3WTI | Genus

Total Genus 46

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	46
sequence length	207
structure length	207
Chain Sequence	ADRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQRTTWSDRTLAWDSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Signaling protein
source organism	Lymnaea stagnalis
publication title	Studies on an acetylcholine binding protein identify a basic residue in loop G on the beta 1 strand as a new structural determinant of neonicotinoid actions pubmed doi rcsb
molecule keywords	Acetylcholine-binding protein
total genus	46
structure length	207
sequence length	207
chains with identical sequence	B, C, D, E
ec nomenclature
pdb deposition date	2014-04-11

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF02931	Neur_chan_LBD	Neurotransmitter-gated ion-channel ligand binding domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.70.170.10	Mainly Beta	Distorted Sandwich	Acetylcholine Binding Protein; Chain: A,	Neurotransmitter-gated ion-channel ligand-binding domain	3wtiA00

5HEOA 2C9TA 4LMJA 2WNJA 5SYOA 2WNCA 3WTNA 5AFMA 4ZZCA 4XHEA 3EI0A 5HEHA 4BQTA 4NPPA 5BP0A 2BG9E 4PIRA 4ZK4A 2VL0A 4QH1A 4Z90A 5AFNA 3TLTA 5FJVA 5HEJA 3RHWA 2BG9A 5CFBA 3RI5A 4UXUA 3UU8A 5AINA 5HEUA 3P50A 5AFMB 2BG9C 2BYPA 4HQPA 3TLSA 3UQ4A 3UQ7A 3T4MA 5KZUA 4QH4A 5L47A 3TLUA 3UU6A 2BYQA 2Y56A 4AFGA 5J5IA 5JMEA 2W8FA 2UZ6A 1I9BA 2QC1B 3WTLA 5LG3A 3C79A 5HEGA 2BG9B 4ALXA 4ZR6A 2W8GA 5J0ZA 4A98A 4WV9A 5LXBA 3SIOA 5KE4A 4NZBA 4TWDA 3WTOA 2XQ7A 5AFJA 2XQ9A 4IL9A 4QH5A 4AFHA 2BJ0A 4HFIA 2BYNA 3RQWA 4HFDA 4TWFA 2Y54A 3WIPA 3PMZA 4UM3S 3WTIA 4UM3A 2XQ4A 3U8NA 2BYSA 3IGQA 5L4HA 3WTJA 5CO5A 3UUBA 2WN9A 3C84A 3RIAA 4HFEA 4QAAA 3SQ9A 5AFKA 4ILCA 1UX2A 2BYRA 2ZJVA 4UM1A 2BR8A 4BFQA 4D01A 2YKSA 3EHZA 4HFHA 4TNWA 2XNVA 3P4WA 3JAFA 3U8KA 4XK9A 2X00A 3UU3A 5BRXA 2XQ3A 2XQ6A 4COFA 3U8JA 2XQ5A 3WTHA 4B5DA 4ILBA 4UM3P 5IUXA 4X5TA 5J5FA 5BW2A 2Y7YA 3WTKA 5AFHA 3RIFA 3WTMA 2XZ5A 2WZYA 3JAEA 5HCMA 3U8LA 3GUAA 2PGZA 4UY2A 4A97A 4LMKA 2XYSA 4TNVA 2Y57A 2YOEA 4QACA 2WNLA 4IREA 2YMDA 3TLWA 3ZDHA 3ZDGA 2XNUA 4ZZBA 5L4EA 1UV6A 3PEOA 2XYTA 2YN6A 4ZRUA 5HCJA 2BR7A 4ILAA 4EZ1A 3SQ6A 4AFTA 4HFBA 4ZJTA 3ZKRA 4HFCA 3RQUA 3JADA 2X00D 4FRRA 2YMEA 4DBMA 2XZ6A 3UU5A 3LSVA 4QABA 2PH9A 4ZK1A 2XQAA 5J5GA 2XQ8A 3SH1A 2Y58A 2ZJUA 4TWHA 4IL4A 5AFLA 3TLVA 5J5HA 1UW6A 4F8HA 4LMLA 5TVCA 3U8MA 4Z91A 3EAMA 3UU4A 2XNTA 4ZJSA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 5HEO A;  2C9T A;  4LMJ A;  2WNJ A;  5SYO A;  2WNC A;  3WTN A;  5AFM A;  4ZZC A;  4XHE A;  3EI0 A;  5HEH A;  4BQT A;  4NPP A;  5BP0 A;  2BG9 E;  4PIR A;  4ZK4 A;  2VL0 A;  4QH1 A;  4Z90 A;  5AFN A;  3TLT A;  5FJV A;  5HEJ A;  3RHW A;  2BG9 A;  5CFB A;  3RI5 A;  4UXU A;  3UU8 A;  5AIN A;  5HEU A;  3P50 A;  5AFM B;  2BG9 C;  2BYP A;  4HQP A;  3TLS A;  3UQ4 A;  3UQ7 A;  3T4M A;  5KZU A;  4QH4 A;  5L47 A;  3TLU A;  3UU6 A;  2BYQ A;  2Y56 A;  4AFG A;  5J5I A;  5JME A;  2W8F A;  2UZ6 A;  1I9B A;  2QC1 B;  3WTL A;  5LG3 A;  3C79 A;  5HEG A;  2BG9 B;  4ALX A;  4ZR6 A;  2W8G A;  5J0Z A;  4A98 A;  4WV9 A;  5LXB A;  3SIO A;  5KE4 A;  4NZB A;  4TWD A;  3WTO A;  2XQ7 A;  5AFJ A;  2XQ9 A;  4IL9 A;  4QH5 A;  4AFH A;  2BJ0 A;  4HFI A;  2BYN A;  3RQW A;  4HFD A;  4TWF A;  2Y54 A;  3WIP A;  3PMZ A;  4UM3 S;  3WTI A;  4UM3 A;  2XQ4 A;  3U8N A;  2BYS A;  3IGQ A;  5L4H A;  3WTJ A;  5CO5 A;  3UUB A;  2WN9 A;  3C84 A;  3RIA A;  4HFE A;  4QAA A;  3SQ9 A;  5AFK A;  4ILC A;  1UX2 A;  2BYR A;  2ZJV A;  4UM1 A;  2BR8 A;  4BFQ A;  4D01 A;  2YKS A;  3EHZ A;  4HFH A;  4TNW A;  2XNV A;  3P4W A;  3JAF A;  3U8K A;  4XK9 A;  2X00 A;  3UU3 A;  5BRX A;  2XQ3 A;  2XQ6 A;  4COF A;  3U8J A;  2XQ5 A;  3WTH A;  4B5D A;  4ILB A;  4UM3 P;  5IUX A;  4X5T A;  5J5F A;  5BW2 A;  2Y7Y A;  3WTK A;  5AFH A;  3RIF A;  3WTM A;  2XZ5 A;  2WZY A;  3JAE A;  5HCM A;  3U8L A;  3GUA A;  2PGZ A;  4UY2 A;  4A97 A;  4LMK A;  2XYS A;  4TNV A;  2Y57 A;  2YOE A;  4QAC A;  2WNL A;  4IRE A;  2YMD A;  3TLW A;  3ZDH A;  3ZDG A;  2XNU A;  4ZZB A;  5L4E A;  1UV6 A;  3PEO A;  2XYT A;  2YN6 A;  4ZRU A;  5HCJ A;  2BR7 A;  4ILA A;  4EZ1 A;  3SQ6 A;  4AFT A;  4HFB A;  4ZJT A;  3ZKR A;  4HFC A;  3RQU A;  3JAD A;  2X00 D;  4FRR A;  2YME A;  4DBM A;  2XZ6 A;  3UU5 A;  3LSV A;  4QAB A;  2PH9 A;  4ZK1 A;  2XQA A;  5J5G A;  2XQ8 A;  3SH1 A;  2Y58 A;  2ZJU A;  4TWH A;  4IL4 A;  5AFL A;  3TLV A;  5J5H A;  1UW6 A;  4F8H A;  4LML A;  5TVC A;  3U8M A;  4Z91 A;  3EAM A;  3UU4 A;  2XNT A;  4ZJS A; 
#chains in the Genus database with same CATH topology
 5HEO A;  2C9T A;  4LMJ A;  2WNJ A;  5SYO A;  2WNC A;  3WTN A;  5AFM A;  4ZZC A;  4XHE A;  3EI0 A;  5HEH A;  4BQT A;  4NPP A;  5BP0 A;  2BG9 E;  4PIR A;  4ZK4 A;  2VL0 A;  4QH1 A;  4Z90 A;  5AFN A;  3TLT A;  5FJV A;  5HEJ A;  3RHW A;  2BG9 A;  5CFB A;  3RI5 A;  4UXU A;  3UU8 A;  5AIN A;  5HEU A;  3P50 A;  5AFM B;  2BG9 C;  2BYP A;  4HQP A;  3TLS A;  3UQ4 A;  3UQ7 A;  3T4M A;  5KZU A;  4QH4 A;  5L47 A;  3TLU A;  3UU6 A;  2BYQ A;  2Y56 A;  4AFG A;  5J5I A;  5JME A;  2W8F A;  2UZ6 A;  1I9B A;  2QC1 B;  3WTL A;  5LG3 A;  3C79 A;  5HEG A;  2BG9 B;  4ALX A;  4ZR6 A;  2W8G A;  5J0Z A;  4A98 A;  4WV9 A;  5LXB A;  3SIO A;  5KE4 A;  4NZB A;  4TWD A;  3WTO A;  2XQ7 A;  5AFJ A;  2XQ9 A;  4IL9 A;  4QH5 A;  4AFH A;  2BJ0 A;  4HFI A;  2BYN A;  3RQW A;  4HFD A;  4TWF A;  2Y54 A;  3WIP A;  3PMZ A;  4UM3 S;  3WTI A;  4UM3 A;  2XQ4 A;  3U8N A;  2BYS A;  3IGQ A;  5L4H A;  3WTJ A;  5CO5 A;  3UUB A;  2WN9 A;  3C84 A;  3RIA A;  4HFE A;  4QAA A;  3SQ9 A;  5AFK A;  4ILC A;  1UX2 A;  2BYR A;  2ZJV A;  4UM1 A;  2BR8 A;  4BFQ A;  4D01 A;  2YKS A;  3EHZ A;  4HFH A;  4TNW A;  2XNV A;  3P4W A;  3JAF A;  3U8K A;  4XK9 A;  2X00 A;  3UU3 A;  5BRX A;  2XQ3 A;  2XQ6 A;  4COF A;  3U8J A;  2XQ5 A;  3WTH A;  4B5D A;  4ILB A;  4UM3 P;  5IUX A;  4X5T A;  5J5F A;  5BW2 A;  2Y7Y A;  3WTK A;  5AFH A;  3RIF A;  3WTM A;  2XZ5 A;  2WZY A;  3JAE A;  5HCM A;  3U8L A;  3GUA A;  2PGZ A;  4UY2 A;  4A97 A;  4LMK A;  2XYS A;  4TNV A;  2Y57 A;  2YOE A;  4QAC A;  2WNL A;  4IRE A;  2YMD A;  3TLW A;  3ZDH A;  3ZDG A;  2XNU A;  4ZZB A;  5L4E A;  1UV6 A;  3PEO A;  2XYT A;  2YN6 A;  4ZRU A;  5HCJ A;  2BR7 A;  4ILA A;  4EZ1 A;  3SQ6 A;  4AFT A;  4HFB A;  4ZJT A;  3ZKR A;  4HFC A;  3RQU A;  3JAD A;  2X00 D;  4FRR A;  2YME A;  4DBM A;  2XZ6 A;  3UU5 A;  3LSV A;  4QAB A;  2PH9 A;  4ZK1 A;  2XQA A;  5J5G A;  2XQ8 A;  3SH1 A;  2Y58 A;  2ZJU A;  4TWH A;  4IL4 A;  5AFL A;  3TLV A;  5J5H A;  1UW6 A;  4F8H A;  4LML A;  5TVC A;  3U8M A;  4Z91 A;  3EAM A;  3UU4 A;  2XNT A;  4ZJS A; 
#chains in the Genus database with same CATH homology
