3ZDGA

Crystal structure of ls-achbp complexed with carbamoylcholine analogue 3-(dimethylamino)butyl dimethylcarbamate (dmabc)
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
205
structure length
200
Chain Sequence
LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Synthesis, Pharmacology, and Biostructural Characterization of Novel Alpha(4)Beta(2) Nicotinic Acetylcholine Receptor Agonists.
pubmed doi rcsb
molecule tags Acetylcholine-binding protein
source organism Lymnaea stagnalis
molecule keywords ACETYLCHOLINE BINDING PROTEIN
total genus 48
structure length 200
sequence length 205
chains with identical sequence B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T
ec nomenclature
pdb deposition date 2012-11-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 3zdgA00
2WZYA 4UM1A 5J5GA 5BP0A 4AFHA 4IL9A 3LSVA 3TLTA 4EZ1A 5HCJA 4BFQA 4QH5A 2YOEA 3TLUA 5AINA 2XQ3A 5HCMA 3UU4A 3ZKRA 3RQWA 2XNTA 2UZ6A 4TWDA 5J5FA 2Y58A 2Y56A 4UY2A 3JADA 4X5TA 2WNLA 2XYSA 4HFDA 2ZJVA 3WTJA 2WNJA 2BJ0A 4LMKA 3WTLA 5FJVA 2XNUA 2YMDA 4QH4A 4ZK1A 2PGZA 3SQ6A 2C9TA 3UU3A 5AFMA 4Z90A 5AFKA 2Y7YA 2BG9B 2VL0A 5JMEA 2XNVA 2YN6A 3P4WA 4QAAA 5CFBA 5LG3A 3JAEA 4IREA 3UQ4A 3WTMA 1UV6A 2XQ5A 2XQ4A 3EAMA 3JAFA 3P50A 5HEHA 3U8LA 5AFNA 4TWHA 4UXUA 3RI5A 4HFIA 4ILCA 5HEUA 4HFBA 3UQ7A 4F8HA 3C84A 3EHZA 4XHEA 4IL4A 2BR8A 4UM3P 3U8KA 5L4EA 2Y57A 4COFA 5KZUA 5J0ZA 3SIOA 3RIAA 4TNWA 4TWFA 3UU8A 3U8JA 2XQ7A 2PH9A 2W8FA 2YMEA 2BG9C 4DBMA 3UUBA 3U8NA 4UM3A 3WTNA 3ZDGA 4AFTA 2XQ8A 3EI0A 4ILAA 3RHWA 4UM3S 4BQTA 5L47A 5CO5A 5TVCA 1UX2A 3U8MA 2XZ5A 1UW6A 4XK9A 4TNVA 2YKSA 4D01A 2BR7A 3T4MA 2XYTA 3WTKA 4A98A 4ZJTA 3WTIA 4NPPA 3RIFA 2X00A 2BYNA 3WIPA 3UU5A 3C79A 2XQ9A 4ZJSA 5J5HA 4ZK4A 3SH1A 2Y54A 2ZJUA 3PMZA 2BYQA 2WNCA 3PEOA 4LMLA 4QH1A 4WV9A 4AFGA 5BRXA 2XZ6A 5LXBA 4HFHA 4HFEA 5HEGA 5L4HA 5HEOA 2W8GA 2XQ6A 2BG9E 3RQUA 4PIRA 3WTOA 3TLSA 5SYOA 3SQ9A 4HFCA 4ZRUA 4ZZBA 4ZR6A 5AFJA 2BYRA 4B5DA 5AFHA 5J5IA 5AFLA 5AFMB 2BG9A 3IGQA 2X00D 4ZZCA 3GUAA 4ALXA 2BYPA 3TLWA 3UU6A 3ZDHA 3TLVA 5IUXA 2QC1B 2BYSA 2WN9A 4QACA 5HEJA 4FRRA 4A97A 4ILBA 4Z91A 4HQPA 4NZBA 1I9BA 4QABA 3WTHA 5BW2A 5KE4A 2XQAA 4LMJA
chains in the Genus database with same CATH superfamily
2WZYA 4UM1A 5J5GA 5BP0A 4AFHA 4IL9A 3LSVA 3TLTA 4EZ1A 5HCJA 4BFQA 4QH5A 2YOEA 3TLUA 5AINA 2XQ3A 5HCMA 3UU4A 3ZKRA 3RQWA 2XNTA 2UZ6A 4TWDA 5J5FA 2Y58A 2Y56A 4UY2A 3JADA 4X5TA 2WNLA 2XYSA 4HFDA 2ZJVA 3WTJA 2WNJA 2BJ0A 4LMKA 3WTLA 5FJVA 2XNUA 2YMDA 4QH4A 4ZK1A 2PGZA 3SQ6A 2C9TA 3UU3A 5AFMA 4Z90A 5AFKA 2Y7YA 2BG9B 2VL0A 5JMEA 2XNVA 2YN6A 3P4WA 4QAAA 5CFBA 5LG3A 3JAEA 4IREA 3UQ4A 3WTMA 1UV6A 2XQ5A 2XQ4A 3EAMA 3JAFA 3P50A 5HEHA 3U8LA 5AFNA 4TWHA 4UXUA 3RI5A 4HFIA 4ILCA 5HEUA 4HFBA 3UQ7A 4F8HA 3C84A 3EHZA 4XHEA 4IL4A 2BR8A 4UM3P 3U8KA 5L4EA 2Y57A 4COFA 5KZUA 5J0ZA 3SIOA 3RIAA 4TNWA 4TWFA 3UU8A 3U8JA 2XQ7A 2PH9A 2W8FA 2YMEA 2BG9C 4DBMA 3UUBA 3U8NA 4UM3A 3WTNA 3ZDGA 4AFTA 2XQ8A 3EI0A 4ILAA 3RHWA 4UM3S 4BQTA 5L47A 5CO5A 5TVCA 1UX2A 3U8MA 2XZ5A 1UW6A 4XK9A 4TNVA 2YKSA 4D01A 2BR7A 3T4MA 2XYTA 3WTKA 4A98A 4ZJTA 3WTIA 4NPPA 3RIFA 2X00A 2BYNA 3WIPA 3UU5A 3C79A 2XQ9A 4ZJSA 5J5HA 4ZK4A 3SH1A 2Y54A 2ZJUA 3PMZA 2BYQA 2WNCA 3PEOA 4LMLA 4QH1A 4WV9A 4AFGA 5BRXA 2XZ6A 5LXBA 4HFHA 4HFEA 5HEGA 5L4HA 5HEOA 2W8GA 2XQ6A 2BG9E 3RQUA 4PIRA 3WTOA 3TLSA 5SYOA 3SQ9A 4HFCA 4ZRUA 4ZZBA 4ZR6A 5AFJA 2BYRA 4B5DA 5AFHA 5J5IA 5AFLA 5AFMB 2BG9A 3IGQA 2X00D 4ZZCA 3GUAA 4ALXA 2BYPA 3TLWA 3UU6A 3ZDHA 3TLVA 5IUXA 2QC1B 2BYSA 2WN9A 4QACA 5HEJA 4FRRA 4A97A 4ILBA 4Z91A 4HQPA 4NZBA 1I9BA 4QABA 3WTHA 5BW2A 5KE4A 2XQAA 4LMJA
chains in the Genus database with same CATH topology
2WZYA 4UM1A 5J5GA 5BP0A 4AFHA 4IL9A 3LSVA 3TLTA 4EZ1A 5HCJA 4BFQA 4QH5A 2YOEA 3TLUA 5AINA 2XQ3A 5HCMA 3UU4A 3ZKRA 3RQWA 2XNTA 2UZ6A 4TWDA 5J5FA 2Y58A 2Y56A 4UY2A 3JADA 4X5TA 2WNLA 2XYSA 4HFDA 2ZJVA 3WTJA 2WNJA 2BJ0A 4LMKA 3WTLA 5FJVA 2XNUA 2YMDA 4QH4A 4ZK1A 2PGZA 3SQ6A 2C9TA 3UU3A 5AFMA 4Z90A 5AFKA 2Y7YA 2BG9B 2VL0A 5JMEA 2XNVA 2YN6A 3P4WA 4QAAA 5CFBA 5LG3A 3JAEA 4IREA 3UQ4A 3WTMA 1UV6A 2XQ5A 2XQ4A 3EAMA 3JAFA 3P50A 5HEHA 3U8LA 5AFNA 4TWHA 4UXUA 3RI5A 4HFIA 4ILCA 5HEUA 4HFBA 3UQ7A 4F8HA 3C84A 3EHZA 4XHEA 4IL4A 2BR8A 4UM3P 3U8KA 5L4EA 2Y57A 4COFA 5KZUA 5J0ZA 3SIOA 3RIAA 4TNWA 4TWFA 3UU8A 3U8JA 2XQ7A 2PH9A 2W8FA 2YMEA 2BG9C 4DBMA 3UUBA 3U8NA 4UM3A 3WTNA 3ZDGA 4AFTA 2XQ8A 3EI0A 4ILAA 3RHWA 4UM3S 4BQTA 5L47A 5CO5A 5TVCA 1UX2A 3U8MA 2XZ5A 1UW6A 4XK9A 4TNVA 2YKSA 4D01A 2BR7A 3T4MA 2XYTA 3WTKA 4A98A 4ZJTA 3WTIA 4NPPA 3RIFA 2X00A 2BYNA 3WIPA 3UU5A 3C79A 2XQ9A 4ZJSA 5J5HA 4ZK4A 3SH1A 2Y54A 2ZJUA 3PMZA 2BYQA 2WNCA 3PEOA 4LMLA 4QH1A 4WV9A 4AFGA 5BRXA 2XZ6A 5LXBA 4HFHA 4HFEA 5HEGA 5L4HA 5HEOA 2W8GA 2XQ6A 2BG9E 3RQUA 4PIRA 3WTOA 3TLSA 5SYOA 3SQ9A 4HFCA 4ZRUA 4ZZBA 4ZR6A 5AFJA 2BYRA 4B5DA 5AFHA 5J5IA 5AFLA 5AFMB 2BG9A 3IGQA 2X00D 4ZZCA 3GUAA 4ALXA 2BYPA 3TLWA 3UU6A 3ZDHA 3TLVA 5IUXA 2QC1B 2BYSA 2WN9A 4QACA 5HEJA 4FRRA 4A97A 4ILBA 4Z91A 4HQPA 4NZBA 1I9BA 4QABA 3WTHA 5BW2A 5KE4A 2XQAA 4LMJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WZY A;  4UM1 A;  5J5G A;  5BP0 A;  4AFH A;  4IL9 A;  3LSV A;  3TLT A;  4EZ1 A;  5HCJ A;  4BFQ A;  4QH5 A;  2YOE A;  3TLU A;  5AIN A;  2XQ3 A;  5HCM A;  3UU4 A;  3ZKR A;  3RQW A;  2XNT A;  2UZ6 A;  4TWD A;  5J5F A;  2Y58 A;  2Y56 A;  4UY2 A;  3JAD A;  4X5T A;  2WNL A;  2XYS A;  4HFD A;  2ZJV A;  3WTJ A;  2WNJ A;  2BJ0 A;  4LMK A;  3WTL A;  5FJV A;  2XNU A;  2YMD A;  4QH4 A;  4ZK1 A;  2PGZ A;  3SQ6 A;  2C9T A;  3UU3 A;  5AFM A;  4Z90 A;  5AFK A;  2Y7Y A;  2BG9 B;  2VL0 A;  5JME A;  2XNV A;  2YN6 A;  3P4W A;  4QAA A;  5CFB A;  5LG3 A;  3JAE A;  4IRE A;  3UQ4 A;  3WTM A;  1UV6 A;  2XQ5 A;  2XQ4 A;  3EAM A;  3JAF A;  3P50 A;  5HEH A;  3U8L A;  5AFN A;  4TWH A;  4UXU A;  3RI5 A;  4HFI A;  4ILC A;  5HEU A;  4HFB A;  3UQ7 A;  4F8H A;  3C84 A;  3EHZ A;  4XHE A;  4IL4 A;  2BR8 A;  4UM3 P;  3U8K A;  5L4E A;  2Y57 A;  4COF A;  5KZU A;  5J0Z A;  3SIO A;  3RIA A;  4TNW A;  4TWF A;  3UU8 A;  3U8J A;  2XQ7 A;  2PH9 A;  2W8F A;  2YME A;  2BG9 C;  4DBM A;  3UUB A;  3U8N A;  4UM3 A;  3WTN A;  3ZDG A;  4AFT A;  2XQ8 A;  3EI0 A;  4ILA A;  3RHW A;  4UM3 S;  4BQT A;  5L47 A;  5CO5 A;  5TVC A;  1UX2 A;  3U8M A;  2XZ5 A;  1UW6 A;  4XK9 A;  4TNV A;  2YKS A;  4D01 A;  2BR7 A;  3T4M A;  2XYT A;  3WTK A;  4A98 A;  4ZJT A;  3WTI A;  4NPP A;  3RIF A;  2X00 A;  2BYN A;  3WIP A;  3UU5 A;  3C79 A;  2XQ9 A;  4ZJS A;  5J5H A;  4ZK4 A;  3SH1 A;  2Y54 A;  2ZJU A;  3PMZ A;  2BYQ A;  2WNC A;  3PEO A;  4LML A;  4QH1 A;  4WV9 A;  4AFG A;  5BRX A;  2XZ6 A;  5LXB A;  4HFH A;  4HFE A;  5HEG A;  5L4H A;  5HEO A;  2W8G A;  2XQ6 A;  2BG9 E;  3RQU A;  4PIR A;  3WTO A;  3TLS A;  5SYO A;  3SQ9 A;  4HFC A;  4ZRU A;  4ZZB A;  4ZR6 A;  5AFJ A;  2BYR A;  4B5D A;  5AFH A;  5J5I A;  5AFL A;  5AFM B;  2BG9 A;  3IGQ A;  2X00 D;  4ZZC A;  3GUA A;  4ALX A;  2BYP A;  3TLW A;  3UU6 A;  3ZDH A;  3TLV A;  5IUX A;  2QC1 B;  2BYS A;  2WN9 A;  4QAC A;  5HEJ A;  4FRR A;  4A97 A;  4ILB A;  4Z91 A;  4HQP A;  4NZB A;  1I9B A;  4QAB A;  3WTH A;  5BW2 A;  5KE4 A;  2XQA A;  4LMJ A; 
#chains in the Genus database with same CATH topology
 2WZY A;  4UM1 A;  5J5G A;  5BP0 A;  4AFH A;  4IL9 A;  3LSV A;  3TLT A;  4EZ1 A;  5HCJ A;  4BFQ A;  4QH5 A;  2YOE A;  3TLU A;  5AIN A;  2XQ3 A;  5HCM A;  3UU4 A;  3ZKR A;  3RQW A;  2XNT A;  2UZ6 A;  4TWD A;  5J5F A;  2Y58 A;  2Y56 A;  4UY2 A;  3JAD A;  4X5T A;  2WNL A;  2XYS A;  4HFD A;  2ZJV A;  3WTJ A;  2WNJ A;  2BJ0 A;  4LMK A;  3WTL A;  5FJV A;  2XNU A;  2YMD A;  4QH4 A;  4ZK1 A;  2PGZ A;  3SQ6 A;  2C9T A;  3UU3 A;  5AFM A;  4Z90 A;  5AFK A;  2Y7Y A;  2BG9 B;  2VL0 A;  5JME A;  2XNV A;  2YN6 A;  3P4W A;  4QAA A;  5CFB A;  5LG3 A;  3JAE A;  4IRE A;  3UQ4 A;  3WTM A;  1UV6 A;  2XQ5 A;  2XQ4 A;  3EAM A;  3JAF A;  3P50 A;  5HEH A;  3U8L A;  5AFN A;  4TWH A;  4UXU A;  3RI5 A;  4HFI A;  4ILC A;  5HEU A;  4HFB A;  3UQ7 A;  4F8H A;  3C84 A;  3EHZ A;  4XHE A;  4IL4 A;  2BR8 A;  4UM3 P;  3U8K A;  5L4E A;  2Y57 A;  4COF A;  5KZU A;  5J0Z A;  3SIO A;  3RIA A;  4TNW A;  4TWF A;  3UU8 A;  3U8J A;  2XQ7 A;  2PH9 A;  2W8F A;  2YME A;  2BG9 C;  4DBM A;  3UUB A;  3U8N A;  4UM3 A;  3WTN A;  3ZDG A;  4AFT A;  2XQ8 A;  3EI0 A;  4ILA A;  3RHW A;  4UM3 S;  4BQT A;  5L47 A;  5CO5 A;  5TVC A;  1UX2 A;  3U8M A;  2XZ5 A;  1UW6 A;  4XK9 A;  4TNV A;  2YKS A;  4D01 A;  2BR7 A;  3T4M A;  2XYT A;  3WTK A;  4A98 A;  4ZJT A;  3WTI A;  4NPP A;  3RIF A;  2X00 A;  2BYN A;  3WIP A;  3UU5 A;  3C79 A;  2XQ9 A;  4ZJS A;  5J5H A;  4ZK4 A;  3SH1 A;  2Y54 A;  2ZJU A;  3PMZ A;  2BYQ A;  2WNC A;  3PEO A;  4LML A;  4QH1 A;  4WV9 A;  4AFG A;  5BRX A;  2XZ6 A;  5LXB A;  4HFH A;  4HFE A;  5HEG A;  5L4H A;  5HEO A;  2W8G A;  2XQ6 A;  2BG9 E;  3RQU A;  4PIR A;  3WTO A;  3TLS A;  5SYO A;  3SQ9 A;  4HFC A;  4ZRU A;  4ZZB A;  4ZR6 A;  5AFJ A;  2BYR A;  4B5D A;  5AFH A;  5J5I A;  5AFL A;  5AFM B;  2BG9 A;  3IGQ A;  2X00 D;  4ZZC A;  3GUA A;  4ALX A;  2BYP A;  3TLW A;  3UU6 A;  3ZDH A;  3TLV A;  5IUX A;  2QC1 B;  2BYS A;  2WN9 A;  4QAC A;  5HEJ A;  4FRR A;  4A97 A;  4ILB A;  4Z91 A;  4HQP A;  4NZB A;  1I9B A;  4QAB A;  3WTH A;  5BW2 A;  5KE4 A;  2XQA A;  4LMJ A; 
#chains in the Genus database with same CATH homology
 2WZY A;  4UM1 A;  5J5G A;  5BP0 A;  4AFH A;  4IL9 A;  3LSV A;  3TLT A;  4EZ1 A;  5HCJ A;  4BFQ A;  4QH5 A;  2YOE A;  3TLU A;  5AIN A;  2XQ3 A;  5HCM A;  3UU4 A;  3ZKR A;  3RQW A;  2XNT A;  2UZ6 A;  4TWD A;  5J5F A;  2Y58 A;  2Y56 A;  4UY2 A;  3JAD A;  4X5T A;  2WNL A;  2XYS A;  4HFD A;  2ZJV A;  3WTJ A;  2WNJ A;  2BJ0 A;  4LMK A;  3WTL A;  5FJV A;  2XNU A;  2YMD A;  4QH4 A;  4ZK1 A;  2PGZ A;  3SQ6 A;  2C9T A;  3UU3 A;  5AFM A;  4Z90 A;  5AFK A;  2Y7Y A;  2BG9 B;  2VL0 A;  5JME A;  2XNV A;  2YN6 A;  3P4W A;  4QAA A;  5CFB A;  5LG3 A;  3JAE A;  4IRE A;  3UQ4 A;  3WTM A;  1UV6 A;  2XQ5 A;  2XQ4 A;  3EAM A;  3JAF A;  3P50 A;  5HEH A;  3U8L A;  5AFN A;  4TWH A;  4UXU A;  3RI5 A;  4HFI A;  4ILC A;  5HEU A;  4HFB A;  3UQ7 A;  4F8H A;  3C84 A;  3EHZ A;  4XHE A;  4IL4 A;  2BR8 A;  4UM3 P;  3U8K A;  5L4E A;  2Y57 A;  4COF A;  5KZU A;  5J0Z A;  3SIO A;  3RIA A;  4TNW A;  4TWF A;  3UU8 A;  3U8J A;  2XQ7 A;  2PH9 A;  2W8F A;  2YME A;  2BG9 C;  4DBM A;  3UUB A;  3U8N A;  4UM3 A;  3WTN A;  3ZDG A;  4AFT A;  2XQ8 A;  3EI0 A;  4ILA A;  3RHW A;  4UM3 S;  4BQT A;  5L47 A;  5CO5 A;  5TVC A;  1UX2 A;  3U8M A;  2XZ5 A;  1UW6 A;  4XK9 A;  4TNV A;  2YKS A;  4D01 A;  2BR7 A;  3T4M A;  2XYT A;  3WTK A;  4A98 A;  4ZJT A;  3WTI A;  4NPP A;  3RIF A;  2X00 A;  2BYN A;  3WIP A;  3UU5 A;  3C79 A;  2XQ9 A;  4ZJS A;  5J5H A;  4ZK4 A;  3SH1 A;  2Y54 A;  2ZJU A;  3PMZ A;  2BYQ A;  2WNC A;  3PEO A;  4LML A;  4QH1 A;  4WV9 A;  4AFG A;  5BRX A;  2XZ6 A;  5LXB A;  4HFH A;  4HFE A;  5HEG A;  5L4H A;  5HEO A;  2W8G A;  2XQ6 A;  2BG9 E;  3RQU A;  4PIR A;  3WTO A;  3TLS A;  5SYO A;  3SQ9 A;  4HFC A;  4ZRU A;  4ZZB A;  4ZR6 A;  5AFJ A;  2BYR A;  4B5D A;  5AFH A;  5J5I A;  5AFL A;  5AFM B;  2BG9 A;  3IGQ A;  2X00 D;  4ZZC A;  3GUA A;  4ALX A;  2BYP A;  3TLW A;  3UU6 A;  3ZDH A;  3TLV A;  5IUX A;  2QC1 B;  2BYS A;  2WN9 A;  4QAC A;  5HEJ A;  4FRR A;  4A97 A;  4ILB A;  4Z91 A;  4HQP A;  4NZB A;  1I9B A;  4QAB A;  3WTH A;  5BW2 A;  5KE4 A;  2XQA A;  4LMJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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