2Y54A

Fragment growing induces conformational changes in acetylcholine- binding protein: a structural and thermodynamic analysis - (fragment 1)
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
205
structure length
205
Chain Sequence
QANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKVDSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGVTCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Receptor
source organism Aplysia californica
publication title Fragment Growing Induces Conformational Changes in Acetylcholine-Binding Protein: A Structural and Thermodynamic Analysis.
pubmed doi rcsb
molecule keywords SOLUBLE ACETYLCHOLINE RECEPTOR
total genus 43
structure length 205
sequence length 205
chains with identical sequence B, C, D, E
ec nomenclature
pdb deposition date 2011-01-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 2y54A00
2ZJVA 2W8GA 3PMZA 5BP0A 4UM3P 2BYPA 2XNVA 3UQ4A 3UU3A 3WTNA 3EI0A 2BYSA 4Z90A 5JMEA 4UM1A 4HFDA 2VL0A 5FJVA 4TWDA 3TLSA 4Z91A 1UW6A 4QABA 5AFHA 2BJ0A 5AINA 4HFEA 4X5TA 4D01A 3WTJA 3WTMA 4NZBA 3WIPA 4HQPA 2XQ3A 1UX2A 4B5DA 2XQ7A 4WV9A 2Y58A 3ZDHA 4A97A 2PGZA 4ZZBA 4F8HA 2XZ6A 4XK9A 3SQ6A 3WTHA 4AFHA 5AFKA 4ZR6A 3TLWA 4EZ1A 1I9BA 2PH9A 4LMLA 3WTLA 2BG9E 2BG9A 4BFQA 3ZDGA 4BQTA 5HEGA 5IUXA 5AFLA 5HEHA 2Y54A 3WTOA 2BG9B 2YMEA 4TWFA 2XNUA 3RHWA 2X00A 4AFTA 2WN9A 2Y56A 4ILCA 2X00D 4TWHA 4UM3A 3SIOA 3UU5A 4DBMA 2YOEA 3JAFA 4AFGA 4FRRA 5HEUA 2UZ6A 2YN6A 2BYNA 2WNLA 4ZJTA 5L47A 4ILAA 2YKSA 3PEOA 2QC1B 5HCMA 5CFBA 4PIRA 2XYSA 4HFCA 3EHZA 3C79A 5TVCA 5L4EA 5CO5A 5J5GA 4NPPA 4A98A 3WTIA 3U8LA 2WNCA 3U8KA 5KZUA 5AFJA 5HEOA 2XNTA 3GUAA 3SH1A 2BYQA 3C84A 4IREA 5J0ZA 4LMKA 5J5HA 2XQ8A 2ZJUA 3IGQA 3P50A 2XQ4A 3JADA 1UV6A 4IL4A 4TNWA 2Y7YA 4UM3S 2C9TA 5SYOA 4QH4A 4ZK4A 3P4WA 3WTKA 3U8MA 5HEJA 5L4HA 3RI5A 2W8FA 4HFHA 2XYTA 5HCJA 3T4MA 3UU8A 4HFIA 2XQAA 4QH1A 4ILBA 4HFBA 4UXUA 2BR8A 4COFA 5LXBA 2BR7A 4QACA 5J5FA 3UU4A 5AFMA 2WNJA 4ZK1A 5BW2A 4UY2A 3EAMA 3RIFA 5AFMB 3UQ7A 2BG9C 3RIAA 2XQ5A 4ZRUA 3TLVA 5AFNA 3UU6A 2XZ5A 4XHEA 3U8JA 4ZJSA 2YMDA 2XQ6A 2BYRA 4TNVA 5LG3A 3RQWA 3TLUA 3UUBA 3U8NA 5BRXA 4QAAA 2Y57A 2XQ9A 5J5IA 4LMJA 3ZKRA 3TLTA 4QH5A 3JAEA 5KE4A 3SQ9A 3LSVA 3RQUA 4IL9A 4ALXA 4ZZCA 2WZYA
chains in the Genus database with same CATH superfamily
2ZJVA 2W8GA 3PMZA 5BP0A 4UM3P 2BYPA 2XNVA 3UQ4A 3UU3A 3WTNA 3EI0A 2BYSA 4Z90A 5JMEA 4UM1A 4HFDA 2VL0A 5FJVA 4TWDA 3TLSA 4Z91A 1UW6A 4QABA 5AFHA 2BJ0A 5AINA 4HFEA 4X5TA 4D01A 3WTJA 3WTMA 4NZBA 3WIPA 4HQPA 2XQ3A 1UX2A 4B5DA 2XQ7A 4WV9A 2Y58A 3ZDHA 4A97A 2PGZA 4ZZBA 4F8HA 2XZ6A 4XK9A 3SQ6A 3WTHA 4AFHA 5AFKA 4ZR6A 3TLWA 4EZ1A 1I9BA 2PH9A 4LMLA 3WTLA 2BG9E 2BG9A 4BFQA 3ZDGA 4BQTA 5HEGA 5IUXA 5AFLA 5HEHA 2Y54A 3WTOA 2BG9B 2YMEA 4TWFA 2XNUA 3RHWA 2X00A 4AFTA 2WN9A 2Y56A 4ILCA 2X00D 4TWHA 4UM3A 3SIOA 3UU5A 4DBMA 2YOEA 3JAFA 4AFGA 4FRRA 5HEUA 2UZ6A 2YN6A 2BYNA 2WNLA 4ZJTA 5L47A 4ILAA 2YKSA 3PEOA 2QC1B 5HCMA 5CFBA 4PIRA 2XYSA 4HFCA 3EHZA 3C79A 5TVCA 5L4EA 5CO5A 5J5GA 4NPPA 4A98A 3WTIA 3U8LA 2WNCA 3U8KA 5KZUA 5AFJA 5HEOA 2XNTA 3GUAA 3SH1A 2BYQA 3C84A 4IREA 5J0ZA 4LMKA 5J5HA 2XQ8A 2ZJUA 3IGQA 3P50A 2XQ4A 3JADA 1UV6A 4IL4A 4TNWA 2Y7YA 4UM3S 2C9TA 5SYOA 4QH4A 4ZK4A 3P4WA 3WTKA 3U8MA 5HEJA 5L4HA 3RI5A 2W8FA 4HFHA 2XYTA 5HCJA 3T4MA 3UU8A 4HFIA 2XQAA 4QH1A 4ILBA 4HFBA 4UXUA 2BR8A 4COFA 5LXBA 2BR7A 4QACA 5J5FA 3UU4A 5AFMA 2WNJA 4ZK1A 5BW2A 4UY2A 3EAMA 3RIFA 5AFMB 3UQ7A 2BG9C 3RIAA 2XQ5A 4ZRUA 3TLVA 5AFNA 3UU6A 2XZ5A 4XHEA 3U8JA 4ZJSA 2YMDA 2XQ6A 2BYRA 4TNVA 5LG3A 3RQWA 3TLUA 3UUBA 3U8NA 5BRXA 4QAAA 2Y57A 2XQ9A 5J5IA 4LMJA 3ZKRA 3TLTA 4QH5A 3JAEA 5KE4A 3SQ9A 3LSVA 3RQUA 4IL9A 4ALXA 4ZZCA 2WZYA
chains in the Genus database with same CATH topology
2ZJVA 2W8GA 3PMZA 5BP0A 4UM3P 2BYPA 2XNVA 3UQ4A 3UU3A 3WTNA 3EI0A 2BYSA 4Z90A 5JMEA 4UM1A 4HFDA 2VL0A 5FJVA 4TWDA 3TLSA 4Z91A 1UW6A 4QABA 5AFHA 2BJ0A 5AINA 4HFEA 4X5TA 4D01A 3WTJA 3WTMA 4NZBA 3WIPA 4HQPA 2XQ3A 1UX2A 4B5DA 2XQ7A 4WV9A 2Y58A 3ZDHA 4A97A 2PGZA 4ZZBA 4F8HA 2XZ6A 4XK9A 3SQ6A 3WTHA 4AFHA 5AFKA 4ZR6A 3TLWA 4EZ1A 1I9BA 2PH9A 4LMLA 3WTLA 2BG9E 2BG9A 4BFQA 3ZDGA 4BQTA 5HEGA 5IUXA 5AFLA 5HEHA 2Y54A 3WTOA 2BG9B 2YMEA 4TWFA 2XNUA 3RHWA 2X00A 4AFTA 2WN9A 2Y56A 4ILCA 2X00D 4TWHA 4UM3A 3SIOA 3UU5A 4DBMA 2YOEA 3JAFA 4AFGA 4FRRA 5HEUA 2UZ6A 2YN6A 2BYNA 2WNLA 4ZJTA 5L47A 4ILAA 2YKSA 3PEOA 2QC1B 5HCMA 5CFBA 4PIRA 2XYSA 4HFCA 3EHZA 3C79A 5TVCA 5L4EA 5CO5A 5J5GA 4NPPA 4A98A 3WTIA 3U8LA 2WNCA 3U8KA 5KZUA 5AFJA 5HEOA 2XNTA 3GUAA 3SH1A 2BYQA 3C84A 4IREA 5J0ZA 4LMKA 5J5HA 2XQ8A 2ZJUA 3IGQA 3P50A 2XQ4A 3JADA 1UV6A 4IL4A 4TNWA 2Y7YA 4UM3S 2C9TA 5SYOA 4QH4A 4ZK4A 3P4WA 3WTKA 3U8MA 5HEJA 5L4HA 3RI5A 2W8FA 4HFHA 2XYTA 5HCJA 3T4MA 3UU8A 4HFIA 2XQAA 4QH1A 4ILBA 4HFBA 4UXUA 2BR8A 4COFA 5LXBA 2BR7A 4QACA 5J5FA 3UU4A 5AFMA 2WNJA 4ZK1A 5BW2A 4UY2A 3EAMA 3RIFA 5AFMB 3UQ7A 2BG9C 3RIAA 2XQ5A 4ZRUA 3TLVA 5AFNA 3UU6A 2XZ5A 4XHEA 3U8JA 4ZJSA 2YMDA 2XQ6A 2BYRA 4TNVA 5LG3A 3RQWA 3TLUA 3UUBA 3U8NA 5BRXA 4QAAA 2Y57A 2XQ9A 5J5IA 4LMJA 3ZKRA 3TLTA 4QH5A 3JAEA 5KE4A 3SQ9A 3LSVA 3RQUA 4IL9A 4ALXA 4ZZCA 2WZYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZJV A;  2W8G A;  3PMZ A;  5BP0 A;  4UM3 P;  2BYP A;  2XNV A;  3UQ4 A;  3UU3 A;  3WTN A;  3EI0 A;  2BYS A;  4Z90 A;  5JME A;  4UM1 A;  4HFD A;  2VL0 A;  5FJV A;  4TWD A;  3TLS A;  4Z91 A;  1UW6 A;  4QAB A;  5AFH A;  2BJ0 A;  5AIN A;  4HFE A;  4X5T A;  4D01 A;  3WTJ A;  3WTM A;  4NZB A;  3WIP A;  4HQP A;  2XQ3 A;  1UX2 A;  4B5D A;  2XQ7 A;  4WV9 A;  2Y58 A;  3ZDH A;  4A97 A;  2PGZ A;  4ZZB A;  4F8H A;  2XZ6 A;  4XK9 A;  3SQ6 A;  3WTH A;  4AFH A;  5AFK A;  4ZR6 A;  3TLW A;  4EZ1 A;  1I9B A;  2PH9 A;  4LML A;  3WTL A;  2BG9 E;  2BG9 A;  4BFQ A;  3ZDG A;  4BQT A;  5HEG A;  5IUX A;  5AFL A;  5HEH A;  2Y54 A;  3WTO A;  2BG9 B;  2YME A;  4TWF A;  2XNU A;  3RHW A;  2X00 A;  4AFT A;  2WN9 A;  2Y56 A;  4ILC A;  2X00 D;  4TWH A;  4UM3 A;  3SIO A;  3UU5 A;  4DBM A;  2YOE A;  3JAF A;  4AFG A;  4FRR A;  5HEU A;  2UZ6 A;  2YN6 A;  2BYN A;  2WNL A;  4ZJT A;  5L47 A;  4ILA A;  2YKS A;  3PEO A;  2QC1 B;  5HCM A;  5CFB A;  4PIR A;  2XYS A;  4HFC A;  3EHZ A;  3C79 A;  5TVC A;  5L4E A;  5CO5 A;  5J5G A;  4NPP A;  4A98 A;  3WTI A;  3U8L A;  2WNC A;  3U8K A;  5KZU A;  5AFJ A;  5HEO A;  2XNT A;  3GUA A;  3SH1 A;  2BYQ A;  3C84 A;  4IRE A;  5J0Z A;  4LMK A;  5J5H A;  2XQ8 A;  2ZJU A;  3IGQ A;  3P50 A;  2XQ4 A;  3JAD A;  1UV6 A;  4IL4 A;  4TNW A;  2Y7Y A;  4UM3 S;  2C9T A;  5SYO A;  4QH4 A;  4ZK4 A;  3P4W A;  3WTK A;  3U8M A;  5HEJ A;  5L4H A;  3RI5 A;  2W8F A;  4HFH A;  2XYT A;  5HCJ A;  3T4M A;  3UU8 A;  4HFI A;  2XQA A;  4QH1 A;  4ILB A;  4HFB A;  4UXU A;  2BR8 A;  4COF A;  5LXB A;  2BR7 A;  4QAC A;  5J5F A;  3UU4 A;  5AFM A;  2WNJ A;  4ZK1 A;  5BW2 A;  4UY2 A;  3EAM A;  3RIF A;  5AFM B;  3UQ7 A;  2BG9 C;  3RIA A;  2XQ5 A;  4ZRU A;  3TLV A;  5AFN A;  3UU6 A;  2XZ5 A;  4XHE A;  3U8J A;  4ZJS A;  2YMD A;  2XQ6 A;  2BYR A;  4TNV A;  5LG3 A;  3RQW A;  3TLU A;  3UUB A;  3U8N A;  5BRX A;  4QAA A;  2Y57 A;  2XQ9 A;  5J5I A;  4LMJ A;  3ZKR A;  3TLT A;  4QH5 A;  3JAE A;  5KE4 A;  3SQ9 A;  3LSV A;  3RQU A;  4IL9 A;  4ALX A;  4ZZC A;  2WZY A; 
#chains in the Genus database with same CATH topology
 2ZJV A;  2W8G A;  3PMZ A;  5BP0 A;  4UM3 P;  2BYP A;  2XNV A;  3UQ4 A;  3UU3 A;  3WTN A;  3EI0 A;  2BYS A;  4Z90 A;  5JME A;  4UM1 A;  4HFD A;  2VL0 A;  5FJV A;  4TWD A;  3TLS A;  4Z91 A;  1UW6 A;  4QAB A;  5AFH A;  2BJ0 A;  5AIN A;  4HFE A;  4X5T A;  4D01 A;  3WTJ A;  3WTM A;  4NZB A;  3WIP A;  4HQP A;  2XQ3 A;  1UX2 A;  4B5D A;  2XQ7 A;  4WV9 A;  2Y58 A;  3ZDH A;  4A97 A;  2PGZ A;  4ZZB A;  4F8H A;  2XZ6 A;  4XK9 A;  3SQ6 A;  3WTH A;  4AFH A;  5AFK A;  4ZR6 A;  3TLW A;  4EZ1 A;  1I9B A;  2PH9 A;  4LML A;  3WTL A;  2BG9 E;  2BG9 A;  4BFQ A;  3ZDG A;  4BQT A;  5HEG A;  5IUX A;  5AFL A;  5HEH A;  2Y54 A;  3WTO A;  2BG9 B;  2YME A;  4TWF A;  2XNU A;  3RHW A;  2X00 A;  4AFT A;  2WN9 A;  2Y56 A;  4ILC A;  2X00 D;  4TWH A;  4UM3 A;  3SIO A;  3UU5 A;  4DBM A;  2YOE A;  3JAF A;  4AFG A;  4FRR A;  5HEU A;  2UZ6 A;  2YN6 A;  2BYN A;  2WNL A;  4ZJT A;  5L47 A;  4ILA A;  2YKS A;  3PEO A;  2QC1 B;  5HCM A;  5CFB A;  4PIR A;  2XYS A;  4HFC A;  3EHZ A;  3C79 A;  5TVC A;  5L4E A;  5CO5 A;  5J5G A;  4NPP A;  4A98 A;  3WTI A;  3U8L A;  2WNC A;  3U8K A;  5KZU A;  5AFJ A;  5HEO A;  2XNT A;  3GUA A;  3SH1 A;  2BYQ A;  3C84 A;  4IRE A;  5J0Z A;  4LMK A;  5J5H A;  2XQ8 A;  2ZJU A;  3IGQ A;  3P50 A;  2XQ4 A;  3JAD A;  1UV6 A;  4IL4 A;  4TNW A;  2Y7Y A;  4UM3 S;  2C9T A;  5SYO A;  4QH4 A;  4ZK4 A;  3P4W A;  3WTK A;  3U8M A;  5HEJ A;  5L4H A;  3RI5 A;  2W8F A;  4HFH A;  2XYT A;  5HCJ A;  3T4M A;  3UU8 A;  4HFI A;  2XQA A;  4QH1 A;  4ILB A;  4HFB A;  4UXU A;  2BR8 A;  4COF A;  5LXB A;  2BR7 A;  4QAC A;  5J5F A;  3UU4 A;  5AFM A;  2WNJ A;  4ZK1 A;  5BW2 A;  4UY2 A;  3EAM A;  3RIF A;  5AFM B;  3UQ7 A;  2BG9 C;  3RIA A;  2XQ5 A;  4ZRU A;  3TLV A;  5AFN A;  3UU6 A;  2XZ5 A;  4XHE A;  3U8J A;  4ZJS A;  2YMD A;  2XQ6 A;  2BYR A;  4TNV A;  5LG3 A;  3RQW A;  3TLU A;  3UUB A;  3U8N A;  5BRX A;  4QAA A;  2Y57 A;  2XQ9 A;  5J5I A;  4LMJ A;  3ZKR A;  3TLT A;  4QH5 A;  3JAE A;  5KE4 A;  3SQ9 A;  3LSV A;  3RQU A;  4IL9 A;  4ALX A;  4ZZC A;  2WZY A; 
#chains in the Genus database with same CATH homology
 2ZJV A;  2W8G A;  3PMZ A;  5BP0 A;  4UM3 P;  2BYP A;  2XNV A;  3UQ4 A;  3UU3 A;  3WTN A;  3EI0 A;  2BYS A;  4Z90 A;  5JME A;  4UM1 A;  4HFD A;  2VL0 A;  5FJV A;  4TWD A;  3TLS A;  4Z91 A;  1UW6 A;  4QAB A;  5AFH A;  2BJ0 A;  5AIN A;  4HFE A;  4X5T A;  4D01 A;  3WTJ A;  3WTM A;  4NZB A;  3WIP A;  4HQP A;  2XQ3 A;  1UX2 A;  4B5D A;  2XQ7 A;  4WV9 A;  2Y58 A;  3ZDH A;  4A97 A;  2PGZ A;  4ZZB A;  4F8H A;  2XZ6 A;  4XK9 A;  3SQ6 A;  3WTH A;  4AFH A;  5AFK A;  4ZR6 A;  3TLW A;  4EZ1 A;  1I9B A;  2PH9 A;  4LML A;  3WTL A;  2BG9 E;  2BG9 A;  4BFQ A;  3ZDG A;  4BQT A;  5HEG A;  5IUX A;  5AFL A;  5HEH A;  2Y54 A;  3WTO A;  2BG9 B;  2YME A;  4TWF A;  2XNU A;  3RHW A;  2X00 A;  4AFT A;  2WN9 A;  2Y56 A;  4ILC A;  2X00 D;  4TWH A;  4UM3 A;  3SIO A;  3UU5 A;  4DBM A;  2YOE A;  3JAF A;  4AFG A;  4FRR A;  5HEU A;  2UZ6 A;  2YN6 A;  2BYN A;  2WNL A;  4ZJT A;  5L47 A;  4ILA A;  2YKS A;  3PEO A;  2QC1 B;  5HCM A;  5CFB A;  4PIR A;  2XYS A;  4HFC A;  3EHZ A;  3C79 A;  5TVC A;  5L4E A;  5CO5 A;  5J5G A;  4NPP A;  4A98 A;  3WTI A;  3U8L A;  2WNC A;  3U8K A;  5KZU A;  5AFJ A;  5HEO A;  2XNT A;  3GUA A;  3SH1 A;  2BYQ A;  3C84 A;  4IRE A;  5J0Z A;  4LMK A;  5J5H A;  2XQ8 A;  2ZJU A;  3IGQ A;  3P50 A;  2XQ4 A;  3JAD A;  1UV6 A;  4IL4 A;  4TNW A;  2Y7Y A;  4UM3 S;  2C9T A;  5SYO A;  4QH4 A;  4ZK4 A;  3P4W A;  3WTK A;  3U8M A;  5HEJ A;  5L4H A;  3RI5 A;  2W8F A;  4HFH A;  2XYT A;  5HCJ A;  3T4M A;  3UU8 A;  4HFI A;  2XQA A;  4QH1 A;  4ILB A;  4HFB A;  4UXU A;  2BR8 A;  4COF A;  5LXB A;  2BR7 A;  4QAC A;  5J5F A;  3UU4 A;  5AFM A;  2WNJ A;  4ZK1 A;  5BW2 A;  4UY2 A;  3EAM A;  3RIF A;  5AFM B;  3UQ7 A;  2BG9 C;  3RIA A;  2XQ5 A;  4ZRU A;  3TLV A;  5AFN A;  3UU6 A;  2XZ5 A;  4XHE A;  3U8J A;  4ZJS A;  2YMD A;  2XQ6 A;  2BYR A;  4TNV A;  5LG3 A;  3RQW A;  3TLU A;  3UUB A;  3U8N A;  5BRX A;  4QAA A;  2Y57 A;  2XQ9 A;  5J5I A;  4LMJ A;  3ZKR A;  3TLT A;  4QH5 A;  3JAE A;  5KE4 A;  3SQ9 A;  3LSV A;  3RQU A;  4IL9 A;  4ALX A;  4ZZC A;  2WZY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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