3C84 | Genus

Total Genus 52

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	52
sequence length	210
structure length	210
Chain Sequence	DKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Choline-binding protein
source organism	Aplysia californica
publication title	Atomic interactions of neonicotinoid agonists with AChBP: molecular recognition of the distinctive electronegative pharmacophore. pubmed doi rcsb
molecule keywords	Soluble acetylcholine receptor
total genus	52
structure length	210
sequence length	210
chains with identical sequence	B, C, D, E
ec nomenclature
pdb deposition date	2008-02-08

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF02931	Neur_chan_LBD	Neurotransmitter-gated ion-channel ligand binding domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.70.170.10	Mainly Beta	Distorted Sandwich	Acetylcholine Binding Protein; Chain: A,	Neurotransmitter-gated ion-channel ligand-binding domain	3c84A00

2Y54A 5IUXA 3WTJA 3WTKA 2XQ7A 2BYSA 3ZDHA 4ZJTA 3C84A 4HFBA 5BW2A 4TWFA 4UM3S 4QH5A 5HEJA 4TNVA 5HCJA 5AFHA 2BYRA 2WN9A 3WTNA 3RHWA 3JAEA 4IREA 2BYQA 3JADA 4QABA 5CO5A 2XZ5A 2XZ6A 4NPPA 2WNCA 3RQUA 3RQWA 2PGZA 2BG9E 5HEHA 2W8FA 4LMLA 2YN6A 4IL4A 2X00A 2ZJUA 4ILBA 4IL9A 3TLSA 4AFGA 3LSVA 4UM1A 5J5FA 4ZK4A 2YMEA 2BR8A 4HFEA 4D01A 5HEOA 1I9BA 2XNUA 3SIOA 3TLWA 2Y56A 4ZZBA 5LXBA 4ZR6A 2YKSA 5KE4A 4TWDA 4QACA 2BG9A 3UU6A 3ZDGA 4HFHA 3U8KA 4ZK1A 4UM3A 3U8MA 2ZJVA 1UW6A 4TWHA 3RI5A 3RIAA 2QC1B 3UUBA 5CFBA 4LMKA 3U8JA 2Y58A 4QH1A 4ZZCA 3WTOA 5AFLA 2WZYA 2XNVA 5J5IA 3SH1A 4NZBA 4XHEA 5LG3A 3UQ7A 3EI0A 4LMJA 1UV6A 3UU3A 4AFTA 5L47A 4WV9A 3UU4A 4HQPA 3EAMA 4AFHA 3U8NA 4QH4A 2BYPA 4UY2A 5AFMB 3EHZA 5AFNA 3UU5A 4ALXA 4X5TA 4Z90A 3WTHA 2VL0A 3SQ9A 2PH9A 2XQ9A 5TVCA 2XNTA 3ZKRA 4QAAA 5HEUA 2WNLA 2BJ0A 3P50A 4UM3P 5BRXA 3PEOA 5J0ZA 4XK9A 1UX2A 4HFCA 5JMEA 2WNJA 5SYOA 3JAFA 2XQAA 3UQ4A 2BYNA 5HCMA 3T4MA 3IGQA 2XYSA 4ILAA 4HFIA 4B5DA 3SQ6A 2XQ5A 4TNWA 3WTLA 5AFKA 2Y57A 2BG9B 4HFDA 2BG9C 4EZ1A 5L4EA 2UZ6A 4A98A 3UU8A 4DBMA 2XQ6A 5FJVA 2BR7A 2YMDA 3C79A 4A97A 4Z91A 5AINA 3GUAA 3WIPA 4ZRUA 3P4WA 5L4HA 5AFMA 5J5HA 3RIFA 4BFQA 2XYTA 3WTIA 3TLUA 2XQ8A 3WTMA 2Y7YA 5BP0A 5J5GA 3U8LA 4FRRA 2W8GA 4ILCA 2X00D 4COFA 4PIRA 2XQ4A 5KZUA 2C9TA 4UXUA 5AFJA 5HEGA 2XQ3A 3PMZA 3TLTA 3TLVA 4ZJSA 4BQTA 4F8HA 2YOEA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 2Y54 A;  5IUX A;  3WTJ A;  3WTK A;  2XQ7 A;  2BYS A;  3ZDH A;  4ZJT A;  3C84 A;  4HFB A;  5BW2 A;  4TWF A;  4UM3 S;  4QH5 A;  5HEJ A;  4TNV A;  5HCJ A;  5AFH A;  2BYR A;  2WN9 A;  3WTN A;  3RHW A;  3JAE A;  4IRE A;  2BYQ A;  3JAD A;  4QAB A;  5CO5 A;  2XZ5 A;  2XZ6 A;  4NPP A;  2WNC A;  3RQU A;  3RQW A;  2PGZ A;  2BG9 E;  5HEH A;  2W8F A;  4LML A;  2YN6 A;  4IL4 A;  2X00 A;  2ZJU A;  4ILB A;  4IL9 A;  3TLS A;  4AFG A;  3LSV A;  4UM1 A;  5J5F A;  4ZK4 A;  2YME A;  2BR8 A;  4HFE A;  4D01 A;  5HEO A;  1I9B A;  2XNU A;  3SIO A;  3TLW A;  2Y56 A;  4ZZB A;  5LXB A;  4ZR6 A;  2YKS A;  5KE4 A;  4TWD A;  4QAC A;  2BG9 A;  3UU6 A;  3ZDG A;  4HFH A;  3U8K A;  4ZK1 A;  4UM3 A;  3U8M A;  2ZJV A;  1UW6 A;  4TWH A;  3RI5 A;  3RIA A;  2QC1 B;  3UUB A;  5CFB A;  4LMK A;  3U8J A;  2Y58 A;  4QH1 A;  4ZZC A;  3WTO A;  5AFL A;  2WZY A;  2XNV A;  5J5I A;  3SH1 A;  4NZB A;  4XHE A;  5LG3 A;  3UQ7 A;  3EI0 A;  4LMJ A;  1UV6 A;  3UU3 A;  4AFT A;  5L47 A;  4WV9 A;  3UU4 A;  4HQP A;  3EAM A;  4AFH A;  3U8N A;  4QH4 A;  2BYP A;  4UY2 A;  5AFM B;  3EHZ A;  5AFN A;  3UU5 A;  4ALX A;  4X5T A;  4Z90 A;  3WTH A;  2VL0 A;  3SQ9 A;  2PH9 A;  2XQ9 A;  5TVC A;  2XNT A;  3ZKR A;  4QAA A;  5HEU A;  2WNL A;  2BJ0 A;  3P50 A;  4UM3 P;  5BRX A;  3PEO A;  5J0Z A;  4XK9 A;  1UX2 A;  4HFC A;  5JME A;  2WNJ A;  5SYO A;  3JAF A;  2XQA A;  3UQ4 A;  2BYN A;  5HCM A;  3T4M A;  3IGQ A;  2XYS A;  4ILA A;  4HFI A;  4B5D A;  3SQ6 A;  2XQ5 A;  4TNW A;  3WTL A;  5AFK A;  2Y57 A;  2BG9 B;  4HFD A;  2BG9 C;  4EZ1 A;  5L4E A;  2UZ6 A;  4A98 A;  3UU8 A;  4DBM A;  2XQ6 A;  5FJV A;  2BR7 A;  2YMD A;  3C79 A;  4A97 A;  4Z91 A;  5AIN A;  3GUA A;  3WIP A;  4ZRU A;  3P4W A;  5L4H A;  5AFM A;  5J5H A;  3RIF A;  4BFQ A;  2XYT A;  3WTI A;  3TLU A;  2XQ8 A;  3WTM A;  2Y7Y A;  5BP0 A;  5J5G A;  3U8L A;  4FRR A;  2W8G A;  4ILC A;  2X00 D;  4COF A;  4PIR A;  2XQ4 A;  5KZU A;  2C9T A;  4UXU A;  5AFJ A;  5HEG A;  2XQ3 A;  3PMZ A;  3TLT A;  3TLV A;  4ZJS A;  4BQT A;  4F8H A;  2YOE A; 
#chains in the Genus database with same CATH topology
 2Y54 A;  5IUX A;  3WTJ A;  3WTK A;  2XQ7 A;  2BYS A;  3ZDH A;  4ZJT A;  3C84 A;  4HFB A;  5BW2 A;  4TWF A;  4UM3 S;  4QH5 A;  5HEJ A;  4TNV A;  5HCJ A;  5AFH A;  2BYR A;  2WN9 A;  3WTN A;  3RHW A;  3JAE A;  4IRE A;  2BYQ A;  3JAD A;  4QAB A;  5CO5 A;  2XZ5 A;  2XZ6 A;  4NPP A;  2WNC A;  3RQU A;  3RQW A;  2PGZ A;  2BG9 E;  5HEH A;  2W8F A;  4LML A;  2YN6 A;  4IL4 A;  2X00 A;  2ZJU A;  4ILB A;  4IL9 A;  3TLS A;  4AFG A;  3LSV A;  4UM1 A;  5J5F A;  4ZK4 A;  2YME A;  2BR8 A;  4HFE A;  4D01 A;  5HEO A;  1I9B A;  2XNU A;  3SIO A;  3TLW A;  2Y56 A;  4ZZB A;  5LXB A;  4ZR6 A;  2YKS A;  5KE4 A;  4TWD A;  4QAC A;  2BG9 A;  3UU6 A;  3ZDG A;  4HFH A;  3U8K A;  4ZK1 A;  4UM3 A;  3U8M A;  2ZJV A;  1UW6 A;  4TWH A;  3RI5 A;  3RIA A;  2QC1 B;  3UUB A;  5CFB A;  4LMK A;  3U8J A;  2Y58 A;  4QH1 A;  4ZZC A;  3WTO A;  5AFL A;  2WZY A;  2XNV A;  5J5I A;  3SH1 A;  4NZB A;  4XHE A;  5LG3 A;  3UQ7 A;  3EI0 A;  4LMJ A;  1UV6 A;  3UU3 A;  4AFT A;  5L47 A;  4WV9 A;  3UU4 A;  4HQP A;  3EAM A;  4AFH A;  3U8N A;  4QH4 A;  2BYP A;  4UY2 A;  5AFM B;  3EHZ A;  5AFN A;  3UU5 A;  4ALX A;  4X5T A;  4Z90 A;  3WTH A;  2VL0 A;  3SQ9 A;  2PH9 A;  2XQ9 A;  5TVC A;  2XNT A;  3ZKR A;  4QAA A;  5HEU A;  2WNL A;  2BJ0 A;  3P50 A;  4UM3 P;  5BRX A;  3PEO A;  5J0Z A;  4XK9 A;  1UX2 A;  4HFC A;  5JME A;  2WNJ A;  5SYO A;  3JAF A;  2XQA A;  3UQ4 A;  2BYN A;  5HCM A;  3T4M A;  3IGQ A;  2XYS A;  4ILA A;  4HFI A;  4B5D A;  3SQ6 A;  2XQ5 A;  4TNW A;  3WTL A;  5AFK A;  2Y57 A;  2BG9 B;  4HFD A;  2BG9 C;  4EZ1 A;  5L4E A;  2UZ6 A;  4A98 A;  3UU8 A;  4DBM A;  2XQ6 A;  5FJV A;  2BR7 A;  2YMD A;  3C79 A;  4A97 A;  4Z91 A;  5AIN A;  3GUA A;  3WIP A;  4ZRU A;  3P4W A;  5L4H A;  5AFM A;  5J5H A;  3RIF A;  4BFQ A;  2XYT A;  3WTI A;  3TLU A;  2XQ8 A;  3WTM A;  2Y7Y A;  5BP0 A;  5J5G A;  3U8L A;  4FRR A;  2W8G A;  4ILC A;  2X00 D;  4COF A;  4PIR A;  2XQ4 A;  5KZU A;  2C9T A;  4UXU A;  5AFJ A;  5HEG A;  2XQ3 A;  3PMZ A;  3TLT A;  3TLV A;  4ZJS A;  4BQT A;  4F8H A;  2YOE A; 
#chains in the Genus database with same CATH homology
 2Y54 A;  5IUX A;  3WTJ A;  3WTK A;  2XQ7 A;  2BYS A;  3ZDH A;  4ZJT A;  3C84 A;  4HFB A;  5BW2 A;  4TWF A;  4UM3 S;  4QH5 A;  5HEJ A;  4TNV A;  5HCJ A;  5AFH A;  2BYR A;  2WN9 A;  3WTN A;  3RHW A;  3JAE A;  4IRE A;  2BYQ A;  3JAD A;  4QAB A;  5CO5 A;  2XZ5 A;  2XZ6 A;  4NPP A;  2WNC A;  3RQU A;  3RQW A;  2PGZ A;  2BG9 E;  5HEH A;  2W8F A;  4LML A;  2YN6 A;  4IL4 A;  2X00 A;  2ZJU A;  4ILB A;  4IL9 A;  3TLS A;  4AFG A;  3LSV A;  4UM1 A;  5J5F A;  4ZK4 A;  2YME A;  2BR8 A;  4HFE A;  4D01 A;  5HEO A;  1I9B A;  2XNU A;  3SIO A;  3TLW A;  2Y56 A;  4ZZB A;  5LXB A;  4ZR6 A;  2YKS A;  5KE4 A;  4TWD A;  4QAC A;  2BG9 A;  3UU6 A;  3ZDG A;  4HFH A;  3U8K A;  4ZK1 A;  4UM3 A;  3U8M A;  2ZJV A;  1UW6 A;  4TWH A;  3RI5 A;  3RIA A;  2QC1 B;  3UUB A;  5CFB A;  4LMK A;  3U8J A;  2Y58 A;  4QH1 A;  4ZZC A;  3WTO A;  5AFL A;  2WZY A;  2XNV A;  5J5I A;  3SH1 A;  4NZB A;  4XHE A;  5LG3 A;  3UQ7 A;  3EI0 A;  4LMJ A;  1UV6 A;  3UU3 A;  4AFT A;  5L47 A;  4WV9 A;  3UU4 A;  4HQP A;  3EAM A;  4AFH A;  3U8N A;  4QH4 A;  2BYP A;  4UY2 A;  5AFM B;  3EHZ A;  5AFN A;  3UU5 A;  4ALX A;  4X5T A;  4Z90 A;  3WTH A;  2VL0 A;  3SQ9 A;  2PH9 A;  2XQ9 A;  5TVC A;  2XNT A;  3ZKR A;  4QAA A;  5HEU A;  2WNL A;  2BJ0 A;  3P50 A;  4UM3 P;  5BRX A;  3PEO A;  5J0Z A;  4XK9 A;  1UX2 A;  4HFC A;  5JME A;  2WNJ A;  5SYO A;  3JAF A;  2XQA A;  3UQ4 A;  2BYN A;  5HCM A;  3T4M A;  3IGQ A;  2XYS A;  4ILA A;  4HFI A;  4B5D A;  3SQ6 A;  2XQ5 A;  4TNW A;  3WTL A;  5AFK A;  2Y57 A;  2BG9 B;  4HFD A;  2BG9 C;  4EZ1 A;  5L4E A;  2UZ6 A;  4A98 A;  3UU8 A;  4DBM A;  2XQ6 A;  5FJV A;  2BR7 A;  2YMD A;  3C79 A;  4A97 A;  4Z91 A;  5AIN A;  3GUA A;  3WIP A;  4ZRU A;  3P4W A;  5L4H A;  5AFM A;  5J5H A;  3RIF A;  4BFQ A;  2XYT A;  3WTI A;  3TLU A;  2XQ8 A;  3WTM A;  2Y7Y A;  5BP0 A;  5J5G A;  3U8L A;  4FRR A;  2W8G A;  4ILC A;  2X00 D;  4COF A;  4PIR A;  2XQ4 A;  5KZU A;  2C9T A;  4UXU A;  5AFJ A;  5HEG A;  2XQ3 A;  3PMZ A;  3TLT A;  3TLV A;  4ZJS A;  4BQT A;  4F8H A;  2YOE A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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3C84A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations