3C84A

Crystal structure of a complex of achbp from aplysia californica and the neonicotinoid thiacloprid
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
210
structure length
210
Chain Sequence
DKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Atomic interactions of neonicotinoid agonists with AChBP: molecular recognition of the distinctive electronegative pharmacophore.
pubmed doi rcsb
molecule tags Choline-binding protein
source organism Aplysia californica
molecule keywords Soluble acetylcholine receptor
total genus 52
structure length 210
sequence length 210
chains with identical sequence B, C, D, E
ec nomenclature
pdb deposition date 2008-02-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 3c84A00
4ZRUA 3WTIA 5LG3A 4Z90A 5L47A 4ALXA 3SIOA 3SQ6A 3UU5A 3RHWA 2Y56A 5IUXA 5HCJA 2BR7A 2XYSA 3UQ4A 4ZZCA 2VL0A 2XQ4A 4COFA 3SH1A 4HFHA 5L4HA 3U8NA 3TLUA 2XNVA 2XZ6A 2BJ0A 1I9BA 3UU8A 3EAMA 4QH4A 3WTJA 3U8LA 3C84A 4UM3S 5HEHA 2BYRA 4ZK1A 2C9TA 2XYTA 2XZ5A 4IREA 4TNWA 4QH5A 5AFLA 2YKSA 5FJVA 2BYPA 4A98A 4TWDA 2W8FA 3UQ7A 5JMEA 2UZ6A 3TLWA 3UU4A 4BQTA 4IL4A 3P4WA 5AFKA 5J5GA 3UUBA 4IL9A 4ILCA 3WTKA 5LXBA 3JADA 5BP0A 5CO5A 3WTHA 4HFDA 4ZR6A 4AFHA 2XNUA 2QC1B 4LMLA 3GUAA 4AFTA 4B5DA 2YMEA 4HFEA 4PIRA 2BYSA 4UY2A 4HFBA 5AFNA 4DBMA 4ILBA 2Y58A 3PMZA 4QH1A 3WTOA 5KE4A 2Y57A 2YMDA 4HFCA 5TVCA 3C79A 3U8JA 3ZKRA 1UV6A 2WZYA 2PH9A 4ZJSA 5J5FA 5BW2A 4AFGA 3T4MA 4HFIA 4QABA 2X00D 2WNLA 2XQAA 3PEOA 5HEGA 3WIPA 2BG9C 4NZBA 3JAEA 4X5TA 3ZDHA 3U8MA 3JAFA 4BFQA 5AFMB 2Y54A 3RQWA 2WNJA 5CFBA 1UW6A 4LMJA 4ILAA 3WTMA 4UM3P 3UU3A 2YOEA 5J0ZA 2X00A 3RQUA 4QACA 5AFHA 4WV9A 3RIAA 4HQPA 4F8HA 2XQ6A 4XK9A 2BR8A 3EHZA 4D01A 3TLTA 5HEOA 3WTLA 3RI5A 3ZDGA 5AFMA 2XQ3A 5L4EA 4UM1A 3RIFA 4ZJTA 2XQ9A 2BYNA 2XQ7A 3TLSA 2W8GA 2XNTA 5J5IA 2WNCA 5HEUA 3P50A 4A97A 4Z91A 4QAAA 2YN6A 4LMKA 2WN9A 2BG9B 3TLVA 3UU6A 4UXUA 2ZJVA 3WTNA 5AFJA 2PGZA 2XQ5A 2ZJUA 4EZ1A 5KZUA 5HEJA 3LSVA 4TNVA 5SYOA 4TWHA 3U8KA 4FRRA 2BYQA 5J5HA 2Y7YA 4ZK4A 2BG9E 4NPPA 4UM3A 5HCMA 3EI0A 5AINA 5BRXA 2XQ8A 4ZZBA 1UX2A 3IGQA 3SQ9A 2BG9A 4TWFA 4XHEA
chains in the Genus database with same CATH superfamily
4ZRUA 3WTIA 5LG3A 4Z90A 5L47A 4ALXA 3SIOA 3SQ6A 3UU5A 3RHWA 2Y56A 5IUXA 5HCJA 2BR7A 2XYSA 3UQ4A 4ZZCA 2VL0A 2XQ4A 4COFA 3SH1A 4HFHA 5L4HA 3U8NA 3TLUA 2XNVA 2XZ6A 2BJ0A 1I9BA 3UU8A 3EAMA 4QH4A 3WTJA 3U8LA 3C84A 4UM3S 5HEHA 2BYRA 4ZK1A 2C9TA 2XYTA 2XZ5A 4IREA 4TNWA 4QH5A 5AFLA 2YKSA 5FJVA 2BYPA 4A98A 4TWDA 2W8FA 3UQ7A 5JMEA 2UZ6A 3TLWA 3UU4A 4BQTA 4IL4A 3P4WA 5AFKA 5J5GA 3UUBA 4IL9A 4ILCA 3WTKA 5LXBA 3JADA 5BP0A 5CO5A 3WTHA 4HFDA 4ZR6A 4AFHA 2XNUA 2QC1B 4LMLA 3GUAA 4AFTA 4B5DA 2YMEA 4HFEA 4PIRA 2BYSA 4UY2A 4HFBA 5AFNA 4DBMA 4ILBA 2Y58A 3PMZA 4QH1A 3WTOA 5KE4A 2Y57A 2YMDA 4HFCA 5TVCA 3C79A 3U8JA 3ZKRA 1UV6A 2WZYA 2PH9A 4ZJSA 5J5FA 5BW2A 4AFGA 3T4MA 4HFIA 4QABA 2X00D 2WNLA 2XQAA 3PEOA 5HEGA 3WIPA 2BG9C 4NZBA 3JAEA 4X5TA 3ZDHA 3U8MA 3JAFA 4BFQA 5AFMB 2Y54A 3RQWA 2WNJA 5CFBA 1UW6A 4LMJA 4ILAA 3WTMA 4UM3P 3UU3A 2YOEA 5J0ZA 2X00A 3RQUA 4QACA 5AFHA 4WV9A 3RIAA 4HQPA 4F8HA 2XQ6A 4XK9A 2BR8A 3EHZA 4D01A 3TLTA 5HEOA 3WTLA 3RI5A 3ZDGA 5AFMA 2XQ3A 5L4EA 4UM1A 3RIFA 4ZJTA 2XQ9A 2BYNA 2XQ7A 3TLSA 2W8GA 2XNTA 5J5IA 2WNCA 5HEUA 3P50A 4A97A 4Z91A 4QAAA 2YN6A 4LMKA 2WN9A 2BG9B 3TLVA 3UU6A 4UXUA 2ZJVA 3WTNA 5AFJA 2PGZA 2XQ5A 2ZJUA 4EZ1A 5KZUA 5HEJA 3LSVA 4TNVA 5SYOA 4TWHA 3U8KA 4FRRA 2BYQA 5J5HA 2Y7YA 4ZK4A 2BG9E 4NPPA 4UM3A 5HCMA 3EI0A 5AINA 5BRXA 2XQ8A 4ZZBA 1UX2A 3IGQA 3SQ9A 2BG9A 4TWFA 4XHEA
chains in the Genus database with same CATH topology
4ZRUA 3WTIA 5LG3A 4Z90A 5L47A 4ALXA 3SIOA 3SQ6A 3UU5A 3RHWA 2Y56A 5IUXA 5HCJA 2BR7A 2XYSA 3UQ4A 4ZZCA 2VL0A 2XQ4A 4COFA 3SH1A 4HFHA 5L4HA 3U8NA 3TLUA 2XNVA 2XZ6A 2BJ0A 1I9BA 3UU8A 3EAMA 4QH4A 3WTJA 3U8LA 3C84A 4UM3S 5HEHA 2BYRA 4ZK1A 2C9TA 2XYTA 2XZ5A 4IREA 4TNWA 4QH5A 5AFLA 2YKSA 5FJVA 2BYPA 4A98A 4TWDA 2W8FA 3UQ7A 5JMEA 2UZ6A 3TLWA 3UU4A 4BQTA 4IL4A 3P4WA 5AFKA 5J5GA 3UUBA 4IL9A 4ILCA 3WTKA 5LXBA 3JADA 5BP0A 5CO5A 3WTHA 4HFDA 4ZR6A 4AFHA 2XNUA 2QC1B 4LMLA 3GUAA 4AFTA 4B5DA 2YMEA 4HFEA 4PIRA 2BYSA 4UY2A 4HFBA 5AFNA 4DBMA 4ILBA 2Y58A 3PMZA 4QH1A 3WTOA 5KE4A 2Y57A 2YMDA 4HFCA 5TVCA 3C79A 3U8JA 3ZKRA 1UV6A 2WZYA 2PH9A 4ZJSA 5J5FA 5BW2A 4AFGA 3T4MA 4HFIA 4QABA 2X00D 2WNLA 2XQAA 3PEOA 5HEGA 3WIPA 2BG9C 4NZBA 3JAEA 4X5TA 3ZDHA 3U8MA 3JAFA 4BFQA 5AFMB 2Y54A 3RQWA 2WNJA 5CFBA 1UW6A 4LMJA 4ILAA 3WTMA 4UM3P 3UU3A 2YOEA 5J0ZA 2X00A 3RQUA 4QACA 5AFHA 4WV9A 3RIAA 4HQPA 4F8HA 2XQ6A 4XK9A 2BR8A 3EHZA 4D01A 3TLTA 5HEOA 3WTLA 3RI5A 3ZDGA 5AFMA 2XQ3A 5L4EA 4UM1A 3RIFA 4ZJTA 2XQ9A 2BYNA 2XQ7A 3TLSA 2W8GA 2XNTA 5J5IA 2WNCA 5HEUA 3P50A 4A97A 4Z91A 4QAAA 2YN6A 4LMKA 2WN9A 2BG9B 3TLVA 3UU6A 4UXUA 2ZJVA 3WTNA 5AFJA 2PGZA 2XQ5A 2ZJUA 4EZ1A 5KZUA 5HEJA 3LSVA 4TNVA 5SYOA 4TWHA 3U8KA 4FRRA 2BYQA 5J5HA 2Y7YA 4ZK4A 2BG9E 4NPPA 4UM3A 5HCMA 3EI0A 5AINA 5BRXA 2XQ8A 4ZZBA 1UX2A 3IGQA 3SQ9A 2BG9A 4TWFA 4XHEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZRU A;  3WTI A;  5LG3 A;  4Z90 A;  5L47 A;  4ALX A;  3SIO A;  3SQ6 A;  3UU5 A;  3RHW A;  2Y56 A;  5IUX A;  5HCJ A;  2BR7 A;  2XYS A;  3UQ4 A;  4ZZC A;  2VL0 A;  2XQ4 A;  4COF A;  3SH1 A;  4HFH A;  5L4H A;  3U8N A;  3TLU A;  2XNV A;  2XZ6 A;  2BJ0 A;  1I9B A;  3UU8 A;  3EAM A;  4QH4 A;  3WTJ A;  3U8L A;  3C84 A;  4UM3 S;  5HEH A;  2BYR A;  4ZK1 A;  2C9T A;  2XYT A;  2XZ5 A;  4IRE A;  4TNW A;  4QH5 A;  5AFL A;  2YKS A;  5FJV A;  2BYP A;  4A98 A;  4TWD A;  2W8F A;  3UQ7 A;  5JME A;  2UZ6 A;  3TLW A;  3UU4 A;  4BQT A;  4IL4 A;  3P4W A;  5AFK A;  5J5G A;  3UUB A;  4IL9 A;  4ILC A;  3WTK A;  5LXB A;  3JAD A;  5BP0 A;  5CO5 A;  3WTH A;  4HFD A;  4ZR6 A;  4AFH A;  2XNU A;  2QC1 B;  4LML A;  3GUA A;  4AFT A;  4B5D A;  2YME A;  4HFE A;  4PIR A;  2BYS A;  4UY2 A;  4HFB A;  5AFN A;  4DBM A;  4ILB A;  2Y58 A;  3PMZ A;  4QH1 A;  3WTO A;  5KE4 A;  2Y57 A;  2YMD A;  4HFC A;  5TVC A;  3C79 A;  3U8J A;  3ZKR A;  1UV6 A;  2WZY A;  2PH9 A;  4ZJS A;  5J5F A;  5BW2 A;  4AFG A;  3T4M A;  4HFI A;  4QAB A;  2X00 D;  2WNL A;  2XQA A;  3PEO A;  5HEG A;  3WIP A;  2BG9 C;  4NZB A;  3JAE A;  4X5T A;  3ZDH A;  3U8M A;  3JAF A;  4BFQ A;  5AFM B;  2Y54 A;  3RQW A;  2WNJ A;  5CFB A;  1UW6 A;  4LMJ A;  4ILA A;  3WTM A;  4UM3 P;  3UU3 A;  2YOE A;  5J0Z A;  2X00 A;  3RQU A;  4QAC A;  5AFH A;  4WV9 A;  3RIA A;  4HQP A;  4F8H A;  2XQ6 A;  4XK9 A;  2BR8 A;  3EHZ A;  4D01 A;  3TLT A;  5HEO A;  3WTL A;  3RI5 A;  3ZDG A;  5AFM A;  2XQ3 A;  5L4E A;  4UM1 A;  3RIF A;  4ZJT A;  2XQ9 A;  2BYN A;  2XQ7 A;  3TLS A;  2W8G A;  2XNT A;  5J5I A;  2WNC A;  5HEU A;  3P50 A;  4A97 A;  4Z91 A;  4QAA A;  2YN6 A;  4LMK A;  2WN9 A;  2BG9 B;  3TLV A;  3UU6 A;  4UXU A;  2ZJV A;  3WTN A;  5AFJ A;  2PGZ A;  2XQ5 A;  2ZJU A;  4EZ1 A;  5KZU A;  5HEJ A;  3LSV A;  4TNV A;  5SYO A;  4TWH A;  3U8K A;  4FRR A;  2BYQ A;  5J5H A;  2Y7Y A;  4ZK4 A;  2BG9 E;  4NPP A;  4UM3 A;  5HCM A;  3EI0 A;  5AIN A;  5BRX A;  2XQ8 A;  4ZZB A;  1UX2 A;  3IGQ A;  3SQ9 A;  2BG9 A;  4TWF A;  4XHE A; 
#chains in the Genus database with same CATH topology
 4ZRU A;  3WTI A;  5LG3 A;  4Z90 A;  5L47 A;  4ALX A;  3SIO A;  3SQ6 A;  3UU5 A;  3RHW A;  2Y56 A;  5IUX A;  5HCJ A;  2BR7 A;  2XYS A;  3UQ4 A;  4ZZC A;  2VL0 A;  2XQ4 A;  4COF A;  3SH1 A;  4HFH A;  5L4H A;  3U8N A;  3TLU A;  2XNV A;  2XZ6 A;  2BJ0 A;  1I9B A;  3UU8 A;  3EAM A;  4QH4 A;  3WTJ A;  3U8L A;  3C84 A;  4UM3 S;  5HEH A;  2BYR A;  4ZK1 A;  2C9T A;  2XYT A;  2XZ5 A;  4IRE A;  4TNW A;  4QH5 A;  5AFL A;  2YKS A;  5FJV A;  2BYP A;  4A98 A;  4TWD A;  2W8F A;  3UQ7 A;  5JME A;  2UZ6 A;  3TLW A;  3UU4 A;  4BQT A;  4IL4 A;  3P4W A;  5AFK A;  5J5G A;  3UUB A;  4IL9 A;  4ILC A;  3WTK A;  5LXB A;  3JAD A;  5BP0 A;  5CO5 A;  3WTH A;  4HFD A;  4ZR6 A;  4AFH A;  2XNU A;  2QC1 B;  4LML A;  3GUA A;  4AFT A;  4B5D A;  2YME A;  4HFE A;  4PIR A;  2BYS A;  4UY2 A;  4HFB A;  5AFN A;  4DBM A;  4ILB A;  2Y58 A;  3PMZ A;  4QH1 A;  3WTO A;  5KE4 A;  2Y57 A;  2YMD A;  4HFC A;  5TVC A;  3C79 A;  3U8J A;  3ZKR A;  1UV6 A;  2WZY A;  2PH9 A;  4ZJS A;  5J5F A;  5BW2 A;  4AFG A;  3T4M A;  4HFI A;  4QAB A;  2X00 D;  2WNL A;  2XQA A;  3PEO A;  5HEG A;  3WIP A;  2BG9 C;  4NZB A;  3JAE A;  4X5T A;  3ZDH A;  3U8M A;  3JAF A;  4BFQ A;  5AFM B;  2Y54 A;  3RQW A;  2WNJ A;  5CFB A;  1UW6 A;  4LMJ A;  4ILA A;  3WTM A;  4UM3 P;  3UU3 A;  2YOE A;  5J0Z A;  2X00 A;  3RQU A;  4QAC A;  5AFH A;  4WV9 A;  3RIA A;  4HQP A;  4F8H A;  2XQ6 A;  4XK9 A;  2BR8 A;  3EHZ A;  4D01 A;  3TLT A;  5HEO A;  3WTL A;  3RI5 A;  3ZDG A;  5AFM A;  2XQ3 A;  5L4E A;  4UM1 A;  3RIF A;  4ZJT A;  2XQ9 A;  2BYN A;  2XQ7 A;  3TLS A;  2W8G A;  2XNT A;  5J5I A;  2WNC A;  5HEU A;  3P50 A;  4A97 A;  4Z91 A;  4QAA A;  2YN6 A;  4LMK A;  2WN9 A;  2BG9 B;  3TLV A;  3UU6 A;  4UXU A;  2ZJV A;  3WTN A;  5AFJ A;  2PGZ A;  2XQ5 A;  2ZJU A;  4EZ1 A;  5KZU A;  5HEJ A;  3LSV A;  4TNV A;  5SYO A;  4TWH A;  3U8K A;  4FRR A;  2BYQ A;  5J5H A;  2Y7Y A;  4ZK4 A;  2BG9 E;  4NPP A;  4UM3 A;  5HCM A;  3EI0 A;  5AIN A;  5BRX A;  2XQ8 A;  4ZZB A;  1UX2 A;  3IGQ A;  3SQ9 A;  2BG9 A;  4TWF A;  4XHE A; 
#chains in the Genus database with same CATH homology
 4ZRU A;  3WTI A;  5LG3 A;  4Z90 A;  5L47 A;  4ALX A;  3SIO A;  3SQ6 A;  3UU5 A;  3RHW A;  2Y56 A;  5IUX A;  5HCJ A;  2BR7 A;  2XYS A;  3UQ4 A;  4ZZC A;  2VL0 A;  2XQ4 A;  4COF A;  3SH1 A;  4HFH A;  5L4H A;  3U8N A;  3TLU A;  2XNV A;  2XZ6 A;  2BJ0 A;  1I9B A;  3UU8 A;  3EAM A;  4QH4 A;  3WTJ A;  3U8L A;  3C84 A;  4UM3 S;  5HEH A;  2BYR A;  4ZK1 A;  2C9T A;  2XYT A;  2XZ5 A;  4IRE A;  4TNW A;  4QH5 A;  5AFL A;  2YKS A;  5FJV A;  2BYP A;  4A98 A;  4TWD A;  2W8F A;  3UQ7 A;  5JME A;  2UZ6 A;  3TLW A;  3UU4 A;  4BQT A;  4IL4 A;  3P4W A;  5AFK A;  5J5G A;  3UUB A;  4IL9 A;  4ILC A;  3WTK A;  5LXB A;  3JAD A;  5BP0 A;  5CO5 A;  3WTH A;  4HFD A;  4ZR6 A;  4AFH A;  2XNU A;  2QC1 B;  4LML A;  3GUA A;  4AFT A;  4B5D A;  2YME A;  4HFE A;  4PIR A;  2BYS A;  4UY2 A;  4HFB A;  5AFN A;  4DBM A;  4ILB A;  2Y58 A;  3PMZ A;  4QH1 A;  3WTO A;  5KE4 A;  2Y57 A;  2YMD A;  4HFC A;  5TVC A;  3C79 A;  3U8J A;  3ZKR A;  1UV6 A;  2WZY A;  2PH9 A;  4ZJS A;  5J5F A;  5BW2 A;  4AFG A;  3T4M A;  4HFI A;  4QAB A;  2X00 D;  2WNL A;  2XQA A;  3PEO A;  5HEG A;  3WIP A;  2BG9 C;  4NZB A;  3JAE A;  4X5T A;  3ZDH A;  3U8M A;  3JAF A;  4BFQ A;  5AFM B;  2Y54 A;  3RQW A;  2WNJ A;  5CFB A;  1UW6 A;  4LMJ A;  4ILA A;  3WTM A;  4UM3 P;  3UU3 A;  2YOE A;  5J0Z A;  2X00 A;  3RQU A;  4QAC A;  5AFH A;  4WV9 A;  3RIA A;  4HQP A;  4F8H A;  2XQ6 A;  4XK9 A;  2BR8 A;  3EHZ A;  4D01 A;  3TLT A;  5HEO A;  3WTL A;  3RI5 A;  3ZDG A;  5AFM A;  2XQ3 A;  5L4E A;  4UM1 A;  3RIF A;  4ZJT A;  2XQ9 A;  2BYN A;  2XQ7 A;  3TLS A;  2W8G A;  2XNT A;  5J5I A;  2WNC A;  5HEU A;  3P50 A;  4A97 A;  4Z91 A;  4QAA A;  2YN6 A;  4LMK A;  2WN9 A;  2BG9 B;  3TLV A;  3UU6 A;  4UXU A;  2ZJV A;  3WTN A;  5AFJ A;  2PGZ A;  2XQ5 A;  2ZJU A;  4EZ1 A;  5KZU A;  5HEJ A;  3LSV A;  4TNV A;  5SYO A;  4TWH A;  3U8K A;  4FRR A;  2BYQ A;  5J5H A;  2Y7Y A;  4ZK4 A;  2BG9 E;  4NPP A;  4UM3 A;  5HCM A;  3EI0 A;  5AIN A;  5BRX A;  2XQ8 A;  4ZZB A;  1UX2 A;  3IGQ A;  3SQ9 A;  2BG9 A;  4TWF A;  4XHE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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