2X00D

Crystal structure of a-achbp in complex with gymnodimine a
Total Genus 54
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
212
structure length
212
Chain Sequence
DDDLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural Determinants in Phycotoxins and Achbp Conferring High Affinity Binding and Nicotinic Achr Antagonism.
pubmed doi rcsb
molecule tags Receptor
source organism Aplysia californica
molecule keywords SOLUBLE ACETYLCHOLINE RECEPTOR
total genus 54
structure length 212
sequence length 212
ec nomenclature
pdb deposition date 2009-12-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 2x00D00
2YKSA 1UX2A 3JADA 4HFCA 3TLWA 5L4EA 3UQ4A 2XZ6A 4UXUA 2BYRA 3RIFA 3TLUA 5HEUA 3GUAA 2WNCA 4WV9A 3EHZA 4BQTA 2XQ5A 4ZK4A 5AFMA 3RQUA 3P50A 4AFTA 4AFGA 2XYTA 4AFHA 5AFLA 2XZ5A 5J5HA 2WN9A 5AFJA 2ZJUA 2XYSA 3SQ6A 3U8JA 4UM1A 4ZK1A 5AFHA 4ILCA 5HCJA 2BJ0A 4F8HA 2Y56A 4HFIA 2Y54A 4LMKA 3JAFA 2W8FA 5HCMA 3WTNA 2WNLA 2XQ7A 5HEGA 3RHWA 3UU5A 2XQ9A 3WTHA 5CO5A 2ZJVA 2WZYA 4XK9A 5AFKA 1UV6A 3UU3A 2PGZA 4HFDA 5BRXA 3PEOA 2Y57A 2BR7A 4COFA 5AFMB 1I9BA 5FJVA 3ZDHA 4LMLA 3T4MA 4A97A 5AFNA 2BYNA 3U8LA 3UUBA 3RIAA 5SYOA 4Z91A 4ZJSA 3LSVA 3UU6A 2XNUA 4XHEA 2BYSA 5KZUA 2BG9C 3WTMA 2XNVA 4HQPA 3WTLA 2VL0A 3ZDGA 4HFBA 4FRRA 4TWFA 4B5DA 3WIPA 5LXBA 2Y58A 3P4WA 5LG3A 4ZR6A 4ZJTA 3WTIA 2W8GA 3PMZA 5TVCA 2BYQA 3RQWA 3U8KA 3EI0A 2XQ8A 3SIOA 4HFHA 3WTKA 4IL4A 5KE4A 2XNTA 4ZZBA 3UQ7A 2YMDA 5CFBA 3ZKRA 2BG9E 3SQ9A 2X00A 4D01A 4UM3A 4UM3S 2UZ6A 4PIRA 4QAAA 3U8MA 2YOEA 5L47A 3EAMA 4IREA 3JAEA 5HEHA 3C79A 2BG9A 3TLSA 5J5IA 4BFQA 4NZBA 2BR8A 4QACA 3RI5A 2Y7YA 4QH5A 4QH1A 5J5GA 5L4HA 4TWDA 4IL9A 4X5TA 4TNWA 2C9TA 3IGQA 4UY2A 2XQAA 3TLVA 3UU8A 4HFEA 2YMEA 4A98A 3TLTA 5IUXA 3U8NA 5J0ZA 5HEOA 4QH4A 3WTJA 2X00D 3UU4A 2QC1B 4TNVA 4DBMA 5BW2A 2XQ4A 4ALXA 3C84A 4Z90A 4ZZCA 2BG9B 4UM3P 2YN6A 4QABA 5BP0A 2XQ6A 4LMJA 5HEJA 5J5FA 2BYPA 2PH9A 4ILAA 4ZRUA 5JMEA 1UW6A 4EZ1A 3WTOA 4TWHA 5AINA 3SH1A 4NPPA 2WNJA 4ILBA 2XQ3A
chains in the Genus database with same CATH superfamily
2YKSA 1UX2A 3JADA 4HFCA 3TLWA 5L4EA 3UQ4A 2XZ6A 4UXUA 2BYRA 3RIFA 3TLUA 5HEUA 3GUAA 2WNCA 4WV9A 3EHZA 4BQTA 2XQ5A 4ZK4A 5AFMA 3RQUA 3P50A 4AFTA 4AFGA 2XYTA 4AFHA 5AFLA 2XZ5A 5J5HA 2WN9A 5AFJA 2ZJUA 2XYSA 3SQ6A 3U8JA 4UM1A 4ZK1A 5AFHA 4ILCA 5HCJA 2BJ0A 4F8HA 2Y56A 4HFIA 2Y54A 4LMKA 3JAFA 2W8FA 5HCMA 3WTNA 2WNLA 2XQ7A 5HEGA 3RHWA 3UU5A 2XQ9A 3WTHA 5CO5A 2ZJVA 2WZYA 4XK9A 5AFKA 1UV6A 3UU3A 2PGZA 4HFDA 5BRXA 3PEOA 2Y57A 2BR7A 4COFA 5AFMB 1I9BA 5FJVA 3ZDHA 4LMLA 3T4MA 4A97A 5AFNA 2BYNA 3U8LA 3UUBA 3RIAA 5SYOA 4Z91A 4ZJSA 3LSVA 3UU6A 2XNUA 4XHEA 2BYSA 5KZUA 2BG9C 3WTMA 2XNVA 4HQPA 3WTLA 2VL0A 3ZDGA 4HFBA 4FRRA 4TWFA 4B5DA 3WIPA 5LXBA 2Y58A 3P4WA 5LG3A 4ZR6A 4ZJTA 3WTIA 2W8GA 3PMZA 5TVCA 2BYQA 3RQWA 3U8KA 3EI0A 2XQ8A 3SIOA 4HFHA 3WTKA 4IL4A 5KE4A 2XNTA 4ZZBA 3UQ7A 2YMDA 5CFBA 3ZKRA 2BG9E 3SQ9A 2X00A 4D01A 4UM3A 4UM3S 2UZ6A 4PIRA 4QAAA 3U8MA 2YOEA 5L47A 3EAMA 4IREA 3JAEA 5HEHA 3C79A 2BG9A 3TLSA 5J5IA 4BFQA 4NZBA 2BR8A 4QACA 3RI5A 2Y7YA 4QH5A 4QH1A 5J5GA 5L4HA 4TWDA 4IL9A 4X5TA 4TNWA 2C9TA 3IGQA 4UY2A 2XQAA 3TLVA 3UU8A 4HFEA 2YMEA 4A98A 3TLTA 5IUXA 3U8NA 5J0ZA 5HEOA 4QH4A 3WTJA 2X00D 3UU4A 2QC1B 4TNVA 4DBMA 5BW2A 2XQ4A 4ALXA 3C84A 4Z90A 4ZZCA 2BG9B 4UM3P 2YN6A 4QABA 5BP0A 2XQ6A 4LMJA 5HEJA 5J5FA 2BYPA 2PH9A 4ILAA 4ZRUA 5JMEA 1UW6A 4EZ1A 3WTOA 4TWHA 5AINA 3SH1A 4NPPA 2WNJA 4ILBA 2XQ3A
chains in the Genus database with same CATH topology
2YKSA 1UX2A 3JADA 4HFCA 3TLWA 5L4EA 3UQ4A 2XZ6A 4UXUA 2BYRA 3RIFA 3TLUA 5HEUA 3GUAA 2WNCA 4WV9A 3EHZA 4BQTA 2XQ5A 4ZK4A 5AFMA 3RQUA 3P50A 4AFTA 4AFGA 2XYTA 4AFHA 5AFLA 2XZ5A 5J5HA 2WN9A 5AFJA 2ZJUA 2XYSA 3SQ6A 3U8JA 4UM1A 4ZK1A 5AFHA 4ILCA 5HCJA 2BJ0A 4F8HA 2Y56A 4HFIA 2Y54A 4LMKA 3JAFA 2W8FA 5HCMA 3WTNA 2WNLA 2XQ7A 5HEGA 3RHWA 3UU5A 2XQ9A 3WTHA 5CO5A 2ZJVA 2WZYA 4XK9A 5AFKA 1UV6A 3UU3A 2PGZA 4HFDA 5BRXA 3PEOA 2Y57A 2BR7A 4COFA 5AFMB 1I9BA 5FJVA 3ZDHA 4LMLA 3T4MA 4A97A 5AFNA 2BYNA 3U8LA 3UUBA 3RIAA 5SYOA 4Z91A 4ZJSA 3LSVA 3UU6A 2XNUA 4XHEA 2BYSA 5KZUA 2BG9C 3WTMA 2XNVA 4HQPA 3WTLA 2VL0A 3ZDGA 4HFBA 4FRRA 4TWFA 4B5DA 3WIPA 5LXBA 2Y58A 3P4WA 5LG3A 4ZR6A 4ZJTA 3WTIA 2W8GA 3PMZA 5TVCA 2BYQA 3RQWA 3U8KA 3EI0A 2XQ8A 3SIOA 4HFHA 3WTKA 4IL4A 5KE4A 2XNTA 4ZZBA 3UQ7A 2YMDA 5CFBA 3ZKRA 2BG9E 3SQ9A 2X00A 4D01A 4UM3A 4UM3S 2UZ6A 4PIRA 4QAAA 3U8MA 2YOEA 5L47A 3EAMA 4IREA 3JAEA 5HEHA 3C79A 2BG9A 3TLSA 5J5IA 4BFQA 4NZBA 2BR8A 4QACA 3RI5A 2Y7YA 4QH5A 4QH1A 5J5GA 5L4HA 4TWDA 4IL9A 4X5TA 4TNWA 2C9TA 3IGQA 4UY2A 2XQAA 3TLVA 3UU8A 4HFEA 2YMEA 4A98A 3TLTA 5IUXA 3U8NA 5J0ZA 5HEOA 4QH4A 3WTJA 2X00D 3UU4A 2QC1B 4TNVA 4DBMA 5BW2A 2XQ4A 4ALXA 3C84A 4Z90A 4ZZCA 2BG9B 4UM3P 2YN6A 4QABA 5BP0A 2XQ6A 4LMJA 5HEJA 5J5FA 2BYPA 2PH9A 4ILAA 4ZRUA 5JMEA 1UW6A 4EZ1A 3WTOA 4TWHA 5AINA 3SH1A 4NPPA 2WNJA 4ILBA 2XQ3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YKS A;  1UX2 A;  3JAD A;  4HFC A;  3TLW A;  5L4E A;  3UQ4 A;  2XZ6 A;  4UXU A;  2BYR A;  3RIF A;  3TLU A;  5HEU A;  3GUA A;  2WNC A;  4WV9 A;  3EHZ A;  4BQT A;  2XQ5 A;  4ZK4 A;  5AFM A;  3RQU A;  3P50 A;  4AFT A;  4AFG A;  2XYT A;  4AFH A;  5AFL A;  2XZ5 A;  5J5H A;  2WN9 A;  5AFJ A;  2ZJU A;  2XYS A;  3SQ6 A;  3U8J A;  4UM1 A;  4ZK1 A;  5AFH A;  4ILC A;  5HCJ A;  2BJ0 A;  4F8H A;  2Y56 A;  4HFI A;  2Y54 A;  4LMK A;  3JAF A;  2W8F A;  5HCM A;  3WTN A;  2WNL A;  2XQ7 A;  5HEG A;  3RHW A;  3UU5 A;  2XQ9 A;  3WTH A;  5CO5 A;  2ZJV A;  2WZY A;  4XK9 A;  5AFK A;  1UV6 A;  3UU3 A;  2PGZ A;  4HFD A;  5BRX A;  3PEO A;  2Y57 A;  2BR7 A;  4COF A;  5AFM B;  1I9B A;  5FJV A;  3ZDH A;  4LML A;  3T4M A;  4A97 A;  5AFN A;  2BYN A;  3U8L A;  3UUB A;  3RIA A;  5SYO A;  4Z91 A;  4ZJS A;  3LSV A;  3UU6 A;  2XNU A;  4XHE A;  2BYS A;  5KZU A;  2BG9 C;  3WTM A;  2XNV A;  4HQP A;  3WTL A;  2VL0 A;  3ZDG A;  4HFB A;  4FRR A;  4TWF A;  4B5D A;  3WIP A;  5LXB A;  2Y58 A;  3P4W A;  5LG3 A;  4ZR6 A;  4ZJT A;  3WTI A;  2W8G A;  3PMZ A;  5TVC A;  2BYQ A;  3RQW A;  3U8K A;  3EI0 A;  2XQ8 A;  3SIO A;  4HFH A;  3WTK A;  4IL4 A;  5KE4 A;  2XNT A;  4ZZB A;  3UQ7 A;  2YMD A;  5CFB A;  3ZKR A;  2BG9 E;  3SQ9 A;  2X00 A;  4D01 A;  4UM3 A;  4UM3 S;  2UZ6 A;  4PIR A;  4QAA A;  3U8M A;  2YOE A;  5L47 A;  3EAM A;  4IRE A;  3JAE A;  5HEH A;  3C79 A;  2BG9 A;  3TLS A;  5J5I A;  4BFQ A;  4NZB A;  2BR8 A;  4QAC A;  3RI5 A;  2Y7Y A;  4QH5 A;  4QH1 A;  5J5G A;  5L4H A;  4TWD A;  4IL9 A;  4X5T A;  4TNW A;  2C9T A;  3IGQ A;  4UY2 A;  2XQA A;  3TLV A;  3UU8 A;  4HFE A;  2YME A;  4A98 A;  3TLT A;  5IUX A;  3U8N A;  5J0Z A;  5HEO A;  4QH4 A;  3WTJ A;  2X00 D;  3UU4 A;  2QC1 B;  4TNV A;  4DBM A;  5BW2 A;  2XQ4 A;  4ALX A;  3C84 A;  4Z90 A;  4ZZC A;  2BG9 B;  4UM3 P;  2YN6 A;  4QAB A;  5BP0 A;  2XQ6 A;  4LMJ A;  5HEJ A;  5J5F A;  2BYP A;  2PH9 A;  4ILA A;  4ZRU A;  5JME A;  1UW6 A;  4EZ1 A;  3WTO A;  4TWH A;  5AIN A;  3SH1 A;  4NPP A;  2WNJ A;  4ILB A;  2XQ3 A; 
#chains in the Genus database with same CATH topology
 2YKS A;  1UX2 A;  3JAD A;  4HFC A;  3TLW A;  5L4E A;  3UQ4 A;  2XZ6 A;  4UXU A;  2BYR A;  3RIF A;  3TLU A;  5HEU A;  3GUA A;  2WNC A;  4WV9 A;  3EHZ A;  4BQT A;  2XQ5 A;  4ZK4 A;  5AFM A;  3RQU A;  3P50 A;  4AFT A;  4AFG A;  2XYT A;  4AFH A;  5AFL A;  2XZ5 A;  5J5H A;  2WN9 A;  5AFJ A;  2ZJU A;  2XYS A;  3SQ6 A;  3U8J A;  4UM1 A;  4ZK1 A;  5AFH A;  4ILC A;  5HCJ A;  2BJ0 A;  4F8H A;  2Y56 A;  4HFI A;  2Y54 A;  4LMK A;  3JAF A;  2W8F A;  5HCM A;  3WTN A;  2WNL A;  2XQ7 A;  5HEG A;  3RHW A;  3UU5 A;  2XQ9 A;  3WTH A;  5CO5 A;  2ZJV A;  2WZY A;  4XK9 A;  5AFK A;  1UV6 A;  3UU3 A;  2PGZ A;  4HFD A;  5BRX A;  3PEO A;  2Y57 A;  2BR7 A;  4COF A;  5AFM B;  1I9B A;  5FJV A;  3ZDH A;  4LML A;  3T4M A;  4A97 A;  5AFN A;  2BYN A;  3U8L A;  3UUB A;  3RIA A;  5SYO A;  4Z91 A;  4ZJS A;  3LSV A;  3UU6 A;  2XNU A;  4XHE A;  2BYS A;  5KZU A;  2BG9 C;  3WTM A;  2XNV A;  4HQP A;  3WTL A;  2VL0 A;  3ZDG A;  4HFB A;  4FRR A;  4TWF A;  4B5D A;  3WIP A;  5LXB A;  2Y58 A;  3P4W A;  5LG3 A;  4ZR6 A;  4ZJT A;  3WTI A;  2W8G A;  3PMZ A;  5TVC A;  2BYQ A;  3RQW A;  3U8K A;  3EI0 A;  2XQ8 A;  3SIO A;  4HFH A;  3WTK A;  4IL4 A;  5KE4 A;  2XNT A;  4ZZB A;  3UQ7 A;  2YMD A;  5CFB A;  3ZKR A;  2BG9 E;  3SQ9 A;  2X00 A;  4D01 A;  4UM3 A;  4UM3 S;  2UZ6 A;  4PIR A;  4QAA A;  3U8M A;  2YOE A;  5L47 A;  3EAM A;  4IRE A;  3JAE A;  5HEH A;  3C79 A;  2BG9 A;  3TLS A;  5J5I A;  4BFQ A;  4NZB A;  2BR8 A;  4QAC A;  3RI5 A;  2Y7Y A;  4QH5 A;  4QH1 A;  5J5G A;  5L4H A;  4TWD A;  4IL9 A;  4X5T A;  4TNW A;  2C9T A;  3IGQ A;  4UY2 A;  2XQA A;  3TLV A;  3UU8 A;  4HFE A;  2YME A;  4A98 A;  3TLT A;  5IUX A;  3U8N A;  5J0Z A;  5HEO A;  4QH4 A;  3WTJ A;  2X00 D;  3UU4 A;  2QC1 B;  4TNV A;  4DBM A;  5BW2 A;  2XQ4 A;  4ALX A;  3C84 A;  4Z90 A;  4ZZC A;  2BG9 B;  4UM3 P;  2YN6 A;  4QAB A;  5BP0 A;  2XQ6 A;  4LMJ A;  5HEJ A;  5J5F A;  2BYP A;  2PH9 A;  4ILA A;  4ZRU A;  5JME A;  1UW6 A;  4EZ1 A;  3WTO A;  4TWH A;  5AIN A;  3SH1 A;  4NPP A;  2WNJ A;  4ILB A;  2XQ3 A; 
#chains in the Genus database with same CATH homology
 2YKS A;  1UX2 A;  3JAD A;  4HFC A;  3TLW A;  5L4E A;  3UQ4 A;  2XZ6 A;  4UXU A;  2BYR A;  3RIF A;  3TLU A;  5HEU A;  3GUA A;  2WNC A;  4WV9 A;  3EHZ A;  4BQT A;  2XQ5 A;  4ZK4 A;  5AFM A;  3RQU A;  3P50 A;  4AFT A;  4AFG A;  2XYT A;  4AFH A;  5AFL A;  2XZ5 A;  5J5H A;  2WN9 A;  5AFJ A;  2ZJU A;  2XYS A;  3SQ6 A;  3U8J A;  4UM1 A;  4ZK1 A;  5AFH A;  4ILC A;  5HCJ A;  2BJ0 A;  4F8H A;  2Y56 A;  4HFI A;  2Y54 A;  4LMK A;  3JAF A;  2W8F A;  5HCM A;  3WTN A;  2WNL A;  2XQ7 A;  5HEG A;  3RHW A;  3UU5 A;  2XQ9 A;  3WTH A;  5CO5 A;  2ZJV A;  2WZY A;  4XK9 A;  5AFK A;  1UV6 A;  3UU3 A;  2PGZ A;  4HFD A;  5BRX A;  3PEO A;  2Y57 A;  2BR7 A;  4COF A;  5AFM B;  1I9B A;  5FJV A;  3ZDH A;  4LML A;  3T4M A;  4A97 A;  5AFN A;  2BYN A;  3U8L A;  3UUB A;  3RIA A;  5SYO A;  4Z91 A;  4ZJS A;  3LSV A;  3UU6 A;  2XNU A;  4XHE A;  2BYS A;  5KZU A;  2BG9 C;  3WTM A;  2XNV A;  4HQP A;  3WTL A;  2VL0 A;  3ZDG A;  4HFB A;  4FRR A;  4TWF A;  4B5D A;  3WIP A;  5LXB A;  2Y58 A;  3P4W A;  5LG3 A;  4ZR6 A;  4ZJT A;  3WTI A;  2W8G A;  3PMZ A;  5TVC A;  2BYQ A;  3RQW A;  3U8K A;  3EI0 A;  2XQ8 A;  3SIO A;  4HFH A;  3WTK A;  4IL4 A;  5KE4 A;  2XNT A;  4ZZB A;  3UQ7 A;  2YMD A;  5CFB A;  3ZKR A;  2BG9 E;  3SQ9 A;  2X00 A;  4D01 A;  4UM3 A;  4UM3 S;  2UZ6 A;  4PIR A;  4QAA A;  3U8M A;  2YOE A;  5L47 A;  3EAM A;  4IRE A;  3JAE A;  5HEH A;  3C79 A;  2BG9 A;  3TLS A;  5J5I A;  4BFQ A;  4NZB A;  2BR8 A;  4QAC A;  3RI5 A;  2Y7Y A;  4QH5 A;  4QH1 A;  5J5G A;  5L4H A;  4TWD A;  4IL9 A;  4X5T A;  4TNW A;  2C9T A;  3IGQ A;  4UY2 A;  2XQA A;  3TLV A;  3UU8 A;  4HFE A;  2YME A;  4A98 A;  3TLT A;  5IUX A;  3U8N A;  5J0Z A;  5HEO A;  4QH4 A;  3WTJ A;  2X00 D;  3UU4 A;  2QC1 B;  4TNV A;  4DBM A;  5BW2 A;  2XQ4 A;  4ALX A;  3C84 A;  4Z90 A;  4ZZC A;  2BG9 B;  4UM3 P;  2YN6 A;  4QAB A;  5BP0 A;  2XQ6 A;  4LMJ A;  5HEJ A;  5J5F A;  2BYP A;  2PH9 A;  4ILA A;  4ZRU A;  5JME A;  1UW6 A;  4EZ1 A;  3WTO A;  4TWH A;  5AIN A;  3SH1 A;  4NPP A;  2WNJ A;  4ILB A;  2XQ3 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...