2WNJA

Crystal structure of aplysia achbp in complex with dmxba
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
209
structure length
209
Chain Sequence
LHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Determinants for Interaction of Partial Agonists with Acetylcholine Binding Protein and Neuronal Alpha7 Nicotinic Acetylcholine Receptor.
pubmed doi rcsb
molecule tags Receptor
source organism Aplysia californica
molecule keywords SOLUBLE ACETYLCHOLINE RECEPTOR
total genus 52
structure length 209
sequence length 209
chains with identical sequence B, C, D, E
ec nomenclature
pdb deposition date 2009-07-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 2wnjA00
2XQ6A 4A98A 5AFMB 2BG9B 5AFJA 5L4EA 2XNTA 5L47A 2WNJA 4QH5A 3SH1A 4HFCA 4ZZCA 5AFNA 4TWFA 3TLVA 3P4WA 4QH1A 5HCMA 4BQTA 4F8HA 5HEOA 5L4HA 2BYQA 2XQ7A 4UM1A 2BR8A 4COFA 2XYSA 4IREA 2XQ8A 5AINA 4Z90A 4UM3P 4AFTA 3WTLA 2XNVA 4XHEA 3EHZA 3U8JA 4BFQA 3UQ7A 4D01A 3WIPA 3U8MA 2XQ4A 2ZJUA 2C9TA 2WNCA 2WN9A 4ZK4A 5BRXA 2VL0A 3RQUA 4QH4A 4XK9A 2WNLA 4FRRA 5TVCA 3WTJA 5J5HA 3SQ6A 3PEOA 4PIRA 3U8KA 5LG3A 3TLWA 2BG9E 3SIOA 2YMDA 5KE4A 4WV9A 2XQ3A 4ILAA 3WTMA 4TWDA 2W8GA 4LMKA 4HFBA 2XZ5A 2XQ5A 5IUXA 4TWHA 4HFIA 3WTIA 5AFLA 1UW6A 4TNVA 3C84A 2BG9C 4X5TA 3UQ4A 3UU4A 3JADA 3JAFA 4A97A 5HEGA 2YOEA 5HEHA 1I9BA 5BP0A 3SQ9A 2Y7YA 4DBMA 4EZ1A 4IL9A 3IGQA 2BR7A 2YN6A 2X00D 5AFHA 4AFHA 3ZDHA 5AFKA 3C79A 3UUBA 2BJ0A 4ZJSA 3UU8A 4ALXA 3JAEA 3RI5A 4NZBA 4QACA 3TLSA 4HFDA 4ILBA 1UV6A 3GUAA 2UZ6A 5CO5A 2Y56A 3P50A 4ZR6A 3RQWA 2BYSA 4LMLA 2X00A 3RIAA 2ZJVA 3EAMA 3TLTA 2PH9A 4UM3S 4QABA 2Y54A 3T4MA 3UU3A 3ZKRA 2XNUA 4AFGA 2Y57A 2XYTA 2XZ6A 5HEUA 5J5GA 3UU5A 3ZDGA 2BYRA 2BYPA 5LXBA 5J5FA 5J0ZA 4ZK1A 4Z91A 2BYNA 2PGZA 4HFEA 3RIFA 2XQ9A 2YMEA 5JMEA 4HFHA 5FJVA 4ZRUA 3WTKA 4ZZBA 5J5IA 4TNWA 2W8FA 3EI0A 2BG9A 5HCJA 5SYOA 4HQPA 5AFMA 5HEJA 3TLUA 3LSVA 3PMZA 3UU6A 5CFBA 2QC1B 2WZYA 4UM3A 3RHWA 3WTOA 1UX2A 4B5DA 4UY2A 2XQAA 4IL4A 4QAAA 4ZJTA 3U8LA 2Y58A 3U8NA 4ILCA 3WTNA 2YKSA 5BW2A 5KZUA 3WTHA 4NPPA 4UXUA 4LMJA
chains in the Genus database with same CATH superfamily
2XQ6A 4A98A 5AFMB 2BG9B 5AFJA 5L4EA 2XNTA 5L47A 2WNJA 4QH5A 3SH1A 4HFCA 4ZZCA 5AFNA 4TWFA 3TLVA 3P4WA 4QH1A 5HCMA 4BQTA 4F8HA 5HEOA 5L4HA 2BYQA 2XQ7A 4UM1A 2BR8A 4COFA 2XYSA 4IREA 2XQ8A 5AINA 4Z90A 4UM3P 4AFTA 3WTLA 2XNVA 4XHEA 3EHZA 3U8JA 4BFQA 3UQ7A 4D01A 3WIPA 3U8MA 2XQ4A 2ZJUA 2C9TA 2WNCA 2WN9A 4ZK4A 5BRXA 2VL0A 3RQUA 4QH4A 4XK9A 2WNLA 4FRRA 5TVCA 3WTJA 5J5HA 3SQ6A 3PEOA 4PIRA 3U8KA 5LG3A 3TLWA 2BG9E 3SIOA 2YMDA 5KE4A 4WV9A 2XQ3A 4ILAA 3WTMA 4TWDA 2W8GA 4LMKA 4HFBA 2XZ5A 2XQ5A 5IUXA 4TWHA 4HFIA 3WTIA 5AFLA 1UW6A 4TNVA 3C84A 2BG9C 4X5TA 3UQ4A 3UU4A 3JADA 3JAFA 4A97A 5HEGA 2YOEA 5HEHA 1I9BA 5BP0A 3SQ9A 2Y7YA 4DBMA 4EZ1A 4IL9A 3IGQA 2BR7A 2YN6A 2X00D 5AFHA 4AFHA 3ZDHA 5AFKA 3C79A 3UUBA 2BJ0A 4ZJSA 3UU8A 4ALXA 3JAEA 3RI5A 4NZBA 4QACA 3TLSA 4HFDA 4ILBA 1UV6A 3GUAA 2UZ6A 5CO5A 2Y56A 3P50A 4ZR6A 3RQWA 2BYSA 4LMLA 2X00A 3RIAA 2ZJVA 3EAMA 3TLTA 2PH9A 4UM3S 4QABA 2Y54A 3T4MA 3UU3A 3ZKRA 2XNUA 4AFGA 2Y57A 2XYTA 2XZ6A 5HEUA 5J5GA 3UU5A 3ZDGA 2BYRA 2BYPA 5LXBA 5J5FA 5J0ZA 4ZK1A 4Z91A 2BYNA 2PGZA 4HFEA 3RIFA 2XQ9A 2YMEA 5JMEA 4HFHA 5FJVA 4ZRUA 3WTKA 4ZZBA 5J5IA 4TNWA 2W8FA 3EI0A 2BG9A 5HCJA 5SYOA 4HQPA 5AFMA 5HEJA 3TLUA 3LSVA 3PMZA 3UU6A 5CFBA 2QC1B 2WZYA 4UM3A 3RHWA 3WTOA 1UX2A 4B5DA 4UY2A 2XQAA 4IL4A 4QAAA 4ZJTA 3U8LA 2Y58A 3U8NA 4ILCA 3WTNA 2YKSA 5BW2A 5KZUA 3WTHA 4NPPA 4UXUA 4LMJA
chains in the Genus database with same CATH topology
2XQ6A 4A98A 5AFMB 2BG9B 5AFJA 5L4EA 2XNTA 5L47A 2WNJA 4QH5A 3SH1A 4HFCA 4ZZCA 5AFNA 4TWFA 3TLVA 3P4WA 4QH1A 5HCMA 4BQTA 4F8HA 5HEOA 5L4HA 2BYQA 2XQ7A 4UM1A 2BR8A 4COFA 2XYSA 4IREA 2XQ8A 5AINA 4Z90A 4UM3P 4AFTA 3WTLA 2XNVA 4XHEA 3EHZA 3U8JA 4BFQA 3UQ7A 4D01A 3WIPA 3U8MA 2XQ4A 2ZJUA 2C9TA 2WNCA 2WN9A 4ZK4A 5BRXA 2VL0A 3RQUA 4QH4A 4XK9A 2WNLA 4FRRA 5TVCA 3WTJA 5J5HA 3SQ6A 3PEOA 4PIRA 3U8KA 5LG3A 3TLWA 2BG9E 3SIOA 2YMDA 5KE4A 4WV9A 2XQ3A 4ILAA 3WTMA 4TWDA 2W8GA 4LMKA 4HFBA 2XZ5A 2XQ5A 5IUXA 4TWHA 4HFIA 3WTIA 5AFLA 1UW6A 4TNVA 3C84A 2BG9C 4X5TA 3UQ4A 3UU4A 3JADA 3JAFA 4A97A 5HEGA 2YOEA 5HEHA 1I9BA 5BP0A 3SQ9A 2Y7YA 4DBMA 4EZ1A 4IL9A 3IGQA 2BR7A 2YN6A 2X00D 5AFHA 4AFHA 3ZDHA 5AFKA 3C79A 3UUBA 2BJ0A 4ZJSA 3UU8A 4ALXA 3JAEA 3RI5A 4NZBA 4QACA 3TLSA 4HFDA 4ILBA 1UV6A 3GUAA 2UZ6A 5CO5A 2Y56A 3P50A 4ZR6A 3RQWA 2BYSA 4LMLA 2X00A 3RIAA 2ZJVA 3EAMA 3TLTA 2PH9A 4UM3S 4QABA 2Y54A 3T4MA 3UU3A 3ZKRA 2XNUA 4AFGA 2Y57A 2XYTA 2XZ6A 5HEUA 5J5GA 3UU5A 3ZDGA 2BYRA 2BYPA 5LXBA 5J5FA 5J0ZA 4ZK1A 4Z91A 2BYNA 2PGZA 4HFEA 3RIFA 2XQ9A 2YMEA 5JMEA 4HFHA 5FJVA 4ZRUA 3WTKA 4ZZBA 5J5IA 4TNWA 2W8FA 3EI0A 2BG9A 5HCJA 5SYOA 4HQPA 5AFMA 5HEJA 3TLUA 3LSVA 3PMZA 3UU6A 5CFBA 2QC1B 2WZYA 4UM3A 3RHWA 3WTOA 1UX2A 4B5DA 4UY2A 2XQAA 4IL4A 4QAAA 4ZJTA 3U8LA 2Y58A 3U8NA 4ILCA 3WTNA 2YKSA 5BW2A 5KZUA 3WTHA 4NPPA 4UXUA 4LMJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XQ6 A;  4A98 A;  5AFM B;  2BG9 B;  5AFJ A;  5L4E A;  2XNT A;  5L47 A;  2WNJ A;  4QH5 A;  3SH1 A;  4HFC A;  4ZZC A;  5AFN A;  4TWF A;  3TLV A;  3P4W A;  4QH1 A;  5HCM A;  4BQT A;  4F8H A;  5HEO A;  5L4H A;  2BYQ A;  2XQ7 A;  4UM1 A;  2BR8 A;  4COF A;  2XYS A;  4IRE A;  2XQ8 A;  5AIN A;  4Z90 A;  4UM3 P;  4AFT A;  3WTL A;  2XNV A;  4XHE A;  3EHZ A;  3U8J A;  4BFQ A;  3UQ7 A;  4D01 A;  3WIP A;  3U8M A;  2XQ4 A;  2ZJU A;  2C9T A;  2WNC A;  2WN9 A;  4ZK4 A;  5BRX A;  2VL0 A;  3RQU A;  4QH4 A;  4XK9 A;  2WNL A;  4FRR A;  5TVC A;  3WTJ A;  5J5H A;  3SQ6 A;  3PEO A;  4PIR A;  3U8K A;  5LG3 A;  3TLW A;  2BG9 E;  3SIO A;  2YMD A;  5KE4 A;  4WV9 A;  2XQ3 A;  4ILA A;  3WTM A;  4TWD A;  2W8G A;  4LMK A;  4HFB A;  2XZ5 A;  2XQ5 A;  5IUX A;  4TWH A;  4HFI A;  3WTI A;  5AFL A;  1UW6 A;  4TNV A;  3C84 A;  2BG9 C;  4X5T A;  3UQ4 A;  3UU4 A;  3JAD A;  3JAF A;  4A97 A;  5HEG A;  2YOE A;  5HEH A;  1I9B A;  5BP0 A;  3SQ9 A;  2Y7Y A;  4DBM A;  4EZ1 A;  4IL9 A;  3IGQ A;  2BR7 A;  2YN6 A;  2X00 D;  5AFH A;  4AFH A;  3ZDH A;  5AFK A;  3C79 A;  3UUB A;  2BJ0 A;  4ZJS A;  3UU8 A;  4ALX A;  3JAE A;  3RI5 A;  4NZB A;  4QAC A;  3TLS A;  4HFD A;  4ILB A;  1UV6 A;  3GUA A;  2UZ6 A;  5CO5 A;  2Y56 A;  3P50 A;  4ZR6 A;  3RQW A;  2BYS A;  4LML A;  2X00 A;  3RIA A;  2ZJV A;  3EAM A;  3TLT A;  2PH9 A;  4UM3 S;  4QAB A;  2Y54 A;  3T4M A;  3UU3 A;  3ZKR A;  2XNU A;  4AFG A;  2Y57 A;  2XYT A;  2XZ6 A;  5HEU A;  5J5G A;  3UU5 A;  3ZDG A;  2BYR A;  2BYP A;  5LXB A;  5J5F A;  5J0Z A;  4ZK1 A;  4Z91 A;  2BYN A;  2PGZ A;  4HFE A;  3RIF A;  2XQ9 A;  2YME A;  5JME A;  4HFH A;  5FJV A;  4ZRU A;  3WTK A;  4ZZB A;  5J5I A;  4TNW A;  2W8F A;  3EI0 A;  2BG9 A;  5HCJ A;  5SYO A;  4HQP A;  5AFM A;  5HEJ A;  3TLU A;  3LSV A;  3PMZ A;  3UU6 A;  5CFB A;  2QC1 B;  2WZY A;  4UM3 A;  3RHW A;  3WTO A;  1UX2 A;  4B5D A;  4UY2 A;  2XQA A;  4IL4 A;  4QAA A;  4ZJT A;  3U8L A;  2Y58 A;  3U8N A;  4ILC A;  3WTN A;  2YKS A;  5BW2 A;  5KZU A;  3WTH A;  4NPP A;  4UXU A;  4LMJ A; 
#chains in the Genus database with same CATH topology
 2XQ6 A;  4A98 A;  5AFM B;  2BG9 B;  5AFJ A;  5L4E A;  2XNT A;  5L47 A;  2WNJ A;  4QH5 A;  3SH1 A;  4HFC A;  4ZZC A;  5AFN A;  4TWF A;  3TLV A;  3P4W A;  4QH1 A;  5HCM A;  4BQT A;  4F8H A;  5HEO A;  5L4H A;  2BYQ A;  2XQ7 A;  4UM1 A;  2BR8 A;  4COF A;  2XYS A;  4IRE A;  2XQ8 A;  5AIN A;  4Z90 A;  4UM3 P;  4AFT A;  3WTL A;  2XNV A;  4XHE A;  3EHZ A;  3U8J A;  4BFQ A;  3UQ7 A;  4D01 A;  3WIP A;  3U8M A;  2XQ4 A;  2ZJU A;  2C9T A;  2WNC A;  2WN9 A;  4ZK4 A;  5BRX A;  2VL0 A;  3RQU A;  4QH4 A;  4XK9 A;  2WNL A;  4FRR A;  5TVC A;  3WTJ A;  5J5H A;  3SQ6 A;  3PEO A;  4PIR A;  3U8K A;  5LG3 A;  3TLW A;  2BG9 E;  3SIO A;  2YMD A;  5KE4 A;  4WV9 A;  2XQ3 A;  4ILA A;  3WTM A;  4TWD A;  2W8G A;  4LMK A;  4HFB A;  2XZ5 A;  2XQ5 A;  5IUX A;  4TWH A;  4HFI A;  3WTI A;  5AFL A;  1UW6 A;  4TNV A;  3C84 A;  2BG9 C;  4X5T A;  3UQ4 A;  3UU4 A;  3JAD A;  3JAF A;  4A97 A;  5HEG A;  2YOE A;  5HEH A;  1I9B A;  5BP0 A;  3SQ9 A;  2Y7Y A;  4DBM A;  4EZ1 A;  4IL9 A;  3IGQ A;  2BR7 A;  2YN6 A;  2X00 D;  5AFH A;  4AFH A;  3ZDH A;  5AFK A;  3C79 A;  3UUB A;  2BJ0 A;  4ZJS A;  3UU8 A;  4ALX A;  3JAE A;  3RI5 A;  4NZB A;  4QAC A;  3TLS A;  4HFD A;  4ILB A;  1UV6 A;  3GUA A;  2UZ6 A;  5CO5 A;  2Y56 A;  3P50 A;  4ZR6 A;  3RQW A;  2BYS A;  4LML A;  2X00 A;  3RIA A;  2ZJV A;  3EAM A;  3TLT A;  2PH9 A;  4UM3 S;  4QAB A;  2Y54 A;  3T4M A;  3UU3 A;  3ZKR A;  2XNU A;  4AFG A;  2Y57 A;  2XYT A;  2XZ6 A;  5HEU A;  5J5G A;  3UU5 A;  3ZDG A;  2BYR A;  2BYP A;  5LXB A;  5J5F A;  5J0Z A;  4ZK1 A;  4Z91 A;  2BYN A;  2PGZ A;  4HFE A;  3RIF A;  2XQ9 A;  2YME A;  5JME A;  4HFH A;  5FJV A;  4ZRU A;  3WTK A;  4ZZB A;  5J5I A;  4TNW A;  2W8F A;  3EI0 A;  2BG9 A;  5HCJ A;  5SYO A;  4HQP A;  5AFM A;  5HEJ A;  3TLU A;  3LSV A;  3PMZ A;  3UU6 A;  5CFB A;  2QC1 B;  2WZY A;  4UM3 A;  3RHW A;  3WTO A;  1UX2 A;  4B5D A;  4UY2 A;  2XQA A;  4IL4 A;  4QAA A;  4ZJT A;  3U8L A;  2Y58 A;  3U8N A;  4ILC A;  3WTN A;  2YKS A;  5BW2 A;  5KZU A;  3WTH A;  4NPP A;  4UXU A;  4LMJ A; 
#chains in the Genus database with same CATH homology
 2XQ6 A;  4A98 A;  5AFM B;  2BG9 B;  5AFJ A;  5L4E A;  2XNT A;  5L47 A;  2WNJ A;  4QH5 A;  3SH1 A;  4HFC A;  4ZZC A;  5AFN A;  4TWF A;  3TLV A;  3P4W A;  4QH1 A;  5HCM A;  4BQT A;  4F8H A;  5HEO A;  5L4H A;  2BYQ A;  2XQ7 A;  4UM1 A;  2BR8 A;  4COF A;  2XYS A;  4IRE A;  2XQ8 A;  5AIN A;  4Z90 A;  4UM3 P;  4AFT A;  3WTL A;  2XNV A;  4XHE A;  3EHZ A;  3U8J A;  4BFQ A;  3UQ7 A;  4D01 A;  3WIP A;  3U8M A;  2XQ4 A;  2ZJU A;  2C9T A;  2WNC A;  2WN9 A;  4ZK4 A;  5BRX A;  2VL0 A;  3RQU A;  4QH4 A;  4XK9 A;  2WNL A;  4FRR A;  5TVC A;  3WTJ A;  5J5H A;  3SQ6 A;  3PEO A;  4PIR A;  3U8K A;  5LG3 A;  3TLW A;  2BG9 E;  3SIO A;  2YMD A;  5KE4 A;  4WV9 A;  2XQ3 A;  4ILA A;  3WTM A;  4TWD A;  2W8G A;  4LMK A;  4HFB A;  2XZ5 A;  2XQ5 A;  5IUX A;  4TWH A;  4HFI A;  3WTI A;  5AFL A;  1UW6 A;  4TNV A;  3C84 A;  2BG9 C;  4X5T A;  3UQ4 A;  3UU4 A;  3JAD A;  3JAF A;  4A97 A;  5HEG A;  2YOE A;  5HEH A;  1I9B A;  5BP0 A;  3SQ9 A;  2Y7Y A;  4DBM A;  4EZ1 A;  4IL9 A;  3IGQ A;  2BR7 A;  2YN6 A;  2X00 D;  5AFH A;  4AFH A;  3ZDH A;  5AFK A;  3C79 A;  3UUB A;  2BJ0 A;  4ZJS A;  3UU8 A;  4ALX A;  3JAE A;  3RI5 A;  4NZB A;  4QAC A;  3TLS A;  4HFD A;  4ILB A;  1UV6 A;  3GUA A;  2UZ6 A;  5CO5 A;  2Y56 A;  3P50 A;  4ZR6 A;  3RQW A;  2BYS A;  4LML A;  2X00 A;  3RIA A;  2ZJV A;  3EAM A;  3TLT A;  2PH9 A;  4UM3 S;  4QAB A;  2Y54 A;  3T4M A;  3UU3 A;  3ZKR A;  2XNU A;  4AFG A;  2Y57 A;  2XYT A;  2XZ6 A;  5HEU A;  5J5G A;  3UU5 A;  3ZDG A;  2BYR A;  2BYP A;  5LXB A;  5J5F A;  5J0Z A;  4ZK1 A;  4Z91 A;  2BYN A;  2PGZ A;  4HFE A;  3RIF A;  2XQ9 A;  2YME A;  5JME A;  4HFH A;  5FJV A;  4ZRU A;  3WTK A;  4ZZB A;  5J5I A;  4TNW A;  2W8F A;  3EI0 A;  2BG9 A;  5HCJ A;  5SYO A;  4HQP A;  5AFM A;  5HEJ A;  3TLU A;  3LSV A;  3PMZ A;  3UU6 A;  5CFB A;  2QC1 B;  2WZY A;  4UM3 A;  3RHW A;  3WTO A;  1UX2 A;  4B5D A;  4UY2 A;  2XQA A;  4IL4 A;  4QAA A;  4ZJT A;  3U8L A;  2Y58 A;  3U8N A;  4ILC A;  3WTN A;  2YKS A;  5BW2 A;  5KZU A;  3WTH A;  4NPP A;  4UXU A;  4LMJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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