2Y56A

Fragment growing induces conformational changes in acetylcholine- binding protein: a structural and thermodynamic analysis - (compound 3)
Total Genus 45
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
205
structure length
205
Chain Sequence
QANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKVDSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGVTCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Receptor
source organism Aplysia californica
publication title Fragment Growing Induces Conformational Changes in Acetylcholine-Binding Protein: A Structural and Thermodynamic Analysis.
pubmed doi rcsb
molecule keywords SOLUBLE ACETYLCHOLINE RECEPTOR
total genus 45
structure length 205
sequence length 205
chains with identical sequence B, C, D, E
ec nomenclature
pdb deposition date 2011-01-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 2y56A00
3TLSA 2UZ6A 5LG3A 4UM3A 2WNCA 5AFMB 4AFHA 2ZJVA 4QACA 2XQ7A 4XHEA 4TNVA 2XNVA 2VL0A 4FRRA 2WN9A 3UQ4A 4A98A 2XZ6A 2XQAA 4LMLA 4COFA 3SQ9A 3C84A 1UW6A 3RQWA 4IL4A 2X00A 1I9BA 2WNJA 5JMEA 3WTOA 3RIAA 3IGQA 3RQUA 2BYSA 2YMEA 4TWDA 5AFJA 3UU8A 2QC1B 5CFBA 2WZYA 4ZZCA 4BQTA 3P50A 2BYPA 2BYQA 2Y58A 3UU3A 3WTLA 2ZJUA 5L47A 3TLTA 3GUAA 3EHZA 4HFHA 3SH1A 3U8JA 3PMZA 5LXBA 3UU4A 3PEOA 2XQ3A 4ALXA 4HFBA 4ZR6A 4ZZBA 4QAAA 3T4MA 4EZ1A 4UXUA 4ZJSA 4UM3P 4UY2A 5J5IA 3JADA 4UM3S 3LSVA 5AFLA 3U8KA 4QH1A 5HEHA 5FJVA 3UQ7A 3RHWA 5AFMA 3U8NA 4HFCA 2Y56A 5J5HA 4Z90A 4LMJA 3U8LA 4UM1A 2XYSA 3JAEA 2XQ8A 4A97A 4ILCA 3EAMA 5BRXA 2XZ5A 4ZJTA 2XQ4A 2XQ9A 2XNTA 5IUXA 5BW2A 3U8MA 3JAFA 3TLVA 3SQ6A 2XQ6A 4ILBA 4D01A 5J5GA 2BG9E 5CO5A 5L4EA 5HEOA 3TLWA 2BYRA 3C79A 2XNUA 4F8HA 3EI0A 5AFHA 3ZDHA 2XYTA 4ILAA 4PIRA 4HFDA 3WTJA 2PGZA 4QH4A 3WIPA 4NPPA 5HEJA 2YOEA 4ZK1A 2Y54A 5J5FA 2BG9C 5HCJA 5KZUA 5L4HA 1UV6A 4ZRUA 3WTKA 4AFGA 4HQPA 5HCMA 2C9TA 3UU6A 3P4WA 4LMKA 4DBMA 4HFEA 3RI5A 2BG9B 4TWFA 4QABA 5AINA 3UUBA 2X00D 3WTIA 5TVCA 4TWHA 4WV9A 4AFTA 5KE4A 3WTHA 2Y57A 2YN6A 2W8FA 1UX2A 2BG9A 4HFIA 3RIFA 2BJ0A 4NZBA 3TLUA 2BYNA 2BR7A 4IREA 2BR8A 4Z91A 2XQ5A 5AFNA 2WNLA 4BFQA 3SIOA 5HEGA 4IL9A 3UU5A 2W8GA 3WTNA 5SYOA 3ZDGA 5BP0A 3WTMA 5J0ZA 4QH5A 3ZKRA 4X5TA 2Y7YA 5AFKA 4ZK4A 4XK9A 2YKSA 4B5DA 2PH9A 4TNWA 2YMDA 5HEUA
chains in the Genus database with same CATH superfamily
3TLSA 2UZ6A 5LG3A 4UM3A 2WNCA 5AFMB 4AFHA 2ZJVA 4QACA 2XQ7A 4XHEA 4TNVA 2XNVA 2VL0A 4FRRA 2WN9A 3UQ4A 4A98A 2XZ6A 2XQAA 4LMLA 4COFA 3SQ9A 3C84A 1UW6A 3RQWA 4IL4A 2X00A 1I9BA 2WNJA 5JMEA 3WTOA 3RIAA 3IGQA 3RQUA 2BYSA 2YMEA 4TWDA 5AFJA 3UU8A 2QC1B 5CFBA 2WZYA 4ZZCA 4BQTA 3P50A 2BYPA 2BYQA 2Y58A 3UU3A 3WTLA 2ZJUA 5L47A 3TLTA 3GUAA 3EHZA 4HFHA 3SH1A 3U8JA 3PMZA 5LXBA 3UU4A 3PEOA 2XQ3A 4ALXA 4HFBA 4ZR6A 4ZZBA 4QAAA 3T4MA 4EZ1A 4UXUA 4ZJSA 4UM3P 4UY2A 5J5IA 3JADA 4UM3S 3LSVA 5AFLA 3U8KA 4QH1A 5HEHA 5FJVA 3UQ7A 3RHWA 5AFMA 3U8NA 4HFCA 2Y56A 5J5HA 4Z90A 4LMJA 3U8LA 4UM1A 2XYSA 3JAEA 2XQ8A 4A97A 4ILCA 3EAMA 5BRXA 2XZ5A 4ZJTA 2XQ4A 2XQ9A 2XNTA 5IUXA 5BW2A 3U8MA 3JAFA 3TLVA 3SQ6A 2XQ6A 4ILBA 4D01A 5J5GA 2BG9E 5CO5A 5L4EA 5HEOA 3TLWA 2BYRA 3C79A 2XNUA 4F8HA 3EI0A 5AFHA 3ZDHA 2XYTA 4ILAA 4PIRA 4HFDA 3WTJA 2PGZA 4QH4A 3WIPA 4NPPA 5HEJA 2YOEA 4ZK1A 2Y54A 5J5FA 2BG9C 5HCJA 5KZUA 5L4HA 1UV6A 4ZRUA 3WTKA 4AFGA 4HQPA 5HCMA 2C9TA 3UU6A 3P4WA 4LMKA 4DBMA 4HFEA 3RI5A 2BG9B 4TWFA 4QABA 5AINA 3UUBA 2X00D 3WTIA 5TVCA 4TWHA 4WV9A 4AFTA 5KE4A 3WTHA 2Y57A 2YN6A 2W8FA 1UX2A 2BG9A 4HFIA 3RIFA 2BJ0A 4NZBA 3TLUA 2BYNA 2BR7A 4IREA 2BR8A 4Z91A 2XQ5A 5AFNA 2WNLA 4BFQA 3SIOA 5HEGA 4IL9A 3UU5A 2W8GA 3WTNA 5SYOA 3ZDGA 5BP0A 3WTMA 5J0ZA 4QH5A 3ZKRA 4X5TA 2Y7YA 5AFKA 4ZK4A 4XK9A 2YKSA 4B5DA 2PH9A 4TNWA 2YMDA 5HEUA
chains in the Genus database with same CATH topology
3TLSA 2UZ6A 5LG3A 4UM3A 2WNCA 5AFMB 4AFHA 2ZJVA 4QACA 2XQ7A 4XHEA 4TNVA 2XNVA 2VL0A 4FRRA 2WN9A 3UQ4A 4A98A 2XZ6A 2XQAA 4LMLA 4COFA 3SQ9A 3C84A 1UW6A 3RQWA 4IL4A 2X00A 1I9BA 2WNJA 5JMEA 3WTOA 3RIAA 3IGQA 3RQUA 2BYSA 2YMEA 4TWDA 5AFJA 3UU8A 2QC1B 5CFBA 2WZYA 4ZZCA 4BQTA 3P50A 2BYPA 2BYQA 2Y58A 3UU3A 3WTLA 2ZJUA 5L47A 3TLTA 3GUAA 3EHZA 4HFHA 3SH1A 3U8JA 3PMZA 5LXBA 3UU4A 3PEOA 2XQ3A 4ALXA 4HFBA 4ZR6A 4ZZBA 4QAAA 3T4MA 4EZ1A 4UXUA 4ZJSA 4UM3P 4UY2A 5J5IA 3JADA 4UM3S 3LSVA 5AFLA 3U8KA 4QH1A 5HEHA 5FJVA 3UQ7A 3RHWA 5AFMA 3U8NA 4HFCA 2Y56A 5J5HA 4Z90A 4LMJA 3U8LA 4UM1A 2XYSA 3JAEA 2XQ8A 4A97A 4ILCA 3EAMA 5BRXA 2XZ5A 4ZJTA 2XQ4A 2XQ9A 2XNTA 5IUXA 5BW2A 3U8MA 3JAFA 3TLVA 3SQ6A 2XQ6A 4ILBA 4D01A 5J5GA 2BG9E 5CO5A 5L4EA 5HEOA 3TLWA 2BYRA 3C79A 2XNUA 4F8HA 3EI0A 5AFHA 3ZDHA 2XYTA 4ILAA 4PIRA 4HFDA 3WTJA 2PGZA 4QH4A 3WIPA 4NPPA 5HEJA 2YOEA 4ZK1A 2Y54A 5J5FA 2BG9C 5HCJA 5KZUA 5L4HA 1UV6A 4ZRUA 3WTKA 4AFGA 4HQPA 5HCMA 2C9TA 3UU6A 3P4WA 4LMKA 4DBMA 4HFEA 3RI5A 2BG9B 4TWFA 4QABA 5AINA 3UUBA 2X00D 3WTIA 5TVCA 4TWHA 4WV9A 4AFTA 5KE4A 3WTHA 2Y57A 2YN6A 2W8FA 1UX2A 2BG9A 4HFIA 3RIFA 2BJ0A 4NZBA 3TLUA 2BYNA 2BR7A 4IREA 2BR8A 4Z91A 2XQ5A 5AFNA 2WNLA 4BFQA 3SIOA 5HEGA 4IL9A 3UU5A 2W8GA 3WTNA 5SYOA 3ZDGA 5BP0A 3WTMA 5J0ZA 4QH5A 3ZKRA 4X5TA 2Y7YA 5AFKA 4ZK4A 4XK9A 2YKSA 4B5DA 2PH9A 4TNWA 2YMDA 5HEUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TLS A;  2UZ6 A;  5LG3 A;  4UM3 A;  2WNC A;  5AFM B;  4AFH A;  2ZJV A;  4QAC A;  2XQ7 A;  4XHE A;  4TNV A;  2XNV A;  2VL0 A;  4FRR A;  2WN9 A;  3UQ4 A;  4A98 A;  2XZ6 A;  2XQA A;  4LML A;  4COF A;  3SQ9 A;  3C84 A;  1UW6 A;  3RQW A;  4IL4 A;  2X00 A;  1I9B A;  2WNJ A;  5JME A;  3WTO A;  3RIA A;  3IGQ A;  3RQU A;  2BYS A;  2YME A;  4TWD A;  5AFJ A;  3UU8 A;  2QC1 B;  5CFB A;  2WZY A;  4ZZC A;  4BQT A;  3P50 A;  2BYP A;  2BYQ A;  2Y58 A;  3UU3 A;  3WTL A;  2ZJU A;  5L47 A;  3TLT A;  3GUA A;  3EHZ A;  4HFH A;  3SH1 A;  3U8J A;  3PMZ A;  5LXB A;  3UU4 A;  3PEO A;  2XQ3 A;  4ALX A;  4HFB A;  4ZR6 A;  4ZZB A;  4QAA A;  3T4M A;  4EZ1 A;  4UXU A;  4ZJS A;  4UM3 P;  4UY2 A;  5J5I A;  3JAD A;  4UM3 S;  3LSV A;  5AFL A;  3U8K A;  4QH1 A;  5HEH A;  5FJV A;  3UQ7 A;  3RHW A;  5AFM A;  3U8N A;  4HFC A;  2Y56 A;  5J5H A;  4Z90 A;  4LMJ A;  3U8L A;  4UM1 A;  2XYS A;  3JAE A;  2XQ8 A;  4A97 A;  4ILC A;  3EAM A;  5BRX A;  2XZ5 A;  4ZJT A;  2XQ4 A;  2XQ9 A;  2XNT A;  5IUX A;  5BW2 A;  3U8M A;  3JAF A;  3TLV A;  3SQ6 A;  2XQ6 A;  4ILB A;  4D01 A;  5J5G A;  2BG9 E;  5CO5 A;  5L4E A;  5HEO A;  3TLW A;  2BYR A;  3C79 A;  2XNU A;  4F8H A;  3EI0 A;  5AFH A;  3ZDH A;  2XYT A;  4ILA A;  4PIR A;  4HFD A;  3WTJ A;  2PGZ A;  4QH4 A;  3WIP A;  4NPP A;  5HEJ A;  2YOE A;  4ZK1 A;  2Y54 A;  5J5F A;  2BG9 C;  5HCJ A;  5KZU A;  5L4H A;  1UV6 A;  4ZRU A;  3WTK A;  4AFG A;  4HQP A;  5HCM A;  2C9T A;  3UU6 A;  3P4W A;  4LMK A;  4DBM A;  4HFE A;  3RI5 A;  2BG9 B;  4TWF A;  4QAB A;  5AIN A;  3UUB A;  2X00 D;  3WTI A;  5TVC A;  4TWH A;  4WV9 A;  4AFT A;  5KE4 A;  3WTH A;  2Y57 A;  2YN6 A;  2W8F A;  1UX2 A;  2BG9 A;  4HFI A;  3RIF A;  2BJ0 A;  4NZB A;  3TLU A;  2BYN A;  2BR7 A;  4IRE A;  2BR8 A;  4Z91 A;  2XQ5 A;  5AFN A;  2WNL A;  4BFQ A;  3SIO A;  5HEG A;  4IL9 A;  3UU5 A;  2W8G A;  3WTN A;  5SYO A;  3ZDG A;  5BP0 A;  3WTM A;  5J0Z A;  4QH5 A;  3ZKR A;  4X5T A;  2Y7Y A;  5AFK A;  4ZK4 A;  4XK9 A;  2YKS A;  4B5D A;  2PH9 A;  4TNW A;  2YMD A;  5HEU A; 
#chains in the Genus database with same CATH topology
 3TLS A;  2UZ6 A;  5LG3 A;  4UM3 A;  2WNC A;  5AFM B;  4AFH A;  2ZJV A;  4QAC A;  2XQ7 A;  4XHE A;  4TNV A;  2XNV A;  2VL0 A;  4FRR A;  2WN9 A;  3UQ4 A;  4A98 A;  2XZ6 A;  2XQA A;  4LML A;  4COF A;  3SQ9 A;  3C84 A;  1UW6 A;  3RQW A;  4IL4 A;  2X00 A;  1I9B A;  2WNJ A;  5JME A;  3WTO A;  3RIA A;  3IGQ A;  3RQU A;  2BYS A;  2YME A;  4TWD A;  5AFJ A;  3UU8 A;  2QC1 B;  5CFB A;  2WZY A;  4ZZC A;  4BQT A;  3P50 A;  2BYP A;  2BYQ A;  2Y58 A;  3UU3 A;  3WTL A;  2ZJU A;  5L47 A;  3TLT A;  3GUA A;  3EHZ A;  4HFH A;  3SH1 A;  3U8J A;  3PMZ A;  5LXB A;  3UU4 A;  3PEO A;  2XQ3 A;  4ALX A;  4HFB A;  4ZR6 A;  4ZZB A;  4QAA A;  3T4M A;  4EZ1 A;  4UXU A;  4ZJS A;  4UM3 P;  4UY2 A;  5J5I A;  3JAD A;  4UM3 S;  3LSV A;  5AFL A;  3U8K A;  4QH1 A;  5HEH A;  5FJV A;  3UQ7 A;  3RHW A;  5AFM A;  3U8N A;  4HFC A;  2Y56 A;  5J5H A;  4Z90 A;  4LMJ A;  3U8L A;  4UM1 A;  2XYS A;  3JAE A;  2XQ8 A;  4A97 A;  4ILC A;  3EAM A;  5BRX A;  2XZ5 A;  4ZJT A;  2XQ4 A;  2XQ9 A;  2XNT A;  5IUX A;  5BW2 A;  3U8M A;  3JAF A;  3TLV A;  3SQ6 A;  2XQ6 A;  4ILB A;  4D01 A;  5J5G A;  2BG9 E;  5CO5 A;  5L4E A;  5HEO A;  3TLW A;  2BYR A;  3C79 A;  2XNU A;  4F8H A;  3EI0 A;  5AFH A;  3ZDH A;  2XYT A;  4ILA A;  4PIR A;  4HFD A;  3WTJ A;  2PGZ A;  4QH4 A;  3WIP A;  4NPP A;  5HEJ A;  2YOE A;  4ZK1 A;  2Y54 A;  5J5F A;  2BG9 C;  5HCJ A;  5KZU A;  5L4H A;  1UV6 A;  4ZRU A;  3WTK A;  4AFG A;  4HQP A;  5HCM A;  2C9T A;  3UU6 A;  3P4W A;  4LMK A;  4DBM A;  4HFE A;  3RI5 A;  2BG9 B;  4TWF A;  4QAB A;  5AIN A;  3UUB A;  2X00 D;  3WTI A;  5TVC A;  4TWH A;  4WV9 A;  4AFT A;  5KE4 A;  3WTH A;  2Y57 A;  2YN6 A;  2W8F A;  1UX2 A;  2BG9 A;  4HFI A;  3RIF A;  2BJ0 A;  4NZB A;  3TLU A;  2BYN A;  2BR7 A;  4IRE A;  2BR8 A;  4Z91 A;  2XQ5 A;  5AFN A;  2WNL A;  4BFQ A;  3SIO A;  5HEG A;  4IL9 A;  3UU5 A;  2W8G A;  3WTN A;  5SYO A;  3ZDG A;  5BP0 A;  3WTM A;  5J0Z A;  4QH5 A;  3ZKR A;  4X5T A;  2Y7Y A;  5AFK A;  4ZK4 A;  4XK9 A;  2YKS A;  4B5D A;  2PH9 A;  4TNW A;  2YMD A;  5HEU A; 
#chains in the Genus database with same CATH homology
 3TLS A;  2UZ6 A;  5LG3 A;  4UM3 A;  2WNC A;  5AFM B;  4AFH A;  2ZJV A;  4QAC A;  2XQ7 A;  4XHE A;  4TNV A;  2XNV A;  2VL0 A;  4FRR A;  2WN9 A;  3UQ4 A;  4A98 A;  2XZ6 A;  2XQA A;  4LML A;  4COF A;  3SQ9 A;  3C84 A;  1UW6 A;  3RQW A;  4IL4 A;  2X00 A;  1I9B A;  2WNJ A;  5JME A;  3WTO A;  3RIA A;  3IGQ A;  3RQU A;  2BYS A;  2YME A;  4TWD A;  5AFJ A;  3UU8 A;  2QC1 B;  5CFB A;  2WZY A;  4ZZC A;  4BQT A;  3P50 A;  2BYP A;  2BYQ A;  2Y58 A;  3UU3 A;  3WTL A;  2ZJU A;  5L47 A;  3TLT A;  3GUA A;  3EHZ A;  4HFH A;  3SH1 A;  3U8J A;  3PMZ A;  5LXB A;  3UU4 A;  3PEO A;  2XQ3 A;  4ALX A;  4HFB A;  4ZR6 A;  4ZZB A;  4QAA A;  3T4M A;  4EZ1 A;  4UXU A;  4ZJS A;  4UM3 P;  4UY2 A;  5J5I A;  3JAD A;  4UM3 S;  3LSV A;  5AFL A;  3U8K A;  4QH1 A;  5HEH A;  5FJV A;  3UQ7 A;  3RHW A;  5AFM A;  3U8N A;  4HFC A;  2Y56 A;  5J5H A;  4Z90 A;  4LMJ A;  3U8L A;  4UM1 A;  2XYS A;  3JAE A;  2XQ8 A;  4A97 A;  4ILC A;  3EAM A;  5BRX A;  2XZ5 A;  4ZJT A;  2XQ4 A;  2XQ9 A;  2XNT A;  5IUX A;  5BW2 A;  3U8M A;  3JAF A;  3TLV A;  3SQ6 A;  2XQ6 A;  4ILB A;  4D01 A;  5J5G A;  2BG9 E;  5CO5 A;  5L4E A;  5HEO A;  3TLW A;  2BYR A;  3C79 A;  2XNU A;  4F8H A;  3EI0 A;  5AFH A;  3ZDH A;  2XYT A;  4ILA A;  4PIR A;  4HFD A;  3WTJ A;  2PGZ A;  4QH4 A;  3WIP A;  4NPP A;  5HEJ A;  2YOE A;  4ZK1 A;  2Y54 A;  5J5F A;  2BG9 C;  5HCJ A;  5KZU A;  5L4H A;  1UV6 A;  4ZRU A;  3WTK A;  4AFG A;  4HQP A;  5HCM A;  2C9T A;  3UU6 A;  3P4W A;  4LMK A;  4DBM A;  4HFE A;  3RI5 A;  2BG9 B;  4TWF A;  4QAB A;  5AIN A;  3UUB A;  2X00 D;  3WTI A;  5TVC A;  4TWH A;  4WV9 A;  4AFT A;  5KE4 A;  3WTH A;  2Y57 A;  2YN6 A;  2W8F A;  1UX2 A;  2BG9 A;  4HFI A;  3RIF A;  2BJ0 A;  4NZB A;  3TLU A;  2BYN A;  2BR7 A;  4IRE A;  2BR8 A;  4Z91 A;  2XQ5 A;  5AFN A;  2WNL A;  4BFQ A;  3SIO A;  5HEG A;  4IL9 A;  3UU5 A;  2W8G A;  3WTN A;  5SYO A;  3ZDG A;  5BP0 A;  3WTM A;  5J0Z A;  4QH5 A;  3ZKR A;  4X5T A;  2Y7Y A;  5AFK A;  4ZK4 A;  4XK9 A;  2YKS A;  4B5D A;  2PH9 A;  4TNW A;  2YMD A;  5HEU A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...