2WZYA

Crystal structure of a-achbp in complex with 13-desmethyl spirolide c
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
212
structure length
211
Chain Sequence
DDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHSCCPEPYIDVNLVVKFRERR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Determinants in Phycotoxins and Achbp Conferring High Affinity Binding and Nicotinic Achr Antagonism.
pubmed doi rcsb
molecule tags Receptor
source organism Aplysia californica
molecule keywords SOLUBLE ACETYLCHOLINE RECEPTOR
total genus 45
structure length 211
sequence length 212
chains with identical sequence B, C, D, E, F, G, H, I, J
ec nomenclature
pdb deposition date 2009-12-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 2wzyA00
4UM1A 3SH1A 2W8GA 3WTLA 2XYTA 5J5GA 3WTOA 3U8KA 4EZ1A 2YKSA 4HFDA 5BP0A 4HQPA 5HEGA 3UQ7A 3JAEA 4HFBA 3WTJA 3GUAA 3PEOA 3C79A 5BW2A 2WNCA 2Y58A 2XQ6A 5L4EA 5TVCA 2WNLA 2BG9A 2BG9B 3WTMA 2BR8A 3LSVA 2XQ3A 3PMZA 2YMEA 3EAMA 2BG9E 2XNTA 3WTNA 4DBMA 2UZ6A 4QH1A 3UU8A 4AFGA 3U8NA 3UU3A 3P50A 4QH5A 5L4HA 2C9TA 4B5DA 5BRXA 4TWHA 4BQTA 2WZYA 5LG3A 2PH9A 3SQ9A 3WTHA 4ZJTA 4TWFA 2XNUA 3EI0A 2BG9C 3EHZA 2XYSA 5SYOA 3U8LA 4XK9A 4ZRUA 3TLUA 5AINA 1UX2A 4UM3S 5L47A 4BFQA 2XQ7A 2BYPA 4QABA 4HFCA 4XHEA 3RHWA 5AFMA 4TWDA 3WTKA 5AFMB 5HEHA 2YN6A 3P4WA 5FJVA 3TLSA 2ZJVA 2BYSA 2PGZA 2XZ5A 4HFIA 2BR7A 4LMLA 2BYQA 4LMKA 3UQ4A 4LMJA 5CO5A 4ZK4A 2WN9A 4HFHA 2BJ0A 4AFHA 5IUXA 4UY2A 3U8MA 1I9BA 3SIOA 4IL4A 4NPPA 4COFA 2Y57A 5AFJA 3IGQA 4TNWA 3RIFA 5HCMA 3UU6A 5J5FA 2QC1B 3WTIA 2VL0A 3U8JA 4UXUA 4Z90A 3ZDHA 3RQUA 4A98A 2XQ9A 2XQAA 2Y7YA 3SQ6A 3ZDGA 5JMEA 4UM3P 3JADA 3UUBA 2YMDA 2Y56A 3RI5A 4PIRA 2XNVA 3TLVA 1UV6A 5J5IA 5LXBA 4D01A 4ZZBA 5AFLA 4IL9A 3T4MA 4X5TA 5KE4A 4F8HA 5HEJA 4QH4A 4ILCA 5AFHA 3WIPA 4UM3A 3UU4A 4ZZCA 5HEUA 3ZKRA 4ZK1A 2XZ6A 3UU5A 3RQWA 2WNJA 4ILAA 4ALXA 2X00A 2YOEA 5CFBA 2W8FA 4AFTA 2BYRA 2XQ8A 3C84A 1UW6A 4ILBA 2X00D 4A97A 5HCJA 2BYNA 4IREA 4ZR6A 4QAAA 3JAFA 4TNVA 4WV9A 5HEOA 2Y54A 2ZJUA 4Z91A 4ZJSA 4QACA 3TLTA 5AFNA 2XQ5A 5J0ZA 5KZUA 3TLWA 4HFEA 4NZBA 4FRRA 5AFKA 2XQ4A 5J5HA 3RIAA
chains in the Genus database with same CATH superfamily
4UM1A 3SH1A 2W8GA 3WTLA 2XYTA 5J5GA 3WTOA 3U8KA 4EZ1A 2YKSA 4HFDA 5BP0A 4HQPA 5HEGA 3UQ7A 3JAEA 4HFBA 3WTJA 3GUAA 3PEOA 3C79A 5BW2A 2WNCA 2Y58A 2XQ6A 5L4EA 5TVCA 2WNLA 2BG9A 2BG9B 3WTMA 2BR8A 3LSVA 2XQ3A 3PMZA 2YMEA 3EAMA 2BG9E 2XNTA 3WTNA 4DBMA 2UZ6A 4QH1A 3UU8A 4AFGA 3U8NA 3UU3A 3P50A 4QH5A 5L4HA 2C9TA 4B5DA 5BRXA 4TWHA 4BQTA 2WZYA 5LG3A 2PH9A 3SQ9A 3WTHA 4ZJTA 4TWFA 2XNUA 3EI0A 2BG9C 3EHZA 2XYSA 5SYOA 3U8LA 4XK9A 4ZRUA 3TLUA 5AINA 1UX2A 4UM3S 5L47A 4BFQA 2XQ7A 2BYPA 4QABA 4HFCA 4XHEA 3RHWA 5AFMA 4TWDA 3WTKA 5AFMB 5HEHA 2YN6A 3P4WA 5FJVA 3TLSA 2ZJVA 2BYSA 2PGZA 2XZ5A 4HFIA 2BR7A 4LMLA 2BYQA 4LMKA 3UQ4A 4LMJA 5CO5A 4ZK4A 2WN9A 4HFHA 2BJ0A 4AFHA 5IUXA 4UY2A 3U8MA 1I9BA 3SIOA 4IL4A 4NPPA 4COFA 2Y57A 5AFJA 3IGQA 4TNWA 3RIFA 5HCMA 3UU6A 5J5FA 2QC1B 3WTIA 2VL0A 3U8JA 4UXUA 4Z90A 3ZDHA 3RQUA 4A98A 2XQ9A 2XQAA 2Y7YA 3SQ6A 3ZDGA 5JMEA 4UM3P 3JADA 3UUBA 2YMDA 2Y56A 3RI5A 4PIRA 2XNVA 3TLVA 1UV6A 5J5IA 5LXBA 4D01A 4ZZBA 5AFLA 4IL9A 3T4MA 4X5TA 5KE4A 4F8HA 5HEJA 4QH4A 4ILCA 5AFHA 3WIPA 4UM3A 3UU4A 4ZZCA 5HEUA 3ZKRA 4ZK1A 2XZ6A 3UU5A 3RQWA 2WNJA 4ILAA 4ALXA 2X00A 2YOEA 5CFBA 2W8FA 4AFTA 2BYRA 2XQ8A 3C84A 1UW6A 4ILBA 2X00D 4A97A 5HCJA 2BYNA 4IREA 4ZR6A 4QAAA 3JAFA 4TNVA 4WV9A 5HEOA 2Y54A 2ZJUA 4Z91A 4ZJSA 4QACA 3TLTA 5AFNA 2XQ5A 5J0ZA 5KZUA 3TLWA 4HFEA 4NZBA 4FRRA 5AFKA 2XQ4A 5J5HA 3RIAA
chains in the Genus database with same CATH topology
4UM1A 3SH1A 2W8GA 3WTLA 2XYTA 5J5GA 3WTOA 3U8KA 4EZ1A 2YKSA 4HFDA 5BP0A 4HQPA 5HEGA 3UQ7A 3JAEA 4HFBA 3WTJA 3GUAA 3PEOA 3C79A 5BW2A 2WNCA 2Y58A 2XQ6A 5L4EA 5TVCA 2WNLA 2BG9A 2BG9B 3WTMA 2BR8A 3LSVA 2XQ3A 3PMZA 2YMEA 3EAMA 2BG9E 2XNTA 3WTNA 4DBMA 2UZ6A 4QH1A 3UU8A 4AFGA 3U8NA 3UU3A 3P50A 4QH5A 5L4HA 2C9TA 4B5DA 5BRXA 4TWHA 4BQTA 2WZYA 5LG3A 2PH9A 3SQ9A 3WTHA 4ZJTA 4TWFA 2XNUA 3EI0A 2BG9C 3EHZA 2XYSA 5SYOA 3U8LA 4XK9A 4ZRUA 3TLUA 5AINA 1UX2A 4UM3S 5L47A 4BFQA 2XQ7A 2BYPA 4QABA 4HFCA 4XHEA 3RHWA 5AFMA 4TWDA 3WTKA 5AFMB 5HEHA 2YN6A 3P4WA 5FJVA 3TLSA 2ZJVA 2BYSA 2PGZA 2XZ5A 4HFIA 2BR7A 4LMLA 2BYQA 4LMKA 3UQ4A 4LMJA 5CO5A 4ZK4A 2WN9A 4HFHA 2BJ0A 4AFHA 5IUXA 4UY2A 3U8MA 1I9BA 3SIOA 4IL4A 4NPPA 4COFA 2Y57A 5AFJA 3IGQA 4TNWA 3RIFA 5HCMA 3UU6A 5J5FA 2QC1B 3WTIA 2VL0A 3U8JA 4UXUA 4Z90A 3ZDHA 3RQUA 4A98A 2XQ9A 2XQAA 2Y7YA 3SQ6A 3ZDGA 5JMEA 4UM3P 3JADA 3UUBA 2YMDA 2Y56A 3RI5A 4PIRA 2XNVA 3TLVA 1UV6A 5J5IA 5LXBA 4D01A 4ZZBA 5AFLA 4IL9A 3T4MA 4X5TA 5KE4A 4F8HA 5HEJA 4QH4A 4ILCA 5AFHA 3WIPA 4UM3A 3UU4A 4ZZCA 5HEUA 3ZKRA 4ZK1A 2XZ6A 3UU5A 3RQWA 2WNJA 4ILAA 4ALXA 2X00A 2YOEA 5CFBA 2W8FA 4AFTA 2BYRA 2XQ8A 3C84A 1UW6A 4ILBA 2X00D 4A97A 5HCJA 2BYNA 4IREA 4ZR6A 4QAAA 3JAFA 4TNVA 4WV9A 5HEOA 2Y54A 2ZJUA 4Z91A 4ZJSA 4QACA 3TLTA 5AFNA 2XQ5A 5J0ZA 5KZUA 3TLWA 4HFEA 4NZBA 4FRRA 5AFKA 2XQ4A 5J5HA 3RIAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UM1 A;  3SH1 A;  2W8G A;  3WTL A;  2XYT A;  5J5G A;  3WTO A;  3U8K A;  4EZ1 A;  2YKS A;  4HFD A;  5BP0 A;  4HQP A;  5HEG A;  3UQ7 A;  3JAE A;  4HFB A;  3WTJ A;  3GUA A;  3PEO A;  3C79 A;  5BW2 A;  2WNC A;  2Y58 A;  2XQ6 A;  5L4E A;  5TVC A;  2WNL A;  2BG9 A;  2BG9 B;  3WTM A;  2BR8 A;  3LSV A;  2XQ3 A;  3PMZ A;  2YME A;  3EAM A;  2BG9 E;  2XNT A;  3WTN A;  4DBM A;  2UZ6 A;  4QH1 A;  3UU8 A;  4AFG A;  3U8N A;  3UU3 A;  3P50 A;  4QH5 A;  5L4H A;  2C9T A;  4B5D A;  5BRX A;  4TWH A;  4BQT A;  2WZY A;  5LG3 A;  2PH9 A;  3SQ9 A;  3WTH A;  4ZJT A;  4TWF A;  2XNU A;  3EI0 A;  2BG9 C;  3EHZ A;  2XYS A;  5SYO A;  3U8L A;  4XK9 A;  4ZRU A;  3TLU A;  5AIN A;  1UX2 A;  4UM3 S;  5L47 A;  4BFQ A;  2XQ7 A;  2BYP A;  4QAB A;  4HFC A;  4XHE A;  3RHW A;  5AFM A;  4TWD A;  3WTK A;  5AFM B;  5HEH A;  2YN6 A;  3P4W A;  5FJV A;  3TLS A;  2ZJV A;  2BYS A;  2PGZ A;  2XZ5 A;  4HFI A;  2BR7 A;  4LML A;  2BYQ A;  4LMK A;  3UQ4 A;  4LMJ A;  5CO5 A;  4ZK4 A;  2WN9 A;  4HFH A;  2BJ0 A;  4AFH A;  5IUX A;  4UY2 A;  3U8M A;  1I9B A;  3SIO A;  4IL4 A;  4NPP A;  4COF A;  2Y57 A;  5AFJ A;  3IGQ A;  4TNW A;  3RIF A;  5HCM A;  3UU6 A;  5J5F A;  2QC1 B;  3WTI A;  2VL0 A;  3U8J A;  4UXU A;  4Z90 A;  3ZDH A;  3RQU A;  4A98 A;  2XQ9 A;  2XQA A;  2Y7Y A;  3SQ6 A;  3ZDG A;  5JME A;  4UM3 P;  3JAD A;  3UUB A;  2YMD A;  2Y56 A;  3RI5 A;  4PIR A;  2XNV A;  3TLV A;  1UV6 A;  5J5I A;  5LXB A;  4D01 A;  4ZZB A;  5AFL A;  4IL9 A;  3T4M A;  4X5T A;  5KE4 A;  4F8H A;  5HEJ A;  4QH4 A;  4ILC A;  5AFH A;  3WIP A;  4UM3 A;  3UU4 A;  4ZZC A;  5HEU A;  3ZKR A;  4ZK1 A;  2XZ6 A;  3UU5 A;  3RQW A;  2WNJ A;  4ILA A;  4ALX A;  2X00 A;  2YOE A;  5CFB A;  2W8F A;  4AFT A;  2BYR A;  2XQ8 A;  3C84 A;  1UW6 A;  4ILB A;  2X00 D;  4A97 A;  5HCJ A;  2BYN A;  4IRE A;  4ZR6 A;  4QAA A;  3JAF A;  4TNV A;  4WV9 A;  5HEO A;  2Y54 A;  2ZJU A;  4Z91 A;  4ZJS A;  4QAC A;  3TLT A;  5AFN A;  2XQ5 A;  5J0Z A;  5KZU A;  3TLW A;  4HFE A;  4NZB A;  4FRR A;  5AFK A;  2XQ4 A;  5J5H A;  3RIA A; 
#chains in the Genus database with same CATH topology
 4UM1 A;  3SH1 A;  2W8G A;  3WTL A;  2XYT A;  5J5G A;  3WTO A;  3U8K A;  4EZ1 A;  2YKS A;  4HFD A;  5BP0 A;  4HQP A;  5HEG A;  3UQ7 A;  3JAE A;  4HFB A;  3WTJ A;  3GUA A;  3PEO A;  3C79 A;  5BW2 A;  2WNC A;  2Y58 A;  2XQ6 A;  5L4E A;  5TVC A;  2WNL A;  2BG9 A;  2BG9 B;  3WTM A;  2BR8 A;  3LSV A;  2XQ3 A;  3PMZ A;  2YME A;  3EAM A;  2BG9 E;  2XNT A;  3WTN A;  4DBM A;  2UZ6 A;  4QH1 A;  3UU8 A;  4AFG A;  3U8N A;  3UU3 A;  3P50 A;  4QH5 A;  5L4H A;  2C9T A;  4B5D A;  5BRX A;  4TWH A;  4BQT A;  2WZY A;  5LG3 A;  2PH9 A;  3SQ9 A;  3WTH A;  4ZJT A;  4TWF A;  2XNU A;  3EI0 A;  2BG9 C;  3EHZ A;  2XYS A;  5SYO A;  3U8L A;  4XK9 A;  4ZRU A;  3TLU A;  5AIN A;  1UX2 A;  4UM3 S;  5L47 A;  4BFQ A;  2XQ7 A;  2BYP A;  4QAB A;  4HFC A;  4XHE A;  3RHW A;  5AFM A;  4TWD A;  3WTK A;  5AFM B;  5HEH A;  2YN6 A;  3P4W A;  5FJV A;  3TLS A;  2ZJV A;  2BYS A;  2PGZ A;  2XZ5 A;  4HFI A;  2BR7 A;  4LML A;  2BYQ A;  4LMK A;  3UQ4 A;  4LMJ A;  5CO5 A;  4ZK4 A;  2WN9 A;  4HFH A;  2BJ0 A;  4AFH A;  5IUX A;  4UY2 A;  3U8M A;  1I9B A;  3SIO A;  4IL4 A;  4NPP A;  4COF A;  2Y57 A;  5AFJ A;  3IGQ A;  4TNW A;  3RIF A;  5HCM A;  3UU6 A;  5J5F A;  2QC1 B;  3WTI A;  2VL0 A;  3U8J A;  4UXU A;  4Z90 A;  3ZDH A;  3RQU A;  4A98 A;  2XQ9 A;  2XQA A;  2Y7Y A;  3SQ6 A;  3ZDG A;  5JME A;  4UM3 P;  3JAD A;  3UUB A;  2YMD A;  2Y56 A;  3RI5 A;  4PIR A;  2XNV A;  3TLV A;  1UV6 A;  5J5I A;  5LXB A;  4D01 A;  4ZZB A;  5AFL A;  4IL9 A;  3T4M A;  4X5T A;  5KE4 A;  4F8H A;  5HEJ A;  4QH4 A;  4ILC A;  5AFH A;  3WIP A;  4UM3 A;  3UU4 A;  4ZZC A;  5HEU A;  3ZKR A;  4ZK1 A;  2XZ6 A;  3UU5 A;  3RQW A;  2WNJ A;  4ILA A;  4ALX A;  2X00 A;  2YOE A;  5CFB A;  2W8F A;  4AFT A;  2BYR A;  2XQ8 A;  3C84 A;  1UW6 A;  4ILB A;  2X00 D;  4A97 A;  5HCJ A;  2BYN A;  4IRE A;  4ZR6 A;  4QAA A;  3JAF A;  4TNV A;  4WV9 A;  5HEO A;  2Y54 A;  2ZJU A;  4Z91 A;  4ZJS A;  4QAC A;  3TLT A;  5AFN A;  2XQ5 A;  5J0Z A;  5KZU A;  3TLW A;  4HFE A;  4NZB A;  4FRR A;  5AFK A;  2XQ4 A;  5J5H A;  3RIA A; 
#chains in the Genus database with same CATH homology
 4UM1 A;  3SH1 A;  2W8G A;  3WTL A;  2XYT A;  5J5G A;  3WTO A;  3U8K A;  4EZ1 A;  2YKS A;  4HFD A;  5BP0 A;  4HQP A;  5HEG A;  3UQ7 A;  3JAE A;  4HFB A;  3WTJ A;  3GUA A;  3PEO A;  3C79 A;  5BW2 A;  2WNC A;  2Y58 A;  2XQ6 A;  5L4E A;  5TVC A;  2WNL A;  2BG9 A;  2BG9 B;  3WTM A;  2BR8 A;  3LSV A;  2XQ3 A;  3PMZ A;  2YME A;  3EAM A;  2BG9 E;  2XNT A;  3WTN A;  4DBM A;  2UZ6 A;  4QH1 A;  3UU8 A;  4AFG A;  3U8N A;  3UU3 A;  3P50 A;  4QH5 A;  5L4H A;  2C9T A;  4B5D A;  5BRX A;  4TWH A;  4BQT A;  2WZY A;  5LG3 A;  2PH9 A;  3SQ9 A;  3WTH A;  4ZJT A;  4TWF A;  2XNU A;  3EI0 A;  2BG9 C;  3EHZ A;  2XYS A;  5SYO A;  3U8L A;  4XK9 A;  4ZRU A;  3TLU A;  5AIN A;  1UX2 A;  4UM3 S;  5L47 A;  4BFQ A;  2XQ7 A;  2BYP A;  4QAB A;  4HFC A;  4XHE A;  3RHW A;  5AFM A;  4TWD A;  3WTK A;  5AFM B;  5HEH A;  2YN6 A;  3P4W A;  5FJV A;  3TLS A;  2ZJV A;  2BYS A;  2PGZ A;  2XZ5 A;  4HFI A;  2BR7 A;  4LML A;  2BYQ A;  4LMK A;  3UQ4 A;  4LMJ A;  5CO5 A;  4ZK4 A;  2WN9 A;  4HFH A;  2BJ0 A;  4AFH A;  5IUX A;  4UY2 A;  3U8M A;  1I9B A;  3SIO A;  4IL4 A;  4NPP A;  4COF A;  2Y57 A;  5AFJ A;  3IGQ A;  4TNW A;  3RIF A;  5HCM A;  3UU6 A;  5J5F A;  2QC1 B;  3WTI A;  2VL0 A;  3U8J A;  4UXU A;  4Z90 A;  3ZDH A;  3RQU A;  4A98 A;  2XQ9 A;  2XQA A;  2Y7Y A;  3SQ6 A;  3ZDG A;  5JME A;  4UM3 P;  3JAD A;  3UUB A;  2YMD A;  2Y56 A;  3RI5 A;  4PIR A;  2XNV A;  3TLV A;  1UV6 A;  5J5I A;  5LXB A;  4D01 A;  4ZZB A;  5AFL A;  4IL9 A;  3T4M A;  4X5T A;  5KE4 A;  4F8H A;  5HEJ A;  4QH4 A;  4ILC A;  5AFH A;  3WIP A;  4UM3 A;  3UU4 A;  4ZZC A;  5HEU A;  3ZKR A;  4ZK1 A;  2XZ6 A;  3UU5 A;  3RQW A;  2WNJ A;  4ILA A;  4ALX A;  2X00 A;  2YOE A;  5CFB A;  2W8F A;  4AFT A;  2BYR A;  2XQ8 A;  3C84 A;  1UW6 A;  4ILB A;  2X00 D;  4A97 A;  5HCJ A;  2BYN A;  4IRE A;  4ZR6 A;  4QAA A;  3JAF A;  4TNV A;  4WV9 A;  5HEO A;  2Y54 A;  2ZJU A;  4Z91 A;  4ZJS A;  4QAC A;  3TLT A;  5AFN A;  2XQ5 A;  5J0Z A;  5KZU A;  3TLW A;  4HFE A;  4NZB A;  4FRR A;  5AFK A;  2XQ4 A;  5J5H A;  3RIA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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