2WNLA

Crystal structure of aplysia achbp in complex with anabaseine
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
213
structure length
213
Chain Sequence
DDDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal alpha7 nicotinic acetylcholine receptor.
pubmed doi rcsb
molecule tags Receptor
source organism Aplysia californica
molecule keywords SOLUBLE ACETYLCHOLINE RECEPTOR
total genus 50
structure length 213
sequence length 213
chains with identical sequence B, C, D, E, F, G, H, I, J
ec nomenclature
pdb deposition date 2009-07-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 2wnlA00
2XQ9A 5HEHA 3IGQA 3WTHA 5BW2A 3TLTA 3T4MA 3GUAA 5TVCA 2XYTA 2YMDA 5SYOA 4D01A 2BJ0A 3WTKA 3C79A 5J5IA 1UX2A 2Y7YA 1I9BA 3EI0A 4ZZCA 5L47A 5L4HA 2ZJUA 4UM3A 2YOEA 2W8FA 4IL4A 5CO5A 2PH9A 4COFA 4IREA 3SIOA 3UU3A 4Z91A 2BYPA 2Y58A 4QACA 2XQ3A 3P50A 5FJVA 5J0ZA 2XZ5A 4LMKA 5HCJA 5LXBA 5AFLA 5L4EA 2XQ8A 2XYSA 4FRRA 2WNLA 5BP0A 4TNWA 4A98A 2VL0A 2XQ6A 4B5DA 3ZKRA 3U8JA 4WV9A 2XNUA 4HFBA 3TLSA 4ZK1A 5AFMB 3UU8A 5J5HA 4HFCA 3WTLA 4UM3S 4ZZBA 2PGZA 5AFKA 3PMZA 4UM3P 2XQAA 5HEUA 4ZJSA 5AFMA 2BR7A 4Z90A 3UQ7A 4LMJA 3P4WA 5HCMA 3RHWA 4UY2A 3SQ6A 2YKSA 5J5GA 5HEJA 3UU6A 4HQPA 4ILBA 1UV6A 3TLVA 5J5FA 2BG9C 4TNVA 3RQWA 3EHZA 4LMLA 4ZK4A 2BR8A 3WTNA 2Y54A 2XZ6A 3UU5A 4AFHA 4DBMA 3LSVA 2XNVA 4NPPA 2BYNA 4UM1A 3EAMA 4QH4A 3RIAA 4F8HA 2UZ6A 2WNCA 3WTMA 4BFQA 2C9TA 2X00D 2BG9E 3TLUA 2WN9A 4NZBA 3ZDGA 4HFDA 3UU4A 2QC1B 4QH5A 3RQUA 2BYQA 3U8KA 3ZDHA 5HEOA 2W8GA 1UW6A 3RI5A 4QH1A 3U8MA 5JMEA 5IUXA 2XQ7A 2YN6A 4X5TA 3TLWA 2BG9B 4HFHA 4XHEA 2X00A 4ZR6A 2WZYA 4PIRA 4QABA 3WIPA 3JAEA 2BYRA 3WTJA 4HFEA 4EZ1A 5HEGA 4TWDA 3UQ4A 3WTIA 4ALXA 2BG9A 3WTOA 5KE4A 4HFIA 5BRXA 3SH1A 5AINA 3PEOA 2Y56A 4ZRUA 4AFGA 5LG3A 3RIFA 4ILCA 4AFTA 4ILAA 4A97A 3C84A 2ZJVA 5KZUA 3JADA 3U8NA 4BQTA 4TWHA 2XQ5A 4XK9A 4IL9A 3SQ9A 2BYSA 5CFBA 5AFNA 4QAAA 5AFHA 2YMEA 4UXUA 2WNJA 2XNTA 4TWFA 5AFJA 2XQ4A 2Y57A 3U8LA 3UUBA 4ZJTA 3JAFA
chains in the Genus database with same CATH superfamily
2XQ9A 5HEHA 3IGQA 3WTHA 5BW2A 3TLTA 3T4MA 3GUAA 5TVCA 2XYTA 2YMDA 5SYOA 4D01A 2BJ0A 3WTKA 3C79A 5J5IA 1UX2A 2Y7YA 1I9BA 3EI0A 4ZZCA 5L47A 5L4HA 2ZJUA 4UM3A 2YOEA 2W8FA 4IL4A 5CO5A 2PH9A 4COFA 4IREA 3SIOA 3UU3A 4Z91A 2BYPA 2Y58A 4QACA 2XQ3A 3P50A 5FJVA 5J0ZA 2XZ5A 4LMKA 5HCJA 5LXBA 5AFLA 5L4EA 2XQ8A 2XYSA 4FRRA 2WNLA 5BP0A 4TNWA 4A98A 2VL0A 2XQ6A 4B5DA 3ZKRA 3U8JA 4WV9A 2XNUA 4HFBA 3TLSA 4ZK1A 5AFMB 3UU8A 5J5HA 4HFCA 3WTLA 4UM3S 4ZZBA 2PGZA 5AFKA 3PMZA 4UM3P 2XQAA 5HEUA 4ZJSA 5AFMA 2BR7A 4Z90A 3UQ7A 4LMJA 3P4WA 5HCMA 3RHWA 4UY2A 3SQ6A 2YKSA 5J5GA 5HEJA 3UU6A 4HQPA 4ILBA 1UV6A 3TLVA 5J5FA 2BG9C 4TNVA 3RQWA 3EHZA 4LMLA 4ZK4A 2BR8A 3WTNA 2Y54A 2XZ6A 3UU5A 4AFHA 4DBMA 3LSVA 2XNVA 4NPPA 2BYNA 4UM1A 3EAMA 4QH4A 3RIAA 4F8HA 2UZ6A 2WNCA 3WTMA 4BFQA 2C9TA 2X00D 2BG9E 3TLUA 2WN9A 4NZBA 3ZDGA 4HFDA 3UU4A 2QC1B 4QH5A 3RQUA 2BYQA 3U8KA 3ZDHA 5HEOA 2W8GA 1UW6A 3RI5A 4QH1A 3U8MA 5JMEA 5IUXA 2XQ7A 2YN6A 4X5TA 3TLWA 2BG9B 4HFHA 4XHEA 2X00A 4ZR6A 2WZYA 4PIRA 4QABA 3WIPA 3JAEA 2BYRA 3WTJA 4HFEA 4EZ1A 5HEGA 4TWDA 3UQ4A 3WTIA 4ALXA 2BG9A 3WTOA 5KE4A 4HFIA 5BRXA 3SH1A 5AINA 3PEOA 2Y56A 4ZRUA 4AFGA 5LG3A 3RIFA 4ILCA 4AFTA 4ILAA 4A97A 3C84A 2ZJVA 5KZUA 3JADA 3U8NA 4BQTA 4TWHA 2XQ5A 4XK9A 4IL9A 3SQ9A 2BYSA 5CFBA 5AFNA 4QAAA 5AFHA 2YMEA 4UXUA 2WNJA 2XNTA 4TWFA 5AFJA 2XQ4A 2Y57A 3U8LA 3UUBA 4ZJTA 3JAFA
chains in the Genus database with same CATH topology
2XQ9A 5HEHA 3IGQA 3WTHA 5BW2A 3TLTA 3T4MA 3GUAA 5TVCA 2XYTA 2YMDA 5SYOA 4D01A 2BJ0A 3WTKA 3C79A 5J5IA 1UX2A 2Y7YA 1I9BA 3EI0A 4ZZCA 5L47A 5L4HA 2ZJUA 4UM3A 2YOEA 2W8FA 4IL4A 5CO5A 2PH9A 4COFA 4IREA 3SIOA 3UU3A 4Z91A 2BYPA 2Y58A 4QACA 2XQ3A 3P50A 5FJVA 5J0ZA 2XZ5A 4LMKA 5HCJA 5LXBA 5AFLA 5L4EA 2XQ8A 2XYSA 4FRRA 2WNLA 5BP0A 4TNWA 4A98A 2VL0A 2XQ6A 4B5DA 3ZKRA 3U8JA 4WV9A 2XNUA 4HFBA 3TLSA 4ZK1A 5AFMB 3UU8A 5J5HA 4HFCA 3WTLA 4UM3S 4ZZBA 2PGZA 5AFKA 3PMZA 4UM3P 2XQAA 5HEUA 4ZJSA 5AFMA 2BR7A 4Z90A 3UQ7A 4LMJA 3P4WA 5HCMA 3RHWA 4UY2A 3SQ6A 2YKSA 5J5GA 5HEJA 3UU6A 4HQPA 4ILBA 1UV6A 3TLVA 5J5FA 2BG9C 4TNVA 3RQWA 3EHZA 4LMLA 4ZK4A 2BR8A 3WTNA 2Y54A 2XZ6A 3UU5A 4AFHA 4DBMA 3LSVA 2XNVA 4NPPA 2BYNA 4UM1A 3EAMA 4QH4A 3RIAA 4F8HA 2UZ6A 2WNCA 3WTMA 4BFQA 2C9TA 2X00D 2BG9E 3TLUA 2WN9A 4NZBA 3ZDGA 4HFDA 3UU4A 2QC1B 4QH5A 3RQUA 2BYQA 3U8KA 3ZDHA 5HEOA 2W8GA 1UW6A 3RI5A 4QH1A 3U8MA 5JMEA 5IUXA 2XQ7A 2YN6A 4X5TA 3TLWA 2BG9B 4HFHA 4XHEA 2X00A 4ZR6A 2WZYA 4PIRA 4QABA 3WIPA 3JAEA 2BYRA 3WTJA 4HFEA 4EZ1A 5HEGA 4TWDA 3UQ4A 3WTIA 4ALXA 2BG9A 3WTOA 5KE4A 4HFIA 5BRXA 3SH1A 5AINA 3PEOA 2Y56A 4ZRUA 4AFGA 5LG3A 3RIFA 4ILCA 4AFTA 4ILAA 4A97A 3C84A 2ZJVA 5KZUA 3JADA 3U8NA 4BQTA 4TWHA 2XQ5A 4XK9A 4IL9A 3SQ9A 2BYSA 5CFBA 5AFNA 4QAAA 5AFHA 2YMEA 4UXUA 2WNJA 2XNTA 4TWFA 5AFJA 2XQ4A 2Y57A 3U8LA 3UUBA 4ZJTA 3JAFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XQ9 A;  5HEH A;  3IGQ A;  3WTH A;  5BW2 A;  3TLT A;  3T4M A;  3GUA A;  5TVC A;  2XYT A;  2YMD A;  5SYO A;  4D01 A;  2BJ0 A;  3WTK A;  3C79 A;  5J5I A;  1UX2 A;  2Y7Y A;  1I9B A;  3EI0 A;  4ZZC A;  5L47 A;  5L4H A;  2ZJU A;  4UM3 A;  2YOE A;  2W8F A;  4IL4 A;  5CO5 A;  2PH9 A;  4COF A;  4IRE A;  3SIO A;  3UU3 A;  4Z91 A;  2BYP A;  2Y58 A;  4QAC A;  2XQ3 A;  3P50 A;  5FJV A;  5J0Z A;  2XZ5 A;  4LMK A;  5HCJ A;  5LXB A;  5AFL A;  5L4E A;  2XQ8 A;  2XYS A;  4FRR A;  2WNL A;  5BP0 A;  4TNW A;  4A98 A;  2VL0 A;  2XQ6 A;  4B5D A;  3ZKR A;  3U8J A;  4WV9 A;  2XNU A;  4HFB A;  3TLS A;  4ZK1 A;  5AFM B;  3UU8 A;  5J5H A;  4HFC A;  3WTL A;  4UM3 S;  4ZZB A;  2PGZ A;  5AFK A;  3PMZ A;  4UM3 P;  2XQA A;  5HEU A;  4ZJS A;  5AFM A;  2BR7 A;  4Z90 A;  3UQ7 A;  4LMJ A;  3P4W A;  5HCM A;  3RHW A;  4UY2 A;  3SQ6 A;  2YKS A;  5J5G A;  5HEJ A;  3UU6 A;  4HQP A;  4ILB A;  1UV6 A;  3TLV A;  5J5F A;  2BG9 C;  4TNV A;  3RQW A;  3EHZ A;  4LML A;  4ZK4 A;  2BR8 A;  3WTN A;  2Y54 A;  2XZ6 A;  3UU5 A;  4AFH A;  4DBM A;  3LSV A;  2XNV A;  4NPP A;  2BYN A;  4UM1 A;  3EAM A;  4QH4 A;  3RIA A;  4F8H A;  2UZ6 A;  2WNC A;  3WTM A;  4BFQ A;  2C9T A;  2X00 D;  2BG9 E;  3TLU A;  2WN9 A;  4NZB A;  3ZDG A;  4HFD A;  3UU4 A;  2QC1 B;  4QH5 A;  3RQU A;  2BYQ A;  3U8K A;  3ZDH A;  5HEO A;  2W8G A;  1UW6 A;  3RI5 A;  4QH1 A;  3U8M A;  5JME A;  5IUX A;  2XQ7 A;  2YN6 A;  4X5T A;  3TLW A;  2BG9 B;  4HFH A;  4XHE A;  2X00 A;  4ZR6 A;  2WZY A;  4PIR A;  4QAB A;  3WIP A;  3JAE A;  2BYR A;  3WTJ A;  4HFE A;  4EZ1 A;  5HEG A;  4TWD A;  3UQ4 A;  3WTI A;  4ALX A;  2BG9 A;  3WTO A;  5KE4 A;  4HFI A;  5BRX A;  3SH1 A;  5AIN A;  3PEO A;  2Y56 A;  4ZRU A;  4AFG A;  5LG3 A;  3RIF A;  4ILC A;  4AFT A;  4ILA A;  4A97 A;  3C84 A;  2ZJV A;  5KZU A;  3JAD A;  3U8N A;  4BQT A;  4TWH A;  2XQ5 A;  4XK9 A;  4IL9 A;  3SQ9 A;  2BYS A;  5CFB A;  5AFN A;  4QAA A;  5AFH A;  2YME A;  4UXU A;  2WNJ A;  2XNT A;  4TWF A;  5AFJ A;  2XQ4 A;  2Y57 A;  3U8L A;  3UUB A;  4ZJT A;  3JAF A; 
#chains in the Genus database with same CATH topology
 2XQ9 A;  5HEH A;  3IGQ A;  3WTH A;  5BW2 A;  3TLT A;  3T4M A;  3GUA A;  5TVC A;  2XYT A;  2YMD A;  5SYO A;  4D01 A;  2BJ0 A;  3WTK A;  3C79 A;  5J5I A;  1UX2 A;  2Y7Y A;  1I9B A;  3EI0 A;  4ZZC A;  5L47 A;  5L4H A;  2ZJU A;  4UM3 A;  2YOE A;  2W8F A;  4IL4 A;  5CO5 A;  2PH9 A;  4COF A;  4IRE A;  3SIO A;  3UU3 A;  4Z91 A;  2BYP A;  2Y58 A;  4QAC A;  2XQ3 A;  3P50 A;  5FJV A;  5J0Z A;  2XZ5 A;  4LMK A;  5HCJ A;  5LXB A;  5AFL A;  5L4E A;  2XQ8 A;  2XYS A;  4FRR A;  2WNL A;  5BP0 A;  4TNW A;  4A98 A;  2VL0 A;  2XQ6 A;  4B5D A;  3ZKR A;  3U8J A;  4WV9 A;  2XNU A;  4HFB A;  3TLS A;  4ZK1 A;  5AFM B;  3UU8 A;  5J5H A;  4HFC A;  3WTL A;  4UM3 S;  4ZZB A;  2PGZ A;  5AFK A;  3PMZ A;  4UM3 P;  2XQA A;  5HEU A;  4ZJS A;  5AFM A;  2BR7 A;  4Z90 A;  3UQ7 A;  4LMJ A;  3P4W A;  5HCM A;  3RHW A;  4UY2 A;  3SQ6 A;  2YKS A;  5J5G A;  5HEJ A;  3UU6 A;  4HQP A;  4ILB A;  1UV6 A;  3TLV A;  5J5F A;  2BG9 C;  4TNV A;  3RQW A;  3EHZ A;  4LML A;  4ZK4 A;  2BR8 A;  3WTN A;  2Y54 A;  2XZ6 A;  3UU5 A;  4AFH A;  4DBM A;  3LSV A;  2XNV A;  4NPP A;  2BYN A;  4UM1 A;  3EAM A;  4QH4 A;  3RIA A;  4F8H A;  2UZ6 A;  2WNC A;  3WTM A;  4BFQ A;  2C9T A;  2X00 D;  2BG9 E;  3TLU A;  2WN9 A;  4NZB A;  3ZDG A;  4HFD A;  3UU4 A;  2QC1 B;  4QH5 A;  3RQU A;  2BYQ A;  3U8K A;  3ZDH A;  5HEO A;  2W8G A;  1UW6 A;  3RI5 A;  4QH1 A;  3U8M A;  5JME A;  5IUX A;  2XQ7 A;  2YN6 A;  4X5T A;  3TLW A;  2BG9 B;  4HFH A;  4XHE A;  2X00 A;  4ZR6 A;  2WZY A;  4PIR A;  4QAB A;  3WIP A;  3JAE A;  2BYR A;  3WTJ A;  4HFE A;  4EZ1 A;  5HEG A;  4TWD A;  3UQ4 A;  3WTI A;  4ALX A;  2BG9 A;  3WTO A;  5KE4 A;  4HFI A;  5BRX A;  3SH1 A;  5AIN A;  3PEO A;  2Y56 A;  4ZRU A;  4AFG A;  5LG3 A;  3RIF A;  4ILC A;  4AFT A;  4ILA A;  4A97 A;  3C84 A;  2ZJV A;  5KZU A;  3JAD A;  3U8N A;  4BQT A;  4TWH A;  2XQ5 A;  4XK9 A;  4IL9 A;  3SQ9 A;  2BYS A;  5CFB A;  5AFN A;  4QAA A;  5AFH A;  2YME A;  4UXU A;  2WNJ A;  2XNT A;  4TWF A;  5AFJ A;  2XQ4 A;  2Y57 A;  3U8L A;  3UUB A;  4ZJT A;  3JAF A; 
#chains in the Genus database with same CATH homology
 2XQ9 A;  5HEH A;  3IGQ A;  3WTH A;  5BW2 A;  3TLT A;  3T4M A;  3GUA A;  5TVC A;  2XYT A;  2YMD A;  5SYO A;  4D01 A;  2BJ0 A;  3WTK A;  3C79 A;  5J5I A;  1UX2 A;  2Y7Y A;  1I9B A;  3EI0 A;  4ZZC A;  5L47 A;  5L4H A;  2ZJU A;  4UM3 A;  2YOE A;  2W8F A;  4IL4 A;  5CO5 A;  2PH9 A;  4COF A;  4IRE A;  3SIO A;  3UU3 A;  4Z91 A;  2BYP A;  2Y58 A;  4QAC A;  2XQ3 A;  3P50 A;  5FJV A;  5J0Z A;  2XZ5 A;  4LMK A;  5HCJ A;  5LXB A;  5AFL A;  5L4E A;  2XQ8 A;  2XYS A;  4FRR A;  2WNL A;  5BP0 A;  4TNW A;  4A98 A;  2VL0 A;  2XQ6 A;  4B5D A;  3ZKR A;  3U8J A;  4WV9 A;  2XNU A;  4HFB A;  3TLS A;  4ZK1 A;  5AFM B;  3UU8 A;  5J5H A;  4HFC A;  3WTL A;  4UM3 S;  4ZZB A;  2PGZ A;  5AFK A;  3PMZ A;  4UM3 P;  2XQA A;  5HEU A;  4ZJS A;  5AFM A;  2BR7 A;  4Z90 A;  3UQ7 A;  4LMJ A;  3P4W A;  5HCM A;  3RHW A;  4UY2 A;  3SQ6 A;  2YKS A;  5J5G A;  5HEJ A;  3UU6 A;  4HQP A;  4ILB A;  1UV6 A;  3TLV A;  5J5F A;  2BG9 C;  4TNV A;  3RQW A;  3EHZ A;  4LML A;  4ZK4 A;  2BR8 A;  3WTN A;  2Y54 A;  2XZ6 A;  3UU5 A;  4AFH A;  4DBM A;  3LSV A;  2XNV A;  4NPP A;  2BYN A;  4UM1 A;  3EAM A;  4QH4 A;  3RIA A;  4F8H A;  2UZ6 A;  2WNC A;  3WTM A;  4BFQ A;  2C9T A;  2X00 D;  2BG9 E;  3TLU A;  2WN9 A;  4NZB A;  3ZDG A;  4HFD A;  3UU4 A;  2QC1 B;  4QH5 A;  3RQU A;  2BYQ A;  3U8K A;  3ZDH A;  5HEO A;  2W8G A;  1UW6 A;  3RI5 A;  4QH1 A;  3U8M A;  5JME A;  5IUX A;  2XQ7 A;  2YN6 A;  4X5T A;  3TLW A;  2BG9 B;  4HFH A;  4XHE A;  2X00 A;  4ZR6 A;  2WZY A;  4PIR A;  4QAB A;  3WIP A;  3JAE A;  2BYR A;  3WTJ A;  4HFE A;  4EZ1 A;  5HEG A;  4TWD A;  3UQ4 A;  3WTI A;  4ALX A;  2BG9 A;  3WTO A;  5KE4 A;  4HFI A;  5BRX A;  3SH1 A;  5AIN A;  3PEO A;  2Y56 A;  4ZRU A;  4AFG A;  5LG3 A;  3RIF A;  4ILC A;  4AFT A;  4ILA A;  4A97 A;  3C84 A;  2ZJV A;  5KZU A;  3JAD A;  3U8N A;  4BQT A;  4TWH A;  2XQ5 A;  4XK9 A;  4IL9 A;  3SQ9 A;  2BYS A;  5CFB A;  5AFN A;  4QAA A;  5AFH A;  2YME A;  4UXU A;  2WNJ A;  2XNT A;  4TWF A;  5AFJ A;  2XQ4 A;  2Y57 A;  3U8L A;  3UUB A;  4ZJT A;  3JAF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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