2XYSA

Crystal structure of aplysia californica achbp in complex with strychnine
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
205
structure length
205
Chain Sequence
QANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKVDSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGVTCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Receptor
source organism Aplysia californica
publication title A Structural and Mutagenic Blueprint for Molecular Recognition of Strychnine and D-Tubocurarine by Different Cys-Loop Receptors.
pubmed doi rcsb
molecule keywords SOLUBLE ACETYLCHOLINE RECEPTOR
total genus 48
structure length 205
sequence length 205
chains with identical sequence B, C, D, E
ec nomenclature
pdb deposition date 2010-11-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 2xysA00
2WNCA 1UW6A 5J5HA 2C9TA 2XQ6A 2XQAA 4QH1A 5CFBA 3WTOA 3ZKRA 4QH4A 3U8NA 3EI0A 3RIAA 2YN6A 2YMEA 4PIRA 4B5DA 2X00D 2XNUA 4HFEA 3WTNA 3UQ7A 4X5TA 3SIOA 2XQ7A 4NZBA 4BFQA 2BYQA 3WTIA 4ILAA 2BYPA 2XNVA 2WNJA 4A97A 4AFHA 2XQ4A 4UM3A 3U8LA 2PGZA 3TLVA 4UY2A 4LMLA 4EZ1A 4ZK1A 5AFMB 4HFCA 2BJ0A 3UQ4A 3UU3A 2XZ5A 4ZRUA 2YMDA 4LMKA 5IUXA 3ZDGA 2BYRA 4XHEA 2XYTA 2WZYA 4IL9A 4TWDA 4FRRA 4ALXA 2YOEA 4IL4A 3P4WA 4ZJTA 5CO5A 4D01A 3U8JA 4QH5A 4IREA 2BG9E 4QACA 2BG9C 5JMEA 4COFA 2BR7A 2WN9A 4TWHA 4Z90A 5LG3A 2ZJVA 2Y7YA 2XNTA 4QAAA 4ZR6A 5HEGA 3PEOA 3SQ9A 5AINA 4TWFA 2Y54A 4TNVA 4HFHA 5L4EA 5BRXA 3U8MA 1UV6A 4AFTA 4Z91A 3RQWA 4AFGA 4UXUA 5HEJA 5HCJA 2BYNA 2BG9A 4TNWA 4DBMA 3UU8A 2Y58A 2BYSA 3RQUA 3JADA 5SYOA 4UM3S 5J5GA 4XK9A 3WTHA 3JAEA 4UM1A 4WV9A 4A98A 2BR8A 3PMZA 5HEUA 3U8KA 3UU4A 3WTMA 3SH1A 3LSVA 5L4HA 4ZJSA 2YKSA 3TLUA 3UUBA 5KE4A 2W8GA 3C79A 4HFBA 3IGQA 4HQPA 4LMJA 4UM3P 5AFJA 3WTLA 3P50A 2ZJUA 4ILBA 2XQ3A 2Y56A 3C84A 2XQ5A 2WNLA 4QABA 2VL0A 3RHWA 3TLTA 5AFHA 2XZ6A 3WTKA 3SQ6A 4ZK4A 2PH9A 5J0ZA 5AFNA 3EAMA 2XYSA 5KZUA 3RI5A 3ZDHA 5HEHA 3RIFA 3UU6A 5AFKA 3UU5A 5FJVA 4BQTA 5L47A 4HFIA 5HEOA 4ZZBA 4ZZCA 5AFMA 5BP0A 5J5IA 2X00A 3GUAA 2QC1B 5AFLA 3T4MA 5BW2A 2BG9B 4F8HA 3JAFA 2Y57A 4HFDA 4ILCA 3WTJA 2XQ8A 1I9BA 2UZ6A 3TLWA 1UX2A 3TLSA 5J5FA 5HCMA 4NPPA 2W8FA 2XQ9A 5LXBA 3EHZA 3WIPA 5TVCA
chains in the Genus database with same CATH superfamily
2WNCA 1UW6A 5J5HA 2C9TA 2XQ6A 2XQAA 4QH1A 5CFBA 3WTOA 3ZKRA 4QH4A 3U8NA 3EI0A 3RIAA 2YN6A 2YMEA 4PIRA 4B5DA 2X00D 2XNUA 4HFEA 3WTNA 3UQ7A 4X5TA 3SIOA 2XQ7A 4NZBA 4BFQA 2BYQA 3WTIA 4ILAA 2BYPA 2XNVA 2WNJA 4A97A 4AFHA 2XQ4A 4UM3A 3U8LA 2PGZA 3TLVA 4UY2A 4LMLA 4EZ1A 4ZK1A 5AFMB 4HFCA 2BJ0A 3UQ4A 3UU3A 2XZ5A 4ZRUA 2YMDA 4LMKA 5IUXA 3ZDGA 2BYRA 4XHEA 2XYTA 2WZYA 4IL9A 4TWDA 4FRRA 4ALXA 2YOEA 4IL4A 3P4WA 4ZJTA 5CO5A 4D01A 3U8JA 4QH5A 4IREA 2BG9E 4QACA 2BG9C 5JMEA 4COFA 2BR7A 2WN9A 4TWHA 4Z90A 5LG3A 2ZJVA 2Y7YA 2XNTA 4QAAA 4ZR6A 5HEGA 3PEOA 3SQ9A 5AINA 4TWFA 2Y54A 4TNVA 4HFHA 5L4EA 5BRXA 3U8MA 1UV6A 4AFTA 4Z91A 3RQWA 4AFGA 4UXUA 5HEJA 5HCJA 2BYNA 2BG9A 4TNWA 4DBMA 3UU8A 2Y58A 2BYSA 3RQUA 3JADA 5SYOA 4UM3S 5J5GA 4XK9A 3WTHA 3JAEA 4UM1A 4WV9A 4A98A 2BR8A 3PMZA 5HEUA 3U8KA 3UU4A 3WTMA 3SH1A 3LSVA 5L4HA 4ZJSA 2YKSA 3TLUA 3UUBA 5KE4A 2W8GA 3C79A 4HFBA 3IGQA 4HQPA 4LMJA 4UM3P 5AFJA 3WTLA 3P50A 2ZJUA 4ILBA 2XQ3A 2Y56A 3C84A 2XQ5A 2WNLA 4QABA 2VL0A 3RHWA 3TLTA 5AFHA 2XZ6A 3WTKA 3SQ6A 4ZK4A 2PH9A 5J0ZA 5AFNA 3EAMA 2XYSA 5KZUA 3RI5A 3ZDHA 5HEHA 3RIFA 3UU6A 5AFKA 3UU5A 5FJVA 4BQTA 5L47A 4HFIA 5HEOA 4ZZBA 4ZZCA 5AFMA 5BP0A 5J5IA 2X00A 3GUAA 2QC1B 5AFLA 3T4MA 5BW2A 2BG9B 4F8HA 3JAFA 2Y57A 4HFDA 4ILCA 3WTJA 2XQ8A 1I9BA 2UZ6A 3TLWA 1UX2A 3TLSA 5J5FA 5HCMA 4NPPA 2W8FA 2XQ9A 5LXBA 3EHZA 3WIPA 5TVCA
chains in the Genus database with same CATH topology
2WNCA 1UW6A 5J5HA 2C9TA 2XQ6A 2XQAA 4QH1A 5CFBA 3WTOA 3ZKRA 4QH4A 3U8NA 3EI0A 3RIAA 2YN6A 2YMEA 4PIRA 4B5DA 2X00D 2XNUA 4HFEA 3WTNA 3UQ7A 4X5TA 3SIOA 2XQ7A 4NZBA 4BFQA 2BYQA 3WTIA 4ILAA 2BYPA 2XNVA 2WNJA 4A97A 4AFHA 2XQ4A 4UM3A 3U8LA 2PGZA 3TLVA 4UY2A 4LMLA 4EZ1A 4ZK1A 5AFMB 4HFCA 2BJ0A 3UQ4A 3UU3A 2XZ5A 4ZRUA 2YMDA 4LMKA 5IUXA 3ZDGA 2BYRA 4XHEA 2XYTA 2WZYA 4IL9A 4TWDA 4FRRA 4ALXA 2YOEA 4IL4A 3P4WA 4ZJTA 5CO5A 4D01A 3U8JA 4QH5A 4IREA 2BG9E 4QACA 2BG9C 5JMEA 4COFA 2BR7A 2WN9A 4TWHA 4Z90A 5LG3A 2ZJVA 2Y7YA 2XNTA 4QAAA 4ZR6A 5HEGA 3PEOA 3SQ9A 5AINA 4TWFA 2Y54A 4TNVA 4HFHA 5L4EA 5BRXA 3U8MA 1UV6A 4AFTA 4Z91A 3RQWA 4AFGA 4UXUA 5HEJA 5HCJA 2BYNA 2BG9A 4TNWA 4DBMA 3UU8A 2Y58A 2BYSA 3RQUA 3JADA 5SYOA 4UM3S 5J5GA 4XK9A 3WTHA 3JAEA 4UM1A 4WV9A 4A98A 2BR8A 3PMZA 5HEUA 3U8KA 3UU4A 3WTMA 3SH1A 3LSVA 5L4HA 4ZJSA 2YKSA 3TLUA 3UUBA 5KE4A 2W8GA 3C79A 4HFBA 3IGQA 4HQPA 4LMJA 4UM3P 5AFJA 3WTLA 3P50A 2ZJUA 4ILBA 2XQ3A 2Y56A 3C84A 2XQ5A 2WNLA 4QABA 2VL0A 3RHWA 3TLTA 5AFHA 2XZ6A 3WTKA 3SQ6A 4ZK4A 2PH9A 5J0ZA 5AFNA 3EAMA 2XYSA 5KZUA 3RI5A 3ZDHA 5HEHA 3RIFA 3UU6A 5AFKA 3UU5A 5FJVA 4BQTA 5L47A 4HFIA 5HEOA 4ZZBA 4ZZCA 5AFMA 5BP0A 5J5IA 2X00A 3GUAA 2QC1B 5AFLA 3T4MA 5BW2A 2BG9B 4F8HA 3JAFA 2Y57A 4HFDA 4ILCA 3WTJA 2XQ8A 1I9BA 2UZ6A 3TLWA 1UX2A 3TLSA 5J5FA 5HCMA 4NPPA 2W8FA 2XQ9A 5LXBA 3EHZA 3WIPA 5TVCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WNC A;  1UW6 A;  5J5H A;  2C9T A;  2XQ6 A;  2XQA A;  4QH1 A;  5CFB A;  3WTO A;  3ZKR A;  4QH4 A;  3U8N A;  3EI0 A;  3RIA A;  2YN6 A;  2YME A;  4PIR A;  4B5D A;  2X00 D;  2XNU A;  4HFE A;  3WTN A;  3UQ7 A;  4X5T A;  3SIO A;  2XQ7 A;  4NZB A;  4BFQ A;  2BYQ A;  3WTI A;  4ILA A;  2BYP A;  2XNV A;  2WNJ A;  4A97 A;  4AFH A;  2XQ4 A;  4UM3 A;  3U8L A;  2PGZ A;  3TLV A;  4UY2 A;  4LML A;  4EZ1 A;  4ZK1 A;  5AFM B;  4HFC A;  2BJ0 A;  3UQ4 A;  3UU3 A;  2XZ5 A;  4ZRU A;  2YMD A;  4LMK A;  5IUX A;  3ZDG A;  2BYR A;  4XHE A;  2XYT A;  2WZY A;  4IL9 A;  4TWD A;  4FRR A;  4ALX A;  2YOE A;  4IL4 A;  3P4W A;  4ZJT A;  5CO5 A;  4D01 A;  3U8J A;  4QH5 A;  4IRE A;  2BG9 E;  4QAC A;  2BG9 C;  5JME A;  4COF A;  2BR7 A;  2WN9 A;  4TWH A;  4Z90 A;  5LG3 A;  2ZJV A;  2Y7Y A;  2XNT A;  4QAA A;  4ZR6 A;  5HEG A;  3PEO A;  3SQ9 A;  5AIN A;  4TWF A;  2Y54 A;  4TNV A;  4HFH A;  5L4E A;  5BRX A;  3U8M A;  1UV6 A;  4AFT A;  4Z91 A;  3RQW A;  4AFG A;  4UXU A;  5HEJ A;  5HCJ A;  2BYN A;  2BG9 A;  4TNW A;  4DBM A;  3UU8 A;  2Y58 A;  2BYS A;  3RQU A;  3JAD A;  5SYO A;  4UM3 S;  5J5G A;  4XK9 A;  3WTH A;  3JAE A;  4UM1 A;  4WV9 A;  4A98 A;  2BR8 A;  3PMZ A;  5HEU A;  3U8K A;  3UU4 A;  3WTM A;  3SH1 A;  3LSV A;  5L4H A;  4ZJS A;  2YKS A;  3TLU A;  3UUB A;  5KE4 A;  2W8G A;  3C79 A;  4HFB A;  3IGQ A;  4HQP A;  4LMJ A;  4UM3 P;  5AFJ A;  3WTL A;  3P50 A;  2ZJU A;  4ILB A;  2XQ3 A;  2Y56 A;  3C84 A;  2XQ5 A;  2WNL A;  4QAB A;  2VL0 A;  3RHW A;  3TLT A;  5AFH A;  2XZ6 A;  3WTK A;  3SQ6 A;  4ZK4 A;  2PH9 A;  5J0Z A;  5AFN A;  3EAM A;  2XYS A;  5KZU A;  3RI5 A;  3ZDH A;  5HEH A;  3RIF A;  3UU6 A;  5AFK A;  3UU5 A;  5FJV A;  4BQT A;  5L47 A;  4HFI A;  5HEO A;  4ZZB A;  4ZZC A;  5AFM A;  5BP0 A;  5J5I A;  2X00 A;  3GUA A;  2QC1 B;  5AFL A;  3T4M A;  5BW2 A;  2BG9 B;  4F8H A;  3JAF A;  2Y57 A;  4HFD A;  4ILC A;  3WTJ A;  2XQ8 A;  1I9B A;  2UZ6 A;  3TLW A;  1UX2 A;  3TLS A;  5J5F A;  5HCM A;  4NPP A;  2W8F A;  2XQ9 A;  5LXB A;  3EHZ A;  3WIP A;  5TVC A; 
#chains in the Genus database with same CATH topology
 2WNC A;  1UW6 A;  5J5H A;  2C9T A;  2XQ6 A;  2XQA A;  4QH1 A;  5CFB A;  3WTO A;  3ZKR A;  4QH4 A;  3U8N A;  3EI0 A;  3RIA A;  2YN6 A;  2YME A;  4PIR A;  4B5D A;  2X00 D;  2XNU A;  4HFE A;  3WTN A;  3UQ7 A;  4X5T A;  3SIO A;  2XQ7 A;  4NZB A;  4BFQ A;  2BYQ A;  3WTI A;  4ILA A;  2BYP A;  2XNV A;  2WNJ A;  4A97 A;  4AFH A;  2XQ4 A;  4UM3 A;  3U8L A;  2PGZ A;  3TLV A;  4UY2 A;  4LML A;  4EZ1 A;  4ZK1 A;  5AFM B;  4HFC A;  2BJ0 A;  3UQ4 A;  3UU3 A;  2XZ5 A;  4ZRU A;  2YMD A;  4LMK A;  5IUX A;  3ZDG A;  2BYR A;  4XHE A;  2XYT A;  2WZY A;  4IL9 A;  4TWD A;  4FRR A;  4ALX A;  2YOE A;  4IL4 A;  3P4W A;  4ZJT A;  5CO5 A;  4D01 A;  3U8J A;  4QH5 A;  4IRE A;  2BG9 E;  4QAC A;  2BG9 C;  5JME A;  4COF A;  2BR7 A;  2WN9 A;  4TWH A;  4Z90 A;  5LG3 A;  2ZJV A;  2Y7Y A;  2XNT A;  4QAA A;  4ZR6 A;  5HEG A;  3PEO A;  3SQ9 A;  5AIN A;  4TWF A;  2Y54 A;  4TNV A;  4HFH A;  5L4E A;  5BRX A;  3U8M A;  1UV6 A;  4AFT A;  4Z91 A;  3RQW A;  4AFG A;  4UXU A;  5HEJ A;  5HCJ A;  2BYN A;  2BG9 A;  4TNW A;  4DBM A;  3UU8 A;  2Y58 A;  2BYS A;  3RQU A;  3JAD A;  5SYO A;  4UM3 S;  5J5G A;  4XK9 A;  3WTH A;  3JAE A;  4UM1 A;  4WV9 A;  4A98 A;  2BR8 A;  3PMZ A;  5HEU A;  3U8K A;  3UU4 A;  3WTM A;  3SH1 A;  3LSV A;  5L4H A;  4ZJS A;  2YKS A;  3TLU A;  3UUB A;  5KE4 A;  2W8G A;  3C79 A;  4HFB A;  3IGQ A;  4HQP A;  4LMJ A;  4UM3 P;  5AFJ A;  3WTL A;  3P50 A;  2ZJU A;  4ILB A;  2XQ3 A;  2Y56 A;  3C84 A;  2XQ5 A;  2WNL A;  4QAB A;  2VL0 A;  3RHW A;  3TLT A;  5AFH A;  2XZ6 A;  3WTK A;  3SQ6 A;  4ZK4 A;  2PH9 A;  5J0Z A;  5AFN A;  3EAM A;  2XYS A;  5KZU A;  3RI5 A;  3ZDH A;  5HEH A;  3RIF A;  3UU6 A;  5AFK A;  3UU5 A;  5FJV A;  4BQT A;  5L47 A;  4HFI A;  5HEO A;  4ZZB A;  4ZZC A;  5AFM A;  5BP0 A;  5J5I A;  2X00 A;  3GUA A;  2QC1 B;  5AFL A;  3T4M A;  5BW2 A;  2BG9 B;  4F8H A;  3JAF A;  2Y57 A;  4HFD A;  4ILC A;  3WTJ A;  2XQ8 A;  1I9B A;  2UZ6 A;  3TLW A;  1UX2 A;  3TLS A;  5J5F A;  5HCM A;  4NPP A;  2W8F A;  2XQ9 A;  5LXB A;  3EHZ A;  3WIP A;  5TVC A; 
#chains in the Genus database with same CATH homology
 2WNC A;  1UW6 A;  5J5H A;  2C9T A;  2XQ6 A;  2XQA A;  4QH1 A;  5CFB A;  3WTO A;  3ZKR A;  4QH4 A;  3U8N A;  3EI0 A;  3RIA A;  2YN6 A;  2YME A;  4PIR A;  4B5D A;  2X00 D;  2XNU A;  4HFE A;  3WTN A;  3UQ7 A;  4X5T A;  3SIO A;  2XQ7 A;  4NZB A;  4BFQ A;  2BYQ A;  3WTI A;  4ILA A;  2BYP A;  2XNV A;  2WNJ A;  4A97 A;  4AFH A;  2XQ4 A;  4UM3 A;  3U8L A;  2PGZ A;  3TLV A;  4UY2 A;  4LML A;  4EZ1 A;  4ZK1 A;  5AFM B;  4HFC A;  2BJ0 A;  3UQ4 A;  3UU3 A;  2XZ5 A;  4ZRU A;  2YMD A;  4LMK A;  5IUX A;  3ZDG A;  2BYR A;  4XHE A;  2XYT A;  2WZY A;  4IL9 A;  4TWD A;  4FRR A;  4ALX A;  2YOE A;  4IL4 A;  3P4W A;  4ZJT A;  5CO5 A;  4D01 A;  3U8J A;  4QH5 A;  4IRE A;  2BG9 E;  4QAC A;  2BG9 C;  5JME A;  4COF A;  2BR7 A;  2WN9 A;  4TWH A;  4Z90 A;  5LG3 A;  2ZJV A;  2Y7Y A;  2XNT A;  4QAA A;  4ZR6 A;  5HEG A;  3PEO A;  3SQ9 A;  5AIN A;  4TWF A;  2Y54 A;  4TNV A;  4HFH A;  5L4E A;  5BRX A;  3U8M A;  1UV6 A;  4AFT A;  4Z91 A;  3RQW A;  4AFG A;  4UXU A;  5HEJ A;  5HCJ A;  2BYN A;  2BG9 A;  4TNW A;  4DBM A;  3UU8 A;  2Y58 A;  2BYS A;  3RQU A;  3JAD A;  5SYO A;  4UM3 S;  5J5G A;  4XK9 A;  3WTH A;  3JAE A;  4UM1 A;  4WV9 A;  4A98 A;  2BR8 A;  3PMZ A;  5HEU A;  3U8K A;  3UU4 A;  3WTM A;  3SH1 A;  3LSV A;  5L4H A;  4ZJS A;  2YKS A;  3TLU A;  3UUB A;  5KE4 A;  2W8G A;  3C79 A;  4HFB A;  3IGQ A;  4HQP A;  4LMJ A;  4UM3 P;  5AFJ A;  3WTL A;  3P50 A;  2ZJU A;  4ILB A;  2XQ3 A;  2Y56 A;  3C84 A;  2XQ5 A;  2WNL A;  4QAB A;  2VL0 A;  3RHW A;  3TLT A;  5AFH A;  2XZ6 A;  3WTK A;  3SQ6 A;  4ZK4 A;  2PH9 A;  5J0Z A;  5AFN A;  3EAM A;  2XYS A;  5KZU A;  3RI5 A;  3ZDH A;  5HEH A;  3RIF A;  3UU6 A;  5AFK A;  3UU5 A;  5FJV A;  4BQT A;  5L47 A;  4HFI A;  5HEO A;  4ZZB A;  4ZZC A;  5AFM A;  5BP0 A;  5J5I A;  2X00 A;  3GUA A;  2QC1 B;  5AFL A;  3T4M A;  5BW2 A;  2BG9 B;  4F8H A;  3JAF A;  2Y57 A;  4HFD A;  4ILC A;  3WTJ A;  2XQ8 A;  1I9B A;  2UZ6 A;  3TLW A;  1UX2 A;  3TLS A;  5J5F A;  5HCM A;  4NPP A;  2W8F A;  2XQ9 A;  5LXB A;  3EHZ A;  3WIP A;  5TVC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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