2X00 | Genus

Total Genus 54

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	54
sequence length	212
structure length	212
Chain Sequence	DDDLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Receptor
source organism	Aplysia californica
publication title	Structural Determinants in Phycotoxins and Achbp Conferring High Affinity Binding and Nicotinic Achr Antagonism. pubmed doi rcsb
molecule keywords	SOLUBLE ACETYLCHOLINE RECEPTOR
total genus	54
structure length	212
sequence length	212
ec nomenclature
pdb deposition date	2009-12-04

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
D	PF02931	Neur_chan_LBD	Neurotransmitter-gated ion-channel ligand binding domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.70.170.10	Mainly Beta	Distorted Sandwich	Acetylcholine Binding Protein; Chain: A,	Neurotransmitter-gated ion-channel ligand-binding domain	2x00D00

4ZRUA 2W8GA 3WIPA 3U8NA 4ZJTA 3WTOA 4TNWA 5HEGA 3WTHA 5HEUA 2BG9A 4B5DA 4AFHA 5L4EA 2XQ6A 4X5TA 2BYNA 2BG9B 2XZ6A 2BYPA 2YOEA 2C9TA 5FJVA 2BG9E 2X00D 2PGZA 2XQ9A 3U8KA 3UU3A 1I9BA 4HFBA 3JAEA 3RQUA 4TWHA 4QAAA 3U8MA 3C84A 2BG9C 5AFJA 3SQ9A 5AFLA 3TLUA 4ZR6A 4LMJA 3RIAA 1UX2A 4IL9A 4QACA 4UXUA 4XHEA 2PH9A 3U8LA 3UQ7A 5BP0A 3RIFA 3TLWA 3TLVA 4QH1A 3JADA 4IREA 4TWDA 2XQAA 4ALXA 5HCMA 3EHZA 4DBMA 4UM1A 3WTJA 2Y57A 4AFGA 3WTIA 3UU4A 3TLTA 2YN6A 4Z90A 2XZ5A 2ZJUA 4TNVA 3RI5A 5BRXA 2XQ7A 4QH5A 4BFQA 5J5HA 4HFCA 3SH1A 4NZBA 3WTMA 3RQWA 4UM3A 5BW2A 4ZZCA 2QC1B 4UY2A 4D01A 5CFBA 4PIRA 3UU5A 2BR8A 2UZ6A 4HFEA 4ZJSA 4QH4A 5J5IA 4ILBA 1UV6A 5KZUA 3ZDHA 3EAMA 5L47A 4UM3P 2VL0A 4FRRA 2Y7YA 5HEOA 3U8JA 5JMEA 2BYRA 3PMZA 3TLSA 3ZDGA 5LG3A 3T4MA 3UU8A 2BYSA 5TVCA 3SQ6A 2XQ5A 3GUAA 2XQ4A 4LMKA 2ZJVA 3WTKA 3EI0A 2XQ8A 5J5GA 2XNTA 4A97A 2XQ3A 2BYQA 5L4HA 3RHWA 2YMDA 2YMEA 4NPPA 4QABA 5CO5A 4COFA 4ZK1A 2WNJA 2WNLA 5J5FA 3P50A 5LXBA 3PEOA 4ILAA 2YKSA 2XYTA 2XNVA 4F8HA 4ZZBA 4EZ1A 5KE4A 4WV9A 2Y58A 3UU6A 4Z91A 4AFTA 4BQTA 3UUBA 3WTLA 5HCJA 5AFNA 5AFKA 3P4WA 3UQ4A 3ZKRA 5AFHA 1UW6A 3IGQA 4HFDA 4HFIA 3C79A 4IL4A 3JAFA 3WTNA 2X00A 4ZK4A 2Y54A 4A98A 2BJ0A 5SYOA 2BR7A 5J0ZA 4LMLA 5HEHA 2WN9A 2Y56A 5AINA 2WNCA 4HFHA 4ILCA 4UM3S 5AFMA 5IUXA 2XNUA 2WZYA 3LSVA 4HQPA 2XYSA 3SIOA 5HEJA 2W8FA 4XK9A 4TWFA 5AFMB
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 4ZRU A;  2W8G A;  3WIP A;  3U8N A;  4ZJT A;  3WTO A;  4TNW A;  5HEG A;  3WTH A;  5HEU A;  2BG9 A;  4B5D A;  4AFH A;  5L4E A;  2XQ6 A;  4X5T A;  2BYN A;  2BG9 B;  2XZ6 A;  2BYP A;  2YOE A;  2C9T A;  5FJV A;  2BG9 E;  2X00 D;  2PGZ A;  2XQ9 A;  3U8K A;  3UU3 A;  1I9B A;  4HFB A;  3JAE A;  3RQU A;  4TWH A;  4QAA A;  3U8M A;  3C84 A;  2BG9 C;  5AFJ A;  3SQ9 A;  5AFL A;  3TLU A;  4ZR6 A;  4LMJ A;  3RIA A;  1UX2 A;  4IL9 A;  4QAC A;  4UXU A;  4XHE A;  2PH9 A;  3U8L A;  3UQ7 A;  5BP0 A;  3RIF A;  3TLW A;  3TLV A;  4QH1 A;  3JAD A;  4IRE A;  4TWD A;  2XQA A;  4ALX A;  5HCM A;  3EHZ A;  4DBM A;  4UM1 A;  3WTJ A;  2Y57 A;  4AFG A;  3WTI A;  3UU4 A;  3TLT A;  2YN6 A;  4Z90 A;  2XZ5 A;  2ZJU A;  4TNV A;  3RI5 A;  5BRX A;  2XQ7 A;  4QH5 A;  4BFQ A;  5J5H A;  4HFC A;  3SH1 A;  4NZB A;  3WTM A;  3RQW A;  4UM3 A;  5BW2 A;  4ZZC A;  2QC1 B;  4UY2 A;  4D01 A;  5CFB A;  4PIR A;  3UU5 A;  2BR8 A;  2UZ6 A;  4HFE A;  4ZJS A;  4QH4 A;  5J5I A;  4ILB A;  1UV6 A;  5KZU A;  3ZDH A;  3EAM A;  5L47 A;  4UM3 P;  2VL0 A;  4FRR A;  2Y7Y A;  5HEO A;  3U8J A;  5JME A;  2BYR A;  3PMZ A;  3TLS A;  3ZDG A;  5LG3 A;  3T4M A;  3UU8 A;  2BYS A;  5TVC A;  3SQ6 A;  2XQ5 A;  3GUA A;  2XQ4 A;  4LMK A;  2ZJV A;  3WTK A;  3EI0 A;  2XQ8 A;  5J5G A;  2XNT A;  4A97 A;  2XQ3 A;  2BYQ A;  5L4H A;  3RHW A;  2YMD A;  2YME A;  4NPP A;  4QAB A;  5CO5 A;  4COF A;  4ZK1 A;  2WNJ A;  2WNL A;  5J5F A;  3P50 A;  5LXB A;  3PEO A;  4ILA A;  2YKS A;  2XYT A;  2XNV A;  4F8H A;  4ZZB A;  4EZ1 A;  5KE4 A;  4WV9 A;  2Y58 A;  3UU6 A;  4Z91 A;  4AFT A;  4BQT A;  3UUB A;  3WTL A;  5HCJ A;  5AFN A;  5AFK A;  3P4W A;  3UQ4 A;  3ZKR A;  5AFH A;  1UW6 A;  3IGQ A;  4HFD A;  4HFI A;  3C79 A;  4IL4 A;  3JAF A;  3WTN A;  2X00 A;  4ZK4 A;  2Y54 A;  4A98 A;  2BJ0 A;  5SYO A;  2BR7 A;  5J0Z A;  4LML A;  5HEH A;  2WN9 A;  2Y56 A;  5AIN A;  2WNC A;  4HFH A;  4ILC A;  4UM3 S;  5AFM A;  5IUX A;  2XNU A;  2WZY A;  3LSV A;  4HQP A;  2XYS A;  3SIO A;  5HEJ A;  2W8F A;  4XK9 A;  4TWF A;  5AFM B; 
#chains in the Genus database with same CATH topology
 4ZRU A;  2W8G A;  3WIP A;  3U8N A;  4ZJT A;  3WTO A;  4TNW A;  5HEG A;  3WTH A;  5HEU A;  2BG9 A;  4B5D A;  4AFH A;  5L4E A;  2XQ6 A;  4X5T A;  2BYN A;  2BG9 B;  2XZ6 A;  2BYP A;  2YOE A;  2C9T A;  5FJV A;  2BG9 E;  2X00 D;  2PGZ A;  2XQ9 A;  3U8K A;  3UU3 A;  1I9B A;  4HFB A;  3JAE A;  3RQU A;  4TWH A;  4QAA A;  3U8M A;  3C84 A;  2BG9 C;  5AFJ A;  3SQ9 A;  5AFL A;  3TLU A;  4ZR6 A;  4LMJ A;  3RIA A;  1UX2 A;  4IL9 A;  4QAC A;  4UXU A;  4XHE A;  2PH9 A;  3U8L A;  3UQ7 A;  5BP0 A;  3RIF A;  3TLW A;  3TLV A;  4QH1 A;  3JAD A;  4IRE A;  4TWD A;  2XQA A;  4ALX A;  5HCM A;  3EHZ A;  4DBM A;  4UM1 A;  3WTJ A;  2Y57 A;  4AFG A;  3WTI A;  3UU4 A;  3TLT A;  2YN6 A;  4Z90 A;  2XZ5 A;  2ZJU A;  4TNV A;  3RI5 A;  5BRX A;  2XQ7 A;  4QH5 A;  4BFQ A;  5J5H A;  4HFC A;  3SH1 A;  4NZB A;  3WTM A;  3RQW A;  4UM3 A;  5BW2 A;  4ZZC A;  2QC1 B;  4UY2 A;  4D01 A;  5CFB A;  4PIR A;  3UU5 A;  2BR8 A;  2UZ6 A;  4HFE A;  4ZJS A;  4QH4 A;  5J5I A;  4ILB A;  1UV6 A;  5KZU A;  3ZDH A;  3EAM A;  5L47 A;  4UM3 P;  2VL0 A;  4FRR A;  2Y7Y A;  5HEO A;  3U8J A;  5JME A;  2BYR A;  3PMZ A;  3TLS A;  3ZDG A;  5LG3 A;  3T4M A;  3UU8 A;  2BYS A;  5TVC A;  3SQ6 A;  2XQ5 A;  3GUA A;  2XQ4 A;  4LMK A;  2ZJV A;  3WTK A;  3EI0 A;  2XQ8 A;  5J5G A;  2XNT A;  4A97 A;  2XQ3 A;  2BYQ A;  5L4H A;  3RHW A;  2YMD A;  2YME A;  4NPP A;  4QAB A;  5CO5 A;  4COF A;  4ZK1 A;  2WNJ A;  2WNL A;  5J5F A;  3P50 A;  5LXB A;  3PEO A;  4ILA A;  2YKS A;  2XYT A;  2XNV A;  4F8H A;  4ZZB A;  4EZ1 A;  5KE4 A;  4WV9 A;  2Y58 A;  3UU6 A;  4Z91 A;  4AFT A;  4BQT A;  3UUB A;  3WTL A;  5HCJ A;  5AFN A;  5AFK A;  3P4W A;  3UQ4 A;  3ZKR A;  5AFH A;  1UW6 A;  3IGQ A;  4HFD A;  4HFI A;  3C79 A;  4IL4 A;  3JAF A;  3WTN A;  2X00 A;  4ZK4 A;  2Y54 A;  4A98 A;  2BJ0 A;  5SYO A;  2BR7 A;  5J0Z A;  4LML A;  5HEH A;  2WN9 A;  2Y56 A;  5AIN A;  2WNC A;  4HFH A;  4ILC A;  4UM3 S;  5AFM A;  5IUX A;  2XNU A;  2WZY A;  3LSV A;  4HQP A;  2XYS A;  3SIO A;  5HEJ A;  2W8F A;  4XK9 A;  4TWF A;  5AFM B; 
#chains in the Genus database with same CATH homology
 4ZRU A;  2W8G A;  3WIP A;  3U8N A;  4ZJT A;  3WTO A;  4TNW A;  5HEG A;  3WTH A;  5HEU A;  2BG9 A;  4B5D A;  4AFH A;  5L4E A;  2XQ6 A;  4X5T A;  2BYN A;  2BG9 B;  2XZ6 A;  2BYP A;  2YOE A;  2C9T A;  5FJV A;  2BG9 E;  2X00 D;  2PGZ A;  2XQ9 A;  3U8K A;  3UU3 A;  1I9B A;  4HFB A;  3JAE A;  3RQU A;  4TWH A;  4QAA A;  3U8M A;  3C84 A;  2BG9 C;  5AFJ A;  3SQ9 A;  5AFL A;  3TLU A;  4ZR6 A;  4LMJ A;  3RIA A;  1UX2 A;  4IL9 A;  4QAC A;  4UXU A;  4XHE A;  2PH9 A;  3U8L A;  3UQ7 A;  5BP0 A;  3RIF A;  3TLW A;  3TLV A;  4QH1 A;  3JAD A;  4IRE A;  4TWD A;  2XQA A;  4ALX A;  5HCM A;  3EHZ A;  4DBM A;  4UM1 A;  3WTJ A;  2Y57 A;  4AFG A;  3WTI A;  3UU4 A;  3TLT A;  2YN6 A;  4Z90 A;  2XZ5 A;  2ZJU A;  4TNV A;  3RI5 A;  5BRX A;  2XQ7 A;  4QH5 A;  4BFQ A;  5J5H A;  4HFC A;  3SH1 A;  4NZB A;  3WTM A;  3RQW A;  4UM3 A;  5BW2 A;  4ZZC A;  2QC1 B;  4UY2 A;  4D01 A;  5CFB A;  4PIR A;  3UU5 A;  2BR8 A;  2UZ6 A;  4HFE A;  4ZJS A;  4QH4 A;  5J5I A;  4ILB A;  1UV6 A;  5KZU A;  3ZDH A;  3EAM A;  5L47 A;  4UM3 P;  2VL0 A;  4FRR A;  2Y7Y A;  5HEO A;  3U8J A;  5JME A;  2BYR A;  3PMZ A;  3TLS A;  3ZDG A;  5LG3 A;  3T4M A;  3UU8 A;  2BYS A;  5TVC A;  3SQ6 A;  2XQ5 A;  3GUA A;  2XQ4 A;  4LMK A;  2ZJV A;  3WTK A;  3EI0 A;  2XQ8 A;  5J5G A;  2XNT A;  4A97 A;  2XQ3 A;  2BYQ A;  5L4H A;  3RHW A;  2YMD A;  2YME A;  4NPP A;  4QAB A;  5CO5 A;  4COF A;  4ZK1 A;  2WNJ A;  2WNL A;  5J5F A;  3P50 A;  5LXB A;  3PEO A;  4ILA A;  2YKS A;  2XYT A;  2XNV A;  4F8H A;  4ZZB A;  4EZ1 A;  5KE4 A;  4WV9 A;  2Y58 A;  3UU6 A;  4Z91 A;  4AFT A;  4BQT A;  3UUB A;  3WTL A;  5HCJ A;  5AFN A;  5AFK A;  3P4W A;  3UQ4 A;  3ZKR A;  5AFH A;  1UW6 A;  3IGQ A;  4HFD A;  4HFI A;  3C79 A;  4IL4 A;  3JAF A;  3WTN A;  2X00 A;  4ZK4 A;  2Y54 A;  4A98 A;  2BJ0 A;  5SYO A;  2BR7 A;  5J0Z A;  4LML A;  5HEH A;  2WN9 A;  2Y56 A;  5AIN A;  2WNC A;  4HFH A;  4ILC A;  4UM3 S;  5AFM A;  5IUX A;  2XNU A;  2WZY A;  3LSV A;  4HQP A;  2XYS A;  3SIO A;  5HEJ A;  2W8F A;  4XK9 A;  4TWF A;  5AFM B;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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2X00D

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations