  3UU5 A;  5HEH A;  4QAA A;  5AFH A;  1UV6 A;  4ZRU A;  3JAE A;  5BRX A;  5HEO A;  2QC1 B;  5SYO A;  3UUB A;  3TLT A;  3GUA A;  4HQP A;  4HFH A;  5HCM A;  4PIR A;  2XQ4 A;  2VL0 A;  2XZ6 A;  4X5T A;  4UM3 A;  3UQ4 A;  5L4H A;  2BYN A;  3SIO A;  2XQ9 A;  2BYP A;  2YMD A;  1UX2 A;  3ZDG A;  3RIF A;  3P4W A; 
#chains in the Genus database with same CATH topology
 5BP0 A;  3WIP A;  3U8L A;  3WTO A;  2BG9 C;  4ZJS A;  3TLW A;  4ZK1 A;  1UW6 A;  2Y56 A;  4QH4 A;  2XQ6 A;  4NPP A;  5J5I A;  4ILB A;  4COF A;  2XNU A;  2WN9 A;  2XQ3 A;  3UU4 A;  3WTH A;  5J5H A;  4QH5 A;  3TLV A;  5LG3 A;  4TWD A;  4XHE A;  4ZR6 A;  4QH1 A;  5AFM B;  2W8F A;  4UY2 A;  4TWH A;  4EZ1 A;  3PEO A;  5LXB A;  2XQ5 A;  4AFG A;  2YN6 A;  4DBM A;  4TNV A;  4QAC A;  3SH1 A;  4LMJ A;  3RQW A;  3UU3 A;  3WTL A;  2XQ8 A;  2BG9 B;  3RIA A;  4UM3 P;  3RHW A;  3T4M A;  2X00 D;  5FJV A;  4LMK A;  3UU8 A;  2Y57 A;  2Y58 A;  3EHZ A;  4HFC A;  5KZU A;  5AFK A;  5J5F A;  2ZJU A;  4QAB A;  3TLS A;  4HFD A;  2XYT A;  4TNW A;  2XZ5 A;  3SQ9 A;  3UU6 A;  4D01 A;  5TVC A;  2WNJ A;  4IRE A;  2WZY A;  4Z91 A;  4HFB A;  2XYS A;  2ZJV A;  2YKS A;  4ILA A;  4ILC A;  5JME A;  3RI5 A;  3U8K A;  3JAF A;  2XQ7 A;  4A97 A;  3C84 A;  4HFI A;  3ZDH A;  2BJ0 A;  4ALX A;  2Y7Y A;  4ZZC A;  2BYR A;  2W8G A;  4BQT A;  2WNL A;  5AIN A;  5KE4 A;  3WTI A;  5IUX A;  3U8M A;  4F8H A;  2YME A;  5CO5 A;  3U8J A;  4ZJT A;  4Z90 A;  1I9B A;  3WTN A;  4AFH A;  4HFE A;  3P50 A;  5AFJ A;  5L47 A;  2XNT A;  3RQU A;  2XQA A;  4IL9 A;  2BYS A;  2C9T A;  4UM1 A;  3PMZ A;  4UXU A;  4BFQ A;  4ZK4 A;  3WTJ A;  2BYQ A;  3WTK A;  3UQ7 A;  3U8N A;  5J0Z A;  2X00 A;  2BR7 A;  4NZB A;  4B5D A;  2XNV A;  5J5G A;  3TLU A;  4A98 A;  5AFM A;  4ZZB A;  3ZKR A;  5HEU A;  3JAD A;  2PGZ A;  5AFL A;  4FRR A;  4TWF A;  4WV9 A;  4UM3 S;  3SQ6 A;  2YOE A;  2WNC A;  2Y54 A;  4XK9 A;  2BG9 A;  5AFN A;  5L4E A;  3WTM A;  3IGQ A;  2PH9 A;  5HEJ A;  4AFT A;  4LML A;  5HEG A;  2BR8 A;  3C79 A;  3EAM A;  5CFB A;  5BW2 A;  3LSV A;  5HCJ A;  2BG9 E;  3EI0 A;  4IL4 A;  2UZ6 A;  3UU5 A;  5HEH A;  4QAA A;  5AFH A;  1UV6 A;  4ZRU A;  3JAE A;  5BRX A;  5HEO A;  2QC1 B;  5SYO A;  3UUB A;  3TLT A;  3GUA A;  4HQP A;  4HFH A;  5HCM A;  4PIR A;  2XQ4 A;  2VL0 A;  2XZ6 A;  4X5T A;  4UM3 A;  3UQ4 A;  5L4H A;  2BYN A;  3SIO A;  2XQ9 A;  2BYP A;  2YMD A;  1UX2 A;  3ZDG A;  3RIF A;  3P4W A; 
