3WTLA

Crystal structure of lymnaea stagnalis acetylcholine binding protein complexed with nitromethylene analogue of imidacloprid
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
208
structure length
208
Chain Sequence
AADRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWDSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Studies on an acetylcholine binding protein identify a basic residue in loop G on the beta 1 strand as a new structural determinant of neonicotinoid actions
pubmed doi rcsb
molecule tags Signaling protein
source organism Lymnaea stagnalis
molecule keywords Acetylcholine-binding protein
total genus 52
structure length 208
sequence length 208
chains with identical sequence B, C, D, E
ec nomenclature
pdb deposition date 2014-04-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 3wtlA00
5J5IA 4UY2A 2BR8A 3RIFA 5HCMA 3UQ4A 2ZJUA 3WTHA 4QABA 5AFMB 4LMKA 3UQ7A 4XHEA 2ZJVA 5HCJA 3TLSA 4ZRUA 4AFGA 4UM3P 3UU4A 3U8MA 5SYOA 4HFDA 2VL0A 2UZ6A 4ZZCA 4D01A 2PH9A 4ZZBA 2BR7A 4LMLA 2XYTA 2XNVA 5L4HA 4NPPA 3SH1A 2WN9A 2XYSA 4QH4A 3WTIA 5L4EA 3UU3A 3P4WA 4HFCA 3UU5A 3U8LA 3WTLA 4FRRA 2Y54A 3C79A 2XZ5A 4IREA 2XNUA 4QH5A 5FJVA 5J0ZA 5AFHA 1UV6A 5LXBA 4UXUA 2BG9B 5IUXA 2YMDA 5BP0A 3GUAA 3TLTA 3PMZA 4ILCA 3ZKRA 3WTOA 3P50A 3C84A 2C9TA 4ZJSA 1I9BA 5TVCA 4HFBA 3SQ9A 2PGZA 2BG9C 4ZK4A 4A97A 2XQ3A 4QAAA 3EHZA 3U8KA 2BJ0A 3JADA 2Y58A 5J5FA 2WNLA 4ZJTA 4HFEA 2XQ7A 2XQ9A 4PIRA 2BYQA 2XQ6A 2Y57A 4HFIA 4TNVA 5HEUA 3EI0A 4AFTA 4HFHA 4BFQA 5BW2A 4COFA 5AFKA 5BRXA 3ZDGA 3RIAA 5CFBA 4ALXA 3IGQA 2YN6A 3JAEA 1UW6A 4ZK1A 2BYSA 4TWDA 5AFMA 4B5DA 3WTNA 4ILAA 3SQ6A 4BQTA 2XZ6A 3RHWA 4F8HA 2YKSA 4A98A 5KZUA 3U8JA 5CO5A 4HQPA 5HEOA 5AINA 5LG3A 5J5HA 3PEOA 3TLVA 3TLWA 5L47A 4IL9A 3WTJA 3SIOA 4TNWA 4UM3A 2YMEA 5J5GA 2W8GA 2X00D 4TWHA 5HEHA 5HEGA 4UM3S 5AFLA 3WTKA 4Z91A 3ZDHA 2Y56A 4QACA 4UM1A 3UU6A 2WNJA 5JMEA 2BG9A 4Z90A 2W8FA 4TWFA 5AFJA 2QC1B 2XQAA 4NZBA 5KE4A 2XNTA 1UX2A 3U8NA 4XK9A 4QH1A 3RQWA 3T4MA 4LMJA 2BYNA 3WIPA 3EAMA 2BYRA 3LSVA 2X00A 5HEJA 2YOEA 2XQ4A 4WV9A 3JAFA 3RQUA 4IL4A 3UUBA 4DBMA 2XQ5A 5AFNA 4X5TA 3TLUA 2BG9E 2XQ8A 4AFHA 3RI5A 4EZ1A 4ZR6A 4ILBA 3UU8A 2WNCA 2WZYA 2BYPA 2Y7YA 3WTMA
chains in the Genus database with same CATH superfamily
