2WNCA

Crystal structure of aplysia achbp in complex with tropisetron
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
215
structure length
215
Chain Sequence
DDDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERRAG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Receptor
source organism Aplysia californica
publication title Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal alpha7 nicotinic acetylcholine receptor.
pubmed doi rcsb
molecule keywords Soluble acetylcholine receptor
total genus 53
structure length 215
sequence length 215
chains with identical sequence B, C, D, E
ec nomenclature
pdb deposition date 2009-07-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 2wncA00
3UU4A 3IGQA 3EHZA 4HFHA 2XZ6A 5HEJA 2YMDA 2XQ3A 4ILCA 4NPPA 3ZDHA 3TLTA 2XQ9A 3P4WA 2WNCA 3U8LA 4AFTA 3PEOA 2Y58A 5KE4A 5J0ZA 3WTHA 3UQ7A 4UM3A 3WTMA 4ZZCA 2BG9E 2BYNA 3EI0A 3TLSA 5JMEA 5AFLA 4AFHA 2BR8A 5HCJA 4ZJSA 5J5GA 3SH1A 4AFGA 5AFNA 4ZJTA 5BRXA 4HFEA 3JAFA 5FJVA 3EAMA 4EZ1A 4QABA 3UU8A 3PMZA 2XYSA 5LXBA 4ZZBA 5AFMB 4HFCA 4Z90A 4BQTA 4TWFA 3RQUA 4DBMA 2BYQA 4ZR6A 2YN6A 4TNWA 2XNUA 2BG9A 4F8HA 4LMLA 3ZDGA 2YKSA 4BFQA 2BYSA 2QC1B 2BG9C 4HQPA 3WIPA 5BP0A 5J5HA 5L47A 2BJ0A 2Y54A 2YMEA 5AFMA 2XNTA 5J5FA 3JADA 3U8NA 2PH9A 5AFHA 2XNVA 4IREA 2WNJA 2Y56A 5LG3A 2ZJUA 4TNVA 2XQ5A 2XQAA 1UX2A 3GUAA 3WTOA 3UU3A 5SYOA 4UXUA 4WV9A 5AFJA 3ZKRA 4ILBA 2XQ7A 4QH1A 4LMJA 3SQ9A 4IL9A 3LSVA 3WTLA 4X5TA 5HEUA 3RIAA 3WTKA 5TVCA 2BYPA 4QH5A 3SQ6A 5L4HA 2BR7A 3RI5A 2WNLA 3C84A 4A98A 2XQ6A 4B5DA 2ZJVA 4HFDA 3RHWA 3RIFA 4A97A 5HEOA 4XHEA 5AINA 2W8FA 4PIRA 4ZRUA 5CFBA 4ILAA 5HCMA 3U8KA 2XQ4A 2W8GA 4QH4A 3TLUA 3U8MA 4UM1A 3UQ4A 2WZYA 4UY2A 3WTJA 4TWDA 4D01A 3TLVA 3T4MA 3C79A 4FRRA 5BW2A 4ZK4A 3RQWA 3SIOA 2BYRA 2C9TA 4TWHA 4XK9A 2WN9A 3WTIA 3TLWA 1UV6A 4LMKA 4COFA 5AFKA 1UW6A 4QAAA 4HFIA 3U8JA 4ZK1A 5IUXA 5CO5A 4HFBA 2XYTA 3JAEA 5J5IA 2BG9B 5KZUA 2XQ8A 5L4EA 3UU5A 5HEGA 2UZ6A 2Y7YA 4NZBA 4QACA 2X00D 2PGZA 4Z91A 5HEHA 3UU6A 4UM3S 2VL0A 2YOEA 3WTNA 3UUBA 2XZ5A 2X00A 3P50A 4IL4A 4UM3P 4ALXA 2Y57A 1I9BA
chains in the Genus database with same CATH superfamily
3UU4A 3IGQA 3EHZA 4HFHA 2XZ6A 5HEJA 2YMDA 2XQ3A 4ILCA 4NPPA 3ZDHA 3TLTA 2XQ9A 3P4WA 2WNCA 3U8LA 4AFTA 3PEOA 2Y58A 5KE4A 5J0ZA 3WTHA 3UQ7A 4UM3A 3WTMA 4ZZCA 2BG9E 2BYNA 3EI0A 3TLSA 5JMEA 5AFLA 4AFHA 2BR8A 5HCJA 4ZJSA 5J5GA 3SH1A 4AFGA 5AFNA 4ZJTA 5BRXA 4HFEA 3JAFA 5FJVA 3EAMA 4EZ1A 4QABA 3UU8A 3PMZA 2XYSA 5LXBA 4ZZBA 5AFMB 4HFCA 4Z90A 4BQTA 4TWFA 3RQUA 4DBMA 2BYQA 4ZR6A 2YN6A 4TNWA 2XNUA 2BG9A 4F8HA 4LMLA 3ZDGA 2YKSA 4BFQA 2BYSA 2QC1B 2BG9C 4HQPA 3WIPA 5BP0A 5J5HA 5L47A 2BJ0A 2Y54A 2YMEA 5AFMA 2XNTA 5J5FA 3JADA 3U8NA 2PH9A 5AFHA 2XNVA 4IREA 2WNJA 2Y56A 5LG3A 2ZJUA 4TNVA 2XQ5A 2XQAA 1UX2A 3GUAA 3WTOA 3UU3A 5SYOA 4UXUA 4WV9A 5AFJA 3ZKRA 4ILBA 2XQ7A 4QH1A 4LMJA 3SQ9A 4IL9A 3LSVA 3WTLA 4X5TA 5HEUA 3RIAA 3WTKA 5TVCA 2BYPA 4QH5A 3SQ6A 5L4HA 2BR7A 3RI5A 2WNLA 3C84A 4A98A 2XQ6A 4B5DA 2ZJVA 4HFDA 3RHWA 3RIFA 4A97A 5HEOA 4XHEA 5AINA 2W8FA 4PIRA 4ZRUA 5CFBA 4ILAA 5HCMA 3U8KA 2XQ4A 2W8GA 4QH4A 3TLUA 3U8MA 4UM1A 3UQ4A 2WZYA 4UY2A 3WTJA 4TWDA 4D01A 3TLVA 3T4MA 3C79A 4FRRA 5BW2A 4ZK4A 3RQWA 3SIOA 2BYRA 2C9TA 4TWHA 4XK9A 2WN9A 3WTIA 3TLWA 1UV6A 4LMKA 4COFA 5AFKA 1UW6A 4QAAA 4HFIA 3U8JA 4ZK1A 5IUXA 5CO5A 4HFBA 2XYTA 3JAEA 5J5IA 2BG9B 5KZUA 2XQ8A 5L4EA 3UU5A 5HEGA 2UZ6A 2Y7YA 4NZBA 4QACA 2X00D 2PGZA 4Z91A 5HEHA 3UU6A 4UM3S 2VL0A 2YOEA 3WTNA 3UUBA 2XZ5A 2X00A 3P50A 4IL4A 4UM3P 4ALXA 2Y57A 1I9BA
chains in the Genus database with same CATH topology
3UU4A 3IGQA 3EHZA 4HFHA 2XZ6A 5HEJA 2YMDA 2XQ3A 4ILCA 4NPPA 3ZDHA 3TLTA 2XQ9A 3P4WA 2WNCA 3U8LA 4AFTA 3PEOA 2Y58A 5KE4A 5J0ZA 3WTHA 3UQ7A 4UM3A 3WTMA 4ZZCA 2BG9E 2BYNA 3EI0A 3TLSA 5JMEA 5AFLA 4AFHA 2BR8A 5HCJA 4ZJSA 5J5GA 3SH1A 4AFGA 5AFNA 4ZJTA 5BRXA 4HFEA 3JAFA 5FJVA 3EAMA 4EZ1A 4QABA 3UU8A 3PMZA 2XYSA 5LXBA 4ZZBA 5AFMB 4HFCA 4Z90A 4BQTA 4TWFA 3RQUA 4DBMA 2BYQA 4ZR6A 2YN6A 4TNWA 2XNUA 2BG9A 4F8HA 4LMLA 3ZDGA 2YKSA 4BFQA 2BYSA 2QC1B 2BG9C 4HQPA 3WIPA 5BP0A 5J5HA 5L47A 2BJ0A 2Y54A 2YMEA 5AFMA 2XNTA 5J5FA 3JADA 3U8NA 2PH9A 5AFHA 2XNVA 4IREA 2WNJA 2Y56A 5LG3A 2ZJUA 4TNVA 2XQ5A 2XQAA 1UX2A 3GUAA 3WTOA 3UU3A 5SYOA 4UXUA 4WV9A 5AFJA 3ZKRA 4ILBA 2XQ7A 4QH1A 4LMJA 3SQ9A 4IL9A 3LSVA 3WTLA 4X5TA 5HEUA 3RIAA 3WTKA 5TVCA 2BYPA 4QH5A 3SQ6A 5L4HA 2BR7A 3RI5A 2WNLA 3C84A 4A98A 2XQ6A 4B5DA 2ZJVA 4HFDA 3RHWA 3RIFA 4A97A 5HEOA 4XHEA 5AINA 2W8FA 4PIRA 4ZRUA 5CFBA 4ILAA 5HCMA 3U8KA 2XQ4A 2W8GA 4QH4A 3TLUA 3U8MA 4UM1A 3UQ4A 2WZYA 4UY2A 3WTJA 4TWDA 4D01A 3TLVA 3T4MA 3C79A 4FRRA 5BW2A 4ZK4A 3RQWA 3SIOA 2BYRA 2C9TA 4TWHA 4XK9A 2WN9A 3WTIA 3TLWA 1UV6A 4LMKA 4COFA 5AFKA 1UW6A 4QAAA 4HFIA 3U8JA 4ZK1A 5IUXA 5CO5A 4HFBA 2XYTA 3JAEA 5J5IA 2BG9B 5KZUA 2XQ8A 5L4EA 3UU5A 5HEGA 2UZ6A 2Y7YA 4NZBA 4QACA 2X00D 2PGZA 4Z91A 5HEHA 3UU6A 4UM3S 2VL0A 2YOEA 3WTNA 3UUBA 2XZ5A 2X00A 3P50A 4IL4A 4UM3P 4ALXA 2Y57A 1I9BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3UU4 A;  3IGQ A;  3EHZ A;  4HFH A;  2XZ6 A;  5HEJ A;  2YMD A;  2XQ3 A;  4ILC A;  4NPP A;  3ZDH A;  3TLT A;  2XQ9 A;  3P4W A;  2WNC A;  3U8L A;  4AFT A;  3PEO A;  2Y58 A;  5KE4 A;  5J0Z A;  3WTH A;  3UQ7 A;  4UM3 A;  3WTM A;  4ZZC A;  2BG9 E;  2BYN A;  3EI0 A;  3TLS A;  5JME A;  5AFL A;  4AFH A;  2BR8 A;  5HCJ A;  4ZJS A;  5J5G A;  3SH1 A;  4AFG A;  5AFN A;  4ZJT A;  5BRX A;  4HFE A;  3JAF A;  5FJV A;  3EAM A;  4EZ1 A;  4QAB A;  3UU8 A;  3PMZ A;  2XYS A;  5LXB A;  4ZZB A;  5AFM B;  4HFC A;  4Z90 A;  4BQT A;  4TWF A;  3RQU A;  4DBM A;  2BYQ A;  4ZR6 A;  2YN6 A;  4TNW A;  2XNU A;  2BG9 A;  4F8H A;  4LML A;  3ZDG A;  2YKS A;  4BFQ A;  2BYS A;  2QC1 B;  2BG9 C;  4HQP A;  3WIP A;  5BP0 A;  5J5H A;  5L47 A;  2BJ0 A;  2Y54 A;  2YME A;  5AFM A;  2XNT A;  5J5F A;  3JAD A;  3U8N A;  2PH9 A;  5AFH A;  2XNV A;  4IRE A;  2WNJ A;  2Y56 A;  5LG3 A;  2ZJU A;  4TNV A;  2XQ5 A;  2XQA A;  1UX2 A;  3GUA A;  3WTO A;  3UU3 A;  5SYO A;  4UXU A;  4WV9 A;  5AFJ A;  3ZKR A;  4ILB A;  2XQ7 A;  4QH1 A;  4LMJ A;  3SQ9 A;  4IL9 A;  3LSV A;  3WTL A;  4X5T A;  5HEU A;  3RIA A;  3WTK A;  5TVC A;  2BYP A;  4QH5 A;  3SQ6 A;  5L4H A;  2BR7 A;  3RI5 A;  2WNL A;  3C84 A;  4A98 A;  2XQ6 A;  4B5D A;  2ZJV A;  4HFD A;  3RHW A;  3RIF A;  4A97 A;  5HEO A;  4XHE A;  5AIN A;  2W8F A;  4PIR A;  4ZRU A;  5CFB A;  4ILA A;  5HCM A;  3U8K A;  2XQ4 A;  2W8G A;  4QH4 A;  3TLU A;  3U8M A;  4UM1 A;  3UQ4 A;  2WZY A;  4UY2 A;  3WTJ A;  4TWD A;  4D01 A;  3TLV A;  3T4M A;  3C79 A;  4FRR A;  5BW2 A;  4ZK4 A;  3RQW A;  3SIO A;  2BYR A;  2C9T A;  4TWH A;  4XK9 A;  2WN9 A;  3WTI A;  3TLW A;  1UV6 A;  4LMK A;  4COF A;  5AFK A;  1UW6 A;  4QAA A;  4HFI A;  3U8J A;  4ZK1 A;  5IUX A;  5CO5 A;  4HFB A;  2XYT A;  3JAE A;  5J5I A;  2BG9 B;  5KZU A;  2XQ8 A;  5L4E A;  3UU5 A;  5HEG A;  2UZ6 A;  2Y7Y A;  4NZB A;  4QAC A;  2X00 D;  2PGZ A;  4Z91 A;  5HEH A;  3UU6 A;  4UM3 S;  2VL0 A;  2YOE A;  3WTN A;  3UUB A;  2XZ5 A;  2X00 A;  3P50 A;  4IL4 A;  4UM3 P;  4ALX A;  2Y57 A;  1I9B A; 
#chains in the Genus database with same CATH topology
 3UU4 A;  3IGQ A;  3EHZ A;  4HFH A;  2XZ6 A;  5HEJ A;  2YMD A;  2XQ3 A;  4ILC A;  4NPP A;  3ZDH A;  3TLT A;  2XQ9 A;  3P4W A;  2WNC A;  3U8L A;  4AFT A;  3PEO A;  2Y58 A;  5KE4 A;  5J0Z A;  3WTH A;  3UQ7 A;  4UM3 A;  3WTM A;  4ZZC A;  2BG9 E;  2BYN A;  3EI0 A;  3TLS A;  5JME A;  5AFL A;  4AFH A;  2BR8 A;  5HCJ A;  4ZJS A;  5J5G A;  3SH1 A;  4AFG A;  5AFN A;  4ZJT A;  5BRX A;  4HFE A;  3JAF A;  5FJV A;  3EAM A;  4EZ1 A;  4QAB A;  3UU8 A;  3PMZ A;  2XYS A;  5LXB A;  4ZZB A;  5AFM B;  4HFC A;  4Z90 A;  4BQT A;  4TWF A;  3RQU A;  4DBM A;  2BYQ A;  4ZR6 A;  2YN6 A;  4TNW A;  2XNU A;  2BG9 A;  4F8H A;  4LML A;  3ZDG A;  2YKS A;  4BFQ A;  2BYS A;  2QC1 B;  2BG9 C;  4HQP A;  3WIP A;  5BP0 A;  5J5H A;  5L47 A;  2BJ0 A;  2Y54 A;  2YME A;  5AFM A;  2XNT A;  5J5F A;  3JAD A;  3U8N A;  2PH9 A;  5AFH A;  2XNV A;  4IRE A;  2WNJ A;  2Y56 A;  5LG3 A;  2ZJU A;  4TNV A;  2XQ5 A;  2XQA A;  1UX2 A;  3GUA A;  3WTO A;  3UU3 A;  5SYO A;  4UXU A;  4WV9 A;  5AFJ A;  3ZKR A;  4ILB A;  2XQ7 A;  4QH1 A;  4LMJ A;  3SQ9 A;  4IL9 A;  3LSV A;  3WTL A;  4X5T A;  5HEU A;  3RIA A;  3WTK A;  5TVC A;  2BYP A;  4QH5 A;  3SQ6 A;  5L4H A;  2BR7 A;  3RI5 A;  2WNL A;  3C84 A;  4A98 A;  2XQ6 A;  4B5D A;  2ZJV A;  4HFD A;  3RHW A;  3RIF A;  4A97 A;  5HEO A;  4XHE A;  5AIN A;  2W8F A;  4PIR A;  4ZRU A;  5CFB A;  4ILA A;  5HCM A;  3U8K A;  2XQ4 A;  2W8G A;  4QH4 A;  3TLU A;  3U8M A;  4UM1 A;  3UQ4 A;  2WZY A;  4UY2 A;  3WTJ A;  4TWD A;  4D01 A;  3TLV A;  3T4M A;  3C79 A;  4FRR A;  5BW2 A;  4ZK4 A;  3RQW A;  3SIO A;  2BYR A;  2C9T A;  4TWH A;  4XK9 A;  2WN9 A;  3WTI A;  3TLW A;  1UV6 A;  4LMK A;  4COF A;  5AFK A;  1UW6 A;  4QAA A;  4HFI A;  3U8J A;  4ZK1 A;  5IUX A;  5CO5 A;  4HFB A;  2XYT A;  3JAE A;  5J5I A;  2BG9 B;  5KZU A;  2XQ8 A;  5L4E A;  3UU5 A;  5HEG A;  2UZ6 A;  2Y7Y A;  4NZB A;  4QAC A;  2X00 D;  2PGZ A;  4Z91 A;  5HEH A;  3UU6 A;  4UM3 S;  2VL0 A;  2YOE A;  3WTN A;  3UUB A;  2XZ5 A;  2X00 A;  3P50 A;  4IL4 A;  4UM3 P;  4ALX A;  2Y57 A;  1I9B A; 
#chains in the Genus database with same CATH homology
 3UU4 A;  3IGQ A;  3EHZ A;  4HFH A;  2XZ6 A;  5HEJ A;  2YMD A;  2XQ3 A;  4ILC A;  4NPP A;  3ZDH A;  3TLT A;  2XQ9 A;  3P4W A;  2WNC A;  3U8L A;  4AFT A;  3PEO A;  2Y58 A;  5KE4 A;  5J0Z A;  3WTH A;  3UQ7 A;  4UM3 A;  3WTM A;  4ZZC A;  2BG9 E;  2BYN A;  3EI0 A;  3TLS A;  5JME A;  5AFL A;  4AFH A;  2BR8 A;  5HCJ A;  4ZJS A;  5J5G A;  3SH1 A;  4AFG A;  5AFN A;  4ZJT A;  5BRX A;  4HFE A;  3JAF A;  5FJV A;  3EAM A;  4EZ1 A;  4QAB A;  3UU8 A;  3PMZ A;  2XYS A;  5LXB A;  4ZZB A;  5AFM B;  4HFC A;  4Z90 A;  4BQT A;  4TWF A;  3RQU A;  4DBM A;  2BYQ A;  4ZR6 A;  2YN6 A;  4TNW A;  2XNU A;  2BG9 A;  4F8H A;  4LML A;  3ZDG A;  2YKS A;  4BFQ A;  2BYS A;  2QC1 B;  2BG9 C;  4HQP A;  3WIP A;  5BP0 A;  5J5H A;  5L47 A;  2BJ0 A;  2Y54 A;  2YME A;  5AFM A;  2XNT A;  5J5F A;  3JAD A;  3U8N A;  2PH9 A;  5AFH A;  2XNV A;  4IRE A;  2WNJ A;  2Y56 A;  5LG3 A;  2ZJU A;  4TNV A;  2XQ5 A;  2XQA A;  1UX2 A;  3GUA A;  3WTO A;  3UU3 A;  5SYO A;  4UXU A;  4WV9 A;  5AFJ A;  3ZKR A;  4ILB A;  2XQ7 A;  4QH1 A;  4LMJ A;  3SQ9 A;  4IL9 A;  3LSV A;  3WTL A;  4X5T A;  5HEU A;  3RIA A;  3WTK A;  5TVC A;  2BYP A;  4QH5 A;  3SQ6 A;  5L4H A;  2BR7 A;  3RI5 A;  2WNL A;  3C84 A;  4A98 A;  2XQ6 A;  4B5D A;  2ZJV A;  4HFD A;  3RHW A;  3RIF A;  4A97 A;  5HEO A;  4XHE A;  5AIN A;  2W8F A;  4PIR A;  4ZRU A;  5CFB A;  4ILA A;  5HCM A;  3U8K A;  2XQ4 A;  2W8G A;  4QH4 A;  3TLU A;  3U8M A;  4UM1 A;  3UQ4 A;  2WZY A;  4UY2 A;  3WTJ A;  4TWD A;  4D01 A;  3TLV A;  3T4M A;  3C79 A;  4FRR A;  5BW2 A;  4ZK4 A;  3RQW A;  3SIO A;  2BYR A;  2C9T A;  4TWH A;  4XK9 A;  2WN9 A;  3WTI A;  3TLW A;  1UV6 A;  4LMK A;  4COF A;  5AFK A;  1UW6 A;  4QAA A;  4HFI A;  3U8J A;  4ZK1 A;  5IUX A;  5CO5 A;  4HFB A;  2XYT A;  3JAE A;  5J5I A;  2BG9 B;  5KZU A;  2XQ8 A;  5L4E A;  3UU5 A;  5HEG A;  2UZ6 A;  2Y7Y A;  4NZB A;  4QAC A;  2X00 D;  2PGZ A;  4Z91 A;  5HEH A;  3UU6 A;  4UM3 S;  2VL0 A;  2YOE A;  3WTN A;  3UUB A;  2XZ5 A;  2X00 A;  3P50 A;  4IL4 A;  4UM3 P;  4ALX A;  2Y57 A;  1I9B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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