2X00D

Crystal structure of a-achbp in complex with gymnodimine a
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
212
structure length
212
Chain Sequence
DDDLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Determinants in Phycotoxins and Achbp Conferring High Affinity Binding and Nicotinic Achr Antagonism.
pubmed doi rcsb
molecule tags Receptor
source organism Aplysia californica
molecule keywords SOLUBLE ACETYLCHOLINE RECEPTOR
total genus 54
structure length 212
sequence length 212
ec nomenclature
pdb deposition date 2009-12-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 2x00D00
3T4MA 3U8KA 5SYOA 2XQ9A 5L4EA 3RIFA 4QACA 2XQ3A 3IGQA 4ZK1A 4XK9A 5KE4A 2XQ7A 2Y54A 3WIPA 3EAMA 4UM3A 4TNVA 1I9BA 2WN9A 4BQTA 1UW6A 3TLUA 5AFJA 2BG9B 2YKSA 3RQWA 2XQ6A 4IREA 4QAAA 4ZRUA 2ZJVA 2XZ5A 3ZDGA 3U8JA 4NPPA 5J5HA 3C79A 4LMJA 4QABA 3TLWA 2BYQA 2W8FA 2XQAA 3UU3A 5AINA 2W8GA 5L4HA 3UUBA 2WZYA 2YOEA 5HEGA 3RI5A 1UV6A 5IUXA 5AFKA 2UZ6A 3UU8A 3RHWA 2YMEA 5HEHA 4HFIA 2WNLA 4AFGA 3JADA 4HFEA 4QH5A 3WTNA 2YMDA 3WTLA 2BG9C 3SH1A 4ZZBA 2BYPA 1UX2A 5TVCA 3TLTA 5HCJA 4ILBA 5L47A 2XYTA 4ALXA 2XQ8A 3PEOA 4FRRA 2PGZA 3TLSA 2X00D 4HFBA 3U8MA 3WTHA 4ZJTA 4AFHA 3EI0A 2BG9E 5AFHA 5HEUA 4QH1A 3UU4A 3JAEA 3PMZA 2BYNA 2XYSA 4UM1A 4ZK4A 4ZR6A 3WTKA 5CFBA 5HEJA 3RIAA 4ILCA 4UM3S 2BR8A 4Z91A 3SIOA 5LG3A 2Y7YA 4UXUA 2BYRA 2BYSA 2C9TA 5HEOA 2ZJUA 3SQ6A 3U8NA 5AFMA 4ZZCA 4TWHA 5FJVA 5J5IA 4DBMA 2XZ6A 2BR7A 4X5TA 5J5FA 4TWDA 4NZBA 2Y57A 5J0ZA 3UU5A 3U8LA 3ZKRA 5LXBA 3LSVA 5KZUA 4LMLA 4B5DA 2X00A 3WTJA 5HCMA 4QH4A 3EHZA 2VL0A 2QC1B 5JMEA 4LMKA 5BRXA 3P50A 4Z90A 5AFMB 4XHEA 2WNJA 5AFLA 2WNCA 4A98A 4HFDA 4ILAA 4AFTA 3TLVA 4BFQA 3WTIA 4D01A 4IL4A 3ZDHA 3RQUA 5BW2A 4WV9A 3UU6A 4TNWA 4EZ1A 4ZJSA 3P4WA 2YN6A 2XNVA 2XNTA 2PH9A 2XQ4A 2Y58A 2Y56A 3SQ9A 4A97A 4COFA 4TWFA 4F8HA 5AFNA 2XQ5A 4HFHA 2BJ0A 4IL9A 3WTMA 4UY2A 4HQPA 3JAFA 2XNUA 5J5GA 3WTOA 3UQ4A 3GUAA 4PIRA 5BP0A 3C84A 5CO5A 3UQ7A 2BG9A 4HFCA 4UM3P
chains in the Genus database with same CATH superfamily
3T4MA 3U8KA 5SYOA 2XQ9A 5L4EA 3RIFA 4QACA 2XQ3A 3IGQA 4ZK1A 4XK9A 5KE4A 2XQ7A 2Y54A 3WIPA 3EAMA 4UM3A 4TNVA 1I9BA 2WN9A 4BQTA 1UW6A 3TLUA 5AFJA 2BG9B 2YKSA 3RQWA 2XQ6A 4IREA 4QAAA 4ZRUA 2ZJVA 2XZ5A 3ZDGA 3U8JA 4NPPA 5J5HA 3C79A 4LMJA 4QABA 3TLWA 2BYQA 2W8FA 2XQAA 3UU3A 5AINA 2W8GA 5L4HA 3UUBA 2WZYA 2YOEA 5HEGA 3RI5A 1UV6A 5IUXA 5AFKA 2UZ6A 3UU8A 3RHWA 2YMEA 5HEHA 4HFIA 2WNLA 4AFGA 3JADA 4HFEA 4QH5A 3WTNA 2YMDA 3WTLA 2BG9C 3SH1A 4ZZBA 2BYPA 1UX2A 5TVCA 3TLTA 5HCJA 4ILBA 5L47A 2XYTA 4ALXA 2XQ8A 3PEOA 4FRRA 2PGZA 3TLSA 2X00D 4HFBA 3U8MA 3WTHA 4ZJTA 4AFHA 3EI0A 2BG9E 5AFHA 5HEUA 4QH1A 3UU4A 3JAEA 3PMZA 2BYNA 2XYSA 4UM1A 4ZK4A 4ZR6A 3WTKA 5CFBA 5HEJA 3RIAA 4ILCA 4UM3S 2BR8A 4Z91A 3SIOA 5LG3A 2Y7YA 4UXUA 2BYRA 2BYSA 2C9TA 5HEOA 2ZJUA 3SQ6A 3U8NA 5AFMA 4ZZCA 4TWHA 5FJVA 5J5IA 4DBMA 2XZ6A 2BR7A 4X5TA 5J5FA 4TWDA 4NZBA 2Y57A 5J0ZA 3UU5A 3U8LA 3ZKRA 5LXBA 3LSVA 5KZUA 4LMLA 4B5DA 2X00A 3WTJA 5HCMA 4QH4A 3EHZA 2VL0A 2QC1B 5JMEA 4LMKA 5BRXA 3P50A 4Z90A 5AFMB 4XHEA 2WNJA 5AFLA 2WNCA 4A98A 4HFDA 4ILAA 4AFTA 3TLVA 4BFQA 3WTIA 4D01A 4IL4A 3ZDHA 3RQUA 5BW2A 4WV9A 3UU6A 4TNWA 4EZ1A 4ZJSA 3P4WA 2YN6A 2XNVA 2XNTA 2PH9A 2XQ4A 2Y58A 2Y56A 3SQ9A 4A97A 4COFA 4TWFA 4F8HA 5AFNA 2XQ5A 4HFHA 2BJ0A 4IL9A 3WTMA 4UY2A 4HQPA 3JAFA 2XNUA 5J5GA 3WTOA 3UQ4A 3GUAA 4PIRA 5BP0A 3C84A 5CO5A 3UQ7A 2BG9A 4HFCA 4UM3P
chains in the Genus database with same CATH topology
3T4MA 3U8KA 5SYOA 2XQ9A 5L4EA 3RIFA 4QACA 2XQ3A 3IGQA 4ZK1A 4XK9A 5KE4A 2XQ7A 2Y54A 3WIPA 3EAMA 4UM3A 4TNVA 1I9BA 2WN9A 4BQTA 1UW6A 3TLUA 5AFJA 2BG9B 2YKSA 3RQWA 2XQ6A 4IREA 4QAAA 4ZRUA 2ZJVA 2XZ5A 3ZDGA 3U8JA 4NPPA 5J5HA 3C79A 4LMJA 4QABA 3TLWA 2BYQA 2W8FA 2XQAA 3UU3A 5AINA 2W8GA 5L4HA 3UUBA 2WZYA 2YOEA 5HEGA 3RI5A 1UV6A 5IUXA 5AFKA 2UZ6A 3UU8A 3RHWA 2YMEA 5HEHA 4HFIA 2WNLA 4AFGA 3JADA 4HFEA 4QH5A 3WTNA 2YMDA 3WTLA 2BG9C 3SH1A 4ZZBA 2BYPA 1UX2A 5TVCA 3TLTA 5HCJA 4ILBA 5L47A 2XYTA 4ALXA 2XQ8A 3PEOA 4FRRA 2PGZA 3TLSA 2X00D 4HFBA 3U8MA 3WTHA 4ZJTA 4AFHA 3EI0A 2BG9E 5AFHA 5HEUA 4QH1A 3UU4A 3JAEA 3PMZA 2BYNA 2XYSA 4UM1A 4ZK4A 4ZR6A 3WTKA 5CFBA 5HEJA 3RIAA 4ILCA 4UM3S 2BR8A 4Z91A 3SIOA 5LG3A 2Y7YA 4UXUA 2BYRA 2BYSA 2C9TA 5HEOA 2ZJUA 3SQ6A 3U8NA 5AFMA 4ZZCA 4TWHA 5FJVA 5J5IA 4DBMA 2XZ6A 2BR7A 4X5TA 5J5FA 4TWDA 4NZBA 2Y57A 5J0ZA 3UU5A 3U8LA 3ZKRA 5LXBA 3LSVA 5KZUA 4LMLA 4B5DA 2X00A 3WTJA 5HCMA 4QH4A 3EHZA 2VL0A 2QC1B 5JMEA 4LMKA 5BRXA 3P50A 4Z90A 5AFMB 4XHEA 2WNJA 5AFLA 2WNCA 4A98A 4HFDA 4ILAA 4AFTA 3TLVA 4BFQA 3WTIA 4D01A 4IL4A 3ZDHA 3RQUA 5BW2A 4WV9A 3UU6A 4TNWA 4EZ1A 4ZJSA 3P4WA 2YN6A 2XNVA 2XNTA 2PH9A 2XQ4A 2Y58A 2Y56A 3SQ9A 4A97A 4COFA 4TWFA 4F8HA 5AFNA 2XQ5A 4HFHA 2BJ0A 4IL9A 3WTMA 4UY2A 4HQPA 3JAFA 2XNUA 5J5GA 3WTOA 3UQ4A 3GUAA 4PIRA 5BP0A 3C84A 5CO5A 3UQ7A 2BG9A 4HFCA 4UM3P
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3T4M A;  3U8K A;  5SYO A;  2XQ9 A;  5L4E A;  3RIF A;  4QAC A;  2XQ3 A;  3IGQ A;  4ZK1 A;  4XK9 A;  5KE4 A;  2XQ7 A;  2Y54 A;  3WIP A;  3EAM A;  4UM3 A;  4TNV A;  1I9B A;  2WN9 A;  4BQT A;  1UW6 A;  3TLU A;  5AFJ A;  2BG9 B;  2YKS A;  3RQW A;  2XQ6 A;  4IRE A;  4QAA A;  4ZRU A;  2ZJV A;  2XZ5 A;  3ZDG A;  3U8J A;  4NPP A;  5J5H A;  3C79 A;  4LMJ A;  4QAB A;  3TLW A;  2BYQ A;  2W8F A;  2XQA A;  3UU3 A;  5AIN A;  2W8G A;  5L4H A;  3UUB A;  2WZY A;  2YOE A;  5HEG A;  3RI5 A;  1UV6 A;  5IUX A;  5AFK A;  2UZ6 A;  3UU8 A;  3RHW A;  2YME A;  5HEH A;  4HFI A;  2WNL A;  4AFG A;  3JAD A;  4HFE A;  4QH5 A;  3WTN A;  2YMD A;  3WTL A;  2BG9 C;  3SH1 A;  4ZZB A;  2BYP A;  1UX2 A;  5TVC A;  3TLT A;  5HCJ A;  4ILB A;  5L47 A;  2XYT A;  4ALX A;  2XQ8 A;  3PEO A;  4FRR A;  2PGZ A;  3TLS A;  2X00 D;  4HFB A;  3U8M A;  3WTH A;  4ZJT A;  4AFH A;  3EI0 A;  2BG9 E;  5AFH A;  5HEU A;  4QH1 A;  3UU4 A;  3JAE A;  3PMZ A;  2BYN A;  2XYS A;  4UM1 A;  4ZK4 A;  4ZR6 A;  3WTK A;  5CFB A;  5HEJ A;  3RIA A;  4ILC A;  4UM3 S;  2BR8 A;  4Z91 A;  3SIO A;  5LG3 A;  2Y7Y A;  4UXU A;  2BYR A;  2BYS A;  2C9T A;  5HEO A;  2ZJU A;  3SQ6 A;  3U8N A;  5AFM A;  4ZZC A;  4TWH A;  5FJV A;  5J5I A;  4DBM A;  2XZ6 A;  2BR7 A;  4X5T A;  5J5F A;  4TWD A;  4NZB A;  2Y57 A;  5J0Z A;  3UU5 A;  3U8L A;  3ZKR A;  5LXB A;  3LSV A;  5KZU A;  4LML A;  4B5D A;  2X00 A;  3WTJ A;  5HCM A;  4QH4 A;  3EHZ A;  2VL0 A;  2QC1 B;  5JME A;  4LMK A;  5BRX A;  3P50 A;  4Z90 A;  5AFM B;  4XHE A;  2WNJ A;  5AFL A;  2WNC A;  4A98 A;  4HFD A;  4ILA A;  4AFT A;  3TLV A;  4BFQ A;  3WTI A;  4D01 A;  4IL4 A;  3ZDH A;  3RQU A;  5BW2 A;  4WV9 A;  3UU6 A;  4TNW A;  4EZ1 A;  4ZJS A;  3P4W A;  2YN6 A;  2XNV A;  2XNT A;  2PH9 A;  2XQ4 A;  2Y58 A;  2Y56 A;  3SQ9 A;  4A97 A;  4COF A;  4TWF A;  4F8H A;  5AFN A;  2XQ5 A;  4HFH A;  2BJ0 A;  4IL9 A;  3WTM A;  4UY2 A;  4HQP A;  3JAF A;  2XNU A;  5J5G A;  3WTO A;  3UQ4 A;  3GUA A;  4PIR A;  5BP0 A;  3C84 A;  5CO5 A;  3UQ7 A;  2BG9 A;  4HFC A;  4UM3 P; 
#chains in the Genus database with same CATH topology
 3T4M A;  3U8K A;  5SYO A;  2XQ9 A;  5L4E A;  3RIF A;  4QAC A;  2XQ3 A;  3IGQ A;  4ZK1 A;  4XK9 A;  5KE4 A;  2XQ7 A;  2Y54 A;  3WIP A;  3EAM A;  4UM3 A;  4TNV A;  1I9B A;  2WN9 A;  4BQT A;  1UW6 A;  3TLU A;  5AFJ A;  2BG9 B;  2YKS A;  3RQW A;  2XQ6 A;  4IRE A;  4QAA A;  4ZRU A;  2ZJV A;  2XZ5 A;  3ZDG A;  3U8J A;  4NPP A;  5J5H A;  3C79 A;  4LMJ A;  4QAB A;  3TLW A;  2BYQ A;  2W8F A;  2XQA A;  3UU3 A;  5AIN A;  2W8G A;  5L4H A;  3UUB A;  2WZY A;  2YOE A;  5HEG A;  3RI5 A;  1UV6 A;  5IUX A;  5AFK A;  2UZ6 A;  3UU8 A;  3RHW A;  2YME A;  5HEH A;  4HFI A;  2WNL A;  4AFG A;  3JAD A;  4HFE A;  4QH5 A;  3WTN A;  2YMD A;  3WTL A;  2BG9 C;  3SH1 A;  4ZZB A;  2BYP A;  1UX2 A;  5TVC A;  3TLT A;  5HCJ A;  4ILB A;  5L47 A;  2XYT A;  4ALX A;  2XQ8 A;  3PEO A;  4FRR A;  2PGZ A;  3TLS A;  2X00 D;  4HFB A;  3U8M A;  3WTH A;  4ZJT A;  4AFH A;  3EI0 A;  2BG9 E;  5AFH A;  5HEU A;  4QH1 A;  3UU4 A;  3JAE A;  3PMZ A;  2BYN A;  2XYS A;  4UM1 A;  4ZK4 A;  4ZR6 A;  3WTK A;  5CFB A;  5HEJ A;  3RIA A;  4ILC A;  4UM3 S;  2BR8 A;  4Z91 A;  3SIO A;  5LG3 A;  2Y7Y A;  4UXU A;  2BYR A;  2BYS A;  2C9T A;  5HEO A;  2ZJU A;  3SQ6 A;  3U8N A;  5AFM A;  4ZZC A;  4TWH A;  5FJV A;  5J5I A;  4DBM A;  2XZ6 A;  2BR7 A;  4X5T A;  5J5F A;  4TWD A;  4NZB A;  2Y57 A;  5J0Z A;  3UU5 A;  3U8L A;  3ZKR A;  5LXB A;  3LSV A;  5KZU A;  4LML A;  4B5D A;  2X00 A;  3WTJ A;  5HCM A;  4QH4 A;  3EHZ A;  2VL0 A;  2QC1 B;  5JME A;  4LMK A;  5BRX A;  3P50 A;  4Z90 A;  5AFM B;  4XHE A;  2WNJ A;  5AFL A;  2WNC A;  4A98 A;  4HFD A;  4ILA A;  4AFT A;  3TLV A;  4BFQ A;  3WTI A;  4D01 A;  4IL4 A;  3ZDH A;  3RQU A;  5BW2 A;  4WV9 A;  3UU6 A;  4TNW A;  4EZ1 A;  4ZJS A;  3P4W A;  2YN6 A;  2XNV A;  2XNT A;  2PH9 A;  2XQ4 A;  2Y58 A;  2Y56 A;  3SQ9 A;  4A97 A;  4COF A;  4TWF A;  4F8H A;  5AFN A;  2XQ5 A;  4HFH A;  2BJ0 A;  4IL9 A;  3WTM A;  4UY2 A;  4HQP A;  3JAF A;  2XNU A;  5J5G A;  3WTO A;  3UQ4 A;  3GUA A;  4PIR A;  5BP0 A;  3C84 A;  5CO5 A;  3UQ7 A;  2BG9 A;  4HFC A;  4UM3 P; 
#chains in the Genus database with same CATH homology
 3T4M A;  3U8K A;  5SYO A;  2XQ9 A;  5L4E A;  3RIF A;  4QAC A;  2XQ3 A;  3IGQ A;  4ZK1 A;  4XK9 A;  5KE4 A;  2XQ7 A;  2Y54 A;  3WIP A;  3EAM A;  4UM3 A;  4TNV A;  1I9B A;  2WN9 A;  4BQT A;  1UW6 A;  3TLU A;  5AFJ A;  2BG9 B;  2YKS A;  3RQW A;  2XQ6 A;  4IRE A;  4QAA A;  4ZRU A;  2ZJV A;  2XZ5 A;  3ZDG A;  3U8J A;  4NPP A;  5J5H A;  3C79 A;  4LMJ A;  4QAB A;  3TLW A;  2BYQ A;  2W8F A;  2XQA A;  3UU3 A;  5AIN A;  2W8G A;  5L4H A;  3UUB A;  2WZY A;  2YOE A;  5HEG A;  3RI5 A;  1UV6 A;  5IUX A;  5AFK A;  2UZ6 A;  3UU8 A;  3RHW A;  2YME A;  5HEH A;  4HFI A;  2WNL A;  4AFG A;  3JAD A;  4HFE A;  4QH5 A;  3WTN A;  2YMD A;  3WTL A;  2BG9 C;  3SH1 A;  4ZZB A;  2BYP A;  1UX2 A;  5TVC A;  3TLT A;  5HCJ A;  4ILB A;  5L47 A;  2XYT A;  4ALX A;  2XQ8 A;  3PEO A;  4FRR A;  2PGZ A;  3TLS A;  2X00 D;  4HFB A;  3U8M A;  3WTH A;  4ZJT A;  4AFH A;  3EI0 A;  2BG9 E;  5AFH A;  5HEU A;  4QH1 A;  3UU4 A;  3JAE A;  3PMZ A;  2BYN A;  2XYS A;  4UM1 A;  4ZK4 A;  4ZR6 A;  3WTK A;  5CFB A;  5HEJ A;  3RIA A;  4ILC A;  4UM3 S;  2BR8 A;  4Z91 A;  3SIO A;  5LG3 A;  2Y7Y A;  4UXU A;  2BYR A;  2BYS A;  2C9T A;  5HEO A;  2ZJU A;  3SQ6 A;  3U8N A;  5AFM A;  4ZZC A;  4TWH A;  5FJV A;  5J5I A;  4DBM A;  2XZ6 A;  2BR7 A;  4X5T A;  5J5F A;  4TWD A;  4NZB A;  2Y57 A;  5J0Z A;  3UU5 A;  3U8L A;  3ZKR A;  5LXB A;  3LSV A;  5KZU A;  4LML A;  4B5D A;  2X00 A;  3WTJ A;  5HCM A;  4QH4 A;  3EHZ A;  2VL0 A;  2QC1 B;  5JME A;  4LMK A;  5BRX A;  3P50 A;  4Z90 A;  5AFM B;  4XHE A;  2WNJ A;  5AFL A;  2WNC A;  4A98 A;  4HFD A;  4ILA A;  4AFT A;  3TLV A;  4BFQ A;  3WTI A;  4D01 A;  4IL4 A;  3ZDH A;  3RQU A;  5BW2 A;  4WV9 A;  3UU6 A;  4TNW A;  4EZ1 A;  4ZJS A;  3P4W A;  2YN6 A;  2XNV A;  2XNT A;  2PH9 A;  2XQ4 A;  2Y58 A;  2Y56 A;  3SQ9 A;  4A97 A;  4COF A;  4TWF A;  4F8H A;  5AFN A;  2XQ5 A;  4HFH A;  2BJ0 A;  4IL9 A;  3WTM A;  4UY2 A;  4HQP A;  3JAF A;  2XNU A;  5J5G A;  3WTO A;  3UQ4 A;  3GUA A;  4PIR A;  5BP0 A;  3C84 A;  5CO5 A;  3UQ7 A;  2BG9 A;  4HFC A;  4UM3 P; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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