2WNJ | Genus

Total Genus 52

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	52
sequence length	209
structure length	209
Chain Sequence	LHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Receptor
source organism	Aplysia californica
publication title	Structural Determinants for Interaction of Partial Agonists with Acetylcholine Binding Protein and Neuronal Alpha7 Nicotinic Acetylcholine Receptor. pubmed doi rcsb
molecule keywords	SOLUBLE ACETYLCHOLINE RECEPTOR
total genus	52
structure length	209
sequence length	209
chains with identical sequence	B, C, D, E
ec nomenclature
pdb deposition date	2009-07-09

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF02931	Neur_chan_LBD	Neurotransmitter-gated ion-channel ligand binding domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.70.170.10	Mainly Beta	Distorted Sandwich	Acetylcholine Binding Protein; Chain: A,	Neurotransmitter-gated ion-channel ligand-binding domain	2wnjA00

2WN9A 4ILAA 4TNVA 3RI5A 4ILCA 5BW2A 5AFKA 2XZ6A 2XZ5A 3EAMA 3WTJA 2XNTA 3TLVA 3WTMA 5J5IA 2BG9E 4UM1A 5AFHA 4AFHA 5AFNA 4QABA 4AFTA 4ALXA 5L4EA 5LXBA 3P50A 2XQAA 4LMJA 3PMZA 4EZ1A 5AINA 2BG9B 4XHEA 2XNVA 2BR8A 3EI0A 4IL4A 2Y57A 2WNLA 3T4MA 3GUAA 5AFLA 2QC1B 5BRXA 4UY2A 2WNJA 5CFBA 4IL9A 3RQUA 4TNWA 4QH1A 2W8GA 1UX2A 5IUXA 3UU8A 2XQ8A 5JMEA 1UV6A 5AFMA 5CO5A 4TWDA 4D01A 3JAEA 3WTKA 4HQPA 3IGQA 3ZDHA 4X5TA 4UXUA 1UW6A 3SQ6A 4ZZBA 2W8FA 4ZZCA 4ZR6A 4Z90A 2WZYA 2ZJUA 4HFBA 2BR7A 2XQ9A 4TWFA 2YMDA 2BYPA 3PEOA 5HEGA 3RHWA 5J0ZA 5L4HA 2BYRA 5AFMB 2Y56A 2X00D 4QH4A 4XK9A 2XQ6A 5L47A 4NPPA 2Y7YA 3TLUA 3ZDGA 2ZJVA 4FRRA 4UM3A 3UUBA 3U8NA 4Z91A 3C79A 3TLSA 5HEHA 3WTOA 4DBMA 2YMEA 4PIRA 2PH9A 4F8HA 2YKSA 4HFDA 3JAFA 2XNUA 3WIPA 3P4WA 4B5DA 2YOEA 5J5HA 2XQ4A 2XYSA 5KZUA 3U8JA 4BFQA 5HEJA 4ZK1A 3TLWA 2BYNA 5BP0A 4LMKA 3UQ4A 2VL0A 4A97A 5J5GA 3U8KA 3ZKRA 2UZ6A 4UM3P 3UU6A 5FJVA 2Y54A 2BG9A 3WTLA 4IREA 4ZRUA 3UU5A 4ZJTA 2YN6A 5LG3A 3U8LA 2BYSA 4HFEA 4ZJSA 3LSVA 1I9BA 2BYQA 4QAAA 2XQ5A 4WV9A 3WTNA 2XQ3A 4LMLA 4AFGA 4BQTA 2BJ0A 5HEOA 3RIAA 3UU4A 3SQ9A 4UM3S 5AFJA 3UU3A 3SIOA 2PGZA 2Y58A 3SH1A 3JADA 2XYTA 4HFCA 3EHZA 3UQ7A 5TVCA 5KE4A 2XQ7A 3WTHA 3C84A 4HFHA 2WNCA 5HCMA 3WTIA 5J5FA 2C9TA 2X00A 5SYOA 4QH5A 4A98A 4ILBA 5HCJA 3RQWA 4QACA 4ZK4A 4NZBA 5HEUA 3RIFA 4HFIA 4TWHA 3TLTA 4COFA 2BG9C 3U8MA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 2WN9 A;  4ILA A;  4TNV A;  3RI5 A;  4ILC A;  5BW2 A;  5AFK A;  2XZ6 A;  2XZ5 A;  3EAM A;  3WTJ A;  2XNT A;  3TLV A;  3WTM A;  5J5I A;  2BG9 E;  4UM1 A;  5AFH A;  4AFH A;  5AFN A;  4QAB A;  4AFT A;  4ALX A;  5L4E A;  5LXB A;  3P50 A;  2XQA A;  4LMJ A;  3PMZ A;  4EZ1 A;  5AIN A;  2BG9 B;  4XHE A;  2XNV A;  2BR8 A;  3EI0 A;  4IL4 A;  2Y57 A;  2WNL A;  3T4M A;  3GUA A;  5AFL A;  2QC1 B;  5BRX A;  4UY2 A;  2WNJ A;  5CFB A;  4IL9 A;  3RQU A;  4TNW A;  4QH1 A;  2W8G A;  1UX2 A;  5IUX A;  3UU8 A;  2XQ8 A;  5JME A;  1UV6 A;  5AFM A;  5CO5 A;  4TWD A;  4D01 A;  3JAE A;  3WTK A;  4HQP A;  3IGQ A;  3ZDH A;  4X5T A;  4UXU A;  1UW6 A;  3SQ6 A;  4ZZB A;  2W8F A;  4ZZC A;  4ZR6 A;  4Z90 A;  2WZY A;  2ZJU A;  4HFB A;  2BR7 A;  2XQ9 A;  4TWF A;  2YMD A;  2BYP A;  3PEO A;  5HEG A;  3RHW A;  5J0Z A;  5L4H A;  2BYR A;  5AFM B;  2Y56 A;  2X00 D;  4QH4 A;  4XK9 A;  2XQ6 A;  5L47 A;  4NPP A;  2Y7Y A;  3TLU A;  3ZDG A;  2ZJV A;  4FRR A;  4UM3 A;  3UUB A;  3U8N A;  4Z91 A;  3C79 A;  3TLS A;  5HEH A;  3WTO A;  4DBM A;  2YME A;  4PIR A;  2PH9 A;  4F8H A;  2YKS A;  4HFD A;  3JAF A;  2XNU A;  3WIP A;  3P4W A;  4B5D A;  2YOE A;  5J5H A;  2XQ4 A;  2XYS A;  5KZU A;  3U8J A;  4BFQ A;  5HEJ A;  4ZK1 A;  3TLW A;  2BYN A;  5BP0 A;  4LMK A;  3UQ4 A;  2VL0 A;  4A97 A;  5J5G A;  3U8K A;  3ZKR A;  2UZ6 A;  4UM3 P;  3UU6 A;  5FJV A;  2Y54 A;  2BG9 A;  3WTL A;  4IRE A;  4ZRU A;  3UU5 A;  4ZJT A;  2YN6 A;  5LG3 A;  3U8L A;  2BYS A;  4HFE A;  4ZJS A;  3LSV A;  1I9B A;  2BYQ A;  4QAA A;  2XQ5 A;  4WV9 A;  3WTN A;  2XQ3 A;  4LML A;  4AFG A;  4BQT A;  2BJ0 A;  5HEO A;  3RIA A;  3UU4 A;  3SQ9 A;  4UM3 S;  5AFJ A;  3UU3 A;  3SIO A;  2PGZ A;  2Y58 A;  3SH1 A;  3JAD A;  2XYT A;  4HFC A;  3EHZ A;  3UQ7 A;  5TVC A;  5KE4 A;  2XQ7 A;  3WTH A;  3C84 A;  4HFH A;  2WNC A;  5HCM A;  3WTI A;  5J5F A;  2C9T A;  2X00 A;  5SYO A;  4QH5 A;  4A98 A;  4ILB A;  5HCJ A;  3RQW A;  4QAC A;  4ZK4 A;  4NZB A;  5HEU A;  3RIF A;  4HFI A;  4TWH A;  3TLT A;  4COF A;  2BG9 C;  3U8M A; 
#chains in the Genus database with same CATH topology
 2WN9 A;  4ILA A;  4TNV A;  3RI5 A;  4ILC A;  5BW2 A;  5AFK A;  2XZ6 A;  2XZ5 A;  3EAM A;  3WTJ A;  2XNT A;  3TLV A;  3WTM A;  5J5I A;  2BG9 E;  4UM1 A;  5AFH A;  4AFH A;  5AFN A;  4QAB A;  4AFT A;  4ALX A;  5L4E A;  5LXB A;  3P50 A;  2XQA A;  4LMJ A;  3PMZ A;  4EZ1 A;  5AIN A;  2BG9 B;  4XHE A;  2XNV A;  2BR8 A;  3EI0 A;  4IL4 A;  2Y57 A;  2WNL A;  3T4M A;  3GUA A;  5AFL A;  2QC1 B;  5BRX A;  4UY2 A;  2WNJ A;  5CFB A;  4IL9 A;  3RQU A;  4TNW A;  4QH1 A;  2W8G A;  1UX2 A;  5IUX A;  3UU8 A;  2XQ8 A;  5JME A;  1UV6 A;  5AFM A;  5CO5 A;  4TWD A;  4D01 A;  3JAE A;  3WTK A;  4HQP A;  3IGQ A;  3ZDH A;  4X5T A;  4UXU A;  1UW6 A;  3SQ6 A;  4ZZB A;  2W8F A;  4ZZC A;  4ZR6 A;  4Z90 A;  2WZY A;  2ZJU A;  4HFB A;  2BR7 A;  2XQ9 A;  4TWF A;  2YMD A;  2BYP A;  3PEO A;  5HEG A;  3RHW A;  5J0Z A;  5L4H A;  2BYR A;  5AFM B;  2Y56 A;  2X00 D;  4QH4 A;  4XK9 A;  2XQ6 A;  5L47 A;  4NPP A;  2Y7Y A;  3TLU A;  3ZDG A;  2ZJV A;  4FRR A;  4UM3 A;  3UUB A;  3U8N A;  4Z91 A;  3C79 A;  3TLS A;  5HEH A;  3WTO A;  4DBM A;  2YME A;  4PIR A;  2PH9 A;  4F8H A;  2YKS A;  4HFD A;  3JAF A;  2XNU A;  3WIP A;  3P4W A;  4B5D A;  2YOE A;  5J5H A;  2XQ4 A;  2XYS A;  5KZU A;  3U8J A;  4BFQ A;  5HEJ A;  4ZK1 A;  3TLW A;  2BYN A;  5BP0 A;  4LMK A;  3UQ4 A;  2VL0 A;  4A97 A;  5J5G A;  3U8K A;  3ZKR A;  2UZ6 A;  4UM3 P;  3UU6 A;  5FJV A;  2Y54 A;  2BG9 A;  3WTL A;  4IRE A;  4ZRU A;  3UU5 A;  4ZJT A;  2YN6 A;  5LG3 A;  3U8L A;  2BYS A;  4HFE A;  4ZJS A;  3LSV A;  1I9B A;  2BYQ A;  4QAA A;  2XQ5 A;  4WV9 A;  3WTN A;  2XQ3 A;  4LML A;  4AFG A;  4BQT A;  2BJ0 A;  5HEO A;  3RIA A;  3UU4 A;  3SQ9 A;  4UM3 S;  5AFJ A;  3UU3 A;  3SIO A;  2PGZ A;  2Y58 A;  3SH1 A;  3JAD A;  2XYT A;  4HFC A;  3EHZ A;  3UQ7 A;  5TVC A;  5KE4 A;  2XQ7 A;  3WTH A;  3C84 A;  4HFH A;  2WNC A;  5HCM A;  3WTI A;  5J5F A;  2C9T A;  2X00 A;  5SYO A;  4QH5 A;  4A98 A;  4ILB A;  5HCJ A;  3RQW A;  4QAC A;  4ZK4 A;  4NZB A;  5HEU A;  3RIF A;  4HFI A;  4TWH A;  3TLT A;  4COF A;  2BG9 C;  3U8M A; 
#chains in the Genus database with same CATH homology
 2WN9 A;  4ILA A;  4TNV A;  3RI5 A;  4ILC A;  5BW2 A;  5AFK A;  2XZ6 A;  2XZ5 A;  3EAM A;  3WTJ A;  2XNT A;  3TLV A;  3WTM A;  5J5I A;  2BG9 E;  4UM1 A;  5AFH A;  4AFH A;  5AFN A;  4QAB A;  4AFT A;  4ALX A;  5L4E A;  5LXB A;  3P50 A;  2XQA A;  4LMJ A;  3PMZ A;  4EZ1 A;  5AIN A;  2BG9 B;  4XHE A;  2XNV A;  2BR8 A;  3EI0 A;  4IL4 A;  2Y57 A;  2WNL A;  3T4M A;  3GUA A;  5AFL A;  2QC1 B;  5BRX A;  4UY2 A;  2WNJ A;  5CFB A;  4IL9 A;  3RQU A;  4TNW A;  4QH1 A;  2W8G A;  1UX2 A;  5IUX A;  3UU8 A;  2XQ8 A;  5JME A;  1UV6 A;  5AFM A;  5CO5 A;  4TWD A;  4D01 A;  3JAE A;  3WTK A;  4HQP A;  3IGQ A;  3ZDH A;  4X5T A;  4UXU A;  1UW6 A;  3SQ6 A;  4ZZB A;  2W8F A;  4ZZC A;  4ZR6 A;  4Z90 A;  2WZY A;  2ZJU A;  4HFB A;  2BR7 A;  2XQ9 A;  4TWF A;  2YMD A;  2BYP A;  3PEO A;  5HEG A;  3RHW A;  5J0Z A;  5L4H A;  2BYR A;  5AFM B;  2Y56 A;  2X00 D;  4QH4 A;  4XK9 A;  2XQ6 A;  5L47 A;  4NPP A;  2Y7Y A;  3TLU A;  3ZDG A;  2ZJV A;  4FRR A;  4UM3 A;  3UUB A;  3U8N A;  4Z91 A;  3C79 A;  3TLS A;  5HEH A;  3WTO A;  4DBM A;  2YME A;  4PIR A;  2PH9 A;  4F8H A;  2YKS A;  4HFD A;  3JAF A;  2XNU A;  3WIP A;  3P4W A;  4B5D A;  2YOE A;  5J5H A;  2XQ4 A;  2XYS A;  5KZU A;  3U8J A;  4BFQ A;  5HEJ A;  4ZK1 A;  3TLW A;  2BYN A;  5BP0 A;  4LMK A;  3UQ4 A;  2VL0 A;  4A97 A;  5J5G A;  3U8K A;  3ZKR A;  2UZ6 A;  4UM3 P;  3UU6 A;  5FJV A;  2Y54 A;  2BG9 A;  3WTL A;  4IRE A;  4ZRU A;  3UU5 A;  4ZJT A;  2YN6 A;  5LG3 A;  3U8L A;  2BYS A;  4HFE A;  4ZJS A;  3LSV A;  1I9B A;  2BYQ A;  4QAA A;  2XQ5 A;  4WV9 A;  3WTN A;  2XQ3 A;  4LML A;  4AFG A;  4BQT A;  2BJ0 A;  5HEO A;  3RIA A;  3UU4 A;  3SQ9 A;  4UM3 S;  5AFJ A;  3UU3 A;  3SIO A;  2PGZ A;  2Y58 A;  3SH1 A;  3JAD A;  2XYT A;  4HFC A;  3EHZ A;  3UQ7 A;  5TVC A;  5KE4 A;  2XQ7 A;  3WTH A;  3C84 A;  4HFH A;  2WNC A;  5HCM A;  3WTI A;  5J5F A;  2C9T A;  2X00 A;  5SYO A;  4QH5 A;  4A98 A;  4ILB A;  5HCJ A;  3RQW A;  4QAC A;  4ZK4 A;  4NZB A;  5HEU A;  3RIF A;  4HFI A;  4TWH A;  3TLT A;  4COF A;  2BG9 C;  3U8M A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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2WNJA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations