3WIP | Genus

Total Genus 47

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	47
sequence length	205
structure length	202
Chain Sequence	LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Acetylcholine-binding protein
source organism	Lymnaea stagnalis
publication title	Molecular recognition of the neurotransmitter acetylcholine by an acetylcholine binding protein reveals determinants of binding to nicotinic acetylcholine receptors pubmed doi rcsb
molecule keywords	Acetylcholine-binding protein
total genus	47
structure length	202
sequence length	205
chains with identical sequence	B, C, D, E, F, G, H, I, J
ec nomenclature
pdb deposition date	2013-09-24

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF02931	Neur_chan_LBD	Neurotransmitter-gated ion-channel ligand binding domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.70.170.10	Mainly Beta	Distorted Sandwich	Acetylcholine Binding Protein; Chain: A,	Neurotransmitter-gated ion-channel ligand-binding domain	3wipA00

3ZDHA 4HFDA 3EHZA 5TVCA 2XYSA 3JAEA 4TNWA 2BYRA 4QAAA 3TLSA 5AFMA 2WNJA 3P50A 4UY2A 3RHWA 5HEJA 5AFJA 5IUXA 3GUAA 3EAMA 2XQ3A 2XZ6A 4HFCA 2XNVA 3P4WA 5L4EA 4ILBA 5HEHA 4HFEA 2WNLA 2BR7A 1UV6A 2BG9C 3IGQA 2WNCA 3WTKA 4COFA 4PIRA 3UU3A 4UM1A 1I9BA 3C79A 3RQWA 3WTHA 4QH4A 3U8NA 2XYTA 4XK9A 3TLUA 4UXUA 4UM3P 5BRXA 5KE4A 5HEOA 2YN6A 2XQ9A 2XNUA 2W8GA 2BR8A 2BG9B 2BYNA 3PEOA 4LMJA 5HEGA 2ZJVA 3WTNA 2C9TA 5AFHA 4F8HA 5J5IA 3SQ6A 3RIAA 2XQ4A 4NPPA 4QACA 3SH1A 2YMDA 2Y56A 5JMEA 3WTMA 2BG9E 3UU4A 3WTOA 3U8LA 4HQPA 3RIFA 4AFGA 3T4MA 3UU6A 5LG3A 3TLVA 4WV9A 3SIOA 3SQ9A 2PH9A 4UM3S 1UX2A 4B5DA 3UUBA 3ZDGA 5BP0A 5FJVA 5J0ZA 4A98A 4BQTA 3TLWA 2XNTA 4X5TA 2YKSA 5AFMB 2BYQA 4FRRA 4NZBA 4Z91A 3U8KA 5L47A 3UQ4A 4TWDA 3U8JA 2BYSA 5HCMA 4ZJTA 5AFLA 4ZJSA 4Z90A 2W8FA 2X00D 5AINA 2VL0A 4ZK1A 3RI5A 5J5HA 4ILCA 3EI0A 4TWFA 2QC1B 4HFHA 2XQ6A 2YOEA 4LMLA 5J5GA 4ZZCA 5BW2A 4TWHA 4D01A 4IL9A 4ZR6A 2XQAA 3C84A 4QH1A 4HFBA 4LMKA 2XQ5A 5HEUA 4A97A 2XQ7A 4QABA 5SYOA 4ZRUA 4IL4A 5HCJA 3RQUA 4DBMA 3UU5A 4QH5A 4AFHA 5J5FA 3JAFA 3U8MA 5L4HA 2Y58A 3TLTA 4BFQA 4ILAA 4AFTA 4HFIA 3PMZA 3JADA 3UU8A 3ZKRA 4ZZBA 2PGZA 5CFBA 2BG9A 2BYPA 5CO5A 4ALXA 4TNVA 5KZUA 4EZ1A 3WTJA 2X00A 4XHEA 3WIPA 3WTIA 5LXBA 2BJ0A 2UZ6A 2Y7YA 2XQ8A 3LSVA 4ZK4A 4IREA 5AFKA 2WZYA 3UQ7A 4UM3A 1UW6A 2YMEA 2XZ5A 2ZJUA 2Y57A 2WN9A 2Y54A 5AFNA 3WTLA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 3ZDH A;  4HFD A;  3EHZ A;  5TVC A;  2XYS A;  3JAE A;  4TNW A;  2BYR A;  4QAA A;  3TLS A;  5AFM A;  2WNJ A;  3P50 A;  4UY2 A;  3RHW A;  5HEJ A;  5AFJ A;  5IUX A;  3GUA A;  3EAM A;  2XQ3 A;  2XZ6 A;  4HFC A;  2XNV A;  3P4W A;  5L4E A;  4ILB A;  5HEH A;  4HFE A;  2WNL A;  2BR7 A;  1UV6 A;  2BG9 C;  3IGQ A;  2WNC A;  3WTK A;  4COF A;  4PIR A;  3UU3 A;  4UM1 A;  1I9B A;  3C79 A;  3RQW A;  3WTH A;  4QH4 A;  3U8N A;  2XYT A;  4XK9 A;  3TLU A;  4UXU A;  4UM3 P;  5BRX A;  5KE4 A;  5HEO A;  2YN6 A;  2XQ9 A;  2XNU A;  2W8G A;  2BR8 A;  2BG9 B;  2BYN A;  3PEO A;  4LMJ A;  5HEG A;  2ZJV A;  3WTN A;  2C9T A;  5AFH A;  4F8H A;  5J5I A;  3SQ6 A;  3RIA A;  2XQ4 A;  4NPP A;  4QAC A;  3SH1 A;  2YMD A;  2Y56 A;  5JME A;  3WTM A;  2BG9 E;  3UU4 A;  3WTO A;  3U8L A;  4HQP A;  3RIF A;  4AFG A;  3T4M A;  3UU6 A;  5LG3 A;  3TLV A;  4WV9 A;  3SIO A;  3SQ9 A;  2PH9 A;  4UM3 S;  1UX2 A;  4B5D A;  3UUB A;  3ZDG A;  5BP0 A;  5FJV A;  5J0Z A;  4A98 A;  4BQT A;  3TLW A;  2XNT A;  4X5T A;  2YKS A;  5AFM B;  2BYQ A;  4FRR A;  4NZB A;  4Z91 A;  3U8K A;  5L47 A;  3UQ4 A;  4TWD A;  3U8J A;  2BYS A;  5HCM A;  4ZJT A;  5AFL A;  4ZJS A;  4Z90 A;  2W8F A;  2X00 D;  5AIN A;  2VL0 A;  4ZK1 A;  3RI5 A;  5J5H A;  4ILC A;  3EI0 A;  4TWF A;  2QC1 B;  4HFH A;  2XQ6 A;  2YOE A;  4LML A;  5J5G A;  4ZZC A;  5BW2 A;  4TWH A;  4D01 A;  4IL9 A;  4ZR6 A;  2XQA A;  3C84 A;  4QH1 A;  4HFB A;  4LMK A;  2XQ5 A;  5HEU A;  4A97 A;  2XQ7 A;  4QAB A;  5SYO A;  4ZRU A;  4IL4 A;  5HCJ A;  3RQU A;  4DBM A;  3UU5 A;  4QH5 A;  4AFH A;  5J5F A;  3JAF A;  3U8M A;  5L4H A;  2Y58 A;  3TLT A;  4BFQ A;  4ILA A;  4AFT A;  4HFI A;  3PMZ A;  3JAD A;  3UU8 A;  3ZKR A;  4ZZB A;  2PGZ A;  5CFB A;  2BG9 A;  2BYP A;  5CO5 A;  4ALX A;  4TNV A;  5KZU A;  4EZ1 A;  3WTJ A;  2X00 A;  4XHE A;  3WIP A;  3WTI A;  5LXB A;  2BJ0 A;  2UZ6 A;  2Y7Y A;  2XQ8 A;  3LSV A;  4ZK4 A;  4IRE A;  5AFK A;  2WZY A;  3UQ7 A;  4UM3 A;  1UW6 A;  2YME A;  2XZ5 A;  2ZJU A;  2Y57 A;  2WN9 A;  2Y54 A;  5AFN A;  3WTL A; 
#chains in the Genus database with same CATH topology
 3ZDH A;  4HFD A;  3EHZ A;  5TVC A;  2XYS A;  3JAE A;  4TNW A;  2BYR A;  4QAA A;  3TLS A;  5AFM A;  2WNJ A;  3P50 A;  4UY2 A;  3RHW A;  5HEJ A;  5AFJ A;  5IUX A;  3GUA A;  3EAM A;  2XQ3 A;  2XZ6 A;  4HFC A;  2XNV A;  3P4W A;  5L4E A;  4ILB A;  5HEH A;  4HFE A;  2WNL A;  2BR7 A;  1UV6 A;  2BG9 C;  3IGQ A;  2WNC A;  3WTK A;  4COF A;  4PIR A;  3UU3 A;  4UM1 A;  1I9B A;  3C79 A;  3RQW A;  3WTH A;  4QH4 A;  3U8N A;  2XYT A;  4XK9 A;  3TLU A;  4UXU A;  4UM3 P;  5BRX A;  5KE4 A;  5HEO A;  2YN6 A;  2XQ9 A;  2XNU A;  2W8G A;  2BR8 A;  2BG9 B;  2BYN A;  3PEO A;  4LMJ A;  5HEG A;  2ZJV A;  3WTN A;  2C9T A;  5AFH A;  4F8H A;  5J5I A;  3SQ6 A;  3RIA A;  2XQ4 A;  4NPP A;  4QAC A;  3SH1 A;  2YMD A;  2Y56 A;  5JME A;  3WTM A;  2BG9 E;  3UU4 A;  3WTO A;  3U8L A;  4HQP A;  3RIF A;  4AFG A;  3T4M A;  3UU6 A;  5LG3 A;  3TLV A;  4WV9 A;  3SIO A;  3SQ9 A;  2PH9 A;  4UM3 S;  1UX2 A;  4B5D A;  3UUB A;  3ZDG A;  5BP0 A;  5FJV A;  5J0Z A;  4A98 A;  4BQT A;  3TLW A;  2XNT A;  4X5T A;  2YKS A;  5AFM B;  2BYQ A;  4FRR A;  4NZB A;  4Z91 A;  3U8K A;  5L47 A;  3UQ4 A;  4TWD A;  3U8J A;  2BYS A;  5HCM A;  4ZJT A;  5AFL A;  4ZJS A;  4Z90 A;  2W8F A;  2X00 D;  5AIN A;  2VL0 A;  4ZK1 A;  3RI5 A;  5J5H A;  4ILC A;  3EI0 A;  4TWF A;  2QC1 B;  4HFH A;  2XQ6 A;  2YOE A;  4LML A;  5J5G A;  4ZZC A;  5BW2 A;  4TWH A;  4D01 A;  4IL9 A;  4ZR6 A;  2XQA A;  3C84 A;  4QH1 A;  4HFB A;  4LMK A;  2XQ5 A;  5HEU A;  4A97 A;  2XQ7 A;  4QAB A;  5SYO A;  4ZRU A;  4IL4 A;  5HCJ A;  3RQU A;  4DBM A;  3UU5 A;  4QH5 A;  4AFH A;  5J5F A;  3JAF A;  3U8M A;  5L4H A;  2Y58 A;  3TLT A;  4BFQ A;  4ILA A;  4AFT A;  4HFI A;  3PMZ A;  3JAD A;  3UU8 A;  3ZKR A;  4ZZB A;  2PGZ A;  5CFB A;  2BG9 A;  2BYP A;  5CO5 A;  4ALX A;  4TNV A;  5KZU A;  4EZ1 A;  3WTJ A;  2X00 A;  4XHE A;  3WIP A;  3WTI A;  5LXB A;  2BJ0 A;  2UZ6 A;  2Y7Y A;  2XQ8 A;  3LSV A;  4ZK4 A;  4IRE A;  5AFK A;  2WZY A;  3UQ7 A;  4UM3 A;  1UW6 A;  2YME A;  2XZ5 A;  2ZJU A;  2Y57 A;  2WN9 A;  2Y54 A;  5AFN A;  3WTL A; 
#chains in the Genus database with same CATH homology
 3ZDH A;  4HFD A;  3EHZ A;  5TVC A;  2XYS A;  3JAE A;  4TNW A;  2BYR A;  4QAA A;  3TLS A;  5AFM A;  2WNJ A;  3P50 A;  4UY2 A;  3RHW A;  5HEJ A;  5AFJ A;  5IUX A;  3GUA A;  3EAM A;  2XQ3 A;  2XZ6 A;  4HFC A;  2XNV A;  3P4W A;  5L4E A;  4ILB A;  5HEH A;  4HFE A;  2WNL A;  2BR7 A;  1UV6 A;  2BG9 C;  3IGQ A;  2WNC A;  3WTK A;  4COF A;  4PIR A;  3UU3 A;  4UM1 A;  1I9B A;  3C79 A;  3RQW A;  3WTH A;  4QH4 A;  3U8N A;  2XYT A;  4XK9 A;  3TLU A;  4UXU A;  4UM3 P;  5BRX A;  5KE4 A;  5HEO A;  2YN6 A;  2XQ9 A;  2XNU A;  2W8G A;  2BR8 A;  2BG9 B;  2BYN A;  3PEO A;  4LMJ A;  5HEG A;  2ZJV A;  3WTN A;  2C9T A;  5AFH A;  4F8H A;  5J5I A;  3SQ6 A;  3RIA A;  2XQ4 A;  4NPP A;  4QAC A;  3SH1 A;  2YMD A;  2Y56 A;  5JME A;  3WTM A;  2BG9 E;  3UU4 A;  3WTO A;  3U8L A;  4HQP A;  3RIF A;  4AFG A;  3T4M A;  3UU6 A;  5LG3 A;  3TLV A;  4WV9 A;  3SIO A;  3SQ9 A;  2PH9 A;  4UM3 S;  1UX2 A;  4B5D A;  3UUB A;  3ZDG A;  5BP0 A;  5FJV A;  5J0Z A;  4A98 A;  4BQT A;  3TLW A;  2XNT A;  4X5T A;  2YKS A;  5AFM B;  2BYQ A;  4FRR A;  4NZB A;  4Z91 A;  3U8K A;  5L47 A;  3UQ4 A;  4TWD A;  3U8J A;  2BYS A;  5HCM A;  4ZJT A;  5AFL A;  4ZJS A;  4Z90 A;  2W8F A;  2X00 D;  5AIN A;  2VL0 A;  4ZK1 A;  3RI5 A;  5J5H A;  4ILC A;  3EI0 A;  4TWF A;  2QC1 B;  4HFH A;  2XQ6 A;  2YOE A;  4LML A;  5J5G A;  4ZZC A;  5BW2 A;  4TWH A;  4D01 A;  4IL9 A;  4ZR6 A;  2XQA A;  3C84 A;  4QH1 A;  4HFB A;  4LMK A;  2XQ5 A;  5HEU A;  4A97 A;  2XQ7 A;  4QAB A;  5SYO A;  4ZRU A;  4IL4 A;  5HCJ A;  3RQU A;  4DBM A;  3UU5 A;  4QH5 A;  4AFH A;  5J5F A;  3JAF A;  3U8M A;  5L4H A;  2Y58 A;  3TLT A;  4BFQ A;  4ILA A;  4AFT A;  4HFI A;  3PMZ A;  3JAD A;  3UU8 A;  3ZKR A;  4ZZB A;  2PGZ A;  5CFB A;  2BG9 A;  2BYP A;  5CO5 A;  4ALX A;  4TNV A;  5KZU A;  4EZ1 A;  3WTJ A;  2X00 A;  4XHE A;  3WIP A;  3WTI A;  5LXB A;  2BJ0 A;  2UZ6 A;  2Y7Y A;  2XQ8 A;  3LSV A;  4ZK4 A;  4IRE A;  5AFK A;  2WZY A;  3UQ7 A;  4UM3 A;  1UW6 A;  2YME A;  2XZ5 A;  2ZJU A;  2Y57 A;  2WN9 A;  2Y54 A;  5AFN A;  3WTL A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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3WIPA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations