2XYSA

Crystal structure of aplysia californica achbp in complex with strychnine
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
205
structure length
205
Chain Sequence
QANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKVDSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGVTCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Structural and Mutagenic Blueprint for Molecular Recognition of Strychnine and D-Tubocurarine by Different Cys-Loop Receptors.
pubmed doi rcsb
molecule tags Receptor
source organism Aplysia californica
molecule keywords SOLUBLE ACETYLCHOLINE RECEPTOR
total genus 48
structure length 205
sequence length 205
chains with identical sequence B, C, D, E
ec nomenclature
pdb deposition date 2010-11-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 2xysA00
5KE4A 4NPPA 5L4HA 5HEUA 4UM3S 2XQ9A 5TVCA 3UQ7A 2YMEA 1UW6A 2BG9B 2BYSA 2XQ7A 5J5GA 2XYSA 3C84A 4LMJA 3RQWA 3WTIA 2XNUA 3UU4A 4B5DA 2YMDA 4BFQA 3PMZA 2PGZA 3TLSA 4XHEA 4IL9A 5J5IA 5L4EA 3SQ6A 5SYOA 3EAMA 4TNVA 4TWDA 3WTMA 5HCMA 2Y57A 2XQ4A 3GUAA 3U8MA 2W8GA 2WN9A 4HFIA 3ZDHA 2BYPA 4TWFA 3TLVA 4FRRA 5HCJA 3UU3A 4D01A 5AFMA 5BP0A 4LMKA 3JADA 4ZZCA 4IL4A 3U8JA 4XK9A 3ZKRA 5KZUA 5AINA 2BR7A 5J0ZA 3WTHA 5AFMB 4QACA 2XQ3A 3UQ4A 3TLWA 5FJVA 4HFBA 2WZYA 3T4MA 3SIOA 3WTKA 2Y7YA 3SH1A 3WTNA 4TWHA 5LG3A 2XYTA 2XNTA 2Y56A 4COFA 5J5HA 4QABA 2ZJVA 3EI0A 2XZ6A 4LMLA 3P50A 4BQTA 2UZ6A 3UU6A 4UM3A 5BRXA 1I9BA 4ZJTA 2BYRA 4ALXA 4QAAA 5AFLA 3JAFA 4UY2A 4ILCA 2XNVA 3PEOA 3U8NA 4ILBA 1UV6A 4Z90A 3RQUA 3JAEA 4X5TA 2WNLA 4IREA 4A97A 4UM1A 2BG9E 3SQ9A 3U8KA 5AFKA 4ILAA 4QH5A 4WV9A 2WNCA 4NZBA 4HQPA 4ZK4A 2BG9C 4HFCA 2W8FA 5HEOA 3EHZA 4PIRA 3UUBA 3TLTA 5AFNA 2Y58A 4UXUA 5AFJA 4ZR6A 3IGQA 4ZK1A 4DBMA 2XQ8A 2YKSA 3WIPA 3WTLA 5BW2A 5HEHA 3RI5A 2VL0A 2XQ6A 5J5FA 2C9TA 2BJ0A 3U8LA 4TNWA 4ZJSA 2XZ5A 2BYNA 2BR8A 5AFHA 4ZZBA 3UU8A 3P4WA 2Y54A 2QC1B 3LSVA 3UU5A 2YN6A 3ZDGA 5CFBA 3RIFA 4Z91A 4ZRUA 2XQ5A 2WNJA 4A98A 2BYQA 4QH1A 5HEGA 2YOEA 3RHWA 4HFEA 4AFHA 2X00D 5IUXA 4UM3P 4AFTA 5HEJA 5JMEA 2X00A 5CO5A 3C79A 4HFDA 3WTJA 4HFHA 3WTOA 4EZ1A 2BG9A 4AFGA 4F8HA 3RIAA 5LXBA 1UX2A 2PH9A 3TLUA 4QH4A 5L47A 2XQAA 2ZJUA
chains in the Genus database with same CATH superfamily
5KE4A 4NPPA 5L4HA 5HEUA 4UM3S 2XQ9A 5TVCA 3UQ7A 2YMEA 1UW6A 2BG9B 2BYSA 2XQ7A 5J5GA 2XYSA 3C84A 4LMJA 3RQWA 3WTIA 2XNUA 3UU4A 4B5DA 2YMDA 4BFQA 3PMZA 2PGZA 3TLSA 4XHEA 4IL9A 5J5IA 5L4EA 3SQ6A 5SYOA 3EAMA 4TNVA 4TWDA 3WTMA 5HCMA 2Y57A 2XQ4A 3GUAA 3U8MA 2W8GA 2WN9A 4HFIA 3ZDHA 2BYPA 4TWFA 3TLVA 4FRRA 5HCJA 3UU3A 4D01A 5AFMA 5BP0A 4LMKA 3JADA 4ZZCA 4IL4A 3U8JA 4XK9A 3ZKRA 5KZUA 5AINA 2BR7A 5J0ZA 3WTHA 5AFMB 4QACA 2XQ3A 3UQ4A 3TLWA 5FJVA 4HFBA 2WZYA 3T4MA 3SIOA 3WTKA 2Y7YA 3SH1A 3WTNA 4TWHA 5LG3A 2XYTA 2XNTA 2Y56A 4COFA 5J5HA 4QABA 2ZJVA 3EI0A 2XZ6A 4LMLA 3P50A 4BQTA 2UZ6A 3UU6A 4UM3A 5BRXA 1I9BA 4ZJTA 2BYRA 4ALXA 4QAAA 5AFLA 3JAFA 4UY2A 4ILCA 2XNVA 3PEOA 3U8NA 4ILBA 1UV6A 4Z90A 3RQUA 3JAEA 4X5TA 2WNLA 4IREA 4A97A 4UM1A 2BG9E 3SQ9A 3U8KA 5AFKA 4ILAA 4QH5A 4WV9A 2WNCA 4NZBA 4HQPA 4ZK4A 2BG9C 4HFCA 2W8FA 5HEOA 3EHZA 4PIRA 3UUBA 3TLTA 5AFNA 2Y58A 4UXUA 5AFJA 4ZR6A 3IGQA 4ZK1A 4DBMA 2XQ8A 2YKSA 3WIPA 3WTLA 5BW2A 5HEHA 3RI5A 2VL0A 2XQ6A 5J5FA 2C9TA 2BJ0A 3U8LA 4TNWA 4ZJSA 2XZ5A 2BYNA 2BR8A 5AFHA 4ZZBA 3UU8A 3P4WA 2Y54A 2QC1B 3LSVA 3UU5A 2YN6A 3ZDGA 5CFBA 3RIFA 4Z91A 4ZRUA 2XQ5A 2WNJA 4A98A 2BYQA 4QH1A 5HEGA 2YOEA 3RHWA 4HFEA 4AFHA 2X00D 5IUXA 4UM3P 4AFTA 5HEJA 5JMEA 2X00A 5CO5A 3C79A 4HFDA 3WTJA 4HFHA 3WTOA 4EZ1A 2BG9A 4AFGA 4F8HA 3RIAA 5LXBA 1UX2A 2PH9A 3TLUA 4QH4A 5L47A 2XQAA 2ZJUA
chains in the Genus database with same CATH topology
5KE4A 4NPPA 5L4HA 5HEUA 4UM3S 2XQ9A 5TVCA 3UQ7A 2YMEA 1UW6A 2BG9B 2BYSA 2XQ7A 5J5GA 2XYSA 3C84A 4LMJA 3RQWA 3WTIA 2XNUA 3UU4A 4B5DA 2YMDA 4BFQA 3PMZA 2PGZA 3TLSA 4XHEA 4IL9A 5J5IA 5L4EA 3SQ6A 5SYOA 3EAMA 4TNVA 4TWDA 3WTMA 5HCMA 2Y57A 2XQ4A 3GUAA 3U8MA 2W8GA 2WN9A 4HFIA 3ZDHA 2BYPA 4TWFA 3TLVA 4FRRA 5HCJA 3UU3A 4D01A 5AFMA 5BP0A 4LMKA 3JADA 4ZZCA 4IL4A 3U8JA 4XK9A 3ZKRA 5KZUA 5AINA 2BR7A 5J0ZA 3WTHA 5AFMB 4QACA 2XQ3A 3UQ4A 3TLWA 5FJVA 4HFBA 2WZYA 3T4MA 3SIOA 3WTKA 2Y7YA 3SH1A 3WTNA 4TWHA 5LG3A 2XYTA 2XNTA 2Y56A 4COFA 5J5HA 4QABA 2ZJVA 3EI0A 2XZ6A 4LMLA 3P50A 4BQTA 2UZ6A 3UU6A 4UM3A 5BRXA 1I9BA 4ZJTA 2BYRA 4ALXA 4QAAA 5AFLA 3JAFA 4UY2A 4ILCA 2XNVA 3PEOA 3U8NA 4ILBA 1UV6A 4Z90A 3RQUA 3JAEA 4X5TA 2WNLA 4IREA 4A97A 4UM1A 2BG9E 3SQ9A 3U8KA 5AFKA 4ILAA 4QH5A 4WV9A 2WNCA 4NZBA 4HQPA 4ZK4A 2BG9C 4HFCA 2W8FA 5HEOA 3EHZA 4PIRA 3UUBA 3TLTA 5AFNA 2Y58A 4UXUA 5AFJA 4ZR6A 3IGQA 4ZK1A 4DBMA 2XQ8A 2YKSA 3WIPA 3WTLA 5BW2A 5HEHA 3RI5A 2VL0A 2XQ6A 5J5FA 2C9TA 2BJ0A 3U8LA 4TNWA 4ZJSA 2XZ5A 2BYNA 2BR8A 5AFHA 4ZZBA 3UU8A 3P4WA 2Y54A 2QC1B 3LSVA 3UU5A 2YN6A 3ZDGA 5CFBA 3RIFA 4Z91A 4ZRUA 2XQ5A 2WNJA 4A98A 2BYQA 4QH1A 5HEGA 2YOEA 3RHWA 4HFEA 4AFHA 2X00D 5IUXA 4UM3P 4AFTA 5HEJA 5JMEA 2X00A 5CO5A 3C79A 4HFDA 3WTJA 4HFHA 3WTOA 4EZ1A 2BG9A 4AFGA 4F8HA 3RIAA 5LXBA 1UX2A 2PH9A 3TLUA 4QH4A 5L47A 2XQAA 2ZJUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5KE4 A;  4NPP A;  5L4H A;  5HEU A;  4UM3 S;  2XQ9 A;  5TVC A;  3UQ7 A;  2YME A;  1UW6 A;  2BG9 B;  2BYS A;  2XQ7 A;  5J5G A;  2XYS A;  3C84 A;  4LMJ A;  3RQW A;  3WTI A;  2XNU A;  3UU4 A;  4B5D A;  2YMD A;  4BFQ A;  3PMZ A;  2PGZ A;  3TLS A;  4XHE A;  4IL9 A;  5J5I A;  5L4E A;  3SQ6 A;  5SYO A;  3EAM A;  4TNV A;  4TWD A;  3WTM A;  5HCM A;  2Y57 A;  2XQ4 A;  3GUA A;  3U8M A;  2W8G A;  2WN9 A;  4HFI A;  3ZDH A;  2BYP A;  4TWF A;  3TLV A;  4FRR A;  5HCJ A;  3UU3 A;  4D01 A;  5AFM A;  5BP0 A;  4LMK A;  3JAD A;  4ZZC A;  4IL4 A;  3U8J A;  4XK9 A;  3ZKR A;  5KZU A;  5AIN A;  2BR7 A;  5J0Z A;  3WTH A;  5AFM B;  4QAC A;  2XQ3 A;  3UQ4 A;  3TLW A;  5FJV A;  4HFB A;  2WZY A;  3T4M A;  3SIO A;  3WTK A;  2Y7Y A;  3SH1 A;  3WTN A;  4TWH A;  5LG3 A;  2XYT A;  2XNT A;  2Y56 A;  4COF A;  5J5H A;  4QAB A;  2ZJV A;  3EI0 A;  2XZ6 A;  4LML A;  3P50 A;  4BQT A;  2UZ6 A;  3UU6 A;  4UM3 A;  5BRX A;  1I9B A;  4ZJT A;  2BYR A;  4ALX A;  4QAA A;  5AFL A;  3JAF A;  4UY2 A;  4ILC A;  2XNV A;  3PEO A;  3U8N A;  4ILB A;  1UV6 A;  4Z90 A;  3RQU A;  3JAE A;  4X5T A;  2WNL A;  4IRE A;  4A97 A;  4UM1 A;  2BG9 E;  3SQ9 A;  3U8K A;  5AFK A;  4ILA A;  4QH5 A;  4WV9 A;  2WNC A;  4NZB A;  4HQP A;  4ZK4 A;  2BG9 C;  4HFC A;  2W8F A;  5HEO A;  3EHZ A;  4PIR A;  3UUB A;  3TLT A;  5AFN A;  2Y58 A;  4UXU A;  5AFJ A;  4ZR6 A;  3IGQ A;  4ZK1 A;  4DBM A;  2XQ8 A;  2YKS A;  3WIP A;  3WTL A;  5BW2 A;  5HEH A;  3RI5 A;  2VL0 A;  2XQ6 A;  5J5F A;  2C9T A;  2BJ0 A;  3U8L A;  4TNW A;  4ZJS A;  2XZ5 A;  2BYN A;  2BR8 A;  5AFH A;  4ZZB A;  3UU8 A;  3P4W A;  2Y54 A;  2QC1 B;  3LSV A;  3UU5 A;  2YN6 A;  3ZDG A;  5CFB A;  3RIF A;  4Z91 A;  4ZRU A;  2XQ5 A;  2WNJ A;  4A98 A;  2BYQ A;  4QH1 A;  5HEG A;  2YOE A;  3RHW A;  4HFE A;  4AFH A;  2X00 D;  5IUX A;  4UM3 P;  4AFT A;  5HEJ A;  5JME A;  2X00 A;  5CO5 A;  3C79 A;  4HFD A;  3WTJ A;  4HFH A;  3WTO A;  4EZ1 A;  2BG9 A;  4AFG A;  4F8H A;  3RIA A;  5LXB A;  1UX2 A;  2PH9 A;  3TLU A;  4QH4 A;  5L47 A;  2XQA A;  2ZJU A; 
#chains in the Genus database with same CATH topology
 5KE4 A;  4NPP A;  5L4H A;  5HEU A;  4UM3 S;  2XQ9 A;  5TVC A;  3UQ7 A;  2YME A;  1UW6 A;  2BG9 B;  2BYS A;  2XQ7 A;  5J5G A;  2XYS A;  3C84 A;  4LMJ A;  3RQW A;  3WTI A;  2XNU A;  3UU4 A;  4B5D A;  2YMD A;  4BFQ A;  3PMZ A;  2PGZ A;  3TLS A;  4XHE A;  4IL9 A;  5J5I A;  5L4E A;  3SQ6 A;  5SYO A;  3EAM A;  4TNV A;  4TWD A;  3WTM A;  5HCM A;  2Y57 A;  2XQ4 A;  3GUA A;  3U8M A;  2W8G A;  2WN9 A;  4HFI A;  3ZDH A;  2BYP A;  4TWF A;  3TLV A;  4FRR A;  5HCJ A;  3UU3 A;  4D01 A;  5AFM A;  5BP0 A;  4LMK A;  3JAD A;  4ZZC A;  4IL4 A;  3U8J A;  4XK9 A;  3ZKR A;  5KZU A;  5AIN A;  2BR7 A;  5J0Z A;  3WTH A;  5AFM B;  4QAC A;  2XQ3 A;  3UQ4 A;  3TLW A;  5FJV A;  4HFB A;  2WZY A;  3T4M A;  3SIO A;  3WTK A;  2Y7Y A;  3SH1 A;  3WTN A;  4TWH A;  5LG3 A;  2XYT A;  2XNT A;  2Y56 A;  4COF A;  5J5H A;  4QAB A;  2ZJV A;  3EI0 A;  2XZ6 A;  4LML A;  3P50 A;  4BQT A;  2UZ6 A;  3UU6 A;  4UM3 A;  5BRX A;  1I9B A;  4ZJT A;  2BYR A;  4ALX A;  4QAA A;  5AFL A;  3JAF A;  4UY2 A;  4ILC A;  2XNV A;  3PEO A;  3U8N A;  4ILB A;  1UV6 A;  4Z90 A;  3RQU A;  3JAE A;  4X5T A;  2WNL A;  4IRE A;  4A97 A;  4UM1 A;  2BG9 E;  3SQ9 A;  3U8K A;  5AFK A;  4ILA A;  4QH5 A;  4WV9 A;  2WNC A;  4NZB A;  4HQP A;  4ZK4 A;  2BG9 C;  4HFC A;  2W8F A;  5HEO A;  3EHZ A;  4PIR A;  3UUB A;  3TLT A;  5AFN A;  2Y58 A;  4UXU A;  5AFJ A;  4ZR6 A;  3IGQ A;  4ZK1 A;  4DBM A;  2XQ8 A;  2YKS A;  3WIP A;  3WTL A;  5BW2 A;  5HEH A;  3RI5 A;  2VL0 A;  2XQ6 A;  5J5F A;  2C9T A;  2BJ0 A;  3U8L A;  4TNW A;  4ZJS A;  2XZ5 A;  2BYN A;  2BR8 A;  5AFH A;  4ZZB A;  3UU8 A;  3P4W A;  2Y54 A;  2QC1 B;  3LSV A;  3UU5 A;  2YN6 A;  3ZDG A;  5CFB A;  3RIF A;  4Z91 A;  4ZRU A;  2XQ5 A;  2WNJ A;  4A98 A;  2BYQ A;  4QH1 A;  5HEG A;  2YOE A;  3RHW A;  4HFE A;  4AFH A;  2X00 D;  5IUX A;  4UM3 P;  4AFT A;  5HEJ A;  5JME A;  2X00 A;  5CO5 A;  3C79 A;  4HFD A;  3WTJ A;  4HFH A;  3WTO A;  4EZ1 A;  2BG9 A;  4AFG A;  4F8H A;  3RIA A;  5LXB A;  1UX2 A;  2PH9 A;  3TLU A;  4QH4 A;  5L47 A;  2XQA A;  2ZJU A; 
#chains in the Genus database with same CATH homology
 5KE4 A;  4NPP A;  5L4H A;  5HEU A;  4UM3 S;  2XQ9 A;  5TVC A;  3UQ7 A;  2YME A;  1UW6 A;  2BG9 B;  2BYS A;  2XQ7 A;  5J5G A;  2XYS A;  3C84 A;  4LMJ A;  3RQW A;  3WTI A;  2XNU A;  3UU4 A;  4B5D A;  2YMD A;  4BFQ A;  3PMZ A;  2PGZ A;  3TLS A;  4XHE A;  4IL9 A;  5J5I A;  5L4E A;  3SQ6 A;  5SYO A;  3EAM A;  4TNV A;  4TWD A;  3WTM A;  5HCM A;  2Y57 A;  2XQ4 A;  3GUA A;  3U8M A;  2W8G A;  2WN9 A;  4HFI A;  3ZDH A;  2BYP A;  4TWF A;  3TLV A;  4FRR A;  5HCJ A;  3UU3 A;  4D01 A;  5AFM A;  5BP0 A;  4LMK A;  3JAD A;  4ZZC A;  4IL4 A;  3U8J A;  4XK9 A;  3ZKR A;  5KZU A;  5AIN A;  2BR7 A;  5J0Z A;  3WTH A;  5AFM B;  4QAC A;  2XQ3 A;  3UQ4 A;  3TLW A;  5FJV A;  4HFB A;  2WZY A;  3T4M A;  3SIO A;  3WTK A;  2Y7Y A;  3SH1 A;  3WTN A;  4TWH A;  5LG3 A;  2XYT A;  2XNT A;  2Y56 A;  4COF A;  5J5H A;  4QAB A;  2ZJV A;  3EI0 A;  2XZ6 A;  4LML A;  3P50 A;  4BQT A;  2UZ6 A;  3UU6 A;  4UM3 A;  5BRX A;  1I9B A;  4ZJT A;  2BYR A;  4ALX A;  4QAA A;  5AFL A;  3JAF A;  4UY2 A;  4ILC A;  2XNV A;  3PEO A;  3U8N A;  4ILB A;  1UV6 A;  4Z90 A;  3RQU A;  3JAE A;  4X5T A;  2WNL A;  4IRE A;  4A97 A;  4UM1 A;  2BG9 E;  3SQ9 A;  3U8K A;  5AFK A;  4ILA A;  4QH5 A;  4WV9 A;  2WNC A;  4NZB A;  4HQP A;  4ZK4 A;  2BG9 C;  4HFC A;  2W8F A;  5HEO A;  3EHZ A;  4PIR A;  3UUB A;  3TLT A;  5AFN A;  2Y58 A;  4UXU A;  5AFJ A;  4ZR6 A;  3IGQ A;  4ZK1 A;  4DBM A;  2XQ8 A;  2YKS A;  3WIP A;  3WTL A;  5BW2 A;  5HEH A;  3RI5 A;  2VL0 A;  2XQ6 A;  5J5F A;  2C9T A;  2BJ0 A;  3U8L A;  4TNW A;  4ZJS A;  2XZ5 A;  2BYN A;  2BR8 A;  5AFH A;  4ZZB A;  3UU8 A;  3P4W A;  2Y54 A;  2QC1 B;  3LSV A;  3UU5 A;  2YN6 A;  3ZDG A;  5CFB A;  3RIF A;  4Z91 A;  4ZRU A;  2XQ5 A;  2WNJ A;  4A98 A;  2BYQ A;  4QH1 A;  5HEG A;  2YOE A;  3RHW A;  4HFE A;  4AFH A;  2X00 D;  5IUX A;  4UM3 P;  4AFT A;  5HEJ A;  5JME A;  2X00 A;  5CO5 A;  3C79 A;  4HFD A;  3WTJ A;  4HFH A;  3WTO A;  4EZ1 A;  2BG9 A;  4AFG A;  4F8H A;  3RIA A;  5LXB A;  1UX2 A;  2PH9 A;  3TLU A;  4QH4 A;  5L47 A;  2XQA A;  2ZJU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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