5J5IA 4UY2A 2BR8A 3RIFA 5HCMA 3UQ4A 2ZJUA 3WTHA 4QABA 5AFMB 4LMKA 3UQ7A 4XHEA 2ZJVA 5HCJA 3TLSA 4ZRUA 4AFGA 4UM3P 3UU4A 3U8MA 5SYOA 4HFDA 2VL0A 2UZ6A 4ZZCA 4D01A 2PH9A 4ZZBA 2BR7A 4LMLA 2XYTA 2XNVA 5L4HA 4NPPA 3SH1A 2WN9A 2XYSA 4QH4A 3WTIA 5L4EA 3UU3A 3P4WA 4HFCA 3UU5A 3U8LA 3WTLA 4FRRA 2Y54A 3C79A 2XZ5A 4IREA 2XNUA 4QH5A 5FJVA 5J0ZA 5AFHA 1UV6A 5LXBA 4UXUA 2BG9B 5IUXA 2YMDA 5BP0A 3GUAA 3TLTA 3PMZA 4ILCA 3ZKRA 3WTOA 3P50A 3C84A 2C9TA 4ZJSA 1I9BA 5TVCA 4HFBA 3SQ9A 2PGZA 2BG9C 4ZK4A 4A97A 2XQ3A 4QAAA 3EHZA 3U8KA 2BJ0A 3JADA 2Y58A 5J5FA 2WNLA 4ZJTA 4HFEA 2XQ7A 2XQ9A 4PIRA 2BYQA 2XQ6A 2Y57A 4HFIA 4TNVA 5HEUA 3EI0A 4AFTA 4HFHA 4BFQA 5BW2A 4COFA 5AFKA 5BRXA 3ZDGA 3RIAA 5CFBA 4ALXA 3IGQA 2YN6A 3JAEA 1UW6A 4ZK1A 2BYSA 4TWDA 5AFMA 4B5DA 3WTNA 4ILAA 3SQ6A 4BQTA 2XZ6A 3RHWA 4F8HA 2YKSA 4A98A 5KZUA 3U8JA 5CO5A 4HQPA 5HEOA 5AINA 5LG3A 5J5HA 3PEOA 3TLVA 3TLWA 5L47A 4IL9A 3WTJA 3SIOA 4TNWA 4UM3A 2YMEA 5J5GA 2W8GA 2X00D 4TWHA 5HEHA 5HEGA 4UM3S 5AFLA 3WTKA 4Z91A 3ZDHA 2Y56A 4QACA 4UM1A 3UU6A 2WNJA 5JMEA 2BG9A 4Z90A 2W8FA 4TWFA 5AFJA 2QC1B 2XQAA 4NZBA 5KE4A 2XNTA 1UX2A 3U8NA 4XK9A 4QH1A 3RQWA 3T4MA 4LMJA 2BYNA 3WIPA 3EAMA 2BYRA 3LSVA 2X00A 5HEJA 2YOEA 2XQ4A 4WV9A 3JAFA 3RQUA 4IL4A 3UUBA 4DBMA 2XQ5A 5AFNA 4X5TA 3TLUA 2BG9E 2XQ8A 4AFHA 3RI5A 4EZ1A 4ZR6A 4ILBA 3UU8A 2WNCA 2WZYA 2BYPA 2Y7YA 3WTMA
chains in the Genus database with same CATH topology
5J5IA 4UY2A 2BR8A 3RIFA 5HCMA 3UQ4A 2ZJUA 3WTHA 4QABA 5AFMB 4LMKA 3UQ7A 4XHEA 2ZJVA 5HCJA 3TLSA 4ZRUA 4AFGA 4UM3P 3UU4A 3U8MA 5SYOA 4HFDA 2VL0A 2UZ6A 4ZZCA 4D01A 2PH9A 4ZZBA 2BR7A 4LMLA 2XYTA 2XNVA 5L4HA 4NPPA 3SH1A 2WN9A 2XYSA 4QH4A 3WTIA 5L4EA 3UU3A 3P4WA 4HFCA 3UU5A 3U8LA 3WTLA 4FRRA 2Y54A 3C79A 2XZ5A 4IREA 2XNUA 4QH5A 5FJVA 5J0ZA 5AFHA 1UV6A 5LXBA 4UXUA 2BG9B 5IUXA 2YMDA 5BP0A 3GUAA 3TLTA 3PMZA 4ILCA 3ZKRA 3WTOA 3P50A 3C84A 2C9TA 4ZJSA 1I9BA 5TVCA 4HFBA 3SQ9A 2PGZA 2BG9C 4ZK4A 4A97A 2XQ3A 4QAAA 3EHZA 3U8KA 2BJ0A 3JADA 2Y58A 5J5FA 2WNLA 4ZJTA 4HFEA 2XQ7A 2XQ9A 4PIRA 2BYQA 2XQ6A 2Y57A 4HFIA 4TNVA 5HEUA 3EI0A 4AFTA 4HFHA 4BFQA 5BW2A 4COFA 5AFKA 5BRXA 3ZDGA 3RIAA 5CFBA 4ALXA 3IGQA 2YN6A 3JAEA 1UW6A 4ZK1A 2BYSA 4TWDA 5AFMA 4B5DA 3WTNA 4ILAA 3SQ6A 4BQTA 2XZ6A 3RHWA 4F8HA 2YKSA 4A98A 5KZUA 3U8JA 5CO5A 4HQPA 5HEOA 5AINA 5LG3A 5J5HA 3PEOA 3TLVA 3TLWA 5L47A 4IL9A 3WTJA 3SIOA 4TNWA 4UM3A 2YMEA 5J5GA 2W8GA 2X00D 4TWHA 5HEHA 5HEGA 4UM3S 5AFLA 3WTKA 4Z91A 3ZDHA 2Y56A 4QACA 4UM1A 3UU6A 2WNJA 5JMEA 2BG9A 4Z90A 2W8FA 4TWFA 5AFJA 2QC1B 2XQAA 4NZBA 5KE4A 2XNTA 1UX2A 3U8NA 4XK9A 4QH1A 3RQWA 3T4MA 4LMJA 2BYNA 3WIPA 3EAMA 2BYRA 3LSVA 2X00A 5HEJA 2YOEA 2XQ4A 4WV9A 3JAFA 3RQUA 4IL4A 3UUBA 4DBMA 2XQ5A 5AFNA 4X5TA 3TLUA 2BG9E 2XQ8A 4AFHA 3RI5A 4EZ1A 4ZR6A 4ILBA 3UU8A 2WNCA 2WZYA 2BYPA 2Y7YA 3WTMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5J5I A;  4UY2 A;  2BR8 A;  3RIF A;  5HCM A;  3UQ4 A;  2ZJU A;  3WTH A;  4QAB A;  5AFM B;  4LMK A;  3UQ7 A;  4XHE A;  2ZJV A;  5HCJ A;  3TLS A;  4ZRU A;  4AFG A;  4UM3 P;  3UU4 A;  3U8M A;  5SYO A;  4HFD A;  2VL0 A;  2UZ6 A;  4ZZC A;  4D01 A;  2PH9 A;  4ZZB A;  2BR7 A;  4LML A;  2XYT A;  2XNV A;  5L4H A;  4NPP A;  3SH1 A;  2WN9 A;  2XYS A;  4QH4 A;  3WTI A;  5L4E A;  3UU3 A;  3P4W A;  4HFC A;  3UU5 A;  3U8L A;  3WTL A;  4FRR A;  2Y54 A;  3C79 A;  2XZ5 A;  4IRE A;  2XNU A;  4QH5 A;  5FJV A;  5J0Z A;  5AFH A;  1UV6 A;  5LXB A;  4UXU A;  2BG9 B;  5IUX A;  2YMD A;  5BP0 A;  3GUA A;  3TLT A;  3PMZ A;  4ILC A;  3ZKR A;  3WTO A;  3P50 A;  3C84 A;  2C9T A;  4ZJS A;  1I9B A;  5TVC A;  4HFB A;  3SQ9 A;  2PGZ A;  2BG9 C;  4ZK4 A;  4A97 A;  2XQ3 A;  4QAA A;  3EHZ A;  3U8K A;  2BJ0 A;  3JAD A;  2Y58 A;  5J5F A;  2WNL A;  4ZJT A;  4HFE A;  2XQ7 A;  2XQ9 A;  4PIR A;  2BYQ A;  2XQ6 A;  2Y57 A;  4HFI A;  4TNV A;  5HEU A;  3EI0 A;  4AFT A;  4HFH A;  4BFQ A;  5BW2 A;  4COF A;  5AFK A;  5BRX A;  3ZDG A;  3RIA A;  5CFB A;  4ALX A;  3IGQ A;  2YN6 A;  3JAE A;  1UW6 A;  4ZK1 A;  2BYS A;  4TWD A;  5AFM A;  4B5D A;  3WTN A;  4ILA A;  3SQ6 A;  4BQT A;  2XZ6 A;  3RHW A;  4F8H A;  2YKS A;  4A98 A;  5KZU A;  3U8J A;  5CO5 A;  4HQP A;  5HEO A;  5AIN A;  5LG3 A;  5J5H A;  3PEO A;  3TLV A;  3TLW A;  5L47 A;  4IL9 A;  3WTJ A;  3SIO A;  4TNW A;  4UM3 A;  2YME A;  5J5G A;  2W8G A;  2X00 D;  4TWH A;  5HEH A;  5HEG A;  4UM3 S;  5AFL A;  3WTK A;  4Z91 A;  3ZDH A;  2Y56 A;  4QAC A;  4UM1 A;  3UU6 A;  2WNJ A;  5JME A;  2BG9 A;  4Z90 A;  2W8F A;  4TWF A;  5AFJ A;  2QC1 B;  2XQA A;  4NZB A;  5KE4 A;  2XNT A;  1UX2 A;  3U8N A;  4XK9 A;  4QH1 A;  3RQW A;  3T4M A;  4LMJ A;  2BYN A;  3WIP A;  3EAM A;  2BYR A;  3LSV A;  2X00 A;  5HEJ A;  2YOE A;  2XQ4 A;  4WV9 A;  3JAF A;  3RQU A;  4IL4 A;  3UUB A;  4DBM A;  2XQ5 A;  5AFN A;  4X5T A;  3TLU A;  2BG9 E;  2XQ8 A;  4AFH A;  3RI5 A;  4EZ1 A;  4ZR6 A;  4ILB A;  3UU8 A;  2WNC A;  2WZY A;  2BYP A;  2Y7Y A;  3WTM A; 
#chains in the Genus database with same CATH topology
 5J5I A;  4UY2 A;  2BR8 A;  3RIF A;  5HCM A;  3UQ4 A;  2ZJU A;  3WTH A;  4QAB A;  5AFM B;  4LMK A;  3UQ7 A;  4XHE A;  2ZJV A;  5HCJ A;  3TLS A;  4ZRU A;  4AFG A;  4UM3 P;  3UU4 A;  3U8M A;  5SYO A;  4HFD A;  2VL0 A;  2UZ6 A;  4ZZC A;  4D01 A;  2PH9 A;  4ZZB A;  2BR7 A;  4LML A;  2XYT A;  2XNV A;  5L4H A;  4NPP A;  3SH1 A;  2WN9 A;  2XYS A;  4QH4 A;  3WTI A;  5L4E A;  3UU3 A;  3P4W A;  4HFC A;  3UU5 A;  3U8L A;  3WTL A;  4FRR A;  2Y54 A;  3C79 A;  2XZ5 A;  4IRE A;  2XNU A;  4QH5 A;  5FJV A;  5J0Z A;  5AFH A;  1UV6 A;  5LXB A;  4UXU A;  2BG9 B;  5IUX A;  2YMD A;  5BP0 A;  3GUA A;  3TLT A;  3PMZ A;  4ILC A;  3ZKR A;  3WTO A;  3P50 A;  3C84 A;  2C9T A;  4ZJS A;  1I9B A;  5TVC A;  4HFB A;  3SQ9 A;  2PGZ A;  2BG9 C;  4ZK4 A;  4A97 A;  2XQ3 A;  4QAA A;  3EHZ A;  3U8K A;  2BJ0 A;  3JAD A;  2Y58 A;  5J5F A;  2WNL A;  4ZJT A;  4HFE A;  2XQ7 A;  2XQ9 A;  4PIR A;  2BYQ A;  2XQ6 A;  2Y57 A;  4HFI A;  4TNV A;  5HEU A;  3EI0 A;  4AFT A;  4HFH A;  4BFQ A;  5BW2 A;  4COF A;  5AFK A;  5BRX A;  3ZDG A;  3RIA A;  5CFB A;  4ALX A;  3IGQ A;  2YN6 A;  3JAE A;  1UW6 A;  4ZK1 A;  2BYS A;  4TWD A;  5AFM A;  4B5D A;  3WTN A;  4ILA A;  3SQ6 A;  4BQT A;  2XZ6 A;  3RHW A;  4F8H A;  2YKS A;  4A98 A;  5KZU A;  3U8J A;  5CO5 A;  4HQP A;  5HEO A;  5AIN A;  5LG3 A;  5J5H A;  3PEO A;  3TLV A;  3TLW A;  5L47 A;  4IL9 A;  3WTJ A;  3SIO A;  4TNW A;  4UM3 A;  2YME A;  5J5G A;  2W8G A;  2X00 D;  4TWH A;  5HEH A;  5HEG A;  4UM3 S;  5AFL A;  3WTK A;  4Z91 A;  3ZDH A;  2Y56 A;  4QAC A;  4UM1 A;  3UU6 A;  2WNJ A;  5JME A;  2BG9 A;  4Z90 A;  2W8F A;  4TWF A;  5AFJ A;  2QC1 B;  2XQA A;  4NZB A;  5KE4 A;  2XNT A;  1UX2 A;  3U8N A;  4XK9 A;  4QH1 A;  3RQW A;  3T4M A;  4LMJ A;  2BYN A;  3WIP A;  3EAM A;  2BYR A;  3LSV A;  2X00 A;  5HEJ A;  2YOE A;  2XQ4 A;  4WV9 A;  3JAF A;  3RQU A;  4IL4 A;  3UUB A;  4DBM A;  2XQ5 A;  5AFN A;  4X5T A;  3TLU A;  2BG9 E;  2XQ8 A;  4AFH A;  3RI5 A;  4EZ1 A;  4ZR6 A;  4ILB A;  3UU8 A;  2WNC A;  2WZY A;  2BYP A;  2Y7Y A;  3WTM A; 
#chains in the Genus database with same CATH homology
 5J5I A;  4UY2 A;  2BR8 A;  3RIF A;  5HCM A;  3UQ4 A;  2ZJU A;  3WTH A;  4QAB A;  5AFM B;  4LMK A;  3UQ7 A;  4XHE A;  2ZJV A;  5HCJ A;  3TLS A;  4ZRU A;  4AFG A;  4UM3 P;  3UU4 A;  3U8M A;  5SYO A;  4HFD A;  2VL0 A;  2UZ6 A;  4ZZC A;  4D01 A;  2PH9 A;  4ZZB A;  2BR7 A;  4LML A;  2XYT A;  2XNV A;  5L4H A;  4NPP A;  3SH1 A;  2WN9 A;  2XYS A;  4QH4 A;  3WTI A;  5L4E A;  3UU3 A;  3P4W A;  4HFC A;  3UU5 A;  3U8L A;  3WTL A;  4FRR A;  2Y54 A;  3C79 A;  2XZ5 A;  4IRE A;  2XNU A;  4QH5 A;  5FJV A;  5J0Z A;  5AFH A;  1UV6 A;  5LXB A;  4UXU A;  2BG9 B;  5IUX A;  2YMD A;  5BP0 A;  3GUA A;  3TLT A;  3PMZ A;  4ILC A;  3ZKR A;  3WTO A;  3P50 A;  3C84 A;  2C9T A;  4ZJS A;  1I9B A;  5TVC A;  4HFB A;  3SQ9 A;  2PGZ A;  2BG9 C;  4ZK4 A;  4A97 A;  2XQ3 A;  4QAA A;  3EHZ A;  3U8K A;  2BJ0 A;  3JAD A;  2Y58 A;  5J5F A;  2WNL A;  4ZJT A;  4HFE A;  2XQ7 A;  2XQ9 A;  4PIR A;  2BYQ A;  2XQ6 A;  2Y57 A;  4HFI A;  4TNV A;  5HEU A;  3EI0 A;  4AFT A;  4HFH A;  4BFQ A;  5BW2 A;  4COF A;  5AFK A;  5BRX A;  3ZDG A;  3RIA A;  5CFB A;  4ALX A;  3IGQ A;  2YN6 A;  3JAE A;  1UW6 A;  4ZK1 A;  2BYS A;  4TWD A;  5AFM A;  4B5D A;  3WTN A;  4ILA A;  3SQ6 A;  4BQT A;  2XZ6 A;  3RHW A;  4F8H A;  2YKS A;  4A98 A;  5KZU A;  3U8J A;  5CO5 A;  4HQP A;  5HEO A;  5AIN A;  5LG3 A;  5J5H A;  3PEO A;  3TLV A;  3TLW A;  5L47 A;  4IL9 A;  3WTJ A;  3SIO A;  4TNW A;  4UM3 A;  2YME A;  5J5G A;  2W8G A;  2X00 D;  4TWH A;  5HEH A;  5HEG A;  4UM3 S;  5AFL A;  3WTK A;  4Z91 A;  3ZDH A;  2Y56 A;  4QAC A;  4UM1 A;  3UU6 A;  2WNJ A;  5JME A;  2BG9 A;  4Z90 A;  2W8F A;  4TWF A;  5AFJ A;  2QC1 B;  2XQA A;  4NZB A;  5KE4 A;  2XNT A;  1UX2 A;  3U8N A;  4XK9 A;  4QH1 A;  3RQW A;  3T4M A;  4LMJ A;  2BYN A;  3WIP A;  3EAM A;  2BYR A;  3LSV A;  2X00 A;  5HEJ A;  2YOE A;  2XQ4 A;  4WV9 A;  3JAF A;  3RQU A;  4IL4 A;  3UUB A;  4DBM A;  2XQ5 A;  5AFN A;  4X5T A;  3TLU A;  2BG9 E;  2XQ8 A;  4AFH A;  3RI5 A;  4EZ1 A;  4ZR6 A;  4ILB A;  3UU8 A;  2WNC A;  2WZY A;  2BYP A;  2Y7Y A;  3WTM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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