2Y7YA

Aplysia californica achbp in apo state
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
205
structure length
203
Chain Sequence
QANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKVDSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGVTCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSPEPYIDVNLVVKFRER
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Receptor
source organism Aplysia californica
publication title Use of Acetylcholine Binding Protein in the Search for Novel Alpha7 Nicotinic Receptor Ligands. In Silico Docking, Pharmacological Screening, and X-Ray Analysis.
pubmed doi rcsb
molecule keywords SOLUBLE ACETYLCHOLINE RECEPTOR
total genus 50
structure length 203
sequence length 205
chains with identical sequence B, C, D, E
ec nomenclature
pdb deposition date 2011-02-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 2y7yA00
2XZ6A 3TLWA 4PIRA 3RHWA 5J5HA 3EHZA 5IUXA 5J0ZA 3WTOA 2WNLA 2Y58A 2BJ0A 4Z90A 4ILBA 4HFBA 4IREA 2ZJVA 5CO5A 3UU8A 3UU3A 3WTLA 2BYRA 3TLTA 4EZ1A 2VL0A 4ZJTA 4UM3P 2ZJUA 4WV9A 2XQ7A 2YMEA 2BYPA 4NPPA 3U8LA 3UUBA 1UW6A 4TNWA 3WTJA 3ZKRA 5AFKA 4QAAA 3UU6A 3RIAA 5HCJA 5HEHA 4ZK1A 2BYSA 4TWDA 3IGQA 5FJVA 4LMLA 2YKSA 2XQ3A 4UM3S 2QC1B 3T4MA 3SH1A 3WTNA 3PMZA 2XNTA 4BFQA 4UXUA 5KZUA 4ZJSA 2BR7A 4ZZBA 2Y7YA 5L4EA 4A98A 2X00D 3EAMA 2WNCA 4DBMA 2BYNA 3SQ9A 3SIOA 4ILCA 4UM1A 2XNUA 4HQPA 2YN6A 5L47A 4UY2A 5LG3A 4QACA 4BQTA 3P4WA 3C84A 2BYQA 2W8FA 4HFEA 2XQ6A 2BG9E 2XYTA 3UQ4A 3WTIA 4AFTA 4QABA 2BG9C 2BG9B 4XHEA 3U8JA 2Y57A 2XYSA 4QH1A 2YMDA 5AFNA 2BG9A 4HFIA 4A97A 4D01A 3RQUA 2PGZA 2XQ4A 4FRRA 5AFHA 5HEJA 3LSVA 2UZ6A 5J5GA 5BW2A 4TWHA 5AFMB 3PEOA 1UX2A 2WN9A 1UV6A 3RIFA 3RQWA 5LXBA 4COFA 5AFLA 4HFHA 5AFMA 2YOEA 2XQ9A 4QH4A 3JAEA 3TLVA 4ALXA 5CFBA 4F8HA 3EI0A 4HFDA 2BR8A 3RI5A 3UQ7A 4HFCA 2W8GA 5HEGA 3U8NA 3JADA 5HCMA 5BRXA 3SQ6A 2X00A 4UM3A 3U8KA 4Z91A 3WTHA 4ZRUA 5KE4A 2XQ5A 2WZYA 4B5DA 2XNVA 5SYOA 3TLSA 2WNJA 2XQ8A 5L4HA 3WTKA 4ZK4A 2XZ5A 3WTMA 4TWFA 3ZDHA 5TVCA 4IL4A 5J5IA 2Y54A 5JMEA 3JAFA 4IL9A 4X5TA 3U8MA 3UU5A 3P50A 2Y56A 2XQAA 4LMJA 3WIPA 4ZR6A 3UU4A 5HEOA 4AFHA 3ZDGA 4AFGA 5J5FA 4QH5A 2PH9A 5AINA 4ILAA 4NZBA 5AFJA 4TNVA 2C9TA 4XK9A 5HEUA 4LMKA 1I9BA 3GUAA 4ZZCA 3C79A 5BP0A 3TLUA
chains in the Genus database with same CATH superfamily
2XZ6A 3TLWA 4PIRA 3RHWA 5J5HA 3EHZA 5IUXA 5J0ZA 3WTOA 2WNLA 2Y58A 2BJ0A 4Z90A 4ILBA 4HFBA 4IREA 2ZJVA 5CO5A 3UU8A 3UU3A 3WTLA 2BYRA 3TLTA 4EZ1A 2VL0A 4ZJTA 4UM3P 2ZJUA 4WV9A 2XQ7A 2YMEA 2BYPA 4NPPA 3U8LA 3UUBA 1UW6A 4TNWA 3WTJA 3ZKRA 5AFKA 4QAAA 3UU6A 3RIAA 5HCJA 5HEHA 4ZK1A 2BYSA 4TWDA 3IGQA 5FJVA 4LMLA 2YKSA 2XQ3A 4UM3S 2QC1B 3T4MA 3SH1A 3WTNA 3PMZA 2XNTA 4BFQA 4UXUA 5KZUA 4ZJSA 2BR7A 4ZZBA 2Y7YA 5L4EA 4A98A 2X00D 3EAMA 2WNCA 4DBMA 2BYNA 3SQ9A 3SIOA 4ILCA 4UM1A 2XNUA 4HQPA 2YN6A 5L47A 4UY2A 5LG3A 4QACA 4BQTA 3P4WA 3C84A 2BYQA 2W8FA 4HFEA 2XQ6A 2BG9E 2XYTA 3UQ4A 3WTIA 4AFTA 4QABA 2BG9C 2BG9B 4XHEA 3U8JA 2Y57A 2XYSA 4QH1A 2YMDA 5AFNA 2BG9A 4HFIA 4A97A 4D01A 3RQUA 2PGZA 2XQ4A 4FRRA 5AFHA 5HEJA 3LSVA 2UZ6A 5J5GA 5BW2A 4TWHA 5AFMB 3PEOA 1UX2A 2WN9A 1UV6A 3RIFA 3RQWA 5LXBA 4COFA 5AFLA 4HFHA 5AFMA 2YOEA 2XQ9A 4QH4A 3JAEA 3TLVA 4ALXA 5CFBA 4F8HA 3EI0A 4HFDA 2BR8A 3RI5A 3UQ7A 4HFCA 2W8GA 5HEGA 3U8NA 3JADA 5HCMA 5BRXA 3SQ6A 2X00A 4UM3A 3U8KA 4Z91A 3WTHA 4ZRUA 5KE4A 2XQ5A 2WZYA 4B5DA 2XNVA 5SYOA 3TLSA 2WNJA 2XQ8A 5L4HA 3WTKA 4ZK4A 2XZ5A 3WTMA 4TWFA 3ZDHA 5TVCA 4IL4A 5J5IA 2Y54A 5JMEA 3JAFA 4IL9A 4X5TA 3U8MA 3UU5A 3P50A 2Y56A 2XQAA 4LMJA 3WIPA 4ZR6A 3UU4A 5HEOA 4AFHA 3ZDGA 4AFGA 5J5FA 4QH5A 2PH9A 5AINA 4ILAA 4NZBA 5AFJA 4TNVA 2C9TA 4XK9A 5HEUA 4LMKA 1I9BA 3GUAA 4ZZCA 3C79A 5BP0A 3TLUA
chains in the Genus database with same CATH topology
2XZ6A 3TLWA 4PIRA 3RHWA 5J5HA 3EHZA 5IUXA 5J0ZA 3WTOA 2WNLA 2Y58A 2BJ0A 4Z90A 4ILBA 4HFBA 4IREA 2ZJVA 5CO5A 3UU8A 3UU3A 3WTLA 2BYRA 3TLTA 4EZ1A 2VL0A 4ZJTA 4UM3P 2ZJUA 4WV9A 2XQ7A 2YMEA 2BYPA 4NPPA 3U8LA 3UUBA 1UW6A 4TNWA 3WTJA 3ZKRA 5AFKA 4QAAA 3UU6A 3RIAA 5HCJA 5HEHA 4ZK1A 2BYSA 4TWDA 3IGQA 5FJVA 4LMLA 2YKSA 2XQ3A 4UM3S 2QC1B 3T4MA 3SH1A 3WTNA 3PMZA 2XNTA 4BFQA 4UXUA 5KZUA 4ZJSA 2BR7A 4ZZBA 2Y7YA 5L4EA 4A98A 2X00D 3EAMA 2WNCA 4DBMA 2BYNA 3SQ9A 3SIOA 4ILCA 4UM1A 2XNUA 4HQPA 2YN6A 5L47A 4UY2A 5LG3A 4QACA 4BQTA 3P4WA 3C84A 2BYQA 2W8FA 4HFEA 2XQ6A 2BG9E 2XYTA 3UQ4A 3WTIA 4AFTA 4QABA 2BG9C 2BG9B 4XHEA 3U8JA 2Y57A 2XYSA 4QH1A 2YMDA 5AFNA 2BG9A 4HFIA 4A97A 4D01A 3RQUA 2PGZA 2XQ4A 4FRRA 5AFHA 5HEJA 3LSVA 2UZ6A 5J5GA 5BW2A 4TWHA 5AFMB 3PEOA 1UX2A 2WN9A 1UV6A 3RIFA 3RQWA 5LXBA 4COFA 5AFLA 4HFHA 5AFMA 2YOEA 2XQ9A 4QH4A 3JAEA 3TLVA 4ALXA 5CFBA 4F8HA 3EI0A 4HFDA 2BR8A 3RI5A 3UQ7A 4HFCA 2W8GA 5HEGA 3U8NA 3JADA 5HCMA 5BRXA 3SQ6A 2X00A 4UM3A 3U8KA 4Z91A 3WTHA 4ZRUA 5KE4A 2XQ5A 2WZYA 4B5DA 2XNVA 5SYOA 3TLSA 2WNJA 2XQ8A 5L4HA 3WTKA 4ZK4A 2XZ5A 3WTMA 4TWFA 3ZDHA 5TVCA 4IL4A 5J5IA 2Y54A 5JMEA 3JAFA 4IL9A 4X5TA 3U8MA 3UU5A 3P50A 2Y56A 2XQAA 4LMJA 3WIPA 4ZR6A 3UU4A 5HEOA 4AFHA 3ZDGA 4AFGA 5J5FA 4QH5A 2PH9A 5AINA 4ILAA 4NZBA 5AFJA 4TNVA 2C9TA 4XK9A 5HEUA 4LMKA 1I9BA 3GUAA 4ZZCA 3C79A 5BP0A 3TLUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XZ6 A;  3TLW A;  4PIR A;  3RHW A;  5J5H A;  3EHZ A;  5IUX A;  5J0Z A;  3WTO A;  2WNL A;  2Y58 A;  2BJ0 A;  4Z90 A;  4ILB A;  4HFB A;  4IRE A;  2ZJV A;  5CO5 A;  3UU8 A;  3UU3 A;  3WTL A;  2BYR A;  3TLT A;  4EZ1 A;  2VL0 A;  4ZJT A;  4UM3 P;  2ZJU A;  4WV9 A;  2XQ7 A;  2YME A;  2BYP A;  4NPP A;  3U8L A;  3UUB A;  1UW6 A;  4TNW A;  3WTJ A;  3ZKR A;  5AFK A;  4QAA A;  3UU6 A;  3RIA A;  5HCJ A;  5HEH A;  4ZK1 A;  2BYS A;  4TWD A;  3IGQ A;  5FJV A;  4LML A;  2YKS A;  2XQ3 A;  4UM3 S;  2QC1 B;  3T4M A;  3SH1 A;  3WTN A;  3PMZ A;  2XNT A;  4BFQ A;  4UXU A;  5KZU A;  4ZJS A;  2BR7 A;  4ZZB A;  2Y7Y A;  5L4E A;  4A98 A;  2X00 D;  3EAM A;  2WNC A;  4DBM A;  2BYN A;  3SQ9 A;  3SIO A;  4ILC A;  4UM1 A;  2XNU A;  4HQP A;  2YN6 A;  5L47 A;  4UY2 A;  5LG3 A;  4QAC A;  4BQT A;  3P4W A;  3C84 A;  2BYQ A;  2W8F A;  4HFE A;  2XQ6 A;  2BG9 E;  2XYT A;  3UQ4 A;  3WTI A;  4AFT A;  4QAB A;  2BG9 C;  2BG9 B;  4XHE A;  3U8J A;  2Y57 A;  2XYS A;  4QH1 A;  2YMD A;  5AFN A;  2BG9 A;  4HFI A;  4A97 A;  4D01 A;  3RQU A;  2PGZ A;  2XQ4 A;  4FRR A;  5AFH A;  5HEJ A;  3LSV A;  2UZ6 A;  5J5G A;  5BW2 A;  4TWH A;  5AFM B;  3PEO A;  1UX2 A;  2WN9 A;  1UV6 A;  3RIF A;  3RQW A;  5LXB A;  4COF A;  5AFL A;  4HFH A;  5AFM A;  2YOE A;  2XQ9 A;  4QH4 A;  3JAE A;  3TLV A;  4ALX A;  5CFB A;  4F8H A;  3EI0 A;  4HFD A;  2BR8 A;  3RI5 A;  3UQ7 A;  4HFC A;  2W8G A;  5HEG A;  3U8N A;  3JAD A;  5HCM A;  5BRX A;  3SQ6 A;  2X00 A;  4UM3 A;  3U8K A;  4Z91 A;  3WTH A;  4ZRU A;  5KE4 A;  2XQ5 A;  2WZY A;  4B5D A;  2XNV A;  5SYO A;  3TLS A;  2WNJ A;  2XQ8 A;  5L4H A;  3WTK A;  4ZK4 A;  2XZ5 A;  3WTM A;  4TWF A;  3ZDH A;  5TVC A;  4IL4 A;  5J5I A;  2Y54 A;  5JME A;  3JAF A;  4IL9 A;  4X5T A;  3U8M A;  3UU5 A;  3P50 A;  2Y56 A;  2XQA A;  4LMJ A;  3WIP A;  4ZR6 A;  3UU4 A;  5HEO A;  4AFH A;  3ZDG A;  4AFG A;  5J5F A;  4QH5 A;  2PH9 A;  5AIN A;  4ILA A;  4NZB A;  5AFJ A;  4TNV A;  2C9T A;  4XK9 A;  5HEU A;  4LMK A;  1I9B A;  3GUA A;  4ZZC A;  3C79 A;  5BP0 A;  3TLU A; 
#chains in the Genus database with same CATH topology
 2XZ6 A;  3TLW A;  4PIR A;  3RHW A;  5J5H A;  3EHZ A;  5IUX A;  5J0Z A;  3WTO A;  2WNL A;  2Y58 A;  2BJ0 A;  4Z90 A;  4ILB A;  4HFB A;  4IRE A;  2ZJV A;  5CO5 A;  3UU8 A;  3UU3 A;  3WTL A;  2BYR A;  3TLT A;  4EZ1 A;  2VL0 A;  4ZJT A;  4UM3 P;  2ZJU A;  4WV9 A;  2XQ7 A;  2YME A;  2BYP A;  4NPP A;  3U8L A;  3UUB A;  1UW6 A;  4TNW A;  3WTJ A;  3ZKR A;  5AFK A;  4QAA A;  3UU6 A;  3RIA A;  5HCJ A;  5HEH A;  4ZK1 A;  2BYS A;  4TWD A;  3IGQ A;  5FJV A;  4LML A;  2YKS A;  2XQ3 A;  4UM3 S;  2QC1 B;  3T4M A;  3SH1 A;  3WTN A;  3PMZ A;  2XNT A;  4BFQ A;  4UXU A;  5KZU A;  4ZJS A;  2BR7 A;  4ZZB A;  2Y7Y A;  5L4E A;  4A98 A;  2X00 D;  3EAM A;  2WNC A;  4DBM A;  2BYN A;  3SQ9 A;  3SIO A;  4ILC A;  4UM1 A;  2XNU A;  4HQP A;  2YN6 A;  5L47 A;  4UY2 A;  5LG3 A;  4QAC A;  4BQT A;  3P4W A;  3C84 A;  2BYQ A;  2W8F A;  4HFE A;  2XQ6 A;  2BG9 E;  2XYT A;  3UQ4 A;  3WTI A;  4AFT A;  4QAB A;  2BG9 C;  2BG9 B;  4XHE A;  3U8J A;  2Y57 A;  2XYS A;  4QH1 A;  2YMD A;  5AFN A;  2BG9 A;  4HFI A;  4A97 A;  4D01 A;  3RQU A;  2PGZ A;  2XQ4 A;  4FRR A;  5AFH A;  5HEJ A;  3LSV A;  2UZ6 A;  5J5G A;  5BW2 A;  4TWH A;  5AFM B;  3PEO A;  1UX2 A;  2WN9 A;  1UV6 A;  3RIF A;  3RQW A;  5LXB A;  4COF A;  5AFL A;  4HFH A;  5AFM A;  2YOE A;  2XQ9 A;  4QH4 A;  3JAE A;  3TLV A;  4ALX A;  5CFB A;  4F8H A;  3EI0 A;  4HFD A;  2BR8 A;  3RI5 A;  3UQ7 A;  4HFC A;  2W8G A;  5HEG A;  3U8N A;  3JAD A;  5HCM A;  5BRX A;  3SQ6 A;  2X00 A;  4UM3 A;  3U8K A;  4Z91 A;  3WTH A;  4ZRU A;  5KE4 A;  2XQ5 A;  2WZY A;  4B5D A;  2XNV A;  5SYO A;  3TLS A;  2WNJ A;  2XQ8 A;  5L4H A;  3WTK A;  4ZK4 A;  2XZ5 A;  3WTM A;  4TWF A;  3ZDH A;  5TVC A;  4IL4 A;  5J5I A;  2Y54 A;  5JME A;  3JAF A;  4IL9 A;  4X5T A;  3U8M A;  3UU5 A;  3P50 A;  2Y56 A;  2XQA A;  4LMJ A;  3WIP A;  4ZR6 A;  3UU4 A;  5HEO A;  4AFH A;  3ZDG A;  4AFG A;  5J5F A;  4QH5 A;  2PH9 A;  5AIN A;  4ILA A;  4NZB A;  5AFJ A;  4TNV A;  2C9T A;  4XK9 A;  5HEU A;  4LMK A;  1I9B A;  3GUA A;  4ZZC A;  3C79 A;  5BP0 A;  3TLU A; 
#chains in the Genus database with same CATH homology
 2XZ6 A;  3TLW A;  4PIR A;  3RHW A;  5J5H A;  3EHZ A;  5IUX A;  5J0Z A;  3WTO A;  2WNL A;  2Y58 A;  2BJ0 A;  4Z90 A;  4ILB A;  4HFB A;  4IRE A;  2ZJV A;  5CO5 A;  3UU8 A;  3UU3 A;  3WTL A;  2BYR A;  3TLT A;  4EZ1 A;  2VL0 A;  4ZJT A;  4UM3 P;  2ZJU A;  4WV9 A;  2XQ7 A;  2YME A;  2BYP A;  4NPP A;  3U8L A;  3UUB A;  1UW6 A;  4TNW A;  3WTJ A;  3ZKR A;  5AFK A;  4QAA A;  3UU6 A;  3RIA A;  5HCJ A;  5HEH A;  4ZK1 A;  2BYS A;  4TWD A;  3IGQ A;  5FJV A;  4LML A;  2YKS A;  2XQ3 A;  4UM3 S;  2QC1 B;  3T4M A;  3SH1 A;  3WTN A;  3PMZ A;  2XNT A;  4BFQ A;  4UXU A;  5KZU A;  4ZJS A;  2BR7 A;  4ZZB A;  2Y7Y A;  5L4E A;  4A98 A;  2X00 D;  3EAM A;  2WNC A;  4DBM A;  2BYN A;  3SQ9 A;  3SIO A;  4ILC A;  4UM1 A;  2XNU A;  4HQP A;  2YN6 A;  5L47 A;  4UY2 A;  5LG3 A;  4QAC A;  4BQT A;  3P4W A;  3C84 A;  2BYQ A;  2W8F A;  4HFE A;  2XQ6 A;  2BG9 E;  2XYT A;  3UQ4 A;  3WTI A;  4AFT A;  4QAB A;  2BG9 C;  2BG9 B;  4XHE A;  3U8J A;  2Y57 A;  2XYS A;  4QH1 A;  2YMD A;  5AFN A;  2BG9 A;  4HFI A;  4A97 A;  4D01 A;  3RQU A;  2PGZ A;  2XQ4 A;  4FRR A;  5AFH A;  5HEJ A;  3LSV A;  2UZ6 A;  5J5G A;  5BW2 A;  4TWH A;  5AFM B;  3PEO A;  1UX2 A;  2WN9 A;  1UV6 A;  3RIF A;  3RQW A;  5LXB A;  4COF A;  5AFL A;  4HFH A;  5AFM A;  2YOE A;  2XQ9 A;  4QH4 A;  3JAE A;  3TLV A;  4ALX A;  5CFB A;  4F8H A;  3EI0 A;  4HFD A;  2BR8 A;  3RI5 A;  3UQ7 A;  4HFC A;  2W8G A;  5HEG A;  3U8N A;  3JAD A;  5HCM A;  5BRX A;  3SQ6 A;  2X00 A;  4UM3 A;  3U8K A;  4Z91 A;  3WTH A;  4ZRU A;  5KE4 A;  2XQ5 A;  2WZY A;  4B5D A;  2XNV A;  5SYO A;  3TLS A;  2WNJ A;  2XQ8 A;  5L4H A;  3WTK A;  4ZK4 A;  2XZ5 A;  3WTM A;  4TWF A;  3ZDH A;  5TVC A;  4IL4 A;  5J5I A;  2Y54 A;  5JME A;  3JAF A;  4IL9 A;  4X5T A;  3U8M A;  3UU5 A;  3P50 A;  2Y56 A;  2XQA A;  4LMJ A;  3WIP A;  4ZR6 A;  3UU4 A;  5HEO A;  4AFH A;  3ZDG A;  4AFG A;  5J5F A;  4QH5 A;  2PH9 A;  5AIN A;  4ILA A;  4NZB A;  5AFJ A;  4TNV A;  2C9T A;  4XK9 A;  5HEU A;  4LMK A;  1I9B A;  3GUA A;  4ZZC A;  3C79 A;  5BP0 A;  3TLU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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