2BYSA

Crystal structure of achbp from aplysia californica in complex with lobeline
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
207
structure length
205
Chain Sequence
SQANLMRLKSDLFNRSYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Aplysia Achbp Complexes with Nicotinic Agonists and Antagonists Reveal Distinctive Binding Interfaces and Conformations.
pubmed doi rcsb
molecule tags Receptor
source organism Aplysia californica
molecule keywords ACETYLCHOLINE-BINDING PROTEIN
total genus 48
structure length 205
sequence length 207
chains with identical sequence B, C, D, E, F, G, H, I, J
ec nomenclature
pdb deposition date 2005-08-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 2bysA00
5AFNA 2YMDA 2VL0A 2Y54A 2BG9A 5L4HA 3U8LA 2W8GA 4QH1A 5AFJA 4LMLA 2Y7YA 3ZDHA 3ZKRA 2ZJUA 3SH1A 3EHZA 2XQAA 2BYPA 5AFLA 5HEGA 4ALXA 5HEUA 2Y57A 2WNJA 3PMZA 3RIFA 4WV9A 3WTHA 4QH4A 5J0ZA 3RQUA 4ILCA 2BG9B 4QAAA 3JAEA 3SQ9A 4X5TA 4ILBA 3RIAA 2UZ6A 3TLWA 4ZR6A 5FJVA 4TNVA 5BP0A 5J5HA 3LSVA 2XYSA 3JAFA 4HFIA 4LMKA 5HCMA 4ZZBA 5JMEA 2X00A 3U8JA 2Y58A 2Y56A 4HFEA 4IREA 2BG9C 4TWFA 4UM3A 4UY2A 5L4EA 2YKSA 3WTMA 1UW6A 3SIOA 3EAMA 3UU6A 4UM3S 5J5IA 2QC1B 2XNVA 5BRXA 2XQ6A 2WN9A 5CFBA 2XQ3A 2XQ5A 3IGQA 3SQ6A 1UX2A 3UU4A 5TVCA 4A98A 4FRRA 3WTJA 3C84A 4BQTA 4NPPA 3JADA 2PH9A 2XQ7A 2BYNA 3RHWA 2XZ5A 5L47A 4IL9A 4ZRUA 3TLSA 2BR8A 3WTOA 5HEHA 3TLTA 4HFHA 4TWHA 2XYTA 3UU3A 3RI5A 2BYSA 4IL4A 3UU8A 5IUXA 4F8HA 2XZ6A 3C79A 4HFBA 3WTLA 4BFQA 4EZ1A 3UU5A 5SYOA 5AFHA 2XQ8A 4HFDA 4UM1A 2X00D 2ZJVA 4QACA 4PIRA 5AFMA 3GUAA 4TWDA 5LXBA 3UQ7A 4QABA 2BYQA 4ILAA 4TNWA 5AINA 4ZK4A 4NZBA 2BJ0A 4AFGA 4AFTA 2YN6A 4ZZCA 4UM3P 5CO5A 3U8NA 3WIPA 3TLVA 3U8KA 4XHEA 4ZK1A 4COFA 2YMEA 3T4MA 3WTIA 2XNUA 3WTKA 4HQPA 5HCJA 2WZYA 5BW2A 3PEOA 3UQ4A 4AFHA 3U8MA 5HEJA 4QH5A 4B5DA 5AFMB 3TLUA 3P4WA 4D01A 2XQ4A 2BG9E 2W8FA 5KE4A 5HEOA 4Z91A 4HFCA 3ZDGA 4A97A 5LG3A 2PGZA 4ZJSA 4ZJTA 5AFKA 2WNLA 2WNCA 2XQ9A 5J5GA 3UUBA 4Z90A 5KZUA 2C9TA 2BYRA 2YOEA 3P50A 4LMJA 4XK9A 2XNTA 3RQWA 4DBMA 5J5FA 1I9BA 4UXUA 3EI0A 2BR7A 1UV6A 3WTNA
chains in the Genus database with same CATH superfamily
5AFNA 2YMDA 2VL0A 2Y54A 2BG9A 5L4HA 3U8LA 2W8GA 4QH1A 5AFJA 4LMLA 2Y7YA 3ZDHA 3ZKRA 2ZJUA 3SH1A 3EHZA 2XQAA 2BYPA 5AFLA 5HEGA 4ALXA 5HEUA 2Y57A 2WNJA 3PMZA 3RIFA 4WV9A 3WTHA 4QH4A 5J0ZA 3RQUA 4ILCA 2BG9B 4QAAA 3JAEA 3SQ9A 4X5TA 4ILBA 3RIAA 2UZ6A 3TLWA 4ZR6A 5FJVA 4TNVA 5BP0A 5J5HA 3LSVA 2XYSA 3JAFA 4HFIA 4LMKA 5HCMA 4ZZBA 5JMEA 2X00A 3U8JA 2Y58A 2Y56A 4HFEA 4IREA 2BG9C 4TWFA 4UM3A 4UY2A 5L4EA 2YKSA 3WTMA 1UW6A 3SIOA 3EAMA 3UU6A 4UM3S 5J5IA 2QC1B 2XNVA 5BRXA 2XQ6A 2WN9A 5CFBA 2XQ3A 2XQ5A 3IGQA 3SQ6A 1UX2A 3UU4A 5TVCA 4A98A 4FRRA 3WTJA 3C84A 4BQTA 4NPPA 3JADA 2PH9A 2XQ7A 2BYNA 3RHWA 2XZ5A 5L47A 4IL9A 4ZRUA 3TLSA 2BR8A 3WTOA 5HEHA 3TLTA 4HFHA 4TWHA 2XYTA 3UU3A 3RI5A 2BYSA 4IL4A 3UU8A 5IUXA 4F8HA 2XZ6A 3C79A 4HFBA 3WTLA 4BFQA 4EZ1A 3UU5A 5SYOA 5AFHA 2XQ8A 4HFDA 4UM1A 2X00D 2ZJVA 4QACA 4PIRA 5AFMA 3GUAA 4TWDA 5LXBA 3UQ7A 4QABA 2BYQA 4ILAA 4TNWA 5AINA 4ZK4A 4NZBA 2BJ0A 4AFGA 4AFTA 2YN6A 4ZZCA 4UM3P 5CO5A 3U8NA 3WIPA 3TLVA 3U8KA 4XHEA 4ZK1A 4COFA 2YMEA 3T4MA 3WTIA 2XNUA 3WTKA 4HQPA 5HCJA 2WZYA 5BW2A 3PEOA 3UQ4A 4AFHA 3U8MA 5HEJA 4QH5A 4B5DA 5AFMB 3TLUA 3P4WA 4D01A 2XQ4A 2BG9E 2W8FA 5KE4A 5HEOA 4Z91A 4HFCA 3ZDGA 4A97A 5LG3A 2PGZA 4ZJSA 4ZJTA 5AFKA 2WNLA 2WNCA 2XQ9A 5J5GA 3UUBA 4Z90A 5KZUA 2C9TA 2BYRA 2YOEA 3P50A 4LMJA 4XK9A 2XNTA 3RQWA 4DBMA 5J5FA 1I9BA 4UXUA 3EI0A 2BR7A 1UV6A 3WTNA
chains in the Genus database with same CATH topology
5AFNA 2YMDA 2VL0A 2Y54A 2BG9A 5L4HA 3U8LA 2W8GA 4QH1A 5AFJA 4LMLA 2Y7YA 3ZDHA 3ZKRA 2ZJUA 3SH1A 3EHZA 2XQAA 2BYPA 5AFLA 5HEGA 4ALXA 5HEUA 2Y57A 2WNJA 3PMZA 3RIFA 4WV9A 3WTHA 4QH4A 5J0ZA 3RQUA 4ILCA 2BG9B 4QAAA 3JAEA 3SQ9A 4X5TA 4ILBA 3RIAA 2UZ6A 3TLWA 4ZR6A 5FJVA 4TNVA 5BP0A 5J5HA 3LSVA 2XYSA 3JAFA 4HFIA 4LMKA 5HCMA 4ZZBA 5JMEA 2X00A 3U8JA 2Y58A 2Y56A 4HFEA 4IREA 2BG9C 4TWFA 4UM3A 4UY2A 5L4EA 2YKSA 3WTMA 1UW6A 3SIOA 3EAMA 3UU6A 4UM3S 5J5IA 2QC1B 2XNVA 5BRXA 2XQ6A 2WN9A 5CFBA 2XQ3A 2XQ5A 3IGQA 3SQ6A 1UX2A 3UU4A 5TVCA 4A98A 4FRRA 3WTJA 3C84A 4BQTA 4NPPA 3JADA 2PH9A 2XQ7A 2BYNA 3RHWA 2XZ5A 5L47A 4IL9A 4ZRUA 3TLSA 2BR8A 3WTOA 5HEHA 3TLTA 4HFHA 4TWHA 2XYTA 3UU3A 3RI5A 2BYSA 4IL4A 3UU8A 5IUXA 4F8HA 2XZ6A 3C79A 4HFBA 3WTLA 4BFQA 4EZ1A 3UU5A 5SYOA 5AFHA 2XQ8A 4HFDA 4UM1A 2X00D 2ZJVA 4QACA 4PIRA 5AFMA 3GUAA 4TWDA 5LXBA 3UQ7A 4QABA 2BYQA 4ILAA 4TNWA 5AINA 4ZK4A 4NZBA 2BJ0A 4AFGA 4AFTA 2YN6A 4ZZCA 4UM3P 5CO5A 3U8NA 3WIPA 3TLVA 3U8KA 4XHEA 4ZK1A 4COFA 2YMEA 3T4MA 3WTIA 2XNUA 3WTKA 4HQPA 5HCJA 2WZYA 5BW2A 3PEOA 3UQ4A 4AFHA 3U8MA 5HEJA 4QH5A 4B5DA 5AFMB 3TLUA 3P4WA 4D01A 2XQ4A 2BG9E 2W8FA 5KE4A 5HEOA 4Z91A 4HFCA 3ZDGA 4A97A 5LG3A 2PGZA 4ZJSA 4ZJTA 5AFKA 2WNLA 2WNCA 2XQ9A 5J5GA 3UUBA 4Z90A 5KZUA 2C9TA 2BYRA 2YOEA 3P50A 4LMJA 4XK9A 2XNTA 3RQWA 4DBMA 5J5FA 1I9BA 4UXUA 3EI0A 2BR7A 1UV6A 3WTNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5AFN A;  2YMD A;  2VL0 A;  2Y54 A;  2BG9 A;  5L4H A;  3U8L A;  2W8G A;  4QH1 A;  5AFJ A;  4LML A;  2Y7Y A;  3ZDH A;  3ZKR A;  2ZJU A;  3SH1 A;  3EHZ A;  2XQA A;  2BYP A;  5AFL A;  5HEG A;  4ALX A;  5HEU A;  2Y57 A;  2WNJ A;  3PMZ A;  3RIF A;  4WV9 A;  3WTH A;  4QH4 A;  5J0Z A;  3RQU A;  4ILC A;  2BG9 B;  4QAA A;  3JAE A;  3SQ9 A;  4X5T A;  4ILB A;  3RIA A;  2UZ6 A;  3TLW A;  4ZR6 A;  5FJV A;  4TNV A;  5BP0 A;  5J5H A;  3LSV A;  2XYS A;  3JAF A;  4HFI A;  4LMK A;  5HCM A;  4ZZB A;  5JME A;  2X00 A;  3U8J A;  2Y58 A;  2Y56 A;  4HFE A;  4IRE A;  2BG9 C;  4TWF A;  4UM3 A;  4UY2 A;  5L4E A;  2YKS A;  3WTM A;  1UW6 A;  3SIO A;  3EAM A;  3UU6 A;  4UM3 S;  5J5I A;  2QC1 B;  2XNV A;  5BRX A;  2XQ6 A;  2WN9 A;  5CFB A;  2XQ3 A;  2XQ5 A;  3IGQ A;  3SQ6 A;  1UX2 A;  3UU4 A;  5TVC A;  4A98 A;  4FRR A;  3WTJ A;  3C84 A;  4BQT A;  4NPP A;  3JAD A;  2PH9 A;  2XQ7 A;  2BYN A;  3RHW A;  2XZ5 A;  5L47 A;  4IL9 A;  4ZRU A;  3TLS A;  2BR8 A;  3WTO A;  5HEH A;  3TLT A;  4HFH A;  4TWH A;  2XYT A;  3UU3 A;  3RI5 A;  2BYS A;  4IL4 A;  3UU8 A;  5IUX A;  4F8H A;  2XZ6 A;  3C79 A;  4HFB A;  3WTL A;  4BFQ A;  4EZ1 A;  3UU5 A;  5SYO A;  5AFH A;  2XQ8 A;  4HFD A;  4UM1 A;  2X00 D;  2ZJV A;  4QAC A;  4PIR A;  5AFM A;  3GUA A;  4TWD A;  5LXB A;  3UQ7 A;  4QAB A;  2BYQ A;  4ILA A;  4TNW A;  5AIN A;  4ZK4 A;  4NZB A;  2BJ0 A;  4AFG A;  4AFT A;  2YN6 A;  4ZZC A;  4UM3 P;  5CO5 A;  3U8N A;  3WIP A;  3TLV A;  3U8K A;  4XHE A;  4ZK1 A;  4COF A;  2YME A;  3T4M A;  3WTI A;  2XNU A;  3WTK A;  4HQP A;  5HCJ A;  2WZY A;  5BW2 A;  3PEO A;  3UQ4 A;  4AFH A;  3U8M A;  5HEJ A;  4QH5 A;  4B5D A;  5AFM B;  3TLU A;  3P4W A;  4D01 A;  2XQ4 A;  2BG9 E;  2W8F A;  5KE4 A;  5HEO A;  4Z91 A;  4HFC A;  3ZDG A;  4A97 A;  5LG3 A;  2PGZ A;  4ZJS A;  4ZJT A;  5AFK A;  2WNL A;  2WNC A;  2XQ9 A;  5J5G A;  3UUB A;  4Z90 A;  5KZU A;  2C9T A;  2BYR A;  2YOE A;  3P50 A;  4LMJ A;  4XK9 A;  2XNT A;  3RQW A;  4DBM A;  5J5F A;  1I9B A;  4UXU A;  3EI0 A;  2BR7 A;  1UV6 A;  3WTN A; 
#chains in the Genus database with same CATH topology
 5AFN A;  2YMD A;  2VL0 A;  2Y54 A;  2BG9 A;  5L4H A;  3U8L A;  2W8G A;  4QH1 A;  5AFJ A;  4LML A;  2Y7Y A;  3ZDH A;  3ZKR A;  2ZJU A;  3SH1 A;  3EHZ A;  2XQA A;  2BYP A;  5AFL A;  5HEG A;  4ALX A;  5HEU A;  2Y57 A;  2WNJ A;  3PMZ A;  3RIF A;  4WV9 A;  3WTH A;  4QH4 A;  5J0Z A;  3RQU A;  4ILC A;  2BG9 B;  4QAA A;  3JAE A;  3SQ9 A;  4X5T A;  4ILB A;  3RIA A;  2UZ6 A;  3TLW A;  4ZR6 A;  5FJV A;  4TNV A;  5BP0 A;  5J5H A;  3LSV A;  2XYS A;  3JAF A;  4HFI A;  4LMK A;  5HCM A;  4ZZB A;  5JME A;  2X00 A;  3U8J A;  2Y58 A;  2Y56 A;  4HFE A;  4IRE A;  2BG9 C;  4TWF A;  4UM3 A;  4UY2 A;  5L4E A;  2YKS A;  3WTM A;  1UW6 A;  3SIO A;  3EAM A;  3UU6 A;  4UM3 S;  5J5I A;  2QC1 B;  2XNV A;  5BRX A;  2XQ6 A;  2WN9 A;  5CFB A;  2XQ3 A;  2XQ5 A;  3IGQ A;  3SQ6 A;  1UX2 A;  3UU4 A;  5TVC A;  4A98 A;  4FRR A;  3WTJ A;  3C84 A;  4BQT A;  4NPP A;  3JAD A;  2PH9 A;  2XQ7 A;  2BYN A;  3RHW A;  2XZ5 A;  5L47 A;  4IL9 A;  4ZRU A;  3TLS A;  2BR8 A;  3WTO A;  5HEH A;  3TLT A;  4HFH A;  4TWH A;  2XYT A;  3UU3 A;  3RI5 A;  2BYS A;  4IL4 A;  3UU8 A;  5IUX A;  4F8H A;  2XZ6 A;  3C79 A;  4HFB A;  3WTL A;  4BFQ A;  4EZ1 A;  3UU5 A;  5SYO A;  5AFH A;  2XQ8 A;  4HFD A;  4UM1 A;  2X00 D;  2ZJV A;  4QAC A;  4PIR A;  5AFM A;  3GUA A;  4TWD A;  5LXB A;  3UQ7 A;  4QAB A;  2BYQ A;  4ILA A;  4TNW A;  5AIN A;  4ZK4 A;  4NZB A;  2BJ0 A;  4AFG A;  4AFT A;  2YN6 A;  4ZZC A;  4UM3 P;  5CO5 A;  3U8N A;  3WIP A;  3TLV A;  3U8K A;  4XHE A;  4ZK1 A;  4COF A;  2YME A;  3T4M A;  3WTI A;  2XNU A;  3WTK A;  4HQP A;  5HCJ A;  2WZY A;  5BW2 A;  3PEO A;  3UQ4 A;  4AFH A;  3U8M A;  5HEJ A;  4QH5 A;  4B5D A;  5AFM B;  3TLU A;  3P4W A;  4D01 A;  2XQ4 A;  2BG9 E;  2W8F A;  5KE4 A;  5HEO A;  4Z91 A;  4HFC A;  3ZDG A;  4A97 A;  5LG3 A;  2PGZ A;  4ZJS A;  4ZJT A;  5AFK A;  2WNL A;  2WNC A;  2XQ9 A;  5J5G A;  3UUB A;  4Z90 A;  5KZU A;  2C9T A;  2BYR A;  2YOE A;  3P50 A;  4LMJ A;  4XK9 A;  2XNT A;  3RQW A;  4DBM A;  5J5F A;  1I9B A;  4UXU A;  3EI0 A;  2BR7 A;  1UV6 A;  3WTN A; 
#chains in the Genus database with same CATH homology
 5AFN A;  2YMD A;  2VL0 A;  2Y54 A;  2BG9 A;  5L4H A;  3U8L A;  2W8G A;  4QH1 A;  5AFJ A;  4LML A;  2Y7Y A;  3ZDH A;  3ZKR A;  2ZJU A;  3SH1 A;  3EHZ A;  2XQA A;  2BYP A;  5AFL A;  5HEG A;  4ALX A;  5HEU A;  2Y57 A;  2WNJ A;  3PMZ A;  3RIF A;  4WV9 A;  3WTH A;  4QH4 A;  5J0Z A;  3RQU A;  4ILC A;  2BG9 B;  4QAA A;  3JAE A;  3SQ9 A;  4X5T A;  4ILB A;  3RIA A;  2UZ6 A;  3TLW A;  4ZR6 A;  5FJV A;  4TNV A;  5BP0 A;  5J5H A;  3LSV A;  2XYS A;  3JAF A;  4HFI A;  4LMK A;  5HCM A;  4ZZB A;  5JME A;  2X00 A;  3U8J A;  2Y58 A;  2Y56 A;  4HFE A;  4IRE A;  2BG9 C;  4TWF A;  4UM3 A;  4UY2 A;  5L4E A;  2YKS A;  3WTM A;  1UW6 A;  3SIO A;  3EAM A;  3UU6 A;  4UM3 S;  5J5I A;  2QC1 B;  2XNV A;  5BRX A;  2XQ6 A;  2WN9 A;  5CFB A;  2XQ3 A;  2XQ5 A;  3IGQ A;  3SQ6 A;  1UX2 A;  3UU4 A;  5TVC A;  4A98 A;  4FRR A;  3WTJ A;  3C84 A;  4BQT A;  4NPP A;  3JAD A;  2PH9 A;  2XQ7 A;  2BYN A;  3RHW A;  2XZ5 A;  5L47 A;  4IL9 A;  4ZRU A;  3TLS A;  2BR8 A;  3WTO A;  5HEH A;  3TLT A;  4HFH A;  4TWH A;  2XYT A;  3UU3 A;  3RI5 A;  2BYS A;  4IL4 A;  3UU8 A;  5IUX A;  4F8H A;  2XZ6 A;  3C79 A;  4HFB A;  3WTL A;  4BFQ A;  4EZ1 A;  3UU5 A;  5SYO A;  5AFH A;  2XQ8 A;  4HFD A;  4UM1 A;  2X00 D;  2ZJV A;  4QAC A;  4PIR A;  5AFM A;  3GUA A;  4TWD A;  5LXB A;  3UQ7 A;  4QAB A;  2BYQ A;  4ILA A;  4TNW A;  5AIN A;  4ZK4 A;  4NZB A;  2BJ0 A;  4AFG A;  4AFT A;  2YN6 A;  4ZZC A;  4UM3 P;  5CO5 A;  3U8N A;  3WIP A;  3TLV A;  3U8K A;  4XHE A;  4ZK1 A;  4COF A;  2YME A;  3T4M A;  3WTI A;  2XNU A;  3WTK A;  4HQP A;  5HCJ A;  2WZY A;  5BW2 A;  3PEO A;  3UQ4 A;  4AFH A;  3U8M A;  5HEJ A;  4QH5 A;  4B5D A;  5AFM B;  3TLU A;  3P4W A;  4D01 A;  2XQ4 A;  2BG9 E;  2W8F A;  5KE4 A;  5HEO A;  4Z91 A;  4HFC A;  3ZDG A;  4A97 A;  5LG3 A;  2PGZ A;  4ZJS A;  4ZJT A;  5AFK A;  2WNL A;  2WNC A;  2XQ9 A;  5J5G A;  3UUB A;  4Z90 A;  5KZU A;  2C9T A;  2BYR A;  2YOE A;  3P50 A;  4LMJ A;  4XK9 A;  2XNT A;  3RQW A;  4DBM A;  5J5F A;  1I9B A;  4UXU A;  3EI0 A;  2BR7 A;  1UV6 A;  3WTN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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