#chains in the Genus database with same CATH homology
 5BP0 A;  3WIP A;  3U8L A;  3WTO A;  2BG9 C;  4ZJS A;  3TLW A;  4ZK1 A;  1UW6 A;  2Y56 A;  4QH4 A;  2XQ6 A;  4NPP A;  5J5I A;  4ILB A;  4COF A;  2XNU A;  2WN9 A;  2XQ3 A;  3UU4 A;  3WTH A;  5J5H A;  4QH5 A;  3TLV A;  5LG3 A;  4TWD A;  4XHE A;  4ZR6 A;  4QH1 A;  5AFM B;  2W8F A;  4UY2 A;  4TWH A;  4EZ1 A;  3PEO A;  5LXB A;  2XQ5 A;  4AFG A;  2YN6 A;  4DBM A;  4TNV A;  4QAC A;  3SH1 A;  4LMJ A;  3RQW A;  3UU3 A;  3WTL A;  2XQ8 A;  2BG9 B;  3RIA A;  4UM3 P;  3RHW A;  3T4M A;  2X00 D;  5FJV A;  4LMK A;  3UU8 A;  2Y57 A;  2Y58 A;  3EHZ A;  4HFC A;  5KZU A;  5AFK A;  5J5F A;  2ZJU A;  4QAB A;  3TLS A;  4HFD A;  2XYT A;  4TNW A;  2XZ5 A;  3SQ9 A;  3UU6 A;  4D01 A;  5TVC A;  2WNJ A;  4IRE A;  2WZY A;  4Z91 A;  4HFB A;  2XYS A;  2ZJV A;  2YKS A;  4ILA A;  4ILC A;  5JME A;  3RI5 A;  3U8K A;  3JAF A;  2XQ7 A;  4A97 A;  3C84 A;  4HFI A;  3ZDH A;  2BJ0 A;  4ALX A;  2Y7Y A;  4ZZC A;  2BYR A;  2W8G A;  4BQT A;  2WNL A;  5AIN A;  5KE4 A;  3WTI A;  5IUX A;  3U8M A;  4F8H A;  2YME A;  5CO5 A;  3U8J A;  4ZJT A;  4Z90 A;  1I9B A;  3WTN A;  4AFH A;  4HFE A;  3P50 A;  5AFJ A;  5L47 A;  2XNT A;  3RQU A;  2XQA A;  4IL9 A;  2BYS A;  2C9T A;  4UM1 A;  3PMZ A;  4UXU A;  4BFQ A;  4ZK4 A;  3WTJ A;  2BYQ A;  3WTK A;  3UQ7 A;  3U8N A;  5J0Z A;  2X00 A;  2BR7 A;  4NZB A;  4B5D A;  2XNV A;  5J5G A;  3TLU A;  4A98 A;  5AFM A;  4ZZB A;  3ZKR A;  5HEU A;  3JAD A;  2PGZ A;  5AFL A;  4FRR A;  4TWF A;  4WV9 A;  4UM3 S;  3SQ6 A;  2YOE A;  2WNC A;  2Y54 A;  4XK9 A;  2BG9 A;  5AFN A;  5L4E A;  3WTM A;  3IGQ A;  2PH9 A;  5HEJ A;  4AFT A;  4LML A;  5HEG A;  2BR8 A;  3C79 A;  3EAM A;  5CFB A;  5BW2 A;  3LSV A;  5HCJ A;  2BG9 E;  3EI0 A;  4IL4 A;  2UZ6 A;  3UU5 A;  5HEH A;  4QAA A;  5AFH A;  1UV6 A;  4ZRU A;  3JAE A;  5BRX A;  5HEO A;  2QC1 B;  5SYO A;  3UUB A;  3TLT A;  3GUA A;  4HQP A;  4HFH A;  5HCM A;  4PIR A;  2XQ4 A;  2VL0 A;  2XZ6 A;  4X5T A;  4UM3 A;  3UQ4 A;  5L4H A;  2BYN A;  3SIO A;  2XQ9 A;  2BYP A;  2YMD A;  1UX2 A;  3ZDG A;  3RIF A;  3P4W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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