2Y57 | Genus

Total Genus 44

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	44
sequence length	205
structure length	205
Chain Sequence	QANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKVDSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGVTCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Receptor
source organism	Aplysia californica
publication title	Fragment Growing Induces Conformational Changes in Acetylcholine-Binding Protein: A Structural and Thermodynamic Analysis. pubmed doi rcsb
molecule keywords	SOLUBLE ACETYLCHOLINE RECEPTOR
total genus	44
structure length	205
sequence length	205
chains with identical sequence	B, C, D, E
ec nomenclature
pdb deposition date	2011-01-12

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF02931	Neur_chan_LBD	Neurotransmitter-gated ion-channel ligand binding domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.70.170.10	Mainly Beta	Distorted Sandwich	Acetylcholine Binding Protein; Chain: A,	Neurotransmitter-gated ion-channel ligand-binding domain	2y57A00

2WNCA 3SH1A 3RQWA 2XZ6A 5AFMA 2XQ7A 2BYPA 2BR8A 4TWDA 3SQ6A 4A98A 2YKSA 4XK9A 5AFLA 2BG9C 4NPPA 4LMJA 5AFKA 3LSVA 5CFBA 4ZK1A 2XYSA 2XQ3A 3TLUA 5HEUA 3RHWA 2W8GA 5IUXA 3P4WA 4HFBA 5BW2A 3T4MA 4Z90A 5L4EA 3TLSA 4QABA 4ZRUA 3SIOA 2XQ5A 1UW6A 3EI0A 4HQPA 3UU3A 4QAAA 2XNTA 4COFA 4ILCA 4UM3P 2YMDA 3WTJA 4IREA 4A97A 1UV6A 3ZDGA 5L47A 2BG9E 3WTHA 2YMEA 2XNVA 5KE4A 4IL9A 4QH5A 3U8LA 4AFTA 3ZKRA 4AFHA 3EAMA 3PMZA 4ZJSA 2QC1B 5HCMA 4AFGA 2Y57A 3WTIA 4DBMA 4UM3S 2X00A 3UUBA 3C79A 2Y7YA 3WIPA 3RQUA 3RIFA 1I9BA 3UU6A 4ZJTA 4X5TA 2BG9A 4PIRA 4UM3A 5HCJA 5FJVA 5CO5A 2ZJUA 3U8MA 2BYQA 3WTOA 4NZBA 4UM1A 2BJ0A 5J0ZA 2XYTA 4HFCA 2WNLA 3JAEA 3TLWA 2W8FA 3C84A 5AFMB 2XQAA 4ILAA 2XQ8A 4WV9A 3U8JA 3WTMA 2PGZA 3UU4A 2XQ6A 2Y56A 2X00D 4ZR6A 5J5FA 4TWFA 4BQTA 2XQ9A 4TNWA 5HEOA 2BYNA 5SYOA 4QH4A 3U8KA 3UQ4A 2WN9A 3UU5A 4LMKA 4HFEA 3P50A 5J5GA 4HFHA 4B5DA 4F8HA 4HFDA 3TLVA 4ZZCA 4QH1A 4HFIA 4ILBA 4FRRA 4LMLA 5HEJA 5BRXA 5AFHA 2BG9B 4UY2A 5TVCA 2Y54A 3WTNA 4Z91A 3SQ9A 3EHZA 3RIAA 2BR7A 2XZ5A 2XQ4A 3WTLA 3WTKA 5J5IA 2C9TA 2UZ6A 5AINA 3JAFA 3RI5A 4BFQA 3PEOA 3U8NA 2VL0A 5LG3A 5HEHA 2WNJA 5L4HA 2WZYA 4TWHA 5AFJA 5J5HA 5BP0A 2ZJVA 4ZZBA 3GUAA 2BYSA 5LXBA 2XNUA 2PH9A 4ZK4A 2Y58A 2YOEA 3JADA 4D01A 4EZ1A 5HEGA 3IGQA 5AFNA 4IL4A 3UQ7A 2YN6A 4QACA 4UXUA 1UX2A 2BYRA 5KZUA 4ALXA 4TNVA 5JMEA 3TLTA 3ZDHA 3UU8A 4XHEA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 2WNC A;  3SH1 A;  3RQW A;  2XZ6 A;  5AFM A;  2XQ7 A;  2BYP A;  2BR8 A;  4TWD A;  3SQ6 A;  4A98 A;  2YKS A;  4XK9 A;  5AFL A;  2BG9 C;  4NPP A;  4LMJ A;  5AFK A;  3LSV A;  5CFB A;  4ZK1 A;  2XYS A;  2XQ3 A;  3TLU A;  5HEU A;  3RHW A;  2W8G A;  5IUX A;  3P4W A;  4HFB A;  5BW2 A;  3T4M A;  4Z90 A;  5L4E A;  3TLS A;  4QAB A;  4ZRU A;  3SIO A;  2XQ5 A;  1UW6 A;  3EI0 A;  4HQP A;  3UU3 A;  4QAA A;  2XNT A;  4COF A;  4ILC A;  4UM3 P;  2YMD A;  3WTJ A;  4IRE A;  4A97 A;  1UV6 A;  3ZDG A;  5L47 A;  2BG9 E;  3WTH A;  2YME A;  2XNV A;  5KE4 A;  4IL9 A;  4QH5 A;  3U8L A;  4AFT A;  3ZKR A;  4AFH A;  3EAM A;  3PMZ A;  4ZJS A;  2QC1 B;  5HCM A;  4AFG A;  2Y57 A;  3WTI A;  4DBM A;  4UM3 S;  2X00 A;  3UUB A;  3C79 A;  2Y7Y A;  3WIP A;  3RQU A;  3RIF A;  1I9B A;  3UU6 A;  4ZJT A;  4X5T A;  2BG9 A;  4PIR A;  4UM3 A;  5HCJ A;  5FJV A;  5CO5 A;  2ZJU A;  3U8M A;  2BYQ A;  3WTO A;  4NZB A;  4UM1 A;  2BJ0 A;  5J0Z A;  2XYT A;  4HFC A;  2WNL A;  3JAE A;  3TLW A;  2W8F A;  3C84 A;  5AFM B;  2XQA A;  4ILA A;  2XQ8 A;  4WV9 A;  3U8J A;  3WTM A;  2PGZ A;  3UU4 A;  2XQ6 A;  2Y56 A;  2X00 D;  4ZR6 A;  5J5F A;  4TWF A;  4BQT A;  2XQ9 A;  4TNW A;  5HEO A;  2BYN A;  5SYO A;  4QH4 A;  3U8K A;  3UQ4 A;  2WN9 A;  3UU5 A;  4LMK A;  4HFE A;  3P50 A;  5J5G A;  4HFH A;  4B5D A;  4F8H A;  4HFD A;  3TLV A;  4ZZC A;  4QH1 A;  4HFI A;  4ILB A;  4FRR A;  4LML A;  5HEJ A;  5BRX A;  5AFH A;  2BG9 B;  4UY2 A;  5TVC A;  2Y54 A;  3WTN A;  4Z91 A;  3SQ9 A;  3EHZ A;  3RIA A;  2BR7 A;  2XZ5 A;  2XQ4 A;  3WTL A;  3WTK A;  5J5I A;  2C9T A;  2UZ6 A;  5AIN A;  3JAF A;  3RI5 A;  4BFQ A;  3PEO A;  3U8N A;  2VL0 A;  5LG3 A;  5HEH A;  2WNJ A;  5L4H A;  2WZY A;  4TWH A;  5AFJ A;  5J5H A;  5BP0 A;  2ZJV A;  4ZZB A;  3GUA A;  2BYS A;  5LXB A;  2XNU A;  2PH9 A;  4ZK4 A;  2Y58 A;  2YOE A;  3JAD A;  4D01 A;  4EZ1 A;  5HEG A;  3IGQ A;  5AFN A;  4IL4 A;  3UQ7 A;  2YN6 A;  4QAC A;  4UXU A;  1UX2 A;  2BYR A;  5KZU A;  4ALX A;  4TNV A;  5JME A;  3TLT A;  3ZDH A;  3UU8 A;  4XHE A; 
#chains in the Genus database with same CATH topology
 2WNC A;  3SH1 A;  3RQW A;  2XZ6 A;  5AFM A;  2XQ7 A;  2BYP A;  2BR8 A;  4TWD A;  3SQ6 A;  4A98 A;  2YKS A;  4XK9 A;  5AFL A;  2BG9 C;  4NPP A;  4LMJ A;  5AFK A;  3LSV A;  5CFB A;  4ZK1 A;  2XYS A;  2XQ3 A;  3TLU A;  5HEU A;  3RHW A;  2W8G A;  5IUX A;  3P4W A;  4HFB A;  5BW2 A;  3T4M A;  4Z90 A;  5L4E A;  3TLS A;  4QAB A;  4ZRU A;  3SIO A;  2XQ5 A;  1UW6 A;  3EI0 A;  4HQP A;  3UU3 A;  4QAA A;  2XNT A;  4COF A;  4ILC A;  4UM3 P;  2YMD A;  3WTJ A;  4IRE A;  4A97 A;  1UV6 A;  3ZDG A;  5L47 A;  2BG9 E;  3WTH A;  2YME A;  2XNV A;  5KE4 A;  4IL9 A;  4QH5 A;  3U8L A;  4AFT A;  3ZKR A;  4AFH A;  3EAM A;  3PMZ A;  4ZJS A;  2QC1 B;  5HCM A;  4AFG A;  2Y57 A;  3WTI A;  4DBM A;  4UM3 S;  2X00 A;  3UUB A;  3C79 A;  2Y7Y A;  3WIP A;  3RQU A;  3RIF A;  1I9B A;  3UU6 A;  4ZJT A;  4X5T A;  2BG9 A;  4PIR A;  4UM3 A;  5HCJ A;  5FJV A;  5CO5 A;  2ZJU A;  3U8M A;  2BYQ A;  3WTO A;  4NZB A;  4UM1 A;  2BJ0 A;  5J0Z A;  2XYT A;  4HFC A;  2WNL A;  3JAE A;  3TLW A;  2W8F A;  3C84 A;  5AFM B;  2XQA A;  4ILA A;  2XQ8 A;  4WV9 A;  3U8J A;  3WTM A;  2PGZ A;  3UU4 A;  2XQ6 A;  2Y56 A;  2X00 D;  4ZR6 A;  5J5F A;  4TWF A;  4BQT A;  2XQ9 A;  4TNW A;  5HEO A;  2BYN A;  5SYO A;  4QH4 A;  3U8K A;  3UQ4 A;  2WN9 A;  3UU5 A;  4LMK A;  4HFE A;  3P50 A;  5J5G A;  4HFH A;  4B5D A;  4F8H A;  4HFD A;  3TLV A;  4ZZC A;  4QH1 A;  4HFI A;  4ILB A;  4FRR A;  4LML A;  5HEJ A;  5BRX A;  5AFH A;  2BG9 B;  4UY2 A;  5TVC A;  2Y54 A;  3WTN A;  4Z91 A;  3SQ9 A;  3EHZ A;  3RIA A;  2BR7 A;  2XZ5 A;  2XQ4 A;  3WTL A;  3WTK A;  5J5I A;  2C9T A;  2UZ6 A;  5AIN A;  3JAF A;  3RI5 A;  4BFQ A;  3PEO A;  3U8N A;  2VL0 A;  5LG3 A;  5HEH A;  2WNJ A;  5L4H A;  2WZY A;  4TWH A;  5AFJ A;  5J5H A;  5BP0 A;  2ZJV A;  4ZZB A;  3GUA A;  2BYS A;  5LXB A;  2XNU A;  2PH9 A;  4ZK4 A;  2Y58 A;  2YOE A;  3JAD A;  4D01 A;  4EZ1 A;  5HEG A;  3IGQ A;  5AFN A;  4IL4 A;  3UQ7 A;  2YN6 A;  4QAC A;  4UXU A;  1UX2 A;  2BYR A;  5KZU A;  4ALX A;  4TNV A;  5JME A;  3TLT A;  3ZDH A;  3UU8 A;  4XHE A; 
#chains in the Genus database with same CATH homology
 2WNC A;  3SH1 A;  3RQW A;  2XZ6 A;  5AFM A;  2XQ7 A;  2BYP A;  2BR8 A;  4TWD A;  3SQ6 A;  4A98 A;  2YKS A;  4XK9 A;  5AFL A;  2BG9 C;  4NPP A;  4LMJ A;  5AFK A;  3LSV A;  5CFB A;  4ZK1 A;  2XYS A;  2XQ3 A;  3TLU A;  5HEU A;  3RHW A;  2W8G A;  5IUX A;  3P4W A;  4HFB A;  5BW2 A;  3T4M A;  4Z90 A;  5L4E A;  3TLS A;  4QAB A;  4ZRU A;  3SIO A;  2XQ5 A;  1UW6 A;  3EI0 A;  4HQP A;  3UU3 A;  4QAA A;  2XNT A;  4COF A;  4ILC A;  4UM3 P;  2YMD A;  3WTJ A;  4IRE A;  4A97 A;  1UV6 A;  3ZDG A;  5L47 A;  2BG9 E;  3WTH A;  2YME A;  2XNV A;  5KE4 A;  4IL9 A;  4QH5 A;  3U8L A;  4AFT A;  3ZKR A;  4AFH A;  3EAM A;  3PMZ A;  4ZJS A;  2QC1 B;  5HCM A;  4AFG A;  2Y57 A;  3WTI A;  4DBM A;  4UM3 S;  2X00 A;  3UUB A;  3C79 A;  2Y7Y A;  3WIP A;  3RQU A;  3RIF A;  1I9B A;  3UU6 A;  4ZJT A;  4X5T A;  2BG9 A;  4PIR A;  4UM3 A;  5HCJ A;  5FJV A;  5CO5 A;  2ZJU A;  3U8M A;  2BYQ A;  3WTO A;  4NZB A;  4UM1 A;  2BJ0 A;  5J0Z A;  2XYT A;  4HFC A;  2WNL A;  3JAE A;  3TLW A;  2W8F A;  3C84 A;  5AFM B;  2XQA A;  4ILA A;  2XQ8 A;  4WV9 A;  3U8J A;  3WTM A;  2PGZ A;  3UU4 A;  2XQ6 A;  2Y56 A;  2X00 D;  4ZR6 A;  5J5F A;  4TWF A;  4BQT A;  2XQ9 A;  4TNW A;  5HEO A;  2BYN A;  5SYO A;  4QH4 A;  3U8K A;  3UQ4 A;  2WN9 A;  3UU5 A;  4LMK A;  4HFE A;  3P50 A;  5J5G A;  4HFH A;  4B5D A;  4F8H A;  4HFD A;  3TLV A;  4ZZC A;  4QH1 A;  4HFI A;  4ILB A;  4FRR A;  4LML A;  5HEJ A;  5BRX A;  5AFH A;  2BG9 B;  4UY2 A;  5TVC A;  2Y54 A;  3WTN A;  4Z91 A;  3SQ9 A;  3EHZ A;  3RIA A;  2BR7 A;  2XZ5 A;  2XQ4 A;  3WTL A;  3WTK A;  5J5I A;  2C9T A;  2UZ6 A;  5AIN A;  3JAF A;  3RI5 A;  4BFQ A;  3PEO A;  3U8N A;  2VL0 A;  5LG3 A;  5HEH A;  2WNJ A;  5L4H A;  2WZY A;  4TWH A;  5AFJ A;  5J5H A;  5BP0 A;  2ZJV A;  4ZZB A;  3GUA A;  2BYS A;  5LXB A;  2XNU A;  2PH9 A;  4ZK4 A;  2Y58 A;  2YOE A;  3JAD A;  4D01 A;  4EZ1 A;  5HEG A;  3IGQ A;  5AFN A;  4IL4 A;  3UQ7 A;  2YN6 A;  4QAC A;  4UXU A;  1UX2 A;  2BYR A;  5KZU A;  4ALX A;  4TNV A;  5JME A;  3TLT A;  3ZDH A;  3UU8 A;  4XHE A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2Y57A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations