2YMEA

Crystal structure of a mutant binding protein (5htbp-achbp) in complex with granisetron
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
205
structure length
205
Chain Sequence
QANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKVDSSTNEVDLVYWERQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGVTCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Receptor
source organism Aplysia californica
publication title Structural Basis of Ligand Recognition in 5-Ht3 Receptors.
pubmed doi rcsb
molecule keywords SOLUBLE ACETYLCHOLINE RECEPTOR
total genus 47
structure length 205
sequence length 205
chains with identical sequence B, C, D, E, F, G, H, I, J
ec nomenclature
pdb deposition date 2012-10-09
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 2ymeA00
5HEUA 4LMKA 5HEGA 3U8NA 5LXBA 2Y54A 3C84A 4QACA 5J5GA 3UUBA 4HFIA 4ZK1A 2BG9A 3EAMA 4TNVA 3WIPA 3JAFA 3LSVA 3SIOA 5HCMA 2WNCA 2XZ5A 4ZZCA 2XQ9A 2YOEA 4BFQA 5LG3A 4WV9A 5HEJA 4ILCA 4TWHA 5J5FA 4AFGA 2BR7A 5HEOA 2W8GA 5TVCA 5L47A 2BYQA 2C9TA 2BYSA 3WTNA 3WTMA 2XQ8A 4HFBA 2WNLA 2YKSA 4ZR6A 5L4EA 4IL4A 3UQ4A 2Y57A 5AFMA 2WNJA 3T4MA 5CFBA 3ZDGA 4NZBA 2Y56A 2VL0A 2YMEA 5AFJA 3WTKA 3RIAA 5AFLA 4B5DA 2Y58A 4Z90A 2X00D 2XYSA 5CO5A 2X00A 5FJVA 3UU6A 2XQ4A 4UM3S 4QH5A 4UM3A 3JADA 4F8HA 2WZYA 3P4WA 5J5HA 2UZ6A 5BRXA 4ZZBA 2BJ0A 2BYNA 3GUAA 3SH1A 5JMEA 2BG9B 5AFKA 1I9BA 2XQ5A 4ZRUA 4HFHA 3RIFA 4AFHA 3C79A 4HQPA 3TLWA 3UU8A 3U8KA 3TLVA 5KE4A 4A97A 5HCJA 5L4HA 3JAEA 3PEOA 2PH9A 2XNTA 2ZJVA 5J0ZA 2BYPA 3RQWA 3ZKRA 4COFA 4UM1A 3RQUA 3TLSA 3WTOA 4FRRA 4ILBA 4TWDA 2XQ3A 4UXUA 3TLTA 5BW2A 3EHZA 2WN9A 1UW6A 4IL9A 4TNWA 4NPPA 3U8MA 4EZ1A 4DBMA 2ZJUA 2XQ7A 2XQ6A 2QC1B 2YN6A 4TWFA 5KZUA 3PMZA 4UM3P 5AFHA 4Z91A 2BYRA 4D01A 2BG9E 2BG9C 3ZDHA 4ALXA 5J5IA 2XNUA 3P50A 4ZK4A 4LMJA 4QH4A 4XK9A 2XQAA 4HFCA 2XNVA 2BR8A 3RHWA 3EI0A 4PIRA 4QABA 3WTJA 3U8JA 3U8LA 3SQ9A 4LMLA 4HFEA 3TLUA 4QH1A 3UU4A 4ZJTA 4AFTA 3UU5A 5AFMB 4XHEA 1UV6A 3UQ7A 5AFNA 3RI5A 3WTLA 3SQ6A 5HEHA 4ZJSA 5BP0A 3UU3A 5AINA 3WTHA 3IGQA 2PGZA 2XYTA 4UY2A 4X5TA 4A98A 5SYOA 2YMDA 4QAAA 1UX2A 2W8FA 4BQTA 5IUXA 4ILAA 4IREA 3WTIA 2XZ6A 2Y7YA 4HFDA
chains in the Genus database with same CATH superfamily
5HEUA 4LMKA 5HEGA 3U8NA 5LXBA 2Y54A 3C84A 4QACA 5J5GA 3UUBA 4HFIA 4ZK1A 2BG9A 3EAMA 4TNVA 3WIPA 3JAFA 3LSVA 3SIOA 5HCMA 2WNCA 2XZ5A 4ZZCA 2XQ9A 2YOEA 4BFQA 5LG3A 4WV9A 5HEJA 4ILCA 4TWHA 5J5FA 4AFGA 2BR7A 5HEOA 2W8GA 5TVCA 5L47A 2BYQA 2C9TA 2BYSA 3WTNA 3WTMA 2XQ8A 4HFBA 2WNLA 2YKSA 4ZR6A 5L4EA 4IL4A 3UQ4A 2Y57A 5AFMA 2WNJA 3T4MA 5CFBA 3ZDGA 4NZBA 2Y56A 2VL0A 2YMEA 5AFJA 3WTKA 3RIAA 5AFLA 4B5DA 2Y58A 4Z90A 2X00D 2XYSA 5CO5A 2X00A 5FJVA 3UU6A 2XQ4A 4UM3S 4QH5A 4UM3A 3JADA 4F8HA 2WZYA 3P4WA 5J5HA 2UZ6A 5BRXA 4ZZBA 2BJ0A 2BYNA 3GUAA 3SH1A 5JMEA 2BG9B 5AFKA 1I9BA 2XQ5A 4ZRUA 4HFHA 3RIFA 4AFHA 3C79A 4HQPA 3TLWA 3UU8A 3U8KA 3TLVA 5KE4A 4A97A 5HCJA 5L4HA 3JAEA 3PEOA 2PH9A 2XNTA 2ZJVA 5J0ZA 2BYPA 3RQWA 3ZKRA 4COFA 4UM1A 3RQUA 3TLSA 3WTOA 4FRRA 4ILBA 4TWDA 2XQ3A 4UXUA 3TLTA 5BW2A 3EHZA 2WN9A 1UW6A 4IL9A 4TNWA 4NPPA 3U8MA 4EZ1A 4DBMA 2ZJUA 2XQ7A 2XQ6A 2QC1B 2YN6A 4TWFA 5KZUA 3PMZA 4UM3P 5AFHA 4Z91A 2BYRA 4D01A 2BG9E 2BG9C 3ZDHA 4ALXA 5J5IA 2XNUA 3P50A 4ZK4A 4LMJA 4QH4A 4XK9A 2XQAA 4HFCA 2XNVA 2BR8A 3RHWA 3EI0A 4PIRA 4QABA 3WTJA 3U8JA 3U8LA 3SQ9A 4LMLA 4HFEA 3TLUA 4QH1A 3UU4A 4ZJTA 4AFTA 3UU5A 5AFMB 4XHEA 1UV6A 3UQ7A 5AFNA 3RI5A 3WTLA 3SQ6A 5HEHA 4ZJSA 5BP0A 3UU3A 5AINA 3WTHA 3IGQA 2PGZA 2XYTA 4UY2A 4X5TA 4A98A 5SYOA 2YMDA 4QAAA 1UX2A 2W8FA 4BQTA 5IUXA 4ILAA 4IREA 3WTIA 2XZ6A 2Y7YA 4HFDA
chains in the Genus database with same CATH topology
5HEUA 4LMKA 5HEGA 3U8NA 5LXBA 2Y54A 3C84A 4QACA 5J5GA 3UUBA 4HFIA 4ZK1A 2BG9A 3EAMA 4TNVA 3WIPA 3JAFA 3LSVA 3SIOA 5HCMA 2WNCA 2XZ5A 4ZZCA 2XQ9A 2YOEA 4BFQA 5LG3A 4WV9A 5HEJA 4ILCA 4TWHA 5J5FA 4AFGA 2BR7A 5HEOA 2W8GA 5TVCA 5L47A 2BYQA 2C9TA 2BYSA 3WTNA 3WTMA 2XQ8A 4HFBA 2WNLA 2YKSA 4ZR6A 5L4EA 4IL4A 3UQ4A 2Y57A 5AFMA 2WNJA 3T4MA 5CFBA 3ZDGA 4NZBA 2Y56A 2VL0A 2YMEA 5AFJA 3WTKA 3RIAA 5AFLA 4B5DA 2Y58A 4Z90A 2X00D 2XYSA 5CO5A 2X00A 5FJVA 3UU6A 2XQ4A 4UM3S 4QH5A 4UM3A 3JADA 4F8HA 2WZYA 3P4WA 5J5HA 2UZ6A 5BRXA 4ZZBA 2BJ0A 2BYNA 3GUAA 3SH1A 5JMEA 2BG9B 5AFKA 1I9BA 2XQ5A 4ZRUA 4HFHA 3RIFA 4AFHA 3C79A 4HQPA 3TLWA 3UU8A 3U8KA 3TLVA 5KE4A 4A97A 5HCJA 5L4HA 3JAEA 3PEOA 2PH9A 2XNTA 2ZJVA 5J0ZA 2BYPA 3RQWA 3ZKRA 4COFA 4UM1A 3RQUA 3TLSA 3WTOA 4FRRA 4ILBA 4TWDA 2XQ3A 4UXUA 3TLTA 5BW2A 3EHZA 2WN9A 1UW6A 4IL9A 4TNWA 4NPPA 3U8MA 4EZ1A 4DBMA 2ZJUA 2XQ7A 2XQ6A 2QC1B 2YN6A 4TWFA 5KZUA 3PMZA 4UM3P 5AFHA 4Z91A 2BYRA 4D01A 2BG9E 2BG9C 3ZDHA 4ALXA 5J5IA 2XNUA 3P50A 4ZK4A 4LMJA 4QH4A 4XK9A 2XQAA 4HFCA 2XNVA 2BR8A 3RHWA 3EI0A 4PIRA 4QABA 3WTJA 3U8JA 3U8LA 3SQ9A 4LMLA 4HFEA 3TLUA 4QH1A 3UU4A 4ZJTA 4AFTA 3UU5A 5AFMB 4XHEA 1UV6A 3UQ7A 5AFNA 3RI5A 3WTLA 3SQ6A 5HEHA 4ZJSA 5BP0A 3UU3A 5AINA 3WTHA 3IGQA 2PGZA 2XYTA 4UY2A 4X5TA 4A98A 5SYOA 2YMDA 4QAAA 1UX2A 2W8FA 4BQTA 5IUXA 4ILAA 4IREA 3WTIA 2XZ6A 2Y7YA 4HFDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HEU A;  4LMK A;  5HEG A;  3U8N A;  5LXB A;  2Y54 A;  3C84 A;  4QAC A;  5J5G A;  3UUB A;  4HFI A;  4ZK1 A;  2BG9 A;  3EAM A;  4TNV A;  3WIP A;  3JAF A;  3LSV A;  3SIO A;  5HCM A;  2WNC A;  2XZ5 A;  4ZZC A;  2XQ9 A;  2YOE A;  4BFQ A;  5LG3 A;  4WV9 A;  5HEJ A;  4ILC A;  4TWH A;  5J5F A;  4AFG A;  2BR7 A;  5HEO A;  2W8G A;  5TVC A;  5L47 A;  2BYQ A;  2C9T A;  2BYS A;  3WTN A;  3WTM A;  2XQ8 A;  4HFB A;  2WNL A;  2YKS A;  4ZR6 A;  5L4E A;  4IL4 A;  3UQ4 A;  2Y57 A;  5AFM A;  2WNJ A;  3T4M A;  5CFB A;  3ZDG A;  4NZB A;  2Y56 A;  2VL0 A;  2YME A;  5AFJ A;  3WTK A;  3RIA A;  5AFL A;  4B5D A;  2Y58 A;  4Z90 A;  2X00 D;  2XYS A;  5CO5 A;  2X00 A;  5FJV A;  3UU6 A;  2XQ4 A;  4UM3 S;  4QH5 A;  4UM3 A;  3JAD A;  4F8H A;  2WZY A;  3P4W A;  5J5H A;  2UZ6 A;  5BRX A;  4ZZB A;  2BJ0 A;  2BYN A;  3GUA A;  3SH1 A;  5JME A;  2BG9 B;  5AFK A;  1I9B A;  2XQ5 A;  4ZRU A;  4HFH A;  3RIF A;  4AFH A;  3C79 A;  4HQP A;  3TLW A;  3UU8 A;  3U8K A;  3TLV A;  5KE4 A;  4A97 A;  5HCJ A;  5L4H A;  3JAE A;  3PEO A;  2PH9 A;  2XNT A;  2ZJV A;  5J0Z A;  2BYP A;  3RQW A;  3ZKR A;  4COF A;  4UM1 A;  3RQU A;  3TLS A;  3WTO A;  4FRR A;  4ILB A;  4TWD A;  2XQ3 A;  4UXU A;  3TLT A;  5BW2 A;  3EHZ A;  2WN9 A;  1UW6 A;  4IL9 A;  4TNW A;  4NPP A;  3U8M A;  4EZ1 A;  4DBM A;  2ZJU A;  2XQ7 A;  2XQ6 A;  2QC1 B;  2YN6 A;  4TWF A;  5KZU A;  3PMZ A;  4UM3 P;  5AFH A;  4Z91 A;  2BYR A;  4D01 A;  2BG9 E;  2BG9 C;  3ZDH A;  4ALX A;  5J5I A;  2XNU A;  3P50 A;  4ZK4 A;  4LMJ A;  4QH4 A;  4XK9 A;  2XQA A;  4HFC A;  2XNV A;  2BR8 A;  3RHW A;  3EI0 A;  4PIR A;  4QAB A;  3WTJ A;  3U8J A;  3U8L A;  3SQ9 A;  4LML A;  4HFE A;  3TLU A;  4QH1 A;  3UU4 A;  4ZJT A;  4AFT A;  3UU5 A;  5AFM B;  4XHE A;  1UV6 A;  3UQ7 A;  5AFN A;  3RI5 A;  3WTL A;  3SQ6 A;  5HEH A;  4ZJS A;  5BP0 A;  3UU3 A;  5AIN A;  3WTH A;  3IGQ A;  2PGZ A;  2XYT A;  4UY2 A;  4X5T A;  4A98 A;  5SYO A;  2YMD A;  4QAA A;  1UX2 A;  2W8F A;  4BQT A;  5IUX A;  4ILA A;  4IRE A;  3WTI A;  2XZ6 A;  2Y7Y A;  4HFD A; 
#chains in the Genus database with same CATH topology
 5HEU A;  4LMK A;  5HEG A;  3U8N A;  5LXB A;  2Y54 A;  3C84 A;  4QAC A;  5J5G A;  3UUB A;  4HFI A;  4ZK1 A;  2BG9 A;  3EAM A;  4TNV A;  3WIP A;  3JAF A;  3LSV A;  3SIO A;  5HCM A;  2WNC A;  2XZ5 A;  4ZZC A;  2XQ9 A;  2YOE A;  4BFQ A;  5LG3 A;  4WV9 A;  5HEJ A;  4ILC A;  4TWH A;  5J5F A;  4AFG A;  2BR7 A;  5HEO A;  2W8G A;  5TVC A;  5L47 A;  2BYQ A;  2C9T A;  2BYS A;  3WTN A;  3WTM A;  2XQ8 A;  4HFB A;  2WNL A;  2YKS A;  4ZR6 A;  5L4E A;  4IL4 A;  3UQ4 A;  2Y57 A;  5AFM A;  2WNJ A;  3T4M A;  5CFB A;  3ZDG A;  4NZB A;  2Y56 A;  2VL0 A;  2YME A;  5AFJ A;  3WTK A;  3RIA A;  5AFL A;  4B5D A;  2Y58 A;  4Z90 A;  2X00 D;  2XYS A;  5CO5 A;  2X00 A;  5FJV A;  3UU6 A;  2XQ4 A;  4UM3 S;  4QH5 A;  4UM3 A;  3JAD A;  4F8H A;  2WZY A;  3P4W A;  5J5H A;  2UZ6 A;  5BRX A;  4ZZB A;  2BJ0 A;  2BYN A;  3GUA A;  3SH1 A;  5JME A;  2BG9 B;  5AFK A;  1I9B A;  2XQ5 A;  4ZRU A;  4HFH A;  3RIF A;  4AFH A;  3C79 A;  4HQP A;  3TLW A;  3UU8 A;  3U8K A;  3TLV A;  5KE4 A;  4A97 A;  5HCJ A;  5L4H A;  3JAE A;  3PEO A;  2PH9 A;  2XNT A;  2ZJV A;  5J0Z A;  2BYP A;  3RQW A;  3ZKR A;  4COF A;  4UM1 A;  3RQU A;  3TLS A;  3WTO A;  4FRR A;  4ILB A;  4TWD A;  2XQ3 A;  4UXU A;  3TLT A;  5BW2 A;  3EHZ A;  2WN9 A;  1UW6 A;  4IL9 A;  4TNW A;  4NPP A;  3U8M A;  4EZ1 A;  4DBM A;  2ZJU A;  2XQ7 A;  2XQ6 A;  2QC1 B;  2YN6 A;  4TWF A;  5KZU A;  3PMZ A;  4UM3 P;  5AFH A;  4Z91 A;  2BYR A;  4D01 A;  2BG9 E;  2BG9 C;  3ZDH A;  4ALX A;  5J5I A;  2XNU A;  3P50 A;  4ZK4 A;  4LMJ A;  4QH4 A;  4XK9 A;  2XQA A;  4HFC A;  2XNV A;  2BR8 A;  3RHW A;  3EI0 A;  4PIR A;  4QAB A;  3WTJ A;  3U8J A;  3U8L A;  3SQ9 A;  4LML A;  4HFE A;  3TLU A;  4QH1 A;  3UU4 A;  4ZJT A;  4AFT A;  3UU5 A;  5AFM B;  4XHE A;  1UV6 A;  3UQ7 A;  5AFN A;  3RI5 A;  3WTL A;  3SQ6 A;  5HEH A;  4ZJS A;  5BP0 A;  3UU3 A;  5AIN A;  3WTH A;  3IGQ A;  2PGZ A;  2XYT A;  4UY2 A;  4X5T A;  4A98 A;  5SYO A;  2YMD A;  4QAA A;  1UX2 A;  2W8F A;  4BQT A;  5IUX A;  4ILA A;  4IRE A;  3WTI A;  2XZ6 A;  2Y7Y A;  4HFD A; 
#chains in the Genus database with same CATH homology
 5HEU A;  4LMK A;  5HEG A;  3U8N A;  5LXB A;  2Y54 A;  3C84 A;  4QAC A;  5J5G A;  3UUB A;  4HFI A;  4ZK1 A;  2BG9 A;  3EAM A;  4TNV A;  3WIP A;  3JAF A;  3LSV A;  3SIO A;  5HCM A;  2WNC A;  2XZ5 A;  4ZZC A;  2XQ9 A;  2YOE A;  4BFQ A;  5LG3 A;  4WV9 A;  5HEJ A;  4ILC A;  4TWH A;  5J5F A;  4AFG A;  2BR7 A;  5HEO A;  2W8G A;  5TVC A;  5L47 A;  2BYQ A;  2C9T A;  2BYS A;  3WTN A;  3WTM A;  2XQ8 A;  4HFB A;  2WNL A;  2YKS A;  4ZR6 A;  5L4E A;  4IL4 A;  3UQ4 A;  2Y57 A;  5AFM A;  2WNJ A;  3T4M A;  5CFB A;  3ZDG A;  4NZB A;  2Y56 A;  2VL0 A;  2YME A;  5AFJ A;  3WTK A;  3RIA A;  5AFL A;  4B5D A;  2Y58 A;  4Z90 A;  2X00 D;  2XYS A;  5CO5 A;  2X00 A;  5FJV A;  3UU6 A;  2XQ4 A;  4UM3 S;  4QH5 A;  4UM3 A;  3JAD A;  4F8H A;  2WZY A;  3P4W A;  5J5H A;  2UZ6 A;  5BRX A;  4ZZB A;  2BJ0 A;  2BYN A;  3GUA A;  3SH1 A;  5JME A;  2BG9 B;  5AFK A;  1I9B A;  2XQ5 A;  4ZRU A;  4HFH A;  3RIF A;  4AFH A;  3C79 A;  4HQP A;  3TLW A;  3UU8 A;  3U8K A;  3TLV A;  5KE4 A;  4A97 A;  5HCJ A;  5L4H A;  3JAE A;  3PEO A;  2PH9 A;  2XNT A;  2ZJV A;  5J0Z A;  2BYP A;  3RQW A;  3ZKR A;  4COF A;  4UM1 A;  3RQU A;  3TLS A;  3WTO A;  4FRR A;  4ILB A;  4TWD A;  2XQ3 A;  4UXU A;  3TLT A;  5BW2 A;  3EHZ A;  2WN9 A;  1UW6 A;  4IL9 A;  4TNW A;  4NPP A;  3U8M A;  4EZ1 A;  4DBM A;  2ZJU A;  2XQ7 A;  2XQ6 A;  2QC1 B;  2YN6 A;  4TWF A;  5KZU A;  3PMZ A;  4UM3 P;  5AFH A;  4Z91 A;  2BYR A;  4D01 A;  2BG9 E;  2BG9 C;  3ZDH A;  4ALX A;  5J5I A;  2XNU A;  3P50 A;  4ZK4 A;  4LMJ A;  4QH4 A;  4XK9 A;  2XQA A;  4HFC A;  2XNV A;  2BR8 A;  3RHW A;  3EI0 A;  4PIR A;  4QAB A;  3WTJ A;  3U8J A;  3U8L A;  3SQ9 A;  4LML A;  4HFE A;  3TLU A;  4QH1 A;  3UU4 A;  4ZJT A;  4AFT A;  3UU5 A;  5AFM B;  4XHE A;  1UV6 A;  3UQ7 A;  5AFN A;  3RI5 A;  3WTL A;  3SQ6 A;  5HEH A;  4ZJS A;  5BP0 A;  3UU3 A;  5AIN A;  3WTH A;  3IGQ A;  2PGZ A;  2XYT A;  4UY2 A;  4X5T A;  4A98 A;  5SYO A;  2YMD A;  4QAA A;  1UX2 A;  2W8F A;  4BQT A;  5IUX A;  4ILA A;  4IRE A;  3WTI A;  2XZ6 A;  2Y7Y A;  4HFD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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