2Y57A

Fragment growing induces conformational changes in acetylcholine- binding protein: a structural and thermodynamic analysis - (compound 4)
Total Genus 44
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
205
structure length
205
Chain Sequence
QANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKVDSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGVTCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Receptor
source organism Aplysia californica
publication title Fragment Growing Induces Conformational Changes in Acetylcholine-Binding Protein: A Structural and Thermodynamic Analysis.
pubmed doi rcsb
molecule keywords SOLUBLE ACETYLCHOLINE RECEPTOR
total genus 44
structure length 205
sequence length 205
chains with identical sequence B, C, D, E
ec nomenclature
pdb deposition date 2011-01-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 2y57A00
4HFBA 3SQ9A 3RIFA 4TNWA 2XQ3A 4PIRA 4QACA 4LMKA 5BP0A 2BG9C 2Y57A 4ILBA 5HCMA 4HQPA 5JMEA 2BG9A 4ZZCA 4IREA 3TLSA 4HFHA 1UV6A 3U8LA 3JADA 4A98A 4QH5A 3SIOA 3U8NA 3IGQA 2BYPA 2BJ0A 3RHWA 2PH9A 2BR7A 3UUBA 2BYQA 4FRRA 3T4MA 2BG9B 2XNUA 4IL9A 4BFQA 1UW6A 4AFTA 4ZJTA 3P50A 3PEOA 4ILAA 5J5HA 2C9TA 4ALXA 4QAAA 1UX2A 3RIAA 2YKSA 4TWHA 4ZK4A 4AFHA 5J0ZA 2XQ4A 3UU5A 5BW2A 4HFCA 3UQ4A 4BQTA 3UU3A 2XYSA 2YOEA 4UXUA 3UU4A 2XZ6A 3RQUA 3JAEA 3JAFA 2XQ6A 2WNJA 5AFLA 2WZYA 4IL4A 4F8HA 3WTJA 5J5IA 4Z91A 2XNVA 5KE4A 3WTHA 5AFJA 3WTLA 5AFHA 2XQ9A 2BYNA 2XQ7A 2Y7YA 4UM3S 4LMLA 3PMZA 4A97A 3P4WA 3ZDHA 4DBMA 4NPPA 4TNVA 2UZ6A 3TLTA 5HEHA 2WNLA 5KZUA 5LG3A 5CFBA 4XHEA 3EAMA 4D01A 3UQ7A 2ZJUA 4NZBA 3LSVA 4COFA 2BYRA 4AFGA 3U8KA 2WN9A 4QABA 2W8GA 5L4HA 5L47A 5J5GA 4ZZBA 4WV9A 3SH1A 4ILCA 2YN6A 5LXBA 5HEJA 3WTKA 4X5TA 4ZJSA 3C84A 4UM3A 2BR8A 5J5FA 5HEOA 3EI0A 5HEUA 4HFIA 3ZKRA 2Y54A 2XQAA 4UM3P 4HFDA 2YMDA 3WIPA 2XYTA 4TWDA 3GUAA 4B5DA 3WTIA 3UU8A 5AFMA 2YMEA 3RQWA 3WTNA 3ZDGA 5TVCA 2XNTA 2XZ5A 2Y56A 2Y58A 2W8FA 2VL0A 4UY2A 3SQ6A 5AINA 4QH4A 3RI5A 2BYSA 2X00A 5FJVA 5BRXA 4HFEA 3TLUA 4XK9A 2QC1B 4ZR6A 5HCJA 3TLWA 3WTOA 5AFMB 4LMJA 2XQ5A 3TLVA 2WNCA 3UU6A 5IUXA 4EZ1A 4TWFA 4ZK1A 5HEGA 3C79A 4UM1A 2PGZA 4QH1A 3U8JA 5SYOA 5AFNA 2XQ8A 3EHZA 5CO5A 3U8MA 2BG9E 2ZJVA 5L4EA 3WTMA 5AFKA 1I9BA 4ZRUA 2X00D 4Z90A
chains in the Genus database with same CATH superfamily
4HFBA 3SQ9A 3RIFA 4TNWA 2XQ3A 4PIRA 4QACA 4LMKA 5BP0A 2BG9C 2Y57A 4ILBA 5HCMA 4HQPA 5JMEA 2BG9A 4ZZCA 4IREA 3TLSA 4HFHA 1UV6A 3U8LA 3JADA 4A98A 4QH5A 3SIOA 3U8NA 3IGQA 2BYPA 2BJ0A 3RHWA 2PH9A 2BR7A 3UUBA 2BYQA 4FRRA 3T4MA 2BG9B 2XNUA 4IL9A 4BFQA 1UW6A 4AFTA 4ZJTA 3P50A 3PEOA 4ILAA 5J5HA 2C9TA 4ALXA 4QAAA 1UX2A 3RIAA 2YKSA 4TWHA 4ZK4A 4AFHA 5J0ZA 2XQ4A 3UU5A 5BW2A 4HFCA 3UQ4A 4BQTA 3UU3A 2XYSA 2YOEA 4UXUA 3UU4A 2XZ6A 3RQUA 3JAEA 3JAFA 2XQ6A 2WNJA 5AFLA 2WZYA 4IL4A 4F8HA 3WTJA 5J5IA 4Z91A 2XNVA 5KE4A 3WTHA 5AFJA 3WTLA 5AFHA 2XQ9A 2BYNA 2XQ7A 2Y7YA 4UM3S 4LMLA 3PMZA 4A97A 3P4WA 3ZDHA 4DBMA 4NPPA 4TNVA 2UZ6A 3TLTA 5HEHA 2WNLA 5KZUA 5LG3A 5CFBA 4XHEA 3EAMA 4D01A 3UQ7A 2ZJUA 4NZBA 3LSVA 4COFA 2BYRA 4AFGA 3U8KA 2WN9A 4QABA 2W8GA 5L4HA 5L47A 5J5GA 4ZZBA 4WV9A 3SH1A 4ILCA 2YN6A 5LXBA 5HEJA 3WTKA 4X5TA 4ZJSA 3C84A 4UM3A 2BR8A 5J5FA 5HEOA 3EI0A 5HEUA 4HFIA 3ZKRA 2Y54A 2XQAA 4UM3P 4HFDA 2YMDA 3WIPA 2XYTA 4TWDA 3GUAA 4B5DA 3WTIA 3UU8A 5AFMA 2YMEA 3RQWA 3WTNA 3ZDGA 5TVCA 2XNTA 2XZ5A 2Y56A 2Y58A 2W8FA 2VL0A 4UY2A 3SQ6A 5AINA 4QH4A 3RI5A 2BYSA 2X00A 5FJVA 5BRXA 4HFEA 3TLUA 4XK9A 2QC1B 4ZR6A 5HCJA 3TLWA 3WTOA 5AFMB 4LMJA 2XQ5A 3TLVA 2WNCA 3UU6A 5IUXA 4EZ1A 4TWFA 4ZK1A 5HEGA 3C79A 4UM1A 2PGZA 4QH1A 3U8JA 5SYOA 5AFNA 2XQ8A 3EHZA 5CO5A 3U8MA 2BG9E 2ZJVA 5L4EA 3WTMA 5AFKA 1I9BA 4ZRUA 2X00D 4Z90A
chains in the Genus database with same CATH topology
4HFBA 3SQ9A 3RIFA 4TNWA 2XQ3A 4PIRA 4QACA 4LMKA 5BP0A 2BG9C 2Y57A 4ILBA 5HCMA 4HQPA 5JMEA 2BG9A 4ZZCA 4IREA 3TLSA 4HFHA 1UV6A 3U8LA 3JADA 4A98A 4QH5A 3SIOA 3U8NA 3IGQA 2BYPA 2BJ0A 3RHWA 2PH9A 2BR7A 3UUBA 2BYQA 4FRRA 3T4MA 2BG9B 2XNUA 4IL9A 4BFQA 1UW6A 4AFTA 4ZJTA 3P50A 3PEOA 4ILAA 5J5HA 2C9TA 4ALXA 4QAAA 1UX2A 3RIAA 2YKSA 4TWHA 4ZK4A 4AFHA 5J0ZA 2XQ4A 3UU5A 5BW2A 4HFCA 3UQ4A 4BQTA 3UU3A 2XYSA 2YOEA 4UXUA 3UU4A 2XZ6A 3RQUA 3JAEA 3JAFA 2XQ6A 2WNJA 5AFLA 2WZYA 4IL4A 4F8HA 3WTJA 5J5IA 4Z91A 2XNVA 5KE4A 3WTHA 5AFJA 3WTLA 5AFHA 2XQ9A 2BYNA 2XQ7A 2Y7YA 4UM3S 4LMLA 3PMZA 4A97A 3P4WA 3ZDHA 4DBMA 4NPPA 4TNVA 2UZ6A 3TLTA 5HEHA 2WNLA 5KZUA 5LG3A 5CFBA 4XHEA 3EAMA 4D01A 3UQ7A 2ZJUA 4NZBA 3LSVA 4COFA 2BYRA 4AFGA 3U8KA 2WN9A 4QABA 2W8GA 5L4HA 5L47A 5J5GA 4ZZBA 4WV9A 3SH1A 4ILCA 2YN6A 5LXBA 5HEJA 3WTKA 4X5TA 4ZJSA 3C84A 4UM3A 2BR8A 5J5FA 5HEOA 3EI0A 5HEUA 4HFIA 3ZKRA 2Y54A 2XQAA 4UM3P 4HFDA 2YMDA 3WIPA 2XYTA 4TWDA 3GUAA 4B5DA 3WTIA 3UU8A 5AFMA 2YMEA 3RQWA 3WTNA 3ZDGA 5TVCA 2XNTA 2XZ5A 2Y56A 2Y58A 2W8FA 2VL0A 4UY2A 3SQ6A 5AINA 4QH4A 3RI5A 2BYSA 2X00A 5FJVA 5BRXA 4HFEA 3TLUA 4XK9A 2QC1B 4ZR6A 5HCJA 3TLWA 3WTOA 5AFMB 4LMJA 2XQ5A 3TLVA 2WNCA 3UU6A 5IUXA 4EZ1A 4TWFA 4ZK1A 5HEGA 3C79A 4UM1A 2PGZA 4QH1A 3U8JA 5SYOA 5AFNA 2XQ8A 3EHZA 5CO5A 3U8MA 2BG9E 2ZJVA 5L4EA 3WTMA 5AFKA 1I9BA 4ZRUA 2X00D 4Z90A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HFB A;  3SQ9 A;  3RIF A;  4TNW A;  2XQ3 A;  4PIR A;  4QAC A;  4LMK A;  5BP0 A;  2BG9 C;  2Y57 A;  4ILB A;  5HCM A;  4HQP A;  5JME A;  2BG9 A;  4ZZC A;  4IRE A;  3TLS A;  4HFH A;  1UV6 A;  3U8L A;  3JAD A;  4A98 A;  4QH5 A;  3SIO A;  3U8N A;  3IGQ A;  2BYP A;  2BJ0 A;  3RHW A;  2PH9 A;  2BR7 A;  3UUB A;  2BYQ A;  4FRR A;  3T4M A;  2BG9 B;  2XNU A;  4IL9 A;  4BFQ A;  1UW6 A;  4AFT A;  4ZJT A;  3P50 A;  3PEO A;  4ILA A;  5J5H A;  2C9T A;  4ALX A;  4QAA A;  1UX2 A;  3RIA A;  2YKS A;  4TWH A;  4ZK4 A;  4AFH A;  5J0Z A;  2XQ4 A;  3UU5 A;  5BW2 A;  4HFC A;  3UQ4 A;  4BQT A;  3UU3 A;  2XYS A;  2YOE A;  4UXU A;  3UU4 A;  2XZ6 A;  3RQU A;  3JAE A;  3JAF A;  2XQ6 A;  2WNJ A;  5AFL A;  2WZY A;  4IL4 A;  4F8H A;  3WTJ A;  5J5I A;  4Z91 A;  2XNV A;  5KE4 A;  3WTH A;  5AFJ A;  3WTL A;  5AFH A;  2XQ9 A;  2BYN A;  2XQ7 A;  2Y7Y A;  4UM3 S;  4LML A;  3PMZ A;  4A97 A;  3P4W A;  3ZDH A;  4DBM A;  4NPP A;  4TNV A;  2UZ6 A;  3TLT A;  5HEH A;  2WNL A;  5KZU A;  5LG3 A;  5CFB A;  4XHE A;  3EAM A;  4D01 A;  3UQ7 A;  2ZJU A;  4NZB A;  3LSV A;  4COF A;  2BYR A;  4AFG A;  3U8K A;  2WN9 A;  4QAB A;  2W8G A;  5L4H A;  5L47 A;  5J5G A;  4ZZB A;  4WV9 A;  3SH1 A;  4ILC A;  2YN6 A;  5LXB A;  5HEJ A;  3WTK A;  4X5T A;  4ZJS A;  3C84 A;  4UM3 A;  2BR8 A;  5J5F A;  5HEO A;  3EI0 A;  5HEU A;  4HFI A;  3ZKR A;  2Y54 A;  2XQA A;  4UM3 P;  4HFD A;  2YMD A;  3WIP A;  2XYT A;  4TWD A;  3GUA A;  4B5D A;  3WTI A;  3UU8 A;  5AFM A;  2YME A;  3RQW A;  3WTN A;  3ZDG A;  5TVC A;  2XNT A;  2XZ5 A;  2Y56 A;  2Y58 A;  2W8F A;  2VL0 A;  4UY2 A;  3SQ6 A;  5AIN A;  4QH4 A;  3RI5 A;  2BYS A;  2X00 A;  5FJV A;  5BRX A;  4HFE A;  3TLU A;  4XK9 A;  2QC1 B;  4ZR6 A;  5HCJ A;  3TLW A;  3WTO A;  5AFM B;  4LMJ A;  2XQ5 A;  3TLV A;  2WNC A;  3UU6 A;  5IUX A;  4EZ1 A;  4TWF A;  4ZK1 A;  5HEG A;  3C79 A;  4UM1 A;  2PGZ A;  4QH1 A;  3U8J A;  5SYO A;  5AFN A;  2XQ8 A;  3EHZ A;  5CO5 A;  3U8M A;  2BG9 E;  2ZJV A;  5L4E A;  3WTM A;  5AFK A;  1I9B A;  4ZRU A;  2X00 D;  4Z90 A; 
#chains in the Genus database with same CATH topology
 4HFB A;  3SQ9 A;  3RIF A;  4TNW A;  2XQ3 A;  4PIR A;  4QAC A;  4LMK A;  5BP0 A;  2BG9 C;  2Y57 A;  4ILB A;  5HCM A;  4HQP A;  5JME A;  2BG9 A;  4ZZC A;  4IRE A;  3TLS A;  4HFH A;  1UV6 A;  3U8L A;  3JAD A;  4A98 A;  4QH5 A;  3SIO A;  3U8N A;  3IGQ A;  2BYP A;  2BJ0 A;  3RHW A;  2PH9 A;  2BR7 A;  3UUB A;  2BYQ A;  4FRR A;  3T4M A;  2BG9 B;  2XNU A;  4IL9 A;  4BFQ A;  1UW6 A;  4AFT A;  4ZJT A;  3P50 A;  3PEO A;  4ILA A;  5J5H A;  2C9T A;  4ALX A;  4QAA A;  1UX2 A;  3RIA A;  2YKS A;  4TWH A;  4ZK4 A;  4AFH A;  5J0Z A;  2XQ4 A;  3UU5 A;  5BW2 A;  4HFC A;  3UQ4 A;  4BQT A;  3UU3 A;  2XYS A;  2YOE A;  4UXU A;  3UU4 A;  2XZ6 A;  3RQU A;  3JAE A;  3JAF A;  2XQ6 A;  2WNJ A;  5AFL A;  2WZY A;  4IL4 A;  4F8H A;  3WTJ A;  5J5I A;  4Z91 A;  2XNV A;  5KE4 A;  3WTH A;  5AFJ A;  3WTL A;  5AFH A;  2XQ9 A;  2BYN A;  2XQ7 A;  2Y7Y A;  4UM3 S;  4LML A;  3PMZ A;  4A97 A;  3P4W A;  3ZDH A;  4DBM A;  4NPP A;  4TNV A;  2UZ6 A;  3TLT A;  5HEH A;  2WNL A;  5KZU A;  5LG3 A;  5CFB A;  4XHE A;  3EAM A;  4D01 A;  3UQ7 A;  2ZJU A;  4NZB A;  3LSV A;  4COF A;  2BYR A;  4AFG A;  3U8K A;  2WN9 A;  4QAB A;  2W8G A;  5L4H A;  5L47 A;  5J5G A;  4ZZB A;  4WV9 A;  3SH1 A;  4ILC A;  2YN6 A;  5LXB A;  5HEJ A;  3WTK A;  4X5T A;  4ZJS A;  3C84 A;  4UM3 A;  2BR8 A;  5J5F A;  5HEO A;  3EI0 A;  5HEU A;  4HFI A;  3ZKR A;  2Y54 A;  2XQA A;  4UM3 P;  4HFD A;  2YMD A;  3WIP A;  2XYT A;  4TWD A;  3GUA A;  4B5D A;  3WTI A;  3UU8 A;  5AFM A;  2YME A;  3RQW A;  3WTN A;  3ZDG A;  5TVC A;  2XNT A;  2XZ5 A;  2Y56 A;  2Y58 A;  2W8F A;  2VL0 A;  4UY2 A;  3SQ6 A;  5AIN A;  4QH4 A;  3RI5 A;  2BYS A;  2X00 A;  5FJV A;  5BRX A;  4HFE A;  3TLU A;  4XK9 A;  2QC1 B;  4ZR6 A;  5HCJ A;  3TLW A;  3WTO A;  5AFM B;  4LMJ A;  2XQ5 A;  3TLV A;  2WNC A;  3UU6 A;  5IUX A;  4EZ1 A;  4TWF A;  4ZK1 A;  5HEG A;  3C79 A;  4UM1 A;  2PGZ A;  4QH1 A;  3U8J A;  5SYO A;  5AFN A;  2XQ8 A;  3EHZ A;  5CO5 A;  3U8M A;  2BG9 E;  2ZJV A;  5L4E A;  3WTM A;  5AFK A;  1I9B A;  4ZRU A;  2X00 D;  4Z90 A; 
#chains in the Genus database with same CATH homology
 4HFB A;  3SQ9 A;  3RIF A;  4TNW A;  2XQ3 A;  4PIR A;  4QAC A;  4LMK A;  5BP0 A;  2BG9 C;  2Y57 A;  4ILB A;  5HCM A;  4HQP A;  5JME A;  2BG9 A;  4ZZC A;  4IRE A;  3TLS A;  4HFH A;  1UV6 A;  3U8L A;  3JAD A;  4A98 A;  4QH5 A;  3SIO A;  3U8N A;  3IGQ A;  2BYP A;  2BJ0 A;  3RHW A;  2PH9 A;  2BR7 A;  3UUB A;  2BYQ A;  4FRR A;  3T4M A;  2BG9 B;  2XNU A;  4IL9 A;  4BFQ A;  1UW6 A;  4AFT A;  4ZJT A;  3P50 A;  3PEO A;  4ILA A;  5J5H A;  2C9T A;  4ALX A;  4QAA A;  1UX2 A;  3RIA A;  2YKS A;  4TWH A;  4ZK4 A;  4AFH A;  5J0Z A;  2XQ4 A;  3UU5 A;  5BW2 A;  4HFC A;  3UQ4 A;  4BQT A;  3UU3 A;  2XYS A;  2YOE A;  4UXU A;  3UU4 A;  2XZ6 A;  3RQU A;  3JAE A;  3JAF A;  2XQ6 A;  2WNJ A;  5AFL A;  2WZY A;  4IL4 A;  4F8H A;  3WTJ A;  5J5I A;  4Z91 A;  2XNV A;  5KE4 A;  3WTH A;  5AFJ A;  3WTL A;  5AFH A;  2XQ9 A;  2BYN A;  2XQ7 A;  2Y7Y A;  4UM3 S;  4LML A;  3PMZ A;  4A97 A;  3P4W A;  3ZDH A;  4DBM A;  4NPP A;  4TNV A;  2UZ6 A;  3TLT A;  5HEH A;  2WNL A;  5KZU A;  5LG3 A;  5CFB A;  4XHE A;  3EAM A;  4D01 A;  3UQ7 A;  2ZJU A;  4NZB A;  3LSV A;  4COF A;  2BYR A;  4AFG A;  3U8K A;  2WN9 A;  4QAB A;  2W8G A;  5L4H A;  5L47 A;  5J5G A;  4ZZB A;  4WV9 A;  3SH1 A;  4ILC A;  2YN6 A;  5LXB A;  5HEJ A;  3WTK A;  4X5T A;  4ZJS A;  3C84 A;  4UM3 A;  2BR8 A;  5J5F A;  5HEO A;  3EI0 A;  5HEU A;  4HFI A;  3ZKR A;  2Y54 A;  2XQA A;  4UM3 P;  4HFD A;  2YMD A;  3WIP A;  2XYT A;  4TWD A;  3GUA A;  4B5D A;  3WTI A;  3UU8 A;  5AFM A;  2YME A;  3RQW A;  3WTN A;  3ZDG A;  5TVC A;  2XNT A;  2XZ5 A;  2Y56 A;  2Y58 A;  2W8F A;  2VL0 A;  4UY2 A;  3SQ6 A;  5AIN A;  4QH4 A;  3RI5 A;  2BYS A;  2X00 A;  5FJV A;  5BRX A;  4HFE A;  3TLU A;  4XK9 A;  2QC1 B;  4ZR6 A;  5HCJ A;  3TLW A;  3WTO A;  5AFM B;  4LMJ A;  2XQ5 A;  3TLV A;  2WNC A;  3UU6 A;  5IUX A;  4EZ1 A;  4TWF A;  4ZK1 A;  5HEG A;  3C79 A;  4UM1 A;  2PGZ A;  4QH1 A;  3U8J A;  5SYO A;  5AFN A;  2XQ8 A;  3EHZ A;  5CO5 A;  3U8M A;  2BG9 E;  2ZJV A;  5L4E A;  3WTM A;  5AFK A;  1I9B A;  4ZRU A;  2X00 D;  4Z90 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...