2BYQA

Crystal structure of aplysia californica achbp in complex with epibatidine
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
214
structure length
214
Chain Sequence
DDDDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Aplysia Achbp Complexes with Nicotinic Agonists and Antagonists Reveal Distinctive Binding Interfaces and Conformations.
pubmed doi rcsb
molecule tags Receptor
source organism Aplysia californica
molecule keywords SOLUBLE ACETYLCHOLINE RECEPTOR
total genus 51
structure length 214
sequence length 214
chains with identical sequence B, C, D, E
ec nomenclature
pdb deposition date 2005-08-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 2byqA00
5JMEA 4AFHA 3UQ4A 4HFBA 3UU6A 1I9BA 4PIRA 4WV9A 2C9TA 2XQ5A 3WTIA 4BFQA 4ZK4A 3U8JA 3SQ9A 4TWHA 2Y57A 3P4WA 5LG3A 2YN6A 4UY2A 4Z91A 4QH1A 4UM3A 4XK9A 5FJVA 5KE4A 4LMKA 2WN9A 3UUBA 3WTJA 5HEJA 3UU8A 2PH9A 3RHWA 2BG9E 3ZDHA 3T4MA 4LMJA 5SYOA 4ILCA 5IUXA 4COFA 2WNLA 3RQUA 2WNCA 4IL9A 3RIAA 4TNVA 4ALXA 2XYTA 3WTMA 3EI0A 2BG9C 3U8MA 3JAEA 2YOEA 5AFNA 2BG9A 3TLWA 2BYNA 2BYQA 3IGQA 2XQAA 4UM1A 4ZRUA 4TWFA 5J5FA 5L47A 3WTLA 5AFMB 4AFTA 2XNVA 2Y56A 5HCMA 4ZJTA 3RI5A 4DBMA 2YMDA 4BQTA 2XQ8A 4ZZCA 5KZUA 3C79A 2W8GA 2Y7YA 3C84A 4X5TA 4IL4A 4TNWA 4XHEA 5J5HA 3RIFA 5BRXA 4ZJSA 2BG9B 2YKSA 4FRRA 5BP0A 5HEOA 4ILAA 3U8LA 4Z90A 5AFMA 2XZ5A 4D01A 2WZYA 4QH4A 3JADA 5L4EA 3SH1A 4HFEA 2Y58A 5AFLA 2BR7A 4NPPA 2ZJVA 2W8FA 1UV6A 3LSVA 3UU5A 2ZJUA 3PMZA 4QACA 3SIOA 3WTHA 4A98A 2XQ7A 3WTOA 5LXBA 2QC1B 2YMEA 3TLVA 2UZ6A 2BYSA 3UU4A 4UXUA 4HFCA 2BR8A 4ZZBA 2XZ6A 4QABA 3TLTA 5AINA 3WTNA 1UX2A 2WNJA 5HEGA 3SQ6A 3JAFA 5HCJA 1UW6A 5HEHA 2BYRA 3TLSA 3U8NA 4A97A 3EAMA 3WIPA 5AFHA 5AFKA 4UM3P 3UQ7A 2XQ3A 2BYPA 3P50A 4HFHA 4HFDA 4HQPA 3WTKA 2XQ6A 2VL0A 4ILBA 4HFIA 4IREA 5HEUA 3ZKRA 2XNTA 4AFGA 5CFBA 4EZ1A 3UU3A 5AFJA 5L4HA 4ZR6A 5TVCA 4B5DA 3EHZA 3ZDGA 4QAAA 2BJ0A 3TLUA 5J5IA 5J0ZA 2XQ4A 3PEOA 2Y54A 2X00A 4UM3S 2PGZA 4ZK1A 2XYSA 4QH5A 3RQWA 5BW2A 4F8HA 4LMLA 2X00D 2XQ9A 3U8KA 2XNUA 3GUAA 5CO5A 4NZBA 5J5GA 4TWDA
chains in the Genus database with same CATH superfamily
5JMEA 4AFHA 3UQ4A 4HFBA 3UU6A 1I9BA 4PIRA 4WV9A 2C9TA 2XQ5A 3WTIA 4BFQA 4ZK4A 3U8JA 3SQ9A 4TWHA 2Y57A 3P4WA 5LG3A 2YN6A 4UY2A 4Z91A 4QH1A 4UM3A 4XK9A 5FJVA 5KE4A 4LMKA 2WN9A 3UUBA 3WTJA 5HEJA 3UU8A 2PH9A 3RHWA 2BG9E 3ZDHA 3T4MA 4LMJA 5SYOA 4ILCA 5IUXA 4COFA 2WNLA 3RQUA 2WNCA 4IL9A 3RIAA 4TNVA 4ALXA 2XYTA 3WTMA 3EI0A 2BG9C 3U8MA 3JAEA 2YOEA 5AFNA 2BG9A 3TLWA 2BYNA 2BYQA 3IGQA 2XQAA 4UM1A 4ZRUA 4TWFA 5J5FA 5L47A 3WTLA 5AFMB 4AFTA 2XNVA 2Y56A 5HCMA 4ZJTA 3RI5A 4DBMA 2YMDA 4BQTA 2XQ8A 4ZZCA 5KZUA 3C79A 2W8GA 2Y7YA 3C84A 4X5TA 4IL4A 4TNWA 4XHEA 5J5HA 3RIFA 5BRXA 4ZJSA 2BG9B 2YKSA 4FRRA 5BP0A 5HEOA 4ILAA 3U8LA 4Z90A 5AFMA 2XZ5A 4D01A 2WZYA 4QH4A 3JADA 5L4EA 3SH1A 4HFEA 2Y58A 5AFLA 2BR7A 4NPPA 2ZJVA 2W8FA 1UV6A 3LSVA 3UU5A 2ZJUA 3PMZA 4QACA 3SIOA 3WTHA 4A98A 2XQ7A 3WTOA 5LXBA 2QC1B 2YMEA 3TLVA 2UZ6A 2BYSA 3UU4A 4UXUA 4HFCA 2BR8A 4ZZBA 2XZ6A 4QABA 3TLTA 5AINA 3WTNA 1UX2A 2WNJA 5HEGA 3SQ6A 3JAFA 5HCJA 1UW6A 5HEHA 2BYRA 3TLSA 3U8NA 4A97A 3EAMA 3WIPA 5AFHA 5AFKA 4UM3P 3UQ7A 2XQ3A 2BYPA 3P50A 4HFHA 4HFDA 4HQPA 3WTKA 2XQ6A 2VL0A 4ILBA 4HFIA 4IREA 5HEUA 3ZKRA 2XNTA 4AFGA 5CFBA 4EZ1A 3UU3A 5AFJA 5L4HA 4ZR6A 5TVCA 4B5DA 3EHZA 3ZDGA 4QAAA 2BJ0A 3TLUA 5J5IA 5J0ZA 2XQ4A 3PEOA 2Y54A 2X00A 4UM3S 2PGZA 4ZK1A 2XYSA 4QH5A 3RQWA 5BW2A 4F8HA 4LMLA 2X00D 2XQ9A 3U8KA 2XNUA 3GUAA 5CO5A 4NZBA 5J5GA 4TWDA
chains in the Genus database with same CATH topology
5JMEA 4AFHA 3UQ4A 4HFBA 3UU6A 1I9BA 4PIRA 4WV9A 2C9TA 2XQ5A 3WTIA 4BFQA 4ZK4A 3U8JA 3SQ9A 4TWHA 2Y57A 3P4WA 5LG3A 2YN6A 4UY2A 4Z91A 4QH1A 4UM3A 4XK9A 5FJVA 5KE4A 4LMKA 2WN9A 3UUBA 3WTJA 5HEJA 3UU8A 2PH9A 3RHWA 2BG9E 3ZDHA 3T4MA 4LMJA 5SYOA 4ILCA 5IUXA 4COFA 2WNLA 3RQUA 2WNCA 4IL9A 3RIAA 4TNVA 4ALXA 2XYTA 3WTMA 3EI0A 2BG9C 3U8MA 3JAEA 2YOEA 5AFNA 2BG9A 3TLWA 2BYNA 2BYQA 3IGQA 2XQAA 4UM1A 4ZRUA 4TWFA 5J5FA 5L47A 3WTLA 5AFMB 4AFTA 2XNVA 2Y56A 5HCMA 4ZJTA 3RI5A 4DBMA 2YMDA 4BQTA 2XQ8A 4ZZCA 5KZUA 3C79A 2W8GA 2Y7YA 3C84A 4X5TA 4IL4A 4TNWA 4XHEA 5J5HA 3RIFA 5BRXA 4ZJSA 2BG9B 2YKSA 4FRRA 5BP0A 5HEOA 4ILAA 3U8LA 4Z90A 5AFMA 2XZ5A 4D01A 2WZYA 4QH4A 3JADA 5L4EA 3SH1A 4HFEA 2Y58A 5AFLA 2BR7A 4NPPA 2ZJVA 2W8FA 1UV6A 3LSVA 3UU5A 2ZJUA 3PMZA 4QACA 3SIOA 3WTHA 4A98A 2XQ7A 3WTOA 5LXBA 2QC1B 2YMEA 3TLVA 2UZ6A 2BYSA 3UU4A 4UXUA 4HFCA 2BR8A 4ZZBA 2XZ6A 4QABA 3TLTA 5AINA 3WTNA 1UX2A 2WNJA 5HEGA 3SQ6A 3JAFA 5HCJA 1UW6A 5HEHA 2BYRA 3TLSA 3U8NA 4A97A 3EAMA 3WIPA 5AFHA 5AFKA 4UM3P 3UQ7A 2XQ3A 2BYPA 3P50A 4HFHA 4HFDA 4HQPA 3WTKA 2XQ6A 2VL0A 4ILBA 4HFIA 4IREA 5HEUA 3ZKRA 2XNTA 4AFGA 5CFBA 4EZ1A 3UU3A 5AFJA 5L4HA 4ZR6A 5TVCA 4B5DA 3EHZA 3ZDGA 4QAAA 2BJ0A 3TLUA 5J5IA 5J0ZA 2XQ4A 3PEOA 2Y54A 2X00A 4UM3S 2PGZA 4ZK1A 2XYSA 4QH5A 3RQWA 5BW2A 4F8HA 4LMLA 2X00D 2XQ9A 3U8KA 2XNUA 3GUAA 5CO5A 4NZBA 5J5GA 4TWDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5JME A;  4AFH A;  3UQ4 A;  4HFB A;  3UU6 A;  1I9B A;  4PIR A;  4WV9 A;  2C9T A;  2XQ5 A;  3WTI A;  4BFQ A;  4ZK4 A;  3U8J A;  3SQ9 A;  4TWH A;  2Y57 A;  3P4W A;  5LG3 A;  2YN6 A;  4UY2 A;  4Z91 A;  4QH1 A;  4UM3 A;  4XK9 A;  5FJV A;  5KE4 A;  4LMK A;  2WN9 A;  3UUB A;  3WTJ A;  5HEJ A;  3UU8 A;  2PH9 A;  3RHW A;  2BG9 E;  3ZDH A;  3T4M A;  4LMJ A;  5SYO A;  4ILC A;  5IUX A;  4COF A;  2WNL A;  3RQU A;  2WNC A;  4IL9 A;  3RIA A;  4TNV A;  4ALX A;  2XYT A;  3WTM A;  3EI0 A;  2BG9 C;  3U8M A;  3JAE A;  2YOE A;  5AFN A;  2BG9 A;  3TLW A;  2BYN A;  2BYQ A;  3IGQ A;  2XQA A;  4UM1 A;  4ZRU A;  4TWF A;  5J5F A;  5L47 A;  3WTL A;  5AFM B;  4AFT A;  2XNV A;  2Y56 A;  5HCM A;  4ZJT A;  3RI5 A;  4DBM A;  2YMD A;  4BQT A;  2XQ8 A;  4ZZC A;  5KZU A;  3C79 A;  2W8G A;  2Y7Y A;  3C84 A;  4X5T A;  4IL4 A;  4TNW A;  4XHE A;  5J5H A;  3RIF A;  5BRX A;  4ZJS A;  2BG9 B;  2YKS A;  4FRR A;  5BP0 A;  5HEO A;  4ILA A;  3U8L A;  4Z90 A;  5AFM A;  2XZ5 A;  4D01 A;  2WZY A;  4QH4 A;  3JAD A;  5L4E A;  3SH1 A;  4HFE A;  2Y58 A;  5AFL A;  2BR7 A;  4NPP A;  2ZJV A;  2W8F A;  1UV6 A;  3LSV A;  3UU5 A;  2ZJU A;  3PMZ A;  4QAC A;  3SIO A;  3WTH A;  4A98 A;  2XQ7 A;  3WTO A;  5LXB A;  2QC1 B;  2YME A;  3TLV A;  2UZ6 A;  2BYS A;  3UU4 A;  4UXU A;  4HFC A;  2BR8 A;  4ZZB A;  2XZ6 A;  4QAB A;  3TLT A;  5AIN A;  3WTN A;  1UX2 A;  2WNJ A;  5HEG A;  3SQ6 A;  3JAF A;  5HCJ A;  1UW6 A;  5HEH A;  2BYR A;  3TLS A;  3U8N A;  4A97 A;  3EAM A;  3WIP A;  5AFH A;  5AFK A;  4UM3 P;  3UQ7 A;  2XQ3 A;  2BYP A;  3P50 A;  4HFH A;  4HFD A;  4HQP A;  3WTK A;  2XQ6 A;  2VL0 A;  4ILB A;  4HFI A;  4IRE A;  5HEU A;  3ZKR A;  2XNT A;  4AFG A;  5CFB A;  4EZ1 A;  3UU3 A;  5AFJ A;  5L4H A;  4ZR6 A;  5TVC A;  4B5D A;  3EHZ A;  3ZDG A;  4QAA A;  2BJ0 A;  3TLU A;  5J5I A;  5J0Z A;  2XQ4 A;  3PEO A;  2Y54 A;  2X00 A;  4UM3 S;  2PGZ A;  4ZK1 A;  2XYS A;  4QH5 A;  3RQW A;  5BW2 A;  4F8H A;  4LML A;  2X00 D;  2XQ9 A;  3U8K A;  2XNU A;  3GUA A;  5CO5 A;  4NZB A;  5J5G A;  4TWD A; 
#chains in the Genus database with same CATH topology
 5JME A;  4AFH A;  3UQ4 A;  4HFB A;  3UU6 A;  1I9B A;  4PIR A;  4WV9 A;  2C9T A;  2XQ5 A;  3WTI A;  4BFQ A;  4ZK4 A;  3U8J A;  3SQ9 A;  4TWH A;  2Y57 A;  3P4W A;  5LG3 A;  2YN6 A;  4UY2 A;  4Z91 A;  4QH1 A;  4UM3 A;  4XK9 A;  5FJV A;  5KE4 A;  4LMK A;  2WN9 A;  3UUB A;  3WTJ A;  5HEJ A;  3UU8 A;  2PH9 A;  3RHW A;  2BG9 E;  3ZDH A;  3T4M A;  4LMJ A;  5SYO A;  4ILC A;  5IUX A;  4COF A;  2WNL A;  3RQU A;  2WNC A;  4IL9 A;  3RIA A;  4TNV A;  4ALX A;  2XYT A;  3WTM A;  3EI0 A;  2BG9 C;  3U8M A;  3JAE A;  2YOE A;  5AFN A;  2BG9 A;  3TLW A;  2BYN A;  2BYQ A;  3IGQ A;  2XQA A;  4UM1 A;  4ZRU A;  4TWF A;  5J5F A;  5L47 A;  3WTL A;  5AFM B;  4AFT A;  2XNV A;  2Y56 A;  5HCM A;  4ZJT A;  3RI5 A;  4DBM A;  2YMD A;  4BQT A;  2XQ8 A;  4ZZC A;  5KZU A;  3C79 A;  2W8G A;  2Y7Y A;  3C84 A;  4X5T A;  4IL4 A;  4TNW A;  4XHE A;  5J5H A;  3RIF A;  5BRX A;  4ZJS A;  2BG9 B;  2YKS A;  4FRR A;  5BP0 A;  5HEO A;  4ILA A;  3U8L A;  4Z90 A;  5AFM A;  2XZ5 A;  4D01 A;  2WZY A;  4QH4 A;  3JAD A;  5L4E A;  3SH1 A;  4HFE A;  2Y58 A;  5AFL A;  2BR7 A;  4NPP A;  2ZJV A;  2W8F A;  1UV6 A;  3LSV A;  3UU5 A;  2ZJU A;  3PMZ A;  4QAC A;  3SIO A;  3WTH A;  4A98 A;  2XQ7 A;  3WTO A;  5LXB A;  2QC1 B;  2YME A;  3TLV A;  2UZ6 A;  2BYS A;  3UU4 A;  4UXU A;  4HFC A;  2BR8 A;  4ZZB A;  2XZ6 A;  4QAB A;  3TLT A;  5AIN A;  3WTN A;  1UX2 A;  2WNJ A;  5HEG A;  3SQ6 A;  3JAF A;  5HCJ A;  1UW6 A;  5HEH A;  2BYR A;  3TLS A;  3U8N A;  4A97 A;  3EAM A;  3WIP A;  5AFH A;  5AFK A;  4UM3 P;  3UQ7 A;  2XQ3 A;  2BYP A;  3P50 A;  4HFH A;  4HFD A;  4HQP A;  3WTK A;  2XQ6 A;  2VL0 A;  4ILB A;  4HFI A;  4IRE A;  5HEU A;  3ZKR A;  2XNT A;  4AFG A;  5CFB A;  4EZ1 A;  3UU3 A;  5AFJ A;  5L4H A;  4ZR6 A;  5TVC A;  4B5D A;  3EHZ A;  3ZDG A;  4QAA A;  2BJ0 A;  3TLU A;  5J5I A;  5J0Z A;  2XQ4 A;  3PEO A;  2Y54 A;  2X00 A;  4UM3 S;  2PGZ A;  4ZK1 A;  2XYS A;  4QH5 A;  3RQW A;  5BW2 A;  4F8H A;  4LML A;  2X00 D;  2XQ9 A;  3U8K A;  2XNU A;  3GUA A;  5CO5 A;  4NZB A;  5J5G A;  4TWD A; 
#chains in the Genus database with same CATH homology
 5JME A;  4AFH A;  3UQ4 A;  4HFB A;  3UU6 A;  1I9B A;  4PIR A;  4WV9 A;  2C9T A;  2XQ5 A;  3WTI A;  4BFQ A;  4ZK4 A;  3U8J A;  3SQ9 A;  4TWH A;  2Y57 A;  3P4W A;  5LG3 A;  2YN6 A;  4UY2 A;  4Z91 A;  4QH1 A;  4UM3 A;  4XK9 A;  5FJV A;  5KE4 A;  4LMK A;  2WN9 A;  3UUB A;  3WTJ A;  5HEJ A;  3UU8 A;  2PH9 A;  3RHW A;  2BG9 E;  3ZDH A;  3T4M A;  4LMJ A;  5SYO A;  4ILC A;  5IUX A;  4COF A;  2WNL A;  3RQU A;  2WNC A;  4IL9 A;  3RIA A;  4TNV A;  4ALX A;  2XYT A;  3WTM A;  3EI0 A;  2BG9 C;  3U8M A;  3JAE A;  2YOE A;  5AFN A;  2BG9 A;  3TLW A;  2BYN A;  2BYQ A;  3IGQ A;  2XQA A;  4UM1 A;  4ZRU A;  4TWF A;  5J5F A;  5L47 A;  3WTL A;  5AFM B;  4AFT A;  2XNV A;  2Y56 A;  5HCM A;  4ZJT A;  3RI5 A;  4DBM A;  2YMD A;  4BQT A;  2XQ8 A;  4ZZC A;  5KZU A;  3C79 A;  2W8G A;  2Y7Y A;  3C84 A;  4X5T A;  4IL4 A;  4TNW A;  4XHE A;  5J5H A;  3RIF A;  5BRX A;  4ZJS A;  2BG9 B;  2YKS A;  4FRR A;  5BP0 A;  5HEO A;  4ILA A;  3U8L A;  4Z90 A;  5AFM A;  2XZ5 A;  4D01 A;  2WZY A;  4QH4 A;  3JAD A;  5L4E A;  3SH1 A;  4HFE A;  2Y58 A;  5AFL A;  2BR7 A;  4NPP A;  2ZJV A;  2W8F A;  1UV6 A;  3LSV A;  3UU5 A;  2ZJU A;  3PMZ A;  4QAC A;  3SIO A;  3WTH A;  4A98 A;  2XQ7 A;  3WTO A;  5LXB A;  2QC1 B;  2YME A;  3TLV A;  2UZ6 A;  2BYS A;  3UU4 A;  4UXU A;  4HFC A;  2BR8 A;  4ZZB A;  2XZ6 A;  4QAB A;  3TLT A;  5AIN A;  3WTN A;  1UX2 A;  2WNJ A;  5HEG A;  3SQ6 A;  3JAF A;  5HCJ A;  1UW6 A;  5HEH A;  2BYR A;  3TLS A;  3U8N A;  4A97 A;  3EAM A;  3WIP A;  5AFH A;  5AFK A;  4UM3 P;  3UQ7 A;  2XQ3 A;  2BYP A;  3P50 A;  4HFH A;  4HFD A;  4HQP A;  3WTK A;  2XQ6 A;  2VL0 A;  4ILB A;  4HFI A;  4IRE A;  5HEU A;  3ZKR A;  2XNT A;  4AFG A;  5CFB A;  4EZ1 A;  3UU3 A;  5AFJ A;  5L4H A;  4ZR6 A;  5TVC A;  4B5D A;  3EHZ A;  3ZDG A;  4QAA A;  2BJ0 A;  3TLU A;  5J5I A;  5J0Z A;  2XQ4 A;  3PEO A;  2Y54 A;  2X00 A;  4UM3 S;  2PGZ A;  4ZK1 A;  2XYS A;  4QH5 A;  3RQW A;  5BW2 A;  4F8H A;  4LML A;  2X00 D;  2XQ9 A;  3U8K A;  2XNU A;  3GUA A;  5CO5 A;  4NZB A;  5J5G A;  4TWD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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