 5HEO A;  2C9T A;  4LMJ A;  2WNJ A;  5SYO A;  2WNC A;  3WTN A;  5AFM A;  4ZZC A;  4XHE A;  3EI0 A;  5HEH A;  4BQT A;  4NPP A;  5BP0 A;  2BG9 E;  4PIR A;  4ZK4 A;  2VL0 A;  4QH1 A;  4Z90 A;  5AFN A;  3TLT A;  5FJV A;  5HEJ A;  3RHW A;  2BG9 A;  5CFB A;  3RI5 A;  4UXU A;  3UU8 A;  5AIN A;  5HEU A;  3P50 A;  5AFM B;  2BG9 C;  2BYP A;  4HQP A;  3TLS A;  3UQ4 A;  3UQ7 A;  3T4M A;  5KZU A;  4QH4 A;  5L47 A;  3TLU A;  3UU6 A;  2BYQ A;  2Y56 A;  4AFG A;  5J5I A;  5JME A;  2W8F A;  2UZ6 A;  1I9B A;  2QC1 B;  3WTL A;  5LG3 A;  3C79 A;  5HEG A;  2BG9 B;  4ALX A;  4ZR6 A;  2W8G A;  5J0Z A;  4A98 A;  4WV9 A;  5LXB A;  3SIO A;  5KE4 A;  4NZB A;  4TWD A;  3WTO A;  2XQ7 A;  5AFJ A;  2XQ9 A;  4IL9 A;  4QH5 A;  4AFH A;  2BJ0 A;  4HFI A;  2BYN A;  3RQW A;  4HFD A;  4TWF A;  2Y54 A;  3WIP A;  3PMZ A;  4UM3 S;  3WTI A;  4UM3 A;  2XQ4 A;  3U8N A;  2BYS A;  3IGQ A;  5L4H A;  3WTJ A;  5CO5 A;  3UUB A;  2WN9 A;  3C84 A;  3RIA A;  4HFE A;  4QAA A;  3SQ9 A;  5AFK A;  4ILC A;  1UX2 A;  2BYR A;  2ZJV A;  4UM1 A;  2BR8 A;  4BFQ A;  4D01 A;  2YKS A;  3EHZ A;  4HFH A;  4TNW A;  2XNV A;  3P4W A;  3JAF A;  3U8K A;  4XK9 A;  2X00 A;  3UU3 A;  5BRX A;  2XQ3 A;  2XQ6 A;  4COF A;  3U8J A;  2XQ5 A;  3WTH A;  4B5D A;  4ILB A;  4UM3 P;  5IUX A;  4X5T A;  5J5F A;  5BW2 A;  2Y7Y A;  3WTK A;  5AFH A;  3RIF A;  3WTM A;  2XZ5 A;  2WZY A;  3JAE A;  5HCM A;  3U8L A;  3GUA A;  2PGZ A;  4UY2 A;  4A97 A;  4LMK A;  2XYS A;  4TNV A;  2Y57 A;  2YOE A;  4QAC A;  2WNL A;  4IRE A;  2YMD A;  3TLW A;  3ZDH A;  3ZDG A;  2XNU A;  4ZZB A;  5L4E A;  1UV6 A;  3PEO A;  2XYT A;  2YN6 A;  4ZRU A;  5HCJ A;  2BR7 A;  4ILA A;  4EZ1 A;  3SQ6 A;  4AFT A;  4HFB A;  4ZJT A;  3ZKR A;  4HFC A;  3RQU A;  3JAD A;  2X00 D;  4FRR A;  2YME A;  4DBM A;  2XZ6 A;  3UU5 A;  3LSV A;  4QAB A;  2PH9 A;  4ZK1 A;  2XQA A;  5J5G A;  2XQ8 A;  3SH1 A;  2Y58 A;  2ZJU A;  4TWH A;  4IL4 A;  5AFL A;  3TLV A;  5J5H A;  1UW6 A;  4F8H A;  4LML A;  5TVC A;  3U8M A;  4Z91 A;  3EAM A;  3UU4 A;  2XNT A;  4ZJS A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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3WTIA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations