3T4M | Genus

Total Genus 49

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	49
sequence length	214
structure length	214
Chain Sequence	KDDDDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYWEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQNALVTHDGSVQYLPAQRLSFMCDPTGVDSEEGATCAVKFGSWSYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVRFYECCKEPYPDVNLVVKFRER

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Receptor
source organism	Aplysia californica
publication title	Creating an alpha-7 nicotinic acetylcholine recognition domain from the acetylcholine binding protein: crystallographic and ligand selectivity analyses pubmed doi rcsb
molecule keywords	Soluble acetylcholine receptor
total genus	49
structure length	214
sequence length	214
chains with identical sequence	B, C, D, E, F, G, H, I, J
ec nomenclature
pdb deposition date	2011-07-26

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF02931	Neur_chan_LBD	Neurotransmitter-gated ion-channel ligand binding domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.70.170.10	Mainly Beta	Distorted Sandwich	Acetylcholine Binding Protein; Chain: A,	Neurotransmitter-gated ion-channel ligand-binding domain	3t4mA00

5L4EA 2XQ6A 2YOEA 4ZK1A 4A97A 5J5HA 4UM3P 2BYRA 4ZJSA 4HFHA 4ZR6A 5AFHA 5L4HA 4QH4A 5TVCA 3TLTA 3WIPA 2XNTA 4BFQA 4PIRA 4QAAA 3TLUA 3WTOA 3WTIA 4ZZBA 3RQUA 2YN6A 3P50A 4AFTA 2BG9E 5AFNA 4TWFA 4D01A 4UY2A 2BR8A 2XZ6A 3RHWA 5L47A 4TWHA 5BP0A 1I9BA 5SYOA 5LXBA 2Y54A 4ILCA 2ZJUA 3JAEA 1UV6A 2QC1B 3UUBA 5J5GA 3WTHA 4X5TA 5AFJA 4FRRA 4QH5A 4XHEA 5HEHA 2BR7A 5FJVA 5AINA 5CFBA 2UZ6A 3JADA 2X00D 2X00A 2XZ5A 4XK9A 5LG3A 2WZYA 4QACA 3TLWA 5HCJA 2W8FA 4B5DA 2WNJA 2BJ0A 3U8LA 2W8GA 3U8NA 4HQPA 4IL9A 2PGZA 4UM3S 4WV9A 4ZJTA 4NZBA 4TNWA 2Y56A 4UM1A 3UU4A 4UM3A 3TLVA 3U8JA 3ZKRA 5JMEA 3UU8A 2BYNA 4HFIA 2XQ3A 2Y57A 3EAMA 4ZRUA 2XQ9A 2YKSA 4BQTA 3EHZA 2Y58A 4COFA 2C9TA 3SQ9A 4DBMA 2XYTA 5HEGA 3RIAA 5KE4A 4ILBA 3UU5A 3UQ7A 2YMEA 3RIFA 3SH1A 4A98A 4ZZCA 3SIOA 3RQWA 4Z90A 5KZUA 3GUAA 4UXUA 5AFMB 5J5IA 5J5FA 2BG9B 5BRXA 2BYQA 3EI0A 2BYSA 3PEOA 4LMKA 4TWDA 3U8KA 4HFEA 4Z91A 5AFLA 1UX2A 2XQ8A 3WTMA 2XQ4A 3SQ6A 2WNLA 5J0ZA 2ZJVA 3WTLA 2VL0A 5CO5A 4AFHA 5BW2A 3JAFA 5HCMA 3ZDHA 4IL4A 4AFGA 4QABA 1UW6A 3TLSA 4IREA 5AFKA 3RI5A 2BG9C 3IGQA 3P4WA 4NPPA 4F8HA 4ZK4A 4ALXA 5IUXA 2WN9A 4QH1A 3UU3A 3WTKA 4HFBA 3WTJA 2YMDA 5HEUA 3ZDGA 3PMZA 2Y7YA 3C84A 4HFDA 3UQ4A 2XNVA 2XQ7A 3LSVA 3WTNA 4LMLA 4HFCA 3T4MA 4TNVA 3UU6A 2XNUA 2XQ5A 2XQAA 4LMJA 5AFMA 5HEJA 4ILAA 4EZ1A 2BG9A 2PH9A 3C79A 5HEOA 2BYPA 2XYSA 3U8MA 2WNCA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 5L4E A;  2XQ6 A;  2YOE A;  4ZK1 A;  4A97 A;  5J5H A;  4UM3 P;  2BYR A;  4ZJS A;  4HFH A;  4ZR6 A;  5AFH A;  5L4H A;  4QH4 A;  5TVC A;  3TLT A;  3WIP A;  2XNT A;  4BFQ A;  4PIR A;  4QAA A;  3TLU A;  3WTO A;  3WTI A;  4ZZB A;  3RQU A;  2YN6 A;  3P50 A;  4AFT A;  2BG9 E;  5AFN A;  4TWF A;  4D01 A;  4UY2 A;  2BR8 A;  2XZ6 A;  3RHW A;  5L47 A;  4TWH A;  5BP0 A;  1I9B A;  5SYO A;  5LXB A;  2Y54 A;  4ILC A;  2ZJU A;  3JAE A;  1UV6 A;  2QC1 B;  3UUB A;  5J5G A;  3WTH A;  4X5T A;  5AFJ A;  4FRR A;  4QH5 A;  4XHE A;  5HEH A;  2BR7 A;  5FJV A;  5AIN A;  5CFB A;  2UZ6 A;  3JAD A;  2X00 D;  2X00 A;  2XZ5 A;  4XK9 A;  5LG3 A;  2WZY A;  4QAC A;  3TLW A;  5HCJ A;  2W8F A;  4B5D A;  2WNJ A;  2BJ0 A;  3U8L A;  2W8G A;  3U8N A;  4HQP A;  4IL9 A;  2PGZ A;  4UM3 S;  4WV9 A;  4ZJT A;  4NZB A;  4TNW A;  2Y56 A;  4UM1 A;  3UU4 A;  4UM3 A;  3TLV A;  3U8J A;  3ZKR A;  5JME A;  3UU8 A;  2BYN A;  4HFI A;  2XQ3 A;  2Y57 A;  3EAM A;  4ZRU A;  2XQ9 A;  2YKS A;  4BQT A;  3EHZ A;  2Y58 A;  4COF A;  2C9T A;  3SQ9 A;  4DBM A;  2XYT A;  5HEG A;  3RIA A;  5KE4 A;  4ILB A;  3UU5 A;  3UQ7 A;  2YME A;  3RIF A;  3SH1 A;  4A98 A;  4ZZC A;  3SIO A;  3RQW A;  4Z90 A;  5KZU A;  3GUA A;  4UXU A;  5AFM B;  5J5I A;  5J5F A;  2BG9 B;  5BRX A;  2BYQ A;  3EI0 A;  2BYS A;  3PEO A;  4LMK A;  4TWD A;  3U8K A;  4HFE A;  4Z91 A;  5AFL A;  1UX2 A;  2XQ8 A;  3WTM A;  2XQ4 A;  3SQ6 A;  2WNL A;  5J0Z A;  2ZJV A;  3WTL A;  2VL0 A;  5CO5 A;  4AFH A;  5BW2 A;  3JAF A;  5HCM A;  3ZDH A;  4IL4 A;  4AFG A;  4QAB A;  1UW6 A;  3TLS A;  4IRE A;  5AFK A;  3RI5 A;  2BG9 C;  3IGQ A;  3P4W A;  4NPP A;  4F8H A;  4ZK4 A;  4ALX A;  5IUX A;  2WN9 A;  4QH1 A;  3UU3 A;  3WTK A;  4HFB A;  3WTJ A;  2YMD A;  5HEU A;  3ZDG A;  3PMZ A;  2Y7Y A;  3C84 A;  4HFD A;  3UQ4 A;  2XNV A;  2XQ7 A;  3LSV A;  3WTN A;  4LML A;  4HFC A;  3T4M A;  4TNV A;  3UU6 A;  2XNU A;  2XQ5 A;  2XQA A;  4LMJ A;  5AFM A;  5HEJ A;  4ILA A;  4EZ1 A;  2BG9 A;  2PH9 A;  3C79 A;  5HEO A;  2BYP A;  2XYS A;  3U8M A;  2WNC A; 
#chains in the Genus database with same CATH topology
 5L4E A;  2XQ6 A;  2YOE A;  4ZK1 A;  4A97 A;  5J5H A;  4UM3 P;  2BYR A;  4ZJS A;  4HFH A;  4ZR6 A;  5AFH A;  5L4H A;  4QH4 A;  5TVC A;  3TLT A;  3WIP A;  2XNT A;  4BFQ A;  4PIR A;  4QAA A;  3TLU A;  3WTO A;  3WTI A;  4ZZB A;  3RQU A;  2YN6 A;  3P50 A;  4AFT A;  2BG9 E;  5AFN A;  4TWF A;  4D01 A;  4UY2 A;  2BR8 A;  2XZ6 A;  3RHW A;  5L47 A;  4TWH A;  5BP0 A;  1I9B A;  5SYO A;  5LXB A;  2Y54 A;  4ILC A;  2ZJU A;  3JAE A;  1UV6 A;  2QC1 B;  3UUB A;  5J5G A;  3WTH A;  4X5T A;  5AFJ A;  4FRR A;  4QH5 A;  4XHE A;  5HEH A;  2BR7 A;  5FJV A;  5AIN A;  5CFB A;  2UZ6 A;  3JAD A;  2X00 D;  2X00 A;  2XZ5 A;  4XK9 A;  5LG3 A;  2WZY A;  4QAC A;  3TLW A;  5HCJ A;  2W8F A;  4B5D A;  2WNJ A;  2BJ0 A;  3U8L A;  2W8G A;  3U8N A;  4HQP A;  4IL9 A;  2PGZ A;  4UM3 S;  4WV9 A;  4ZJT A;  4NZB A;  4TNW A;  2Y56 A;  4UM1 A;  3UU4 A;  4UM3 A;  3TLV A;  3U8J A;  3ZKR A;  5JME A;  3UU8 A;  2BYN A;  4HFI A;  2XQ3 A;  2Y57 A;  3EAM A;  4ZRU A;  2XQ9 A;  2YKS A;  4BQT A;  3EHZ A;  2Y58 A;  4COF A;  2C9T A;  3SQ9 A;  4DBM A;  2XYT A;  5HEG A;  3RIA A;  5KE4 A;  4ILB A;  3UU5 A;  3UQ7 A;  2YME A;  3RIF A;  3SH1 A;  4A98 A;  4ZZC A;  3SIO A;  3RQW A;  4Z90 A;  5KZU A;  3GUA A;  4UXU A;  5AFM B;  5J5I A;  5J5F A;  2BG9 B;  5BRX A;  2BYQ A;  3EI0 A;  2BYS A;  3PEO A;  4LMK A;  4TWD A;  3U8K A;  4HFE A;  4Z91 A;  5AFL A;  1UX2 A;  2XQ8 A;  3WTM A;  2XQ4 A;  3SQ6 A;  2WNL A;  5J0Z A;  2ZJV A;  3WTL A;  2VL0 A;  5CO5 A;  4AFH A;  5BW2 A;  3JAF A;  5HCM A;  3ZDH A;  4IL4 A;  4AFG A;  4QAB A;  1UW6 A;  3TLS A;  4IRE A;  5AFK A;  3RI5 A;  2BG9 C;  3IGQ A;  3P4W A;  4NPP A;  4F8H A;  4ZK4 A;  4ALX A;  5IUX A;  2WN9 A;  4QH1 A;  3UU3 A;  3WTK A;  4HFB A;  3WTJ A;  2YMD A;  5HEU A;  3ZDG A;  3PMZ A;  2Y7Y A;  3C84 A;  4HFD A;  3UQ4 A;  2XNV A;  2XQ7 A;  3LSV A;  3WTN A;  4LML A;  4HFC A;  3T4M A;  4TNV A;  3UU6 A;  2XNU A;  2XQ5 A;  2XQA A;  4LMJ A;  5AFM A;  5HEJ A;  4ILA A;  4EZ1 A;  2BG9 A;  2PH9 A;  3C79 A;  5HEO A;  2BYP A;  2XYS A;  3U8M A;  2WNC A; 
#chains in the Genus database with same CATH homology
 5L4E A;  2XQ6 A;  2YOE A;  4ZK1 A;  4A97 A;  5J5H A;  4UM3 P;  2BYR A;  4ZJS A;  4HFH A;  4ZR6 A;  5AFH A;  5L4H A;  4QH4 A;  5TVC A;  3TLT A;  3WIP A;  2XNT A;  4BFQ A;  4PIR A;  4QAA A;  3TLU A;  3WTO A;  3WTI A;  4ZZB A;  3RQU A;  2YN6 A;  3P50 A;  4AFT A;  2BG9 E;  5AFN A;  4TWF A;  4D01 A;  4UY2 A;  2BR8 A;  2XZ6 A;  3RHW A;  5L47 A;  4TWH A;  5BP0 A;  1I9B A;  5SYO A;  5LXB A;  2Y54 A;  4ILC A;  2ZJU A;  3JAE A;  1UV6 A;  2QC1 B;  3UUB A;  5J5G A;  3WTH A;  4X5T A;  5AFJ A;  4FRR A;  4QH5 A;  4XHE A;  5HEH A;  2BR7 A;  5FJV A;  5AIN A;  5CFB A;  2UZ6 A;  3JAD A;  2X00 D;  2X00 A;  2XZ5 A;  4XK9 A;  5LG3 A;  2WZY A;  4QAC A;  3TLW A;  5HCJ A;  2W8F A;  4B5D A;  2WNJ A;  2BJ0 A;  3U8L A;  2W8G A;  3U8N A;  4HQP A;  4IL9 A;  2PGZ A;  4UM3 S;  4WV9 A;  4ZJT A;  4NZB A;  4TNW A;  2Y56 A;  4UM1 A;  3UU4 A;  4UM3 A;  3TLV A;  3U8J A;  3ZKR A;  5JME A;  3UU8 A;  2BYN A;  4HFI A;  2XQ3 A;  2Y57 A;  3EAM A;  4ZRU A;  2XQ9 A;  2YKS A;  4BQT A;  3EHZ A;  2Y58 A;  4COF A;  2C9T A;  3SQ9 A;  4DBM A;  2XYT A;  5HEG A;  3RIA A;  5KE4 A;  4ILB A;  3UU5 A;  3UQ7 A;  2YME A;  3RIF A;  3SH1 A;  4A98 A;  4ZZC A;  3SIO A;  3RQW A;  4Z90 A;  5KZU A;  3GUA A;  4UXU A;  5AFM B;  5J5I A;  5J5F A;  2BG9 B;  5BRX A;  2BYQ A;  3EI0 A;  2BYS A;  3PEO A;  4LMK A;  4TWD A;  3U8K A;  4HFE A;  4Z91 A;  5AFL A;  1UX2 A;  2XQ8 A;  3WTM A;  2XQ4 A;  3SQ6 A;  2WNL A;  5J0Z A;  2ZJV A;  3WTL A;  2VL0 A;  5CO5 A;  4AFH A;  5BW2 A;  3JAF A;  5HCM A;  3ZDH A;  4IL4 A;  4AFG A;  4QAB A;  1UW6 A;  3TLS A;  4IRE A;  5AFK A;  3RI5 A;  2BG9 C;  3IGQ A;  3P4W A;  4NPP A;  4F8H A;  4ZK4 A;  4ALX A;  5IUX A;  2WN9 A;  4QH1 A;  3UU3 A;  3WTK A;  4HFB A;  3WTJ A;  2YMD A;  5HEU A;  3ZDG A;  3PMZ A;  2Y7Y A;  3C84 A;  4HFD A;  3UQ4 A;  2XNV A;  2XQ7 A;  3LSV A;  3WTN A;  4LML A;  4HFC A;  3T4M A;  4TNV A;  3UU6 A;  2XNU A;  2XQ5 A;  2XQA A;  4LMJ A;  5AFM A;  5HEJ A;  4ILA A;  4EZ1 A;  2BG9 A;  2PH9 A;  3C79 A;  5HEO A;  2BYP A;  2XYS A;  3U8M A;  2WNC A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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3T4MA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations