2WN9A

Crystal structure of aplysia achbp in complex with 4-0h-dmxba
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
209
structure length
209
Chain Sequence
LHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal alpha7 nicotinic acetylcholine receptor.
pubmed doi rcsb
molecule tags Receptor
source organism Aplysia californica
molecule keywords SOLUBLE ACETYLCHOLINE RECEPTOR
total genus 50
structure length 209
sequence length 209
chains with identical sequence B, C, D, E
ec nomenclature
pdb deposition date 2009-07-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 2wn9A00
5HCJA 2ZJVA 5HCMA 2BYSA 2WZYA 3RIFA 3GUAA 5BRXA 4F8HA 4A98A 2Y57A 3UQ7A 3SH1A 3EHZA 4QH4A 3UU6A 5IUXA 5J5HA 2XQAA 4TWDA 2XZ5A 2PGZA 3RI5A 5KE4A 4IREA 4WV9A 2YN6A 3U8LA 4AFHA 4EZ1A 5CO5A 3UUBA 5AFHA 5J5IA 2W8FA 2BG9E 2BYRA 4NZBA 5HEGA 2XYTA 5AFNA 3EI0A 4QABA 4ILBA 1UW6A 1UX2A 2Y7YA 4QACA 3ZDHA 2UZ6A 2WNLA 2XNTA 4NPPA 5BP0A 5CFBA 4UM1A 5FJVA 2XQ3A 4ZR6A 2BYNA 5L4EA 4UM3A 3WTOA 4XK9A 4ZJSA 3TLVA 2BR8A 4TWHA 2XQ4A 3U8MA 3UQ4A 3UU5A 3RQWA 3EAMA 2BJ0A 4HFHA 5HEUA 3RIAA 2BG9B 3TLWA 5AFMA 4HQPA 2VL0A 4DBMA 4PIRA 5SYOA 5LXBA 2XNVA 3WTHA 3JAEA 4TNVA 4UM3S 4LMLA 4Z90A 4AFTA 2WN9A 4IL9A 2Y58A 2Y56A 5L4HA 3RQUA 3SIOA 3ZDGA 5J5FA 5J5GA 4ZK1A 3JADA 2PH9A 4ILAA 4FRRA 4TNWA 4ALXA 4ZZBA 5J0ZA 3PEOA 2X00A 3UU4A 5L47A 2Y54A 3T4MA 5AFJA 2W8GA 2BYPA 4HFIA 4XHEA 4HFDA 4ZJTA 3TLSA 2XQ8A 2XQ7A 2YMEA 2WNCA 2BYQA 2C9TA 4UXUA 4QH1A 3WTLA 1UV6A 3UU3A 5AFMB 3U8NA 5BW2A 3C84A 1I9BA 3WTKA 2X00D 4X5TA 4HFEA 2XQ9A 3PMZA 4AFGA 3P50A 3UU8A 4BFQA 2YKSA 3P4WA 4HFBA 4LMKA 2XNUA 3TLUA 4COFA 4ZZCA 2XZ6A 5AFKA 3WIPA 3U8KA 3U8JA 2QC1B 3WTMA 4B5DA 5HEJA 5JMEA 3C79A 4QH5A 4TWFA 4ILCA 5HEHA 4ZK4A 4ZRUA 2BG9A 3WTJA 2XQ5A 4Z91A 3RHWA 5HEOA 4UM3P 5AINA 3SQ6A 4HFCA 4D01A 2ZJUA 2XYSA 4BQTA 5KZUA 4IL4A 2BG9C 5LG3A 3WTIA 2YMDA 4QAAA 2WNJA 3IGQA 4UY2A 2YOEA 3ZKRA 4A97A 5TVCA 3JAFA 5AFLA 2BR7A 3WTNA 3LSVA 3SQ9A 4LMJA 3TLTA 2XQ6A
chains in the Genus database with same CATH superfamily
5HCJA 2ZJVA 5HCMA 2BYSA 2WZYA 3RIFA 3GUAA 5BRXA 4F8HA 4A98A 2Y57A 3UQ7A 3SH1A 3EHZA 4QH4A 3UU6A 5IUXA 5J5HA 2XQAA 4TWDA 2XZ5A 2PGZA 3RI5A 5KE4A 4IREA 4WV9A 2YN6A 3U8LA 4AFHA 4EZ1A 5CO5A 3UUBA 5AFHA 5J5IA 2W8FA 2BG9E 2BYRA 4NZBA 5HEGA 2XYTA 5AFNA 3EI0A 4QABA 4ILBA 1UW6A 1UX2A 2Y7YA 4QACA 3ZDHA 2UZ6A 2WNLA 2XNTA 4NPPA 5BP0A 5CFBA 4UM1A 5FJVA 2XQ3A 4ZR6A 2BYNA 5L4EA 4UM3A 3WTOA 4XK9A 4ZJSA 3TLVA 2BR8A 4TWHA 2XQ4A 3U8MA 3UQ4A 3UU5A 3RQWA 3EAMA 2BJ0A 4HFHA 5HEUA 3RIAA 2BG9B 3TLWA 5AFMA 4HQPA 2VL0A 4DBMA 4PIRA 5SYOA 5LXBA 2XNVA 3WTHA 3JAEA 4TNVA 4UM3S 4LMLA 4Z90A 4AFTA 2WN9A 4IL9A 2Y58A 2Y56A 5L4HA 3RQUA 3SIOA 3ZDGA 5J5FA 5J5GA 4ZK1A 3JADA 2PH9A 4ILAA 4FRRA 4TNWA 4ALXA 4ZZBA 5J0ZA 3PEOA 2X00A 3UU4A 5L47A 2Y54A 3T4MA 5AFJA 2W8GA 2BYPA 4HFIA 4XHEA 4HFDA 4ZJTA 3TLSA 2XQ8A 2XQ7A 2YMEA 2WNCA 2BYQA 2C9TA 4UXUA 4QH1A 3WTLA 1UV6A 3UU3A 5AFMB 3U8NA 5BW2A 3C84A 1I9BA 3WTKA 2X00D 4X5TA 4HFEA 2XQ9A 3PMZA 4AFGA 3P50A 3UU8A 4BFQA 2YKSA 3P4WA 4HFBA 4LMKA 2XNUA 3TLUA 4COFA 4ZZCA 2XZ6A 5AFKA 3WIPA 3U8KA 3U8JA 2QC1B 3WTMA 4B5DA 5HEJA 5JMEA 3C79A 4QH5A 4TWFA 4ILCA 5HEHA 4ZK4A 4ZRUA 2BG9A 3WTJA 2XQ5A 4Z91A 3RHWA 5HEOA 4UM3P 5AINA 3SQ6A 4HFCA 4D01A 2ZJUA 2XYSA 4BQTA 5KZUA 4IL4A 2BG9C 5LG3A 3WTIA 2YMDA 4QAAA 2WNJA 3IGQA 4UY2A 2YOEA 3ZKRA 4A97A 5TVCA 3JAFA 5AFLA 2BR7A 3WTNA 3LSVA 3SQ9A 4LMJA 3TLTA 2XQ6A
chains in the Genus database with same CATH topology
5HCJA 2ZJVA 5HCMA 2BYSA 2WZYA 3RIFA 3GUAA 5BRXA 4F8HA 4A98A 2Y57A 3UQ7A 3SH1A 3EHZA 4QH4A 3UU6A 5IUXA 5J5HA 2XQAA 4TWDA 2XZ5A 2PGZA 3RI5A 5KE4A 4IREA 4WV9A 2YN6A 3U8LA 4AFHA 4EZ1A 5CO5A 3UUBA 5AFHA 5J5IA 2W8FA 2BG9E 2BYRA 4NZBA 5HEGA 2XYTA 5AFNA 3EI0A 4QABA 4ILBA 1UW6A 1UX2A 2Y7YA 4QACA 3ZDHA 2UZ6A 2WNLA 2XNTA 4NPPA 5BP0A 5CFBA 4UM1A 5FJVA 2XQ3A 4ZR6A 2BYNA 5L4EA 4UM3A 3WTOA 4XK9A 4ZJSA 3TLVA 2BR8A 4TWHA 2XQ4A 3U8MA 3UQ4A 3UU5A 3RQWA 3EAMA 2BJ0A 4HFHA 5HEUA 3RIAA 2BG9B 3TLWA 5AFMA 4HQPA 2VL0A 4DBMA 4PIRA 5SYOA 5LXBA 2XNVA 3WTHA 3JAEA 4TNVA 4UM3S 4LMLA 4Z90A 4AFTA 2WN9A 4IL9A 2Y58A 2Y56A 5L4HA 3RQUA 3SIOA 3ZDGA 5J5FA 5J5GA 4ZK1A 3JADA 2PH9A 4ILAA 4FRRA 4TNWA 4ALXA 4ZZBA 5J0ZA 3PEOA 2X00A 3UU4A 5L47A 2Y54A 3T4MA 5AFJA 2W8GA 2BYPA 4HFIA 4XHEA 4HFDA 4ZJTA 3TLSA 2XQ8A 2XQ7A 2YMEA 2WNCA 2BYQA 2C9TA 4UXUA 4QH1A 3WTLA 1UV6A 3UU3A 5AFMB 3U8NA 5BW2A 3C84A 1I9BA 3WTKA 2X00D 4X5TA 4HFEA 2XQ9A 3PMZA 4AFGA 3P50A 3UU8A 4BFQA 2YKSA 3P4WA 4HFBA 4LMKA 2XNUA 3TLUA 4COFA 4ZZCA 2XZ6A 5AFKA 3WIPA 3U8KA 3U8JA 2QC1B 3WTMA 4B5DA 5HEJA 5JMEA 3C79A 4QH5A 4TWFA 4ILCA 5HEHA 4ZK4A 4ZRUA 2BG9A 3WTJA 2XQ5A 4Z91A 3RHWA 5HEOA 4UM3P 5AINA 3SQ6A 4HFCA 4D01A 2ZJUA 2XYSA 4BQTA 5KZUA 4IL4A 2BG9C 5LG3A 3WTIA 2YMDA 4QAAA 2WNJA 3IGQA 4UY2A 2YOEA 3ZKRA 4A97A 5TVCA 3JAFA 5AFLA 2BR7A 3WTNA 3LSVA 3SQ9A 4LMJA 3TLTA 2XQ6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HCJ A;  2ZJV A;  5HCM A;  2BYS A;  2WZY A;  3RIF A;  3GUA A;  5BRX A;  4F8H A;  4A98 A;  2Y57 A;  3UQ7 A;  3SH1 A;  3EHZ A;  4QH4 A;  3UU6 A;  5IUX A;  5J5H A;  2XQA A;  4TWD A;  2XZ5 A;  2PGZ A;  3RI5 A;  5KE4 A;  4IRE A;  4WV9 A;  2YN6 A;  3U8L A;  4AFH A;  4EZ1 A;  5CO5 A;  3UUB A;  5AFH A;  5J5I A;  2W8F A;  2BG9 E;  2BYR A;  4NZB A;  5HEG A;  2XYT A;  5AFN A;  3EI0 A;  4QAB A;  4ILB A;  1UW6 A;  1UX2 A;  2Y7Y A;  4QAC A;  3ZDH A;  2UZ6 A;  2WNL A;  2XNT A;  4NPP A;  5BP0 A;  5CFB A;  4UM1 A;  5FJV A;  2XQ3 A;  4ZR6 A;  2BYN A;  5L4E A;  4UM3 A;  3WTO A;  4XK9 A;  4ZJS A;  3TLV A;  2BR8 A;  4TWH A;  2XQ4 A;  3U8M A;  3UQ4 A;  3UU5 A;  3RQW A;  3EAM A;  2BJ0 A;  4HFH A;  5HEU A;  3RIA A;  2BG9 B;  3TLW A;  5AFM A;  4HQP A;  2VL0 A;  4DBM A;  4PIR A;  5SYO A;  5LXB A;  2XNV A;  3WTH A;  3JAE A;  4TNV A;  4UM3 S;  4LML A;  4Z90 A;  4AFT A;  2WN9 A;  4IL9 A;  2Y58 A;  2Y56 A;  5L4H A;  3RQU A;  3SIO A;  3ZDG A;  5J5F A;  5J5G A;  4ZK1 A;  3JAD A;  2PH9 A;  4ILA A;  4FRR A;  4TNW A;  4ALX A;  4ZZB A;  5J0Z A;  3PEO A;  2X00 A;  3UU4 A;  5L47 A;  2Y54 A;  3T4M A;  5AFJ A;  2W8G A;  2BYP A;  4HFI A;  4XHE A;  4HFD A;  4ZJT A;  3TLS A;  2XQ8 A;  2XQ7 A;  2YME A;  2WNC A;  2BYQ A;  2C9T A;  4UXU A;  4QH1 A;  3WTL A;  1UV6 A;  3UU3 A;  5AFM B;  3U8N A;  5BW2 A;  3C84 A;  1I9B A;  3WTK A;  2X00 D;  4X5T A;  4HFE A;  2XQ9 A;  3PMZ A;  4AFG A;  3P50 A;  3UU8 A;  4BFQ A;  2YKS A;  3P4W A;  4HFB A;  4LMK A;  2XNU A;  3TLU A;  4COF A;  4ZZC A;  2XZ6 A;  5AFK A;  3WIP A;  3U8K A;  3U8J A;  2QC1 B;  3WTM A;  4B5D A;  5HEJ A;  5JME A;  3C79 A;  4QH5 A;  4TWF A;  4ILC A;  5HEH A;  4ZK4 A;  4ZRU A;  2BG9 A;  3WTJ A;  2XQ5 A;  4Z91 A;  3RHW A;  5HEO A;  4UM3 P;  5AIN A;  3SQ6 A;  4HFC A;  4D01 A;  2ZJU A;  2XYS A;  4BQT A;  5KZU A;  4IL4 A;  2BG9 C;  5LG3 A;  3WTI A;  2YMD A;  4QAA A;  2WNJ A;  3IGQ A;  4UY2 A;  2YOE A;  3ZKR A;  4A97 A;  5TVC A;  3JAF A;  5AFL A;  2BR7 A;  3WTN A;  3LSV A;  3SQ9 A;  4LMJ A;  3TLT A;  2XQ6 A; 
#chains in the Genus database with same CATH topology
 5HCJ A;  2ZJV A;  5HCM A;  2BYS A;  2WZY A;  3RIF A;  3GUA A;  5BRX A;  4F8H A;  4A98 A;  2Y57 A;  3UQ7 A;  3SH1 A;  3EHZ A;  4QH4 A;  3UU6 A;  5IUX A;  5J5H A;  2XQA A;  4TWD A;  2XZ5 A;  2PGZ A;  3RI5 A;  5KE4 A;  4IRE A;  4WV9 A;  2YN6 A;  3U8L A;  4AFH A;  4EZ1 A;  5CO5 A;  3UUB A;  5AFH A;  5J5I A;  2W8F A;  2BG9 E;  2BYR A;  4NZB A;  5HEG A;  2XYT A;  5AFN A;  3EI0 A;  4QAB A;  4ILB A;  1UW6 A;  1UX2 A;  2Y7Y A;  4QAC A;  3ZDH A;  2UZ6 A;  2WNL A;  2XNT A;  4NPP A;  5BP0 A;  5CFB A;  4UM1 A;  5FJV A;  2XQ3 A;  4ZR6 A;  2BYN A;  5L4E A;  4UM3 A;  3WTO A;  4XK9 A;  4ZJS A;  3TLV A;  2BR8 A;  4TWH A;  2XQ4 A;  3U8M A;  3UQ4 A;  3UU5 A;  3RQW A;  3EAM A;  2BJ0 A;  4HFH A;  5HEU A;  3RIA A;  2BG9 B;  3TLW A;  5AFM A;  4HQP A;  2VL0 A;  4DBM A;  4PIR A;  5SYO A;  5LXB A;  2XNV A;  3WTH A;  3JAE A;  4TNV A;  4UM3 S;  4LML A;  4Z90 A;  4AFT A;  2WN9 A;  4IL9 A;  2Y58 A;  2Y56 A;  5L4H A;  3RQU A;  3SIO A;  3ZDG A;  5J5F A;  5J5G A;  4ZK1 A;  3JAD A;  2PH9 A;  4ILA A;  4FRR A;  4TNW A;  4ALX A;  4ZZB A;  5J0Z A;  3PEO A;  2X00 A;  3UU4 A;  5L47 A;  2Y54 A;  3T4M A;  5AFJ A;  2W8G A;  2BYP A;  4HFI A;  4XHE A;  4HFD A;  4ZJT A;  3TLS A;  2XQ8 A;  2XQ7 A;  2YME A;  2WNC A;  2BYQ A;  2C9T A;  4UXU A;  4QH1 A;  3WTL A;  1UV6 A;  3UU3 A;  5AFM B;  3U8N A;  5BW2 A;  3C84 A;  1I9B A;  3WTK A;  2X00 D;  4X5T A;  4HFE A;  2XQ9 A;  3PMZ A;  4AFG A;  3P50 A;  3UU8 A;  4BFQ A;  2YKS A;  3P4W A;  4HFB A;  4LMK A;  2XNU A;  3TLU A;  4COF A;  4ZZC A;  2XZ6 A;  5AFK A;  3WIP A;  3U8K A;  3U8J A;  2QC1 B;  3WTM A;  4B5D A;  5HEJ A;  5JME A;  3C79 A;  4QH5 A;  4TWF A;  4ILC A;  5HEH A;  4ZK4 A;  4ZRU A;  2BG9 A;  3WTJ A;  2XQ5 A;  4Z91 A;  3RHW A;  5HEO A;  4UM3 P;  5AIN A;  3SQ6 A;  4HFC A;  4D01 A;  2ZJU A;  2XYS A;  4BQT A;  5KZU A;  4IL4 A;  2BG9 C;  5LG3 A;  3WTI A;  2YMD A;  4QAA A;  2WNJ A;  3IGQ A;  4UY2 A;  2YOE A;  3ZKR A;  4A97 A;  5TVC A;  3JAF A;  5AFL A;  2BR7 A;  3WTN A;  3LSV A;  3SQ9 A;  4LMJ A;  3TLT A;  2XQ6 A; 
#chains in the Genus database with same CATH homology
 5HCJ A;  2ZJV A;  5HCM A;  2BYS A;  2WZY A;  3RIF A;  3GUA A;  5BRX A;  4F8H A;  4A98 A;  2Y57 A;  3UQ7 A;  3SH1 A;  3EHZ A;  4QH4 A;  3UU6 A;  5IUX A;  5J5H A;  2XQA A;  4TWD A;  2XZ5 A;  2PGZ A;  3RI5 A;  5KE4 A;  4IRE A;  4WV9 A;  2YN6 A;  3U8L A;  4AFH A;  4EZ1 A;  5CO5 A;  3UUB A;  5AFH A;  5J5I A;  2W8F A;  2BG9 E;  2BYR A;  4NZB A;  5HEG A;  2XYT A;  5AFN A;  3EI0 A;  4QAB A;  4ILB A;  1UW6 A;  1UX2 A;  2Y7Y A;  4QAC A;  3ZDH A;  2UZ6 A;  2WNL A;  2XNT A;  4NPP A;  5BP0 A;  5CFB A;  4UM1 A;  5FJV A;  2XQ3 A;  4ZR6 A;  2BYN A;  5L4E A;  4UM3 A;  3WTO A;  4XK9 A;  4ZJS A;  3TLV A;  2BR8 A;  4TWH A;  2XQ4 A;  3U8M A;  3UQ4 A;  3UU5 A;  3RQW A;  3EAM A;  2BJ0 A;  4HFH A;  5HEU A;  3RIA A;  2BG9 B;  3TLW A;  5AFM A;  4HQP A;  2VL0 A;  4DBM A;  4PIR A;  5SYO A;  5LXB A;  2XNV A;  3WTH A;  3JAE A;  4TNV A;  4UM3 S;  4LML A;  4Z90 A;  4AFT A;  2WN9 A;  4IL9 A;  2Y58 A;  2Y56 A;  5L4H A;  3RQU A;  3SIO A;  3ZDG A;  5J5F A;  5J5G A;  4ZK1 A;  3JAD A;  2PH9 A;  4ILA A;  4FRR A;  4TNW A;  4ALX A;  4ZZB A;  5J0Z A;  3PEO A;  2X00 A;  3UU4 A;  5L47 A;  2Y54 A;  3T4M A;  5AFJ A;  2W8G A;  2BYP A;  4HFI A;  4XHE A;  4HFD A;  4ZJT A;  3TLS A;  2XQ8 A;  2XQ7 A;  2YME A;  2WNC A;  2BYQ A;  2C9T A;  4UXU A;  4QH1 A;  3WTL A;  1UV6 A;  3UU3 A;  5AFM B;  3U8N A;  5BW2 A;  3C84 A;  1I9B A;  3WTK A;  2X00 D;  4X5T A;  4HFE A;  2XQ9 A;  3PMZ A;  4AFG A;  3P50 A;  3UU8 A;  4BFQ A;  2YKS A;  3P4W A;  4HFB A;  4LMK A;  2XNU A;  3TLU A;  4COF A;  4ZZC A;  2XZ6 A;  5AFK A;  3WIP A;  3U8K A;  3U8J A;  2QC1 B;  3WTM A;  4B5D A;  5HEJ A;  5JME A;  3C79 A;  4QH5 A;  4TWF A;  4ILC A;  5HEH A;  4ZK4 A;  4ZRU A;  2BG9 A;  3WTJ A;  2XQ5 A;  4Z91 A;  3RHW A;  5HEO A;  4UM3 P;  5AIN A;  3SQ6 A;  4HFC A;  4D01 A;  2ZJU A;  2XYS A;  4BQT A;  5KZU A;  4IL4 A;  2BG9 C;  5LG3 A;  3WTI A;  2YMD A;  4QAA A;  2WNJ A;  3IGQ A;  4UY2 A;  2YOE A;  3ZKR A;  4A97 A;  5TVC A;  3JAF A;  5AFL A;  2BR7 A;  3WTN A;  3LSV A;  3SQ9 A;  4LMJ A;  3TLT A;  2XQ6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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