The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
58
|
sequence length |
216
|
structure length |
216
|
Chain Sequence |
YKDDDDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Marine Macrocyclic Imines, Pinnatoxins A and G: Structural Determinants and Functional Properties to Distinguish Neuronal alpha 7 from Muscle alpha 12 beta gamma delta nAChRs.
pubmed doi rcsb |
| molecule keywords |
Soluble acetylcholine receptor
|
| molecule tags |
Acetylcholine-binding protein
|
| source organism |
Aplysia californica
|
| total genus |
58
|
| structure length |
216
|
| sequence length |
216
|
| chains with identical sequence |
B, C, D, E, F, G, H, I, J
|
| ec nomenclature | |
| pdb deposition date | 2015-01-05 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF02931 | Neur_chan_LBD | Neurotransmitter-gated ion-channel ligand binding domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Beta | Distorted Sandwich | Acetylcholine Binding Protein; Chain: A, | Neurotransmitter-gated ion-channel ligand-binding domain |
#chains in the Genus database with same CATH superfamily 4UM3 S; 1UV6 A; 2WNL A; 2ZJV A; 3EHZ A; 4UM3 P; 4COF A; 3P4W A; 3JAF A; 4BQT A; 2WNJ A; 2X00 A; 3PEO A; 4QAC A; 3LSV A; 4HFB A; 4B5D A; 4ILC A; 4ZK1 A; 3WTH A; 5HCM A; 4IL4 A; 4IRE A; 5HEO A; 5AFN A; 2XQ6 A; 4QAB A; 4UM1 A; 2Y7Y A; 3UU6 A; 3JAE A; 5HCJ A; 2C9T A; 2BYN A; 2XNT A; 5CFB A; 4Z91 A; 3EI0 A; 3WIP A; 2Y57 A; 2YN6 A; 2W8G A; 3U8N A; 2YME A; 4LMJ A; 5HEH A; 3SIO A; 2BG9 B; 4LML A; 5AFH A; 3RQU A; 4ILB A; 3U8J A; 4HFD A; 4QH4 A; 3WTI A; 5L4E A; 3ZKR A; 5AFK A; 2BG9 A; 4ZK4 A; 4QAA A; 2BR7 A; 3U8L A; 4PIR A; 2XNV A; 3SQ6 A; 2XZ5 A; 4ZZB A; 4IL9 A; 2BYP A; 4ZZC A; 2YKS A; 3TLW A; 4TNV A; 4NZB A; 3RIA A; 4ALX A; 4AFT A; 4BFQ A; 2WNC A; 4ZR6 A; 4AFH A; 4UXU A; 3RQW A; 2XQ8 A; 3WTK A; 3WTN A; 3SH1 A; 5KE4 A; 5LG3 A; 3TLT A; 2XYT A; 4FRR A; 5SYO A; 3SQ9 A; 2XQ7 A; 3JAD A; 5AFM B; 3TLV A; 5BRX A; 3TLS A; 2PGZ A; 2X00 D; 4ZRU A; 4HQP A; 3WTM A; 4X5T A; 2Y56 A; 3UUB A; 5AFM A; 3UU5 A; 4EZ1 A; 3UU3 A; 4A98 A; 2BYR A; 3RIF A; 5J5H A; 2BR8 A; 4HFH A; 2YOE A; 3T4M A; 4A97 A; 2XYS A; 2PH9 A; 2Y54 A; 2XQ4 A; 3C84 A; 3WTO A; 2XZ6 A; 1UX2 A; 5CO5 A; 3RI5 A; 5HEJ A; 3EAM A; 2WN9 A; 5J5G A; 4D01 A; 4XK9 A; 5LXB A; 2XQA A; 2BYS A; 5J5F A; 4ZJT A; 5J5I A; 4HFC A; 3U8K A; 2VL0 A; 4ZJS A; 2WZY A; 3TLU A; 2UZ6 A; 1I9B A; 2BG9 E; 2BG9 C; 3ZDH A; 3GUA A; 2BJ0 A; 4TWD A; 2XNU A; 4TWH A; 3UQ4 A; 3PMZ A; 5HEG A; 2Y58 A; 2XQ9 A; 2ZJU A; 3P50 A; 4HFI A; 5J0Z A; 4TNW A; 3UU8 A; 2YMD A; 4LMK A; 5AIN A; 5KZU A; 5L47 A; 5BP0 A; 4QH1 A; 5AFJ A; 3UU4 A; 4NPP A; 5BW2 A; 5JME A; 4F8H A; 2XQ3 A; 4HFE A; 3UQ7 A; 4AFG A; 4TWF A; 4UY2 A; 4XHE A; 2QC1 B; 5TVC A; 4Z90 A; 3ZDG A; 2W8F A; 4ILA A; 5L4H A; 3RHW A; 3C79 A; 3WTJ A; 4DBM A; 3IGQ A; 3WTL A; 5IUX A; 5HEU A; 4WV9 A; 2BYQ A; 4UM3 A; 3U8M A; 5FJV A; 1UW6 A; 2XQ5 A; 4QH5 A; 5AFL A; #chains in the Genus database with same CATH topology 4UM3 S; 1UV6 A; 2WNL A; 2ZJV A; 3EHZ A; 4UM3 P; 4COF A; 3P4W A; 3JAF A; 4BQT A; 2WNJ A; 2X00 A; 3PEO A; 4QAC A; 3LSV A; 4HFB A; 4B5D A; 4ILC A; 4ZK1 A; 3WTH A; 5HCM A; 4IL4 A; 4IRE A; 5HEO A; 5AFN A; 2XQ6 A; 4QAB A; 4UM1 A; 2Y7Y A; 3UU6 A; 3JAE A; 5HCJ A; 2C9T A; 2BYN A; 2XNT A; 5CFB A; 4Z91 A; 3EI0 A; 3WIP A; 2Y57 A; 2YN6 A; 2W8G A; 3U8N A; 2YME A; 4LMJ A; 5HEH A; 3SIO A; 2BG9 B; 4LML A; 5AFH A; 3RQU A; 4ILB A; 3U8J A; 4HFD A; 4QH4 A; 3WTI A; 5L4E A; 3ZKR A; 5AFK A; 2BG9 A; 4ZK4 A; 4QAA A; 2BR7 A; 3U8L A; 4PIR A; 2XNV A; 3SQ6 A; 2XZ5 A; 4ZZB A; 4IL9 A; 2BYP A; 4ZZC A; 2YKS A; 3TLW A; 4TNV A; 4NZB A; 3RIA A; 4ALX A; 4AFT A; 4BFQ A; 2WNC A; 4ZR6 A; 4AFH A; 4UXU A; 3RQW A; 2XQ8 A; 3WTK A; 3WTN A; 3SH1 A; 5KE4 A; 5LG3 A; 3TLT A; 2XYT A; 4FRR A; 5SYO A; 3SQ9 A; 2XQ7 A; 3JAD A; 5AFM B; 3TLV A; 5BRX A; 3TLS A; 2PGZ A; 2X00 D; 4ZRU A; 4HQP A; 3WTM A; 4X5T A; 2Y56 A; 3UUB A; 5AFM A; 3UU5 A; 4EZ1 A; 3UU3 A; 4A98 A; 2BYR A; 3RIF A; 5J5H A; 2BR8 A; 4HFH A; 2YOE A; 3T4M A; 4A97 A; 2XYS A; 2PH9 A; 2Y54 A; 2XQ4 A; 3C84 A; 3WTO A; 2XZ6 A; 1UX2 A; 5CO5 A; 3RI5 A; 5HEJ A; 3EAM A; 2WN9 A; 5J5G A; 4D01 A; 4XK9 A; 5LXB A; 2XQA A; 2BYS A; 5J5F A; 4ZJT A; 5J5I A; 4HFC A; 3U8K A; 2VL0 A; 4ZJS A; 2WZY A; 3TLU A; 2UZ6 A; 1I9B A; 2BG9 E; 2BG9 C; 3ZDH A; 3GUA A; 2BJ0 A; 4TWD A; 2XNU A; 4TWH A; 3UQ4 A; 3PMZ A; 5HEG A; 2Y58 A; 2XQ9 A; 2ZJU A; 3P50 A; 4HFI A; 5J0Z A; 4TNW A; 3UU8 A; 2YMD A; 4LMK A; 5AIN A; 5KZU A; 5L47 A; 5BP0 A; 4QH1 A; 5AFJ A; 3UU4 A; 4NPP A; 5BW2 A; 5JME A; 4F8H A; 2XQ3 A; 4HFE A; 3UQ7 A; 4AFG A; 4TWF A; 4UY2 A; 4XHE A; 2QC1 B; 5TVC A; 4Z90 A; 3ZDG A; 2W8F A; 4ILA A; 5L4H A; 3RHW A; 3C79 A; 3WTJ A; 4DBM A; 3IGQ A; 3WTL A; 5IUX A; 5HEU A; 4WV9 A; 2BYQ A; 4UM3 A; 3U8M A; 5FJV A; 1UW6 A; 2XQ5 A; 4QH5 A; 5AFL A; #chains in the Genus database with same CATH homology 4UM3 S; 1UV6 A; 2WNL A; 2ZJV A; 3EHZ A; 4UM3 P; 4COF A; 3P4W A; 3JAF A; 4BQT A; 2WNJ A; 2X00 A; 3PEO A; 4QAC A; 3LSV A; 4HFB A; 4B5D A; 4ILC A; 4ZK1 A; 3WTH A; 5HCM A; 4IL4 A; 4IRE A; 5HEO A; 5AFN A; 2XQ6 A; 4QAB A; 4UM1 A; 2Y7Y A; 3UU6 A; 3JAE A; 5HCJ A; 2C9T A; 2BYN A; 2XNT A; 5CFB A; 4Z91 A; 3EI0 A; 3WIP A; 2Y57 A; 2YN6 A; 2W8G A; 3U8N A; 2YME A; 4LMJ A; 5HEH A; 3SIO A; 2BG9 B; 4LML A; 5AFH A; 3RQU A; 4ILB A; 3U8J A; 4HFD A; 4QH4 A; 3WTI A; 5L4E A; 3ZKR A; 5AFK A; 2BG9 A; 4ZK4 A; 4QAA A; 2BR7 A; 3U8L A; 4PIR A; 2XNV A; 3SQ6 A; 2XZ5 A; 4ZZB A; 4IL9 A; 2BYP A; 4ZZC A; 2YKS A; 3TLW A; 4TNV A; 4NZB A; 3RIA A; 4ALX A; 4AFT A; 4BFQ A; 2WNC A; 4ZR6 A; 4AFH A; 4UXU A; 3RQW A; 2XQ8 A; 3WTK A; 3WTN A; 3SH1 A; 5KE4 A; 5LG3 A; 3TLT A; 2XYT A; 4FRR A; 5SYO A; 3SQ9 A; 2XQ7 A; 3JAD A; 5AFM B; 3TLV A; 5BRX A; 3TLS A; 2PGZ A; 2X00 D; 4ZRU A; 4HQP A; 3WTM A; 4X5T A; 2Y56 A; 3UUB A; 5AFM A; 3UU5 A; 4EZ1 A; 3UU3 A; 4A98 A; 2BYR A; 3RIF A; 5J5H A; 2BR8 A; 4HFH A; 2YOE A; 3T4M A; 4A97 A; 2XYS A; 2PH9 A; 2Y54 A; 2XQ4 A; 3C84 A; 3WTO A; 2XZ6 A; 1UX2 A; 5CO5 A; 3RI5 A; 5HEJ A; 3EAM A; 2WN9 A; 5J5G A; 4D01 A; 4XK9 A; 5LXB A; 2XQA A; 2BYS A; 5J5F A; 4ZJT A; 5J5I A; 4HFC A; 3U8K A; 2VL0 A; 4ZJS A; 2WZY A; 3TLU A; 2UZ6 A; 1I9B A; 2BG9 E; 2BG9 C; 3ZDH A; 3GUA A; 2BJ0 A; 4TWD A; 2XNU A; 4TWH A; 3UQ4 A; 3PMZ A; 5HEG A; 2Y58 A; 2XQ9 A; 2ZJU A; 3P50 A; 4HFI A; 5J0Z A; 4TNW A; 3UU8 A; 2YMD A; 4LMK A; 5AIN A; 5KZU A; 5L47 A; 5BP0 A; 4QH1 A; 5AFJ A; 3UU4 A; 4NPP A; 5BW2 A; 5JME A; 4F8H A; 2XQ3 A; 4HFE A; 3UQ7 A; 4AFG A; 4TWF A; 4UY2 A; 4XHE A; 2QC1 B; 5TVC A; 4Z90 A; 3ZDG A; 2W8F A; 4ILA A; 5L4H A; 3RHW A; 3C79 A; 3WTJ A; 4DBM A; 3IGQ A; 3WTL A; 5IUX A; 5HEU A; 4WV9 A; 2BYQ A; 4UM3 A; 3U8M A; 5FJV A; 1UW6 A; 2XQ5 A; 4QH5 A; 5AFL A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
